Medicine in Ancient Egypt
Medicine in Ancient Egypt
Medicine in Ancient Egypt
practicaban la amputación de extremidades y además In particular, the Old Kingdom period is known
la circuncisión. Estudios de biología molecular as the Age of the Pyramids (1). One of the most
demuestran la existencia de tuberculosis, malaria, powerful pharaohs of this period was Zoser or
esquistosomiasis, teniasis y ascaridiasis. Se demuestra Djoser (second pharaoh of the III dynasty) who
que padecían de aterosclerosis, caries dentales y
ruled from 2665 to 2645 b.C, established the
otros padecimientos odontológicos. El cáncer era
infrecuente. Las hierbas, sustancias de origen vegetal capital of the empire in Memphis, south of the Nile
(aceites, resinas, etc.) o minerales formaron parte de delta, and ordered the construction of the famous
la farmacopea egipcia antigua. Existía un sistema stepped pyramid of Saqqara, the first large-scale
bien establecido de atención médica, asociado con stone construction that would serve as eternal
una jerarquía bien definida. rest. This was designed by the sage Imhotep,
who in addition to being an architect, was a
Palabras clave: Antiguo Egipto, papiros médicos, renowned physician who lived between 2690
papiro de Lahun, papiro de Ebers, papiro de Edwin and 2610 b.C (Figure 1). He was an important
Smith, momificación.
person, occupying the positions of the high priest
of Heliopolis and chay of the pharaoh (chay or
HISTORICAL INTRODUCTION vizier is the royal official of the highest degree
in the court). A commoner by birth, Imhotep’s
According to the criteria of most historians, the intelligence and determination enabled him to
expression Ancient Egypt refers to the civilization become Djoser’s most trusted advisor (1). After
that flourished along the Nile in the long period of his death, he was deified as the god of medicine
about 2 800 years that ends with the conquest of and wisdom, his main cult being in Memphis
Alexander the Great in 332 b.C. Some historians and Thebes.
also include the Greek or Hellenistic period that
elapsed between 332 and 30 b.C, when Egypt
became a province of the Roman Empire (1). In
general, according to conventional chronology,
ancient Egyptian history comprises 26 dynasties
grouped into the following periods:
1. Predynastic period (5000 - 3100 b.C)
2. Early dynastic (Dynasties I and II; 3100-2686
b.C)
3. Old Kingdom (Dynasties III to VIII; 2686-
2160 b.C)
4. First intermediate period (Dynasties IX to XI;
2160 - 2055 b.C)
5. Middle Kingdom (Dynasties XII to XIV; 2055
- 1650 b.C) Figure 1. Imhotep representation.
6. Second intermediate period (Dynasties XV to
XVII; 1650 - 1550 b.C)
7. New Kingdom (17th to 20th Dynasties; 1550
- 1069 b.C) DOCUMENTARY SOURCES
8. Third intermediate period (Dynasties XXI to The documentary sources of Ancient Egyptian
XXV; 1069 - 664 b.C) medicine are found mainly in the so-called
9. Late period (XXVI Dynasty and Persian rule; medical papyri, in the hieroglyphic writings found
664 - 332 b.C) in monuments, temples, tombs, and sarcophagi,
and in the accompanying drawings (1,2). These
sources are complemented by paleopathographic
or paleodiagnostic studies, carried out with
Figure 2. Fragment of the Lahum papyrus (left) and squat delivery engraved on a wall of the Kom Ombo temple (right).
THE EDWIN SMITH PAPYRUS (The sugar in the honey exerts an osmotic effect
and drains fluids from the wound and bacteria
The Edwin Smith papyrus, purchased by his do not grow on the honey). In other cases,
eponymous from an Egyptian merchant, has been surgical sutures, cauterization, splints, crutches,
dated to around 1550 b.C. It is considered the and supports were used to keep the patient erect.
oldest surgical book in the world (5-7). Its 17 Wound complications, including infection and
pages describe 48 surgical cases, most of them tetanus, are also described. As a treatment for
traumatic (fractures, dislocations, wounds), but a bleeding nose fracture, they used oil-soaked
also include observations on tumors, ulcers, linen swabs in each nostril or placed a rigid roll
abscesses, and their consequences (Figure of linen, followed by a bandage. Treatment for
3). The presentation is organized in the form clavicle and humerus fractures and reduction in
of a clinical history, where the location of the jaw dislocation are described. Smith et al. in
disease, the diagnosis, and the treatment are 1908 studied 2 mummies from V Dynasty tombs
systematically indicated (except in fatal cases). at Naga-ed-dêr with wooden splints preserved
Physiological processes such as blood return, in situ; the patients apparently died due to open
the nervous system, and the importance of the fractures (Smith 1908), one with a compound
spine as a center of control and movement are fracture of the femur treated with wooden splints
described. Methods of fracture and dislocation and another with a compound fracture of the
reduction and procedures for their containment forearm with wood bark splints. For pain, fever,
are described for the first time. The reduction of and inflammation, it mentions the decoction of
jaw dislocation is described in much the same way willow bark (giving origin after several centuries
as it is currently done. Instructions are given for to aspirin). Precise anatomical and medical terms
patients with open head wounds with an exposed such as brain, meninges, fracture, and seizure are
brain (the brain is macroscopically described with mentioned for the first time. This medical text
corrugations such as those that form in molten contains detailed anatomical observations, but
copper and somewhat softened); if blood flows shows no understanding of organ functions, along
from the nostrils and there is neck stiffness, the with the oldest known reference to breast cancer.
recommendation is that these patients should It is currently kept at the New York Academy of
not be treated. They describe complications Medicine. In summary, the text of the Edwin
after a stroke such as dragging gait or foot drop. Smith papyrus is based on the observation,
The meningeal irritation in cases of meningitis collection, and classification of the facts and
is described in the form of “stiffness” of the the application of an inductive mental process,
neck or the inability of patients to “look at their exposing the emerging surgical semiology and
shoulders”. contains a vision of the clinic, of the anatomy,
Regarding wounds and lacerations: the first of the physiology as well as the pathology and
day they were treated with bandages and dressings treatment prevalent at that time (2,5-7).
made of fresh meat and then with oil and honey
Figure 3. Fragment of the Edwin Smith papyrus (left; available at http://archive.nlh.gov.), and Edwin Smith oil painting
by Francesco Anelli, from the collection of the New-York Historical Society (right).
THE EBERS PAPYRUS a laxative: castor oil, figs, and dates. Infestation
with tapeworms was treated with an infusion
The Ebers Papyrus, the best known and most of pomegranate root (it is known now that the
extensive of the Egyptian medical papyri, is in the alkaloids present in this infusion paralyze the
Library of the University of Leipzig. Its name nervous system of the tapeworm and promote its
comes from the German Egyptologist George expulsion). Ulcers and stomach ailments were
Moritz Ebers, who acquired it in 1872; It is 20.25 treated with yeast. Cases of ocular pathology
m long and 30 cm wide with 108 columns or are mentioned: chalazion and stye, blindness,
pages, each containing 20-22 lines of hieratic trachoma, pterygium, blepharitis, ectropion,
writing (8). It was written around 1536 b.C. in the trichinosis, ocular hemorrhages, corneal
reign of Amenhotep I (18th Dynasty), it contains leukoma, corneal ulcers and scars, cataracts, and
877 sections on medicine with mention of some conjunctivitis. Figure 4 shows the painting of a
700 drugs. It deals with diseases of the eyes, of doctor extracting a supposed foreign body from
the skin, of the extremities, and the respiratory, the eye of a patient with an ophthalmological
digestive, and urinary systems, as well as the first instrument. This is the treatment of a labor
sketch of clinical depression and dementia and of problem, and it must have occurred frequently
the various treatments of these affections, which in the workers who built the pyramids, temples,
in many cases include religious invocations. and monuments. The painting is in the tomb
Some of the plant products mentioned in of the sculptor Ipuy, in Deir el-Medina located
the Ebers papyrus for their medicinal effect south of Sheikh Abd el Qurna. The sculptor of
are saffron, myrrh, aloe, castor leaves, lily Ramses II captured a series of scenes of what
extract, poppy juice, coniferous resin, hemp, today we understand as work accidents in the
and frankincense. Raw garlic was prescribed catafalque of Ipuy.
for asthma and bronchopulmonary conditions, Regarding treatments with drugs of mineral
onions to treat gastrointestinal problems and for origin, natron (a mineral formed by sodium
colds, coriander against flatulence and cystitis, carbonate and bicarbonate and sodium sulfate
cumin against flatulence and in a poultice with and chloride), common salt, malachite, and lapis
wheat flour and water against joint pain, cumin lazuli are mentioned; the latter is not absorbed,
with lard as an anal suppository for anal itching, and its use was restricted to ocular pathologies (8).
basil for the heart, aloe for parasites, belladonna
for insomnia and pain, colchicine for rheumatism,
cardamom as a digestive, and garlic and onion
to increase physical strength. The leaves of
many plants, such as willow, sycamore, and
acacia, and tree resins were used in poultices.
The papyrus also mentioned drug treatments
of animal origin such as honey, milk, blood,
urine, placenta, bile, fat, meat, and liver extract;
animal excrement from cats, birds, crocodiles,
and also human excrement was used in medical
treatments. Honey was mainly for internal use
although was also recommended for the treatment
of open wounds for its anti-inflammatory and
healing effect. One remedy for gray hair was
an extract of cat’s placenta, and fat from lion,
hippopotamus, crocodile, cat, snake, and other Figure 4. Physician extracting a foreign body from the eye
animals were prescribed against baldness. Animal of a patient (painting on the catafalque of Ipuy, a sculptor,
fat was also used to make ointments in the hope in Deir el-Medina).
of transferring some desirable characteristics
of the animal. Ass penis prepared as a powder
is mentioned for the treatment of impotence (a
precursor to today’s Viagra). They are used as
THE BROOKLIN PAPYRUS Zaki et al. in 2010 studied 204 skeletons and
2 287 long bones from the Giza Cemetery and
The Brooklyn Papyrus is a medical papyrus found a mummy with limb amputation dating
dealing with medicine and ophidiology; it has from the III-VI Dynasty (2700-2190 BC) and the
been dated around 450 b.C and is preserved second case of another skeleton with ulna and
in the Brooklyn Museum in New York. It radius amputation (10). It is interesting to note
describes 21 snakes, their characteristics, habits, that in the temple of Edfu (dedicated to Horus,
the appearance of the bite, and its effects, such equivalent to the Greek Apollo), located in the
as fever for 7 to 11 days, weakness, tremors, homonymous city that was known as Apolinópolis
tetanization, eye muscle spasms, bleeding, and Magna during the Hellenistic period, a bas-relief
inflammation. The papyrus also describes the represents the amputation of a leg as a testimony
prognosis of patients according to the species to the practice of this surgical method in Ancient
of snake involved. Survival was conditioned Egypt (Figura 5). This temple is the second largest
by the number of days after the bite and the temple in Egypt after that of Karnak and one of
treatment. Uncontrollable emesis was a sign the best-preserved. In the Egyptian Museum of
of poor prognosis. The treatment was usually Cairo, a prosthesis that replaces the big toe of a
local with drugs, herbs, and spells, incision of the foot, found in Thebes, in the year 2000 is exhibited
wound with a knife several times the first day to (Figure 6). The skull of Pharaoh Seqenenrade of
remove necrotic tissue and alleviate the edema, the 17th Dynasty from 1600 b.C is also exhibited
and then they applied salt or natron and bandage. there. The skull shows a perforation. By using
The onion was widely used, associated with an X-rays, it was shown that there was bone growth
invocation to Horus, God of Heaven, and the around the perforation indicating that the pharaoh
origin of life; they also invoked Serket, goddess lived at least several months after the accident,
of scorpions with powers over snakebites (2). probably treated by doctors (Figure 7).
Open wounds were often treated with honey,
but sepsis was one of the most common causes
of death (2).
Figure 8. Surgical instruments from Ancient Egypt were carved into the Kom Ombo temple wall (left) and temple facade
(right).
amputation as medical treatment in ancient Egypt. 26. Ruffer MA. Remarks on the Histology of Pathological
Int J Osteoarcheol. 2010;20(4):405-423. Anatomy of Egyptian Mummies. Cairo Publishing
10. Zaki ME, Sarry ME, Sarry El-Din AM, Al-Tohamy Committee, Cairo, Egypt; 1910.
SM, Mahmoud NH, Baker Basha WA. Limb 27. Atiya F, El-Shahawy A, al-Misri M, Atiya F. The
Amputation in Ancient Egyptians from Old Kingdom. Egyptian Museum in Cairo: A walk through the alleys
J App Sci Res. 2010;6(8):913-917. of ancient Egypt. Cairo, Egypt: Farid Atiya Press;
11. Feucht E. Pharaonic Circumcision. En: Sibylle Meyer, 2005:75-76.
editor. 2010: Egypt - Temple of the Whole World; 28. Kozma C. Dwarfs in ancient Egypt. Am J Med.
Leiden, Países Bajos; 2004.p.718-729. Genet Part A. 2005;140A(4):303-311.
12. Brier B. Infectious diseases in ancient Egypt. Infect 29. Dawson WR Pygmies and dwarfs in ancient Egypt.
Dis Clin North Amer. 2004;18(1):17-27. J. Egyptian Archaeol. 1938;24(2):185-189.
13. Bartels P. Tuberkulose in der Jüngeren Steinzeit. Arch 30. Thompson RC, Allam AH, Lombardi GP, Wann LS,
Anthropol. 1907;6:243-250. Sutherland JD. Atherosclerosis across 4000 years
14. Buikstra AE, Baker BJ, Cook DC. What diseases of human history: The Horus study of four ancient
plagued the ancient Egyptians? A Century of populations. Lancet. 2013;381(9873):1211-1222.
controversy considered. En: Davies WV, Walker R, 31. Allan AH, Thompson RC, Wann LS, Miyamoto MI,
editors. Biological anthropology and the study of Thomas GS. Computed tomographic assessment of
Ancient Egypt. London, UK: British Museum Press; atherosclerosis in ancient Egyptian mummies. JAMA.
1993.p.231-250. 2009;302:2091-2094.
15. Cave AJE. The evidence for the incidence of 32. Ruffer MA. On arterial lesions found in Egyptian
tuberculosis in ancient Egypt. Br J Tubercol. mummies (1580 BC–525 AD). J Pathol Bacteriol.
1939;33:142-152. 1911;15:453-462.
16. Ziskind B, Halioua B. Tuberculosis in ancient Egypt. 33. David AR, Kershaw A, Heagerty A. The art of
Rev Mal Resp. 2007;24(10):1277-1283. Medicine. Atherosclerosis and diet in ancient Egypt.
17. Deelder AM, Miller RL, De Jonge N, Krijger FW. Lancet. 2010;375(9716):718-719.
Detection of schistosome antigen in mummies. Lancet. 34. Schwarz JC. La médecine dentaire dans l’Égypte
1990;335(8691):724-725. pharaonique. Bulletin de la Société d’Égyptologie.
18. Miller RL, Armelagos GJ, Ikram S, De Jonge N, 1979;2:37-43.
Krijger FW, Deelder A. Palaeoepidemiology of 35. Ghaliounghui P. The Physician of Pharaonic Egypt.
Schistosoma infection in mummies. Brit Med J. Al-Ahram Center for Scientific Translation. Cairo,
1992;304(6826):555-556. Egypt. 1983.
19. Ziskind B. Urinary schistosomiasis in ancient Egypt. 36. Muller A. La medicina en el antiguo Egipto. Soc Ven
Nephrol Ther. 2009;5:658-661. Hist Med. 2019;68(1-2).
20. Di Bella Stefano, Riccardi N, Giaccobbe, Luzzatti R. 37. Andrews C. Egyptian Mummies. London: British
History of schistosomiasis (bilharziasis) in humans: Museum; 1984.
From Egyptian medical papyri to molecular biology 38. Brier B. Egyptian Mummies: Unraveling the Secrets
on mummies. Pathol Glob Health. 2018;112(5):268- of an Ancient Art. New York: William Morrow; 1994.
273.
39. Struwick H. The Ka, the Ba and the Akh. History. The
21. Nerlich AG, Schraut B, Dittrich S, Jelinek T, Zink AR. Encyclopedia of Ancient Egypt, New York; 2006:178.
Plasmodium falciparum in Ancient Egypt. Emerg
40. Ikram S. Death and Burial in Ancient Egypt. The
Infect Dis. 2008;14(8):1317-1319.
American University in Cairo Press. Cairo, New
22. Strouhal E. Traces of smallpox epidemic in the York; 2013.
family of Ramesses V of the Egyptian 20th dynasty.
41. Ikram S, Dodson A. The Mummy in Ancient Egypt.
Antropologie. 1996;34(3):315-319.
London: Thames and Hudson; 1998.
23. Otsuji Y. History, epidemiology and control of
42. Aufderheide AC. The Scientific Study of Mummies.
filariasis. Trop Med Health. 2011;39(1 Suppl 2):3-13.
Cambridge University Press. Cambridge; 2003.
24. Cockburn A, Cockburn E, Reyman, TA. Mummies,
43. Caminos R A. On ancient Egyptian mummy bandages.
Disease, and Ancient Cultures. 2nd edition. Cambridge:
Orientalia. 1992;6l:337-353.
Cambridge University Press; 1998.
44. Müller A. Vida después de la vida: muerte,
25. Valet JS. Las enfermedades respiratorias en el Antiguo
momificación y entierros en el Egipto Antiguo. Rev
Egipto. Arch Bronconeumol. 1994;30:506.
Soc Ven Hist Med. 2017;66(1-2).