Patterns of Eye Diseases Among Children
Patterns of Eye Diseases Among Children
Patterns of Eye Diseases Among Children
https://www.scirp.org/journal/ojoph
ISSN Online: 2165-7416
ISSN Print: 2165-7408
to 12 years respectively. Males had higher eye disease frequencies than fe-
males. Results show a downward trend in the number of children who present
with eye conditions per year under study. In 2018, frequency of eye conditions
was 56.1% while in 2019, it was 33% and lastly, 10.9% in 2020.
Keywords
Blindness, Visual Impairment, Childhood, Visual Acuity
2. Research Methodology
2.1. Study Design
A hospital-based retrospective study aimed at ascertaining the profile of child-
hood eye conditions was conducted in Harare and Bulawayo. Hospital archived
data of patients aged 15 years and below presenting at Richard Morris Hospital
in Bulawayo and Sekuru Kaguvi Eye Hospital in Harare between 1 January 2018
and 30 September 2020, were electronically retrieved and retrospectively re-
viewed. This review was quantitative in its orientation. The study protocol and
ethical considerations were obtained and approved by the Medical Research
Council of Zimbabwe, Regulatory Authority reference number MRCZ/E/291. All
the data was anonymous to protect the identity of the patients in the study. In
each of the study sites, data was extracted by ophthalmic nurses trained in data
extraction and research ethics and the trained nurses were supervised by the
ophthalmologists in their respective centres with a biostatistician and research
methodologists from the University of Zimbabwe who provided technical back-
stopping.
3. Results
3.1. Demography of the Participants
All the 10,066 patient records between January 2018 to September 2020 were ex-
tracted from Sekuru Kaguvi and Richard Morris eye clinic registers and sub-
sequently reviewed.
There were 4785 (47.5%) from the Bulawayo records and 5281 (52.5%) from
the Harare records. The median age of the children attending both eye hospitals
was 5years old and the range was 2 to 15 years old. The demographic profile of
the patients in the study is presented in Table 1 below.
Center
Bulawayo 4785 (47.5)
Harare 5 81 (52.5)
Gender
Female 4360 (43.3)
Male 5706 (56.7)
From Figure 1 above, it can be noted that allergic conjunctivitis was the most
frequent eye condition totaling 2422 and constituted 24.1% of the study popula-
tion. This was followed by eye injury, 1499 (14.9%), lid pathology, 911 (9.1%) and
refractive error, 827 (8.2%). The most frequent eye conditions found in children
seeking hospital care were allergic conjunctivitis, eye injuries, lid pathology, re-
fractive error, ocular surface disease, corneal disease, cataract, ophthalmia neo-
natorum, squint, and aphakia.
The frequency of retinoblastoma was 99/10,066 (0.098%). When compared by
site, SKH had more patients who were diagnosed with retinoblastoma (72 SKH;
27 RM). However, Richard Morris had more patients diagnosed with ophthalmia
neonatorum (8 SKH; 469 RMH) conditions.
The study also sought to subclassify the eye conditions in relation to the late-
rality of the eye involved. The results for these trends are presented on Table 2
below. Data was grouped according to the nature or pattern of the condition.
From Table 2 below, almost half 4969 (49.4%) of the patients’ data was rec-
orded as missing and thus, did not reveal the exact eye that was affected. 2959
(29.5%) had both eyes affected, while 1102 (11%) had the right eye affected and
1036 (10.3%) had the left eye affected.
Eye conditions that were most common in the ages 6 to 12 were uveitis, ante-
rior segment disease, aphakia, corneal diseases, refractive error, and eye injuries.
However, there were no conditions that were only peculiar to the 13 to 15 age
group.
Table 3 below shows a 95% Confidence Interval falling between (1.46) lower
bound and (1.49) upper bound for the 0-5 age group on the diagnosis of eye
conditions variable. On the 6 - 12 age group, the 95% CI is between (1.45) lower
limit and (1.48) upper limit on the same variable. For the 13 - 15 age group, the
95% CI for diagnosis of eye conditions is between (1.46) lower bound and (1.52)
upper bound.
Data on Table 3 below suggests that differences do exist in diagnosis of eye
conditions across different age groups, but that there is no pronounced differ-
ence in diagnosis of eye conditions within each age group category.
Median 1.000
Variance 0.249
Median 1.000
Variance 0.249
Median 1.000
Variance 0.250
Year of Diagnosis
population sample presented with eye problems in 2018 while only 33% did the
same in 2019 and only 10.9% of the study population presented with eye prob-
lems in 2020.
4. Discussion
This study presented a cursory analysis into the frequency and patterns of com-
mon childhood eye conditions presenting in two major referral eye hospitals in a
low-resourced setting. Hospital based data was used to show trends and patterns
of eye conditions as reflected on the study sample and this data adds confidence
in the results obtained because diagnoses were conducted by qualified eye health
experts as opposed to having to elicit views from respondents which may have
social desirability or recall biases. It must be noted at this point that there are few
studies in Zimbabwe which have attempted to characterize the burden of eye
conditions among children and that this study adds to the growing body of evi-
dence on this important public health problem. Additionally, this study is im-
portant as it included the two major referral centres in Zimbabwe which are lo-
cated at vantage sites, which geographically covers the whole country.
Results showed that more records were extracted and analysed from Harare,
which can be attributed to the fact that the northern provinces of Zimbabwe are
more populated than the southern regions. It may also be related to the percep-
tion that a lot more Zimbabweans may be inclined to seek services in Harare as
it is perceived to have better services by virtue of it being the capital city. It is
also important to note that Richard Morris Hospital refers some conditions to
Sekuru Kaguvi, for instance, those requiring paediatric oncology services. Inter-
estingly, results showed no differences on the types of eye diseases seen in the
two hospital centres. Therefore, there were no geographical variations for most
of the conditions that were reviewed.
By comparison, 469 Ophthalmia neonatorum cases were reported at Richard
Morris whereas SKH only reported 3 cases. Ophthalmia neonatorum is a notifi-
able condition and treatment should be done at the local health centres. This
might mean that the Northern region is managing the condition locally and the
Southern region health centres were referring to Richard Morris. A standardised
protocol of treatment should therefore be followed. Such discrepancies need to
be explored in future research so that uniformity is maintained and that deserv-
differences could be due to the effects of the COVID-19 pandemic which sig-
nificantly altered access to health care services because schools closed and lock-
downs restricted movement for many people, and thus may have hindered chil-
dren from accessing eye screening and diagnosis services.
5. Study Limitations
The major limitation of the study was that it was conducted during the time of
COVID-19 pandemic and thus could only be a retrospective review. Richer in-
formation could have been obtained from face-to-face interviews with caregiv-
ers. Moreover, the study was retrospective in nature and utilised data from pa-
tient registers from the hospitals. Reporting tools from the two hospitals were
different rendering it difficult for some variables to be compared. In addition,
some records at the hospitals were incomplete or missing data and this made
data extraction and review difficult.
The study was hospital based and as such results cannot be generalized to the
rest of the population outside this setting. The study did not conduct interviews
or have any physical contact with participants. This limitation means that there
might be some vital information that might have been missed from the caregiv-
ers and the patients. In addition, it was also noted that the two paediatric hospit-
als used slightly different data capturing tools which compromised merging of
the datasets in some instances and therefore, some data may have been lost.
Childhood blindness could not be calculated due to different data sets as one eye
unit did not record the visual acuity for patients in the years that were under
study.
6. Conclusions
The study sought to:
1) Determine the patterns of childhood blindness and severe visual impair-
ment in children below the age of 15 years.
2) Identify the major eye conditions that children who attend the Harare and
Bulawayo paediatric hospitals present with.
3) Identify patterns of the eye conditions that children who visit the Harare
and Bulawayo Eye Units present with.
Results of the study underscore the urgent need to prioritize eye health for
children in Zimbabwe and to institute interventions which would help reduce
this growing burden presented by eye diseases. With regards to the pattern of the
conditions, the study findings revealed that children are affected in different
ways. Some have both eyes affected whilst others have either one eye affected by
these different conditions. The challenge of managing childhood eye injuries is
enormous with considerations ranging from late presentation to eye care centres
and lack of facilities, the low socioeconomic status of the children involved, the
special care required during examination, postoperative management and the
risk of secondary vision loss. Prevention of ocular trauma in children remains a
priority in order to reduce ocular morbidity. This will involve the adequate edu-
cation of children, parents and teachers to ensure adequate supervision during
playtime.
7. Recommendations
1) The paediatric hospitals should have similar data capturing tools so as to
ensure ease of merging data for programming purposes. In view of this more in-
vestment in data recording and storage should be encouraged especially using
electronic database systems which are able to show real-time trends.
2) Integration of eye screening at Post Natal Units and Child Immunization
Programmes is essential for early identification and treatment of the conditions
that are found in the 0 to 5 age group.
3) Effective screening should be conducted especially at community level with
the involvement of community health workers. This could also involve scaling
up prevention, health education and early presentation of children to ophthal-
mic hospitals for treatment of eye disorders are also essential.
4) General nurses and community health workers should be given basic pri-
mary eye care training so as to reduce the number of conditions referred to
the tertiary institution as some of these can be treated at the health centre (oph-
thalmia neonatorum).
5) More resources should be channeled towards the prevention and cure of
allergic conjunctivitis, eye injuries and lid pathology especially in younger age
groups which appear to more affected.
Acknowledgements
Council for the Blind Zimbabwe and the Ministry of Health and Child Care
would like to thank CBM International, the Lions Club International Founda-
tion; Lions Deutschland and Wir Helfen Kinden for funding this study.
Conflicts of Interest
The authors declare no conflicts of interest regarding the publication of this pa-
per.
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