PhysioEx Exercise 11 Activity 2
PhysioEx Exercise 11 Activity 2
PhysioEx Exercise 11 Activity 2
2 The ESR cannot be used to follow the progression of which of the following diseases?
Experiment Results
Predict Question
1 Predict Question: How will the sedimentation rate for sample 6 (individual with angina
pectoris) compare with the sedimentation rate for sample 1 (healthy individual)?
Experiment Data
Blood Distance RBCs have settled Time Sedimentation rate
sample (mm) elapsed (min) (mm/hr)
1 5 60 5
2 15 60 15
3 0 60 0
4 30 60 30
5 40 60 40
6 5 60 5
Your answer: the settling of plasma in a vertical, stationary tube of whole blood during
one hour.
Correct answer: the settling of RBCs in a vertical, stationary tube of whole blood during
one hour.
Your answer:
sickle cell anemia is a blood disorder witnessed by improper folding of hemoglobin
when hemoglobin levels are low and affects the oxygen carrying capacity of an
individual. ESR is the time taken for the erythrocytes to settle in a period of 1 hour.
Sickle cell shows no impact on ESR because sickle cell anemia alters the shape of the
red blood cells and leads to
faster clumping of cells and faster settling.
2 How did the sedimentation rate for the menstruating female (sample 2) compare with
the sedimentation rate for the healthy individual (sample 1)? Why do you think this
occurs?
Your answer:
3 How did the sedimentation rate for the individual with angina pectoris (sample 6)
compare with the sedimentation rate for the healthy individual (sample 1)? Why? How
well did the results compare with your prediction?
Your answer:
4 What effect does iron-deficiency anemia (sample 4) have on the sedimentation rate?
Your answer:
Iron deficiency anemia increases the sedimentation rate. Decreased iron content in
blood increases the setting time as the cells become much lighter.
5 Compare the sedimentation rate for the individual suffering a myocardial infarction
(sample 5) with the sedimentation rate for the individual with angina pectoris (sample
6). Explain how you might use this data to monitor heart conditions.
Your answer: