Science10 q4 Mod5 Biomoleculeslipids v5
Science10 q4 Mod5 Biomoleculeslipids v5
Science10 q4 Mod5 Biomoleculeslipids v5
Science
10
Quarter 4 - Module 5
Biomolecules: LIPIDS
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Objectives:
Pre Assessment
TRUE OR FALSE. Analyze each statement carefully. Write TRUE if the statement is
correct and write FALSE if the statement is not correct in your answer sheet.
1. Lipids are non-polar molecules.
2. Lipids can be synthesized in the muscle of our body.
3. Lipids are good conductors of heat.
4. When a part of unsaturated fatty acid oxidized to form aldehyde ketone, the
phenomenon is termed as hydrolytic rancidity.
5. Alkaline hydrolysis of fats results in the formation of glycerol and long chain of
fatty acid.
6. Lipids serve as structural components of cell membranes.
7. The carbon-carbon double bonds in unsaturated fatty acids can be hydrogenated
by reacting with hydrogen to produce saturated fatty acids.
8. Lipids are soluble in ether.
9. The consistency of lipids depends upon the presence of an emulsifier.
10. Acid hydrolysis results in the formation of sodium or potassium salts of fatty acids
called as soaps.
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Prior Knowledge
In the previous lesson, you have learned that carbohydrates are important in
providing “instant” energy for cells. There is another class of biomolecules called lipids that
have the “job” of storing energy for later use. Lipids are also found in hormones and cell
membrane components.
b. PRESENTATION
Do you know what lipids are? Do you think it is important to our existence? Can we live
without them? Did you not wonder where they came from and how do they behave as
molecules of life? These and some other questions will be answered as we go through
this lesson.
Concept Development
Lipids
These organic compounds are nonpolar molecules, which are soluble only in nonpolar
solvents and insoluble in water because water is polar molecules. In the human body, these
molecules can be synthesized in the liver and are and generally found in the oil, butter,
whole milk, cheese, fried foods, and also in some red meats.
Figure 1 shows Lipids as the waxy, greasy, or oily compounds found in plants and animals.
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Lipid Structure
Lipids are the polymers of fatty acids that contain a long, non-polar hydrocarbon chain
with a small polar region containing oxygen. The lipid structure is explained in the
diagram below:
Figure 2 shows that lipids are composed of carbon, hydrogen and oxygen atoms, and in
some cases contain phosphorus, nitrogen, sulfur and other elements.
Figure 3 shows the overview of what lipids are in terms of its type and
classification. However, major discussion on this matter will be on lessons 2 and 3 of
this module.
Properties of Lipids
Some of key properties of lipids include energy storage for animals and other organisms
while others are described below:
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1. Solubility: Lipids are soluble in non-polar solvent (ether, chloroform, benzene etc) but
insoluble in water.
2. Consistency: They are colorless, odorless and tasteless. Being lighter than water
they have a specific gravity of 0.86. The consistency of lipids depends upon the
presence of saturated and/or unsaturated fatty acids.
3. Hydrolysis: It is brought about in presence of acids or alkalis under the activity of
enzyme lipases. Acid hydrolysis results in the formation of glycerol and long chain of
fatty acid whereas alkaline hydrolysis of fats results in the formation of sodium or
potassium salts of fatty acids called as Soaps and the process is called as
saponification.
4. Hydrogenation: The carbon-carbon double bonds in unsaturated fatty acids can be
hydrogenated by reacting with hydrogen to produce saturated fatty acids. Ex. The
conversion of liquid vegetable oil into solid vegetable ghee by reacting with hydrogen
gas in the presence of catalyst (Ni) at 200º C.
5. Emulsification: When fats or oils are rubbed with water, the large molecules of lipids
broke into smaller ones forming the emulsion and the process is called emulsification.
6. Rancidity: When lipids are exposed to atmosphere (heat, light, air, moisture) for more
than 30 days, an unusual and undesirable odor is developed. Such types of lipids are
called rancid lipids and the phenomenon is termed as Rancidity. Rancidity is of two
types: (a) Hydrolytic and (b) Oxidative
a. Hydrolytic Rancidity: This type of phenomenon occurs due to liberation of volatile
acids during the hydrolysis of fats.
b. Oxidative rancidity: When a part of unsaturated fatty acid oxidized to form aldehyde
ketone, the phenomenon is termed as oxidative rancidity.
Lipids cushion organs. Our underlying muscles are protected from trauma by a fatty hypodermis.
We have fatty pads in our knees. A layer of fat surrounds our kidneys. Fat covers our hearts,
internal viscera, spinal cord and eyeballs. All this fat protects these vital organs from the bumps
and bruises of life. Hooray for fat!
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Lipids are waterproofing. Waterfowl stay dry and buoyant by coating their feathers in oil.
Waxing your car protects it from the corrosive power of water.
Activities
Answer the following in a separate sheet of paper:
1. Are lipids organic molecules? _____________ Why or why not?
_____________________________
2. What common elements do lipids contain?
1. ____________________________
2. ____________________________
3. ____________________________
3. Label the lipids below as either saturated or unsaturated.
A.
B.
Lipids are organic compounds that are _________ molecules, which are soluble
only in _______ solvents and _________ in water because water is polar
molecules.
Lipids are the polymers of __________that contain a long, non-polar hydrocarbon
chain with a small polar region containing____________.
In the human body, lipid molecules can be synthesized in the _________ and are
and generally found in the oil, butter, whole milk, cheese, fried foods, and also in
some red meats.
Lipids are colorless, odorless and tasteless. Being lighter than water, they have a
__________ of 0.86.
When a part of unsaturated fatty acid oxidized to form aldehyde ketone, the
phenomenon is termed as________________.
8
The consistency of lipids depends upon the presence of ___________ and/or
____________.
Acid hydrolysis results in the formation of ___________and long chain of fatty
acid.
Alkaline hydrolysis of fats results in the formation of _________________ of fatty
acids called as soaps and the process is called as ___________________.
Hydrolytic Rancidity is a type of phenomenon occurs due to liberation of volatile
acids during the hydrolysis of ______________.
When fats or oils are rubbed with water, the large molecules of lipids are broken
into smaller ones forming the emulsion and the process is called ___________.
c. APPLICATION
Briefly explain the following.
1. Describe lipids.
2. What are the major functions of lipids?
3. Why lipids are “waterproof”?
4. Name the three biological functions of lipids.
d. GENERALIZATION
Lipids are organic compounds that are nonpolar molecules, which are soluble
only in nonpolar solvents and insoluble in water because water is polar
molecules. In the human body, these molecules can be synthesized in the
liver and are and generally found in the oil, butter, whole milk, cheese, fried
foods, and also in some red meats.
The primary function lipids is to store energy for future use. They include a
diverse group of largely nonpolar, insoluble, hydrocarbon molecules.
Lipids are biological molecules that are insoluble in water but soluble in
nonpolar solvents.
Lipids have a wider spectrum of compositions and structures because they
are defined in terms of their physical properties (water solubility).
Moreover, lipids perform three primary biological functions within the body:
they serve as structural components of cell membranes, function as energy
storehouses, and function as important signaling molecules.
e. POST ASSESSMENT
MULTIPLE CHOICE: Choose the letter of the best answer. Write the chosen
letter on a separate sheet of paper.
9
1. What is the solubility of lipids in water?
A. Insoluble B. Partially insoluble C. Partially soluble D. Soluble
2. Which of the following reagent is/are used in Saponification?
A. Ammonia B. Acetic acid
C. Butanone D. sodium hydroxide/potassium hydroxide
3. Which of the following is not true about lipids?
A. They are insoluble in water
B. They are more soluble in water
C. They are either strongly hydrophobic or amphipathic
D. Extraction of lipids from tissues require organic solvents
4. Which of the following statement istrue?
A. Plant fats do not undergo oxidative rancidity
B. Oxidative rancidity can be effectively checked by dehydration of fatty acids
C. Oxidative rancidity is observed more frequently in animal fats than in
vegetable fats
D. Oxidative rancidity is observed more frequently in vegetable fats than in
animal fats.
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Lesson
Lipids: Fatty Acids &
2 Glycerides
a. OVERVIEW
Now that you have background ideas on what lipids are, we are going to explore
more on their classification. We will learn about the first two classifications of lipids- the
fatty acids and glycerides. We will investigate on their classes, structures, sources, uses
and functions.
Objectives
Pre-Assessment
Multiple Choice: Select the correct answer from the given choices. Write your answer
in a separate sheet of paper.
11
Prior Knowledge
b. PRESENTATION
Lipids are also the building blocks of many hormones and are an important
constituent of all cellular membranes. They include fats, oils, waxes, phospholipids, and
steroids.
Do you know how these molecules function? Do you think it is important to our
existence? Where can you find these molecules? Is it important in the living systems?
These and some other questions will be tackled in this lesson.
Now, we will look into the classification of lipids. We will familiarize some of them
since we have encountered them and used them in our day-to-day activities.
Concept Development
Classification of Lipids
Lipids are commonly subdivided into four main groups . The diagram below
shows the major classification of lipids. We will discuss thoroughly the first two
classifications in this lesson and the next two on the next lesson.
Study the diagram below and familiarize yourself on the 4 major classification of lipids.
12
Source: https://alevelbiology.co.uk/notes/lipids-introduction-and-classification/
They are usually have straight chains (no branches) that are about 10 to 20 carbon
atoms in length.
• They usually have an even number of carbon atoms (counting the carboxyl carbon).
• The carbon chains may be saturated (all single bonds) or unsaturated (containing
double bonds). Other than the carboxyl group and the double bonds, there are usually
no other functional groups.
• Shorter fatty acids usually have lower melting points than longer ones (stearic acid
[18C] = 70ºC, palmitic acid [16C] = 63ºC).
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Figure 2. Stearic acid, a saturated fatty acid
Source: https://library.med.utah.edu/NetBiochem/FattyAcids/3_3.html
Note that as the number of carbon atoms increases, the melting point of the fatty acids
increases.
Numbering of unsaturated fatty acids starts from the other end of -COOH
See structural notation: it indicates number of C atoms E.g., 18:2 – 18 carbons, 2
double bonds.
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Figure 3. Structural formula of Oleic acid, a monounsaturated fatty acid
Source: . https://library.med.utah.edu/NetBiochem/FattyAcids/3_3.html
2. Polyunsaturated fatty acids- when the fatty acids have more than one double
bond- up to six double bonds are present in fatty acids. (Ex. Canola oil).
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Table 2. Some Samples of Unsaturated Fatty acids
No. Name Chemical Formula Melting Common Sources
Point (
° C)
Monounsaturated
16 Palmitoleic acid -1ºC Cod liver oil,
CH3(CH2)5CH=CH(CH2)7COOH butterfat
18 Oleic acid 13 Lard, beef fat, olive
CH3(CH2)7CH=CH(CH2)7COOH oil, peanut oil
Polyunsaturated
18 Linoleic acid -5 Cottonseed oil,
CH3(CH2)4(CH=CHCH2)2(CH2)6COOH soybean oil, corn
oil, linseed oil
18 Linolenic acid -11 Linseed oil, corn oil
CH3CH2(CH=CHCH2)3(CH2)6COOH
20 Arachidonic acid -50 Corn oil, linseed oil,
CH3(CH2)4(CH=CHCH2)4(CH2)2COOH animal tissues
20 Eicosapentaenoic acid CH3CH2(CH=CHCH2)5(CH2)2COOH Fish oil, seafoods
22 Docosahexaenoic acid CH3CH2(CH=CHCH2)6CH2COOH Fish oil, seafoods
Source:
www.chem.latech.edu › ~upali › chem121 › Notes-C19-121
www.angelo.edu › kboudrea › index_2353 › Chapter_08_2SPP
Unsaturated fats are considered healthier due to their calorie content. The carbon-
hydrogen covalent bond is packed with energy. The more of these bonds in a molecule, the
more calories in the molecule has. Since saturated fats have a maximum number of carbon-
hydrogen bonds, they have the most calories. In our calorie conscious times, saturated fats are
super energy rich. So when choosing a lower calorie fat, unsaturated is a healthier choice.
Essential Fatty Acids: Must be part of diet. They are fatty acids that cannot be produced by
the body and are necessary for proper metabolism. The OMEGA 6 and OMEGA 3 fatty acids
are referred to as Essential Fatty Acids (EFA).
1. Omega-6 Series
Linoleic Acid (LA) -- LA is the essential fatty acid from which Gamma Linolenic Acid
(GLA) is derived.
Gamma linolenic Acid (GLA) -- GLA is found primarily in mother's milk and Evening
Primrose seeds. Moderate but variable amounts are found in borage and
blackcurrant seeds.
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Dihomogamma linolenic Acid (DGLA) -- DGLA is found in mother's milk and organ
meats such as spleens, kidneys and adrenals.
Arachidonic Acid (AA) -- AA is found in meats, dairy products and seafood such as
shrimps and prawns.
2. Omega-3 Series
Alpha linolenic Acid (ALA) -- ALA is found in green, leafy vegetables and linseed
(GLA) oils.
Eicosapentaenoic (EPA) -- EPA is found primarily in marine and fish oils.
Docosahexaenoic (DHA) -- DHA found primarily in marine and fish oils.
Trans Fats
In the food industry, oils are artificially hydrogenated to make them semi-solid and of a
consistency desirable for many processed food products. Simply speaking, hydrogen gas is
bubbled through oils to solidify them. During this hydrogenation process, double bonds of the
cis– conformation in the hydrocarbon chain may be converted to double bonds in the trans–
conformation.
Margarine, some types of peanut butter, and shortening are examples of artificially
hydrogenated trans fats. Recent studies have shown that an increase in trans fats in the human
diet may lead to an increase in levels of low-density lipoproteins (LDL), or “bad” cholesterol,
which in turn may lead to plaque deposition in the arteries, resulting in heart disease. Many fast
food restaurants have recently banned the use of trans fats, and food labels are required to
display the trans-fat content.
II. GLYCERIDES
Glycerides, or fatty acid esters of glycerol, are the major components of natural fats and oils.
They may be subdivided into two classes: neutral glycerides and phosphoglycerides:
The structures of each of these types of glycerides are critical to their function. The
esterification of glycerol with a fatty acid produces a neutral glyceride. Esterification may
occur at one, two, or all three positions, producing monoglycerides, diglycerides, or
triglycerides. Although monoglycerides and diglycerides are present in nature, the most
important neutral glycerides are the triglycerides, the major component of fat cells.
Triglycerides
Animal fats and vegetable oils are triglycerides (or triacylglycerides), in which three fatty acid
residues are joined to glycerol by ester bonds. Triglycerides are produced during dehydration
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synthesis when the hydroxyl groups on the glycerol backbone react with the carboxyl groups of
fatty acids.
During this reaction, water molecules are lost, resulting in a triglyceride with three fatty acid tails
bound to the glycerol backbone via ester linkages.
One of the key parts that make up a lipid is glycerol (a type of alcohol). An alcohol is
recognizable by its hydroxyl (-OH) groups.
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usually derived from animals and mostly saturated fatty acids
usually derived from plants or fish and mostly unsaturated fatty acids
The primary biological roles of triglycerides in animals are: energy storage, the
production of energy when metabolized and the provision of fatty acids for the
production of other lipids insulation.
Phospholipids are the major components in the lipid bilayers of cell membranes. There are two
common phospholipids:
Lecithin contains the amino alcohol, choline. Lecithin is probably the most common
phospholipid. It is found in egg yolks, wheat germ, and soybeans. Lecithin is extracted
from soybeans for use as an emulsifying agent in foods.
Cephalins contain the amino alcohols serine or ethanolamine. Cephalins are found in
most cell membranes, particularly in brain tissues. They are also important in the blood
clotting process as they are found in blood platelets
Activities
1.
2.
3.
4.
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5.
Assessment
Multiple Choice: Select the correct answer from the given choices. Write your answer in a
separate sheet of paper.
8. The melting point of fatty acids depends upon chain length and _________
A. Charge on the carbon B. Degree of unsaturation
C. The shape of the fatty acids D. The position of the double bond
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c. APPLICATION
Draw the structural formula of the following substance.
d. GENERALIZATION
Fatty acids are long-chain monocarboxylic acids. As a consequence of their biosynthesis,
fatty acids generally contain an even number of carbon atoms.
The general formula for a saturated fatty acid is CH 3(CH2)n COOH, in which n in biological
systems is an even integer.
Fatty Acids are divided into two: Saturated and Unsaturated.
Saturated fatty acids have even number of Carbon atoms. It consists of carbon-carbon
single bonds.
As the number of carbon atoms increases, the melting point of the fatty acids increases.
Unsaturated Fatty Acids consist of either one or more double bonds.
Monounsaturated: When there is only one double bond in each fatty acid as in olive oil.
Polyunsaturated fatty acids- when the fatty acids have more than one double bond- up to
six double bonds are present in fatty acids as in Canola oil.
Unsaturated fats are considered healthier due to their calorie content. The carbon-
hydrogen covalent bond is packed with energy.
Essential Fatty Acids are fatty acids that cannot be produced by the body and are
necessary for proper metabolism. They must be part of the diet. Examples are OMEGA 6
and OMEGA 3.
Glycerides (glycerol-containing lipids) - are lipid esters that contain the glycerol molecule
and fatty acids.
Animal fats and vegetable oils are triglycerides (or triacylglycerides), in which three fatty
acid residues are joined to glycerol by ester bonds.
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Saturated triglyceride molecules do not contain carbon-carbon double bonds.
Phospholipids are the major components in the lipid bilayers of cell membranes.
e. POST ASSESSMENT
Multiple Choice: Select the correct answer from the given choices. Write your answer in a
separate sheet of paper.
1. Which of the following molecules is a typical fatty acid?
A. A polar hydrocarbon with that reacts with NaOH to form a salt
B. A molecule that has one cis double bond in a linear carbon chain.
C. An amphipathic dicarboxylic acid with unconjugated double bonds.
D. A molecule that has an even number of carbon atoms in a branched chain.
2. What are the components of a triglyceride molecule?
A. One glycerol and one cholesterol B. One glycerol and two fatty acids
C. One cholesterol and two fatty acids D. One glycerol and three fatty acids
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6. The main difference between saturated and unsaturated fatty acids is
A. the presence of carbons. C. the presence of keto groups.
C. the presence of double bonds. D. he presence of triple bonds.
Lesson
Classes of Lipids: Lipoprotein
3 and Nonglycerides
a. OVERVIEW
Now that you have already learned on the properties, structures, uses and sources of
the first two classes of lipids, you are now going to explore on the other two classes of
lipids- lipoprotein and nonglycerides.
Objectives
At the end of the lesson, you are expected to:
1. Describe the classes, structure, sources, uses and functions of lipoprotein
2. Describe the classes, structure, sources, uses and functions of nonglycerides
Pre-Assessment
Multiple Choice: Select the correct answer from the given choices. Write your answer
in a separate sheet of paper.
1. Which of the following phospholipid is considered as a major constituent of nervous tissue?
A. Glycerophospholipid B. Inositol C. Plasmalogen D. Sphingomyelin
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6. Which characteristic does this lipid share with a wax?
A. Both contain a polar head.
B. Both contain three fatty acids.
C. Both contain one or more ester bonds.
D. Both contain one or more carboxyl groups.
Prior Knowledge
Our previous lesson talks about the first two classes of lipids- the Fatty acids and
glycerides. You learn about their chemical structures, their properties and derivatives,
and their examples. You also learn how they function as important molecules of life.
Knowing the two classes of lipids, you can now classify them since you need it and
used it to sustain life.
b. PRESENTATION
If you still remember, you get to know the first two classes of lipids in the previous
lesson. In this lesson, we will get to know the last two classes which are the
nonglycerides and the complex lipids or lipoprotein.
Did you not wonder why they are considered biomolecules or molecules of life?
Did you hear that your parents or siblings undergone lipid profile as ordered by their
doctor? Why do you think the doctor did so? Why many people do experience having
high blood pressure, high cholesterol, suffered from heart diseases? How does it relate
to our study on lipids?
These and some other questions will be answered as we go through on this lesson.
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Concept Development
NONGLYCERIDE LIPIDS (sphingolipids, steroids, waxes)
Nonglyceride lipids is further subdivided into three: Sphingolipids, steroids and waxes.
I. SPHINGOLIPIDS are lipids that are not derived from glycerol. Sphingolipids
are found in essentially all plants, animals, fungi and in some prokaryotes and
viruses. Specifically, they are found in membranes and as a major component
of lipoproteins.
Sphingolipids are of two types: sphingomyelins and Glycolipids
25
Cholesterol is an essential component of cell membranes, and is a precursor for other
steroids, such as the bile salts, sex hormones, vitamin D, and the adrenocorticoid
hormones.
2. Steroid Hormones
Hormones, molecules that regulate the function of organs and tissues, come in a variety
of forms.
• Some, such as sex hormones and adrenocorticoid hormones, are steroids.
Steroid hormones are made from cholesterol and are secreted by three
“steroid glands”—the adrenal cortex, testes, and ovaries—and during pregnancy by
the placenta.
3. Bile salts are made of bile acids that are conjugated with glycine or taurine.
They are produced in the liver, directly from cholesterol
Glycocholate, taurocholate, and other bile salts are released from the
gallbladder into the small intestine, where they aid digestion by forming
emulsions with dietary lipids.
Gallstones
Bile salts also emulsify cholesterol in the bile, so it can be removed in the small
intestine. If cholesterol levels are too high or the levels of bile salts is too low,
the cholesterol precipitates and forms gallstones.
26
Many plants have leaves and fruits with wax coatings to help prevent
water loss. Some animals also have wax-coated fur or feathers to repel water.
Unlike most waxes, ear wax is composed of phospholipids and esters of
cholesterol.
Waxes are derived from many different sources and have a variety of chemical
compositions, depending on the source.
Paraffin wax, for example, is composed of a mixture of solid
hydrocarbons (usually straight-chain compounds).
Beeswax is an ester formed by combining palmitic acid with a 30-carbon
alcohol.
The natural waxes generally are composed of a long-chain fatty acid
esterified to a long-chain alcohol.
Because the long hydrocarbon tails are extremely hydrophobic, waxes
are completely insoluble in water.
Waxes are also solid at room temperature, owing to their high molecular
weights.
Two examples of waxes are myricyl palmitate, a major component of
beeswax, and whale oil (spermaceti wax), from the head of the sperm
whale, which is composed of cetyl palmitate.
Waxes are insoluble in water, and not as easily hydrolyzed as fats and
oils. They often occur in nature as protective coatings on feathers, fur,
skin, leaves, and fruits.
Sebum, secreted by the sebaceous glands of the skin, contains waxes
that help to keep skin soft and prevent dehydration.
Waxes are used commercially to make cosmetics, candles, ointments,
and protective polishes.
Since we are already familiar on what nonglycerides are, we will proceed to the
fourth and the last class of lipids called Complex lipids.
COMPLEX LIPIDS (LIPOPROTEIN)
Complex lipids are lipids that are bonded to other types of molecules. The most
common and important complex lipids are plasma lipoproteins, which are responsible
for the transport of other lipids in the body.
Lipids are only sparingly soluble in water, and the movement of lipids from one
organ to another through the bloodstream requires a transport system that uses plasma
lipoproteins. Lipoprotein particles consist of a core of hydrophobic lipids surrounded by
amphipathic proteins, phospholipids, and cholesterol.
27
Lipoproteins are classified according to density.
High protein to phospholipid ratio = high density.
Low protein to phospholipid ratio = low density.
1. Chylomicrons- the lowest DL, transports dietary triglyceride from the gut to the
liver, adipose tissue and muscle. They appear in the bloodstream after a meal
and transport dietary triglycerides from the gut to sites where the triglycerides are
used and stored.
2. Very low-density lipoproteins (VLDL). They transport triglycerides and
cholesterol that are synthesized by the liver to similar sites for utilization or
storage. Many people with high triglycerides and cholesterol make too much
VLDL in the liver because of an inherited tendency. Transports mostly
triglyceride, some cholesterol, from liver to the periphery. When chylomicrons
and VLDL reach capillary beds in various tissues such as muscle or fat, an
enzyme breaks down triglycerides into fatty acids and glycerol. The remaining
chylomicron remnants continue to circulate until they are taken up or absorbed
by the liver.
- Low HDL and high LDL levels in the blood are warning signs of
atherosclerosis, the buildup of cholesterol-containing deposits in arteries.
28
Now you know that having too much or too little of cholesterol have adverse
effects on our health so it is important to have healthy lifestyle to prevent such health
deficiencies.
Activities
Answer in a separate sheet of paper.
1. What are steroids? Is it safe to take steroids? What are the long-term effects of
steroids?
2. What is a Lipid profile? Is it important to know your lipid profile? Why or why not?
Assessment
Multiple Choice: Select the correct answer from the given choices. Write your answer in a
separate sheet of paper.
1. Which of the following types of wax is an ester formed by combining palmitic acid with a
30-carbon alcohol.
A. Beeswax B. ear wax C. natural wax D. Paraffin wax
2. Most waxes are
A. Hydrophilic B. hydrophobic C. polar D. soluble in water
3. Which of the following types of wax is generally composed of a long-chain fatty acid
esterified to a long-chain alcohol.
A. Beeswax B. earwax C. natural wax D. Paraffin wax
4. This condition occurs when cholesterol levels are too high and precipitates or the levels
of bile salts is too low
A. Anemia B. Atherosclerosis C. Gallstones D. Hypertension
5. What is the most abundant steroid in the body?
A. adrenocorticoid B. Bile salts C. Cholesterol D. vitamin D
6. These are type of sphingolipids that contain carbohydrates, usually monosaccharides.
A. cerebrosides B. Glycolipids C. isoprenoids D. Sphingomyelins
7. These are a type of lipids made up of fatty acid chains that are not derived from glycerol.
A. Complex lipids B. Glycolipids C. Phospholipids D. Sphingolipids
c. APPLICATION
To organize your understanding about lipids, draw, color and fill up the missing part
on the concept map below.
29
Source: https://sciencemusicvideos.com/ap-biology/module-6-menu-biochemistry/biochemistry-3-lipids-interactive-tutorial/
d. GENERALIZATION
Sphingolipids are a type of lipids made up of fatty acid chains. Like phospholipids,
sphingolipids are amphipathic, having a polar head group and two nonpolar fatty acid
tails, and are structural components of cellular membranes.
Cholesterol is an essential component of cell membranes, and is a precursor for other
steroids, such as the bile salts, sex hormones, vitamin D, and the adrenocorticoid
hormones.
Steroid hormones are made from cholesterol and are secreted by three
“steroid glands”—the adrenal cortex, testes, and ovaries—and during pregnancy by the
placenta.
Bile salts are made of bile acids that are conjugated with glycine or taurine. They are
produced in the liver, directly from cholesterol
Gallstones can block the duct that allows bile to be secreted into the duodenum. Fats are
no longer digested properly, and bile pigments absorbed into the blood causes the skin to
become yellow and the stool to become gray.
Waxes are derived from many different sources and have a variety of chemical
compositions, depending on the source.
Complex lipids are lipids that are bonded to other types of molecules. The most common
and important complex lipids are plasma lipoproteins, which are responsible for the
transport of other lipids in the body.
e. POST ASSESSMENT
Multiple Choice. Analyze each question carefully then choose the letter of the correct
answer. Write the letter of your answer in your sheet of paper.
1. What is the primary lipoprotein secreted from the liver that is at least partially composed
of dietary derived lipids?
30
A. ceramide B. lecithin C. Sphingomyelins D. sphingosine
10. Which of the following compound cholesterol does not serve as a precursor?
A. Bile pigments B. Bile salts C. Vitamin D. Sex hormones
31
Answer Key Lesson 2- FATTY ACIDS & GLYCERIDES
ACTIVITIES
Lesson 1- Properties of Lipids
1. caproic acid-
Assessment SATURATED
Activities 1. Nonpolar, 2. lauric acid –
Pre- POST SATURATED
1. Yes. nonpolar, insoluble
Assessment 1. C 3. butyric acid–
Lipids are orga 2. fatty acids, oxygen
nic molecules 3. liver
1. TRUE 2. D SATURATED
composed 4. specific gravity 2. FALSE 3. B 4. UNSATURATED
of carbon, 5. oxidative rancidity 3. FALSE 4. A 5. SATURATED
hydrogen, and 6. saturated 4. FALSE 5. D
oxygen atoms. and/or unsaturated 5. FALSE 6. B Pre
2. carbon, fatty acids. 6. TRUE Assessment
7. C Assessment
hydrogen, and 7. Glycerol 1. A 1. A
7. TRUE 8. C
oxygen atoms. 8. sodium or 2. C 2. A
8. TRUE 9. A
3. A. unsaturated potassium salts, 3. A 3. A
B. saturated saponification. 9. FALSE 10. D 4. B 4. A
4. Refer to the 9. fats. 10. FALSE 5. A 5. B
module on 10. emulsification. 6. A 6. B
properties of 7. A 7. B
lipids 8. D
9. B
10. D
Lesson 3- Nonglycerides & Complex Lipids
PRE- ASSESSMENT
ASSESSMENT APPLICATION POST- L2- POST
Assessment
1. D 1. A 1. Sphingom ASSESSMENT
1. B
2. D 2. B yelin 1. C 2. D
3. B 3. D 2. Chylomicr 2. C 3. C
4. B 4. B ons 3. D 4. C
5. B 4. C 5. A
5. B 3. Waxes
6. C 5. B 6. C
6. C 4. Polar
7. D 7. C group 6. D
8. C 5. LDL’s 7. B
9. C 8. C
10. D 9. D
10. A
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References
Davis, Raymond E., Frey, Regina, Sarquis, Mickey, Sarquis Jerry L. (2009). Modern Chemistry (Teacher’s edition)
Holt, Rinehart and Winston, USA
LeMay, Jr. Eugene H., et al. (2000). Chemistry Connections to Our Changing World (Teacher’s Edition) Prentice Hall,
Inc. Upper Saddle River, NJ 07458
Electronic Sources:
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n.d. Accessed 12 July 2020
https://www.youtube.com/watch?v=wnK1Kv3XkZI
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