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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

PSNA College of Engineering and Technology


(An Autonomous Institution Approved by AICTE and Affiliated to Anna University, Chennai)

Dindigul – 624 622

M.E: BIOMEDICAL ENGINEERING

Curriculum for Regulations 2022


(Choice Based Credit System)

For the Students admitted in the Academic year 2022-23 onwards

November 2022
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

PSNA College of Engineering & Technology, Dindigul – 624 622.


(An Autonomous Institution Approved by AICTE and Affiliated to Anna University, Chennai)

REGULATIONS 2022
CHOICE BASED CREDIT SYSTEM

M.E.BIOMEDICAL ENGINEERING

I. PROGRAM EDUCATIONAL OBJECTIVES (PEOs)

1. To enhance the skills of graduates to design a variety of electronic or computer based


devices and develop software for applications including biomedical instrumentation,
medical imaging, physiological measurement and biomedical signal processing.

2. To enable the graduates to acquire technical knowledge and skills required for
Biomedical Engineering that meets industrial and hospital requirements.

3. To enable graduates to effectively involve themselves in product development for


solving Biomedical Engineering cutting-edge technology problems.

4. To facilitate the graduates to exhibit leadership skills, make decisions with societal and
ethical responsibilities, function and communicate effectively in multidisciplinary
settings.

5. To enable the graduates to recognize the need for lifelong learning, enhance their
technical competencies throughout their career and become successful Entrepreneurs.

II. PROGRAM OUTCOMES (POs)

1. Research aptitude: An ability to independently carry out research/investigation and


development work to solve practical problems.
2. Technical documentation: An ability to write and present a substantial technical
report/document.
3. Technical competence: Students should be able to demonstrate a degree of mastery
over the area as per the specialization of the program. The mastery should be at a
level higher than the requirements in the appropriate bachelor program.
4. Engineering Design Apply knowledge of mathematics, science, and engineering to
design, experiment, analyze and interpretation of health care devices.
5. Environment and Society: Demonstrate leadership in their respective careers in
biomedical engineering or interrelated areas of industry, government, academia, and
clinical practice and understanding of professional and ethical responsibility.
6. Life-long Learning: Continuously update knowledge to bridge the gap between
healthcare / Medicine and Technology.
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

PSNA COLLEGE OF ENGINEERING & TECHNOLOGY, DINDIGUL


(An Autonomous Institution Affiliated To Anna University)
REGULATIONS 2022
M.E-BIOMEDICAL ENGINEERING
CHOICE BASED CREDIT SYSTEM
CURRICULA FOR SEMESTERS I TO IV

SEMESTER-I
S. COURSE CATE- PERIODS PER TOTAL
NO. CODE COURSE TITLE GORY WEEK CONTACT CREDITS
L T P PERIODS
THEORY
1. MA1115 Algebra, Optimization and Fourier FC 3 1 0 4 4
Transform
2. RM1122 Research Methodology and IPR RMC 3 0 0 3 3
3. BM1113 BioSignal Processing PCC 3 0 0 3 3
4. BM1114 Human Anatomy and Physiology PCC 3 0 0 3 3
5. BM1115 Applied Medical Image Processing PCC 3 0 2 5 4
6. BM1116 Bio Medical Sensors & PCC 3 0 0 3 3
Instrumentation
7. Audit Course–I* AC 2 0 0 2 0
PRACTICALS
8. BM1181 Clinical Instrumentation and Design PCC 0 0 3 3 1.5
Laboratory
9. BM1182 BioSignal Processing Laboratory PCC 0 0 3 3 1.5
TOTAL 20 1 8 29 23
*Audit course is optional
SEMESTER II
S. COURSE CATE- PERIODS TOTAL
NO. CODE COURSE TITLE GORY PER WEEK CONTACT CREDITS
L T P PERIODS
THEORY
1. BM1211 Medical Device Design PCC 3 0 0 3 3
2. BM1212 Biomaterials and Biomechanics PCC 3 0 0 3 3
3. BM1213 Medical Imaging Systems PCC 3 0 0 3 3
4. BM1214 AI and Machine Learning PCC 3 0 2 5 4
5. Professional Elective I PEC 3 0 0 3 3
6. Professional Elective II PEC 3 0 0 3 3
7. Audit Course–II* AC 2 0 0 2 0
PRACTICALS
8. BM1281 Medical Device Design Laboratory PCC 0 0 4 4 2
9. BM1282 Term Paper Writing and Seminar EEC 0 0 2 2 1
TOTAL 20 0 8 28 22
*Audit course is optional

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

SEMESTER III
PERIODS TOTAL
S. COURSE COURSE TITLE CATE- PER WEEK CONTACT CREDITS
NO. CODE GORY L T P PERIODS
THEORY
1. Professional Elective III PEC 3 0 0 3 3
2. Professional Elective IV PEC 3 0 2 5 4
3. Open Elective OEC 3 0 0 3 3
PRACTICALS
4. BM1381 Hospital / Biomedical Industry EEC 0 0 4 4 2
Training
5. BM1391 Project Work I EEC 0 0 12 12 6

TOTAL 9 0 18 27 18

SEMESTER IV
PERIODS TOTAL
S. COURSE COURSE TITLE CATE- PER WEEK CONTACT CREDITS
NO. CODE GORY L T P PERIODS

PRACTICALS
1. BM1491 Project Work II EEC 0 0 24 24 12
TOTAL 0 0 24 24 12
TOTAL NO. OF CREDITS: 75

PROFESSIONAL ELECTIVES
SEMESTER II, PROFESSIONAL ELECTIVES – I
S. COURSE CATE- PERIODS TOTAL
NO. CODE COURSE TITLE GORY PER WEEK CONTACT CREDITS
L T P PERIODS
1. BM1231 Diagnostic and Therapeutic PEC 3 0 0 3 3
Equipments
2. BM1232 Rehabilitation Engineering PEC 3 0 0 3 3
3. BM1233 Medical Optics PEC 3 0 0 3 3
4. BM1234 Human Assist Devices PEC 3 0 0 3 3
5. BM1235 Medical Device Standards and PEC 3 0 0 3 3
Regulation
6. BM1236 Nuclear Medicine PEC 3 0 0 3 3

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

SEMESTER II, PROFESSIONAL ELECTIVES – II

S. COURSE CATE- PERIODS PER TOTAL


NO. CODE COURSE TITLE GORY WEEK CONTACT CREDITS
L T P PERIODS
1. BM1241 Telehealth technology PEC 3 0 0 3 3
2. BM1242 Medical Robotics PEC 3 0 0 3 3
3. BM1243 Wearable Technology PEC 3 0 0 3 3
4. BM1244 Medical Ethics and Standards PEC 3 0 0 3 3
5. BM1245 Brain Computer Interface PEC 3 0 0 3 3
6. BM1246 Biomedical Micro Devices PEC 3 0 0 3 3

SEMESTER III, PROFESSIONAL ELECTIVES – III


S. COURSE CATE- PERIODS PER TOTAL
NO. CODE COURSE TITLE GORY WEEK CONTACT CREDITS
L T P PERIODS
1. BM1331 Hospital Planning, Organization PEC 3 0 0 3 3
and Management
2. BM1332 Human Resource Management PEC 3 0 0 3 3
in Hospitals
3. BM1333 Hospital Waste management PEC 3 0 0 3 3
4. BM1334 Quality Assurance and Patient PEC 3 0 0 3 3
Safety standards in Hospitals
5. BM1335 Tissue Engineering PEC 3 0 0 3 3
6. BM1336 Troubleshooting In Medical PEC 3 0 0 3 3
Instruments

SEMESTER III, PROFESSIONAL ELECTIVES – IV


S. COURSE CATE- PERIODS PER TOTAL
NO. CODE COURSE TITLE GORY WEEK CONTACT CREDITS
L T P PERIODS
Embedded System and Internet
1. BM1341 of Things for Biomedical PEC 3 0 2 5 4
Applications
2. BM1342 Medical Informatics PEC 3 0 2 5 4
3. BM1343 Pattern Recognition Techniques PEC 3 0 2 5 4
and Applications
4. BM1344 Data Analytics for Health Care PEC 3 0 2 5 4
Technologies
5. BM1345 Virtual/Augmented Reality PEC 3 0 2 5 4
6. BM1346 Physiological Modelling And PEC 3 0 2 5 4
Computation

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

SEMESTER III, OPEN ELECTIVES–I


S. COURSE CATE- PERIODS PER TOTAL
NO. CODE COURSE TITLE GORY WEEK CONTACT CREDITS
L T P PERIODS
1. ST1O12 Water, Sanitation and Health OEC 3 0 0 3 3
2. PX1343 Smart Grid OEC 3 0 0 3 3
3. CP1342 Deep Learning OEC 3 0 0 3 3
4. BA1O12 Micro and Small OEC 3 0 0 3 3
BusinessManagement
5. VL1346 DSP Integrated Circuit OEC 3 0 0 3 3

AUDIT COURSES (AC)


Registration for any of these courses is optional to students

S.No COURSE COURSE TITLE PERIODS PER CREDITS


CODE WEEK
1. AC1A61 English for Research Paper Writing 2 0 0 0
2. AC1A62 Disaster Management 2 0 0 0
3. AC1A63 Constitution of India 2 0 0 0
4. AC1A64 நற் றமிழ் இலக்கியம் 2 0 0 0

FOUNDATION COURSES (FC)

S.No COURSE COURSE TITLE PERIODS PER CREDITS SEMESTER


CODE WEEK
Algebra, Optimization And
1. MA1115 3 1 0 4 1
Fourier Transform

RESEARCH METHODOLOGY AND IPR COURSES (RMC)

S.No COURSE COURSE TITLE PERIODS PER CREDITS SEMESTER


CODE WEEK
1. RM1122 Research Methodology and IPR 3 0 0 3 1

EMPLOYABILITY ENHANCEMENT COURSES (EEC)

S.No COURSE COURSE TITLE PERIODS PER CREDITS


CODE WEEK
1. BM1282 Term Paper writing and Seminar 0 0 2 1 II
2. BM1381 Hospital / Biomedical Industry III
Training 0 0 4 2
3. BM1391 Project Work I 0 0 12 6 III
4. BM1491 Project Work II 0 0 24 12 IV

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

SUMMARY

S.NO NAME OF THE PROGRAMME: M.E-BIOMEDICAL ENGINEERING


SUBJECT AREA CREDITS PER SEMESTER TOTAL CREDITS
I II III IV
1. FC 04 00 00 00 04
2. PCC 16 15 00 00 31
3. PEC 00 06 07 00 13
4. RMC 03 00 00 00 03
5. OEC 00 00 03 00 03
6. EEC 00 01 08 12 21
7. Non Credit/Audit
Course 00 00 00 00 00
TOTAL CREDITS 23 22 18 12 75

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

MA1115 ALGEBRA, OPTIMIZATION AND FOURIER TRANSFORM L T P C


31 0 4
COURSE OBJECTIVES:
 To encourage students to develop a working knowledge of the central ideas of Linear
Algebra.
 To enable students to understand the concepts of Probability and Random Variables.
 To make students understand the notion of a Markov chain, and how simple ideas of
conditional probability and matrices can be used to give a thorough and effective account of
discrete-time Markov chains.
 To familiarize the students with the formulation and construction of a mathematical model
for a linear programming problem in real life situation.
 To introduce the Fourier Transform as an extension of Fourier techniques on periodic
functions and to solve partial differential equations.
UNIT I LINEAR ALGEBRA 12

Vector spaces – Norms – Inner products – Eigen values using QR transformations – QR


factorization – Generalized eigenvectors – Canonical forms – Singular value decomposition and
applications.

UNIT II ONE DIMENSIONAL RANDOM VARIABLES 12

Random variables – Probability function – Moments – Moment generating functions and their
properties – Binomial, Poisson, Geometric, Uniform, Exponential, Gamma and Normal
distributions – Function of a Random Variable.

UNIT III RANDOM PROCESSES 12

Classification – Auto correlation – Cross correlation - Stationary random process – Markov


process – Markov chain – Poisson process.

UNIT IV LINEAR PROGRAMMING 12

Formulation – Graphical solution – Simplex method – Two phase method – Transportation and
Assignment models.

UNIT V FOURIER TRANSFORM FOR PARTIAL DIFFERENTIAL EQUATIONS 12

Fourier transforms: Definitions, properties – Transform of elementary functions, Dirac Delta


functions – Convolution theorem, Parseval’s identity – Solutions to partial differential equation:
Heat equations, Wave equations, Laplace and Poisson’s equations.

TOTAL: 60 PERIODS
REFERENCES:
1. Andrews, L. C. and Philips. R.L., “Mathematical Techniques for engineering and scientists”,
Prentice Hall of India, New Delhi,2006.
2. Bronson, R.,” Matrix Operation”, Schaum’s outline series, Tata McGrawHill, New York,2011.
3. O’Neil P.V., “Advanced Engineering Mathematics”, Cengage Learning”, 8 th Edition, India,
2017.
4. Oliver C. Ibe, “Fundamentals of Applied Probability and Random Processes”, Academic Press,
Boston, 2014.
5. Sankara Rao,K., “ Introduction to partial differential equations” Prentice Hall of India Pvt. Ltd.,
3rd Edition, New Delhi,2010.
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

6. Taha H.A., “Operations Research: An Introduction”, Ninth Edition, Pearson Education, Asia,
10th Edition, New Delhi, 2017.
COURSE OUTCOMES:

CO1: Apply the concepts of linear algebra to solve practical problems.


CO2: Use the ideas of probability and random variables in solving engineering problems.
CO3: Classify various random processes and solve problems involving stochastic processes.
CO4: Formulate and construct mathematical models for linear programming problems and
solve the transportation and assignment problems.
CO5: Apply the Fourier transform methods of solving standard partial differential equations.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 2 2 3 - 1
2 3 2 2 3 - 1
3 3 2 2 3 - 1
4 3 2 2 3 - 1
5 3 2 2 3 - 1
Low (1); Medium (2); High (3)

RM1122 RESEARCH METHODOLOGY AND IPR


L T P C
3 0 0 3
COURSE OBJECTIVES:

 To impartawareness on the significance, approaches and process of research.


 To provide guidelines in the identification of research goals aims, objectives and enrich the
knowledge base in the selection of appropriate data collection method.
 To make acquainted with the tools and techniques for the selection of data collection,
processing methods, analysis and to develop writing skills with publication ethics.
 To provide adequate knowledge of law of patent and copyrights, and IPR
 To be conversed with IPR Laws and patenting process
UNIT I INTRODUCTION TO RESEARCH METHODOLOGY 9

Fundamentals of Research: Objectives of Research - Types of Research - Research Approaches


– Significance - Research Methods versus Methodology - Research and Scientific Method
Overview of Research Process: Problem Identification/Selection - Review of Literature -
Defining the Research Problem– Data Collection - Data Analysis - Documentation.

UNIT II RESEARCH DESIGN 9

Research Plan: Need – Features – Framework - Components – Activity-Time (Gantt) Chart - Data
Collection: Data types - Sampling - Measurement Scales – Data Collection Methods - Selection
of Appropriate Method for Data Collection.

UNIT III DATA ANALYSIS AND DOCUMENTATION 9

Research Techniques and Tools: Basics of Statistics (Mean, Mode, Median; Coefficient of
Variation, Standard deviation; Correlation, Least squares fitting methods) – ANOVA-Multivariate
analysis - Testing of Hypothesis - Overview of software packages for data analysis (Example:
SPSS, R-Programming)
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

Documentation: Types of Reports - Techniques of Interpretation - Significance of Report Writing


– Guidelines for Writing Report (Format, Contents and Chapters. Referencing,
Acknowledgement, Appendices, etc.) – Publication ethics - Software for Plagiarism and
Language checking.
UNIT IV INTELLECTUAL PROPERTY RIGHTS 9

Introduction - Types of Intellectual Property- Origin and Development- An Overview: Copyrights


– Trademarks – Patents – Designs – Utility – Models - Trade Secrets - Geographical Indications –
IPR Development Process.

UNIT V PATENTS 9

Introduction to Patent Law – Indian Patent Law: An Overview - Concept of Patent - Product /
Process Patents & Terminology - Procedure for Filing of Patent Application and Types of
Applications.
TOTAL: 45 PERIODS
REFERENCES:
1. C.R.Kothari and Gaurav Garg, “Research Methodology: Methods and Techniques” New
Age International Publications, 3rd Edition 2014 (UNIT I to UNIT III).
2. Ranjit Kumar, “Research Methodology a step-by-step guide for beginners”, SAGE
publications Ltd 3rd Edition 2011.
3. Stuart Melville and Wayne Goddard, “Research Methodology: An Introduction for
Science & Engineering students”, Juta and Co., Limited, 1st Edition, 1996.
4. William M. Trochim, “Research Methods Knowledge Base”, Atomic Dog publishing, 1st
Edition, 2005.
5. Prasad Karhad, “How to Patent and Idea in India”, 2018.
6. Dr. KanthaBabu, “Textbook on Intellectual Property Rights”, Centre for Intellectual
Property Rights, Anna University, Chennai, 2nd Edition, 2020.
7. Professional Programme Intellectual Property Rights, Law and practice, The Institute of
Company Secretaries of India, Statutory body under an Act of parliament, September
2013 (UNIT IV & UNIT V).

COURSE OUTCOMES:
On completion of the course the student would be able to:
CO1: Demonstrate the components and process of research.
CO2: Select methods for data collection, processing, analysis and formulate Research Problems
with unambiguous objective(s) and assumptions, and mark out the scope the research.
CO3: Develop / Design a research plan with procedure and prepare a research paper/ well-
structured thesis.
CO4: Illustrate various IPR procedures, laws and process of patent filing.
CO5: Do patent search and file copy rights, trademarks and patents.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 1 - - - -
2 1 - - 3 - -
3 1 - 2 1 - 1
4 1 - 1 1 2 2
5 1 - 1 1 - 2
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1113 BIO SIGNAL PROCESSING L T P C


COURSE OBJECTIVES: 3 0 0 3

 To introduce the characteristics of different bio signals


 To discuss linear and non-linear filtering techniques to extract desired information.
 To demonstrate the significance of wavelet detection applied in bio signal processing.
 To extract the features from the bio signal.
 To introduce techniques for automated classification and decision making to aid diagnosis.

UNIT I INTRODUCTION TO BIO SIGNAL 6

Characteristics of some dynamic biomedical signals, Noises- random, structured and


physiological noises, non-stationary process, Filtering- Fundamental concepts of Filtering, Time
domain Filters, Frequency Domain filters.

UNIT II TIME SERIES ANALYSIS AND SPECTRAL ESTIMATION 12

Time series analysis – linear predictive models, process order estimation, Segmentation - fixed
segmentation and adaptive segmentation, Application in EEG, PCG and HRV signals. Estimation
of mean of finite time signals. Spectrum – Power Spectral Density function, Cross-Spectral
Density, Coherence function, Cepstrum and Homomorphic filtering, Blackman Turkey method,
Application in Heart rate variability, PCG signals.

UNIT III ADAPTIVE FILTERING AND WAVELET DETECTION 9

Filtering – LMS adaptive filter, RLS adaptive filter, adaptive noise cancelling in ECG, improved
adaptive filtering in FECG, Muscle contraction interference. Wavelet detection in ECG –
structural features, matched filtering, adaptive wavelet detection, detection of overlapping
wavelets.

UNIT IV ANALYSIS OF BIOSIGNAL 9

Removal of artifact – ECG, Event detection –ECG, P Wave, QRS complex, T wave, Correlation
analysis of EEG signals, Average of Signals-PCG and ECG.

UNIT V BIOSIGNAL CLASSIFICATION AND RECOGNITION 9

Signal classification and recognition – Statistical signal classification, linear discriminate


function, direct feature selection and ordering, Back propagation neural network based
classification.
Case study: 1. Various methods used to extract features from EEG signal
Case Study 2: Diagnosis and monitoring of sleep apnea
TOTAL: 45 PERIODS
REFERENCES:
1. P.RameshBabu, “Digital Signal Processing, Sixth Edition, Scitech publications, Chennai, 2014.
2. Raghuveer M. Rao and AjithS.Bopardikar, Wavelets transform – Introduction to theory and
its applications, Pearson Education, India 2000.
3. Rangaraj M. Rangayyan, 2nd edition “Biomedical Signal Analysis-A case study approach”,
Wiley- Interscience /IEEE Press, 2015.
4. Emmanuel C. Ifeachor, Barrie W.Jervis, second edition, “Digital Signal processing- A Practical
Approach” Pearson education Ltd., 2002.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

5. Willis J.Tompkins, Biomedical Digital Signal Processing, Prentice Hall of India, New Delhi,
2006.

COURSE OUTCOMES:
At the end of the course students will be able to
CO1: Analyse the different types of signals & systems.
CO2: Analyse signals in time series domain & estimate the spectrum.
CO3: Understand the significance of wavelet detection applied in bio signal processing.
CO4: Extract the features from bio signal.
CO5: Describe the performance of the classification of bio signals.
CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 1 2 3 3 2
2 2 1 1 3 2 2
3 2 1 2 3 3 2
4 2 1 2 2 2 2
5 3 1 3 3 3 2
Low (1); Medium (2); High (3)

BM1114 HUMAN ANATOMY AND PHYSIOLOGY L T P C


3 0 0 3
COURSE OBJECTIVES:

 To identify all the organelles of an animal cell and their function.


 To understand the structure and functions of the different types of systems of the human
body.
 To understand about sensory organs and accessory organs of human being.
 To demonstrate their knowledge of importance of anatomical features and physiology of
Human systems.
 Gain knowledge in regulatory mechanism of human body.

UNIT I ORGANIZATION OF THE HUMAN BODY 9

Organization of the human body: from atoms to the entire organism. Anatomical directions and
planes. Cell structures and functions – Plasma membrane and sub-organelles. Cell membrane
transport. Cell to cell signaling, Cell cycle and regulations. Action potential, Homeostasis, Types
of specialized tissues.

UNIT II SKELETAL, MUSCULAR AND RESPIRATORY SYSTEMS 9

Skeletal: Types of Bone and function – Physiology of Bone formation – Division of Skeleton –
Types of joints and function – Types of cartilage and function. Muscular: Parts of Muscle –
Movements. Respiratory: Parts of Respiratory Systems – Types of respiration - Mechanisms of
Breathing – Regulation of Respiration.

UNIT III CARDIOVASCULAR, LYMPHATIC AND ENDOCRINE SYSTEMS 9

Cardiovascular: Structure of Heart, Conducting System of Heart – Properties of Cardiac Muscle -


Cardiac Cycle – Types of Blood vessel – Regulation of Heart rate and Blood pressure. Blood:
Components of Blood and functions - Lymphatic: Types of Lymphatic organs and vessels –
Functions. Endocrine: Pituitary and Thyroid glands.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT IV NERVOUS, SENSE ORGANS AND REPRODUCTIVE SYSTEMS 9

Nervous: Structure, types and properties of Neuron, Mechanism of Nerve impulse. Brain:
Structure and parts of brain – central and peripheral nervous system – Reflex mechanism.
Sense: Structure and functions of eye and ear. Reproductive: Anatomy of testis and ovary.

UNIT V DIGESTIVE AND URINARY SYSTEMS 9

Digestive: Organs of Digestive system – Digestion and Absorption. Urinary: Structure of Kidney
and Nephron – Mechanisms of Urine formation – Regulation of Blood pressure by Urinary
System – Urinary reflex.

TOTAL: 45 PERIODS
REFERENCES:
1. Frederic H. Martini, Judi L. Nath, Edwin F. Bartholomew, Fundamentals of Anatomy and
Physiology. 11th Edition, Pearson Publishers, 2014.
2. Gillian Pocock, Christopher D. Richards, The human Body – An introduction for Biomedical
and Health Sciences, Fifth Edition , Oxford University Press, USA, 2017.
3. William F.Ganong, “Review of Medical Physiology”, 22nd Edition, Mc Graw Hill, New Delhi,
2010.
4. Eldra Pearl Solomon, “Introduction to Human Anatomy and Physiology”, - 4thEdition , W.B.
Saunders Company, 2015.
5. Guyton & Hall, “Medical Physiology”, 13th Edition - Elsevier Saunders, 2015. Elaine.N.Marieb,
"Essential of Human Anatomy and Physiology", Eleventh Edition, Pearson Education, New
Delhi,2015.

COURSE OUTCOMES:

At the end of the course, the students will be able:


CO 1: Explain the general terminology, cell structure and function, histology, gross anatomy,
and physiology related to the various human systems.
CO 2: Acquire knowledge various anatomical parts of the human systems.
CO 3: Understand about interconnectedness of anatomy and physiology of various systems.
CO 4: Acquire knowledge in human organ systems interrelation and apply a holistic approach to
human health.
CO 5: Apply concept and knowledge of human systems to novel technical and/or clinical
scenarios.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 2 2 2 2 2
2 2 2 2 2 2 2
3 2 2 2 1 1 2
4 2 2 2 - 1 1
5 2 1 1 1 1 1
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

L T P C
BM1115 APPLIED MEDICAL IMAGE PROCESSING 3 0 2 4

COURSE OBJECTIVES:

The main learning objective of this course is to prepare the students for:
 To understand the fundamentals of medical image processing techniques.
 To understand the basic concepts of image enhancement, image restoration, morphological
image processing, image segmentation, feature recognition in medical images.
 To provide information about various medical imaging modalities.
 To provide information about classification and image visualization in medical image
processing projects
 To familiarize the student with the image processing facilities in Matlab, Python and
openCV.

UNIT I FUNDAMENTALS OF IMAGE PROCESSING 9

Image perception, MTF of the visual system, Image fidelity criteria, Image model, Image
sampling and quantization – two dimensional sampling theory, Image quantization, Optimum
mean square quantizer, Image transforms – 2D-DFT and other transforms. DFT, DCT, KLT, SVD.

UNIT II MEDICAL IMAGE ENHANCEMENT AND RESTORATION 9

Image Enhancement operation, Noise distributions, Spatial averaging, Directional Smoothing,


Median, Geometric mean, Harmonic mean, Contra harmonic mean filters, Homomorphic
filtering, Color image enhancement. Image Restoration - degradation model, Unconstrained and
constrained restoration, Inverse filtering- Wiener filtering.

UNIT III MEDICAL IMAGE REPRESENTATION 9

Pixels and voxels – algebraic image operations - gray scale and color representation- depth-
color and look up tables - image file formats- DICOM- other formats- Analyze 7.5, NifTI and
Interfile, Image quality and the signal to noise ratio

UNIT IV MEDICAL IMAGE ANALYSIS AND CLASSIFICATION 9

Image segmentation- pixel based, edge based, region based segmentation. Image
representation and analysis, Feature extraction and representation, Statistical, Shape, Texture,
feature and image classification – Statistical, Rule based, Neural Network approaches

UNIT V IMAGE REGISTRATIONS AND VISUALIZATION 9

Image Registration: Rigid body transformation– Affine transformation, Principal axes


registration, Iterative principal axes registration, Feature based registration, Elastic deformation
based registration, Registration of Images from Different modalities, Evaluation of Registration
Methods. Image visualization: 2-D display methods, 3-D display methods, surface and volume
based 3-D display methods – Surface Visualization and Volume visualization, 3-D
Echocardiography, 3D+time Echocardiography, virtual reality based interactive visualization.
TOTAL: 45 PERIODS

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

PRACTICAL EXERCISES:
The following experiments should be performed in OpenCV / Python / Scilab / Matlab Octave /
other Open source software.

LIST OF EXPERIMENTS

1. Preprocessing of medical images


2. Filtering of medical images.
3. Edge detection using Python
4. Segmentation of ROI in medical images
5. Feature extraction in medical images
6. Steganography using OpenCV
7. Medical image fusion
8. Statistical analysis of features
9. Neural network based classification
TOTAL: 30 PERIODS
TOTAL: 75 PERIODS
REFERENCES:
1. Atam P.Dhawan, Medical Image Analysis, 2nd Edition, John Wiley & Sons, Inc.,Hoboken,
New Jersey, 2011.
2. Anil K Jain, Fundamentals of Digital Image Processing, 1st Edition, Pearson Education India,
2015.
3. Rafael C.Gonzalez and Richard E.Woods, Digital Image Processing, 4th Edition,Pearson
Education, 2018.
4. Wolfgang Birkfellner, “Applied Medical Image Processing – A Basic course”, CRC Press, 2011.
5. Geoff Dougherty, Digital Image Processing for Medical Applications, 1st Edition, Cambridge
University Press, 2010.
6. John L.Semmlow, “Biosignal and Biomedical Image Processing Matlab Based applications”
Marcel Dekker Inc.,New York,2004
7. KavyanNajarian and Robert Splerstor, “Biomedical signals and Image processing”,CRC –
Taylor and Francis,New York,2006
8. Milan Sonka et aI, “Image Processing, Analysis and Machine Vision”, Brookes/Cole, Vikas
Publishing House, 2nd edition, 1999
9. RavikanthMalladi, Geometric Methods in Bio-Medical Image Processing (Mathematics and
Visualization), 1st Edition, Springer-Verlag Berlin Heidelberg 2002
10. Joseph V. Hajnal, Derek L.G. Hill and David J. Hawkes, Medical Image Registration, CRC Press,
2001

COURSE OUTCOMES

After the completion of the course the student will be able to


CO1: Apply basic medical image processing algorithms
CO2: Image pre-processing applications that incorporates different concepts of filters for
medical Image Processing and reconstruction of an image.
CO3: Describe the image representation model.
CO4: Analysis of image segmentation, feature extraction and image classification.
CO5: Explore the knowledge in image registration and visualization and possibility of applying
Image Processing concepts in modern hospitals.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 - 2 2 2 1
2 2 1 2 3 2 1
3 1 1 2 2 1 1
4 3 - 2 3 3 2
5 2 1 1 2 1 2
Low (1); Medium (2); High (3)

BM1116 BIO MEDICAL SENSORS AND INSTRUMENTATION


L T P C
3 0 0 3
COURSE OBJECTIVES:

 To understand the purpose of measurement, the methods of measurements, errors


associated with measurements.
 To obtain the knowledge of biosensors in medical field.
 To gain the domain knowledge in bio potential and its measurements.
 To Study the design of bio amplifiers.
 Get familiarized with important medical equipment used in critical care.

UNIT I INTRODUCTION TO MEASUREMENT 11

Measurement System – Instrumentation - Classification and Characteristics of Transducers –


Static and Dynamic - Errors in Measurements and their statistical analysis – Calibration - Primary
and secondary standards.

UNIT II BIO SENSORS 11

Chemical sensors, characteristics, classes of chemical sensors, electrochemical cell, biochemical


sensors, multisensory arrays, RTD materials & range, relative resistance vs. temperature
characteristics, thermistor characteristics, Biomedical applications of temperature sensors.
Active type: Thermocouple - characteristics.

UNIT III BIOPOTENTIAL AND ITS MEASUREMENTS 14

Origin of bio potential and its propagation. Electrode-electrolyte interface, electrode–skin


interface, half-cell potential, impedance, polarization effects of electrode – non polarizable
electrodes. Types of electrodes - surface, needle and micro electrodes and their equivalent
circuits. Biosignals characteristics – frequency and amplitude ranges. ECG – Einthoven’s triangle,
standard 12 lead system. EEG – 10-20 electrode system, unipolar, bipolar and average mode.
EMG– unipolar and bipolar mode.

UNIT IV DESIGN OF BIOAMPLIFIERS 12

Need for bio-amplifier - single ended bio-amplifier, differential bio-amplifier, Impedance


matching circuit, isolation amplifiers – transformer and optical isolation - isolated DC amplifier
and AC carrier amplifier., Power line interference, Right leg driven ECG amplifier, Band pass
filtering.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT V MEDICAL EQUIPMENT 12

Basics of Critical Care Equipment – Bedside monitors, ICU / CCU equipment – Defibrillator and
its types, Pacemaker and its types. Ventilator and its types, Dialysers, Endoscopy, laparoscopy,
Oxygenators.

TOTAL: 60 PERIODS
REFERENCE:

1. Geddes LA and Baker L.E Principals of Applied Biomedical Instrumentation, 3rd Edition, John
Wiley and sons, New york 1989.
2. Joseph J Carr and John Brown Introduction to Biomedical equipment Technology- Pearson
Education 4th edition New Delhi 2001.
3. Khandpur R.S Hand Book of Biomedical Instrumentation – Tata Mc Graw Hill publication ,
New Delhi 3rd edition 2014.
4. Webster J.G Medical Instrumentation application and design – John Wiley and sons New
York 4thedition 2009
5. Leslie Cromwell, Biomedical Instrumentation and measurement, Prentice Hall of India, New
Delhi, 2nd edition, 2015
6. Richard Aston, Principles of Biomedical Instrumentation and Measurement, Merril Publishing
Company, 2002

COURSE OUTCOMES:

On completion of the course, students will be able to:


CO1: Understand the science behind the measurement systems
CO2: Explain the different types of Bio sensors.
CO3: Understand various bio signals and its measurements.
CO4: Design a bio-amplifier.
CO5: Describe various medical equipment used in critical care.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 2 1 2 1 1
2 2 2 2 2 - 1
3 2 1 1 - - 1
4 2 2 2 3 3 2
5 2 3 2 2 2 2
Low (1); Medium (2); High (3)

BM1181 CLINICAL INSTRUMENTATION AND DESIGN LABORATORY


L T P C
0 0 3 1.5
COURSE OBJECTIVES:

 Familiarize the design of preamplifiers and its significance.


 Design various bio signals acquisition amplifiers and Isolation Circuits.
 To Study the various medical equipment used in medical field.
 Study the critical care equipment in medical field.
 Design 3D printing model for medical application.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

LIST OF EXPERIMENTS:

1. Design of pre amplifiers to acquire any Bio-signals


2. Design of ECG amplifier with suitable filter to remove movement artifacts and power line
noise
3. Design of suitable circuit to calculate heart rate
4. Design of optical Isolation Amplifier
5. Measurement of Pulse Rate using suitable device
6. Measurement of Respiratory Rate using Suitable device
7. Study the working of Defibrillator and pacemakers
8. Study of ventilators
9. Study the use of any 2-D and 3-D Modelling Software
10. Develop prototyping using 3D printing
TOTAL: 45 PERIODS

COURSE OUTCOMES:
On completion of the course, students will be able to:
CO1: Design a preamplifier on his own
CO2: Design amplifier and Isolation circuits for any bio signals.
CO3: Obtain the domain knowledge in Basic medical equipment.
CO4: Obtain the domain knowledge in critical care equipment.
CO5: Get familiarized with important of 3D printing in medical field

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 2 3 3 3 3
2 2 2 3 3 3 3
3 2 2 3 3 3 3
4 2 2 3 3 3 3
5 2 2 3 3 3 3
Low (1); Medium (2); High (3)

BM1182 BIO SIGNAL PROCESSING LABORATORY


L T P C
COURSE OBJECTIVES: 0 0 3 1.5

 To understand the analysis of biosignals


 To know the various methods for denoising of biosignals
 To understand the extraction of features in biosignals
 To gain knowledge about biosignal compression
 To detect and classify the abnormalities in biosignals

LIST OF EXPERIMENTS: MATLAB / EQUIVALENT SOFTWARE PACKAGE

1. Removal of noise and artifact using filtering


2. Denoising of biosignals using wavelets
3. Event detection in EEG signals
4. Cepstral analysis of speech signals
5. Feature reduction using PCA
6. Biosignal compression
7. QRS detection using Pan-Tompkins algorithm
8. QRS detection by template correlation
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

9. Heart rate variability analysis in ECG signals


10. Disease classification of biosignals
11. Biosignal analysis in virtual instrumentation platform
12. Plotting Power Spectrum of ECG

MINI PROJECT ON:

1. Noise cancellation using Adaptive filters.


2. Feature extraction in biosignals.
3. Autoregressive modelling of biosignals.
TOTAL: 45 PERIODS

COURSE OUTCOMES:

At the end of the course, learners will be able


CO1: Develop an algorithm for preprocessing of biosignals.
CO2: Perform denoising and analyze the spectral characteristics of biosignals.
CO3: Perform biosignal compression.
CO4: Analyze the biosignals in virtual instrumentation platform.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 2 3 3 1 2
2 3 2 3 3 1 2
3 3 2 3 3 1 2
4 3 2 3 3 1 2
Low (1); Medium (2); High (3)

BM1211 MEDICAL DEVICE DESIGN L T P C


COURSE OBJECTIVES: 3 0 0 3

 To understand about basic design processes of medical device


 To introduce with basics of design, construction and development devices
 To follow a deterministic engineering design process to create new products
 To apply engineering theory to practice
 To perform design transfer and countermeasure development
UNIT I INTRODUCTION 9

Needs finding, problem identification, prior art searches, strategy and concept generation,
estimation, sketching, sketch modelling, machine elements, ergonomics and prototyping.

UNIT II DESIGN OF MEDICAL DEVICES & SYSTEM 9

Medical device classification, bioethics, and privacy, biocompatibility and sterilization


techniques, design of clinical , trials, design control and regulatory requirements, introduction
to specific, medical technologies: biopotentials measurement (EMG, EOG, ECG, EEG), medical
diagnostics (In-vitro diagnostics), medical diagnostics (Imaging), minimally invasive devices,
surgical tools and implants.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT III DEVELOPMENT STRATEGY AND PLANNING 9

Intellectual property strategy – research and development strategy – clinical strategy –


regulatory strategy – quality and process management – reimbursement strategy – marketing
and stakeholder strategy – sales and distribution strategy – competitive advantage and business
strategy.

UNIT IV HARDWARE AND SOFTWARE DESIGN 9

Hardware design, Hardware risk analysis, Design and project merits, Design for six sigma,
software design, software coding, software risk analysis, software metrics, licensing and
alternate pathways.

UNIT V DESIGN TRANSFER AND IPR 9

Transfer to and deliverables. Standard-ISO, IES, Intellectual Property - Patents, Copy rights,
Trademarks, Trade secrets. manufacturing, documents.

TOTAL: 45 PERIODS
REFERENCE:
1. Matthew Bret Weinger, Michael E. Wiklund, Daryle Jean Gardner-Bonneau’Handbook of
Human Factors in Medical Device Design’,CRC press,2010.
2. Peter J. Ogrodnik, “Medical Device Design: Innovation from Concept to Market” Academic
Press Inc; 1st Edition, 2012.
3. Paul H. King, Richard C. Fries, Arthur T. Johnson, “Design of Biomedical Devices and Systems”,
Third Edition, 2014.
4. Stefanos Zenios , Josh Makower , Paul Yock , Todd J. Brinton , UdayN. Kumar , Lyn Denend,
Thomas M. Krummel, “Biodesign: The Process of Innovating Medical Technologies”,
Cambridge University Press; 1 edition, 2009.

COURSE OUTCOMES:

After the completion of the course the student will be able to


CO1: To understand the importance of medical device design
CO2: To understand the designing of medical devices and systems
CO3: To understand development strategy and planning
CO4: To understand hardware and software designing of medical devices.
CO5: To understand design transfer and IPR

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 - 2 2 2 2 -
2 3 - - 2 - 1
3 1 - 2 3 - 2
4 3 2 2 2 - 2
5 3 1 2 2 2 2
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1212 BIOMATERIALS AND BIOMECHANICS


L T P C
COURSE OBJECTIVES: 3 0 0 3

 To introduce concepts of materials, surface and tissue placement in biomaterial functions.


 To understand diverse elements controlling biological responses to materials
 To get the clear understanding of application of mechanics in medicine.
 To study the properties of blood, bone and soft tissues like articular cartilage tendons and
ligaments
 To gain necessary knowledge about accident and injuries.
UNIT I INTRODUCTION TO BIOMATERIALS 9

Definition and classification of biomaterials- Metals, Ceramics, Polymers and Biomimetic


Materials, Composites. Mechanical properties- viscoelasticity, body response to implants, and
wound healing process, Applications of biomaterials in medicine and its failure mechanisms,
artificial organs, 3D printing.

UNIT II STERLIZATION AND TESTING OF BIOMATERIALS 8

Sterilization techniques- ETO, gamma radiation, autoclaving. Effects of sterilization on material


properties. Testing with Tissue Culture – in vitro and in vivo assessment of biocompatibility,
blood compatibility and thromobogenicity. ISO 10993- standard for assessment of
biocompatibility.

UNIT III FLUID AND TISSUE BIOMECHANICS 10

Definition of stress, strain, elasticity, viscosity, kinetics and kinematics. Newton’s law of motion,
viscoelasticity, constitutive equation for Newtonian fluid, Non- Newtonian fluid and Hookean
elastic solid.

Hard Tissues: Structure, composition & mechanical properties of bone, cortical and cancellous
bones, viscoelastic properties, Maxwell & Voight models – anisotropy. Electrical properties of
bone, type of fractures, biomechanics of fracture healing.
Soft Tissues: Structure and functions of Soft Tissues: Cartilage, Tendon, Ligament, and Muscle-
Material Properties and Modeling.

UNIT IV BIOMECHANICS OF JOINT IMPLANTS AND MOVEMENTS 9

General concepts of Implants, classification of implants, Soft tissue replacements and Hard
tissue replacements, Design of Joint replacement – Hip and Knee joint replacement.
Gait analysis, body & limbs: mass & motion characteristics actions, forces transmitted by joints-
normal & disable human body, normal & fast gait on the level. Patterns: Push/Throw
Continuum Biomechanics of push - like motions, Biomechanics of throw - like motions.

UNIT V CARDIAC & RESPIRATORY MECHANICS 9

Cardiovascular system, Mechanical properties of blood vessels: arteries, arterioles, capillaries,


and veins, Artificial heart valves, biological and mechanical valves development, testing of
valves. Alveoli mechanics, Interaction of blood and lung, P-V curve of lung, Breathing
mechanism, Airway resistance, Physics of lung diseases.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

SUGGESTED ACTIVITIES:
1: Stress-strain analysis of hip prosthesis
2: Estimation of hemocompatibility of biomaterials by hemolysis studies
3: Measurement of torque required to tap and screwing in jaw bone.
4: Determination of moment of inertia of human limb using dynamometer.

TOTAL: 45 PERIODS
REFERENCES:
1. Jonathan Black, Biological Performance of Materials- Fundamentals of bio compatibility, 4th
Edition, CRC Press 2005.
2. Larry L. Hench and Julian R. Jones, Biomaterials, Artificial organs, and Tissue Engineering,
2005.
3. Y. C. Fung, Biomechanics: Mechanical properties in living tissues, Springer Verlag, New York
1981.
4. Susan J. Hall, Basics Bio Mechanics 4th Edition, McGraw-Hill Publishing Co, 2002.
5. Subrata pal, Text book of Biomechanics, Viva education private limited, 2009.
6. C. R Ethier and C. A. Simmons, Biomechanics from cells to organisms, Cambridge University
Press, 2007.
7. D. Dawson and Right, Introduction to Bio-mechanics of joints and joint replacement.
8. Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen, Jack E. Lemons, Biomaterial Science;
An Introduction to Materials in Medicine, 2nd Edition, Elsevier Academic Press, San Diego,
2004.
COURSE OUTCOMES

After the completion of the course the student will be able to


CO1. Analyze different types of materials and apply in designing a device.
CO2. Select the materials for designing an implants in tissue replacement.
CO3. To get the clear understanding of application of mechanics in medicine.
CO4. To study the properties of blood, bone and soft tissues like articular cartilage tendons and
ligaments.
CO5. Acquired a conceptual and theoretical framework of the design, development, and
implementation of orthopedic implants.
CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 1 3 1 1 1
2 1 2 2 1 - 1
3 2 2 1 2 - -
4 3 3 2 2 - 1
5 2 2 2 2 2 -
Low (1); Medium (2); High (3)

BM1213 MEDICAL IMAGING SYSTEMS


L T P C
3 0 0 3
COURSE OBJECTIVES:

 To understand the production of x-rays and its application to different medical Imaging.
 To explore the different types of Radio diagnostic techniques.
 To understand the special imaging techniques for visualizing the cross sections of the body.
 To understand the production of Magnetic resonance images for various pulse sequences.
 To realize the importance of image quality assessments for medical imaging systems.
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT I X – RAYS 9

Principle and production of soft X – Rays, X- ray machine and digital radiography, principles of
Angiography and Fluoroscopic Techniques, digital subtraction angiography, mammography.

UNIT II CT AND ULTRASOUND IMAGING 9

CT principle- Multi section Radiography, Computerised Axial Tomography, Type of Detection,


image reconstruction, Spiral CT, Transverse Tomography,3D Imaging. Ultrasonic frequency for
medical application, different modes of Display A, B and M, ultrasonic probes, Real time echo
and 2D scanner.

UNIT III COMPUTER AIDED TOMOGRAPHY 9

Need for sectional images, Principles of sectional scanning, Method of convolution and Back
Propagation, Methods of reconstruction, Multislice CT, artifacts.

UNIT IV MAGNETIC RESONANCE IMAGING AND EMISSION COMPUTED TOMOGRAPHY


IMAGING 9

Principle of MRI, MRI instrumentation, Imaging Different Sections of the Body, Tissue
Characterization, MR Spectroscopy, Functional MRI. Alpha, Beta, Gamma Emission, different
types of Radiation Detectors, Functions of Gamma Camera, PET, SPECT, PET/CT, PET/MRI.

UNIT V QUALITY METRICS FOR IMAGING SYSTEMS 9

Global parameter assessment, spatial – frequency assessment, Image – processing assessment,


Observer assessment, Image discrimination models, figure of merit, Comparing model to human
Performance.
TOTAL: 45 PERIODS
REFERENCES:
1. Richard L. Van Metter, Jacob Beutel, Harold L. Kundel, Handbook of Medical Imaging, Volume
Physics and Psychophysics, SPIE, 2000.
2. Chesney D. N., Chesney M. O. Radio graphic imaging, CBS Publications, New Delhi, 1989.
3. Donald W. McRobbice, Elizabeth A. Moore, Martin J. Grave and Martin R. Prince MRI from
Picture to proton, Cambridge University press, second edition, New York 2007.
4. Frederick W Kremkau, Diagnostic Ultrasound Principles & Instruments, Saunders
Elsevier,2005.
5. Jerry L. Prince, Jnathan M. Links, Medical Imaging Signals and Systems- Pearson Education
Inc. 2014
6. Peggy, W., Roger D. Ferimarch, MRI for Technologists, McGraw Hill, New York, second
edition, 2000.

COURSE OUTCOMES:
Up on completion of the course, students will be able to
CO1:Explain the functionalities and applications of X ray in medicine.
CO2:Demonstrate the images acquisition procedures using CT.
CO3:Explain the suitable projection methods for anatomy and biology specific.
CO4:Demonstrate the applications of magnetic field in the field of medicine.
CO5:Explain the assessment method to quantify the presence of noise in the image.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 1 2 1 2 1 2
2 2 2 1 2 2 1
3 2 2 2 2 1 1
4 2 2 1 2 2 1
5 2 2 2 2 2 2
Low (1); Medium (2); High (3)

BM1214 AI AND MACHINE LEARNING L T P C


3 0 2 4

COURSE OBJECTIVES:

 To introduce the concept of machine learning.


 To learn and apply neural networks for pattern classification and regression problems
 To introduce the ideas of fuzzy sets, fuzzy logic.
 To familiarize with genetic algorithms for seeking global optimum in self-learning situations.
 To introduce the Deep learning concept for medical image analysis.
UNIT I INTRODUCTION TO MACHINE LEARNING 9

Machine Learning – Basic Concepts in Machine Learning – Types of Machine Learning –


Examples of Machine Learning – Applications – Linear Models for Regression – Linear Basis
Function Models – The Bias-Variance Decomposition – Bayesian Linear Regression –
Dimensionality Reduction.

UNIT II NEURAL NETWORKS 9

Biological Neurons and their Artificial models, Learning Rules, Single Layer Perceptron
Classifiers Back Propagation Network, generalized delta rule, Associative Memory, Adaptive
Resonance Theory (ART) Network Descriptions.

UNIT III FUZZY LOGIC SYSTEMS 9

Fuzzy Logic System: Basic of fuzzy logic theory , crisp and fuzzy sets, Basic set operation like
union , interaction , complement , T-norm , T-conorm , fuzzy relations, fuzzy if-then rules , fuzzy
reasoning, Neuro-Fuzzy Modeling: Adaptive Neuro-Fuzzy Inference System (ANFIS) , ANFIS
architecture , Hybrid Learning Algorithm.

UNIT IV EVOLUTIONARY COMPUTATION & GENETIC ALGORITHMS 9

Evolutionary Computation (EC) – Features of EC – Classification of EC – Advantages –


Applications. Genetic Algorithms: Introduction – Biological Background – Operators in GA-GA
Algorithm – Classification of GA – Applications.

UNIT V ADVANCES AND APPLICATIONS 9

Support Vector Machines, RBF Network. Introduction to Deep Learning – Convolutional Neural
Network. Case Study – Neural Network based Classification of Biosignal and Medical Images.

TOTAL: 45 PERIODS
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

PRACTICAL EXERCISES:

1. Implement Simple Programs like vector addition in TensorFlow.


2. Implement a simple problem like regression model in Keras
3. Implement a perceptron in TensorFlow/Keras Environment
4. Implement a Feed-Forward Network in TensorFlow/Keras
5. Implement an Image Classifier using CNN in TensorFlow/Keras.
6. Develop an abnormal detection system for bio signal data using fuzzy logic
7. Develop a system to implement Neural Networks techniques to define predictive models for
Abnormal detection
8. Develop a system that can optimize the solution of the abnormal detection system developed
by fuzzy logic
9. Implement a biosignal/medical image Classifier using CNN
TOTAL: 30 PERIODS
TOTAL: 75 PERIODS
REFERENCES

1. Tom M. Mitchell, “Machine Learning”, McGraw-Hill Education (INDIAN EDITION), 2013.


2. EthemAlpaydin, “Introduction to Machine Learning”, 2nd Ed., PHI Learning Pvt. Ltd., 2013.
3. T. Hastie, R. Tibshirani, J. H. Friedman, The Elements of Statistical Learning, Springer; 1st
edition,2001.
4. Wolfgang Ertel, “Introduction to Artificial Intelligence”, Springer, 2nd Edition, 2017
5. NelloCristianini, John Shawe-Taylor, "An Introduction to Support Vector Machines and Other
Kernel-based Learning Methods”,Cambridge University Press. 2013
6. Timothy Ross, “Fuzzy Logic with Engineering Applications”, Wiley, 2016
7. David E. Goldberg, “Genetic Algorithms in search, Optimization & Machine Learning”,
Pearson Education, 2006
8. Neural Networks and Deep Learning by Michael Nielsen., March 2017
COURSE OUTCOMES:

At the end of this course, the students will be able to:


CO1: Identify and describe machine learning techniques and their roles in building intelligent
system
CO2: Design neural networks for pattern classification and regression problems
CO3: Apply fuzzy logic and reasoning to handle uncertainty and solve engineering problems
CO4: Apply genetic algorithms to optimization problems
CO5: Apply Deep learning concept for biomedical signal analysis and Medical image analysis.
CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 - - 2 2 -
2 1 - - 2 2 -
3 1 - - 3 2 1
4 1 - 2 3 3 1
5 3 - 3 3 3 3
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1281 MEDICAL DEVICE DESIGN LABORATORY


L T P C
0 0 4 2
COURSE OBJECTIVES:

● To understand various voltage protection circuits


● To understand data acquisition and displaying systems
● To gain knowledge about EEG multi-channel acquisition
● To gain knowledge about various noise cancellation systems
● To understand the interfacing mechanism of DSP

LIST OF EXPERIMENTS:

1. Simulation of over voltage protection circuit

2. Simulation of under voltage protection circuit

3. Simulation of instrumentation amplifier

4. Accelerometer data acquisition and displaying system

5. Multichannel data acquisition for EEG recording

6. Simulation of switched capacitor system

7. Modeling and simulation of internal noise cancellation circuit

8. Cross talk cancellation system

9. Serial Interfacing to DSP

10. Parallel interfacing to DSP

11. Gait analysis


TOTAL: 60 PERIODS
COURSE OUTCOMES:
At the end of the course, the student should be able to:
CO1: Design and develop voltage protection circuits
CO2: Develop data acquisition displaying system.
CO3: Attain knowledge in EEG multi channel acquisition method
CO4: Design noise cancellation system
CO5: Develop the interfacing mechanism using DSP
CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 2 1 2 2 1
2 2 2 2 1 2 1
3 2 2 2 1 1 1
4 2 2 1 1 2 2
5 2 2 2 2 2 2
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1282 TERM PAPER WRITING AND SEMINAR LTP C


00 2 1
In this course, students will develop their scientific and technical reading and writing skills that
they need to understand and construct research articles. A term paper requires a student to
obtain information from a variety of sources (i.e., Journals, dictionaries, reference books) and
then place it in logically developed ideas. The work involves the following steps:

1. Selecting a subject, narrowing the subject into a topic

2. Stating an objective

3. Collecting the relevant bibliography (atleast 15 journal papers)

4. Preparing a working outline

5. Studying the papers and understanding the authors contributions and critically analysing

each paper Preparing a working outline

6. Linking the papers and preparing a draft of the paper.

7. Preparing conclusions based on the reading of all the papers

8. Writing the Final Paper and giving final Presentation

Please keep a file where the work carried out by you is maintained.

Activities to be carried out

Activity Instructions Submission week Evaluation

Selection of area of You are requested to select 2nd week 3 % Based on clarity of
interest and Topic an area of interest, topic thought, current
Stating an Objective and state an objective relevance and clarity in
writing
Collecting Information 1. List 1 Special Interest 3rd week 3% ( the selected
about your area & Groups or professional information must be
topic society area specific and of
2. List 2 journals international and
3. List2 conferences, national standard)
symposia or workshops
4. List 1 thesis title
5. List 3 web presences
(mailing lists, forums, news
sites)
6. List 3 authors who
publish regularly in your
area
7. Attach a call for papers
(CFP) from your area.
Collection of Journal 1. You have to provide a 4th week 6% (the list of standard
papers in the topic in complete list of papers and reason for
the context of the references you will be selection)
objective – collect 20 & using- Based on your

25
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

then filter objective –Search various


digital libraries and
Google Scholar
2. When picking papers to
read - try to:
3. Pick papers that are
related to each other in
some ways and/or that are
in the same field so that
you can write a
meaningful survey out of
them
4. Favour papers fromwell-
known journals and
conferences,
5. Favour “first” or
“foundational”papers in the
field (as indicated in
otherpeople’s survey
paper),
6. Favour more recent
papers,
7. Pick a recent survey of
the field so you can quickly
gain an overview,
8. Find relationships with
respect to each other
and to your topic area
(classification scheme
/categorization)
9. Mark in the hard copy
of papers whether
complete work or
section/sections of the
paper are being
considered
Reading and notes for Reading Paper Process 5th week 8% ( the table given
first 5papers 1. For each paper form a shouldindicate your
Tableanswering the understanding of the
following questions: paper and the
2. What is the main topic of evaluation is based on
the articles? your conclusions about
3. What was/were the each paper)
main issue(s) the author
said they want to discuss?
4. Why did the author
claim it was important?
5. How does the work build
on other’s work, in the
author’s opinion?
6. What simplifying

26
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

assumptions does the


author claim to be
making?
7. What did the author do?
8. How did the author
claim they were going to
evaluate their work and
compare it to others?
9. What did the author say
were the limitations of
their research?
10. What did the author
say were the important
directions for future
research? Conclude with
limitations/issues not
addressed by the paper (
from the perspective of
your survey)
Reading and Repeat Reading Paper 6th week 8% (the table given
notes for next5 Process should indicate
papers yourunderstanding of
thepaper and the
evaluationis based on
yourconclusions about
eachpaper)
Reading and Repeat Reading Paper 7th week 8%( the table given
notes for final 5 Process shouldindicate
papers yourunderstanding of
thepaper and the
evaluationis based on
yourconclusions about
eachpaper)
Draft outline 1 and Prepare a draft Outline, 8th week 8%( this component
Linking your survey goals, along will beevaluated based
Papers with a classification/ on thelinking and
categorization classification
diagram among the papers)
Abstract Prepare a draft abstract and 9th week 6%(Clarity, purpose
give a presentation andconclusion)6%
Presentation &
VivaVoce
Introduction Write an introduction and 10th week 5%( clarity)
Background background sections
Sections of the paper Write the sections of your 11thweek 10%(this component
paper based on the will be evaluated based
classification/categorization on thelinking and
diagram in keeping with the classificationamong the
goals of your survey papers)
Your conclusions Write your conclusions and 12th week 5% ( conclusions –
future work clarity and your ideas)
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

Final Draft Complete the final draft of 13th week 10% (formatting,
your paper English, Clarity and
linking) 4% Plagiarism
Check Report
Seminar A brief 15 slides on your 14th & 15th week 10%(based on
paper presentation and Viva-
voce)
TOTAL: 30 PERIODS

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 2 1 2 2 1
2 2 2 2 1 2 1
3 2 2 2 1 1 1
4 2 2 1 1 2 2
5 2 2 2 2 2 2
Low (1); Medium (2); High (3)

BM1231 DIAGNOSTIC AND THERAPEUTIC EQUIPMENTS L T P C


COURSE OBJECTIVES: 3 0 0 3
 To study the measurement of various biopotential and non-electrical parameters.
 To explore the various functional blocks present is cardiac care units and various assist
devices
 To develop an understanding of the physiotherapy and diathermy equipment.
 To study the electrical safety in the hospital environment
UNIT I BIO POTENTIAL RECORDING 9

Cell Potential-Half-cell potential, Electrodes-types of electrodes, Signal Conditioning circuits-


Characteristics of Amplifiers, Differential Amplifiers, Filters, Isolation Amplifier, Design concepts.
ECG, EEG, EMG, PCG, EOG, lead system and recording methods, typical waveform, frequency
spectrum, abnormal waveforms. Evoked response.

UNIT II MEASUREMENT OF NON ELECTRICAL PARAMETER 9

Measurements of Respiration Rate, Temperature, Pulse rate, Blood pressure Measurements-


Direct, Indirect. Blood flow Measurements – In vitro, In vivo, Gas flow measurements. Lung
volume measurement – Spirometer.

UNIT III CARDIAC CARE UNITS 9

Pace makers - different types, batteries for pace makers, Design Concept. DC defibrillators,
asynchronous and synchronous types, patient monitoring system, principles of bio telemetry

UNIT IV ASSIST DEVICES 9

Heart Lung Machine-Condition to be satisfied by the H/L System. Different types of


Oxygenators, Pumps, Pulsatile and Continuous Types, Monitoring Process. Hemodialyser-
Indication and Principle of Hemodialysis, Membrane, Dialysate, Different types of
hemodialysers, Monitoring Systems, Wearable Artificial Kidney, Implanting Type. Respiratory
aids- Types of Ventilators – Pressure, Volume, and Time controlled.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT V DIATHERMY, STIMULATOR AND PATIENT SAFETY 9

Diathermy-Physiological effects of HF radiation, Depth of Penetration, short wave, Ultrasonic


and microwave diathermy, Surgical diathermy, Hazards and safety procedures. Medical
Stimulators – Intensity Duration Curve, Current waveforms - Galvanic, Faradic, surged faradic,
exponential, biphasic, TENS, Interferential therapy. Electrical Safety-Leakage current, Micro and
macro electric shock, GFI units, Earthing Scheme, Electrical safety Analyser.
TOTAL: 45 PERIODS
REFERENCES:
1. L.A Geddes and L.E.Baker, Principles of Applied Biomedical Instrumentation, 3rd Edition, John
Wiley and Sons, Reprint 2008.
2. John G.Webster, Medical Instrumentation Application and Design, 4th Edition, John Wiley and
Sons, New York, 2009.
3. Khandpur R.S, Handbook of Biomedical Instrumentation, Tata McGraw Hill, New Delhi, 3rd
Edition, 2014.
4. Joseph J. Carr and John M. Brown, Introduction to Biomedical equipment technology,
Pearson Education, 4th Edition, 2014.
5. Richard S.Cobbold, Transducers for Biomedical Measurements; Principle and applications-
John Wiley and sons, 1992.
COURSE OUTCOMES

After the completion of the course the student will be able to


CO1. Design and analyze the bioamplifiers.
CO2. Measure vital and non-electrical parameters.
CO3. Design and demonstrate the pacemaker and defibrillator.
CO4. Demonstrate the function of assist devices.
CO5. Design stimulators and test the electrical safety of medical equipment in the hospital
environment.
CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 - 3 3 2 2
2 3 - 3 3 2 2
3 3 - 3 3 2 2
4 3 - 3 3 2 2
5 3 - 3 3 2 2
Low (1); Medium (2); High (3)

BM1232 REHABILITATION ENGINEERING L T P C


3 0 0 3
COURSE OBJECTIVES:

 To learn the basics of rehabilitation engineering.


 To study about principle of rehabilitation engineering
 To understand different types of Therapeutic Exercise Technique.
 To understand the tests to assess the hearing loss and development techniques of electronic
devices for visually and auditory impaired
 To study about various orthopedic devices and prosthetic devices

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT I INTRODUCTION TO REHABILITATION 9

Rehabilitation: Epidemiology of Rehabilitation, Health, Levels of Prevention, Preventive


Rehabilitation, Diagnosis of Disability, Functional Diagnosis, Importance of Psychiatry in
Functional diagnosis, Impairment disability handicap, Primary & secondary Disabilities,
Rehabilitation team Classification of members, The Role of Psychiatrist, Occupational therapist,
Physical therapist, Recreation therapist, Prosthetist - Orthotist, Speech pathologist,
Rehabilitation nurse, Social worker, Corrective therapist, Psychologist, Music therapist, Dance
therapist & Biomedical engineer.

UNIT II PRINCIPLE OF REHABILITATION 9

Introduction, The Human Component, Principles of Assistive Technology Assessment,


Principles of Rehabilitation Engineering- Key Engineering Principles, Key Ergonomic Principles-
Practice of Rehabilitation and Assistive Technology.

UNIT III THERAPEUTIC EXERCISE TECHNIQUE 9

Co-ordination exercises, Frenkels exercises, Gait analyses-Pathological Gaits, Gait Training,


Relaxation exercises-Methods for training Relaxation, Strengthening exercises-Strength training,
Types of Contraction, Mobilisation exercises, Endurance exercises.

UNIT IV MANAGEMENT OF COMMUNICATION & VIRTUAL REALITY 9

Impairment-introduction to communication, Aphasia, Types of aphasia, Treatment of aphasic


patient, Augmentative communication-general form of communication, types of visual aids,
Hearing aids, Types of conventional hearing aid, Writing aids. Introduction to virtual reality,
Virtual reality based rehabilitation, Hand motor recovery systems with Phantom haptics,
Robotics and Virtual Reality Applications in Mobility Rehabilitation.

UNIT V ORTHOTIC, PROSTHETIC DEVICES & RESTORATION TECHNIQUES 9

General orthotics, Classification of orthotics-functional & regional, General principles of


Orthosis, Calipers- FO, AFO, KAFO, HKAFO. Prosthetic devices: Hand and arm replacement, Body
powered prosthetics, Myoelectric controlled prosthetics and Externally powered limb
prosthetics.Functional Electrical Stimulation systems-Restoration of hand function, restoration
of standing and walking, Hybrid Assistive Systems (HAS).
TOTAL: 45 PERIODS
REFERENCES:
1. Rory A Cooper, An Introduction to Rehabilitation Engineering, Taylor & Francis, CRC press,
2006.
2. Susan B O’Sullivan, Thomas J Schmitz, Physical Rehabilitation. 5th Edition, Davis publications,
2007.
3. Joseph D.Bronzino,The Biomedical Engineering Handbook,Third Edition: Three Volume
Set,CRCPress,2006.
4.MacLachlan M. and Gallagher P. Enabling Technologies – Body Image and Body Function,
Churchill Livingstone, 2004.
5. Mann W.C. (ed). Smart Technology for Aging, Disability, and Independence – The State of The
Science, Wiley, New Jersey, 2005.
6. Muzumdar A. Powered Upper Limb Prostheses – Control, Implementation and Clinical
Application.Springer, 2004

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

COURSE OUTCOMES
After the completion of the course the student will be able to
CO1. Explain the fundamentals of rehabilitation and rehabilitation team members.
CO2. Descirbe the key engineering principles of rehabilitation and assistive technology.
CO3. Apply the types of therapeutic exercises to benefit the society.
CO4. Design and apply different types Hearing aids, visual aids and their application in
biomedical field and hence the benefit of the society.
CO5. Explain engineering concepts in Virtual reality based rehabilitation devices.Identify
prosthetic and orthotic devices for restoration of limb function

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 2 1 - 1 1
2 2 2 1 - - 2
3 1 2 1 - - 2
4 2 3 2 3 3 2
5 1 3 2 2 2 2
Low (1); Medium (2); High (3)

BM1233 MEDICAL OPTICS L T P C


3 0 0 3
COURSE OBJECTIVES:
 To understand various optical properties of tissue.
 To gain the knowledge of photonics instruments
 To know the engineering and practical applications of optics related to diagnostics
applications.
 To acquire knowledge about therapeutic and surgical applications of lasers in medical fields
 To gain the knowledge of fiber optic sensors used In medical application

UNIT I OPTICAL PROPERTIES OF THE TISSUES 9

Optical properties of tissue- melanin, bilirubin, tissue and their spectrum, optical characteristics
of constituents of blood – RBC, hemoglobin properties, plasma, oxygenated and deoxygenated
hemoglobin, Laser tissue Interaction-Chemical, Thermal, Electromechanical. Photo ablative
processes. Laser safety procedures.

UNIT II INSTRUMENTATION IN PHOTONICS 9

Reviewof basic properties of light – Reflection, Refraction, Scattering, fluorescence and


phosphorescence. Instrumentation for absorption, scattering and emission measurements.
Optical sources – high pressure arc lamps, LEDs, Medical Lasers. Optical filters. Optical detectors
- Time resolved and phase resolved detectors, optical tweezers.

UNIT III DIAGNOSTIC APPLICATIONS 9

Wood’s lamp, Imaging techniques - Optical coherence tomography, Elastography, Fluorescence


Imaging, Raman Imaging, FLIM, FRAP, NIRS-Application, X-Ray Diagnostic Techniques, Speckle
Correlometry, Near-Field Imaging in Biological and Biomedical Applications, Biopsy.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT IV THERAPEUTIC AND SURGICAL APPLICATIONS OF LIGHT 9

Phototherapy, Photodynamic therapy (PDT) - Principle and mechanism - Oncological and non-
oncological applications of PDT - Biostimulation effect – applications. Laser in tissue welding,
lasers in dermatology, lasers in ophthalmology, otolaryngology, urology, neurology,
orthopedics, gastroenterology.

UNIT V FIBER OPTIC SENSORS AND APPLICATIONS 9

Light transport in the optical fiber - Total internal reflection, Numerical aperture, Angle of
acceptance. losses in fiber, Optical sensors based on polarization, magnetic sensors, Medical
applications of fiber optic sensors in measuring temperature, pressure, flow and chemical
activities, types of optical scopes.

TOTAL: 45 PERIODS
REFERENCES:
1. Mark E. Brezinski, “Optical Coherence Tomography: Principles andApplications”,Academic
Press, 2006.
2. MarkolfH.Niemz, “Laser-Tissue Interaction Fundamentals and Applications”, Springer, 2007.
3. Paras N. Prasad, “Introduction to Biophotonics, A. John Wiley and sons, Inc.
Publications,2003.
4. R. Splinter and B.A. Hooper, “An Introduction to BioMedical Optics”, Taylor and Francis,2007.
5. Tuan Vo Dinh, “Biomedical photonics – Handbook”, CRC Press LLC, 2003.

COURSE OUTCOMES
After the completion of the course the student will be able to
CO1. Understand various optical properties of tissue.
CO2. Describe the photonics instruments.
CO3. Know the diagnostic applications of lasers in medical fields.
CO4. Explain the therapeutic and surgical applications of lasers in medical fields.
CO5. Describe the types of fiber optic sensors used in medical application.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 1 2 1 - -
2 1 1 1 - - 1
3 2 1 2 - - 2
4 2 1 2 1 - 2
5 2 1 2 1 - 2
Low (1); Medium (2); High (3)

BM1234 HUMAN ASSIST DEVICES L T P C


3 0 0 3
COURSE OBJECTIVES:
 To know the principle and design of Heart lung machine and artificial heart.
 To acquire knowledge of various cardiac assist devices
 To study implantation of artificial kidney.
 To understand the principle of prosthetic and orthotic devices for the disability
 To Gain knowledge in respiratory devices and hearing aids

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT I HEART LUNG MACHINE AND ARTIFICIAL HEART 9

Condition to be satisfied by the H/L System. Different types of Oxygenators, Pumps, Pulsatile
and Continuous Types, Monitoring Process, Shunting, The Indication for Cardiac Transplant,
Driving Mechanism, Blood Handling System, Functioning and different types of Artificial Heart,
Mock test setup for assessing its Functions.

UNIT II CARDIAC ASSIST DEVICES 9

Synchronous Counter pulsation, Assisted through Respiration Right Ventricular Bypass Pump,
Left Ventricular Bypass Pump, Open Chest and closed Chest type, Intra Aortic Balloon Pumping
Veno Arterial Pumping, Prosthetic Cardiac Valves, Principle and problem, Biomaterials for
implantable purposes, its characteristics and testing.

UNIT III ARTIFICIAL KIDNEY 9

Indication and Principle of Haemodialysis, Membrane, Dialysate, Different types of


hemodialyzers, Monitoring Systems, Wearable Artificial Kidney, Implanting Type, renal
transplant.

UNIT IV PROSTHETIC AND ORTHOTIC DEVICES 9

Spinal orthotics and Prosthesis, Splint – Static and Dynamic. Hand and Arm Replacement -
Different Types of Models Externally Powered Limb Prosthesis, Intelligent prosthesis, Lower
Limb and Upper limb orthotic devices, Functional Electrical Stimulation, Sensory Assist Devices,
Materials for Prosthetic and orthotic devices, Haptic Devices, Transcutaneous electrical nerve
stimulator.

UNIT V RESPIRATORY AND HEARING AIDS 9

Pulmonary disease diagnosis, Ventilator and its types-Intermittent positive pressure, Breathing
Apparatus Operating Sequence, Electronic IPPB unit with monitoring for all respiratory
parameters. Types of Deafness, Hearing Aids, Construction and Functional Characteristics.

TOTAL: 45 PERIODS
REFERENCES:
1. Andreas.F.Vonracum, Handbook of biomaterial evaluation, Mc-Millan publishers, 1980.
2. Albert M.Cook and Webster J.G., Therapeutic Medical Devices, Prentice Hall Inc.,New
Jersey,1982.
3. Gray E Wnek, Gray L Browlin – Encyclopedia of Biomaterials and Biomedical Engineering –
Marcel Dekker Inc New York 2004.
4. John. G . Webster – Bioinstrumentation - John Wiley & Sons (Asia) Pvt Ltd - 2008.
5. Kolff W.J., Artificial Organs, John Wiley and Sons, New York, 1979.
6. Gerr . M. Craddock “Assistive Technology-Shaping the future”, IOS Press, 1st edition, 2003

COURSE OUTCOMES
After the completion of the course the student will be able to
CO1. Knowledge about the importance of Heart lung machine and artificial Heart.
CO2. Knowledge about the importance of different types of assist devices and related issues.
CO3. Understand about the implantation of artificial kidney.
CO4. Explore the different types of models for Prosthetic and orthotic purpose.
CO5. Perceive the knowledge in different types of respiratory and hearing aids.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 - 1 1 3 2
2 1 - 1 1 3 1
3 1 - 1 1 3 1
4 1 - 2 1 2 3
5 1 - 2 2 1 3
Low (1); Medium (2); High (3)
BM1235 MEDICAL DEVICE STANDARDS AND REGULATION
L T P C
3 0 0 3
COURSE OBJECTIVES:
 Understand standards and safety aspects of medical devices.
 Understand the hospital safety standards and maintenance
 Describe medical device regulations.
 Describe medical device regulations
 Describe medical device risk assessment and regulatory requirements
UNIT I STANDRADS AND SAFETY 9

Quality management system for medical devices (ISO 9001 and ISO13485), safety and
standardization for risk management (ISO 14971), European standard conformity (CE marking),
FDA guidelines for medical devices approval and classification based on risk assessment.

UNIT II HOSPITAL SAFETY STANDARDS 9

Life Safety Standards- Protecting Occupants, Protecting the Hospital From Fire, Smoke, and
Heat, Protecting Individuals From Fire and Smoke, Providing and Maintaining Fire Alarm
Systems, Systems for Extinguishing Fires Environment of Care Standards-Minimizing EC Risks,
Smoking Prohibitions, Managing Hazardous Material and Waste, Maintaining Fire Safety
Equipment, Features, Testing, Maintaining, and Inspecting Medical Equipment

UNIT III MEDICAL EQUIPMENT ESSENTIAL REQUIREMENTS 9

General requirements for basic safety & essential performance of medical equipment, IEC
60601 standards- Base Standard-general requirement of electrical medical devices, Collateral
Standards- EMC radiation protection &programmable medical device system, Particular
Standards-type of medical device.

UNIT IV MEDICAL DEVICE REGULATION 9

Medical device and in vitro diagnostics: Introduction & types of devices including combination
devices. Medical Device Rules, 2017: Implications on medical devices. Classification of medical
devices. Labelling of medical devices and in vitro diagnostics.

UNIT V MEDICAL DEVICE RISK ASSESSMENT 9

Inspection of medical device and IVD establishments. ISO 14971 (Medical devices: Application
of risk management to medical devices). Regulatory requirements of biocompatibility of
medical devices and ISO 10993. Clinical investigation of medical devices, regulation of
investigational medical devices. Medical device regulation: International practices.
TOTAL: 45 PERIODS

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

REFERENCES:
1. Seeram Ramakrishna, Lingling Tian, Charlene Wang, Susan Liao, Wee EongTeo, Medical
Devices Regulations, Standards and Practice, Wood head Publishing, 1st Edition, 2015.
2. Joint Commission International Accreditation Standards for Hospitals, Joint Commission
International, 6th Edition, 2017.
3. Joseph D. Nally (ed.), Good Manufacturing Practices for Pharmaceuticals ,CRC Press sixth
edition, 2007.
4. https://nptel.ac.in/courses/127106136.
5. MDR17, Regulation of Medical Devices.

COURSE OUTCOMES
After the completion of the course the student will be able to
CO1. Describe the key point in standard and safety of medical devices.
CO2. Introduce the students with the knowledge of hospital safety and standards.
CO3. Introduce the students with the knowledge of essential requirements in medical
equipments.
CO4. Introduce device regulation and its types.
CO5. Acquire knowledge medical device risk assessment.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 2 1 - 1 -
2 1 2 1 - 1 -
3 1 2 1 - 1 -
4 1 2 1 - 1 -
5 1 2 1 - 1 -
Low (1); Medium (2); High (3)

BM1236 NUCLEAR MEDICINE L T P C


3 0 0 3
COURSE OBJECTIVES:

 To understand the basic physics of various imaging modalities in nuclear medicine.


 To gain knowledge about various detectors used in nuclear medicine
 To gain knowledge in maintenance, handling and operation of the various equipments in this
field.
 To understand the basic working principle of Emission Tomography
UNIT I BASIC PHYSICS BEHIND RADIOACTIVITY 9

Physics of Radioactivity: Radionuclide Decay Terms and Relationships – Activity – Physical half
Life – Fundamental Decay Equation, Nuclear Transformation – Alpha Decay, Beta-Minus Decay-
Beta Plus – Electron Capture – Isomeric Transition – Decay Schemes.

UNIT II PRODUCTION OF RADIOACTIVE ELEMENTS 9

Radionuclide Production: By cyclotron, nuclear reactor, neutron activation method, and


generators, Radiopharmaceuticals – Characteristics, applications, quality control and regulatory
issues in medical imaging, Radiopharmaceutical mechanisms of localization

35
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT III RADIOACTIVITY DETECTORS 9

Radionuclide detection and measurement - Type of detectors – pulsed and current mode -
spectroscopy, Gas Filled detectors, Scintillation detectors, Semiconductor detectors, Pulse
height spectroscopy, Non– imaging detector applications, Counting Statistics.

UNIT IV NUCLEAR IMAGING 9

Planar Nuclear Imaging: Anger Scintillation Camera – Design and principles of operation-
performance – design factors, Computers in Nuclear Imaging – Digital image formats – image
acquisition – Image processing in nuclear medicine.

UNIT V EMISSION TOMOGRAPHY AND APPLICATIONS 9

Nuclear Imaging Emission Tomography: Focal plane tomography - Single photon emission
computed tomography (SPECT) – image acquisition – Image reconstruction – attenuation
correction in SPECT, Positron emission tomography – Design and principles of operation – 2-D
and 3-D acquisition – Comparison of SPECT and PET – Combines X-ray CT and SPECT –
Applications: Whole body, Heart and Brain.
TOTAL: 45 PERIODS
REFERENCES:

1. Jerrold T Bushberg, J.Anthony Seibert, Edwin M Leidholdt,John M Boone, Lippincott, “The


Essential Physics of Medical Imaging” Williams & Wilkins,3rd edition,2011.
2. S Webb, “The Physics of Medical Imaging”, Adam Highler, Bristol Published by CRC Press, first
edition 1988.
3. Webb’s, “Physics of Medical Imaging”, Taylor and Francis Group”, CRC Press,2nd edition,
2012.
4. R. S. Khandpur “Handbook of Bio-Medical Instrumentation”, Tata McGraw Hill, 2nd edition,
2003.

COURSE OUTCOMES

After the completion of the course the student will be able to

CO1. Describe the physics behind radiation.


CO2. Introduce students with the knowledge on radioactive elements.
CO3. Introduce the students with the knowledge of radioactive detectors.
CO4. To understand nuclear imaging.
CO5. Acquire knowledge on emission tomography and its applications.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 1 2 2 - 2
2 2 2 1 2 - 1
3 3 2 2 3 2
4 1 1 2 2 1 1
5 3 1 2 2 2 2
Low (1); Medium (2); High (3)

36
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1241 TELEHEALTH TECHNOLOGY L T P C


3 0 0 3
COURSE OBJECTIVES:

 To teach the key principles for telemedicine and health.


 To make student understand telemedical technology
 To introduce the students with the knowledge of telemedical standards
 To design and develop m-Health platforms for telemedical applications and diagnosis
 To make student understand the applications of health care sectors

UNIT I TELEMEDICINE AND HEALTH 9

History and Evolution of telemedicine, Functional diagram of telemedicine system,


Telemedicine, Tele health, Tele care, Organs of telemedicine, Global and Indian scenario,
International regulations in e-health and telemedicine, Ethical and legal aspects of Telemedicine
- Confidentiality, Social and legal issues, Safety and regulatory issues, Advances in Telemedicine.

UNIT II TELEMEDICAL TECHNOLOGY 9

Principles of Multimedia - Text, Audio, Video, data, Data communications and networks, PSTN,
POTS, ANT, ISDN, Internet, Air/ wireless communications: GSM satellite, and Micro wave,
Modulation techniques, Types of Antenna, Integration and operational issues, Communication
infrastructure for telemedicine – LAN and WAN technology. Satellite communication. Mobile
hand held devices and mobile communication. Internet technology and telemedicine using
world wide web (www). Video and audio conferencing. Clinical data –local and centralized

UNIT III TELEMEDICAL TECHNOLOGY 9

Data Security and Standards: Encryption, Cryptography, Mechanisms of encryption, phases of


Encryption. Protocols: TCP/IP, ISO-OSI, Standards to followed DICOM, HL7, H. 320 series
(Videophone based ISBN) T. 120, H.324 (Video phone based PSTN), Video Conferencing, Real
time Telemedicine integrating doctors / Hospitals, Clinical laboratory data, Radiological data,
and other clinically significant biomedical data, Administration of centralized medical data,
security and confidentially of medical records and access control, Cyber laws related to
telemedicine.

UNIT IV m-HEALTH AND TELEMEDICINE 9

Mobile Devices : Smart phones, Tablet PCs, iPads, PDAs, Wearable computers – m-Health
technology and communication infrastructure - Healthcare Apps – m-Health applications:
Education and awareness, Remote data collection, Remote monitoring, Communication and
training for healthcare workers, Disease and epidemic outbreak tracking, Diagnostic and
treatment support – m-Health and the Transformation of Clinical Trials - Harnessing data,
advanced analytics, and the Internet of Things to optimize digitized clinical trials.

UNIT V TELEMEDICAL APPLICATIONS 9

Telemedicine access to health care services – health education and self-care. · Introduction to
robotics surgery, telesurgery. Telecardiology, Teleoncology, Telemedicine in neurosciences,
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

Electronic Documentation, e-health services security and interoperability., Telemedicine access


to health care services– health education and self-care, Business aspects - Project planning and
costing, Usage of telemedicine. Telemedicine and in loco assistance of patients, Interactive
videoconferencing consults, Store and forward consults, Remote monitoring and home care.

TOTAL: 45 PERIODS
REFERENCES:
1. Wootton, R., Craig, J., Patterson, V. (Eds.), Introduction to Telemedicine. Royal Society of
Medicine Press Ltd (ISBN 1853156779), 2006.
2. Teresa L. Thompson, Roxanne Parrott, Jon F. Nussbaum, TheRoutledge Handbook of Health
Communication, Routledge, 2011.
3. David Dagan Feng, Biomedical Information Technology, Academic Press Series in Biomedical
Engineering, Elsevier Inc, USA, 2008
4. Ilias G. Maglogiannis, Kostas Karpouzis and Manolis Wallace, Image and Signal Processing for
Networked E-Health Applications, Morgan & Claypool Publishers’ series, USA, 2006.
5. Tuan Bernard Fong, A.C.M. Fong, C.K. Li, Telemedicine Technologies: Information
Technologies in Medicine and Telehealth, Wiley, 2011.
6. Bemmel, J.H. van, Musen, M.A. (Eds.) (1997). Handbook of Medical Informatics. Heidelberg,
Germany: Springer. (ISBN 3-540-63351-0).
7. Ferrer-Roca, O., Sosa-Iudicissa, M. (editors), Handbook of Telemedicine. IOS Press (Studies in
Health Technology and Informatics, Volume 54). (ISBN 90-5199-413-3), 2002.
8. Magnuson, J.A., Fu, Jr., Paul C. (Eds.), Public Health Informatics and Information systems,
ISBN 978-1-4471-4237-9, Springer, 2014
9. Simpson, W. 2006. Video over IP. A practical guide to technology and applications. Focal
Press (Elsevier). ISBN-10: 0-240-80557-7.

COURSE OUTCOMES
After the completion of the course the student will be able to
CO1. Describe the key principles for telemedicine and health
CO2. Understand telemedical technology
CO3. Know Introduce the students with the knowledge of telemedical standards.
CO4. Design and develop m-Health platforms for telemedical applications
CO5. Acquire knowledge of evaluating the force in implants.
CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 2 1 - - - -
2 1 1 1 - - -
3 1 1 - - - -
4 2 2 2 3 3 3
5 2 2 2 1 2 3
Low (1); Medium (2); High (3)

BM1242 MEDICAL ROBOTICS L T P C


3 0 0 3
COURSE OBJECTIVES:
 To explain the basic concepts of robots and types of robots
 To discuss the designing procedure of manipulators, actuators and grippers
 To impart knowledge on various types of sensors and power sources
 To explore various applications of Robots in Medicine
 To impart knowledge on wearable robots

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT I INTRODUCTION TO ROBOTICS 9

Introduction to Robotics, Overview of robot subsystems, Degrees of freedom, configurations


and concept of workspace, Dynamic Stabilization
Sensors and Actuators
Sensors and controllers, Internal and external sensors, position, velocity and acceleration
sensors, Proximity sensors, force sensors Pneumatic and hydraulic actuators, Stepper motor
control circuits, End effectors, Various types of Grippers, PD and PID feedback actuator models.

UNIT II MANIPULATORS & BASIC KINEMATICS 9

Construction of Manipulators, Manipulator Dynamic and Force Control, Electronic and


pneumatic manipulator, Forward Kinematic Problems, Inverse Kinematic Problems, Solutions
of Inverse Kinematic problems

Navigation and Treatment Planning

Variable speed arrangements, Path determination – Machinery vision, Ranging – Laser –


Acoustic, Magnetic, fiber optic and Tactile sensor

UNIT III SURGICAL ROBOTS 9

Da Vinci Surgical System, Image guided robotic systems for focal ultrasound based surgical
applications, System concept for robotic Tele-surgical system for off-pump, CABG surgery,
Urologic applications, Cardiac surgery, Neuro-surgery, Pediatric and General Surgery,
Gynecologic Surgery, General Surgery and Nanorobotics. Case Study

UNIT IV REHABILITATION AND ASSISTIVE ROBOTS 9

Pediatric Rehabilitation, Robotic Therapy for the Upper Extremity and Walking, Clinical-Based
Gait Rehabilitation Robots, Motion Correlation and Tracking, Motion Prediction, Motion
Replication. Portable Robot for Tele rehabilitation, Robotic Exoskeletons – Design
considerations, Hybrid assistive limb, cobots. Case Study

UNIT V WEARABLE ROBOTS 9

Augmented Reality, Kinematics and Dynamics for Wearable Robots, Wearable Robot
technology, Sensors, Actuators, Portable Energy Storage, Human–robot cognitive interaction
(cHRI), Human–robot physical interaction (pHRI), Wearable Robotic Communication - case
study
TOTAL: 45 PERIODS
REFERENCES:
1. Nagrath and Mittal, “Robotics and Control”, Tata McGraw Hill, First edition, 2003
2. Spong and Vidhyasagar, “Robot Dynamics and Control”, John Wiley and Sons, First
edition, 2008
3. Fu.K.S, Gonzalez. R.C., Lee, C.S.G, “Robotics, control”, sensing, Vision and Intelligence, Tata
McGraw Hill International, First edition, 2008
4. Bruno Siciliano, OussamaKhatib, Springer Handbook of Robotics, 1st Edition, Springer,2008
5. Shane (S.Q.) Xie, Advanced Robotics for Medical Rehabilitation - Current State of the Art
and Recent Advances, Springer, 2016

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6. Sashi S Kommu, Rehabilitation Robotics, I-Tech Education and Publishing, 2007


7. Jose L. Pons, Wearable Robots: Biomechatronic Exoskeletons, John Wiley & Sons Ltd,
England,2008
8. Howie Choset, Kevin Lynch, Seth Hutchinson, “Principles of Robot Motion: Theory,
Algorithmsand Implementations”, Prentice Hall of India, First edition, 2005
9. Philippe Coiffet, Michel Chirouze, “An Introduction to Robot Technology”, Tata McGraw
Hill, First Edition, 1983
10. Jacob Rosen, Blake Hannaford & Richard M Satava, “Surgical Robotics: System
Applications &Visions”, Springer 2011
11. Jocelyn Troccaz, Medical Robotics, Wiley, 2012
12. AchimSchweikard, Floris Ernst, Medical Robotics, Springer, 2015

COURSE OUTCOMES

After the completion of the course the student will be able to


CO1. Describe the configuration, applications of robots and the concept of grippers and
actuators
CO2. Explain the functions of manipulators and basic kinematics
CO3. Describe the application of robots in various surgeries
CO4. Design and analyze the robotic systems for rehabilitation
CO5. Design the wearable robots

CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 - - - 1 - -
2 - - - 2 - -
3 2 - 2 2 2 2
4 2 - 2 2 3 2
5 2 - 2 2 3 3
Low (1); Medium (2); High (3)

BM1243 WEARABLE TECHNOLOGY L T P C


3 0 0 3
COURSE OBJECTIVES:

 Identify the motivation, guiding principles, and challenges of Wearable Computing.


 Develop skills pertaining to the design of a holistic interactive wearable system comprising of
the physical, digital, and the human aspects
 To provide the basic understanding of measurement and instrumentation systems and the
insight of the resistive sensors and its applications in real life..
 To introduce the concept of the reactive sensors and self-generating sensors and its
applications in real life
 To impart the importance of smart sensors, sensor interface standards for wearable device
applications and to provide a brief overview of the wearable technology and its impact on
social life

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UNIT I INTRODUCTION 9

Attributes of wearables, Meta-wearable, Challenges and opportunities, Future of wearables -


Social aspects of wearability and interaction: Social interpretation of Aesthetics - Case study:
Google glass - Wearable haptics: Need for wearable haptic devices - Categories of wearable
haptic and tactile display – Wearable sensorimotor enhancer.

UNIT II WEARABLE SENSORS 9

Chemical and Biochemical sensors, System design, Challenges in chemical Bio-chemical sensing,
Application areas - Inertia sensors, Parameters from inertia sensors - Applications for wearable
motion sensors - Measurement of energy expenditure by body worn heat flow sensors.

UNIT III FLEXIBLE ELECTRONICS 9

Introduction, Thin-film transistors: Materials and Technologies, Review ofSemi-conductors in


flexible electronics - Low-power Integrated Circuit Design for Bio-potential sensing: Analog
circuit design techniques - Low- power design for ADCs - Digital circuit design techniques -
Architectural design for low-power bio-potential acquisition, Practical considerations.

UNIT IV ENERGY HARVESTING SYSTEMS 9

Energy harvesting from human body: Temperature gradient, Foot motion - Wireless energy
transmission - Energy harvesting from light and RF energy - Energy and power consumption
issues, Future considerations.

UNIT V MONITORING PHYSICAL AND PHYSIOLOGICAL PARAMETERS 9

Wearable sensors for physiological signal measurement - Physical measurement: Cardiovascular


diseases, Neurological diseases, Gastrointestinal diseases - Wearable and non-invasive assistive
technologies: Assistive devices for individuals with severe paralysis, Wearable tongue drive
system, Sensor signal-processing algorithm, Dual-mode tongue drive system.

TOTAL: 45 PERIODS
REFERENCES:
1. Edward Sazonov, Michael R Neuman, "Wearable Sensors: Fundamentals, Implementation
and Applications", Academic Press, USA, 2014.
2. Tom Bruno , "Wearable Technology: Smart Watches to Google Glass for Libraries",
Rowman & Littlefield Publishers, Lanham, Maryland, 2015.
3. Raymond Tong , "Wearable Technology in Medicine and Health Care", Academic Press,
USA, 2018.
4. HaiderRaad , "The Wearable Technology Handbook", United Scholars Publication, USA,
2017.
COURSE OUTCOMES

After the completion of the course the student will be able to


CO1. Understand the fundamentals of wearables, wearable design issues and user interfaces
CO2. Identify the different types of sensors used in wearable devices
CO3. Recognize the materials used in the field of flexible electronics technology and its power
constraints

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CO4. Summarize the techniques and issues associated with energy harvesting from human
body
CO5. Elucidate the applications of wearable technology in health care

CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 - 1 2 2 - 2
2 3 2 2 2 - 1
3 3 2 2 1 - 2
4 1 1 2 1 1 2
5 3 1 2 2 - 2
Low (1); Medium (2); High (3)

BM1244 MEDICAL ETHICS AND STANDARDS L T P C


3 0 0 3
COURSE OBJECTIVES:

 Achieve familiarity with some basic ethical frameworks & understand how these ethical
frameworks can help us to think through contemporary questions in medical ethics.
 Students will be able to know about the legal and ethical principles
 To apply these principles in health care settings & gain knowledge about the medical
standards that are to be followed in hospitals.

UNIT I INTRODUCTION TO MEDICAL ETHICS 9

Definition of Medical ethics, Scope of ethics in medicine, American Medical Association code of
ethics, CMA code of ethics- Fundamental Responsibilities, The Doctor and The Patient, The
Doctor and The Profession, Professional Independence, The Doctor and Society.

UNIT II ETHICAL THEORIES & MORAL PRINCIPLES 9

Theories-Deontology & Utilitarianism, Casuist theory, Virtue theory, The Right Theory.
Principles-Non- Maleficence, Beneficence, Autonomy, Veracity, Justice. Autonomy &
Confidentiality issues in medical practice, Ethical Issues in biomedical research, Bioethical issues
in Human Genetics & Reproductive Medicine

UNIT III HOSPITAL ACCREDITATION STANDARDS 9

Accreditation- JCI Accreditation &its Policies. Patient Organization management standards.

UNIT IV HOSPITAL SAFETY STANDARDS 9

Life Safety Standards- Protecting Occupants, Protecting the Hospital from Fire, Smoke, and
Heat, Protecting Individuals from Fire and Smoke, Providing and Maintaining Fire Alarm
Systems, Systems for Extinguishing Fires Environment of Care Standards-Minimizing EC Risks,
Smoking Prohibitions, Managing Hazardous Material and Waste, Maintaining Fire Safety
Equipment, Features, Testing, Maintaining, and Inspecting Medical Equipment.

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UNIT V MEDICAL EQUIPMENT SAFETY STANDARDS 9

General requirements for basic safety & essential performance of medical equipment. IEC
60601 standards, Indian and International standards, ISO standards - Base Standard-general
requirement of electrical medical devices, Collateral Standards- EMC radiation protection
&programmable medical device system, Particular Standards-type of medical device.

TOTAL: 45 PERIODS

REFERENCES:
1. Domiel A Vallero, Biomedical Ethics for Engineers, Elsevier Pub.1st edition, 2007
2. Johnna Fisher, Biomedical Ethics: A Canadian Focus., Oxford University Press Canada, 2009.
3. Robert M Veatch, The Basics of Bio Ethics, 3rd Edition. Routledge, 2011.
4. Physical Environment Online: A Guide to The Joint Commission’s Safety Standards is
published by HCPro, Inc. 2010
5. Joint Commission Accreditation Standards for Hospitals, 6th Edition 2018.
6. Ben Mepham, Bioethics-An Introduction for the biosciences, 2nd Edition,
Oxford University Press, 2008.
7. Nils Hoppe and Jose Miola - Medical law and Medical Ethics - Cambridge University Press-
2014
COURSE OUTCOMES

After the completion of the course the student will be able to


CO1. Describe the Social responsibility in healthcare systems
CO2. Discuss the Bioethics and engineers role
CO3. Apply Legal and professional guidelines for the hospital accreditation
CO4. Understand hospital safety aspects
CO5. Comprehend the medical equipment safety standards and medical device maintenance.

CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 1 1 2 - 2 2
2 1 1 2 - 1 1
3 - 1 1 - - 1
4 - 1 1 - - 1
5 - - 1 - 2 2
Low (1); Medium (2); High (3)

BM1245 BRAIN COMPUTER INTERFACE


L T P C
COURSE OBJECTIVES: 3 0 0 3

The objective of this course is to enable the student to

 Understand the basic concepts of brain computer interface.


 Understand the basic concepts of brain computer interface
 Understand the signal processing methods used in BCI
 To design and develop m-Health platforms for telemedical applications and diagnosis
 Learn the various applications of BCI

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UNIT I INTRODUCTION TO BCI 9

Introduction - Brain structure and function, Brain Computer Interface Types - Synchronous and
Asynchronous -Invasive BCI -Partially Invasive BCI - Non Invasive BCI, Structure of BCI System,
BCI Monitoring Hardware, EEG, MEG, fMRI.

UNIT II BRAIN ACTIVATION 9

Brain activation patterns - Oscillatory potential and ERD, Slow cortical potentials, Movement
related potentials-Mu rhythms, motor imagery, Stimulus related potentials – Visual Evoked
Potentials – P300 and Auditory Evoked Potentials

UNIT III FEATURE EXTRACTION METHODS 9

Data Processing – Spike sorting, Frequency domain analysis, Wavelet analysis, Time domain
analysis, Spatial filtering -Principal Component Analysis (PCA), Independent Component Analysis
(ICA), Artefacts reduction, Feature Extraction - Phase synchronization.

UNIT IV MACHINE LEARNING METHODS FOR BCI 9

Classification techniques –Binary classification, Multiclass Classification, Evaluation of


classification performance, Regression - Linear, Polynomial, RBF’s, Support vector machine,
Graph theoretical functional connectivity analysis.

UNIT V APPLICATIONS OF BCI 9

Case Studies - Invasive BCIs: decoding and tracking arm (hand) position, controlling prosthetic
devices such as orthotic hands, Cursor and robotic control using multi electrode array implant,
Cortical control of muscles via functional electrical stimulation. Ethics of Brain Computer
Interfacing.
TOTAL: 45 PERIODS

REFERENCES

1. Rajesh P.N. Rao, Brain-Computer Interfacing: An Introduction, Cambridge University Press,


1st Edition, 2013.
2. Ella Hassianien A and Azar A.T Ed, Brain-Computer Interfaces Current Trends an Applications,
Springer, 2015.
3. Jonathan Wolpaw and Elizabeth Winter Wolpaw, Brain Computer Interfaces: Principles and
practice, Oxford University Press, USA, 1stEdition, 2012
4. Bernhard Graimann, Brendan Allison and GertPfurtscheller, Brain-Computer Interfaces:
Revolutionizing Human-Computer Interaction, Springer, 2010.
5. Ali Bashashati, MehrdadFatourechi, Rabab K Ward and Gary E Birch, A survey of signal
Processing algorithms in brain–computer interfaces based on electrical brain signals, Journal
of Neural Engineering, Vol.4, 2007, pp.32-57.
6. Arnon Kohen, Biomedical Signal Processing, Vol I and II, CRC Press Inc, Boca Rato, Florida.
7. Bishop C.M., Neural networks for Pattern Recognition, Oxford, Clarendon Press, 1995.
8. Andrew Webb, Statistical Pattern Recognition, Wiley International, 2nd Edition, 2002

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COURSE OUTCOMES

After the completion of the course the student will be able to


CO1. Evaluate concept of BCI
CO2. Describe the different brain activation signals
CO3. Select appropriate feature extraction methods.
CO4. Use machine learning algorithms for translation
CO5. Develop high-fidelity BCI prototypes.

CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 1 1 2 - 2 2
2 1 1 2 - 1 1
3 - 1 1 - - 1
4 - 1 1 - - 1
5 - - 1 - 2 2
Low (1); Medium (2); High (3)

BM1246 BIOMEDICAL MICRO DEVICES


L T P C
COURSE OBJECTIVES: 3 0 0 3

The objective of this course is to enable the student to

 To understand the working principle of MEMS & microsystems.


 To get an idea about what all materials are used in MEMS & Microsystems
 To understand the working of MOEMS Technology
 To give an insight to the microfluidic systems & biomedical Microsystems
 To understand the concepts of BioMEMS & its application in healthcare
UNIT I INTRODUCTION TO MEMS & MICROSYSTEM 9

MEMS and Microsystems- Introduction - Typical MEMS and microsystem products - Application
of microsystem in healthcare industry - Working principles of microsystems- Microsensors
(Acoustic wave sensor, Biomedical sensor & biosensor, Chemical sensor, Optical sensor,
Pressure sensor, Thermal sensor) – MicroActuation – MEMS with MicroActuation – Micro-
accelerators & Micro-fluidics.

UNIT II MATERIALS FOR MEMS & MICROSYSTEMS 9

Introduction, Substrates & Wafers, Active Substrate Materials, Silicon as a Substrate Material,
Silicon Compounds, Silicon Piezoresistors, Gallium Arsenide, Quartz, Piezoelectric Crystals,
Polymers, Packaging Materials, Microsystem Fabrication Processes (Elementary idea)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT III MICRO-OPTO ELECTRO-MECHANICAL SYSTEM (MOEMS) 9

Fundamental principle of MOEMS technology - Light modulators, Beam splitter – Micro-lens,


Micro-mirrors - Digital micro-mirror device, Light detectors, GLV, Optical Switch, Waveguide &
Tuning, Shear-stress measurement.

UNIT IV MICROFLUIDIC SYSTEMS & BIOMEDICAL MICROSYSTEMS 9

Important consideration on micro-scale fluid, Properties of fluid - Fluid actuation methods –


Micro-pumps - Typical Micro-fluidic channel, Microfluid Dispenser, Sensing Mechanisms in
BCMSSD, Chem- Lab-on-a-Chip, E-Nose, DNA sensors, SAW sensors

UNIT V BIOMEMS 9

Introduction to BioMEMS, BioMEMS for Clinical Monitoring - Multi-parameter monitoring -


Drug delivery, micro total analysis systems (MicroTAS) detection and measurement methods,
Microsystem approaches to polymerase chain reaction (PCR).
TOTAL: 45 PERIODS
REFERENCES:
1. Tai-Ran Hsu, ‘MEMS & MICROSYSTEMS- Design,Manufacture and Nanoscale Engineering’,
John Wiley & Sons, 2nd Edition 2008.
2. NitaigourPremchandMahalik, ‘MEMS’, Tata McGraw Hill, 2nd Reprint 2008.
3. Wanjun Wang & Steven A.Soper , ‘BioMEMS- Technologies and applications’, CRC Press, 2007
4. Steven S. Saliterman, ‘Fundamentals of BioMEMS & Medical Microdevices’, International
Society for Optical Engineering, 2006.
5. Gerald A Urban, ‘BioMEMS’, Springer, 2006.
6. Abraham P. Lee and James L. Lee, ‘BioMEMS and Biomedical Nanotechnology’, Volume I,
Springer, 2006.
7. Paul C.H. Li, ‘Introduction to Microfluids and BioMEMS: A Design and Problem-Solving
Textbook’, CRC Press, 2009.
COURSE OUTCOMES

After the completion of the course the student will be able to

CO1. Evaluate concept of MEMs


CO2. Describe the different materials used in microsystem
CO3. To understand MOEMs.
CO4. Develop MEMs microsystem
CO5. Applications of BioMEMs.

CO Pos
PO1 PO2 PO3 PO4 PO5 PO6
1 1 1 2 - 2 2
2 1 1 2 - 1 1
3 - 1 1 - - 1
4 - 1 1 - - 1
5 - - 1 - 2 2
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

AUDIT COURSES
AC1A61 ENGLISH FOR RESEARCH PAPER WRITING LTPC
2000
COURSE OBJECTIVES:
Teach how to improve writing skills and level of readability
 Tell about what to write in each section
 Summarize the skills needed when writing a Title
 Infer the skills needed when writing the Conclusion
 Ensure the quality of paper at very first-time submission

UNIT I INTRODUCTION TO RESEARCH PAPER WRITING 6

Planning and Preparation, Word Order, Breaking up long sentences, Structuring Paragraphs and
Sentences, Being Concise and Removing Redundancy, Avoiding Ambiguity and Vagueness

UNIT II PRESENTATION SKILLS 6


Clarifying Who Did What, Highlighting Your Findings, Hedging and Criticizing, Paraphrasing and
Plagiarism, Sections of a Paper, Abstracts, Introduction

UNIT III TITLE WRITING SKILLS 6

Key skills are needed when writing a Title, key skills are needed when writing an Abstract, key
skills are needed when writing an Introduction, skills needed when writing a Review of the
Literature, Methods, Results, Discussion, Conclusions, The Final Check

UNIT IV RESULT WRITING SKILLS 6

Skills are needed when writing the Methods, skills needed when writing the Results, skills are
needed when writing the Discussion, skills are needed when writing the Conclusions

UNIT V VERIFICATION SKILLS 6

Useful phrases, checking Plagiarism, how to ensure paper is as good as it could possibly be the
first- time submission
TOTAL: 30 PERIODS
REFERENCES:

1. Adrian Wallwork , English for Writing Research Papers, Springer New York Dordrecht
Heidelberg London, 2011
2. Day R How to Write and Publish a Scientific Paper, Cambridge University Press 2006
3. Goldbort R Writing for Science, Yale University Press (available on Google Books) 2006
4. Highman N, Handbook of Writing for the Mathematical Sciences, SIAM. Highman’s book 1998.

COURSE OUTCOMES:

CO1 : Understand that how to improve your writing skills and level of readability
CO2 : Learn about what to write in each section
CO3 : Understand the skills needed when writing a Title
CO4 : Understand the skills needed when writing the Conclusion
CO5 : Ensure the good quality of paper at very first-time submission

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

AC1A62 DISASTER MANAGEMENT LTPC


2000
COURSE OBJECTIVES:
 Summarize basics of disaster
 Explain a critical understanding of key concepts in disaster risk reduction and humanitarian
response.
 Illustrate disaster risk reduction and humanitarian response policy and practice from multiple
perspectives.
 Describe an understanding of standards of humanitarian response and practical relevance in
specific types of disasters and conflict situations.
 Develop the strengths and weaknesses of disaster management approaches

UNIT I INTRODUCTION 6

Disaster: Definition, Factors and Significance; Difference between Hazard And Disaster; Natural and
Manmade Disasters: Difference, Nature, Types and Magnitude.

UNIT II REPERCUSSIONS OF DISASTERS AND HAZARDS 6

Economic Damage, Loss of Human and Animal Life, Destruction Of Ecosystem. Natural Disasters:
Earthquakes, Volcanisms, Cyclones, Tsunamis, Floods, Droughts And Famines, Landslides And
Avalanches, Man-made disaster: Nuclear Reactor Meltdown, Industrial Accidents, Oil Slicks And Spills,
Outbreaks Of Disease And Epidemics, War And Conflicts.

UNIT III DISASTER PRONE AREAS IN INDIA 6

Study of Seismic Zones; Areas Prone To Floods and Droughts, Landslides And Avalanches; Areas Prone
To Cyclonic and Coastal Hazards with Special Reference To Tsunami; Post-Disaster Diseases and
Epidemics

UNIT IV DISASTER PREPAREDNESS AND MANAGEMENT 6

Preparedness: Monitoring Of Phenomena Triggering a Disaster or Hazard; Evaluation of Risk:


Application of Remote Sensing, Data from Meteorological And Other Agencies, Media Reports:
Governmental and Community Preparedness.

UNIT V RISK ASSESSMENT 6

Disaster Risk: Concept and Elements, Disaster Risk Reduction, Global and National Disaster Risk
Situation. Techniques of Risk Assessment, Global Co-Operation in Risk Assessment and Warning,
People’s Participation in Risk Assessment. Strategies for Survival

TOTAL : 30 PERIODS
REFERENCES:

1. Goel S. L., Disaster Administration And Management Text And Case Studies”,Deep & Deep
Publication Pvt. Ltd., New Delhi,2009.
2. NishithaRai, Singh AK, “Disaster Management in India: Perspectives, issues and strategies
“NewRoyal book Company,2007.
3. Sahni, PardeepEt.Al. ,” Disaster Mitigation Experiences And Reflections”, Prentice Hall Of
India, New Delhi,2001.
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

COURSE OUTCOMES:

CO1: Ability to summarize basics of disaster


CO2: Ability to explain a critical understanding of key concepts in disaster risk reduction and
humanitarian response.
CO3: Ability to illustrate disaster risk reduction and humanitarian response policy and practice
from multiple perspectives.
CO4: Ability to describe an understanding of standards of humanitarian response and practical
relevance in specific types of disasters and conflict situations.
CO5: Ability to develop the strengths and weaknesses of disaster management approaches

AC1A63 CONSTITUTION OF INDIA LTPC


2000
COURSE OBJECTIVES:
Students will be able to:
 Understand the premises informing the twin themes of liberty and freedom from a civil rights
perspective.
 To address the growth of Indian opinion regarding modern Indian intellectuals’ constitutional
 Role and entitlement to civil and economic rights as well as the emergence nation hood in the
early years of Indian nationalism.
 To address the role of socialism in India after the commencement of the Bolshevik Revolutionin
1917 and its impact on the initial drafting of the Indian Constitution.

UNIT I HISTORY OF MAKING OF THE INDIAN CONSTITUTION 5

History, Drafting Committee, (Composition & Working)

UNIT II PHILOSOPHY OF THE INDIAN CONSTITUTION 5

Preamble, Salient Features

UNIT III CONTOURS OF CONSTITUTIONAL RIGHTS AND DUTIES 5

Fundamental Rights, Right to Equality, Right to Freedom, Right against Exploitation, Right to Freedom
of Religion, Cultural and Educational Rights, Right to Constitutional Remedies, Directive Principles of
State Policy, Fundamental Duties.

UNIT IV ORGANS OF GOVERNANCE 5

Parliament, Composition, Qualifications and Disqualifications, Powers and Functions, Executive,


President, Governor, Council of Ministers, Judiciary, Appointment and Transfer of Judges,
Qualifications, Powers and Functions.

UNIT V LOCAL ADMINISTRATION 5

District’s Administration head: Role and Importance, Municipalities: Introduction, Mayor and role of
Elected Representative, CEO, Municipal Corporation. Pachayati raj: Introduction, PRI: Zila Pachayat.
Elected officials and their roles, CEO Zila Pachayat: Position and role. Block level: Organizational
Hierarchy(Different departments), Village level:Role of Elected and Appointed officials, Importance of
grass root democracy.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT VI ELECTION COMMISSION 5

Election Commission: Role and Functioning. Chief Election Commissioner and Election Commissioners
- Institute and Bodies for the welfare of SC/ST/OBC and women.

TOTAL: 30 PERIODS
COURSE OUTCOMES:

Students will be able to:


 Discuss the growth of the demand for civil rights in India for the bulk of Indians before the arrival
of Gandhi in Indian politics.
 Discuss the intellectual origins of the framework of argument that informed the conceptualization
of social reforms leading to revolution in India.
 Discuss the circumstances surrounding the foundation of the Congress Socialist Party[CSP] under
the leadership of Jawaharlal Nehru and the eventual failure of the proposal of direct elections
through adult suffrage in the Indian Constitution.
 Discuss the passage of the Hindu Code Bill of 1956.

SUGGESTED READING
1. The Constitution of India,1950(Bare Act),Government Publication.
2. Dr.S.N.Busi, Dr.B. R.Ambedkar framing of Indian Constitution,1st Edition, 2015.
3. M.P. Jain, Indian Constitution Law, 7th Edn., Lexis Nexis,2014. 4. D.D. Basu, Introduction to
the Constitution of India, Lexis Nexis, 2015.

AC1A64 நற் றமிழ் இலக் கியம் LTPC


2000

50
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

SEMESTER - III
BM1381 HOSPITAL / BIOMEDICAL INDUSTRY TRAINING L T P C
0 0 4 2
COURSE OBJECTIVES:
 To provide hands-on experience at site where biomedical equipment’s are manufactured (industry) and
utilized (Hospitals)

SYLLABUS:
An industrial training of minimum two weeks has to be undergone by the student in the III semester. They
can choose either one of the following: Biomedical Industry, Multispecialty Hospital, Government
Medical Hospital and Private/Government R&D Medical Division. After the training, they have to submit a
report in the given prescribed format along with a copy of the certificate. During final examination,
student has to give a power point presentation about the training.
TOTAL: 60 PERIODS
COURSE OUTCOME:
At the end of the course, the student should be able to:
CO1: Get experience on various biomedical equipment’s used in hospitals
CO2: Get experience on biomedical equipment manufacturing.
CO3: Get practical knowledge of design and develop prosthetics and orthotics, drugs discovery and
Computer Aided System.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 - 3 2 1 1
2 2 - 3 2 1 1
3 3 3 2 3 3 3
Low (1); Medium (2); High (3)

BM1391 PROJECT WORK I L T P C


0 0 12 6
COURSE OBJECTIVES
 To identify a specific problem for the current need of the society and collect information related to
the same through a detailed review of literature.
 To develop the methodology to solve the identified problem.
 To identify the ethical issues for the design
 To train the students in preparing project reports and to face reviews and viva-voce examinations

SYLLABUS:
The student individually works on a specific topic of their area of interest, which is approved by faculty
member. The topic may be hardware, experimental or analytical and to analysis the ethical responsibility.
Methodology can be identified through detailed literature review based on the topic chosen to solve the
real time problem by the student. The students are trained to prepare the report and manuscript. The
students will be evaluated through a viva-voce examination by a panel of examiners including one external
examiner.
TOTAL: 180 PERIODS
COURSE OUTCOME:

On the completion of the course, the student will be able to


CO1: Apply the knowledge gained from the theoretical and practical courses, real time issues are identified.
CO2: Recognize the importance of literature review to identify the potential research gap for Developing a
methodology of their chosen topic
CO3: Finding the ethical responsibility of the chosen topic.
CO4: Report and present the findings of the work conducted.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 1 2 3 2 2
2 3 - 3 3 2 2
3 2 3 2 1 3 1
4 - 3 - - 2 -
Low (1); Medium (2); High (3)

SEMESTER IV

BM1491 PROJECT WORK II L T P C


0 0 24 12
COURSE OBJECTIVES
 To solve the identified problem based on the formulated methodology
 To carry out clinical trials/ validation with the developed product with real time data
 To publish the completed project works in a International Conference/peer reviewed Journal
with an impact factor.
SYLLABUS:

The student should continue the phase I work on the selected topic as per the formulated
methodology/ Undergo internship. The students should analyses the results of clinical trial/ validation
output taken from mentioned real time problem. At the end of the semester, after completing the
work to the satisfaction of the supervisor and review committee, a detailed report should be
prepared and submitted to the head of the department. The students will be allowed to submit
his/her project work in the form of paper for presentation/ publication in a conference/ journal and
produce the proof of acknowledgement of receipt of paper from the organizers/ publisher. The
students will be evaluated based on the report and the viva-voce examination by the panel of
examiners including one external examiner.

COURSE OUTCOME:

On the completion of the course, the student will be able to


CO1: Apply the knowledge gained from the theoretical and practical courses, to solve the identified
problems on the formulated methodology.
CO2: Carry the clinical trials / validation with real time data for the developed products, analyses and
interpret data and result.
CO3: Demonstrate an understanding of the ethics in technical writing and publish in peer reviewed
journals with conclusion of the work carried out
TOTAL: 360 PERIODS

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 1 3 3 1 2
2 3 3 3 3 3 2
3 2 3 - 1 - 1
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1331 HOSPITAL PLANNING, ORGANIZATION AND MANAGEMENT L T P C


3 0 0 3
COURSE OBJECTIVES:
 With an objective of imbibing a professional approach amongst students towards hospital
management.
 The subject encompasses management principles, staffing and marketing processes,
discussing their significance and role in the effective and efficient management of health
care organizations.

UNIT I FORMS OF ORGANISATION 8

Sole proprietorship, Partnership, Company-public and private sector enterprises, Principles of


management, Evolution of management.

UNIT II PRINCIPLE OF HOSPITAL MANAGEMENT 10

Importance of management and Hospital, Hospital Infrastructure Constraint, Management


control systems. Forecasting techniques decision-making process.

UNIT III STAFFING 6

Staffing pattern in hospitals, Selection, Recruiting process, Training of staff, Organizational


structures, Career development.

UNIT IV MARKETING AND MANAGEMENT 10

Basic concepts marketing, Principles of social marketing, Social marketing in the health sector,
Consumer behavior and research health, Advertising in Health Sector, Relevance of e-marketing
of Health care services.

UNIT V COMPUTER IN HOSPITAL 11

System Development life cycle, Reasons to use computers in hospital, main categories of
information systems in hospitals.
TOTAL: 45 PERIODS
REFERENCES
1. Goyal R.C., Human Resource Management in Hospital, Prentice Hall of India Pvt. Ltd., New
Delhi, 2000.
2. Koontz, Essentials of Management, McGraw Hill, 11th edition 2020.
3. G. D. Kunders Hospitals: Facilities Planning and Management, Tata McGrawHill Education,
New Delhi, 2004
4. Syed Amin Tabish, Hospitals & Nursing Homes: Planning, Organisations& Management,
Jaypee Brothers Medical Publishers (P) Limited, 2003

COURSE OUTCOMES:
CO1: Understand the Roles and types of establishment.
CO2: Discuss the functions of hospital management.
CO3: Understand the concepts of HR Management practices.
CO4: Discuss the methods and tools of marketing.
CO5: Understand the impacts of Information technology in hospital management

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 - 1 - 1 -
2 1 - 1 - 2 -
3 - 1 1 - 1 -
4 - - 1 - 1 -
5 1 - 1 1 2 1
Low (1); Medium (2); High (3)

BM1332 HUMAN RESOURCE MANAGEMENT IN HOSPITALS L T PC


3 00 3
COURSE OBJECTIVES:

 This subject acquaints the students with major functions of HRM aligned with the business
strategy.
 The subject encompasses the concept of best fit employee, training & executive
development, sustaining employee interest and performance appraisal

UNIT I PERSPECTIVES OF HUMAN RESOURCE MANAGEMENT 9

Evolution of Human Resource Management - Importance of Human factor, Objectives of Human


Resource Management - Human Resource Policies - Need for HRD/HRM in Healthcare
Organization- Computer Applications in Human Resource Management.

UNIT II THE CONCEPT OF BEST FIT EMPLOYEE 9

Organizational Job Design - job description - job analysis - job rotation-job evaluation- Man-
power planning- Importance of Human Resource Planning, Forecasting of Human Resource
Requirements in Health Care - Selection procedures - test, Validation, Interviews, Recruitment,
Medical Examination.

UNIT III TRAINING & EXECUTIVE DEVELOPMENT 9

Types of Training methods and their benefits - Executive development Programme - common
practices - Benefits, self-development - knowledge Management.

UNIT IV SUSTAINING EMPLOYEE INTEREST 9

Wage and Salary Administration – the concept of incentives and its operational implications –
Participative decision making – Concept of Collective Bargaining – Compensation plans – Rewards
– Motivation – Theories of motivation - Grievances and redressal methods.

UNIT V PERFORMANCE APPRAISAL 9

Importance of Performance Appraisal - Methods of Performance Evaluation, - Traditional


methods – Modern methods – Feedback – Promotion – Demotion – transfer. Implications of jobs
change. The control process, Methods and Requirements of an Effective control system.
TOTAL: 45 PERIODS

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

REFERENCES

1. R.C.Goyal, Human Resource Management in Hospitals, Prentice Hall of India, 2000.


2. Mamoria C.B. and Mamoria S. Personnel Management, Himalaya Publishing Company,
7th edition 2022.
3. Decenzo and Robbins, Human Resource Management, Wiley & Sons, Singapore,11th edition
2013.
4. D. K. Sharma, R. C. Goyal, Hospital administration and human resource management, PHI
Learning Pvt. Ltd., 2013.
5. Walter J. Flynn (Author), Robert L. Mathis (Author), John H. Jackson, Healthcare Human
Resource Management, 2006.

COURSE OUTCOMES:

On completion of this course the student will be able to:


CO1: Discuss the scope and significance of HRM.
CO2: Understand the concepts of recruitment and selection process.
CO3: Understand the procedure of training and carrier development.
CO4: Understand the employee conflicts and administrative system.
CO5: Discuss the methods and techniques of the appraisal system.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 - - 1 - 1 -
2 1 1 1 - 2 -
3 - - 1 - 1 1
4 - - - - 1 1
5 - 1 1 1 2 1
Low (1); Medium (2); High (3)

BM1333 HOSPITAL WASTE MANAGEMENT L TPC


30 03
COURSE OBJECTIVES:
 To understand the significance of infections, biomedical waste and its proper disposal.
 To teach the students about the controls applied to waste management.

UNIT I INTRODUCTION 9

Medical waste stream, different types of medical waste, its source of origin. Waste management
elements – categories of bio-medical waste, different colour codes and symbols –rules and
regulation includes state and national level bodies.

UNIT II PRINCIPLES OF STERILIZATION 9

Disease and its mode of transmission - Disinfection methods- concept and mechanism – role of
CSSD in hospital, physical sterilization and chemical sterilization – Large scale autoclave -
Microwave (Non-burn treatment technology).

UNIT III DISPOSAL OF WASTE 9

Disposal methods – Incinerator and its types-hazardous waste, radioactive waste, liquid waste
destruction – landfill and rules governing landfill.
5
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT IV CONTROLS APPLIED TO WASTE MANAGEMENT 9

Air pollution and emission control, rules governing pollution, instrumentation and monitoring,
emission filters and its types, crematories- gas emission control device. Case studies related to
air pollution.

UNIT V ENVIRONMENTAL SAFETY, RISKS & PUBLIC ISSUES 9

Risk management in hospitals - Environment issues in hospitals - Risk analysis.


TOTAL: 45 PERIODS
REFERENCES
1. C.R. BRUNNER, Medical Waste
2. C.R. BRUNNER Incentrated Consultant in Corporated Incentration System Hand Book,
Virginia.

COURSE OUTCOMES:
On completion of this course the student will be able to:
CO1: Get a clear understanding of regulations framed for waste management
CO2: Understand the significance of infections and the transmission of diseases
CO3: Acquire knowledge on proper disposal of waste
CO4: Acquire a conceptual idea about the controls applied to waste management.
CO5: Gain sufficient knowledge on Risk analysis and management of public issues.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 1 2 - - 1
2 1 1 2 1 1 1
3 - 1 1 - 1 1
4 1 1 1 1 1 1
5 1 1 1 1 2 2
Low (1); Medium (2); High (3)

BM1334 QUALITY ASSURANCE AND PATIENTS SAFETY STANDARDS IN HOSPITALS LTPC


3003
COURSE OBJECTIVES:
 To provide basic knowledge on the concept of Healthcare Quality management
towards continuous improvement of patient care.
 To make the students aware of the role of the biomedical engineer in hospitals,
especially in the management of electrical supply, maintenance of electrical safety.

UNIT I STANDARDIZATION OF QUALITY MEDICAL CARE IN HOSPITALS 9

Define Quality- Need for Standardization & Quality Management, TQM in Health care
organization-Quality assurance methods, QA in (Medical Imaging & Nuclear medicine) Diagnostic
services – Classification of equipment

UNIT II REGULATORY REQUIREMENT FOR HEALTH CARE 9

FDA regulations, Accreditation for hospitals - JCI, NABH and NABL, IEC 60601 and AERB
regulatory, other regulatory Codes.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT III HOSPITAL SAFETY 9


Security & Safety of Hospital -Property, Staff & Patients, Radiation safety, Safety precautions,
hazardous effects of radiation, allowed levels of radiation, ICRP regulations for radiation safety,
Disposal of Biological waste.

UNIT IV ELECTRICAL & FIRE SAFETY 9

Sources of shocks, macro & micro shocks -Hazards, monitoring and interrupting the Operation
from leakage current- Elements of fire, causes of fire, Action to be taken in case of fire in a
Hospital.

UNIT V ASSESSING QUALITY HEALTH CARE 9

PatientSafety Organization- Governmental & Independent, Measuring Quality care – Evaluation


of hospital services – six sigma way, Quality Assurance in Hospitals Sop‘s – Patient Orientation for
Total Patient Satisfaction. 5S technique.

TOTAL: 45 PERIODS
REFERENCES
1. B.M.Sakharkar, Principles of Hospital Administration and Planning, JAYPEE Brothers,
Medical Publishers (P) Ltd 2009.
2. Cesar A. Cacere& Albert Zana, The Practice of Clinical Engg. Academic Press, New York,
2012.
3. Joseph F Dyro “Clinical Engineering Handbook “ Elsevier Publishers,2004.
4. K.Shridhara Bhat, Quality Management, Himalaya Publishing House.
5. Karen Parsley, Karen Parsley Philomena Corrigan”Quality improvement in Healthcare,
edition, Nelson Thrones Pub,2002
6. Sharon Myers “Patient Safety & Hospital Accreditation - A Model for Ensuring Success”
Springer Publishers 2012

COURSE OUTCOMES:
On completion of this course the student will be able to:
CO1: Understand the scope of Need and significance of quality practices in health
care industry
CO2: Discuss the system of regulatory measures and accreditation
CO3: Differentiate the level of safety and security measures and significance
CO4: Understand the concepts of Electrical and Fire Safety Hazards Mitigations
CO5: Understand the assessing quality practices using tools.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 - 1 - 1 1
2 1 2 1 - 2 1
3 1 - 1 - - -
4 - - 1 - - -
5 1 1 1 1 1 1
Low (1); Medium (2); High (3)

7
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1335 TISSUE ENGINEERING LT P C


30 0 3
COURSE OBJECTIVES:
 To understand basics of tissue engineering
 To learn basics of cell mechanics in tissue engineering
 To know the importance of biomaterials in tissue engineering:
 To understand the importance of stem cell in tissue engineering
 To learn the tissue culture applications in human healthcare

UNIT I INTRODUCTION TO TISSUE ENGINEERING 9

History and scope of tissue engineering – Scientific and Social Challenges - Structure and
organization of Tissues – Development of Tissue – Cell and Extracellular matrix interaction –
Morphogenesis and Tissue Engineering – Cell Determination and Differentiation.

UNIT II FUNDAMENTALS OF CELL MECHANISMS 9

Cell adhesion, Cell migration and Cell aggregation – Cell growth and Cell cycle. Cellular
Interactions: Cell – Cell and Cell – Matrix. Control of Cell migration in Tissue Engineering –Cell
delivery and Recirculation – Cell Culture in vitro – 3D culture in Tissue Engineering - In vitro
Organogenesis - Cell transplantation.

UNIT III BIOMATERIALS IN TISSUE ENGINEERING 9

Biological vs Nonbiological materials – Extra Cellular Matrix – Collagen, Chitin & Degradable and
Nondegradable materials – Polymer, Ceramics and Metals – Cell interaction with different
materials –- Scaffolds - Control releaser agents in Tissue Engineering – Cell interaction with
suspension and gels – Tissue response to implants.

UNIT IV STEM CELLS IN TISSUE ENGINEERING 9

Introduction of Stem cells – Hemopoetic Stem cells - Embryonic Stem cells - Adult stem cells –
Cancer Stem cells – Cord Blood cells – Induced Pluripotent Stem cells - Stem cell identification -
Surface markers & FACS analysis – Differentiation, Dedifferentiation and Immortalization –
Application of stem cells in tissue Engineering.

UNIT V TISSUE ENGINEERING APPLICATIONS 9

Synthetic components – Artificial organs – Joints and dental prostheses - Connective Tissue
Engineering – Cardiovascular Tissue Engineering – Neural Tissue Engineering - Cell and Drug
Delivery systems.
TOTAL : 45 PERIODS

REFERENCES

1. R.Lanza, J.Gearhart et.al,(Eds), Essential of Stem cell Biology, Elsevier Academic Press, 2nd
edition 2009.
2. Robert P. Lanza, Robert Langer and Joseph Vacanti., Principles of Tissue Engineering, 2nd
Edition, Academic press, Elsevier 2013.
3. Gary E Wnek, Gary L Browlin – Encyclopedia of Biomaterials and Biomedical Engineering
– Marcel Dekker Inc New York, 2nd edition, 2008.

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

4. SujataV.Bhatt, Biomaterials (2nd Edition), Narosa Publishing House, 2005.


5. W. Mark Saltzman Tissue Engineering – Engineering Principles for Design of Replacement
Organs and Tissue, Oxford University Press Inc. New York, 2004.

COURSE OUTCOMES:

CO1: Explain the mechanisms involved in interaction of different materials with cells and tissues
CO2: Explain different methods involved in characterization and preparation of biomaterials in
tissue engineering
CO3: Apply the knowledge in creating new models in drug delivery systems using synthetic and
natural scaffolds
CO4: Explain different types of stem cells and its application in tissue engineering
CO5: Develop new approaches to build new tissues using tissue engineering techniques

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 3 1 2 1 2
2 2 2 1 1 1 2
3 2 2 2 1 2 1
4 2 2 2 1 2 1
5 2 2 2 3 2 2
Low (1); Medium (2); High (3)

BM1336 TROUBLESHOOTING IN MEDICAL INSTRUMENTS LTPC


3003

COURSE OBJECTIVES
 To provide adequate technical information on operating principles of medical instruments
to attain mastery in fault detection and corrective measures.
 To learn fundamental trouble shooting procedures.
 To learn how to test passive & semiconductor.
 To be able to drapnoze faults in analog and digital I C S devices
 To be able to trouble shoot Biomedical equipments.

UNIT I FUNDAMENTAL TROUBLESHOOTING PROCEDURES 9

Making of an Electronic Equipment - causes of Equipment Failure – Troubleshooting, Process &


Fault finding Aids - Troubleshooting Techniques - Grounding Systems in Electronic Equipment -
Temperature Sensitive Intermittent Problems, and Correction Action to repair the Equipment,
Tools & Aids for Servicing & Maintenance.

UNIT II TESTING OF PASSIVE COMPONENTS & SEMICONDUCTOR DEVICES 10

Different types of resistors - Capacitors, Inductors and their testing procedures - Types of
Semiconductor & its causes of failure - testing procedure for semiconductor devices - special
diodes, Bipolar Transistors, Field effect transistor (FET), Thyristors, IGBT

9
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT III FAULT DIAGNOSIS IN ANALOG & DIGITAL INTEGRATED CIRCUITS 8

Characteristics of Op-Amps - Typical Op-Amp Medical Circuits - Fault Diagnosis in Op-Amp


Circuits, Digital Troubleshooting Methods - Digital IC Troubleshooters - Circuit board
Troubleshooting - Transducers Troubleshooting.

UNIT IV BIOMEDICAL EQUIPMENT TROUBLESHOOTING –I 8

Trouble shooting - ECG Machine, EEG Machine, Defibrillator Electrosurgical Unit, Anaesthesia
Machine, Autoclaves & sterilizers, Endoscopes.

UNIT V BIOMEDICAL EQUIPMENT TROUBLESHOOTING –II 10

Troubleshooting - Incubators, Nebulizer, Oxygen concentrators, Oxygen cylinders & flowmeters,


Pulse oximeter, Sphygmomanometers, Suction Machine, X-Ray machine & Ultrasound machine,
Preventive maintenance of medical equipments.

CASE STUDIES
1. Develop an in-house computerized maintenance management system for hospitals.
2. Human Resources for medical Devices.
TOTAL: 45 PERIODS
REFERENCES
1. R S Khandpur, ‘Troubleshooting Electronic Equipment- Includes Repair & Maintenance’,
Tata McGraw-Hill, Second Edition 2009
2. Dan Tomal& Neal Widmer, ‘Electronic Troubleshooting’, McGraw Hill, 3rd Edition 2004
3. Nicholas Cram & Selby Holder, ‘Basic Electronic Troubleshooting for Biomedical
Technicians’, TSTC Publishing, 2nd Edition 2010
4. Ian R McClelland , ‘X-ray Equipment maintenance & repairs workbook for Radiographers
& Radiological Technologists’, World Health Organization,Geneva, 2004
5. Ministry of Health & Family Welfare, ‘Medical Equipment Maintenance Manual- A first
line maintenance guide for end users’, New Delhi, October2010

COURSE OUTCOMES:
CO1: To be able to calibrate and assist in equipment maintenance.
CO2: To be able to provide on and off- site assistance with the functioning of the medical
equipments.
CO3: To be able to perform as a member of multidisciplinary team in a hospital setting
CO4: Solve basic circuit problems involving DC and AC circuits
CO5: Describe the theory of operation, functioning and clinical application of medical devices

CO POs

PO1 PO2 PO3 PO4 PO5 PO6


1 2 3 1 2 1 2
2 2 2 1 1 1 2
3 2 2 2 1 2 1
4 2 2 2 1 2 1
5 2 2 2 3 2 2
Low (1); Medium (2); High (3)

10
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1341 EMBEDDED SYSTEM AND INTERNET OF THINGS FOR L T P C


BIOMEDICAL APPLICATIONS 3 0 2 4
COURSE OBJECTIVES:

 To understand hardware and software for ARM processor.


 To understand ARM processor and Building Blocks of Embedded Systems
 To provide information about sensor interfacing with Arduino
 To provide information about various protocols for IoT
 To familiarize the student with the various applications in healthcare using IOT

UNIT I ARM PROCESSOR HARDWARE AND SOFTWARE 9

Introductionto ARM Cortex-M Processors, Embedded Software Development, ARM architecture,


ARM Instruction Set, Memory System, Exceptions and Interrupts.

The C language: The evolution of C, An overview of C programming, C operators, identifiers,


keywords and constants; The C preprocessor: commands, definition and replacement, File
inclusion, Conditional compilation; storage classes, variable types, expressions and precedence,
statements, functions.
UNIT II EMBEDDED SYSTEM ARCHITECTURE - ARM CORE 9

ARM organization and implementation, The Thumb Instruction Set, Architectural Support for
High-Level Languages. Introduction to Arduino Due; Arduino integrated development
environment and programming.

UNIT III SENSOR INTERFACING WITH ARDUINO 9

Basics of hardware design and functions of basic passive components-sensors and actuators,
Arduino code - library file for sensor interfacing-construction of basic applications

UNIT IV IOT: AN INTRODUCTION 9

Networked Embedded System types and overview, wireless communication standards-zigbee,


Bluetooth & Wi-Fi. OSI & TCP/IP model in a nutshell. Introduction to the Internet and understand
how internet works. Introduction to Smart Objects or Things. IOT- understand what IOT is and
discuss its application in health-care systems- Patient Monitoring & diagnostics, Home healthcare
& Personal care & Fitness.

UNIT V EMBEDDED WEB-SERVER & IOT CLOUD SERVICES APPLICATION DESIGN & CASE STUDY 9
Embedded web server: Basic introduction, its importance and role in IOT. Design of a simple
embedded web server: understand the HTTP & HTML basics Overview of different IOT Cloud
Services.

Case Study1: Wireless Patient Monitor system


Case Study2: Wearable Fitness & Activity Monitor
Application Design: Design of IOT based pulse oximeter, block diagram, concepts of analog front
end, signal process and Wi-Fi integration.
TOTAL: 45 PERIODS

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

PRACTICAL EXERCISES: 30 PERIODS


LIST OF EXPERIMENTS

1. Code for Sensor interface: Temperature sensor, pressure sensor, Light sensor, IR sensor.
2. Temperature sensor Interfacing using ARM processor
3. Flashing of LEDs using ARM processor
4. ADC/DAC Interfacing using ARM processor
5. EPROM Interfacing using ARM processor.
6. Study of basic image processing algorithm using Single board computers such as Raspberry
Pi, Beagle Bone block etc

TOTAL: 30 PERIODS
TOTAL: 75 PERIODS
REFERENCES

1. Muhammad Ali Mazidi, Janice GillispieMazidi, Rolin D. McKinlay, “The 8051 microcontroller
and embedded systems using assembly and C”, 2nd Edition, Pearson, 2005.
2. Andrew Sloss, Dominic Symes, Chris Wright, ARM system developer’s guide: designing and
optimizing system software, Morgan Kaufmann, 2004.
3. S. Salivahanan, S.Arivazhagam, “Digital circuits and Design”, 4th Edition, Vikas Publishing
House, 2012.
4. R. S. Khandpur, “Printed Circuit Boards Design - Fabrication, Assembly and Testing”,
1stEdition, McGraw Hill Education, 2017.
5. Getting Started with Internet of Things- CunoPfister, 2011
6. Interconnecting Smart Objects with IP- J. P Vasseur, Adam Dunkels, 2010 24 Course

COURSE OUTCOMES:

After the completion of the course the student will be able to


CO1: Develop hardware and software for ARM processor.
CO2: Understand ARM processor and Building Blocks of Embedded Systems
CO3: Acquire Knowledge on sensor interfacing with Arduino
CO4: Analyse various protocols for IoT,
CO5: Build various applications in healthcare using IOT based approach and substantiate the
same with appropriate

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 3 2 3 3 1 3
2 2 1 1 2 - -
3 3 1 3 2 - 2
4 3 2 3 3 2 3
5 3 2 3 3 2 3
Low (1); Medium (2); High (3)

12
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1342 MEDICAL INFORMATICS LTPC


3024
COURSE OBJECTIVES:

 To learn about operating systems and their uses


 To understand basics of medical informatics
 To study about databases and their types
 To learn about processing of data
 To study about recent trends in health informatics

UNIT I OPERATING SYSTEM, SEARCH ENGINE AND MEDICAL STANDARD 9

Introduction to Operating systems, Linux commands, File transfer protocols ftp and telnet – Search
Engine – Online Medical Resources – Electronic Health Records - Network - Evolution of Medical
Standards – IEEE 11073 - HL7 – DICOM – IRMA - LOINC – HIPPA

UNIT II INTRODUCTION TO MEDICAL INFORMATICS 9

Introduction –Medical Informatics– Health Informatics - Structure of Medical Informatics –


Functional capabilities of Hospital Information System - On-line services and Off – line services -
Dialogue with the computer

UNIT III DATABASE AND HEALTH INFORMATICS 9

Data management – data life cycle – database technology – interfaces and implementation –
biological databases and their uses – Database management system models, Basics of Structured
Query Language (SQL). Genome projects, Clinical informatics, Nursing informatics, Public health
informatics

UNIT IV MEDICAL DATA STORAGE AND AUTOMATION 9

Representation of Data, Data modeling Techniques, Relational Hierarchical and network Approach,
Normalization techniques for Data handling - Plug-in Data Acquisition and Control Boards – Data
Acquisition using Serial Interface – Medical Data formats – Signal, Image and Video Formats –
Medical Databases - Automation in clinical laboratories - Intelligent Laboratory Information System
– PACS

UNIT V RECENT TRENDS IN MEDICAL INFORMATICS 9

Medical Expert Systems, Virtual reality applications in medicine, Virtual Environment – Surgical
simulation - Telemedicine – virtual Hospitals - Smart Medical Homes – Personalized e-health services
– Biometrics - GRID and Cloud Computing in Medicine – Artificial Intelligence in health informatics.
TOTAL: 45 PERIODS

PRACTICAL EXERCISES:

1. Computer and Internet basics


2. Operating systems – Linux and Windows Basics
3. PubMed search engine
4. Types of computer database
5. Types of graphs

13
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

6. Retrieval of data from biological and medical database


7. Data handling and analysis using Excel
TOTAL: 30 PERIODS
TOTAL: 75 PERIODS

REFERENCES

1. OrpitaBosu and Simminder Kaur Thukral, “Bioinformatics Databases, Tools and Algorithms”
Oxford University press, 2007
2. Yi Ping Phoebe Chen, “Bioinformatics Technologies”, Springer International Edition, New
Delhi, 2007.
3. R.D.Lele, “Computers in medicine progress in medical informatics”, Tata McGraw Hill
Publishing Ltd, 2005
4. Mohan Bansal, “Medical informatics”, Tata McGraw Hill Publishing Ltd, 2003
5. J.H. van Bemmel and M.A. Musen. Handbook of Medical Informatics. Bohn Stafleu Van
Loghum,. Springer
6. Robert E. Hoyt. Medical Informatics. Practical Guide for the Healthcare Professional.
Published by: Lulu.com

COURSE OUTCOMES:

After the completion of the course the student will be able to


CO1: Explain the function of hospital information systems
CO2: Explain basic concepts of artificial intelligence
CO3: Explain the various concepts of hospital management and information system
CO4: Explain the importance of medical record storage for easy access
CO5: Compare different medical standards
CO6: Explain the concepts of expert system

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 2 3 3 2 -
2 3 3 3 3 2 2
3 2 3 3 3 2 3
4 2 3 3 3 3 2
5 2 3 3 3 3 3
6 3 3 3 3 2 2
Low (1); Medium (2); High (3)

BM1343 PATTERN RECOGNITION TECHNIQUES AND APPLICATIONS L T P C


3 0 2 4
COURSE OBJECTIVES:

 To understand the fundamentals of Pattern recognition


 To impart knowledge on various clustering techniques
 To study about feature extraction and selection
 To explore different classification models
 To understand Fuzzy Pattern Classifiers and applications

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT I PATTERN CLASSIFIER 9

Overview of Pattern recognition – Discriminant functions – Supervised learning – Parametric


estimation – Maximum Likelihood Estimation – Bayesian parameter Estimation – Problems with
Bayes approach– Non Parametric techniques, Perceptron Algorithm-LMSE Algorithm- Pattern
classification by distance functions – Minimum distance pattern classifier.

UNIT II CLUSTERING 9

Clustering Concept – Hierarchical Clustering Procedures – Partitional Clustering, k- means


algorithm – Clustering of Large Data Sets – EM Algorithm – Grid Based Clustering– Density Based
Clustering.

UNIT III FEATURE EXTRACTION AND SELECTION 9

Entropy Minimization – KL Transforms – Regression-Linear, Non-linear and Logistic, Prediction,


Feature Selection through Functions Approximation – Binary Feature Selection

UNIT IV HIDDEN MARKOV MODELS AND SUPPORT VECTOR MACHINE 9

State Machines – Hidden Markov Models: Maximum Likelihood for the HMM, Forward-
Backward Algorithm, Sum and Product Algorithm for the HMM, Extensions of the Hidden
Markov Model – Support Vector Machines: Maximum Margin Classifiers, Relevance Vector
Machines

UNIT V RECENT ADVANCES AND APPLICATIONS 9

Elementary Neural Network for Pattern Recognition, Fuzzy pattern classifier, Application of PR
in image segmentation, CAD system in breast cancer detection, ECG signal classification,
Fingerprint recognition, cell cytology classification
TOTAL: 45 PERIODS
PRACTICAL EXERCISES:
1. Implementation of Perceptron Image classification using Matlab/python
2. Implementation of Fuzzy pattern classifier in Matlab/OpenCV/python.
3. Implementation of Feature extraction using KL transform in Matlab/OpenCV/python.
4. Implementation of partitional clustering in Matlab/OpenCV/python.
5. Implementation of density based clustering in Matlab/OpenCV/ python
6. Implementation of Classification using SVM in Matlab/OpenCV/python.
7. Implementation of Classification using HMM in Matlab/OpenCV/python.
8. Implementation of Bayes classifier in Matlab/OpenCV/python.
9. Implementation of Classification using Neural Networks in
10.Implementation of image segmentation in Matlab/OpenCV/python
TOTAL: 30 PERIODS
TOTAL:75 PERIODS
REFERENCES

1. Andrew Webb, “Statistical Pattern Recognition”, Arnold publishers, London,2002


2. C.M.Bishop, “Pattern Recognition and Machine Learning”, Springer, 2006
3. Earl Gose, Richard Johnsonbaugh Steve Jost, “Pattern Recognition and Image Analysis”
Prentice Hall of India Pvt Ltd., New Delhi, 2002
4. M. Narasimha Murthy and V. Susheela Devi, “Pattern Recognition”, Springer 2011
5. R.O.Duda, P.E.Hart and D.G.Stork, “Pattern Classification”, John Wiley, 2001
15
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

6. S.Theodoridis and K.Koutroumbas, “Pattern Recognition”, 4th Edition, Academic Press, 2008

COURSE OUTCOMES:
On completion of this course the student will be able to:
CO1: Perform classification using Bayes approach
CO2: Implement clustering algorithms for classification
CO3: Perform Feature extraction, feature reduction
CO4: Apply HMM and SVM for real time applications
CO5: Apply pattern recognition techniques for biosignal and medical image applications

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 - - 2 2 -
2 1 - - 2 2 -
3 2 - - 3 2 -
4 2 - - 3 1 2
5 2 - 2 3 3 2
Low (1); Medium (2); High (3)

BM1344 DATA ANALYTICS FOR HEALTHCARE TECHNOLOGIES L T PC


3 0 24
COURSE OBJECTIVES:

 To explore the various forms of electronic health care information.


 To learn the techniques adopted to analyse health care data.
 To understand the natural language based analytics
 To understand the predictive models for clinical data
 To gain knowledge health care analytics and its applications

UNIT I INTRODUCTION 9
Introduction to Healthcare Data Analytics- Electronic Health Records–Components of EHR- Coding
Systems- Benefits of EHR- Barrier to Adopting EHR-Challenges- Phenotyping Algorithms.

UNIT II DATA ANALYSIS 9


Biomedical Image Analysis- Mining of Sensor Data in Healthcare- Biomedical Signal Analysis-
Genomic Data Analysis for Personalized Medicine

UNIT III ANALTICS 9

Natural Language Processing and Data Mining for Clinical Text- Mining the Biomedical -Social Media
Analytics for Healthcare.

UNIT IV ADVANCED ANALYTICS 9

Advanced Data Analytics for Healthcare– Review of Clinical Prediction Models- Temporal Data
Mining for Healthcare Data- Visual Analytics for Healthcare- Predictive Models for Integrating
Clinical and Genomic Data- Information Retrieval for Healthcare- Privacy- Preserving Data Publishing
Methods in Healthcare

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

UNIT V APPLICATIONS 9

Applications and Practical Systems for Healthcare– Data Analytics for Pervasive Health- Fraud
Detection in Healthcare- Data Analytics for Pharmaceutical Discoveries- Clinical Decision Support
Systems- Computer-Assisted Medical Image Analysis Systems- Mobile Imaging and Analytics for
Biomedical Data.
TOTAL: 45 PERIODS
PRACTICAL EXERCISES:

1. Study of open source software


2. Data storage and retrieval on software
3. Creation of electronic patient record
4. Web page creation using HTML
5. Preprocessing the given dataset
6. User interface design
7. Univariate and Multivariate regression
8. Classification techniques
TOTAL: 30 PERIODS
TOTAL: 75 PERIODS
REFERENCES

1. Chandan K. Reddy and Charu C Aggarwal, “Healthcare data analytics”, Taylor & Francis,
2015
2. Hui Yang and Eva K. Lee, “Healthcare Analytics: From Data to Knowledge to Healthcare
Improvement, Wiley, 2016.
3. Michael Berthold, David J.Hand, “Intelligent Data Analysis”, Springer, 2007.
4. David J. Lubliner , "Biomedical Informatics: An Introduction to Information Systems and
Software in Medicine and Health", CRC Press, Boca Raton, 2016

COURSE OUTCOMES:

CO1: Understand about health care analytics and benefits of Electronic health records.
CO2: Understand about Bio medical image analysis
CO3: Understand about Natural language processing and biomedical mining
CO4: Understand about information retrieval for health care.
CO5: Demonstrate about applications and practical systems for health care

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 1 2 2 1 2
2 2 1 2 2 2 1
3 2 1 2 3 1 2
4 2 1 2 2 1 1
5 - 1 - 1 3 2
Low (1); Medium (2); High (3)

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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

BM1345 VIRTUAL /AUGMENTED REALITY L T P C


3 0 2 4
COURSE OBJECTIVES:

 To study about Fundamental Concept and Components of Virtual Reality


 To study about Interactive Techniques in Virtual Reality
 To study about Visual Computation in Virtual Reality
 To study about Augmented and Mixed Reality and Its Applications
 To know about I/O Interfaces and its functions.

UNIT I INTRODUCTION TO VIRTUAL REALITY 9

Introduction, Fundamental Concept and Components of Virtual Reality. Primary Features and
Present Development on Virtual Reality. Computer graphics, Real time computer graphics, Flight
Simulation, Virtual environment requirement, benefits of virtual reality, Historical development of
VR, Scientific Landmark 3D Computer Graphics: Introduction, The Virtual world space, positioning
the virtual observer, the perspective projection, human vision, stereo perspective projection, 3D
clipping, Colour theory, Simple 3D modelling, Illumination models, Reflection models, Shading
algorithms, Radiosity, Hidden Surface Removal, Realism Stereographic image.

Suggested Activities:
 Flipped classroom on uses of MR applications.
 Videos – Experience the virtual reality effect.
 Assignment on comparison of VR with traditional multimedia applications.
Suggested Evaluation Methods:
 Tutorial – Applications of MR.
 Quizzes on the displayed video and the special effects

UNIT II INTERACTIVE TECHNIQUES IN VIRTUAL REALITY 9

Introduction, from 2D to 3D, 3D spaces curves, 3D boundary representation Geometrical


Transformations: Introduction, Frames of reference, Modeling transformations, Instances, Picking,
Flying, Scaling the VE, Collision detection Generic VR system: Introduction, Virtual environment,
Computer environment, VR technology, Model of interaction, VR Systems.

Suggested Activities:
 Flipped classroom on modeling three dimensional objects.
 External learning – Collision detection algorithms.
 Practical – Creating three dimensional models.

Suggested Evaluation Methods:


 Tutorial – Three dimensional modeling techniques.
 Brainstorming session on collision detection algorithms.
 Demonstration of three dimensional scene creation.

UNIT III VISUAL COMPUTATION IN VIRTUAL REALITY 9

Animating the Virtual Environment: Introduction, The dynamics of numbers, Linear and Nonlinear
interpolation, the animation of objects, linear and non-linear translation, shape & object

18
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

inbetweening, free from deformation, particle system. Physical Simulation: Introduction, Objects
falling in a gravitational field, Rotating wheels, Elastic collisions, projectiles, simple pendulum,
springs, Flight dynamics of an aircraft.

Suggested Activities:
 External learning – Different types of programming toolkits and Learn different types of
available VR applications.
Practical – Create VR scenes using any toolkit and develop applications.
Suggested Evaluation Methods:

 Tutorial – VR tool comparison.


 Brainstorming session on tools and technologies used in VR.
 Demonstration of the created VR applications.

UNIT IV AUGMENTED AND MIXED REALITY 9

Taxonomy, technology and features of augmented reality, difference between AR and VR,
Challenges with AR, AR systems and functionality, Augmented reality methods, visualization
techniques for augmented reality, wireless displays in educational augmented reality applications,
mobile projection interfaces, marker-less tracking for augmented reality, enhancing interactivity in
AR environments, evaluating AR systems

Suggested Activities:
 External learning - AR Systems

Suggested Evaluation Methods:


 Brainstorming session different AR systems and environments.

UNIT V I/O INTERFACE IN VR & APPLICATION OF VR 9

Human factors: Introduction, the eye, the ear, the somatic senses. VR Hardware: Introduction,
sensor hardware, Head-coupled displays, Acoustic hardware, Integrated VR systems. VR Software:
Introduction, Modeling virtual world, Physical simulation, VR toolkits, Introduction to VRML, Input -
- Tracker, Sensor, Digitalglobe, Movement Capture, Video-based Input, 3D Menus and 3DScanner
etc. Output -- Visual /Auditory / Haptic Devices. VR Technology in Film & TV Production. VR
Technology in Physical Exercises and Games. Demonstration of Digital Entertainment by VR.

Suggested Activities:

 External learning – Different types of sensing and tracking devices for creating mixed
reality environments.
 Practical – Create MR scenes using any toolkit and develop applications.
Suggested Evaluation Methods:
 Tutorial – Mobile Interface Design.
 Brainstorming session on wearable computing devices and games design.
 Demonstration and evaluation of the developed MR application.
TOTAL: 45 PERIODS
PRACTICALS:
1. Study of tools like Unity, Maya, 3DS MAX, AR toolkit, Vuforia and Blender.
2. Use the primitive objects and apply various projection methods by handling the camera.
3. Download objects from asset stores and apply various lighting and shading effects.
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

4. Model three dimensional objects using various modeling techniques and apply textures
over them. Create three dimensional realistic scenes and develop simple virtual reality
enabled mobile applications which have limited interactivity.
5. Add audio and text special effects to the developed application.
6. Develop VR enabled applications using motion trackers and sensors incorporating full
haptic interactivity.
7. Develop AR enabled applications with interactivity like E learning environment,
Virtual walkthroughs and visualization of historic places.
8. Develop MR enabled simple applications like human anatomy visualization,
DNA/RNA structure visualization and surgery simulation.
9. Develop simple MR enabled gaming applications.
TOTAL: 30 PERIODS
TOTAL: 75 PERIODS
REFERENCES
1. Burdea, G. C. and P. Coffet. Virtual Reality Technology, Second Edition. Wiley-IEEE Press,
2003/2006.
2. Alan B. Craig, Understanding Augmented Reality, Concepts and Applications, Morgan
Kaufmann,First Edition 2013.
3. Alan Craig, William Sherman and Jeffrey Will, Developing Virtual Reality Applications,
Foundations of Effective Design, Morgan Kaufmann, 2009.
4. John Vince, “Virtual Reality Systems “, Pearson Education Asia, 2007.
5. Adams, “Visualizations of Virtual Reality”, Tata McGraw Hill, 2000.
6. Grigore C. Burdea, Philippe Coiffet , “Virtual Reality Technology”, Wiley Inter Science, 2nd
Edition, 2006.
7. William R. Sherman, Alan B. Craig, “Understanding Virtual Reality: Interface, Application and
Design”, Morgan Kaufmann, 2008

COURSE OUTCOMES:
CO1: Understand the Fundamental Concept and Components of Virtual Reality
CO2: Able to know the Interactive Techniques in Virtual Reality
CO3: Can know about Visual Computation in Virtual Reality
CO4: Able to know the concepts of Augmented and Mixed Reality and Its Applications
CO5: Know about I/O Interfaces and its functions.

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 1 2 3 3 2
2 3 3 3 3 2 2
3 2 3 3 3 2 3
4 2 3 3 3 3 2
5 2 3 3 3 3 3
Low (1); Medium (2); High (3)

BM1346 PHYSIOLOGICAL MODELING AND COMPUTATION LTPC


3024
COURSE OBJECTIVES
 To understand about models and analogs in different systems.
 To gain knowledge about linear, non linear, distributed and lumped parameter models.
 To analyze the response of the system by any methods like frequency response, transient
response and steady state responses

20
PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

 To learn simulation of models using MATLAB tools


 To design a model, simulate and analyze any kind of physiological systems

UNIT I INTRODUCTION TO PHYSIOLOGICAL MODELING 9

Model- Definition, various analogs, Physiological systems-A simple example, Generalized system
properties- Resistance, Compliance, Impedance, Across variable, through Variable, Models with
combination of system elements, Linear- vs nonlinear- models of physiological systems, Action
potentials Hodgkin-Huxley model by MATLAB tools, Distributed Vs Lumped parameter models,
Compartment models

UNIT II FREQUENCY DOMAIN ANALYSIS AND TRANSIENT RESPONSE ANALYSIS 9

Frequency domain- Linearized model of lungs mechanics and their SIMULINK implementation,
model of chyne-stokes breathing, circulatory control model, cardiac output, glucose insulin
regulation model by MATLAB tools, transient response analysis of neuromuscular reflex model
action by MATLAB tools.

UNIT III MODELING BODY DYNAMICS 9

Mechanical modeling of bone and tissues, linear muscle model, Study of steady state analysis of
muscle stretch reflex action by MATLAB tools, Hills’ model of muscle contraction, Oculomotor
muscle model, modeling of human movements, Pharmacokinetic modeling with drug diffusion as
example

UNIT IV MODELING OF EYE AND HOMEOSTATIC SYSTEMS 9

Eye movement system and Wetheimer’s saccade eye model, closed loop aspects of papillary control
system, Open loop papillary response of papillary-retinal system, Homeostatic lumped model of
physiological thermal system, models of heat transfer between subsystems of human body,
Homeostatic control of adrenocortical secretion.

UNIT V NON PARAMETRIC AND PARAMETRIC MODELING 9

Non parametric models- Volterra models, Wiener models, Parametric Models – Basic parametric
model forms and estimation procedures, Volterra Kernels of non linear differential equations,
Discrete time Volterra Kernels of NARMAX models.
TOTAL: 45 PERIODS
PRACTICALS:
1. SIMULINK model of simple lung mechanics
2. Simulation of Hodgkin – Huxley model of nerve membrane
3. Steady state analysis of muscle stretch reflex model
4. SIMULINK model to determine the steady state operating point of the ventilator control system
5. Second order lung mechanics model to a unit impulse
6. SIMULINK implementation of neuromuscular reflex model
7. SIMULINK model of circulatory control
8. SIMULINK model of blood glucose-insulin regulations
9. Frequency responses of the linearized ventilator control by Nyquist plots
10. Cardiovascular variability model with feedback
TOTAL: 30 PERIODS
TOTAL: 75 PERIODS
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PSNACET (Autonomous), Dindigul -624 622 Regulations 2022 ME BME

REFERENCES
1. William B. Blesser, “A System approach to Bio-medicine”, McGraw-Hill book co., New York, 2nd
Edition, 1981
2. Michael C. K. Khoo, “Physiological control systems: Analysis, Simulation and Estimation”,
Prentice-Hall of India Pvt. Limited, first edition, 2000.
3. Manfreoclynes and john H.Milsum, “Bio-medical engineering system” McGraw-Hill book co.,
NewYork, first edition, 1970.
4. Douglas S. Regs, “Control theory and physiological feedback mechanism” The William &Williams
co., Baltimore, first edition, 1970.
5. Simpson, W. 2006. Video over IP. A practical guide to technology and applications. Focal Press
(Elsevier). ISBN-10: 0-240-80557-7.

COURSE OUTCOMES:
CO1: Explain the application of Physiological models and vital organs
CO2: Formulate the methods and techniques for analysis and synthesis of dynamic models
CO3: Describe the dynamic models, simulate and visualize, dynamic responses of physiological
models using software
CO4: Describe nonlinear models of physiological systems
CO5: Compute the Simulation of physiological systems

CO POs
PO1 PO2 PO3 PO4 PO5 PO6
1 2 1 - - - -
2 1 1 1 - - -
3 1 1 - - - -
4 2 2 2 3 3 3
5 2 2 2 1 2 3
Low (1); Medium (2); High (3)

22

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