NBME USMLE Infographic Final
NBME USMLE Infographic Final
To help ensure the relevancy of content covered on the USMLE® Step exams, an updated content outline is now available. Foundational
science content has been recategorized into organ system categories and a new category titled “Human Development*”.
Human Development*
Immune System
The USMLE’s “General Principles of Foundational Science”
content has been redistributed, not removed. As a result, Blood & Lymphoreticular System
the following topics will still be assessed within an organ Behavioral Health
system/disease process on Step 1: Nervous System & Special Senses
• Biochemistry and molecular biology Skin & Subcutaneous Tissue
• Biology of cells RECATEGORIZED Musculoskeletal System
• “Human Development*” and genetics FOUNDATIONAL
SCIENCE Cardiovascular System
• Biology of tissue response to disease CONTENT Respiratory System
• Pharmacodynamic and pharmacokinetic processes
Gastrointestinal System
• Microbial biology
• Normal structure and function of organ systems Renal & Urinary System
Pregnancy, Childbirth & the Puerperium
Normal age-related findings and care of the well patient
Female Reproductive System & Breast
topics will be categorized under “Human Development*”.
Male Reproductive System
Endocrine System
Multisystem Processes & Disorders
Biostatistics, Epidemiology/Population Health
& Interpretation of the Medical Literature
Social Sciences