LSS 2 2014
LSS 2 2014
a) Table of Na+,K+ and Ca2+ and you had to circle which ones are high and low intracellularly
and extracellularly (3)
b) Give 3 types of gated channels (3)
c) What two transporters create a membrane potential in these cells? (1)
d) Give an example on how the sodium channel gradient is used in (do not repeat the same
mechanism for any answer): (3)
i) Heart
ii) Kidney
iii) Intestine
Urinary
Some of the boxes in this EXACT image were replaced with letters.
a) When blood volume decreases, the heart produces less of A. What hormone is A? (1)
b) When volume decreases, the brain makes more B. What is B? (1)
c) C is a renal enzyme that turns Angiotensinogen into AT1. What is C? (1)
d) What happens to the levels of the enzyme in part C when blood volume decreases? (2)
e) AT1 is converted to D. What is D? (1)
e) What enzyme in the lung causes the step described above? (1)
f) When blood volume decreases, what happens to Aldosterone concentrations? (1)
g) Explain the mechanisms for changes in concentrations of A, B and aldosterone on blood
volume (2 marks)
Alimentary
a) Name three types of acute live failure. (3)
b) What is the main cause of acute liver disease in the UK? (1)
c) Name three symptoms that patients with chronic liver failure will show. (3)
d) Name three common clinical signs in patients with chronic liver failure. (3)
EMQs
1) Image of CT abdomen. It was actually a fairly tricky one. Had to point out the diaphragm
(innervated by C3-5), liver, area where tumour is most likely to cause post hepatic
jaundice, area that is attached to the superior part of the pubis and the gallbladder I
THINK
2) Second one, were given a bunch of secretions/functions/structures, and had to match it
the corresponding organ. Stomach, oesophagus, small intestine, gallbladder and liver.
3) Three was a bunch of channels and transporters. Had to match them with the function.
Included Calbindin, Ferroportin, VitB12, DMT-1, etc…