S.P.

Mandal’s
KANKAVLI COLLEGE, KANKAVLI
(Affiliated to University of Mumbai)
SYLLABUS AND PROGRAMMME / COURSE OUTCOMES
DEPARTMENT OF CHEMISTRY

SR. COURSE PAPER

NAME OF THE PAPER
NO CODE NUMBER
1 USCH101 General Chemistry I
2 USCH102 General Chemistry II
3 USCHP1 Chemistry Practical --
4 USCH201 General Chemistry I
5 USCH202 General Chemistry II
6 USCHP2 Chemistry Practical --
7 USCH301 General Chemistry I
8 USCH302 General Chemistry II
9 USCH303 Analytical Chemistry III
10 USCHP1 Chemistry Practicals I --
11 USCHP2 Chemistry Practicals II --
12 USCHP3 Chemistry Practicals III --
13 USCH401 General Chemistry I
14 USCH402 General Chemistry II
15 UDCH403 Analytical Chemistry III
16 USCHP4 Chemistry Practicals I --
17 USCHP5 Chemistry Practicals II --
18 USCHP6 Chemistry Practicals III --
11 USCH501 Physical Chemistry I
12 USCH502 Inorganic Chemistry II
13 USCH503 Organic Chemistry III
14 USCH504 Analytical Chemistry IV
15 USACDD501 Drugs & Dyes --
16 USCHP01 Physical Chemistry Practicals --
17 USCHP05 Inorganic Chemistry Practicals --
18 USCHP09 Organic Chemistry Practical --

DEPARTMENT OF CHEMISTRY
 19 USCHP13 Analytical Chemistry Practical --
20 USACDD5P1 Drugs & Dyes Practical --
21 USCH601 Physical Chemistry I
22 USCH602 Inorganic Chemistry II
23 USCH603 Organic Chemistry III
24 USCH604 Analytical Chemistry IV
25 USACDD601 Drugs & Dyes --
26 USCHP02 Physical Chemistry Practical --
27 USCHP06 Inorganic Chemistry Practical --
28 USCHP10 Organic Chemistry Practical --
29 USCHP14 Analytical Chemistry Practical --
30 USACDD6P1 Drugs & Dyes Practical --

S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Programmme: B. Sc. Course: Chemistry

Programmme Outcomes:
PO1 The students after completion of B.Sc. programme in Chemistry will develop the clear understanding
of theoretical chemistry concepts and an analytical approach.
PO2 Students will be able to develop critical thinking ability by way of solving problems.
PO3 Students will become capable of expressing the subject through writing skills as well as through oral
presentation.
PO4 The students will develop a spirit of inquiry, develop new skills and enhance scientific knowledge
through experimental learning.
PO5 The students will able to inculcate habit of learning continuously (lifelong learner) for personal
academic growth as well as for increasing employability opportunity.
PO6 Student will have an ability to develop social interactions, ethical awareness/reasoning and all round
personality.

Programme Specific Outcomes :

PSO1 Student will gain sound understanding of fundamental concepts in Organic, Inorganic, Physical and
Analytical chemistry.
PSO2 Students will be able to understand the basic principle of equipments, instruments used in the

DEPARTMENT OF CHEMISTRY
 chemistry laboratory.
PSO3 Students will get an idea about designing & performing the experiments, recoding and analyzing
the data in scientific manner.
PSO4 Students will learn the handling of sophisticated instruments like pH meter, conductometer etc.
PSO5 Students will gain knowledge of mechanism of chemical reactions and characterization of any
substance.
PSO6 Students will develop skill of handling chemicals safely and good laboratory practices.
PSO7 Students will able to perform different processes and unit operations used in industries.
PSO8 Students will aware about the applications of chemistry in day-to-day life and in the improvement
of standard of living of human being.
PSO9 Students will be able to find new areas of research in both chemistry and allied fields of science and
technology.
PSO10 Students will gain awareness about environment and thus helps in sustainable development.
PSO11Students will learn how to work as a team and thus follow professional ethics.
PSO12 Students will gain knowledge & skills to take higher studies in chemistry & allied sciences that
can helpful for self-employment/entrepreneurship.

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry Paper I
Program Code: 1S00141 Course Code: USCH101
(As per the Credit Based Semester and Grading System with effect from the academic year 2016-17)

Class: F. Y. B. Sc. Semester : I

Course Outcomes:
Upon completion of this course the learner will be able to:
CO1 Understand the basic thermodynamic terms, properties, functions, laws and about thermochemistry.
CO2 Learn various terms used to express concentration of solution and their interconversion.
CO3 Get information about historical perspective in the development of atomic structure.
CO4 Know about periodic table, periodicity of various elements and their properties.
CO5 Write the IUPAC names of organic compounds from their structure and vice versa.
CO6 Predict hybridization of atoms in organic compounds, shape of organic molecules and information
about their nature of bonding.
CO7 Explain the fundamental concepts of organic reaction mechanism and identify the type of organic
reaction.

DEPARTMENT OF CHEMISTRY
Unit I: Chemical Thermodynamics: (10L)
Thermodynamic terms: System, surrounding, boundaries, open, closed and isolated system, intensive and
extensive properties, state functions and path functions, zeroth law of thermodynamics. First law of
thermodynamics: concept of heat (q), work (w), internal energy (U), statement of first law, enthalpy,
relation between heat capacities, sign conventions, calculations of heat (q), work (w), internal energy (U),
and enthalpy (H) (Numericals expected) Thermochemistry: Heats of reactions, standard states, enthalpy of
formation of molecules, enthalpy of combustion and its applications, calculation of bond energy, bond
dissociation energy and resonance energy from thermochemical data, Kirchhoff’s equation (Numericals
expected)
Chemical Calculations: (5L)
Expressing concentration of solutions: Normality, molality, molarity, formality, mole fractions, weight
ratio, volume ratio, weight to volume ratio, ppm, ppb, millimoles, milliequivalents (Numericals expected).
Unit II: 2.1 Atomic structure: (10L)
a) Historical perspectives of the atomic structure; Rutherford’s Atomic Model, Bohr’s theory, its
limitations and atomic spectrum of hydrogen atom. Structure of hydrogen atom.
b) Hydrogenic atoms: 1. Simple principles of quantum mechanics; 2. Atomic orbitals i) Hydrogenic
energy levels ii) Shells, subshells and orbitals iii) Electron spin iv) Radial shapes of orbitals v) Radial
distribution function vi) Angular shapes of orbitals 3. Many Electron Atoms: i) Penetration and shielding
ii) Effective nuclear charge 4. Aufbau principle.
Periodic Table and periodicity : (5L)
Long form of Periodic Table; Classification for elements as main group, transition and inner transition
elements; Periodicity in the following properties: Atomic and ionic size; electron gain enthalpy; ionization
enthalpy, effective nuclear charge (Slater’s rule); electronegativity; Pauling, Mulliken and Alred Rochow
electronegativities (Numerical problems expected, wherever applicable.)
Unit III: Basics of Organic Chemistry
3.1 Classification and Nomenclature of Organic Compounds: (5L)
Review of basic rules of IUPAC nomenclature. Nomenclature of mono and bi-functional aliphatic
compounds on the basis of priority order of the following classes of compounds: alkanes, alkenes,
alkynes, haloalkanes, alcohols, ethers, aldehydes, ketones, carboxylic acids, carboxylic acid derivatives
(acid halides, esters, anhydrides, amides), nitro compounds, nitriles and amines; including their cyclic

DEPARTMENT OF CHEMISTRY
analogues.
3.2 Bonding and Structure of organic compounds: (4L)
Hybridization: sp3, sp2, sp hybridization of carbon and nitrogen; sp3 and sp2 hybridizations of oxygen in
Organic compounds (alcohol, ether, aldehyde, ketone, carboxylic acid, ester, cyanide, amine and amide)
Overlap of atomic orbitals: Overlaps of atomic orbitals to form sigma and pi bonds, shapes of organic
molecules. Shapes of molecules; Influence of hybridization on bond properties (as applicable to ethane,
ethene, ethyne)
3.3 Fundamentals of organic reaction mechanism: (6L)
Electronic Effects: Inductive, electromeric, resonance and mesomeric effects, hyperconjugation and their
applications; Dipole moment; Organic acids and bases; their relative strengths. Bond fission: Homolytic
and Heterolytic fission with suitable examples. Electrophiles and Nucleophiles; Nucleophilicity and
basicity; Types (primary, secondary, tertiary, allyl, benzyl), shape and their relative stability of reactive
intermediates: Carbocations, Carbanions and Free radicals. Introduction to types of organic reactions:
Addition, Elimination and Substitution reaction. (With one example of each).

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry Paper II
Program Code: 1S00141 Course Code: USCH102
(As per the Credit Based Semester and Grading System with effect from the academic year 2016-17)

Year: F. Y. B. Sc. Semester : I

Course Outcomes:
Upon completion of this course the learner will be able to:
CO1 Understand the factors affecting on rate of reaction & able to calculate the order of reactions.
CO2 Know about properties of liquids and its applications.
CO3 Identify and describe the different types of liquid crystals.
CO4 Learn and explain physical and chemical properties of main group elements and their compounds.
CO5 Know about sources of air pollutants, effect of air pollution and precautionary measures.
CO6 Aware about stereochemical terms, difference between conformation & configuration, and
conformational analysis.

Unit – I:
1.1 Chemical Kinetics: (8L)
Rate of reaction, rate constant, measurement of reaction rates, order and molecularity of reaction,
integrated rate equation of first and second order reactions (with equal initial concentration of reactants)
(Numericals expected) Determination of order of reaction by (a) Integration method (b) Graphical method
(c) Ostwald’s isolation method (d) Half time method (Numericals expected).
1.2 Liquid State: (7L)
Surface tension: Introduction, methods of determination of surface tension by drop number method
(Numericals expected) Viscosity: Introduction, coefficient of viscosity, relative viscosity, specific
viscosity, reduced viscosity, determination of viscosity by Ostwald viscometer (Numericals
expected)Refractive index: Introduction, molar refraction and polarizability, determination of refractive
index by Abbe’s refractometer (Numericals expected)Liquid crystals: Introduction, classification and

DEPARTMENT OF CHEMISTRY
structure of thermotropic phases (Nematic, smectic and cholesteric phases), applications of liquid crystals
Unit – II:
Comparative chemistry of Main Group Elements: (15L)
Metallic and non-metallic nature, oxidation states, electronegativity, anomalous behaviour of second period
elements, allotropy, catenation, diagonal relationship. Comparative chemistry of carbides, nitrides, oxides and
hydroxides of group I and group II elements. Some important compounds- NaHCO3, Na2CO3, NaCl, NaOH, CaO,
CaCO3; oxides of carbon, oxides and oxyacids of sulphur and nitrogen with respect to environmental aspects.
Unit – III:
Stereochemistry I: (15L)
Fischer Projection, Newman and Sawhorse Projection formulae (of erythro, threo isomers of tartaric acid
and 2,3-dichlorobutane) and their interconversions ; Geometrical isomerism in alkene and cycloalkanes:
cis–trans and syn-anti isomerism E/Z notations with C.I.P rules. Optical Isomerism: Optical Activity,
Specific Rotation, Chirality/Asymmetry, Enantiomers, Molecules with two similar and dissimilar chiral-
centres, Distereoisomers, meso structures, racemic mixture and resolution (methods of resolution not
expected). Relative and absolute configuration: D/L and R/S designations. Conformation analysis of
alkanes (ethane, propane and n-butane); Relative stability with energy diagrams.
References-
Unit I
1. Atkins P.W. and Paula J.de, Atkin’s Physical Chemistry, 10th Ed., Oxford University 12 Press (2014).
2. Ball D.W., Physical Chemistry, Thomson Press, India (2007).
3. Castellan G.W., Physical Chemistry, 4th Ed., Narosa (2004).
4. Mortimer R.G., Physical Chemistry, 3rd Ed., Elsevier: NOIDA, UP (2009).
5. Engel T. and Reid P., Physical Chemistry, 3rd Ed., Pearson (2013).
6. Peter A. and Paula J. de. Physical Chemistry, 10th Ed., Oxford University Press (2014).
7. McQuarrie D.A. and Simon J.D., Molecular Thermodynamics, Viva Books Pvt. Ltd.New Delhi (2004).
8. Levine I.N., Physical Chemistry, 6th Ed., Tata Mc Graw Hill (2010).
9. Metz C.R., 2000 Solved Problems in Chemistry, Schaum Series (2006).
10. Mortimer R.G., Physical Chemistry, 3rd Ed., Elsevier: NOIDA, UP (2009).
11. Banwell C.N., Fundamentals of Molecular Spectroscopy, 4th Ed., Tata McGraw Hill (1994).
12. K.L. Kapoor, A Textbook of Physical Chemistry, Macmillan (2000)
Unit II

DEPARTMENT OF CHEMISTRY
1. Lee, J.D. Concise Inorganic Chemistry ELBS, 1991.
2. Douglas, B.E. and McDaniel, D.H. Concepts & Models of Inorganic Chemistry Oxford, 1970
3. Atkins, P.W. & Paula, J. Physical Chemistry, 10th Ed., Oxford University Press, 2014.
4. Day, M.C. and Selbin, J. Theoretical Inorganic Chemistry, ACS Publications, 1962.
5. Rodger, G.E. Inorganic and Solid State Chemistry, Cengage Learning India Edition, 2002
Unit III
1. Morrison, R. T. and Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt Ltd. (Pearson
Education).2012
2. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt Ltd. (Pearson Education).
3. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural Products),
Dorling Kindersley (India) Pvt Ltd. (Pearson Education).
4. Eliel, E. L. and Wilen, S. H. Stereochemistry of Organic Compounds, Wiley: London, 1994.
5. Kalsi, P. S. Stereochemistry Conformation and Mechanism, New Age International, 2005.
6. Mc Murry, J.E. Fundamentals of Organic Chemistry, 7th Ed. Cengage Learning India Edition, 2013

DEPARTMENT OF CHEMISTRY
Semester End Theory Examinations: Question Paper Pattern

There will be a Semester-end external theory examination of 100 marks for each of the courses
USCH101 and USCH102 of Semester I to be conducted by College.

Duration: The examinations shall be of 3 Hours duration.

1. Theory Question Paper Pattern:

a) There shall be FIVE questions. The Q.1 shall be of objective type for 20 marks based on the
entire syllabus consisting of multiple choice questions, match the following, true or false etc. The
questions Q.2, Q.3 and Q.4 shall be of 20 marks, each based on the unit I (Physical Chemistry),
unit II (Inorganic Chemistry) and Unit III (Organic Chemistry) respectively. Q.5 is based on all
the three units.

b) All the questions are compulsory. The questions Q.2, Q.3, Q.4, Q. 5 shall have internal
choices within the questions. Including the choices, the marks for each question shall be of 30.

c) The questions Q.1, Q.2, Q.3, Q.4 and Q.5 may be subdivided into sub-questions as A, B, C, D,
E & F.

Q.1 Based On Unit I, II & III

(A) Select the correct option and complete the following sentences. (Any twelve) 12

(B) State whether the following statements are true or false. (Any three) 03
(C) Match the column. (Any five) 05

Q. 2 Attempt any four from A/B/C/D/E/F Unit I Marks 20

Q. 3 Attempt any four from A/B/C/D/E/F Unit II Marks 20
Q. 4 Attempt any four from A/B/C/D/E/F Unit III Marks 20
Q. 5 Attempt any four from A/B/C/D/E/F Unit I, II & III Marks 20

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Chemistry Practical Based on Paper I & II
Program Code: 1S00141 Course Code: USCHP1
(As per the Credit Based Semester and Grading System with effect from the academic year 2016-17)

Class: F. Y. B. Sc. Semester : I

Course Outcomes:
Upon completion of this course the learner will be able to:
CO1 Learn concept of primary and secondary standards and the methods to standardise solutions.
CO2 Know role of indicators, choice of indicators and how to design double indicator titration
CO3 Explain the difference between order and molecularity of reaction.
CO4 Understand the importance of rate constant of the reaction.
CO5 Learn the quantitative determination by weight.
CO6 Aware about importance of purity and learn the techniques of purification.
CO7 Acquainted with the organic mixture separation techniques.

Chemistry Practical Paper I

1. To prepare 0.1 N succinic acid and standardize the NaOH of two different concentrations.
2. To determine the rate constant for the hydrolysis of ester using HCl as catalyst.
3. To determine enthalpy of dissolution of salt (like KNO3)
4. Commercial analysis of (any two)
a) Mineral acid
b) Organic acid
c) Salt of weak acid and strong base.
5. Titration using double indicator: analysis of solution of Na2CO3 and NaHCO3.
Chemistry Practical Paper II
1. Gravimetric analysis
a) To determine the percent purity of sample of BaSO4 containing NH4Cl.
b) To determine the percent purity of ZnO containing ZnCO3.

DEPARTMENT OF CHEMISTRY
2. Purification of any two organic compounds by recrystallization selecting suitable solvent.
Learners are expected to report a) Solvent for recrystallization. b) Mass and the melting points of purified
compound.
3. Chromatography (Any one)
a) Separation of a mixture of two sugars by ascending paper chromatography.
b) Separation of a mixture of o-and p-nitrophenols by thin layer chromatography (TLC).

: Question Paper Pattern :

Each Chemistry Practical Paper is of 50 Marks and 3 hours duration.

Maximum Marks: 50 Marks
Time: 3 Hours
Note: 1) Attempt all Questions
1. Perform given experiment and tabulate the result as per guidelines. 40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
Detailed scheme of marking of Experiment.

Observation 26
Reaction 02
Calculation 08
Systematic work 04
Total 40

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry Paper I
Program Code: 1S00142 Course Code: USCH201
(As per the Credit Based Semester and Grading System with effect from the academic year 2016-17)

Class: F. Y. B. Sc. Semester : II

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Understand the effect of pressure, temperature and amount on volume of gas with the help of gas
laws.
CO2 Know about various conditions to establish chemical equilibria
CO3 State the Second law and understand the significance of free energy.
CO4 Learn to perform qualitative analysis of gaseous evolutes.
CO5 Learn various acid –base concepts, volumetric analysis of acid & base by drawing titration curves
CO6 Know the application of acids in various organic reactions.
CO7 Know about the preparation of alkanes, alkenes and alkynes by using various methods.
CO8 Learn preparation of various other organic compounds from alkanes, alkenes and alkynes.

Unit – I
1.1 Gaseous State: (8L)
Ideal gas laws, kinetic theory of gases, Maxwell-Boltzmann’s distribution of velocities (qualitative
discussion), ideal gases, real gases, compressibility factor, Boyle’s temperature (Numericals expected)
Deviation from ideal gas laws, reasons for deviation from ideal gas laws, Van der Waals equation of state,
Joule-Thomson effect: qualitative discussion and experimentation, inversion temperature. (Numericals
expected)
1.2 Chemical Equilibria and Thermodynamic Parameters: (7L)
Reversible and irreversible reactions, law of mass action, dynamic equilibria, equilibrium constant, (Kc
and Kp), relationship between Kc and Kp, Le Chatelier's principle, factors affecting chemical equilibrium
(Numericals expected) Statement of second law of thermodynamics, concepts of entropy and free energy,

DEPARTMENT OF CHEMISTRY
spontaneity and physical significance of free energy, thermodynamic derivation of equilibrium constant
(Numericals expected).
Unit II
2.1 Concept of Qualitative Analysis: (7L)
a) Testing of Gaseous Evolutes, Role of Papers impregnated with Reagents in qualitative analysis (with
reference to papers impregnated with starch iodide, potassium dichromate, lead acetate, dimethyl
glyoxime and oxine reagents).
b) Precipitation equilibria, effect of common ions, uncommon ions, oxidation states, buffer action,
complexing agents on precipitation of ionic compounds. (Balanced chemical equations and numerical
problems expected.)
2.2 Acid Base Theories: (8L)
Arrhenius, Lowry- Bronsted, Lewis, Solvent – Solute concept of acids and bases, Hard and Soft acids and
bases. Applications of HSAB Applications of acid base chemistry in: i) Understanding organic reactions
like Friedel Craft’s (acylation/alkylation) reaction ii) Volumetric analysis with special reference to
calculation of titration curve involving strong acid and strong base.
Unit III
3. Chemistry of Aliphatic Hydrocarbons
3.1 Carbon-Carbon sigma bonds: (3L)
Chemistry of alkanes: Formation of alkanes, Wurtz Reaction, Wurtz-Fittig Reactions, Free radical
substitutions: Halogenation -relative reactivity and selectivity.
3.2 Carbon-Carbon pi bonds: (12L)
Formation of alkenes and alkynes by elimination reactions: Mechanism of E1, E2, E1cb reactions. Saytzeff
and Hofmann eliminations. Reactions of alkenes: Electrophilic additions their mechanisms
(Markownikoff/ Anti Markownikoff addition), Mechanism of oxymercuration-demercuration,
hydroboration-oxidation, ozonolysis, reduction (catalytic and chemical), syn and anti-hydroxylation
(oxidation). 1, 2-and 1, 4-addition reactions in conjugated dienes and, Diels-Alder reaction; Allylic and
benzylic bromination using N-bromosuccinimide and mechanism, e.g. propene, 1-butene, toluene,
ethylbenzene.
Reactions of alkynes: Acidity, Electrophilic and Nucleophilic additions. Hydration to form carbonyl
compounds, Alkylation of terminal alkynes.

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry Paper II
Program Code: 1S00142 Course Code: USCH202
(As per the Credit Based Semester and Grading System with effect from the academic year 2016-17)

Class: F. Y. B. Sc. Semester : II

Course Outcomes:
Upon completion of this course the students will be able to:
C01 State the types of electrolytes and their ionizational behaviour.
C02 Explain types of buffer and their action.
CO3 Learn the interaction of electromagnetic radiation with matter.
CO4 Understood the various arrangements of atoms with in space in a crystalline solids.
CO5 Learn about nature of chemical bonding and reactivity during the formation of inorganic compounds
with the help of various theories.
CO6 Know the application of redox chemistry in extraction of elements and redox reagents in volumetric
analysis.
CO7 Distinguish organic compounds as aromatic, anti-aromatic and non-aromatic.
CO8 Write the mechanism of various aromatic electrophilic reactions.
CO9 Learn about conformations and stability of cyclic alkanes.

Unit- I:
1.1 Ionic Equilibria: (7L)
Strong, moderate and weak electrolytes, degree of ionization, factors affecting degree of ionization,
ionization constant and ionic product of water, ionization of weak acids and bases, pH scale, common ion
effect, dissociation constants of mono-, di- and triprotic acid (exact treatment for monoprotic acid)
Buffers: Introduction, types of buffers, derivation of Henderson equation for acidic and basic buffers,
buffer action, buffer capacity (Numericals expected).
1.2 Molecular Spectroscopy: (4L)

DEPARTMENT OF CHEMISTRY
Electromagnetic radiation, electromagnetic spectrum, Planck’s equation, interaction of electromagnetic
radiation with matter: Absorption, emission, scattering, flourescence, electronic, vibrational and rotational
transitions, Beer-Lambert’s law (Numericals expected).
1.3 Solid State Chemistry (4L)
Types of solids, crystal lattice, lattice points, unit cell, space lattice and lattice plane, laws of
crystallography: Law of constancy of interfacial angle, law of symmetry and law of rational indices
(Numericals expected).
Unit -II:
2.1: Chemical Bond and Reactivity: (7L)
Types of chemical bond, comparison between ionic and covalent bonds, polarizability (Fajan’s Rule),
shapes of molecules, Lewis dot structure, Sidgwick Powell Theory, basic VSEPR theory for ABn type
molecules with and without lone pair of electrons, isoelectronic principles, applications and limitations of
VSEPR theory.
2.2: Oxidation Reduction Chemistry: (8L)
a) Reduction potentials b) Redox potentials: half reactions; balancing redox equations. c) Redox stability
in water i) Latimer and Frost Diagrams ii) pH dependence of redox potentials. d) Applications of redox
chemistry i) Extraction of elements: (example: isolation of copper by auto reduction) ii) Redox reagents in
Volumetric analysis: a) I2; b) KMnO4 iii) Titration curves: i) single electron systems (example Ce (IV)
against Fe (II)); and ii) Multi electron systems as in KMnO4 against Fe (II).
Unit III:
3.1 Stereochemistry-II: Cycloalkanes and Conformational Analysis: (5L)
Types of cycloalkanes and their relative stability, Baeyer strain theory, Conformation analysis of
cyclohexane: Chair, Boat and Twist boat forms; Relative stability with energy.
3.2 Aromatic Hydrocarbons: (10L)
Aromaticity: Hückel’s rule anti-aromaticity, aromatic character of arenes, cyclic carbocations/carbanions
and heterocyclic compounds with suitable examples. Electrophilic aromatic substitution: halogenation,
nitration, sulphonation and Friedel-Craft alkylation/acylation with their mechanism. , Hammond’s
postulate, Directing effects of the groups.
Reference Books:
Unit I
1. Atkins P.W. and Paula J.de, Atkin’s Physical Chemistry, 10th Ed., Oxford University 12 Press (2014).

DEPARTMENT OF CHEMISTRY
2. Ball D.W., Physical Chemistry, Thomson Press, India (2007).
3. Castellan G.W., Physical Chemistry, 4th Ed., Narosa (2004).
4. Mortimer R.G., Physical Chemistry, 3rd Ed., Elsevier: NOIDA, UP (2009).
5. Engel T. and Reid P., Physical Chemistry, 3rd Ed., Pearson (2013).
6. Peter A. and Paula J. de. Physical Chemistry, 10th Ed., Oxford University Press (2014).
7. McQuarrie D.A. and Simon J.D., Molecular Thermodynamics, Viva Books Pvt. Ltd., New Delhi 2004).
8. Levine I.N., Physical Chemistry, 6th Ed., Tata Mc Graw Hill (2010).
9. Metz C.R., 2000 Solved Problems in Chemistry, Schaum Series (2006).
10. Mortimer R.G., Physical Chemistry, 3rd Ed., Elsevier: NOIDA, UP (2009).
11. Banwell C.N., Fundamentals of Molecular Spectroscopy, 4th Ed., Tata McGraw Hill (1994).
12. K.L. Kapoor, A Textbook of Physical Chemistry, Macmillan (2000).
Unit II
1. Lee, J.D. Concise Inorganic Chemistry ELBS, 1991.
2. Douglas, B.E. and McDaniel, D.H. Concepts & Models of Inorganic Chemistry Oxford, 1970
3. Atkins, P.W. & Paula, J. Physical Chemistry, 10th Ed., Oxford University Press, 2014.
4. Day, M.C. and Selbin, J. Theoretical Inorganic Chemistry, ACS Publications, 1962.
5. Rodger, G.E. Inorganic and Solid State Chemistry, Cengage Learning India Edition, 2002
Unit III
1. Morrison, R. T. and Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt Ltd. (Pearson
Education).2012
2. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt Ltd. (Pearson Education).
3. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural Products),
Dorling Kindersley (India) Pvt Ltd. (Pearson Education).
4. Eliel, E. L. and Wilen, S. H. Stereochemistry of Organic Compounds, Wiley: London, 1994.
5. Kalsi, P. S. Stereochemistry Conformation and Mechanism, New Age International, 2005.
6. Mc Murry, J.E. Fundamentals of Organic Chemistry, 7th Ed. Cengage Learning India Edition, 2013

DEPARTMENT OF CHEMISTRY
Semester End Theory Examinations:
There will be a Semester-end external theory examination of 100 marks for each of the courses USCH201
and USCH202 of Semester II to be conducted by College.
Duration: The examinations shall be of 3 Hours duration.
Theory Question Paper Pattern:
a) There shall be FIVE questions. The Q.1 shall be of objective type for 20 marks based on the entire
syllabus consisting of multiple choice questions, match the following, true or false etc. The questions Q.2,
Q.3 and Q.4 shall be of 20 marks, each based on the unit I (Physical Chemistry), unit II (Inorganic
Chemistry) and Unit III (Organic Chemistry) respectively. Q.5 is based on all the three units.
b) All the questions are compulsory. The questions Q.2, Q.3, Q.4, Q. 5 shall have internal choices within
the questions. Including the choices, the marks for each question shall be of 30.
c) The questions Q.1, Q.2, Q.3, Q.4 and Q.5 may be subdivided into sub-questions as A, B, C, D, E & F.
Q.1 Based On Unit I, II & III
(A) Select the correct option and complete the following sentences. (any twelve) 12
(B) State whether the following statements are true or false. (any three) 03
(C) Match the column. (any five) 05
Q. 2 Attempt any four from A/B/C/D/E/F Unit I Marks 20
Q. 3 Attempt any four from A/B/C/D/E/F Unit II Marks 20
Q. 4 Attempt any four from A/B/C/D/E/F Unit III Marks 20
Q. 5 Attempt any four from A/B/C/D/E/F Unit I, II & III Marks 20

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Chemistry Practical Based on Paper I & II
Program Code: 1S00142 Course Code: USCHP2
(As per the Credit Based Semester and Grading System with effect from the academic year 2016-17)

Class: F. Y. B. Sc. Semester : II

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Know how to use instruments like pH meter for determination of dissociation constant of Weak
Acid.
CO2 Use Colorimeter instrument for determination of KMnO4 concentration in given solution by
verifying Beer-Lambert’s law.
CO3 Compute rate constant of base catalysed ester hydrolysis.
CO4 Know about safety precautions to be taken during handling chemicals by writing MSDS.
CO5 Learn to identify the cations and anions present in unknown mixture by semi-micro inorganic
qualitative analysis.
CO6 Study redox type titration in determination of percentage of copper (II) in given sample.
CO7 Identify the possible name and structure of unknown organic compound by performing systematic
qualitative analysis of organic compound through detection of elements (C, H, (O), N, S, X) and
functional group.

Unit I: Physical Chemistry

1. To determine the rate constant for the saponification reaction between ethyl acetate and NaOH.
2. To determine dissociation constant of weak acid (Ka) using Henderson’s equation and the method of
incomplete titration pH metrically.
3. To verify Beer-Lambert’s law, using KMnO4 solution by colorimetric method.
4. To standardize commercial sample of HCl using borax and to write material safety data of the
chemicals involved.

DEPARTMENT OF CHEMISTRY
Unit II: Inorganic Chemistry
1. Qualitative analysis: (at least 4 mixtures to be analyzed)
Semi-micro inorganic qualitative analysis of a sample containing two cations and two anions.
Cations (from amongst): Pb2+, Ba2+, Ca2+, Sr2+, Cu2+, Cd2+, Fe2+, Ni2+, Mn2+, Mg2+, Al3+, Cr3+, K+, NH4+
Anions ( From amongst): CO32-, S2-, SO32-, NO2-, NO3-, Cl-, Br-, I-, SO42-, PO43-
(Scheme of analysis should avoid use of sulphide ion in any form for precipitation / separation of cations.)
2. Redox Titration: To determine the percentage of copper (II) present in a given sample by titration
against a standard aqueous solution of sodium thiosulfate (iodometry titration).
Unit III: Organic Chemistry
Characterization of organic compound containing C, H, (O), N, S, X elements. (minimum 6 compounds)
References:
Unit I: Physical Chemistry
1. Khosla B.D., Garg V.C. and Gulati A., Senior Practical Physical Chemistry, R. Chand and Co., New
Delhi (2011).
2. Garland C. W., Nibler J.W. and Shoemaker D.P., Experiments in Physical Chemistry, 8th Ed.,
McGraw-Hill, New York (2003).
3. Halpern A.M. and McBane G.C., Experimental Physical Chemistry, 3rd Ed., W.H. Freeman and Co.,
New York (2003).
4. Athawale V.D. and Mathur P., Experimental Physical Chemistry, New Age International, New Delhi
(2001).
Unit II: Inorganic Chemistry
Mendham, J., A. I. Vogel’s Quantitative Chemical Analysis 6th Ed., Pearson, 2009
Unit III: Organic Chemistry
1. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)
2. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed.,
Pearson (2012)
3. Vogel, A.I., Tatchell, A.R., Furnis, B.S., Hannaford, A.J. & Smith, P.W.G. Textbook of Practical
Organic Chemistry, Prentice-Hall, 5th edition, 1996

DEPARTMENT OF CHEMISTRY
 : Question Paper Pattern :

Each Chemistry Practical Paper is of 50 Marks and 3 hours duration.

Maximum Marks: 50 Marks
Time: 3 Hours
Note: 1) Attempt all Questions
1. Perform given experiment and tabulate the result as per guidelines. 40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
Detailed scheme of marking of Experiment.

Observation 26
Reaction 02
Calculation 08
Systematic work 04
Total 40

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry I
Program Code: 1S00143 Course Code: USCH301
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-2018)
Class: S. Y. B. Sc. Semester : III

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Derive equations for free energy functions
CO2 Perform numerical calculations in thermodynamics.
CO3 Understand the types of conductivities and its variation with dilution.
CO4 Apply Kohlrausch’s law for the determination of degree of dissociation of weak electrolytes.
CO5 Learn the non-directional bonding in ionic crystal.
CO6 Know the formation of covalent bonds through orbital approach, types of hybridizations with
examples.
CO7 Calculate bond order and magnetic property in O2 species by using Molecular Orbital Theory.
CO8 Illustrate reactions & reactivity of halogenated hydrocarbon
CO9 Understand the methods of preparation and reactions of alcohols, epoxides and phenols.
CO10 Know the use of Organomagnesium and Organolithium compounds in synthesis of other
compounds.

Unit I:Physical Chemistry

1.1 Chemical Thermodynamics-II (8L)
1.1.1 Free Energy Functions: Helmholtz Free Energy, Gibb's Free Energy, Variation of Gibb's free energy
with Pressure and Temperature.
1.1.2 Gibbs-Helmholtz equation, van't Hoff reaction isotherm and van't Hoff reaction isochore.
(Numericals expected).
1.1.3 Thermodynamics of Open System: Partial Molal Properties, Chemical Potential and its variation
with Pressure and Temperature, Gibb's Duhem equation.
1.1.4 Concept of Fugacity and Activity

DEPARTMENT OF CHEMISTRY
1.2 Electrochemistry: (7L)
1.2.1 Conductivity, equivalent and molar conductivity and their variation with dilution for weak and
strong electrolytes.
1.2.2 Kohlrausch law of independent migration of ions.
1.2.3 Applications of conductance measurements: determination of degree of ionization and ionization
constant of weak electrolyte, solubility and solubility product of sparingly soluble salts, ionic product of
water. (Numericals expected).
1.2.4 Transference number and its experimental determination using Moving boundary method.
(Numericals expected). Factors affecting transference number.
Chemical Bonding
2.1 Non-Directional Bonding (4L)
2.1.1 Ionic Bond: Conditions for the Formation of Ionic Bond.
2.1.2 Types of Ionic Crystals
2.1.3 Radius Ratio Rules
2.1.4 Lattice Energy, Borne-Lande Equation
2.1.5 Kapustinski Equation
2.1.6 Born-Haber Cycle and its Application
2.2. Directional Bonding: Orbital Approach. (6L)
2.2.1 Covalent Bonding The Valence Bond Theory- Introduction and basic tenets.
2.2.2 Interaction between two hydrogen atoms and the Potential energy diagram of the resultant system.
2.2.3 Corrections applied to the system of two hydrogen atoms- Formation of H2.
2.2.4 Homonuclear diatomic molecules from He2 to Ne2
2.2.5 Resonance and the concept of Formal Charge; Rules for Resonance or Canonical structures.
2.2.6 Bonding in Polyatomic Species: The role of Hybridization. And types of hybrid orbitals-sp, sp2, sp
3
, sp3d, sp2d2 and sp2d, sp3d2.
2.2.7 Equivalent and Non-Equivalent hybrid orbitals.
2.2.8 Contribution of a given atomic orbital to the hybrid orbitals (with reference to sp3 hybridisation as in
CH4, NH3 and H2O and series like NH3, PH3, AsH3, BiH3)
2.3 Molecular Orbital Theory (5L)
2.3.1. Comparing Atomic Orbitals and Molecular Orbitals.
2.3.2. Linear combination of atomic orbitals. to give molecular orbitals LCAO-MO approach for diatomic

DEPARTMENT OF CHEMISTRY
homonuclear molecules).
2.3.4. Wave mechanical treatment for molecular orbitals (H2 + and H2)
2.3.4 Molecular orbital Theory and Bond Order and magnetic property: with reference to O2, O2+, O2-,
O22- (Problems and numerical problems expected wherever possible).
Unit III: Organic Chemistry
3.1.1. Reactions and reactivity of halogenated hydrocarbons: [4L]
3.1.1. Alkyl halides: Nucleophilic substitution reactions: SN1, SN2 and SNi mechanisms with
stereochemical aspects and factors affecting nucleophilic substitution reactions-nature of substrate,
solvent, nucleophilic reagent and leaving group.
3.1.2. Aryl halides: Reactivity of aryl halides towards nucleophilic substitution reactions. Nucleophilic
aromatic substitution (SNAr) addition-elimination mechanism and benzyne mechanism.
3.1.2.Organomagnesium and Organolithium compounds: [3L]
Nomenclature, nature, type and reactivity of carbon-metal bond. Preparation using alkyl / aryl halide.
Structure, stability and reactions with compounds containing acidic hydrogen, carbonyl compounds, CO 2,
cyanides and epoxides.
3.2 Alcohols, phenols and epoxides: [8L]
3.2.1Alcohols: Nomenclature, Preparation: Hydration of alkenes, hydrolysis of alkyl halides, reduction of
aldehydes and ketones, using Grignard reagent. Properties: Hydrogen bonding, types and effect of
hydrogen bonding on different properties. Acidity of alcohols, Reactions of alcohols.
3.2.2. Phenols: Preparation, physical properties and acidic character. Comparative acidic strengths of
alcohols and phenols, resonance stabilization of phenoxide ion. Reactions of phenols.
3.2.3. Epoxides: Nomenclature, methods of preparation and reactions of epoxides: reactivity, ring
opening reactions by nucleophiles (a) In acidic conditions: hydrolysis, reaction with halogen halide,
alcohol, hydrogen cyanide. (b) In neutral or basic conditions: ammonia, amines, Grignard reagents,
alkoxides.

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry II
Program Code: 1S00143 Course Code: USCH302
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-2018)
Class: S. Y. B. Sc. Semester : III

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Know the effect of temperature on rate of reaction.
CO2 Explain kinetics of complex chemical reactions.
CO3 Understand Nernst distribution law and its applications in extraction.
CO3 Know the chemistry of B, Si, Ge and Nitrogen family.
CO4 Illustrate the importance of BORAX and Born-Haber process.
CO5 Outlines the preparation methods of carbonyl compounds.
CO6 Explain the mechanism of nucleophilic addition.
CO7 Understand the use of carbonyl compounds in the preparation of other chemical compounds.
CO8 Write the mechanism of Name reactions based on carbonyl compounds.
CO9 Illustrate the concept of active methylene compounds.

Unit I: Physical Chemistry

1.1 Chemical Kinetics-II (7L)
1.1.1 Types of Complex Chemical reactions: Reversible or opposing, consecutive and parallel reactions
(No derivations, only examples expected), Thermal chain reactions: H. and Br. reaction. (Only steps
involved, no kinetic expression expected).
1.1.2 Effect of temperature on the rate of reaction, Arrhenius equation, Concept of energy of activation
(Ea). (Numericals expected).
1.1.3 Theories of reaction rates: Collision theory and activated complex theory of bimolecular reactions.
Comparison between the two theories (Qualitative treatment only).
1.2 Solutions: (8 L)
1.2.1 Thermodynamics of ideal solutions: Ideal solutions and Raoult’s law, deviations from Raoult’s law–

DEPARTMENT OF CHEMISTRY
non-ideal solutions. Vapour pressure-composition and temperature -composition curves of ideal and non-
ideal solutions. Distillation of solutions. Lever rule. Azeotropes.
1.2.2 Partial miscibility of liquids: Critical solution temperature; effect of impurity on partial miscibility
of liquids with respect to Phenol-Water, Triethanolamine – Water and Nicotine –Water systems.
1.2.3 Immiscibility of liquids- Principle of steam distillation.
1.2.4 Nernst distribution law and its applications, solvent extraction.
Unit II: Inorganic Chemistry
2. Selected topics on p block elements (15L)
2.1 Chemistry of Boron compounds
2.1.1 Electron deficient compounds – BH3, BF3, BCl3 with respect to Lewis acidity and applications.
2.1.2 Preparation of simple boranes like diborane and tetraborane.
2.1.3 Structure and bonding in diborane and tetraborane (2e-3c bonds)
2.1.4 Synthesis of Borax.
2.2 Chemistry of Silicon and Germanium
2.2.1 Silicon compounds: Occurrence , Structure and inertness of SiO2
2.2.2 Preparation of structure of SiCl4
2.2.3 Occurrence and extraction of Germanium
2.2.4 Preparation of extra pure Silicon and Germanium
2.3 Chemistry of Nitrogen family
2.3.1 Trends in chemical reactivity - Formation of hydrides, halides, oxides with special reference to
oxides of nitrogen.
2.3.2 Oxides of nitrogen with respect to preparation and structure of NO, NO2, N2O and N2O4.
2.3.3 Synthesis of ammonia by Bosch – Haber process.
Unit III: Organic Chemistry
Carbonyl Compounds: [15L]
3.1 Nomenclature of aliphatic, alicyclic and aromatic carbonyl compounds. Structure, reactivity of
aldehydes and ketones and methods of preparation; Oxidation of primary and secondary alcohols using
PCC, hydration of alkynes, action of Grignard reagent on esters, Rosenmund reduction, Gattermann –
Koch formylation and Friedel Craft acylation of arenes.
3.2 General mechanism of nucleophilic addition, and acid catalyzed nucleophilic addition reactions.
3.3 Reactions of aldehydes and ketones with NaHSO3, HCN, RMgX, alcohol, amine, phenyl hydrazine, 2,

DEPARTMENT OF CHEMISTRY
4-Dinitrophenyl hydrazine, LiAlH4 and NaBH4.
3.4 Mechanisms of following reactions: Benzoin condensation, Knoevenagel condensation, Claisen-
Schmidt and Cannizzaro reaction.
3.5 Keto-enol tautomerism: Mechanism of acid and base catalysed enolization.
3.6 Active methylene compounds: Acetylacetone, ethyl acetoacetate diethyl malonate, stabilised enols.
Reactions of Acetylacetone and ethyl acetoacetate (alkylation, conversion to ketone, mono- and
dicarboxylic acid)

Reference Books for USCH301 & USCH302:

Unit I:
1. Barrow, G.M. Physical Chemistry Tata McGraw‐ Hill (2007).
2. Castellan, G.W. Physical Chemistry 4th Ed. Narosa (2004).
3. Kotz, J.C., Treichel, P.M. & Townsend, J.R. General Chemistry Cengage Learning India Pvt. Ltd.,
New Delhi (2009).
4. Mahan, B.H. University Chemistry 3rd Ed. Narosa (1998).
5. Petrucci, R.H. General Chemistry 5th Ed. Macmillan Publishing Co., New York (1985).
6. K. L. Kapoor A textbook of Physical Chemistry3rd Ed. vol.1,2Macmillan Publishing Co., New Delhi
(2001)
Unit II:
6. Bruce H. Mahan, University Chemistry, Narosa publishing house pg. 611 to 683.
7. R. Gopalan, Universities Press India Pvt. Ltd. Inorganic Chemistry for Undergraduates.
8. Chemistry of Transition Elements Pg. - 608 – 679.
9. J. D. Lee, 4th Edn. Concise Inorganic Chemistry, ELBS, The group III elements Pg. 359- 648.
10. D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press (1999) page
325-446.
11. Ramesh Kapoor and R.S. Chopra, Inorganic Chemistry, R. Chand publishers, New Delhi.
12. CNR Rao edited, University General Chemistry, 513-578.
13. James E. Huheey, Inorganic Chemistry: Principles of Structure and Reactivity,
14. Emeleus and Anderson, Modern Aspects of Inorganic Chemistry, page no. 435-463.
15. Cotton and Wilkinson, Advanced Inorganic Chemistry, 3rd. Edition.
16. Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt, Ltd. (2002).

DEPARTMENT OF CHEMISTRY
17. Puri, Sharma and Kalia, Milestone publishers, Principles of Inorganic Chemistry, page 416-628.
18. Bruce H. Mahan, University Chemistry, Narosa publishing house.
19. R. Gopalan, Universities Press India Pvt. Ltd. Inorganic Chemistry for Undergraduates.
20.J. D. Lee, 4th Edn., Concise Inorganic Chemistry, ELBS
21.D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press (1999)
22. Ramesh Kapoor and R.S. Chopra, Inorganic Chemistry, R. Chand publishers, New Delhi.
23.CNR Rao edited, University General Chemistry
24.James E. Huheey, Inorganic Chemistry: Principles of Structure and Reactivity,
25.Emeleus and Anderson, Modern Aspects of Inorganic Chemistry
26. Cotton and Wilkinson, Advanced Inorganic Chemistry, 3rd. Edition.
27. Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt, Ltd. (2002).
28.Puri, Sharma and Kalia, Milestone publishers, Principles of Inorganic Chemistry
Unit III:
1. Morrison, R. T. and Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).2012
2. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
3. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural Products),
Dorling Kindersley (India) Pvt. Ltd. (Pearson Education)
4. Mc Murry, J.E. Fundamentals of Organic Chemistry, 7th Ed. Cengage Learning India Edition, 2013.
5. Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, Oxford University Press.
6. Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.
7. Comprehensive Organic Chemistry- The synthesis and reactions of Organic Compounds, Derek barton
, W. David Ollis.
8. Kalsi, P. S. Textbook of Organic Chemistry 1st Ed., New Age International (P) Ltd. Pub.
9. Eliel, E. L. and Wilen, S. H. Stereochemistry of Organic Compounds, Wiley: London, 1994.
10. Kalsi, P. S. Stereochemistry Conformation and Mechanism, New Age International, 2005

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Basics in analytical Chemistry Paper III
Program Code: 1S00143 Course Code: USCH303
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-2018)
Class: S. Y. B. Sc. Semester : III

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Know the role and importance of analytical chemistry in various fields.
CO2 Learn basic terms used in analytical chemistry and their significance.
CO3 Understand purpose of chemical analysis and classification of chemical analysis.
CO4 Understand the importance of sampling, sampling techniques and statistical data treatment.
CO5 Demonstrate classical methods of analysis.
CO6 Learn the use of various instruments for chemical analysis.
CO7 Know the basics of absorption spectroscopy.

Unit I- Introduction to Analytical Chemistry and Statistical Treatment of analytical data-I (15 L)
1.1. Role of Analytical Chemistry (9 L)
1.1.1. Language of analytical chemistry: important terms and their significance in Analytical Chemistry.
1.1.2. Purpose of Chemical Analysis; Analysis Based (i) On the nature of information required:
(Proximate, Partial, Trace, Complete Analysis) and (ii) On the size of the sample used (Macro, semi-
micro and micro analysis)
1.1.3. Classical and Non-Classical Methods of Analysis; their types and importance.
1.2. Significance of Sampling in Analytical Chemistry
1.2.1. Terms involved in Sampling
1.2.2. Types of Sampling
1.2.3. Sampling techniques
1.3. Results of Analysis. (6 L)

DEPARTMENT OF CHEMISTRY
1.3.1. Errors in Analysis and their types
1.3.2. Precision and Accuracy in Analysis
1.3.3. Corrections for Determinate Errors
(Problems including Numericals expected wherever required)
Unit II- Classical Methods of Analysis(15 L)
2. Classical Methods of Analysis. (04 L)
2.1. Titrimetric Methods
2.1.1. Terms involved in Titrimetric methods of analysis. Comparing volumetry and Titrimetry.
2.1.2. The Conditions suitable for titrimetry.
2.1.3. Types of titrimetry – Neutralisation (Acidimetry, alkalimetry), Redox, (Iodometry, Iodimetry,)
Precipitation and Complexometric titrations and indicators used in these titrations
2.1.4. Tools of Titrimetry: Graduated glasswares and Callibration
2.2. Standard solutions (Primary and Secondary standards in Titrimetry) and Calculations in Titrimetry.
2.3. Neutralisation Titrations (04 L)
2.3.1. Concept of pH and its importance in Neutralisation Titrations
2.3.2. End point and Equivalence point of Neutralisation titrations
2.3.3. Determination of End point by using
i. Indicators causing colour change
ii. Change in potential, (by potentiometry)
iii. Change in conductance (by conductometry)
2.3.4. Construction of titration curve (on the basis of change in pH )of a titration of
i. Strong acid-weak base
ii. Strong base-weak acid
2.4. Gravimetric analysis ( 06 L)
2.4.1. General Introduction to Gravimetry.
2.4.2. Types of Gravimetric Methods –
2.4.3. Precipitation Gravimetry:
i. Steps involved in precipitation gravimetry analysis
ii. Conditions for precipitation
iii. Completion of precipitation,
iv. Role of Digestion, Filtration, Washing, Drying Ignition of precipitate.

DEPARTMENT OF CHEMISTRY
v. Applications of Gravimetric Analysis: Determination of sulfur in organic compounds; Estimation of
Nickel in Cu-Ni alloy using dimethyl glyoxime; Determination of Aluminum by converting it to its oxide.
Unit III: Instrumental Methods-I [15 L]
3. Basic Concepts in Instrumental methods (03 L)
3.1. Relation between the analyte, stimulus and measurement of change in the observable property.
3.2. Block Diagram of an Analytical instrument.
3.3. Types of Analytical Instrumental methods based on
i. Optical interactions (e.g. Spectrometry: uv-visible, Polarimetry)
ii. Electrochemical interactions (e.g. Potentiometry, Conductometry,)
iii. Thermal interactions (e.g. Thermogravimetry)
3.4. Spectrometry (07 L)
3.4.1. Interaction of electromagnetic radiation with matter: Absorption and Emission spectroscopy
3.4.2. Basic Terms: Radiant Power, Absorbance, Transmittance, Monochromatic light, Polychromatic
light, Wavelength of maximum absorbance, Absorptivity and Molar Absorbtivity
3.4.3. Statement of Beer’s Law and Lambert’s Law, Combined Mathematical Expression of Beer -
Lambert’s Law, Validity of Beer-Lambert’s Law, Deviations from Beer-Lambert’s Law ((Real deviations,
Instrumental deviations and Chemical deviations) (Numerical problems based on Beer-Lambert’s Law)
3.4.4. Instrumentation for absorption spectroscopy: Colorimeters and Spectrophotometers
3.4.5. Block Diagrams for Single beam and Colorimeter, and Spectrophotometer (Principles, Construction
and working-Details of Components expected i. e. , source ,Sample holder , Filters/Monochromators,
Detectors such as Photomultiplier tube)
3.4.6. Applications of UV-Visible Spectrophotometry (02 L)
(a) Qualitative analysis such as Identification of functional groups in Organic compounds ,Chromophores
and Auxochrome, cis and trans isomers
(b) Quantitative analysis by Calibration curve method and
3.4.7. Photometric Titrations: Principle, Instrumentation, Types of Photometric titration Curves with
examples. (03L)
References:
1. Instrumental Analysis by Douglas A. Skoog, F. James Holler, Stanley R. Crouch
2. Instrumental methods of analysis by Willard, H.H.; Merritt, L.L. Jr.; Dean, J.A.; Settle,7th Edition
3. Fundamental of Analytical Chemistry by Douglas A. Skoog, West, F. James Holler, S. R. Crouch

DEPARTMENT OF CHEMISTRY
4. Modern Analytical Chemistry by David Harvey, McGraw-Hill Higher Education
5. Skoog et al. “Fundamentals of Analytical chemistry" Cengage Learning, Eight Edition, chapter 13, 14
and 15
6. Day and Underwood, “Quantitative analysis" prentice hall 1991, chapter3
7. S.M. Khopkar, “ Basic Concepts of Analytical Chemistry”, IInd Edition New Age International
Publisher
8. Gary D. Christan,” Analytical Chemistry”, VIth Edition, Wiley Students Edition, Chapter No 8,9,10
9. Fundamental of Analytical Chemistry by Douglas A. Skoog, West, F. James Holler, S. R. Crouch
10. Modern Analytical Chemistry , David Harvey ( page numbers 232 -265)
11. Instrumental Methods of Chemical Analysis by Gurdeep R. Chatwal , Sham K. Anand pp 2.107-2.148
12. Principles of Instrumental Analysis by Skoog, Holler, Nieman, 5th Edition pp 143-172.
13. Instrumental Methods of Analysis by Willard, Merritt, Dean, Settle 7th Edition pp 118-181.

DEPARTMENT OF CHEMISTRY
Semester End Theory Examinations:

Scheme of Examination
Semester End Theory Examinations:

There will be a Semester-end external theory examination of 100 marks for each of the courses
USCH301, USCH302, USCH303 of Semester III to be conducted by College.

Duration: The examinations shall be of 3 Hours duration.

1. Theory Question Paper Pattern:

a) There shall be FIVE questions. The Q.1 shall be of objective type for 20 marks based on the
entire syllabus consisting of multiple choice questions, match the following, true or false etc. The
questions Q.2, Q.3 and Q.4 shall be of 20 marks, each based on the unit I (Physical Chemistry),
unit II (Inorganic Chemistry) and Unit III (Organic Chemistry) respectively. Q.5 is based on all
the three units.
b) All the questions are compulsory. The questions Q.2, Q.3, Q.4, Q. 5 shall have internal
choices within the questions. Including the choices, the marks for each question shall be of 0
c) The questions Q.1, Q.2, Q.3, Q.4 and Q.5 may be subdivided into sub-questions as A, B, C, D,
E & F.

Q.1 Based On Unit I, II & III

(A) Select the correct option and complete the following sentences. (any twelve) 12

(B) State whether the following statements are true or false. (any three) 03
(C) Match the column. (any five) 05

Q. 2 Attempt any four from A or A /B or B/C or C Unit I Marks 20

Q. 3 Attempt any four from A or A /B or B/C or C Unit II Marks 20
Q. Attempt any four from A or A /B or B/C or C Unit III Marks 20
Q. 5 Attempt any four from A/B/C/D/E/F Unit I, II & III Marks 20

DEPARTMENT OF CHEMISTRY
DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Chemistry Practical Based on Paper I, II & III
Program Code: 1S00143 Course Code: USCHP1, USCHP2 & USCHP3
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Year: S. Y. B. Sc. Semester : III

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Understand the use of conductometer to determination dissociation constant of weak acid.
CO2 Calculate energy of activation of acid catalysed ester hydrolysis.
CO3 Analyse inorganic salts qualitatively by semi micro method.
CO4 Estimate the hardness of water.
CO5 Learn the preparation of single step organic compounds and their purification.
CO6 Know the tools used in analytical chemistry.
CO7 Determine the Cu ions in solution by using colorimeter.
CO8 Gravimetric estimation of Ba2+ ions & Ni2+ ions.

Unit I: Physical Chemistry

1. To verify Ostwald’s dilution law for weak acid conductometrically.
2. To determine dissociation constant of weak acid conductometrically.
3. To determine the critical solution temperature (CST) of phenol - Water System.
4. Determination of energy of activation of acid catalyzed hydrolysis of methyl acetate.
5. To investigate the reaction between K2S2O8 and KI with equal initial concentrations of the reactants
6. To determine solubility of sparingly soluble salts (any two) conductometrically.
Unit II: Inorganic Chemistry
1. Identification of cations in a given mixture and Analytically separating them [From a mixture
containing not more than two of the following: Pb(II), Ba(II), Ca(II), Sr(II), Cu(II), Cd(II), Mg(II), Zn(II),
Fe(II), Fe(III), Ni(II), Co(II) Al(III), Cr(III).
2. Crystallization of potassium iodate and to estimate its purity before and after the separation.

DEPARTMENT OF CHEMISTRY
3. Estimation of total hardness
4. Investigation of the reaction between Copper sulphate and Sodium Hydroxide. (Standard EDTA
solution to be provided to the learner).
Unit III: Organic Chemistry
Short organic preparation and their purification: Use 0.5-1.0g of the organic compound. Purify the
product by recrystallization. Report theoretical yield, percentage yield and melting point of the purified
product.
Preparation of:
1. Cyclohexanone oxime from cyclohexanone.
2. Glucosazone from dextrose or fructose
3. Tribromoaniline from aniline.
4. β-Naphthyl benzoate
5. m-Dinitrobenzene from nitrobenzene
6. Phthalic anhydride from phthalic acid by sublimation
7. Acetanilide from aniline
8. p-Bromoacetanilide from acetanilide
9. Iodoform from acetone
(Any eight preparations)
References:
Unit I:
1. Khosla B.D., Garg V.C. and Gulati A., Senior Practical Physical Chemistry, R. Chand and Co., New
Delhi (2011).
2. Garland C. W., Nibler J.W. and Shoemaker D.P., Experiments in Physical Chemistry, 8th Ed.,
McGraw-Hill, New York (2003).
3. Halpern A.M. and McBane G.C., Experimental Physical Chemistry, 3rd Ed., W.H. Freeman and Co.,
New York (2003).
4. Athawale V.D. and Mathur P., Experimental Physical Chemistry, New Age International, New Delhi
(2001)
Unit II:
1. Practical Inorganic Chemistry by G. Marr and B. W. Rockett van Nostrand Reinhold Company (1972)
Unit III:

DEPARTMENT OF CHEMISTRY
1. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)
2. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry: Preparation and
Quantitative Analysis, University Press (2000). Mann, F.G. & Saunders, B.C. Practical Organic
Chemistry, Pearson Education (2009).
3. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed.,
Pearson (2012).
4. Vogel, A.I., Tatchell, A.R., Furnis, B.S., Hannaford, A.J. & Smith, P.W.G., Textbook of Practical
Organic Chemistry, Prentice-Hall, 5th edition, 1996.

: Question Paper Pattern :

Each Chemistry Practical Paper is of 50 Marks and 3 hours duration.

Maximum Marks: 50 Marks
Time: 3 Hours
Note: 1) Attempt all Questions
1. Perform given experiment and tabulate the result as per guidelines. 40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
 Detailed scheme of marking of Preparation /Estimation Experiment.

Observation 26
Reaction 02
Calculation 08
Systematic work 04
Total 40

 Detailed scheme of marking of Instrumental/Non-instrumental Physical or Analytical

Chemistry Experiment.

Technique 04 marks
Observations 12 marks
Calculation 06 marks
Graph 06 marks
Accuracy 12 marks
Total 40 marks

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry I
Program Code: 1S00144 Course Code: USCH401
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-2018)
Class: S. Y. B. Sc. Semester : IV

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Comprehend types of cells, electrodes and thermodynamics of electrochemical reactions.
CO2 Understand the Gibb’s phase rule and its thermodynamic derivation.
CO3 Know the comparative chemistry of transition metals.
CO4 Learn about theories of formation of coordination compounds and their applications.
CO5 Know the methods used for preparation of carboxylic acids.
CO6 Illustrate the factors affecting on acidity
CO7 Learn the chemical reactions shown by carboxylic acids.
CO8 Write the mechanism of acyl nucleophilic substitution.
CO9 Explain the acid derivatives and related reactions.
CO10 Know reactions and preparation methods of aromatic sulphonic acids.

Unit I: Physical Chemistry

1.1Electrochemistry-II: (8 L)
1.1.1 Electrochemical conventions, Reversible and irreversible cells.
1.1.2 Nernst equation and its importance, Types of electrodes, Standard electrode potential,
Electrochemical series (Numericals expected).
1.1.3 Thermodynamics of a reversible cell, calculation of thermodynamic properties: ΔG, ΔH and ΔS
from EMF data. (Numericals expected)
1.1.4 Calculation of equilibrium constant from EMF data. (Numericals expected)
1.1.5 Concentration cells with transference and without transference. Liquid junction potential and salt
bridge.
1.1.6 pH determination using hydrogen electrode and quinhydrone electrode.(Numericals expected)

DEPARTMENT OF CHEMISTRY
1.2 Phase Equilibria: (7L)
1.2.1 Phases, components and degrees of freedom of a system, criteria of phase equilibrium. Gibbs Phase
Rule and its thermodynamic derivation.
1.2.2 Derivation of Clausius – Clapeyron equation and its importance in phase equilibria. (numericals
expected)
1.2.3 Phase diagrams of one-component systems (water and sulphur).
1.2.4 Two component systems involving eutectics, congruent and incongruent melting points (lead-silver
system).
Unit-II: Inorganic Chemistry
2.1 Comparative Chemistry of the transition metals (9 L)
2.1.1 Position in the periodic table; Natural occurrence principal ores and minerals;
2.1.2 Significance of special stability of d0, d5and d10 leading to variable oxidation states; Unusual
oxidation states and their stabilities in aqueous solutions (with special reference to vanadium, and
chromium.)
2.1.3 Origin of colour for transition metals and their compounds: such as reflectivity, surface coatings,
particle size, packing density for metals and nature of d-orbitals, number of electrons in the d-orbitals,
geometry, and ability for charge transfer).
2.1.4 Magnetic properties of transition metal compounds: Origin of magnetism-spin and orbital motion of
electrons; equation for spin only and spin-orbital magnetism in terms of Bohr magnetons (No derivation
of relevant equations expected); Reasons for quenching of orbital moments.
2.1.5 Chemistry of Titanium and vanadium: properties of Oxides and chlorides; use in titrimetric analysis
2.1.6 Qualitative tests for transition metal ions: General considerations in devising tests (with reference to
Chromium, Manganese, iron, Cobalt Nickel and Copper)
2.2 Coordination Chemistry : (6 L)
2.2.1 Introduction to Chemistry of Coordination Compounds
i. Historical perspectives: Early ideas on coordination compounds
ii. Basic terms and nomenclature.
iii. Types of ligands
iv. Isomerism :General Types with special reference to stereoisomerism of coordination compounds
(C.N=6)
v. Evidence for the formation of coordination compounds,

DEPARTMENT OF CHEMISTRY
2.2.2. Theories of coordination compounds
i. Werner’s Theory of coordination compounds,
ii. Effective atomic number rule.
iii. Eighteen electron Rule
2.2.3. Nature of the Metal-Ligand Bond:
i. Valence Bond Theory; Hybridisation of the central metal orbitals-sp3, sd3/d3s sp3d2/d2sp3, sp2d,
ii. Inner and outer orbital complexes of .(suitable examples of Mn(II), Fe(II), Fe(III), Co(II)/Co(III),
Ni(II), Cu(II), Zn(II) complexes with ligands like aqua, ammonia CN and halides may be used)
iii. Limitations of V.B.T
2.2.4. Application of coordination compounds.
Unit III: Organic Chemistry
3.1 Carboxylic Acids and their Derivatives :(11 Lectures)
3.1.1. Nomenclature, structure and physical properties, acidity of carboxylic acids, effects of substituents
on acid strength of aliphatic and aromatic carboxylic acids.
3.1.2. Preparation of carboxylic acids: oxidation of alcohols and alkyl benzene, carbonation of Grignard
and hydrolysis of nitriles.
3.1.3. Reactions: Acidity, salt formation, decarboxylation, Reduction of carboxylic acids with LiAlH 4,
diborane, Hell-Volhard-Zelinsky reaction, Conversion of carboxylic acid to acid chlorides, esters, amides
and acid anhydrides and their relative reactivity.
3.1.4. Mechanism of nucleophilic acyl substitution and acid-catalysed nucleophilic acyl substitution.
Interconversion of acid derivatives by nucleophilic acyl substitution.
3.1.5. Mechanism of Claisen condensation and Dieckmann condensation.
3.2 Sulphonic acids: [4L]
Nomenclature, preparation of aromatic sulphonic acids by sulphonation of benzene (with mechanism),
toluene and naphthalene, Reactions: Acidity of arene sulfonic acid, Comparative acidity of carboxylic
acid and sulfonic acids. Salt formation, desulphonation. Reaction with alcohol, phosphorous
pentachloride, IPSO substitution.

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
General Chemistry II
Program Code: 1S00144 Course Code: USCH402
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-2018)
Class: S. Y. B. Sc. Semester : IV

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Explain laws of crystallography and types of crystals.
CO2 Learn determination of crystal structure using X-rays.
CO3 Know about catalyst, their types and catalytic action.
CO4 Explain behaviour of ions in aqueous medium.
CO5 Discuss the uses of H2SO4, HNO3, H3PO4 and their environmental impact.
CO6 Learn about basic nature of amines and factors affecting on it.
CO7 Know the preparation methods and reactions shown by amines.
CO9 Learn preparation of diazonium salts, their reactions and applications in dyes.
C10 Know about heterocyclic chemical compounds, their structures and nomenclature.

Unit I: Physical Chemistry

1.1 Solid State: (7L)
1.1.1 Recapitulation of laws of crystallography and types of crystals
1.1.2 Characteristics of simple cubic, face centered cubic and body centered cubic systems, interplanar
distance in cubic lattice (only expression for ratio of interplanar distances are expected)
1.1.3 Use of X-rays in the study of crystal structure, Bragg’s equation (derivation expected), X-rays
diffraction method of studying crystal lattice structure, structure of NaCl and KCl. Determination of
Avogadro’s number (Numericals expected)
1.2 Catalysis: (8 L)
1.2.1 Types of catalysis, catalytic activity, specificity and selectivity, inhibitors, catalyst poisoning and
deactivation

DEPARTMENT OF CHEMISTRY
1.2.2 Mechanisms and kinetics of acid-base catalyzed reactions, effect of pH.
1.2.3 Mechanisms and kinetics of enzyme catalyzed reactions (Michaelis-Menten equation)
1.2.4 Effect of particle size and efficiency of nanoparticles as catalyst.
Unit II: Inorganic Chemistry
2 Ions in aqueous medium
2.1. Acidity of Cations and Basicity of Anions
i. Hydration of Cations; Hydrolysis of Cations predicting degree of hydrolysis of Cations-effect of Charge
and Radius.
ii.Latimer Equation. Relationship between pKa, acidity and z2/r ratios of metal ions graphical Presentation
iii. Classification of cations on the basis of acidity category – Non acidic, Moderately acidic, strongly
acidic, very strongly acidic with pKa values range and examples
iv. Hydration of Anions; Effect of Charge and Radius; Hydration of anions concept, diagram
classification on the basis of basicity.
2.2. Uses and Environmental Chemistry of volatile Oxides and oxo-acids
i. Physical properties of concentrated oxo-acids like sulfuric, Nitric and Phosphoric acid
ii. Uses and environments aspects of these acids
Unit III: Organic Chemistry
Nitrogen containing compounds and heterocyclic compounds: (7Lectures)
3.1 Amines:
Nomenclature, effect of substituent on basicity of aliphatic and aromatic amines;
3.1.1. Preparation: Reduction of aromatic nitro compounds using catalytic hydrogenation, chemical
reduction using Fe-HCI, Sn-HCl, Zn-acetic acid, reduction of nitriles, ammonolysis of halides, reductive
amination , Hofmann bromamide reaction.
3.1.2. Reactions- Salt Formation, N-acylation, N-alkylation, Hofmann’s exhaustive methylation
(HEM),Hofmann-elimination reaction, reaction with nitrous acid, carbylamine reaction, Electrophilic
substitution in aromatic amines: bromination, nitration and sulphonation.
3.2 Diazonium Salts:
Preparation and their reactions/synthetic application - Sandmeyer reaction, Gattermann reaction, Gomberg
reaction, Replacement of diazo group by -H,-OH. Azo coupling with phenols, naphthols and aromatic
amines, reduction of diazonium salt to aryl hydrazine and hydroazobenzene
3.3 Heterocyclic Compounds: (8 Lectures)

DEPARTMENT OF CHEMISTRY
3.3.1. Classification, nomenclature, electronic structure, aromaticity in 5-numbered and 6-membered rings
containing one heteroatom;
3.3.2. Synthesis of Furan, Pyrrole (Paal-Knorr synthesis, Knorr pyrrole synthesis, and Hantzsch
synthesis), Thiophene, Pyridine (Hantzsch synthesis),
3.3.3. Reactivity of furan, pyrrole and thiophene towards electrophilic substitution reactions on the basis
of stability of intermediate and of pyridine on the basis of electron distribution. Reactivity of pyridine
towards nucleophilic substitution on the basis of electron distribution.
3.3.4. Reactions of furan, pyrrole and thiophene: halogenation, nitration, sulphonation, Vilsmeier-Haack
reaction, Friedel-Crafts reaction. Furan: Diels-Alder reaction, Ring opening. Pyrrole: Acidity and basicity
of pyrrole. Comparison of basicity of pyrrole and pyrrolidine.
3.3.5. Pyridine: Basicity. Comparison of basicity of pyridine, pyrrole and piperidine. Sulphonation of
pyridine (with and without catalyst), reduction and action of sodamide (Chichibabin reaction).
Reference Books for USCH401 & USCH402:
Unit I:
1. Barrow, G.M. Physical Chemistry Tata McGraw‐ Hill (2007).
2. Castellan, G.W. Physical Chemistry 4th Ed. Narosa (2004).
3. Kotz, J.C., Treichel, P.M. & Townsend, J.R. General Chemistry Cengage Learning India Pvt. Ltd.,
New Delhi (2009).
4. Mahan, B.H. University Chemistry 3rd Ed. Narosa (1998).
5. Petrucci, R.H. General Chemistry 5th Ed. Macmillan Publishing Co., New York (1985).
6. K .L. Kapoor A textbook of Physical Chemistry3rd Ed. vol.1,2 Macmillan Publishing Co., New Delhi
(2001)
Unit II:
7. Bruce H. Mahan, University Chemistry, Narosa publishing house pg. 611 to 683.
8. R. Gopalan, Universities Press India Pvt. Ltd. Inorganic Chemistry for Undergraduates.
9. Chemistry of Transition Elements Pg.- 608 – 679 .
10. J. D. Lee, 4th Edn., Concise Inorganic Chemistry, ELBS, The group III elements Pg. 359- 648.
11. D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press (1999) page
325-446.
12. Ramesh Kapoor and R.S. Chopra, Inorganic Chemistry, R. Chand publishers, New Delhi.
13. CNR Rao edited, University General Chemistry, 513-578.

DEPARTMENT OF CHEMISTRY
14. James E. Huheey, Inorganic Chemistry: Principles of Structure and Reactivity,
15. Emeleus and Anderson, Modern Aspects of Inorganic Chemistry, page no. 435-463.
16. Cotton and Wilkinson, Advanced Inorganic Chemistry, 3rd. Edition.
17. Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt,. Ltd. (2002).
18. Puri, Sharma and Kalia, Milestone publishers, Principles of Inorganic Chemistry, page 416-628.
19. Bruce H. Mahan, University Chemistry, Narosa publishing house.
20. R. Gopalan, Universities Press India Pvt. Ltd. Inorganic Chemistry for Undergraduates.
21. J. D. Lee, 4th Edn., Concise Inorganic Chemistry, ELBS
22. D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press (1999)
23. Ramesh Kapoor and R.S. Chopra, Inorganic Chemistry, R. Chand publishers, New Delhi.
24. CNR Rao edited, University General Chemistry
25. James E. Huheey, Inorganic Chemistry: Principles of Structure and Reactivity,
26. Emeleus and Anderson, Modern Aspects of Inorganic Chemistry
27. Cotton and Wilkinson, Advanced Inorganic Chemistry, 3rd. Edition.
28. Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt,. Ltd. (2002).
29. Puri, Sharma and Kalia, Milestone publishers, Principles of Inorganic Chemistry
Unit III:
1. Morrison, R. T. and Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education).2012
2. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
3. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural Products),
Dorling Kindersley (India) Pvt. Ltd. (Pearson Education)
4. Mc Murry, J.E. Fundamentals of Organic Chemistry, 7th Ed. Cengage Learning India Edition, 2013.
5. Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, Oxford University Press.
6. Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.
7. Comprehensive Organic Chemistry- The synthesis and reactions of Organic Compounds, Derek barton
W. David Ollis.
8. Kalsi, P. S. Textbook of Organic Chemistry 1st Ed., New Age International (P) Ltd. Pub.
9. Eliel, E. L. and Wilen, S. H. Stereochemistry of Organic Compounds, Wiley: London, 1994.
10. Kalsi, P. S. Stereochemistry Conformation and Mechanism, New Age International, 2005

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Basics in analytical Chemistry Paper III
Program Code:1S00144 Course Code: USCH403
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-2018)
Class: S. Y. B. Sc. Semester : IV

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Aware about different analytical separation techniques and their importance.
CO2 Use chromatographic techniques for separation of mixture.
CO3 Know the applications of the various instrumental methods.
CO4 Learn the nature of chemical reactions that influence potential of a given cell.
CO5 Explain various types of electrodes or half cells.
CO6 Use statistical methods in chemical analysis.
CO7 Represent graphical data and to draw best fitting straight line.
CO8 Understand accuracy, precision, mean, mode, median etc.

Unit –I -Methods of separation ( 15 L)

1. Separation Techniques in Analytical Chemistry (02 L)
1.1. An Introduction to Analytical Separations and its importance in analysis.
1.2. Estimation of an analyte without effecting separation.
1.3. Types of separation methods
1.3.1. Based on Solubilities (Precipitation, Filtration Crystallisation)
1.3.2. Based on Gravity- Centrifugation
1.3.3. Based on volatility-Distillation ;
1.3.4. Based on Electrical effects-Electrophoresis
1.3.5. Based on retention capacity of a Stationary Phase -Chromatography;
1.3.6. Based on distribution in two immiscible phases-Solvent Extraction;
1.3.7. Based on capacity to exchange with a resin-Ion Exchange;

DEPARTMENT OF CHEMISTRY
1.4. Electrophoresis: Principles, Basic Instrumentation, Working and Application in separation of
biomolecules like enzymes and DNA. (02L)
1.5. Solvent extraction (06 L)
1.5.1. Introduction, Nernst distribution Law, Distribution Ratio, Partition Coefficient.
1.5.2. Conditions of extraction: Equilibration time, Solvent volumes, temperature, pH.
1.5.3. Single step and multistep extraction, Percentage extraction for single step and multistep extraction.
Separation factor.
1.5.4. Batch and continuous extraction
1.6. Chromatography : (05L)
1.6.1. Introduction to Chromatography
1.6.2. Classification of chromatographic methods based on stationary and mobile phase
1.6.3. Paper Chromatography: Principle, techniques and applications of Paper Chromatography in
separation of cations.
1.6.4. Thin layer Chromatography Principle, technique and Applications in determining the purity of a
given solute; Following progress of a given reaction.
Unit –II - Instrumental Methods-II (15 L)
2. Instruments based on the electrochemical properties of the analytes
2.1. Potentiometry: (05 L)
2.1.1. Principle.
2.1.2. Role of Reference and indicator electrodes
2.1.3. Applications in Neutralisation reactions with reference to the titration of a Strong acid against a
Strong Base (using quinhydrone electrode)
2.1.4. Graphical methods for detection of end points
2.2. pHmetry: (04 L)
2.2.1. Principle
2.2.2. Types of pH meters.
2.2.3. Principle, Construction Working and Care of Combined Glass electrode
2.2.4. Applications in Titrimetry (Strong acid-Strong Base) biological and environmental analysis.
2.3. Conductometry: (06 L)
2.3.1. Principle
2.3.2. Conductivity cell its construction and care

DEPARTMENT OF CHEMISTRY
2.3.3. Applications in Neutralisation Titrimetry with respect to
i. Strong Acid-Strong Base
ii. Strong Acid-Weak Base
iii. Strong Base-weak Acid
iv. Weak Acid- Weak Base.
2.3.4. Advantages & limitations of conductometric titrations.
Unit III- Statistical Treatment of analytical data --II (15 L)
3.1.Nature of Indeterminate Errors: (03L)
3.1.1. The true and acceptable value of a result of analysis
3.1.2. Measures of central tendency: mean, median. mode, average
3.1.3. Measures of dispersion: Absolute deviation, relative deviation, relative average deviation, standard
deviation,(s, sigma) variance, coefficient of variation.
3.2.Distribution of random errors: (02L)
3.2.1. Gaussian distribution curve.
3.2.2. Equation and salient features of Gaussian distribution curve
3.3.Concept of Confidence limits and confidence interval and its computation using (03 L)
(i) Population standard deviation
(ii) Student’s t test
(iii) Range
3.4.Criteria for rejection of doubtful result (02 L)
(i) 2.5 d rule
(ii) 4.0 d rule
(iii) Q test
3.5.Test of Significance (02 L)
(i) Null hypothesis
(ii) F-test ( variance ratio test)
3.6. Graphical representation of data and obtaining best fitting straight line (03 L)
(a) For line passing through origin
(b) For line not passing through origin [ Numerical problems wherever possible, expected ]
References:
1. Instrumental Analysis by Douglas A. Skoog, F. James Holler, Stanley R. Crouch

DEPARTMENT OF CHEMISTRY
2. Instrumental methods of analysis by Willard, H.H.; Merritt, L.L. Jr.; Dean, J.A.; Settle,7th Edition
3. Fundamental of Analytical Chemistry by Douglas A. Skoog, West, F. James Holler, S. R. Crouch
4. Modern Analytical Chemistry by David Harvey, McGraw-Hill Higher Education
5. Skoog et al. “Fundamentals of Analytical chemistry" Cengage Learning, Eight Edition, chapter 13, 14
and 15
6. Day and Underwood, “Quantitative analysis" prentice hall 1991, chapter3
7. S.M. Khopkar, “ Basic Concepts of Analytical Chemistry”, IInd Edition New Age International
Publisher
8. Gary D. Christan,” Analytical Chemistry”, VIth Edition, Wiley Students Edition, Chapter No 8,9,10
9. Fundamental of Analytical Chemistry by Douglas A. Skoog, West, F. James Holler, S. R. Crouch
10. Modern Analytical Chemistry , David Harvey ( page numbers 232 -265)
11. Instrumental Methods of Chemical Analysis by Gurdeep R. Chatwal , Sham K. Anand pp 2.107-2.148
12. Principles of Instrumental Analysis by Skoog, Holler, Nieman, 5th Edition pp 143-172.
13. Instrumental Methods of Analysis by Willard, Merritt, Dean, Settle 7th Edition pp 118-181.

DEPARTMENT OF CHEMISTRY
Semester End Theory Examinations:

Scheme of Examination
Semester End Theory Examinations:

There will be a Semester-end external theory examination of 100 marks for each of the courses
USCH401, USCH402, USCH403 of semester IV to be conducted by College.

Duration: The examinations shall be of 3 Hours duration.

1. Theory Question Paper Pattern:

a) There shall be FIVE questions. The Q.1 shall be of objective type for 20 marks based on the
entire syllabus consisting of multiple choice questions, match the following, true or false etc. The
questions Q.2, Q.3 and Q.4 shall be of 20 marks, each based on the unit I (Physical Chemistry),
unit II (Inorganic Chemistry) and Unit III (Organic Chemistry) respectively. Q.5 is based on all
the three units.
b) All the questions are compulsory. The questions Q.2, Q.3, Q.4, Q. 5 shall have internal
choices within the questions. Including the choices, the marks for each question shall be of 40.
c) The questions Q.1, Q.2, Q.3, Q.4 and Q.5 may be subdivided into sub-questions as A, B, C, D,
E & F.

Q.1 Based On Unit I, II & III

(A) Select the correct option and complete the following sentences. (any twelve) 12

(B) State whether the following statements are true or false. (any three) 03
(C) Match the column. (any five) 05

Q. 2 Attempt any four from A or A /B or B/C or C Unit I Marks 20

Q. 3 Attempt any four from A or A /B or B/C or C Unit II Marks 20
Q. Attempt any four from A or A /B or B/C or C Unit III Marks 20
Q. 5 Attempt any four from A/B/C/D/E/F Unit I, II & III Marks 20

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Chemistry Practical Based on Paper I, II & III
Program Code: 1S00144 Course Code: USCHP4, USCHP5 & USCHP6
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: S. Y. B. Sc. Semester : IV

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Understand the use potentiometer in determination of standard e.m.f. and ΔG of cell.
CO2 Determine the amount of HCl in solution potentiometrically.
CO3 Learn to prepare inorganic compounds.
CO4 Identify name and structure of unknown bifunctional solid or liquid organic compound by
performing systematic qualitative analysis.
CO5 Know the tools used in analytical chemistry.
CO6 Perform separation of metal ions in a sample by paper chromatography.
CO7 Know handling/use of conductometer and determination of end point in conductometric titration.
CO8 Estimate Fe (II) ions using potentiometer.
CO8 Acquire skill in calculation of % error during estimation.

Unit I: Physical Chemistry

1. To determine standard EMF and the standard free energy change of Daniel cell potentiometrically
2. To determine the amount of HCl in the given sample potentiometrically.
3. Compare the strengths of HCl and H2SO4 by studying kinetics of acid hydrolysis of methyl acetate.
4. Industrial visit report.
Unit II: Inorganic Chemistry
1. Inorganic preparation – Nickel dimethyl glyoxime using microscale method.
2. Complex cation – Tris (ethylene diamine) nickel (II) thiosulphate.
3. Complex anion – Sodium Hexanitrocobaltate (III) The aim of this experiment is to understand the
preparation of a soluble cation (sodium)and a large anion hexanitrocobaltate(III) and its use to precipitate

DEPARTMENT OF CHEMISTRY
a large cation (potassium)
4. Inorganic salt – Calcium or magnesium oxalate using PFHS technique.
Unit III: Organic Chemistry
Qualitative Analysis of bi-functional organic compounds on the basis of
1. Preliminary examination
2. Solubility profile
3. Detection of elements C, H, (O), N, S, X.
4. Detection of functional groups
5. Determination of physical constants (M.P/B.P)
Solid or liquid Compounds containing not more than two functional groups from among the following
classes may be given for analysis to be given: Carboxylic acids, phenol, carbohydrates, aldehydes,
ketones, ester, amides, nitro, anilides, amines, alkyl and aryl halides.
Analytical Chemistry:
1. Tools of Analytical Chemistry-II
2. Paper chromatography: Separation of cations like Fe(III), Ni(II) and Cu(II) in a sample.
3. Separation of a solute between two immiscible solvents to determine the distribution ratio nd/or
extraction efficiency. (Solutes could be as their aqueous solutions and the organic solvent ethyl acetate)
Suggested solute for the distribution study: Fe (III) in aqueous solutions.
4. Conductometric titration: Estimation of given acid by conductometric titration with strong base and
calculation of % error.
5. Estimation of Fe(II) in the given solution by titrating against K 2Cr2O7 potentiometrically and
calculation of % error.
6. Gravimetric estimation of Sulfate as BaSO4 and calculation of % error.
References:
Unit I:
1. Khosla B.D., Garg V.C. and Gulati A., Senior Practical Physical Chemistry, R. Chand and Co., New
Delhi (2011).
2. Garland C. W., Nibler J.W. and Shoemaker D.P., Experiments in Physical Chemistry, 8th Ed.,
McGraw-Hill, New York (2003).
3. Halpern A.M. and McBane G.C., Experimental Physical Chemistry, 3rd Ed., W.H. Freeman and Co.,
New York (2003).

DEPARTMENT OF CHEMISTRY
4. Athawale V.D. and Mathur P., Experimental Physical Chemistry, New Age International, New Delhi
(2001)
Unit II:
1. Practical Inorganic Chemistry by G. Marr and B. W. Rockett van Nostr and Reinhold Company (1972)
Unit III:
1. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)
2. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry: Preparation and
Quantitative Analysis, University Press (2000). Mann, F.G. & Saunders, B.C. Practical Organic
Chemistry, Pearson Education (2009)
3. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed.,
Pearson (2012)
4. Vogel, A.I., Tatchell, A.R., Furnis, B.S., Hannaford, A.J. & Smith, P.W.G., Textbook of Practical
Organic Chemistry, Prentice-Hall, 5th edition, 1996
Analytical:
1. D. A. Skoog, D. M. West, F. J. Holler, and S. R. Crouch, Analytical Chemistry: An Introduction, 7th
ed., Chapter 15, pp. 345-381.
2. A.I. Vogel. “Textbook of Quantitative Inorganic Analysis,” Longman, London (1961).
3. R.V. Dilts. “Analytical Chemistry. Methods of Separation,” van Nostrand, N.Y. (1974).
4. Some Experiments for B. Tech in Chemistry & Chemical Technology compiled by Prof. J. B.
BARUAH, Mrs. Abhilasha Mohan Baruah and Mr. Parikshit Gogoi.

DEPARTMENT OF CHEMISTRY
 : Question Paper Pattern :

Each Chemistry Practical Paper is of 50 Marks and 3 hours duration.

Maximum Marks: 50 Marks
Time: 3 Hours
Note: 1) Attempt all Questions
1. Perform given experiment and tabulate the result as per guidelines. 40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
 Detailed scheme of marking of Preparation /Estimation Experiment.

Observation 26
Reaction 02
Calculation 08
Systematic work 04
Total 40

 Detailed scheme of marking of Instrumental/Non-instrumental Physical or Analytical

Chemistry Experiment.

Technique 04 marks
Observations 12 marks
Calculation 06 marks
Graph 06 marks
Accuracy 12 marks
Total 40 marks
Organic Qualitative Analysis

Chemical Type 08
Preliminary test 12
Elements 08
Functional Group 08
Melting point 04
Confirmatory test 04
Name & Structure 04
Systematic work 02
Total 40

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Physical Chemistry
Program Code:1S00145 Course Code: USCH501
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Know the phenomenon of the interaction of light with matter in terms of the relationship with the
molecular structure.
CO2 Understand the basic information of physical aspects of UV-Visible, IR, Raman etc. spectroscopic
techniques.
CO3 Analyze results of measurements using molecular spectroscopy methods.
CO4 Calculate molecular weight of soluble solid from colligative properties.
CO5 Explain the process of osmosis and describe how it is applied industrially and in nature.
CO6 Get knowledge of how reactions are takes place at molecular level.
CO7 Classify reactions on the basis of their rates.
CO8 Identify various types of nuclear transmutation including nuclear fission, fusion and decay.
CO9 Know about nuclear structure, stable and unstable atomic nuclei, nuclear reactions and different
modes of radioactive decay and also methods for measurements of radioactivity.
CO10 Learn the phenomenon of adsorption & its importance.
CO11 Classify colloids, their properties and applications in detergent & food industry.

UNIT I 1.0 MOLECULAR SPECTROSCOPY (15L)

1.1 Rotational Spectrum: Introduction to dipole moment, polarization of a bond, bond moment,
molecular structure, .Rotational spectrum of a diatomic molecule, rigid rotor, moment of inertia, energy
levels, conditions for obtaining pure rotational spectrum, selection rule, nature of spectrum, determination

DEPARTMENT OF CHEMISTRY
of internuclear distance and isotopic shift.
1.2 Vibrational spectrum: Vibrational motion, degrees of freedom, modes of vibration, vibrational
spectrum of a diatomic molecule, simple harmonic oscillator, energy levels, zero point energy, conditions
for obtaining vibrational spectrum, selection rule, nature of spectrum.
1.3 Vibrational-Rotational spectrum of diatomic molecule: energy levels, selection rule, nature of
spectrum, P and R branch lines. Anharmonic oscillator - energy levels, selection rule, fundamental band,
overtones. Application of vibrational-rotational spectrum in determination of force constant and its
significance. Infrared spectra of simple molecules like H2O and CO2.
1.4 Raman Spectroscopy : Scattering of electromagnetic radiation, Rayleigh scattering, Raman
scattering, nature of Raman spectrum, Stoke’s lines, anti-Stoke’s lines, Raman shift, quantum theory of
Raman spectrum, comparative study of IR and Raman spectra, rule of mutual exclusion- CO2 molecule.
Unit 2: CHEMICAL THERMODYNAMICS (10 L)
2.1.1Colligative properties: Vapour pressure and relative lowering of vapour pressure. Measurement of
lowering of vapour pressure - Static and Dynamic method.
2.1.2 Solutions of Solid in Liquid: 2.1.2.1 Elevation in boiling point of a solution, thermodynamic
derivation relating elevation in boiling point of the solution and molar mass of non-volatile solute.
2.1.2.2 Depression in freezing point of a solution, thermodynamic derivation relating the depression in the
freezing point of a solution and the molar mass of the non-volatile solute. Beckmann Method and Rast
Method.
2.1.3 Osmotic Pressure: Introduction, thermodynamic derivation of Van't Hoff equation, Van't Hoff
Factor. Measurement of Osmotic Pressure - Berkeley and Hartley's Method, Reverse Osmosis.
2.2 CHEMICAL KINETICS (5 L)
2.2.1 Collision theory of reaction rates: Application of collision theory to 1. Unimolecular reaction
Lindemann theory and 2. Bimolecular reaction. (derivation expected for both)
2.2.2 Classification of reactions as slow, fast and ultra -fast. Study of kinetics of fast reactions by Stop
flow method and Flash photolysis (No derivation expected).
Unit 3: NUCLEAR CHEMISTRY (15L)
3.1. Introduction: Basic terms-radioactive constants (decay constant, half -life and average life) and units
of radioactivity.
3.2 Detection and Measurement of Radioactivity: Types and characteristics of nuclear radiations,
behaviour of ion pairs in electric field, detection and measurement of nuclear radiations using G. M.

DEPARTMENT OF CHEMISTRY
Counter and Scintillation Counter.
3.3 Application of use of radioisotopes as Tracers: chemical reaction mechanism, age determination -
dating by C14.
3.4 Nuclear reactions: nuclear transmutation (one example for each projectile), artificial radioactivity, Q -
value of nuclear reaction, threshold energy.
3.5 Fission Process: Fissile and fertile material, nuclear fission, chain reaction, factor controlling fission
process. multiplication factor and critical size or mass of fissionable material, nuclear power reactor and
breeder reactor.
3.6 Fusion Process: Thermonuclear reactions occurring on stellar bodies and earth.
UNIT 4: 4.1 SURFACE CHEMISTRY (6L)
4.1.1 Adsorption: Physical and Chemical Adsorption, types of adsorption isotherms. Langmuir’s
adsorption isotherm (Postulates and derivation expected). B.E.T. equation for multilayer adsorption,
(derivation not expected). Determination of surface area of an adsorbent using B.E.T. equation.
4.2 COLLOIDAL STATE 9L
4.2.1 Introduction to colloids - Emulsions, Gels and Sols
4.2.2 Electrical Properties: Origin of charges on colloidal particles, Concept of electrical double layer,
zeta potential, Helmholtz and Stern model. Electro-kinetic phenomena - Electrophoresis, Electro-osmosis,
Streaming potential, Sedimentation potential; Donnan Membrane Equilibrium.
4.2.3 Colloidal electrolytes : Introduction, micelle formation,
4.2.4 Surfactants: Classification and applications of surfactants in detergents and food industry.
References:
1. Physical Chemistry, Ira Levine, 5th Edition, 2002 Tata McGraw Hill Publishing Co. Ltd.
2. Physical Chemistry, P.C. Rakshit, 6th Edition, 2001, Sarat Book Distributors, Kolkota.
3. Physical Chemistry, R.J. Silbey, & R.A. Alberty, 3rd edition , John Wiley & Sons, Inc [part 1]
4. Physical Chemistry, G. Castellan, 3rd edition, 5th Reprint, 1995 Narosa Publishing House.
5. Modern Electrochemistry, J.O.M Bockris & A.K.N. Reddy, Maria Gamboa – Aldeco 2nd Edition, 1st
Indian reprint,2006 Springer
6. Fundamental of Molecular Spectroscopy, 4th Edn., Colin N Banwell and Elaine M McCash Tata
McGraw Hill Publishing Co. Ltd. New Delhi, 2008.
7. Physical Chemistry, G.M. Barrow, 6th Edition, Tata McGraw Hill Publishing Co. Ltd. New Delhi.
8. The Elements of Physical Chemistry, P.W. Atkins, 2nd Edition, Oxford Universtity Press Oxford.

DEPARTMENT OF CHEMISTRY
9. Physical Chemistry, G.K. Vemullapallie, 1997, Prentice Hall of India, Pvt. Ltd. New Delhi.
10. Principles of Physical Chemistry B.R. Puri, L.R. Sharma, M.S. Pathania, VISHAL PUBLISHING
Company, 2008.
11. Textbook of Polymer Science, Fred W Bilmeyer, John Wiley & Sons (Asia) Ple. Ltd., Singapore,
2007.
12. Polymer Science, V.R. Gowariker, N.V. Viswanathan, Jayadev Sreedhar, New Age International (P)
Ltd., Publishers, 2005.
13. Essentials of Nuclear Chemistry, Arnikar, Hari Jeevan , New Age International (P) Ltd., Publishers,
2011..
14. Chemical Kinetics, K. Laidler, Pearson Education India, 1987.

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Inorganic Chemistry
Program Code: 1S00145 Course Code: USCH502
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Upon completion of this course the students will be able to:

CO1 Explains many important properties of transition-metal complexes, including their colors, magnetism,
structures, stability, and reactivity.
CO2 Know the splitting pattern of d orbitals in octahedral crystal field.
CO3 Identify the strong and weak field ligands.
CO4 Evaluate the extent of splitting in octahedral complexes.
CO5 Explain the formation of coordinate compounds by using Molecular Orbital Theory.
CO6 Learn thermodynamics and kinetics of metal complex formation.
CO7 Understand the origin of electronic spectra & types of electronic transitions
CO8 Calculate number of microstates
CO9 Determine the Terms for p2 and d1 electronic configurations.
CO10 Know how to prepare organometallic compounds and their use in chemical reactions.
CO11 Write the general characteristics, properties and uses of noble gases.
CO12 Understand the role of metal ions in biological systems.

Unit I: Molecular Symmetry and Chemical Bonding

1.1Molecular Symmetry (6L)
1.1.1 Introduction and Importance of Symmetry in Chemistry.
1.1.2 Symmetry elements and Symmetry operations.
1.1.3 Concept of a Point Group with illustrations using the following point groups :(i)CϖV (ii) Dϖh (iii) C2V
(iv) C3v (v) C2h and (vi) D3h
1.2 Molecular Orbital Theory for heteronuclear diatomic molecules and polyatomic species (9L)
1.2.1 Comparison between homonuclear and heteronuclear diatomic molecules.
1.2.2. Heteronuclear diatomic molecules like CO, NO and HCl, appreciation of modified MO diagram for

DEPARTMENT OF CHEMISTRY
CO.
1.2.3 Molecular orbital theory for H3 and H3 + (correlation diagram expected).
1.2.4. Molecular shape to molecular orbital approach in AB2 molecules. Application of symmetry
concepts for linear and angular species considering σ- bonding only. (Examples like: i) BeH2, ii) H2O).
UNIT-II SOLID STATE CHEMISTRY
2.1 Structures of Solids (11L)
2.2.1 Explanation of terms viz. crystal lattice, lattice point, unit cell and lattice constants.
2.1.2 Closest packing of rigid spheres (hcp, ccp), packing density in simple cubic, bcc and fcc lattices.
Relationship between density, radius of unit cell and lattice parameters.
2.1.3 Stoichiometric Point defects in solids (discussion on Frenkel and Schottky defects expected).
2.2 Superconductivity (4L )
2.2.1 Discovery of superconductivity.
2.2.2 Explanation of terms like superconductivity, transition temperature, Meissner effect.
2.2.3 Different types of super conductors viz. conventional superconductors, alkali metal fullerides, high
temperature super conductors.
2.2.4 Brief application of superconductors.
UNIT-III: CHEMISTRY OF INNER TRANSITION ELEMENTS (15L)
3.1 Introduction: Position in periodic table and electronic configuration of lanthanides and actinides.
3.2 Chemistry of Lanthanides with reference to (i) lanthanide contraction and its consequences(ii)
Oxidation states (iii) Ability to form complexes (iv) Magnetic and spectral properties
3.3 :Occurrence, extraction and separation of lanthanides by (i) Ion Exchange method and (ii) Solvent
extraction method (Principles and technique)
3.4 Applications of lanthanides
UNIT-IV: SOME SELECTED TOPICS
4.1 Chemistry of Non-aqueous Solvents (5 L)
4.1.1Classification of solvents and importance of non-aqueous solvents.
4.1.2 Characteristics and study of liquid ammonia, dinitrogen tetra oxide as non-aqueous solvents with
respect to: (i) acid-base reactions and (ii) redox reactions.
4.2 Comparative Chemistry of Group 16 (5L)
4.2.1 Electronic configurations, trends in physical properties, allotropy
4.2.2 Manufacture of sulphuric acid by Contact process.

DEPARTMENT OF CHEMISTRY
4.3 Comparative Chemistry of Group 17 (5L)
4.3.1 Electronic configuration , General characteristics, anomalous properties of fluorine, comparative
study of acidity of oxyacids of chlorine w.r.t acidity, oxidising properties and structures(on the basis of
VSEPR theory)
4.3.2 Chemistry of interhalogens with reference to preparations, properties and structures (on the basis of
VSEPR theory)
References:
Unit-I
1. Per Jensen and Philip R. Bunker , Fundamentals of Molecular Symmetry , Series in Chemical Physics,
Taylor & Francis Group
2. J. S. Ogden, Introduction to Molecular Symmetry, Oxford University Press
3. Derek W. Smith, Molecular orbital theory in inorganic chemistry Publisher: Cambridge University
Press
4. C. J. Ballhausen, Carl Johan Ballhausen, Harry B. Gray Molecular Orbital Theory: An Introductory
Lecture Note and Reprint Volume Frontiers in chemistry Publisher W.A. Benjamin, 1965
5. Jack Barrett and Mounir A Malati, Fundamentals of Inorganic Chemistry, Affiliated East west Press
Pvt. Ltd., New Delhi.
6. Satya Prakash, G. D. Tuli, R.D. Madan, Advanced Inorganic Chemistry. S. Chand & Co Ltd
Unit-II
1. Lesley E. Smart, Elaine A. Moore Solid State Chemistry: An Introduction, 2nd Edition CRC Press,
2. C. N. R. Rao Advances in Solid State Chemistry
3. R.G. Sharma Superconductivity: Basics and Applications to Magnets
4. Michael Tinkham ,Introduction to Superconductivity: Vol I (Dover Books on Physics)
5. R. Gopalan, Inorganic Chemistry for Undergraduates, Universities Press India.
6. Richard Harwood, Chemistry, Cambridge University Press,
7. Satya Prakash, G. D. Tuli, R.D. Madan, Advanced Inorganic Chemistry. S. Chand & Co Ltd.
Unit-III
1. Cotton, Wilkinson, Murillo and Bochmann, Advanced Inorganic Chemistry, 6th Edition.
2. Greenwood, N.N. and Earnshaw, Chemistry of the Elements, Butterworth Heinemann. 1997.
3. Huheey, J.E., Inorganic Chemistry, Prentice Hall, 1993.
4. G. Singh, Chemistry of Lanthanides and Actinides, Discovery Publishing House

DEPARTMENT OF CHEMISTRY
5. Simon Cotton , Lanthanide and Actinide Chemistry Publisher: Wiley-Blackwell
Unit-IV
1. B. H. Mahan, University Chemistry, Narosa publishing.
2. R. Gopalan, Inorganic Chemistry for Undergraduates, Universities Press India.
3. J. D. Lee, Concise Inorganic Chemistry, 4th Edn., ELBS,
4. D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press
5. Cotton, Wilkinson, Murillo and Bochmann, Advanced Inorganic Chemistry, 6th Edition.
6. Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt, Ltd. (2002).
7. Richard Harwood, Chemistry, chapter 10 Industrial inorganic chemistry
8. Greenwood, N.N. and Earnshaw, Chemistry of the Elements, Butterworth Heinemann. 1997.
9. Huheey, J.E., Inorganic Chemistry, Prentice Hall, 1993
10. Satya Prakash, G. D. Tuli, R.D. Madan, Advanced Inorganic Chemistry. S. Chand & Co Ltd 2004

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Organic Chemistry
Program Code: 1S00145 Course Code: USCH503
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcome:
Upon completion of this course the students will be able to:
CO1 Predict the mechanisms of organic reactions and the species involved in it.
CO2 Understand the various types of pericyclic reactions.
CO3 Illustrate photocatalyzed reactions.
CO4 Learn how to find chiral compounds (biphenyls & allenes) without chiral centre.
CO5 Know the need of agrochemicals, their advantages & disadvantages.
CO6 Learn preparation methods and reactivity pattern of pyridine-N-oxide, quinoline and iso-quionoline.
CO7 Write IUPAC name of cyclic compounds from structure & vice versa.
CO8 Design synthesis of nitroanilines, alcohols, alkanes & halobenzoic acids.
CO9 Understand importance & principles of green chemistry and its applications in synthesis of organic
molecules.
CO10 determine the conjugation & fragmentation pattern of organic molecules using UV-visible & Mass
spectroscopy.
CO11 Learn isolation, structure determination and synthesis of natural products (Citral, Nicotine &
Adrenaline)

Unit I
1.1 Mechanism of organic reactions (10 L)
1.1.1 The basic terms & concepts: bond fission, reaction intermediates, electrophiles & nucleophiles,
ligand, base, electrophilicity vs. acidity & nucleophilicity vs basicity.
1.1.2 Neighbouring group participation in nucleophilic substitution reactions: participation of lone pair of
electrons, kinetics and stereochemical outcome.

DEPARTMENT OF CHEMISTRY
1.1.3 Acyl nucleophilic substitution (Tetrahedral mechanism): Acid catalyzed esterification of carboxylic
acids (AAC2) and base promoted hydrolysis of esters ( BAC2).
1.1.4 Pericyclic reactions, classification and nomenclature
1.1.4.1 Electro cyclic reactions (ring opening and ring closing), cycloaddition, sigma tropic
Rearrangement, group transfer reactions, cheletropic reaction (definition and one example of each type)
1.1.4.2 Pyrolytic elimination: Cope, Chugaev, pyrolysis of acetates
1.2 Photochemistry (5 L)
1.2.1 Introduction: Difference between thermal and photochemical reactions. Jablonski diagram,
singlet and triplet states, allowed and forbidden transitions, fate of excited molecules, photosensitization.
1.2.2 Photochemical reactions of olefins: photoisomerization, photochemical rearrangement of 1,4-
dienes (di- π methane)
1.2.3 Photochemistry of carbonyl compounds: Norrish I, Norrish II cleavages. Photo reduction (e.g.
benzophenone to benzpinacol)
Unit II:
2.1 Stereochemistry I (5 L)
2.1.1 Molecular chirality and elements of symmetry: Mirror plane symmetry, inversion center, roation -
reflection (alternating) axis.
2.1.2 Chirality of compounds without a stereo genic center: cummulenes and biphenyls.
2.2 Agrochemicals (4 L)
2.2.1 General introduction & scope, meaning & examples of insecticides, herbicides, fungicide,
rodenticide, pesticides, plant growth regulators.
2.2.2 Advantages & disadvantages of agrochemicals
2.2.3 Synthesis & application of IAA ( Indole Acetic Acid) & Endosulphan,
2.2.4 Bio pesticides – Neem oil & Karanj oil.
2.3 Heterocyclic chemistry: (6 L)
2.3.1 Reactivity of pyridine-N-oxide, quinoline and iso-quionoline.
2.3.2 Preparation of pyridine-N-oxide, quinoline (Skraup synthesis) and iso-quinoline (Bischler-
Napieralski synthesis).
2.3.3 Reactions of pyridine-N-oxide: halogenation, nitration and reaction with NaNH2/liq.NH3, n-BuLi.
2.3.4 Reactions of quinoline and isoquinoline; oxidation, reduction, nitration, halogenation and reaction
with NaNH2/liq.NH3, n-BuLi.

DEPARTMENT OF CHEMISTRY
Unit III:
3.1 IUPAC (5 L)
IUPAC Systematic nomenclature of the following classes of compounds (including compounds upto
two substituents / functional groups):
3.1.1 Bicyclic compounds – spiro, fused and bridged (upto 11 carbon atoms) – saturated and unsaturated
compounds.
3.1.2 Biphenyls
3.1.3 Cummulenes with up to 3 double bonds
3.1.4 Quinolines and Isoquinolines
3.2 Synthesis of organic compounds (10L)
3.2.1 Introduction: Linear and convergent synthesis, criteria for an ideal synthesis, concept of chemo
selectivity and regioselectivity with examples, calculation of yields.
3.2.2 Multicomponent Synthesis: Mannich reaction and Biginelli reaction. Synthesis with examples (no
mechanism)
3.2.3 Green chemistry and synthesis:
Introduction: Twelve principles of green chemistry, concept of atom economy and E-factor, calculations
and their significance, numerical examples.
i) Green reagents: dimethyl carbonate.
ii) Green starting materials : D-glucose
iii) Green solvents : supercritical CO2
iv) Green catalysts: Bio catalysts.
3.2.4 Planning of organic synthesis
i) Synthesis of nitroanilines. (o & p)
ii) synthesis of halobenzoic acid.(o & p)
iii) Alcohols (primary / secondary / tertiary) using Grignard reagents.
iv) Alkanes (using organo lithium compounds)
Unit 4:
4.1 Spectroscopy I (5 L)
4.1.1 Introduction: Electromagnetic spectrum, units of wavelength and frequency
4.1.2 UV – Visible spectroscopy: Basic theory, solvents, nature of UV-Visible spectrum, concept of
chromophore, auxochrome, bathochromic and hypsochromic shifts, hyperchromic and hypochromic

DEPARTMENT OF CHEMISTRY
effects, chromophore-chromophore and chromophore-auxochrome interactions.
4.1.3 Mass spectrometry: Basic theory. Nature of mass spectrum. General rules of fragmentation.
Importance of molecular ion peak, isotopic peaks, base peak, nitrogen rule, rule of 13 for determination of
empirical formula and molecular formula. Fragmentation of alkanes and aliphatic carbonyl compounds.
4.2 Natural Products: (10L)
4.2.1. Terpenoids: Introduction, Isoprene rule, special isoprene rule and the gem-dialkyl rule.
4.2.2 Citral:
a) Structural determination of citral.
b) Synthesis of citral from methyl heptenone
c) Isomerism in citral. (cis and trans form).
4.2.3. Alkaloids Introduction and occurrence.
Hofmann’s exhaustive methylation and degradation in: simple open chain and N – substituted monocyclic
amines.
4.2.4 Nicotine:
a) Structural determination of nicotine. (Pinner’s work included )
b) Synthesis of nicotine from nicotinic acid
c) Harmful effects of nicotine.
4.2.5 Hormones:
Introduction, structure of adrenaline (epinephrine), physiological action of adrenaline. Synthesis of
adrenaline from
a) Catechol
b) p-hydroxybenzaldehyde ( Ott’s synthesis)
References:
Unit I
1. A guidebook to mechanism in Organic Chemistry, 6th edition, Peter Sykes, Pearson education, New
Delhi
2. Organic Reaction Mechanism, 4th edition, V. K. Ahluwalia, R. K. Parashar, Narosa Publication.
3. Organic reactions & their mechanisms,3rd revised edition, P.S. Kalsi, New Age International
Publishers.
4. M. B. Smith and J. March, Advanced organic chemistry- reactions mechanism and structure, 5th
edition.

DEPARTMENT OF CHEMISTRY
5. Organic Chemistry, 7th Edition, R.T. Morrison, R. N. Boyd & S. K. Bhattacharjee, Pearson.
6. Organic chemistry,8th edition, John Mc Murry
Unit II
1. L. Eliel , stereochemistry of carbon compounds, Tata McGraw Hill
2. Stereochemistry P. S. Kalsi , New Age International Ltd.,4th Edition
3. Stereochemistry by Nassipuri.
4. Insecticides & pesticides: Saxena A. B., Anmol publication.
5. Growth regulators in Agriculture & Horticulture: Amarjit Basra, CRC press 2000.
6. Agrochemicals and pesticides: A. Jadhav and T. V. Sathe.
7. Name Reactions in Heterocyclic Chemistry, Jie-Jack Li, Wiley-Interscience publications, 2005.
8. Handbook of Heterocyclic Chemistry, 2nd Edition, Alan R. Katritzky and Alexander F. Pozharskii,
Elsevier Science Ltd, 2000.
9. Heterocyclic Chemistry, 5th Edition, John A. Joule and Keith Mills, Wiley publication, 2010.
10. Heterocyclic chemistry, 3rd Edition, Thomas L. Gilchrist, Pearson Education, 2007
Unit III
1. Nomenclature of Organic Chemistry: IUPAC recommendations and preferred Names 2013, RSC
publication.
2. IUPAC nomenclature by S. C. Pal.
3. Green chemistry an introductory text: Mike Lancaster.
4. Green chemistry: V. K. Ahluwalia (Narosa publishing house pvt. ltd.)
5. Green chemistry an introductory text: RSC publishing.
6. New trends in green chemistry V. K. Ahluwalia , M. Kidwai, Klumer Academic publisher
7. Green chemistry by V. Kumar.
8. Organic chemistry: Francis Carey
9. Organic chemistry: Carey and Sundberg.
Unit IV
1. Organic spectroscopy (Second edition),Jag Mohan , Narosa publication
2. Spectroscopy, Pavia, Lampman, Kriz, Vyvyan.
3. Elementary organic spectroscopy (Third edition), Y. R. Sharma, S. Chand publication.
4. Introduction to spectroscopy (third edition), Pavia, Lampman, Kriz, john vondeling, Emily Barrosse.
5. Organic chemistry Paula Y. Bruice, Pearson education.

DEPARTMENT OF CHEMISTRY
6. Spectral identification of organic molecules by Silverstein.
7. Absorption spectroscopy of organic molecules by V. M. Parikh
8. Chemistry of natural products by Chatwal Anand – Vol I and Vol II
9. Chemistry of natural products by O.P. Agarwal
10. Chemistry of natural products by Meenakshi Sivakumar and Sujata Bhat.
11. Organic chemistry by Morrision and Boyd, 7th edition.
12. I. L. Finar, Vol-I and Vol-II, 5th edition.

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Analytical Chemistry
Program Code: 1S00145 Course Code: USCH504
(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Know the importance of quality control and quality assurance in chemical industry.
CO2 Perform interconversion between concentration units.
CO3 Learn scientific sampling process for solid, liquid & gaseous material.
CO4 Understand theoretical aspects of types of chemical titrations.
CO5 Understand principles, instrumentation, experimental design, and data analysis of AAS & FES.
CO6 acquainted with use of various spectroscopic techniques for measurements.
CO7 Know about modern and sophisticated separation techniques.

Unit I: INTRODUCTION TO QUALITY CONCEPTS,CHEMICAL CALCULATIONS AND

SAMPLING
1.1 Quality in Analytical Chemistry (05 L)
1.1.1 Concepts of Quality, Quality Control and Quality Assurance
1.1.2 Importance of Quality concepts in Industry
1.1.3 Chemical Standards and Certified Reference Materials; Importance in chemical analysis. Quality of
material: Various grades of laboratory reagents.
1.2 Chemical Calculations (Numericals and word problems are expected) 04 L
1.2.1 Inter conversion of various concentration units. (Conversion of concentration from one unit to
another unit with examples)
1.2.2 Percent composition of elements in chemical compounds.
1.3 Sampling (06 L)

DEPARTMENT OF CHEMISTRY
1.3.1 Purpose, significance and difficulties encountered in sampling
1.3.2 Sampling of solids: Sample size – bulk ratio, size to weight ratio, multistage and sequential
sampling, size reduction methods, sampling of compact solids, equipments and methods of sampling of
compact solids, sampling of particulate solids, methods and equipments used for sampling of particulate
solids.
1.3.3 Sampling of liquids: Homogeneous and heterogeneous, Static and flowing liquids.
1.3.4 Sampling of gases: Ambient and stack sampling: Apparatus and methods for sampling of gases.
1.3.5 Collection, preservation and dissolution of the sample.
Unit II: CLASSICAL METHODS OF ANALYSIS (TITRIMETRY)
2.1 Redox Titrations (Numerical and word Problems are expected) (08 L)
2.1.1 Introduction
2.1.2 Construction of the titration curves and calculation of Esystem in aqueous medium in case of:
(1) One electron system
(2) Multielectron system
2.1.3 Theory of redox indicators, Criteria for selection of an indicator Use of diphenyl amine and ferroin
as redox indicators
2.2 Complexometric Titrations (07 L)
2.2.1 Introduction, construction of titration curve
2.2.2 Use of EDTA as titrant and its standardisation, absolute and conditional formation constants of
metal EDTA complexes, Selectivity of EDTA as a titrant. Factors enhancing selectivity with examples.
Advantages and limitations of EDTA as a titrant.
2.2.3 Types of EDTA titrations.
2.2.4 Metallochromic indicators, theory, examples and applications
Unit III: OPTICAL METHODS
3.1 Atomic Spectroscopy: Flame Emission spectroscopy(FES) and Atomic Absorption Spectroscopy
(AAS) (07 L)
3.1.1 Introduction, Energy level diagrams, Atomic spectra, Absorption and Emission Spectra
3.1.2 Flame Photometry – Principle, Instrumentation (Flame atomizers, types of Burners, Wavelength
selectors, Detectors)
3.1.3 Atomic Absorption Spectroscopy – Principle, Instrumentation (Source, Chopper, Flame and
Electrothermal Atomiser )

DEPARTMENT OF CHEMISTRY
3.1.4 Quantification methods of FES and AAS – Calibration curve method, Standard addition method and
Internal standard method.
3.1.5 Comparison between FES and AAS.
3.1.6 Applications, Advantages and Limitations.
3.2 Molecular Fluorescence and Phosphorescence Spectroscopy (04 L)
3.2.1 Introduction and Principle
3.2.2 Relationship of Fluorescence intensity with concentration
3.2.3 Factors affecting Fluorescence and Phosphorescence
3.2.4 Instrumentation and applications
3.2.5 Comparison of Fluorimetry and Phosphorimetry
3.2.6 Comparison with Absorption methods
3.3 Turbidimetry and Nephelometry (04 L)
3.3.1 Introduction and Principle
3.3.2 Factors affecting scattering of Radiation: Concentration, particle size, wavelength, refractive index
3.3.3 Instrumentation and Applications
Unit IV: METHODS OF SEPARATION – I
4.1 Solvent Extraction (6 L)
4.1.1 Factors affecting extraction: Chelation, Ion pair formation and Solvation
4.1.2 Graph of percent extraction versus pH. Concept of [pH]1/2 and its significance (derivation not
expected)
4.1.3 Craig’s counter current extraction: Principle, apparatus and applications.
4.1.4 Solid phase extraction: Principle, process and applications with special reference to water and
industrial effluent analysis.
4.1.5 Comparison of solid phase extraction and solvent extraction.
4.2 High Performance Liquid chromatography (HPLC) (6 L)
4.2.1 Introduction and Principle Instrumentation- components with their significance: Solvent Reservoir,
Degassing system, Pumps-(reciprocating pumps, screw driven- syringe type pumps, pneumatic pumps,
advantages and disadvantages of each pump), Precolumn, Sample injection system, HPLC Columns,
Detectors(UV –Visible detector, Refractive index detector)
4.2.2 Qualitative and Quantitative Applications of HPLC
4.3 High Performance Thin Layer Chromatography (HPTLC) (3 L)

DEPARTMENT OF CHEMISTRY
4.3.1 Introduction and Principle Stationary phase, Sample application and mobile phase
4.3.2 Detectors
a) Scanning densitometer- Components. Types of densitometer- Single beam and Double beam
b) Fluorometric Detector
4.3.3 Advantages, disadvantages and applications
4.3.4 Comparison of TLC and HPTLC
References:
1. 3000 solved problems in Chemistry, David E. Goldberg, PhD., Schaums Outline Unit/s: (1.2)
2. A guide to Quality in Analytical Chemistry: An aid to accreditation, CITAC and EURACHEM, (2002),
Unit/s (1.1)
3. A premier sampling solids, liquids and gases, Smith Patricia I, American statistical association and the
society for industrial and applied mathematics, (2001) Unit/s (1.3)
4. Analytical Chemistry, Gary. D Christan, 5th edition Unit/s (4.1,4.2,4.3)
5. Analytical Chemistry Skoog, West ,Holler,7th Edition: Unit/s (2.1)
6. Analytical Chromatography, Gurdeep R Chatwal, Himalaya publication Unit/s (4.1,4.2,4.3)
7. Basic Concepts of Analytical Chemistry, by S M Khopkar, new Age International (p) Limited Unit/s
(4.1,4.2,4.3)
8. Chemical methods of separation, J A Dean, Van Nostrand Reinhold, 1969 Unit/s (4.1,4.2,4.3)
9. Fundamentals of Analytical Chemistry by Skoog and West , 8th Edition Unit/s (4.1,4.2,4.3)
10. Handbook of quality assurance for the analytical chemistry laboratory, 2ndEdn., James P. Dux Van
Nostr and Reinhold, 1990 Unit/s (1.1)
11. High Performance Thin Layer Chromatography by Dr P.D. Sethi, CBS Publisher and Distribution
Unit/s (4.1,4.2,4.3)
12. High Performance Thin Layer Chromatography in Food analysis, by Prem kumar, CBS Publisher and
distributer Unit/s (4.1,4.2,4.3)
13. Instrumental methods of Analysis, by Dr Supriya S Mahajan, Popular Prakashan Ltd Unit/s
(4.1,4.2,4.3)
14. Instrumental methods Of Analysis, by Willard Merritt Dean, 7thEdition, CBS Publisher and
distribution Pvt Ltd Unit/s (3.1,3.2,3.3)
15. Instrumental Methods of Chemical Analysis by B.K. Sharma Goel Publishing House Unit/s
(4.1,4.2,4.3)

DEPARTMENT OF CHEMISTRY
16. Principles of Instrumental Analysis , 5th Edition, By Skoog, Holler, Nieman Unit/s
(4.1,4.2,4.3)(3.1,3.2,3.3)
17. Quality control and Quality assurance in Analytical Chemical Laboratory, Piotr Konieczka and Jacek
Namiesnik, CRC press (2018) Unit/s (1.1)
18. Quality in the Analytical Chemistry Laboratory, Elizabeth Prichard, Neil T. Crosby, Florence
Elizabeth Prichard, John Wiley and Sons, 1995 Unit/s (1.1)
19. Solvent extraction and ion exchange, J Marcus and A. S. Kertes Wiley INC 1969 Unit/s (4.1,4.2,4.3)
20. Thin Layer Chromatography, A LAB. Handbook, Egon Stahl, Springer International Student Edition
Unit/s (4.1,4.2,4.3)

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Applied Component: Drugs & Dyes
Program Code: 1S00145 Course Code: USACDD501

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcome:
Upon completion of this course the students will be able to:
CO1 familiar with the basic terms used in drug chemistry.
CO2 Know the formulation technique & ways of drug administration.
CO3 Learn the classification of drug molecules on the basis of pharmacological actions.
CO4 Outline the synthesis and mode of action of various kinds of drug molecules.
CO5 Aware with the dyestuff industry.
CO6 Identify natural and synthetic dyes.
CO7 Outline the raw material required for the preparation of dyes.
CO8 Illustrate the types of fibres.
CO9 Classify dyes based on dyeing method and applicability on substrate.
CO10 Know the factors affecting on colour.
CO11 Write the unit processes and intermediates used in the dye industry.

Unit I:
1.1 General Introduction to Drugs (8L)
1.1.1 Definition of a drug, sources of drugs, requirements of an ideal drug, classification of drugs (based
on therapeutic action),
1.1.2 Nomenclature of drugs: Generic name, Brand name, Systematic name
1.1.3 Definition of the following medicinal terms: Pharmacon, Pharmacology, Pharmacophore, Prodrug,
Half – life efficiency, LD50, ED50, GI50 Therapeutic Index.

DEPARTMENT OF CHEMISTRY
1.1.4 Brief idea of the following terms: Receptors, Agonists, Antagonists, Drug-receptor interaction, Drug
Potency, Bioavailability, Drug toxicity, Drug addiction, Spurious Drugs, Misbranded Drugs,
Adulterated Drugs, Pharmacopoeia.
1.2 Routes of Drug Administration and Dosage Forms (3L)
1.2.1 Oral and Parenteral routes with advantages and disadvantages.
1.2.2 Formulations & combination formulation, Different dosage forms (including Patches & Adhesives,
emphasis on sustained release formulations and enteric coated tablets).
1.3 Pharmacodynamic agents: A brief introduction of the following pharmacodynamic agents and the
study with respect to their chemical structure, chemical class, therapeutic uses, and side effects.
1.3.1 CNS Drugs: (4 L)
Classification based on pharmacological actions: CNS Depressants & CNS Stimulants. Concept of
sedation and hypnosis, anaesthesia.

(Oxazolidinediones) (Synthesis from acetone)

UNIT-II (Drugs)
2.1 Analgesics, Antipyretics and Anti-inflammatory Drugs. (4L)
2.1.1 Analgesics and Antipyretics

-Amino phenols)
2.1.2 Anti-inflammatory Drugs
Mechanism of inflammation and various inflammatory conditions.

- Aryl anthranilic
acids) (Synthesis from 2,6-dichlorodiphenyl amine)
2.2 Antihistaminic Drugs (2L)

DEPARTMENT OF CHEMISTRY
 hydramine (Ethanol amines)
-Chlorobenzhydryl chloride)

2.3 Cardiovascular drugs (3L)

Classification based on pharmacological action
Isosorbide dinitrate (Nitrates)

-Hydroxy phenyl acetamide)

rimidine)
2.4 Antidiabetic Agents (2L)
General idea and types of diabetes; Insulin therapy

-(5-ethylpyridin-2-yl) ethanol)
2.5 Antiparkinsonism Drugs (2L)
Idea of Parkinson’s disease.

2.6 Drugs for Respiratory System (2L)

General idea of: Expectorants; Mucolytes; Bronchodilators; Decongestants; Antitussives

Codeine Phosphate (Opiates)

Unit III: (Dyes)
3.1 Introduction to the dye-stuff Industry (5L)

DEPARTMENT OF CHEMISTRY
3.1.1 Dyes
Definition of dyes, requirements of a good dye i.e. Colour, Chromophore and Auxochrome, Solubility,
Linearity, Coplanarity, Fastness, Substantivity, Economic viability. Definition of fastness and its
properties and Mordants with examples. Explanation of nomenclature or abbreviations of commercial
dyes with at least one example suffixes – G, O, R, B, K, L, C, S H, 6B, GK, 6GK, Naming of dyes by
colour index (two examples) used in dye industries.
3.1.2 Natural and Synthetic Dyes
Natural Dyes: Definition and limitations of natural dyes. Examples and uses of natural dyes w.r.t Heena,
Turmeric, Saffron, Indigo, Madder, Chlorophyll –names of the chief dyeing material/s in each natural dye
[structures not expected], Synthetic dyes: Definition of synthetic dyes, primaries and intermediates.
Important milestones in the development of synthetic dyes – Emphasis on Name of the Scientist, dyes and
the year of the discovery is required. (Structure is not expected).
3.2 Substrates for Dyes : Types of fibres (3L)
3.2.1 Natural: cellulosic and proteinaceous fibres, examples – wool, silk and cotton structures and names
of dyes applied on each of them.
3.2.2 Semi – synthetic: definition and examples [structures not expected]
3.2.3 Synthetic: Nylon, Polyesters and Polyamides structures and names of dyes applied on each of them
3.2.4 Blended fabrics: definition and examples [structures not expected]
3.2.5 Binding forces of dyes on substrate: ionic forces, covalent linkages, hydrogen bonding, vander-walls
forces
3.3 Classification of dyes based on applications and dyeing methods (7L)
3.3.1 Dyeing methods Basic Operations involved in dyeing process:
i. Preparation of fibres ii. Preparation of dyebath
iii. Application of dyes iv. Finishing
Dyeing Method of Cotton Fibres: (i) Direct dyeing (ii) Vat dyeing
(iii) Mordant dyeing (iv) Disperse dyeing
3.3.2 Classification of dyes based on applicability on substrates (examples with structures)
(a) Acid Dyes- Orange II,
(b) Basic Dyes-methyl violet,
(c) Direct cotton Dyes- Benzofast Yellow 5GL
(d) Azoic Dyes – Diazo components; Fast yellow G, Fast orange R.

DEPARTMENT OF CHEMISTRY
Coupling components. Naphthol AS, Naphthol ASG
(e) Mordant Dyes-Eriochrome Black A, Alizarin.
(f) Vat Dyes- Indanthrene brown RRD,
(g) Sulphur Dyes- Sulphur Black T (no structure)
(h) Disperse Dyes-Celliton Fast brown 3R,
(i) Reactive Dyes- Cibacron Brilliant Red B,
3.3.3 Optical Brighteners: General idea, important characteristics of optical brighteners and their classes
[Stilbene, Coumarin, Heterocyclic vinylene derivatives, Diaryl pyrazolines, Naphthylamide derivatives]
general structure of each class.
Unit – IV (Dyes)
4.1 Colour and Chemical Constitution of Dyes (4L)
4.1.1 Absorption of visible light, Colour of wavelength absorbed, Complementary colour.
4.1.2 Relation between colour and chemical constitution.
(i) Armstrong theory (quinonoid theory) and its limitations.
(ii) Witt’s Theory: Chromophore, Auxochrome, Bathochromic & Hypsochromic Shift, Hypochromic &
Hyperchromic effect
(iii) Valence Bond theory, comparative study and relation of colour in the following classes of
compounds/dyes: Benzene, Nitrobenzene, Nitroanilines, Nitrophenols, Benzoquinones, Azo, Triphenyl
methane, Anthraquinones.
(iv) Molecular Orbital Theory.
4.2 Unit process and Dye Intermediates
4.2.1 A brief idea of Unit Processes (3L)
Introduction to primaries and intermediates Unit processes: definition and brief ideas of below unit
processes: (a) Nitration (b) Sulphonation (c) Halogenation (d) Diazotization: (3 different methods & its
importance) (e) Ammonolysis (f) Oxidation
NB: Definition, Reagents, Examples of each unit processes mentioned above with reaction conditions
(mechanism is not expected)
4.2.2 Preparation of the Following Intermediates (8L)
Benzene derivatives: Benzenesulphonic acid; 1,3-Benzenedisulphonic acid; sulphanilic acid; o-, m-, p-
chloronitrobenzenes; o-, m-, p-nitroanilines; o-, m-, p-phenylene diamines; Naphthol ASG Naphthalene
Derivative: Schaeffer acid; Tobias acid; Naphthionic acid; N.W. acid; cleve-6-acid; H-acid; Naphthol AS

DEPARTMENT OF CHEMISTRY
Anthracene Derivative: 1-Nitroanthraquinone; 1-Aminoanthraquinone Anthraquinone-2-sulphonic acid;
Benzanthrone.
Reference Books: (For units I & II)
1. Foye's principles of medicinal chemistry. 6th Edition, Edited by Davis William & Thomas Lemke,
Indian edition by B I Publication Pvt Ltd, Lippmcolt Williams & Wilkins.
2. Text book of organic medicinal & pharmaceutical chemistry. Wilson & Gisovolds, 11th Edition by John
H Block, John M Beale Jr.
3. Medicinal chemistry. Ashutosh Kar, New Age International Pvt. Ltd Publisher. 4th edition.
4. Burger’s Medicinal Chemistry, Drug Discovery and Development. Abraham and Rotella. Wiley
5. Medicinal chemistry. Ashutosh Kar, New Age International Pvt. Ltd Publisher. 4th edition.
6. Medicinal chemistry. V.K. Ahluwalia and Madhu Chopra, CRC Press.
7. Principle of medicinal chemistry. Vol 1 &2 S. S. Kadam, K. R. Mahadik, K. G. Bothara
8. The Art of Drug synthesis. Johnson and Li. Wiley, 2007.
9. The organic chemistry of drug design & drug action. 2nd ed. By Richard B Silvermann, Academic
Press.
10. The Organic Chemistry of Drug Synthesis. Lednicer and Mitsher, Wliey.
References (For Units III & IV):
1. Chemistry of Synthetic Dyes, Vol I – VIII, Venkatraman K., Academic Press 1972
2. The Chemistry of Synthetic Dyes and Pigments, Lubs H.A., Robert E Krieger Publishing Company,
NY ,1995
3. Chemistry of Dyes and Principles of Dyeing, Shenai V.A., Sevak Publications, 1973
Scheme of Examination
Semester End Theory Examinations:
There will be a Semester-end external Theory examination of 100 marks for each of the courses
USCH501, USCH502, USCH503, USCH504, USACDD501 of Semester V to be conducted by the
University.
1. Duration: The examinations shall be of 3 Hours duration.

2. Theory Question Paper Pattern:

a) There shall be FIVE questions. The first four questions Q.1, Q.2. Q.3, Q.4 shall be of 20 marks,
each based on the units I, II, III & IV respectively. The fifth question Q.5 shall be of objective
type for 20 marks based on the entire syllabus consisting of multiple choice questions, match the

DEPARTMENT OF CHEMISTRY
 following, true/false etc.
b) All the questions shall be compulsory. The questions Q.1, Q.2, Q.3, Q.4 shall have internal
choices within the questions. Including the choices, the marks for each question shall be 30.
c) The questions Q.1, Q.2, Q.3, Q.4 may be subdivided into sub-questions as A, B, C, D, E & F.
E & F.
QUESTION PAPER PATTERN:

Q. 1 Attempt any four from A/B/C/D/E/F Unit I Marks 20

Q. 2 Attempt any four from A/B/C/D/E/F Unit II Marks 20
Q. 3 Attempt any four from A/B/C/D/E/F Unit III Marks 20
Q. 4 Attempt any four from A/B/C/D/E/F Unit IV Marks 20
Q.5 Based On Unit I, II, III & IV.
(A) Select the correct option and complete the following sentences. (any five) 05
(B) State whether the following statements are true or false. (any five) 05
(C) State true or false. (attempt any five) 05
(C) Match the column. (any five) 05

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Physical Chemistry Practical

Program Code:1S00145 Course Code: USCHP01

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course outcome:
Upon completion of this course the students will be able to:
CO1 Calculate the rate of the reaction by using conductometer.
CO2 Determine isoelectric point of proteins which is important for the purification of the proteins.
CO3 Learn to determine the molecular weight of the compound by employing the principle of depression
of freezing point.
CO4 Understand the concept of fractional change method and able to find out the order of reaction by
fractional change method
CO5 Find out the validity of Freundlich adsorption isotherm.
Syllabus:
Non-Instrumental
1. Colligative properties: To determine the molecular weight of compound by Rast Method
2. Chemical Kinetics: To determine the order between K2S2O8 and KI by fractional change method.
3. Surface phenomena: To investigate the adsorption of acetic acid on activated charcoal and test the
validity of Freundlich adsorption isotherm.
Instrumental
1. Potentiometry: To determine the solubility product and solubility of AgCl potentiometrically using
chemical cell.
2. Conductometry: To determine the velocity constant of alkaline hydrolysis of ethyl acetate by
conductometric method.
3. pH-metry: To determine acidic and basic dissociation constants of amino acid and hence to calculate

DEPARTMENT OF CHEMISTRY
isoelectric point.

Reference books

1. Practical Physical Chemistry 3rd edition A. M. James and F.E. Prichard, Longman publication

2. Experiments in Physical Chemistry R.C. Das and B. Behra, Tata Mc Graw Hill

3. Advanced Practical Physical Chemistry J. B. Yadav, Goel Publishing House

4. Advanced Experimental Chemistry. Vol-I J. N. Gurtu and R Kapoor, S. Chand and Co.

5. Experimental Physical Chemistry By V. D. Athawale.

6. Senior Practical Physical Chemistry By: B. D. Khosla, V. C. Garg and A. Gulati, R Chand and
Co. 2011

: Question Paper Pattern:

Maximum Marks: 50 Marks

Time: 3.5 Hours

Note: 1) Attempt all Questions

1. Perform given Instrumental or Non-instrumental experiment and tabulate the result as per
guidelines. 40 marks

2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks

Detailed scheme of marking of Experiment.

(1) Technique : 04 marks

Instrumental
(2) Reading : 14 marks
Or
(3) Graph & Calculations : 12 marks
Non-instrumental
(4) Accuracy : 10 marks
Experiment
Total marks : 40 marks

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Inorganic Chemistry Practical

Program Code: 1S00145 Course Code: USCHP05

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcomes:

Upon completion of this course the students will be able to:

CO1 Understand key concepts of inorganic synthesis, reaction chemistry, and structure and bonding.
CO2 Assign IUPAC names to the inorganic complexes.
CO3 Determine the percentage purity of water soluble salt.
CO4 Perform qualitative analysis of cation or anion by only wet test method.

I. Inorganic preparations
1. Preparation of Potassium diaquobis- (oxalato) cuprate (II)
2. Preparation of Ferrous ethylene diammonium sulphate.
3. Preparation of bis-acetylacetonato copper(II)
II. Determination of percentage purity of the given water soluble salt and qualitative detection w.r.t added
cation and/or anion (qualitative analysis only by wet tests). (Any three salts of transition metal ions)
Reference Books
1. Vogel Textbook of Quantitative Chemical Analysis G.H. Jeffery, J. Basset.
2. Advanced experiments in Inorganic Chemistry., G. N. Mukherjee., 1st Edn, 2010, U. N. Dhur & Sons
Pvt Ltd .
3. Vogel's. Textbook of. Macro and Semimicro qualitative inorganic analysis. Fifth edition.8.Gregory.N.
Mankiw, Macroeconomics, Fifth Edition (2002) New York: Worth Publishers

DEPARTMENT OF CHEMISTRY
 : Question Paper Pattern :
Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform a) Given preparation of inorganic complex and
b) Perform given volumetric analysis.

No. Exercise Marks

1. Inorganic preparation 20
2. Volumetric analysis 20
3. Vivo-voce 05
4. Journal 05
Total 50

 Detailed Marking Scheme for Inorganic Preparation

Errors (mL) Marks

8 12
 10 10
 15 08
 18 06
Above  18 00
Quality of product 04
Calculation 04
Total 20

 Detailed Marking Scheme for Volumetric analysis

Errors (mL) Marks

 0.2 12
 0.3 10
 0.4 08
 0.5 06
 0.6 and above 00
Calculation 04
Systematic work 04
Total 20

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Organic Chemistry Practical

Program Code:1S00145 Course Code: USCHP09

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Identify chemical type of components present in binary mixture.
CO2 Carry out separation of solid-solid binary mixture on the basis of difference in chemical properties.
CO3 Identify the unknown organic compound by systematic qualitative microscale technique.
CO4 Determine the purity, and percent yield of components.
CO5 Summarize findings in writing in a clear and concise manner.
CO6 Learn the reactivity of various functional groups.

SEMESTER V: Separation of Binary solid-solid mixture (2.0 gms mixture to be given).

1. Minimum Six mixtures to be completed by the students.
2. Components of the mixture should include water soluble and water insoluble acids (carboxylic acid),
water insoluble phenols( 2-naphthol, 1-naphthol), water insoluble bases (nitroanilines) , water soluble
neutral (thiourea) and water insoluble neutral compounds (anilides , amides, m-DNB, hydrocarbons).
After correct determination of chemical type, the separating reagent should be decided by the student for
separation.
4. Follow separation scheme with the bulk sample of binary mixture.
5. After separation into component A and component B, one component (decided by the examiner) is to
be analyzed and identified with m.p.

DEPARTMENT OF CHEMISTRY
Reference Books
1. Practical organic chemistry – A. I. Vogel
2. Practical organic chemistry – H. Middleton.
3. Practical organic chemistry – O. P. Aggarwal.

: Question Paper Pattern :

Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform a) Separation of given solid + volatile liquid or volatile liquid + Non-volatile liquid organic
Mixture and find out its type.
b) Perform organic qualitative analysis of given organic compound.

No. Exercise Marks

1. Separation of binary mixture 20
2. Qualitative analysis of given organic compound 20
3. Vivo-voce 05
4. Journal 05
Total 50

Detailed Marking Scheme:

Chemical Type 04
Yield 08
Quality 04
Preliminary test 03
Elements 04
Functional Group 04
Melting point 04
Confirmatory Test 02
Name & structure 02
Technique & 05
systematic work
Journal 05
Viva-voce 05
Total 50

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Analytical Chemistry Practical

Program Code: 1S00145 Course Code: USCHP13

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Determine COD in water sample.
CO2 Estimate the fluoride content in sample by using spectrophotometer.
CO3 Find out potassium content in fertilizer sample by using flame photometry.
CO4 Know how to calculate amount of SO42- in water sample by using turbidimeter.
CO5 Determine the amount of persulphate in sample titrimetrically.
CO6 Estimate the magnesium content in talcum powder by complexometric titration.
CO7 Plot statistical data to calculate answer.

Syllabus:
1. Spectrophotometric estimation of fluoride.
2 Estimation of magnesium content in Talcum powder by complexometry, using standardized solution of
EDTA
3 Determination of COD of water sample.
4 To determine potassium content of a Fertilizer by Flame Photometry (Calibration curve method).
5 To determine the amount of persulphate in the given sample solution by back titration with standard Fe
(II) ammonium sulphate solution.
6 To determine the amount of sulphate in given water sample turbidimetrically.

DEPARTMENT OF CHEMISTRY
References:
1. Vogel’s Textbook of Quantitative Chemical Analysis, 5th Edn., G. H. Jeffery, J Bassett, J Memdham
and R C Denney, ELBS with Longmann (1989).
2. Vogel's Textbook of Quantitative Chemical analysis, Sixth edition, J. Mendham et.al

: Question Paper Pattern :

Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform given Instrumental or Non-instrumental experiment and tabulate the result as per guidelines.
40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
Detailed scheme of marking of Instrumental Experiment.

Technique 04 marks
Observations 12 marks
Calculation 06 marks
Graph 06 marks
Accuracy 12 marks
Total 40 marks

Detailed scheme of marking of Non-Instrumental Experiment.

Observation 26
Reaction 02
Calculation 08
Systematic work 04
Total 40

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus
Programmme: B. Sc. Course: Chemistry
Drugs & Dyes Practical

Program Code: 1S00145 Course Code: USACDD5P1

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : V

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 perform laboratory synthesis of simple drug molecules like aspirin.
CO2 Estimate the amount of Ibuprofen.
CO3 find out acid neutralizing capacity of antacid
CO4 Design and execute the synthesis of Orange II dye and learn the process of dyeing of fabric.
CO5 communicate scientific information clearly and accurately, both in oral and in written forms.

1. Estimation of Ibuprofen (back titration method)

2. Estimation of Acid neutralizing capacity of a drug
3. Preparation of Aspirin from salicylic acid.
4. Separation of components of natural pigments by paper chromatography (e g: chlorophyll)
II] Project: Preparation of Orange II dye (semi-microscale1.0gms) and its use for dyeing different fabrics.

: Question Paper Pattern :

Maximum Marks: 100 Marks
Time: 3.5 Hours + 3.5 Hours
Q. Perform given preparation of compound and estimation of sample solution.
1. Preparations 40 marks
2 Estimation 40 marks
3. Project Work & Journal 10 marks
4. Viva-voce 10 marks
Total 100 marks

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Physical Chemistry

Program Code: 1S00146 Course Code:USCH601

(As per the Credit Based Semester and Grading System with effect from the academic year 2018-19)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Classify the cells & write the cell reactions.
CO2 Determine the decomposition potential & over-voltage.
CO3 Calculate the molar mass of polymers by different methods.
CO4 Know the additives in polymers & applications in terms of Light Emitting Polymers.
CO5 understand and explain the differences between classical and quantum mechanics.
CO6 understand the idea of wave function & operators.
CO7 Solve Schrodinger’s equation for particle in one dimensional box.
CO8 Explain the importance of renewable energy and their sources.
CO9 Learn principle and instrumentation of NMR & ESR spectroscopy.

UNIT I
1.1 ELECTROCHEMISTRY (7L)
1.1.1 Activity and Activity Coefficient: Lewis concept, ionic strength, Mean ionic activity and mean ionic
activity coefficient of an electrolyte, expression for activities of electrolytes. Debye-Huckel limiting law
(No derivation).
1.1.2 Classification of cells: Chemical cells and Concentration cells. Chemical cells with and without
transference, Electrode Concentration cells, Electrolyte concentration cells with and without transference
(derivations are expected),
1.2 APPLIED ELECTROCHEMISTRY (8L)

DEPARTMENT OF CHEMISTRY
1.2.1 Polarization: concentration polarization and it’s elimination.
1.2.2 Decomposition Potential and Overvoltage: Introduction, experimental determination of
decomposition potential, factors affecting decomposition potential. Tafel’s equation for hydrogen
overvoltage, experimental determination of over –voltage.
UNIT II
2.0 POLYMERS (15L)
2.1 Basic terms: macromolecule, monomer, repeat unit, degree of polymerization.
2.2. Classification of polymers: Classification based on source, structure, thermal response and physical
properties.
2.3. Molar masses of polymers: Number average, Weight average, Viscosity average molar mass,
Monodispersity and Polydispersity
2.4. Method of determining molar masses of polymers: Viscosity method using Ostwald Viscometer.
(derivation expected)
2.5. Light Emitting Polymers: Introduction, Characteristics, Method of preparation and applications.
2.6. Antioxidants and Stabilizers: Antioxidants, Ultraviolet stabilizers, Colourants, Antistatic agents and
Curing agents.
UNIT III
3.1 BASICS OF QUANTUM CHEMISTRY (10 L)
3.1.1 Classical mechanics: Introduction, limitations of classical mechanics, Black body radiation,
photoelectric effect, Compton effect.
3.1.2 Quantum mechanics: Introduction, Planck’s theory of quantization, wave particle duality, de –
Broglie’s equation, Heisenberg’s uncertainty principle.
3.1.3 Progressive and standing waves- Introduction, boundary conditions, Schrodinger’s time independent
wave equation (No derivation expected), interpretation and properties of wave function.
3.1.4 Quantum mechanics: State function and its significance, Concept of operators - definition, addition,
subtraction and multiplication of operators, commutative and non - commutative operators, linear
operator, Hamiltonian operator, Eigen function and Eigen value.
3.2 RENEWABLE ENERGY RESOURCES (5L)
3.2.1. Renewable energy resources: Introduction.
3.2.2 Solar energy: Solar cells, Photovoltaic effect, Differences between conductors, semiconductors
,insulators and its band gap, Semiconductors as solar energy converters, Silicon solar cell

DEPARTMENT OF CHEMISTRY
3.2.3. Hydrogen : Fuel of the future, production of hydrogen by direct electrolysis of water, advantages of
hydrogen as a universal energy medium
UNIT IV
4.1 NMR -NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (7L)
4.1.1. Principle : Nuclear spin, magnetic moment, nuclear ‘g’ factor, energy levels, Larmor precession,
Relaxation processes in NMR ( spin -spin relaxation and spin - lattice relaxation).
4.1.2. Instrumentation: NMR Spectrometer
4.2 ELECTRON SPIN RESONANCE SPECTROSCOPY (8 L)
4.2.1. Principle: fundamental equation, g-value -dimensionless constant or electron g-factor, hyperfine
splitting.
4.2.2. Instrumentation: ESR spectrometer, ESR spectrum of hydrogen and deuterium.
References:
1. Physical Chemistry, Ira Levine, 5th Edition, 2002 Tata McGraw Hill Publishing Co.Ltd.
2. Physical Chemistry, P.C. Rakshit, 6th Edition, 2001, Sarat Book Distributors, Kolkota.
3. Physical Chemistry, R.J. Silbey, & R.A. Alberty, 3rd edition , John Wiley & Sons, Inc [part 1]
4. Physical Chemistry, G. Castellan, 3rd edition, 5th Reprint, 1995 Narosa Publishing House.
5. Modern Electrochemistry, J.O.M Bockris & A.K.N. Reddy, Maria Gamboa – Aldeco 2nd Edition, 1st
Indian reprint,2006 Springer
6. Fundamental of Molecular Spectroscopy, 4th Edn., Colin N Banwell and Elaine M McCash Tata
McGraw Hill Publishing Co. Ltd. New Delhi, 2008.
7. Physical Chemistry, G.M. Barrow, 6th Edition, Tata McGraw Hill Publishing Co. Ltd. New Delhi.
8. The Elements of Physical Chemistry, P.W. Atkins, 2nd Edition, Oxford Universtity Press Oxford.
9. Physical Chemistry, G.K. Vemullapallie, 1997, Prentice Hall of India, Pvt.Ltd. New Delhi.
10. Principles of Physical Chemistry B.R. Puri, L.R. Sharma, M.S. Pathania, VISHAL PUBLISHING
Company, 2008.
11. Textbook of Polymer Science, Fred W Bilmeyer, John Wiley & Sons (Asia) Ple. Ltd., Singapore,
2007.
12. Polymer Science, V.R. Gowariker, N.V. Viswanathan, Jayadev Sreedhar, New Age International (P)
Ltd., Publishers, 2005.
13. Essentials of Nuclear Chemistry, Arnikar, Hari Jeevan , New Age International (P) Ltd., Publishers,
2011..

DEPARTMENT OF CHEMISTRY
14. Chemical Kinetics,K. Laidler, Pearson Education India, 1987.

S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Inorganic Chemistry

Program Code: 1S00146 Course Code:USCH602

(As per the Credit Based Semester and Grading System with effect from the academic year 2018-19)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Explains many important properties of transition-metal complexes, including their colors,
magnetism, structures, stability, and reactivity.
CO2 Know the splitting pattern of d orbitals in octahedral crystal field.
CO3 Identify the strong and weak field ligands.
CO4 Evaluate the extent of splitting in octahedral complexes.
CO5 Explain the formation of coordinate compounds by using Molecular Orbital Theory.
CO6 Learn thermodynamics and kinetics of metal complex formation.
CO7 Understand the origin of electronic spectra & types of electronic transitions
CO8 Calculate number of microstates
CO9 Determine the Terms for p2 and d1 electronic configurations.
CO10 Know how to prepare organometallic compounds and their use in chemical reactions.
CO11 Write the general characteristics, properties and uses of noble gases.
CO12 Understand the role of metal ions in biological systems.

Unit I
1.Theories of the metal-ligand bond (I) (15L)
1.1 Limitations of Valence Bond Theory.
1.2 Crystal Field Theory and effect of crystal field on central metal valence orbitals in various geometries

DEPARTMENT OF CHEMISTRY
from linear to octahedral (from coordination number 2 to coordination number 6)
1.3 Splitting of d orbitals in octahedral, square planar and tetrahedral crystal fields.
1.4 Distortions from the octahedral geometry: (i) effect of ligand field and (ii) Jahn-Teller distortions.
1.5 Crystal field splitting parameters Δ; its calculation and factors affecting it in octahedral complexes,
Spectrochemical series.
1.6 Crystal field stabilization energy (CFSE), calculation of CFSE for octahedral complexes with d0 to d10
metal ion configurations.
1.7 Consequences of crystal field splitting on various properties such as ionic radii, hydration energy and
enthalpies of formation of metal complexes of the first transition series.
1.8 Limitations of CFT: Evidences for covalence in metal complexes (i) intensities of d-d transitions, (ii)
ESR spectrum of [IrCl6]2- (iii) Nephelauxetic effect.
UNIT-II
2.Theories of the metal-ligand bond (II)
2.1 Molecular orbital Theory for coordination compounds. (4L)
2.1.1 Identification of the central metal orbitals and their symmetry suitable for formation of σ bonds with
ligand orbitals.
2.1.2 Construction of ligand group orbitals.
2.1.3 Construction of σ-molecular orbitals for an ML6 complex.
2.1.4 Effect of π-bonding on complexes.
2.1.5 Examples like [FeF6]-4, [Fe(CN)6]-4, [FeF6]-3, [Fe(CN)6]-3, [CoF6]-3, [Co(NH3)6]+3
2.2 Stability of Metal-Complexes (4L)
2.2.1 Thermodynamic and kinetic perspectives of metal complexes with examples.
2.2.2 Stability constants: stepwise and overall stability constants and their interrelationship.
2.2.3 Factors affecting thermodynamic stability.
2.3 Reactivity of metal complexes. (4L)
2.3.1 Comparison between Inorganic and organic reactions.
2.3.2 Types of reactions in metal complexes.
2.3.3 Inert and labile complexes: correlation between electronic configurations and lability of complexes.
2.3.4 Ligand substitution reactions: Associative and Dissociative mechanisms.
2.2.5 Acid hydrolysis, base hydrolysis and anation reactions.
2.4 Electronic Spectra. (3L)

DEPARTMENT OF CHEMISTRY
2.4.1Origin of electronic spectra
2.4.2 Types of electronic transitions in coordination compounds: intra- ligand, Charge transfer and intra-
metal transitions.
2.4.3 Selection rules for electronic transitions.
2.4.4 Electronic configuration and electronic micro states, Terms and Term symbols for transition metal
ions, rules for determination of ground state term.
2.4.5 Determination of Terms for p2 and d1 electronic configurations.
UNIT-III
ORGANOMETALLIC CHEMISTRY (15L)
3.1 Organometallic Compounds of main group metal (6L)
3.1.1General characteristics of various types of organometallic compounds, viz. ionic, σ-bonded and
electron deficient compounds.
3.1.2 General synthetic methods of organometallic compounds : (i) Oxidative-addition, (ii)Metal-metal
Exchange (transmetallation), (iii) Carbanion-halide exchange, (iv) Metal-hydrogen exchange (metallation)
and (v) Methylene-insertion reactions.
3.1.3 Some chemical reactions of organometallic compounds: (i) Reactions with oxygen and halogens, (ii)
Alkylation and arylation reactions (iii) Reactions with protic reagents, (iv) Redistribution reactions and
(v) Complex formation reactions.
3.2 Metallocenes (5L)
Introduction, Ferrocene: Synthesis, properties, structure and bonding on the basis of VBT.
3.3 Catalysis (4L)
3.3.1 Comparison between homogeneous and heterogeneous catalysis
3.3.2 Basic steps involved in homogeneous catalysis
3.3.3 Mechanism of Wilkinson’s catalyst in hydrogenation of alkenes.
UNIT-IV
SOME SELECTED TOPICS (15L)
4.1 Metallurgy ( 7L)
4.1.1 Types of metallurgies,
4.1.2 General steps of metallurgy; Concentration of ore, calcinations, roasting, reduction and refining.
4.1.3 Metallurgy of copper: occurrence, physicochemical principles, Extraction of copper from pyrites&
refining by electrolysis.

DEPARTMENT OF CHEMISTRY
4.2 Chemistry of Group 18 (5L)
4.2.1 Historical perspectives
4.2.2 General characteristics and trends in physical and chemical properties
4.2.3 Isolation of noble gases
4.2.4 Compounds of Xenon (oxides and fluorides) with respect to preparation and structure (VSEPR)
4.2.5 Uses of noble gases
4.3 Introduction to Bioinorganic Chemistry. (3L)
4.3.1Essential and nonessential elements in biological systems.
4.3.2 Biological importance of metal ions such as Na+,K+,Fe+2/Fe+3 and Cu+2 (Role of Na+ and K+ w.r.t
ion pump)

References:
Unit-I:
1. Geoffrey A. Lawrance Introduction to Coordination Chemistry John Wiley & Sons.
2. R. K. Sharma Text Book of Coordination Chemistry Discovery Publishing House
3. R. Gopalan , V. Ramalingam Concise Coordination Chemistry , Vikas Publishing House;
4. Shukla P R, Advance Coordination Chemistry , Himalaya Publishing House
5. Glen E. Rodgers, Descriptive Inorganic, Coordination, and Solid-State Chemistry Publisher: Thomson
Brooks/Cole
Unit-II:
1. Ramesh Kapoor and R.S. Chopra, Inorganic Chemistry, R. Chand publishers,
2. Basolo, F, and Pearson, R.C., Mechanisms of Inorganic Chemistry, John Wiley & Sons, NY,
3. Twigg ,Mechanisms of Inorganic and Organometallic Reactions Publisher: Springer
4 R.K. Sharma Inorganic Reaction Mechanisms Discovery Publishing House
5 M. L. Tobe Inorganic Reaction Mechanisms Publisher Nelson, 1972
Unit-III:
1 Cotton, Wilkinson, Murillo and Bochmann, Advanced Inorganic Chemistry, 6th Edition.
2 H.W. Porterfield, Inorganic Chemistry, Second Edition, Academic Press, 2005
3 Purecell, K.F. and Kotz, J.C., Inorganic Chemistry W.B. Saunders Co. 1977.
4 Robert H. Crabtree ,The Organometallic Chemistry of the Transition Metals, Publication by John Wiley
& Sons

DEPARTMENT OF CHEMISTRY
5 B D Gupta & Anil J Elias Basic Organometallic Chemistry: Concepts, Syntheses and Applications,
University press
6 Ram Charan Mehrotra, Organometallic Chemistry: A Unified Approach, New Age International.
Unit-IV
1 R. Gopalan, Inorganic Chemistry for Undergraduates, Universities Press India.
2 D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press
3 Cotton, Wilkinson, Murillo and Bochmann, Advanced Inorganic Chemistry, 6th Edition.
4 Jack Barrett and Mounir A Malati, Fundamentals of Inorganic Chemistry, Affiliated East west Press
Pvt. Ltd., New Delhi.
5 R. Gopalan, Chemistry for undergraduates. Chapter 18. Principles of Metallurgy.(567-591)
6 Puri, Sharma Kalia Inorganic chemistry. Chapter 10, Metals and metallurgy.(328-339)
7 Greenwood, N.N. and Earnshaw, Chemistry of the Elements, Butterworth Heinemann. 1997.
8 Huheey, J.E., Inorganic Chemistry, Prentice Hall, 1993.
9 Lippard, S.J. & Berg, J.M. Principles of Bioinorganic Chemistry Panima Publishing Company 1994.
10 Satya Prakash, G. D. Tuli, R.D. Madan, Advanced Inorganic Chemistry. S. Chand & Co Ltd

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Organic Chemistry

Program Code: 1S00146 Course Code:USCH603

(As per the Credit Based Semester and Grading System with effect from the academic year 2018-19)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Predict the stereochemistry of substitution, addition and elimination reactions.
CO2 Know about formation of proteins and their different types of structures.
CO3 Predict the mechanism of some name reactions with stereochemical aspects.
CO4 Learn how to classify and determine the structure, how to synthesis of carbohydrates and reactions
thereof.
CO5 Use nuclear magnetic resonance spectroscopy, mass spectrometry and infrared spectroscopy
techniques for organic structure elucidation.
CO6 Understand how nucleic acids are made up of and their structures.
CO7 Know the types of polymers, their preparations and how to identify monomeric units present.

Unit I
1.1 Stereochemistry II (10 L)
1.1.1 Stereoselectivity and stereospecificity: Idea of enantioselectivity (ee) and diastereoselectivity
(de) , Topicity : enantiotopic and diasterotopic atoms, groups and faces.
1.1.2 Stereochemistry of – i) Substitution reactions : SNi (reaction of alcohol with thionyl chloride)
ii) Elimination reactions: E2–Base induced dehydrohalogenation of 1-bromo-1, 2-diphenylpropane.
iii) Addition reactions to olefins: a) bromination (electrophilic anti addition) b) syn hydroxylation with
OsO4 and KMnO4 c) epoxidation followed by hydrolysis.
1.2 Amino acids & Proteins (5 L)

DEPARTMENT OF CHEMISTRY
1.2.1 α-Amino acids: General Structure, configuration, and classification based on structure and nutrition.
Properties: pH dependency of ionic structure, isoelectric point and zwitter ion. Methods of preparations:
Strecker synthesis, Gabriel phthalamide synthesis.
1.2.2 Polypeptides and Proteins: nature of peptide bond. Nomenclature and representation of polypeptides
(di-and tri-peptides) with examples Merrifield solid phase polypeptide synthesis. Protiens: general idea of
primary, secondary, tertiary & quaternary structure
Unit II
2.1 Molecular Rearrangements (5 L)
Mechanism of the following rearrangements with examples and stereochemistry wherever applicable.
2.1.1 Migration to the electron deficient carbon: Pinacol-pinacolone rearrangement.
2.1.2 Migration to the electron deficient nitrogen: Beckmann rearrangement.
2.1.3 Migration involving a carbanion: Favorski rearrangement.
2.1.4 Name reactions: Michael addition, Wittig reaction.
2.2 Carbohydrates (10 L)
2.2.1 Introduction: classification, reducing and non-reducing sugars, DL notation
2.2.2 Structures of monosaccharides: Fischer projection (4-6 carbon monosaccharides) and Haworth
formula (furanose and pyranose forms of pentoses and hexoses) Interconversion: open chain and Haworth
forms of monosaccharides with 5 and 6 carbons. Chair conformation with stereochemistry of D-glucose,
Stability of chair form of D-glucose
2.2.3 Stereoisomers of D-glucose: enantiomer, diastereomers, anomers, epimers.
2.2.4 Mutarotation in D-glucose with mechanism
2.2.5 Chain lengthening & shortening reactions: Modified Kiliani-Fischer synthesis (D-arabinose to
D-glucose and D-mannose), Wohl method (D-glucose to D-arabinose)
2.2.6 Reactions of D-glucose and D-fructose:
(a) Osazone formation (b) reduction: Hi/Ni, NaBH4 (c) oxidation: bromine water, HNO3, HIO4
(d) acetylation (e) methylation:(d) and (e) with cyclic pyranose forms
2.2.7 Glycosides: general structure
Unit III
3.1 Spectroscopy II (10 L)
3.1.1 IR Spectroscopy: Basic theory, nature of IR spectrum, selection rule, fingerprint region.
3.1.2 PMR Spectroscopy: Basic theory of PMR, nature of PMR spectrum, chemical shift (δ unit), standard

DEPARTMENT OF CHEMISTRY
for PMR, solvents used. Factors affecting chemical shift: (1) inductive effect (2) anisotropic effect (with
reference to C=C, C≡C, C=O and benzene ring). Spin- spin coupling and coupling constant. application of
deuterium exchange technique. application of PMR in structure determination.
3.1.3 Spectral characteristics of following classes of organic compounds, including benzene and
monosubstituted benzenes, with respect to IR and PMR: (1) alkanes (2) alkenes (3) alkynes (4)
haloalkanes (5) alcohols (6) carbonyl compounds (7) ethers (8) amines (broad regions characteristic of
different groups are expected). Problems of structure elucidation of simple organic compounds using
individual or combined use of UV-Vis, IR, Mass and NMR spectroscopic technique are expected. (Index
of hydrogen deficiency should be the first step in solving the problems).
3.2 Nucleic Acids (5 L)
Controlled hydrolysis of nucleic acids. sugars and bases in nucleic acids. Structures of nucleosides and
nucleotides in DNA and RNA. Structures of nucleic acids (DNA and RNA) including base pairing.
Unit IV
4.1 Polymer (8 L)
4.1.1 Introduction: terms monomer, polymer, homopolymer, copolymer, thermoplastics and thermosets.
4.1.2 Addition polymers: polyethylene, polypropylene, teflon, polystyrene, PVC, Uses.
4.1.3 Condensation polymers: polyesters, polyamides, polyurethanes, polycarbonates, phenol
formaldehyde resins. Uses
4.1.4 Stereochemistry of polymers: Tacticity, mechanism of stereochemical control of polymerization
using Ziegler Natta catalysts.
4.1.5 Natural and synthetic rubbers: Polymerisation of isoprene: 1, 2 and 1, 4 addition (cis and trans),
Styrene butadiene copolymer.
4.1.6 Additives to polymers: Plasticisers, stabilizers and fillers.
4.1.7 Biodegradable polymers: Classification and uses. polylactic acid structure, properties and use for
packaging and medical purposes.
4.2 Catalysts and Reagents (7 L)
Study of the following catalysts and reagents with respect to functional group transformations and
selectivity (no mechanism).
4.2.1 Catalysts: Catalysts for hydrogenation:
a. Raney Nickel b. Pt and PtO2 ( C=C, CN, NO2, aromatic ring) c. Pd/C : C=C, COCl→CHO
(Rosenmund) d. Lindlar catalyst: alkynes

DEPARTMENT OF CHEMISTRY
4.2.2 Reagents: a. LiAlH4 (reduction of CO, COOR, CN,NO2) b. NaBH4 (reduction of CO) c. SeO2
(Oxidation of CH2 alpha to CO) d. mCPBA (epoxidation of C=C) e. NBS (allylic and benzylic
bromination)
References:
1. L. Eliel , stereochemistry of carbon compounds, Tata McGraw Hill
2. Stereochemistry P. S. Kalsi , New Age International Ltd.,4th Edition
3. Stereochemistry by Nassipuri.
4. Biochemistry, 8th Ed., Jeremy Berg, Lubert Stryer, John L. Tymoczko, Gregory J. Gatto Pub. W. H.
Freeman Publishers
5. Lehninger Principles of Biochemistry 7th Ed., David Nelson and Michael Cox, Publisher W. H.
Freeman
6. Name Reactions – Jie Jack Li, 4th Edition, Springer Pub.
7. A guidebook to mechanism in Organic Chemistry, 6th edition, Peter Sykes, Pearson education, New
Delhi
8. Organic Reaction Mechanism, 4th edition, V. K. Ahluwalia, R. K. Parashar, Narosa Publication.
9. Organic reactions & their mechanisms,3rd revised edition, P.S. Kalsi, New Age International
Publishers.
10. M.B.Smith and J. March, Advanced organic chemistry- reactions mechanism and structure, 5th
edition.
11. Organic chemistry (fourth edition),G, Marc Loudon, Oxford University press.
12. Introduction to Organic Chemistry (Third edition), Andrew Streitwieser, Jr. Clayton H. Heathcock,
Macmilan publishing.
13. Organic chemistry fourth edition, Morrision and Boyd.
14. Introduction to Organic chemistry, John Mc Murry.
15. Organic chemistry volume-1&2 (fifth and sixth edition) IL Finar.
16. Organic spectroscopy (Second edition),Jag Mohan ,Narosa publication
17. Spectroscopy, Pavia, Lampman, Kriz, Vyvyan.
18. Elementary organic spectroscopy (Third edition), Y. R. Sharma, S. Chand publication.
19. Introduction to spectroscopy (third edition), Pavia, Lampman, Kriz,john vondeling, Emily Barrosse.
20. Organic chemistry Paula Y. Bruice, Pearson education.
21. Spectral identification of organic molecules by Silverstein.

DEPARTMENT OF CHEMISTRY
22. Absorption spectroscopy of organic molecules by V. M. Parikh.
23. Organic chemistry R. T .Morrison and R. N. Boyd, 6th edition, pearson education
24. S. H. Pine, organic chemistry 4th edition. McGraw Hill
25. Polymer chemistry by M. G. Arora, K. Singh.
26. Polymer science – a text book by Ahluwalia and Mishra
27. Introduction to polymer chemistry - R. Seymour, Wiley Interscience.
28. Organic chemistry by Francis Carey – McGraw Hill
29. Organic chemistry by Carey and Sundberg, Part A & B

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Analytical Chemistry

Program Code: 1S00146 Course Code:USCH604

(As per the Credit Based Semester and Grading System with effect from the academic year 2018-19)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Understand the basics of electroanalytical techniques and their applications in analysis.
CO2 Know the basic theory, principle, instrumentation & use in qualitative and quantitative analysis.
CO3 Learn about ion exchange chromatography and its use demineralisation of water, Separation of
amino acids
CO4 Learn about analysis of ingredients used food chemistry & cosmetic industry.
CO5 Become familiar with various thermal methods of analysis and various method validation parameters
and their importance.
CO6 Know the importance and need for analytical validation of a method.
UNIT I: ELECTRO ANALYTICAL TECHNIQUES
1.1 Polarography (Numerical and word problems are expected) (11L)
1.1.1 Difference between potentiometry and voltammetry, Polarizable and non-polarizable electrodes
1.1.2 Basic principle of polarography H shaped polarographic cell, DME (construction, working,
advantages and limitations)
1.1.3 DC polarogram: Terms involved - Residual current, Diffusion current, Limiting current, Half-Wave
Potential Role and selection of supporting electrolyte, Interference of oxygen and its removal,
polarographic Maxima and Maxima Suppressors Qualitative aspects of Polarography: Half wave potential
E1/2, Factors affecting E1/2
Quantitative aspects of polarography: Ilkovic equations: various terms involved in it (No derivation)
1.1.4 Quantification
1) Wave height – Concentration plots (working plots/calibration)

DEPARTMENT OF CHEMISTRY
2) Internal standard (pilot ion) method
3) Standard addition method
1.1.5 Applications advantages and limitations
1.2 Amperometric Titrations (4L)
1.2.1 Principle, Rotating Platinum Electrode(Construction, advantages and limitations)
1.2.2 Titration curves with example
1.2.3 Advantages and limitations
UNIT II: METHODS OF SEPARATION – II
2.1 Gas Chromatography (Numerical and word problems are expected) (9 L)
2.1.1 Introduction, Principle, Theory and terms involved
2.1.2 Instrumentation: Block diagram and components, types of columns, stationary phases in GSC and
GLC, Detectors: TCD, FID, ECD
2.1.3 Qualitative, Quantitative analysis and applications
2.1.4 Comparison between GSC and GLC
2.2 Ion Exchange Chromatography (6 L)
2.2.1 Introduction, Principle.
2.2.2 Types of Ion Exchangers , Ideal properties of resin
2.2.3 Ion Exchange equilibria and mechanism, selectivity coefficient and separation factor, Factors
affecting separation of ions
2.2.4 Ion exchange capacity and its determination for cation and anion exchangers.
2.2.5 Applications of Ion Exchange Chromatography with reference to Preparation of demineralised
water, Separation of amino acids.

UNIT III:FOOD AND COSMETICS ANALYSIS

3.1 Introduction to food chemistry 10 L
3.1.1 Food processing and preservation:
Introduction, need, chemical methods, action of chemicals(sulphur dioxide, boric acid, sodium benzoate,
acetic acid, sodium chloride and sugar) and pH control Physical methods (Pasteurization and Irradiation)
3.1.2 Determination of boric acid by titrimetry and sodium benzoate by HPLC.
3.1.3 Study and analysis of food products and detection of adulterants
1) Milk: Composition & nutrients, types of milk (fat free, organic and lactose milk). Analysis of milk for
lactose by Lane Eynon’s Method

DEPARTMENT OF CHEMISTRY
2) Honey: Composition, Analysis of reducing sugars in honey by Coles Ferricyanide method
3) Tea: Composition, types (green tea and mixed tea), Analysis of Tannin by Lowenthal’s method
4) Coffee: Constituents and composition, Role of Chicory, Analysis of caffeine by Bailey Andrew
method.
3.2 Cosmetics (5 L)
3.2.1 Introduction and sensory properties
3.2.2 Study of cosmetic products –1) Face powder: Composition, Estimation of calcium and magnesium
by complexometric titration
2) Lipstick: Constituents, Ash analysis for water soluble salts: borates, carbonates and zinc oxide
3) Deodorants and Antiperspirants: Constituents, properties, Estimation of zinc by gravimetry.
UNIT IV:THERMAL METHODS AND ANALYTICAL METHOD VALIDATION
4.1 Thermal Methods 12 L
4.1.1 Introduction to various thermal methods (TGA, DTA and Thermometric titration)
4.1.2 Thermogravimetric Analysis (TGA), Instrumentation-block diagram, thermobalance (Basic
components: balance, furnace, temperature measurement and control, recorder) Thermogram (TG curve)
for CaC2O4.H2O and CuSO4.5H2O Factors affecting thermogram-Instrumental factors and Sample
characteristics. Applications:
i) Determination of drying and ignition temperature range
ii) Determination of percent composition of binary mixtures (Estimation of Calcium and Magnesium
oxalate)
4.1.3 Differential Thermal Analysis (DTA): Principle, Instrumentation, and Reference material used
Differential thermogram ( DTA curve) CaC2O4 .H2O and CuSO4.5H2O
Applications: Comparison between TGA and DTA.
4.1.4 Thermometric Titrations – Principle and Instrumentation
Thermometric titrations of :
1) HCl v/s NaOH
2) Boric acid v/s NaOH
3) Mixture of Ca+2 and Mg+2 v/s EDTA
4) Zn+2 with Disodium Tartarate.
4.2 Analytical Method Validation 03L
4.2.1 Introduction and need for validation of a method

DEPARTMENT OF CHEMISTRY
4.2.2 Validation Parameters: Specificity, Selectivity, Precision, Linearity, Accuracy and Robustness

References:
1. An Advance Dairy chemistry, V 3, P. F. Fox, P. L. H. Mc Sweeney Springer Unit/s (3.1,3.2)
2. Analysis of food and Beverages, George Charalanbous, Academic press 1978 Unit/s (3.1,3.2)
3. Analytical Chemistry of Open Learning(ACOL),James W. Dodd & Kenneth H. Tonge Unit/s (4.1,4.2)
4. Analytical chemistry David Harvey The ,McGraw Hill Companies, Inc. Unit/s (4.1,4.2)
5. Analytical Chemistry, Gary. D Christan, 5th edition Unit/s (2.1,2.2)
6. Analytical chemistry, R. K. Dave. Unit/s (2.1,2.2)
7. Chemical methods of separation, J A Dean, Van Nostrand Reinhold, 1969 Unit/s (2.1,2.2)
8. Egyankosh.ac.in/bitstream/123456789/43329/1/Unit-8 Unit/s (1.1,1.2,1.3)
9. Food Analysis, Edited by S. Suzanne Nielsen, Springer Unit/s (3.1,3.2)
10. Food Analysis: Theory and practice, Yeshajahu Pomeranz, Clifton E. Meloan, Springer Unit/s
(3.1,3.2)
11. Formulation and Function of cosmetics, Sa Jellineck Unit/s (3.1,3.2)
12. Fundamentals of Analytical Chemistry, D .A. Skoog and D. M. West and F. J. Holler Holt., Saunders
6th Edition (1992) Unit/s (2.1,2.2)
13. Government of India publications of food drug cosmetic act and rules. Unit/s (3.1,3.2)
14. Harry’s Cosmetology, Longman scientific co. Unit/s (3.1,3.2)
15. High Performance Thin Layer Chromatography in Food analysis, by Prem kumar, CBS Publisher and
distributer Unit/s (3.1,3.2)
16. Instrumental methods Of Analysis, by Willard Merritt Dean, 7thEdition, CBS Publisher and
distribution Pvt Ltd Unit/s (1.1,1.2,1.3) (4.1,4.2,4.3)
17. Introduction to Polarography and Allied Techniques, By Kamala Zutshi, New Age International,
2006. Unit/s (1.1,1.2,1.3)
18. Modern cosmetics, E. Thomessen Wiley Inter science Unit/s (3.1,3.2)
19. Principles of Instrumental Analysis , 5th Edition, By Skoog, Holler, Nieman Unit/s (4.1,4.2,4.3)
20. Principles of Polarography by Jaroslav Heyrovský , Jaroslav Kůta, 1st Edition, Academic Press,
eBook ISBN: 978148326478 Unit/s (1.1,1.2,1.3)
21. Solvent extraction and ion exchange, J Marcus and A. S. Kertes Wiley INC 1969 Unit/s (2.1,2.2,)

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Applied Component: Drugs & Dyes

Program Code: 1S00146 Course Code: USACDD601

(As per the Credit Based Semester and Grading System with effect from the academic year 2018-19)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Learn about drug discovery, design and development.
CO2 Know the classification of Chemotherapeutic Agents.
CO3 Outline the synthesis and mode of action of various kinds of Chemotherapeutic Agents.
CO4 Know the use of nanoparticles in medicinal chemistry.
CO5 Classify dyes on the basis of chemical constitution.
CO6 Write the synthesis of some dye molecules.
CO7 Understand the health & environmental hazards of synthetic dyes and their remediation.
CO8 Learn the application of dyes other than textile industry.
CO9 Distinguish between dyes and pigments.
CO10 Know the future scope of dye industry.
UNIT – I (Drugs)
1 1.1 Drug Discovery, Design and Development (6L)
1.1.1 Discovery of a Lead compound: Screening, drug metabolism studies and clinical observation,
Lipinski’s rule of
1.1.2 Medicinal properties of compounds from Natural Sources: Anti-infective and anticancer properties
of Turmeric (Curcumin)
1.1.3 Development of drug: The Pharmacophore identification, modification of structure or functional
group, Structure activity relationship (Sulphonamides).
1.1.4 Structure modification to increase potency: Homologation, Chain branching and Extension of the

DEPARTMENT OF CHEMISTRY
structure.
1.1.5 Computer assisted drug design.
1.2 Drug Metabolism: Introduction, Absorption, Distribution, Bio-transformation, Excretion Different
types of chemical transformation of drugs with specific examples. (3L)
1.3 Chemotherapeutic Agents: Study of the following chemotherapeutic agents with respect to their
chemical structure, chemical class, therapeutic uses, side effects and introduction to MDR wherever
applicable.
1.3.1 Antibiotics and antivirals: (2L)
Definition,
illin (β- lactum antibiotics)

– Trifluro -1-nitrobenzene)

1.3.2 Antimalarials: (2L)

Types of malaria; Symptoms; Pathological detection during window period (Life cycle of the parasites
not to be discussed)
-Amino quinolones)

Following combination to be discussed: Atremether-Lumefantrine (no structure)

1.3.3 Anthelmintics and AntiFungal agents (2L)
Drugs effective in the treatment of Nematodes and Cestodes infestations.

- Nitroaniline)

(Synthesis from 1- Bromo – 2,4-difluorobenzene)

UNIT – II (Drugs) Chemotherapeutic Agents continued.
2 2.1 Antiamoebic Drugs (1L)
Types of Amoebiasis
, Synthesis of Metronidazole from glyoxal by Debus
Radziszewski imidazole synthesis route. Following combination therapy to be discussed: Ciprofloxacin

DEPARTMENT OF CHEMISTRY
Tinidazole
2.2 Antitubercular and Antileprotic Drugs (3L)
Types of Tuberculosis; Symptoms and diagnosis of Tuberculosis.
Types of Leprosy.
General idea of Antibiotics used in their treatment.

- Nitropropane)
- Chloronitrobenzene)
Clofazimine (Phenazines)

Following combination therapy to be discussed:

(i) Rifampin + Ethambutol + Pyrazinamide
(ii) Rifampin + Isoniazide + Pyrazinamide
2.3 Anti-Neoplastic Drugs (2L)
Idea of malignancy; Causes of cancer
Brief idea of Immuno Stimulants &Immuno depressants

-bis (bromomethyl) toluene)

)
2.4 Anti-HIV Drugs (1L)
Idea of HIV pathogenicity, Symptoms of AIDS

2.5 Drug Intermediates: Synthesis and uses (2L)

1. 2,3,6-Triamino-6- hydroxypyrimidine from Guanidine
2.p-[2’-(5-Chloro-2-methoxy benzamido) ethyl]-benzenesulphonamide from Methyl-5-chloro-2-
methoxybenzene
3. 3-(p-Chlorophenyl)-3- hydroxypiperidine from 3-Chloroacetophenone
4. p-Acetyl amino benzenesulphonyl chloride from Aniline

DEPARTMENT OF CHEMISTRY
5. Epichlorohydrine from propene
2.6 Nano particles in Medicinal Chemistry (4L)
Introduction; Carbon nano particles (structures) and Carbon nano tubes:

-physical treatment.
Gold nano particles in treatment of: Cancer; Parkinsonism; Alzheimer.
Silver nano particles: Antimicrobial activity.
2.7 Drugs and Environmental Aspects (2L)
-industry on environment,
rence to: “The Nuremberg Code” and
“The Helsinki Declaration”
Unit – III (Dyes)
3.1 Classification of Dyes based on Chemical Constitution and Synthesis of Selected Dyes (Synthesis
of the dyes marked with * is expected) (12L)
i)Nitro Dye: Naphthol Yellow S
ii) Nitroso Dye: Gambine Y
iii)Azo dyes:
a) Monoazo dyes: Orange IV *(from sulphanilic acid) & Eriochrome Black T* (from β- naphthol)
b) Bisazo dyes: Congo Red* (from nitrobenzene)
c) Trisazo Dye: Direct Deep Black EW* (from benzidine)
iv)Diphenylmethane dye: Auramine O* (from N,N-dimethyl aniline)
v)Triphenylmethane dye:
a) Diamine series: Malachite Green* (from benzaldehyde)
b) Triamine series: Acid Magenta
c) Phenol series: Rosolic acid
vi) Heterocyclic Dyes:
a) Thiazine dyes: Methylene Blue
b) Azine dyes: Safranin T* (from o-toluidine)
c) Xanthene Dyes: Eosin* (from phthalic anhydride)

DEPARTMENT OF CHEMISTRY
d) Oxazine Dyes: Capri Blue
e) Acridine Dyes: Acriflavine
vii)Quinone Dyes:
a) Naphthaquinone: Naphthazarin
b) Anthraquinone Dyes: Indanthrene Blue* (from anthraquinone)
viii) Indigoid Dyes: Indigo* (from aniline + monochloroacetic acid)
ix) Phthalocyanine Dyes: Monastral Fast Blue B
3.2 Health and Environmental Hazards of Synthetic Dyes and their Remediation Processes (3L)
3.2.1 Impact of the textile and leather dye Industry on the environment with special emphasis on water
pollution
3.2.2 Health Hazards: Toxicity of dyes w.r.t food colours.
3.2.3 Effluent Treatment Strategies: Brief introduction to effluent treatment plants (ETP), Primary
Remediation processes: (Physical Processes) Sedimentation, Aeration, Sorption (activated charcoal, fly
ash etc.) Secondary Remediation processes: Biological Remediation –Biosorption, bioremediation and
biodegradation, Chemical Remediation: Oxidation Processes (chlorination), Coagulation-flocculation-
Precipitation.
Unit – IV (Dyes)
4.1 Non-textile uses of dyes: (8L)
4.1.1 Biomedical uses of dyes
i) Dyes used in formulations (Tablets, capsules, syrups etc) Indigo carmine, Sunset yellow, Tartrazine
ii) Biological staining agents Methylene blue, Crystal violet and Safranine T
iii) DNA markers Bromophenol blue, Orange G, Cresol red
iv) Dyes as therapeutics Mercurochrome, Acriflavine, Crystal Violet, Prontosil
4.1.2 Dyes used in food and cosmetics:
i) Properties of dyes used in food and cosmetics
ii) Introduction to FDA and FSSAI
iii) Commonly used food colours and their limits
4.1.3 Paper and leather dyes
i) Structural features of paper and leather
ii) Dyes applicable to paper and leather
4.1.4 Miscellaneous dyes

DEPARTMENT OF CHEMISTRY
i) Hair dyes
ii) Laser dyes
iii) Indicators
iv) Security inks
iv) Coloured smokes and camouflage colours
4.2 Pigments (3L)
Definition of pigments, examples, properties of pigments, difference between dyes and pigments.
Definition of Lakes and Toners
4.3 Dyestuff Industry - Indian Perspective (4L)
4.3.1 Growth and development of the Indian Dyestuff Industry
4.3.2 Strengths, Weaknesses, Opportunities and Challenges of the Dyestuff industry in India
4.3.3 Make in India - Future Prospects of the Dye Industry
Reference Books (For Units I & II):
1. Foye's principles of medicinal chemistry. 6th Edition, Edited by Davis William & Thomas
Lemke, Indian edition by B I Publication Pvt Ltd, Lippmcolt Williams & Wilkins.
2. Text book of organic medicinal & pharmaceutical chemistry. Wilson & Gisovolds, 11th Edition by
John H Block, John M Beale Jr.
3. Medicinal chemistry. Ashutosh Kar, New Age International Pvt. Ltd Publisher. 4th edition.
4. Burger’s Medicinal Chemistry, Drug Discovery & Development. Abraham & Rotella. Wiley
5. Medicinal chemistry. Ashutosh Kar, New Age International Pvt. Ltd Publisher. 4th edition.
6. Medicinal chemistry. V.K. Ahluwalia and Madhu Chopra, CRC Press.
7. Principle of medicinal chemistry. Vol 1 & 2 S. S. Kadam, K. R. Mahadik, K. G. Bothara
8. The Art of Drug synthesis. Johnson and Li. Wiley, 2007.
9. The organic chemistry of drug design & drug action. 2nd ed. By Richard B Silvermann, Academic
Press.
10. The Organic Chemistry of Drug Synthesis. Lednicer and Mitsher, Wliey.
11. Text book of drug design and discovery. Povl-Krog-Sgaard-Larsen, Tommy Liljefors and ULF
Madsen, 3rd Edition Taylor & Francis.
12. Bio-applications of nanoparticles. Edited by Warren C.W. Chan, Springer Publication.
13. Nanoparticle and technology for drug delivery (Drugs and pharmaceutical sciences). Ram B. Gupta &
Uday B.Kompella Pub. Informa Healthcare.

DEPARTMENT OF CHEMISTRY
14. Nano forms of carbon and its applications. Edited by Maheshwar Sharon and Madhuri Sharon. Monad
Nanotech Pvt. Ltd.
15. Environmental Chemistry. A. K. De
16. Text Book on Law and Medicine. Chokhani and Ghormade. 2nd Edition. Hind Law House,Pune.
17. Essentials of Medical Pharmacology. K D Tripathi, Jaypee Brothers Medical publishers Pvt. ltd.
Practical organic chemistry, Vogel.
References (For Units III & IV)
1. Chemistry of Synthetic Dyes, Vol I – IV, Venkatraman K., Academic Press 1972
2. The Chemistry of Synthetic Dyes and Pigments, Lubs H.A., Robert E Krieger Publishing Company,
NY ,1995
3. Chemistry of Dyes and Principles of Dyeing, Shenai V.A., Sevak Publications, 1973
4. Environmental Studies, Joseph Benny, Tata McGraw Hill Education, 2005
5. Fundamental Concepts of Environmental Chemistry,Sodhi. G. S., Alpha Science International, 2009
6. Planning Commission, Niti Aayog, FSSAI and FDA websites
7. Green Chemistry for Dyes Removal from Waste Water- Research Trends and Applications, Ed. Sharma
S.K., Wiley, 2015
8. Environmental Pollution- Monitoring and Control, Khopkar S.M., New Age International (P) Ltd, New
Delhi, 1982

DEPARTMENT OF CHEMISTRY
 Scheme of Examination
Semester End Theory Examinations:

There will be a Semester-end external Theory examination of 100 marks for each of the courses
USCH601, USCH602, USCH603, USCH604 and USACDD601 of Semester VI to be conducted
by the University.

1. Duration: The examinations shall be of 3 Hours duration.

2. Theory Question Paper Pattern:
a) There shall be FIVE questions. The first four questions Q.1, Q.2. Q.3, Q.4 shall be of
20 marks, each based on the units I, II, III & IV respectively. The fifth question Q.5 shall
be of objective type for 20 marks based on the entire syllabus consisting of multiple
choice questions, match the following, true/false etc.
b) All the questions shall be compulsory. The questions Q.1, Q.2, Q.3, Q. 4 shall have
internal choices within the questions. Including the choices, the marks for each question
shall be 30.
c) The questions Q.1, Q.2, Q.3, Q.4 may be subdivided into sub-questions as A, B, C, D,
E & F.
E & F.

QUESTION PAPER PATTERN:

Q. 1 Attempt any four from A/B/C/D/E/F Unit I Marks 20

Q. 2 Attempt any four from A/B/C/D/E/F Unit II Marks 20

Q. 3 Attempt any four from A/B/C/D/E/F Unit III Marks 20

Q. 4 Attempt any four from A/B/C/D/E/F Unit IV Marks 20

Q.5 Based On Unit I, II, III & IV.

(A) Select the correct option and complete the following sentences. (Any five) 05

(B) State whether the following statements are true or false. (Any five) 05

(C) State true or false. (Attempt any five) 05

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Physical Chemistry Practical

Program Code: 1S00146 Course Code: USCHP02

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Learn construction, principle & working of Ostawald’s viscometer.
CO2 Determine molecular weight of polymer using Ostawald’s viscometer
CO3 Understand the use of potentiometer for calculating number of electrons in redox reactions
CO4 Find out order of reaction by plotting graph.
CO5 Determine the amount of the substance in a given mixture by using conductometric titrations
CO6 find out the amount of given metal ion in a complex by using the static method.
CO7 Communicate the results of their experiments primarily via written laboratory report.

Non-Instrumental
Chemical Kinetics
1. To interpret the order of reaction graphically from the given experimental data and calculate the
specific rate constant. (No fractional order)
2. Viscosity
To determine the molecular weight of high polymer polyvinyl alcohol (PVA) by viscosity measurement.
Instrumental
Potentiometry
1. To determine the amount of iodide, bromide and chloride in the mixture by potentiometric titration
with silver nitrate.
2. To determine the number of electrons in the redox reaction between ferrous ammonium sulphate and
cerric sulphate potentiometrically.

DEPARTMENT OF CHEMISTRY
Conductometry
1. To titrate a mixture of weak acid and strong acid against strong base and estimate the amount of each
acid in the mixture conductometrically.
Colorimetry
1. To estimate the amount of Fe (III) in the complex formation with salicylic acid by Static Method.
References:
1. Practical Physical Chemistry 3rd edition A. M. James and F.E. Prichard , Longman publication
2. Experiments in Physical Chemistry R.C. Das and B. Behra, Tata Mc Graw Hill
3. Advanced Practical Physical Chemistry J. B. Yadav, Goel Publishing House
4. Advanced Experimental Chemistry. Vol-I J. N. Gurtu and R Kapoor, S. Chand and Co.
5. Experimental Physical Chemistry By V. D. Athawale.
6. Senior Practical Physical Chemistry By: B. D. Khosla, V. C. Garg and A. Gulati, R Chand and Co.
2011

: Question Paper Pattern :

Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform given Instrumental or Non-instrumental experiment and tabulate the result as per guidelines.
40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
Detailed scheme of marking of Experiment.

(5) Technique : 04 marks

Instrumental
(6) Reading : 14 marks
Or
(7) Graph & Calculations : 12 marks
Non-instrumental
(8) Accuracy : 10 marks
Experiment
Total marks : 40 marks

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Inorganic Chemistry Practical

Program Code: 1S00146 Course Code: USCHP06

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Understand key concepts of inorganic synthesis, reaction chemistry, and structure and bonding.
CO2 Assign IUPAC names to the inorganic complexes.
CO3 Determine the percentage purity of water soluble salt.
CO4 Perform qualitative analysis of cation or anion by only wet test method.

I. Inorganic preparations
1. Preparation of Tris (acetylacetonato) iron(III)
2. Green synthesis of bis (dimethylglyoximato) nickel (II) complex using nickel carbonate and sodium
salt of dmg.
3. Preparation of potassium trioxalato aluminate (III)
II. Determination of percentage purity of the given water soluble salt and qualitative detection w.r.t added
cation and/or anion (qualitative analysis only by wet tests). (Any three salts of main group metal ions)
Reference Books (practicals)
1. Vogel Textbook of Quantitative Chemical Analysis G.H. Jeffery, J. Basset.
2. Advanced experiments in Inorganic Chemistry., G. N. Mukherjee., 1st Edn, 2010., U. N. Dhur & Sons
Pvt Ltd .
3. Vogel's. Textbook of. Macro and Semimicro qualitative inorganic analysis. Fifth edition.

DEPARTMENT OF CHEMISTRY
 : Question Paper Pattern :
Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform a) Given preparation of inorganic complex and
b) Perform given volumetric analysis.

No. Exercise Marks

1. Inorganic preparation 20
2. Volumetric analysis 20
3. Vivo-voce 05
4. Journal 05
Total 50

 Detailed Marking Scheme for Inorganic Preparation

Errors (mL) Marks

8 12
 10 10
 15 08
 18 06
Above  18 00
Quality of product 04
Calculation 04
Total 20

 Detailed Marking Scheme for Volumetric analysis

Errors (mL) Marks

 0.2 12
 0.3 10
 0.4 08
 0.5 06
 0.6 and above 00
Calculation 04
Systematic work 04
Total 20

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Organic Chemistry Practical

Program Code: 1S00146 Course Code: USCHP10

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Identify physical type binary mixture (solid + liquid or liquid + liquid)
CO2 Separate solid-liquid & volatile liquid-non-volatile liquid mixture.
CO3 Learn to perform fractional distillation technique to separate volatile component.
CO4 Determine the purity, and percent yield of components.
CO5 Analyse and identify the solid or liquid organic compound by systematic qualitative microscale
technique.
CO6 Determine the purity, and percent yield of components.
CO7 Summarize findings in writing in a clear and concise manner.

References:
1. Practical organic chemistry – A. I. Vogel
2. Practical organic chemistry – H. Middleton.
3. Practical organic chemistry – O. P. Aggarwal.

DEPARTMENT OF CHEMISTRY
 : Question Paper Pattern :
Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform a) Separation of given solid + volatile liquid or volatile liquid + Non-volatile liquid organic
Mixture and find out its type.
b) Perform organic qualitative analysis of given organic compound.

No. Exercise Marks

1. Separation of binary mixture 20
2. Qualitative analysis of given organic compound 20
3. Vivo-voce 05
4. Journal 05
Total 50

Detailed Marking Scheme:

Chemical Type 04
Yield 08
Quality 04
Preliminary test 03
Elements 04
Functional Group 04
Melting point 04
Confirmatory Test 02
Name & structure 02
Technique & 05
systematic work
Journal 05
Viva-voce 05
Total 50

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Analytical Chemistry Practical

Program Code: 1S00146 Course Code: USCHP14

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : VI

Course Outcomes:
Upon completion of this course the students will be able to:
CO1 Handle and understand principles of different instruments such as colorimeter, spectrophotometer,
pH meter, flame photometer and turbidimeter
CO2 Find out the concentration of phosphoric acid in different soft drinks using pH meter.
CO3 Use spectrophotometer to estimate chromium in water sample.
CO4 Learn to perform ion-exchange chromatography for estimation of charged ions.
CO5 Handle potentiometer to find out acetic acid in vinegar sample.
CO6 Skill to plot the graph for obtaining result.
CO7 Aware about reporting of laboratory observation in scientific manner.
1 Estimation of Chromium in water sample spectrophotometrically by using Diphenyl carbazide.
2 Estimation of reducing sugar in honey by Willstatter method.
3 Estimation of Mg+2 & Zn+2 by anion exchange resin using an anion exchange resin

DEPARTMENT OF CHEMISTRY
4 Estimation of acetic acid in Vinegar sample by using Quinhydrone electrode potentiometrically.
5 Determination of phosphoric acid in cola sample pH metrically.
References:
1. Vogel’s Textbook of Quantitative Chemical Analysis, 5thEdn., G. H. Jeffery, J Bassett, J Memdham
and R C Denney, ELBS with Longmann (1989).
2. Vogel's Textbook of Quantitative Chemical analysis, Sixth edition, J. Mendham et.al
3. The chemical analysis of food and food products III edition Morris Jacob
4. The chemical analysis of food by David Pearson and Henry Edward

: Question Paper Pattern :

Maximum Marks: 50 Marks
Time: 3.5 Hours
Note: 1) Attempt all Questions
1. Perform given Instrumental or Non-instrumental experiment and tabulate the result as per guidelines.
40 marks
2. Viva-voce 05 marks
3. Journal 05 marks
Total 50 marks
Detailed scheme of marking of Instrumental Experiment.

Technique 04 marks
Observations 12 marks
Calculation 06 marks
Graph 06 marks
Accuracy 12 marks
Total 40 marks

Detailed scheme of marking of Non-Instrumental Experiment.

Observation 26
Reaction 02
Calculation 08
Systematic work 04
Total 40

DEPARTMENT OF CHEMISTRY
 S.P. Mandal’s
KANKAVLI COLLEGE,KANKAVLI
(Affiliated to University of Mumbai)
Syllabus

Programmme: B. Sc. Course: Chemistry

Drugs & Dyes Practical

Program Code: 1S00146 Course Code: USACDD6P1

(As per the Credit Based Semester and Grading System with effect from the academic year 2017-18)

Class: T. Y. B. Sc. Semester : VI

Upon completion of this course the students will be able to:

CO1 Learn to synthesis simple drug intermediate.
CO2 Synthesis and purification of drug molecule (Paracetamol)
CO3 Lab scale synthesis of dye molecules.
CO4 Develop skill of separation of a mixture of dyes.
CO5 Develop a skill of writing monograph of drug molecule according to I. P.

Syllabus-
I. Preparation
1. O-Methylation of β-naphthol.
2. Preparation of Paracetamol form p-aminophenol.
3. Preparation of Fluorescein
4. TLC of a mixture of dyes (safranine-T, Indigo carmine, methylene blue)
II] Preparation of monograph of any one drug from syllabus by I.P. method.
OR
Industrial visit Report.

References:
1. Vogel’s Textbook of Quantitative Chemical Analysis, 5th Edn., G. H. Jeffery, J Bassett, J Memdham
and R C Denney, ELBS with Longmann (1989).

DEPARTMENT OF CHEMISTRY
2. Vogel's Textbook of Quantitative Chemical analysis, Sixth edition, J. Mendham et.al
3. The chemical analysis of food and food products III edition Morris Jacob
4. The chemical analysis of food by David Pearson and Henry Edward

: Question Paper Pattern :

Maximum Marks: 100 Marks
Time: 3.5 Hours + 3.5 Hours
Note: 1) Attempt all Questions
Q. Perform given preparation of compound and estimation of sample solution.
Marking Scheme
1. Preparations 40 marks
2. Estimation 40 marks
3. Viva Voce 10 marks
4. Journal & Project 10 marks
Total 100 marks

DEPARTMENT OF CHEMISTRY