L18 Cranial Nerves

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L18 Cranial nerves


LEARNING OBJECTIVES

Learn names and locations of 12 cranial nerves

Understand functions of cranial nerves

Broad locations of cranial nerve nuclei and into to central connections

Learn common lesions associated with cranial nerve dysfunction

Cranial nerves
There are 12 pairs of cranial nerves
C.I Olfactory
C.II Optic
C.III Oculomotor
C.IV Trochlear
C.V Trigeminal
C.VI Abducens
C.VII Facial
C.VIII Vestibulocochlear
C.IX Glossopharyngeal
C.X Vagus
C.XI Spinal Accessory
C.XII Hypoglossal
Oflactory nerves are located outside the brain.
The trochlear nerve exits from dorsal side, all the rest exit from ventro lateral side
Cranial nerve functions are extremely well conserved among vertebrates. There are some cranial nerves associated with diencephalon
Olfactory nerve (C.I)
Carries special sensory info responsible for smell. Synapse within olfactory bulb.
Optic nerve (C.II)
Special sensory nerve of vision. Retina is in the CNS, optic nerve project back to optic chiasma. Partial decussate. Retina divided into two, nasal retina and temporal
retina. After the chiasma the optic nerve is called the optic tract. This is important because if there is a lesion of the left optical nerve it would affect the left eye. If the optic
tract is lesioned then sight is lost in both eyes as information is received from both eyes.
Oculomotor, Trochlear. Abducens (C.III, IV, VI)
Oculomotor nerve (C.III)

Somatomotor - Primary source of innervation for 4 of eye extraocular muscles

Parasympathetic - Pupillary muscle (constrict pupil in light reflex) and ciliary muscle (accomodation reflex)

Trochlear nerve (C.IV)

Innervates superior oblique muscle allowing eye to move eye down and out

Abducens nerve (C.VI)

Eyeball movement from side to side

Trigeminal (C.V)

Motor nucleus (muscles of mastication (for chewing))

Spinal nucleus (sensory) for pain and temp from head and neck

Principal nucleus (sensory) for touch and vibration

Mesencephalic nucleus for jaw reflexes

Facial (C.VII)

Motor - muscles of facial expression (mimetic muscles)

Sensory - Skin of external auditory meatus (outer canal of ear), eardrum

Special sensory - taste (anterior 2/3 of tongue), palate

Parasympathetic innervation of salivary glands and lacrimal glands involved in crying (NOT parotid in cheeks)

Vestibulocochlear (C.VIII)
Vestibular branch monitors balance, position and movement
Cochlear branch monitors hearing

Glossopharyngeal (C.IX)

Special sensory - taste in posterior 1/3 of tongue

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Visceral sensory - blood pCO2/ H+ monitoring (carotid body)

Sensory - Posterior 1/3 of tongue, oropharynx

Motor - Upper pharynx

Parasympathetic - parotid gland

Vagus (C.X)
A mixed sensory and motor nerve which is the MAIN parasympathetic nerve)
Sensory

Somatosensory

Mucus membranes of laryngopharynx, larynx and upper trachea

Visceral

Trachea, lungs, carotid sinus, abdominal veins, gut

Motor

Somatic

lower pharynx, upper oesophagus (swallowing and vomiting)

Parasympathetic

Cardiac muscle (depressing HR), smooth muscle in GIT (GI motility) trachea and bronchi (airway diameter)

Spinal accessory (C.XI)


Spinal accessory nerves are motor nerves. Have roots in cervical segments of spinal cord. Roots travel up through foramen magnum and join cranial fibres to form
accessory nerve which then pass through jugular foramen to carry somatic motor information to skeletal muscles of neck and upper back.
Innervation of muscles associated with shoulder and head movement eg. sternocleidomastoid and trapezius
There is probably only a spinal root of C.XI Early texts refer to a cranial root but these are now thought to be aberrant fibres of C.X

Hypoglossal (C.XII)

Motor

Intrinsic muscles of tongue

Most extrinsic tongue muscles

Lesions
Lesions of nerves supplying facial muscles
UMN vs LMN (Upper motor neuron vs Lower motor neuron)

UMN
UMN lesion of facial muscles, the upper face is fine because BOTH hemispheres contribute to movement of upper face. So unaffected hemisphere can compensate.

Lesions involve face area of primary motor cortex or descending corticobulbar fibers.

Called Central facial palsy or Corticobulbar palsy

LMN
LMN lesion to C.VII, the ENTIRE face is affected on one side

Lesions involved the motor facial nucles or facial nerve in pons, cranial cavity, middle cavity or on its course of peripheral distribution

Called Peripheral face palsy or Bells palsy

Cranial nerve nuclei


Oculomotor nucleus is in midbrain

Trigeminal nucleus extends midbrain through pons down to medulla


Vestibular and cochlear nuclei

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