HomEOBOx GENES PAGE No
DATE
CoNTENTS
-INTRODUCTCoN
DTSCOVERY
HOMIG 00 0MACN
Hox GGNES
FUNCTLONS
CoNCUv rON
KEP ERENLES
NTRo DUCTCON
at
i a wm ffmalion
a9einhc Clhoneuhorshc
enio des
Jang a
oa similan
Homeoboy 9enen a
t d i r e u t and ryulE Lu fomndlew
hedy sruu t i m embr
llepmud
anond 8o bae
Hemee h ex w _a ONA Sequmue
pour Jmy fnvalnd r2}liow o
paterna toic sl deuelopna whhojewm)_
Odmal fu ad plac.
DISCOVERY=_
Homesbo xe dukcovemd ndepadotly in
1983 b: Ernat Hafen, Michael heuinednd
LiriliouMeGinnin Bakel MeGinnin ed nau)
Qnd Scodt nA wetne SY n Bloo inton
Thm n
n t discoweud rut (Drsofhila
PAGE No 2
DATE
And Suh &e que ly m bLer OdnukmA
Homeodomoin-
Hemeebox qms Con-alJn a 180 bn our
DNA Sewomu
povidus fer maletv
Unent
amino au n buIAi
bloek
Homcodemain auk_a ramsunphon ture
Bnd DNAand cowhols tramlenpHm
ColA
-Cnii oke patew o Tmiom
H tranicnphm euhrs orrlae cspeue
ames s axi aina
emhr
Hox
T hahom oneure irest menenhamd
reus b Auurad hmu rHuated
POx
r Cronds euta dunolope m u d t
HO A Hox B2 MSx!
Hox A2 Hox B Wnt e B t
PAGENo
T
3
DATE
in mgraB
mgrah
a expencd
Hox 9 chut
e callu ow
heur Cyent
Onginaka
TMLD RRALN
Hnd.Hind by ain
RaR KGKR4 R3 R2 k1
83
3A 4- 8A3
BA2 BAI
Cret exm e
Arch I o populaed _ww
a dR L R 2
yposeiY meneniephoalon
2 No
Arch - wh iu bobled n u l l cotot +
and Jho miear Conhmbuttomro aud
Rs exllnes ox-2
ols _expr HOX-2 and O-3
Aruh IV-VI mAo fndiy clualnd
90p epulaed emembally b9 R
nd U Crtte yMp Ho 2 d
Hox 3
PAGE No
DATE
Hox 9em netnwonnd
anlt bramduid
m2 0tx-1 od
0tx-2 patt exniny r l auten 94in
Lad
Anuber o o 9 OnL
e vwM in
Mai a mad- a and deur opi
u d brimar duod Onn
h u fnilueu MCx MS-2, DLX -6
BARX-1 ond ET-L
MSX -1nd MSX-2 a a shaub role
speuhcahon sku and aue
DIAphcn MSA , MSX -2 n 2aperimon
aimaln d Jd LoAs gpalahoe Shelw
Aoenepalahiu bon moax and maud
Defeehve exprsim MSy 2 Case o u tin
Skul O hin
DLA-- monn Coo h J poximal a
Ave her M Dmehon hon genn
0DAe Coid Enclottnalin- _(ET-1).
rAGE No
DAT
Co Y Vanoauuhve pebhida
o a a galhm blond
remu
CVs anamOun
reduch'on n tongw e
Micogn i e 2 ceft pa
SonicHedgocg e aneer poHein
a Mpatandv
neuyad bake
Deehnwhatttni haloprOAeneph
OLl wre o avastJn l nwd i n
nd o p i a
Cm c tm
ome hexqew a a y mbeet nom
mphesewriz n alnimo fuuneli umaw
Murahows o w qr0 ee lad n
apnevnmed shturu
Refor
(T McainnitN, Levins , Haen E, kuoiwa A,
ehi w
(118u ACongev DNA cequtme
Jhimoeohc ens Dso«dpila Amtenn
Cpodia and bi x Complxs Naun 308
59S8) u28-33
Teect bore k. yawioheuiel ro Smdhav emhu
