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Dissertation On Stem Cells

This document discusses the challenges of writing a dissertation on stem cell research, including conducting extensive research, analyzing complex data, and ensuring accuracy and originality. It notes that stem cell research is rapidly advancing but also controversial. Seeking professional help from experienced dissertation writers can help students complete their dissertation more easily and with less stress. Ordering dissertation writing assistance can save time, ensure quality, and provide personalized support and guidance throughout the writing process.
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100% found this document useful (2 votes)
105 views8 pages

Dissertation On Stem Cells

This document discusses the challenges of writing a dissertation on stem cell research, including conducting extensive research, analyzing complex data, and ensuring accuracy and originality. It notes that stem cell research is rapidly advancing but also controversial. Seeking professional help from experienced dissertation writers can help students complete their dissertation more easily and with less stress. Ordering dissertation writing assistance can save time, ensure quality, and provide personalized support and guidance throughout the writing process.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Only significant human advances throughout the world have been made on adult stem cells.
Consequently, qualitative research is well-suited to explore the opinions of the clinicians and
researchers working in the field of embryonic stem cell research today in order to draw conclusions
on the current situation (Siedman, 2006). The use of infected lines in patient treatment could have
devastating effects. Stem Cell Bazaar. October 2007. Stem cell information. 25 May 2009. Weiss,
Rick. Scientists Find New Way Stem Cells Repair Organs. 08 October 2004. 26 May 2009. The
concept and subject of embryonic stem cell research has been an ongoing controversy by medics and
politicians in the United States for many years. T9RER1LvhI4 Bioethics, N. C. (n. d. ). Genetically
Modified Crops:The Ethical and Social Issues. It also sheds light on a controversy: are large cells or
small cells more likely to be cancer stem cells. With lack of imminent findings and insufficient
information on the potential therapeutic benefits of embryonic stem cell research, controversies on
viability of such studies have immediate impact on the work of scientists and researchers. Embryonic
stem cell research continues to provoke serious controversies. Examples stem cell treatments include:
Systemic injection of adipose-derived stem cells to help regenerate an organ or a tissue, including the
pancreas, the heart or the brain. Countries such as Germany and Italy allow research only on cell
lines before a certain date and countries such as Austria and Poland prohibit all stem cell research.
Unfortunately President Reagan did not support this board and their federally funded investigations
into the safety of using human embryos developed in vitro for less than 14 days and in 1980, he did
not renew the Ethics Advisory’s Board Charter. Most recently, stem cells have been found in the
amniotic fluid that surrounds a baby in the womb. In such a way, qualitative research weaknesses are
transformed into strengths, if the research is aimed at discovery of new knowledge (Yin, 2009).
Stem cell therapy has grown in popularity in recent years. For drug discovery and disease modeling,
researchers must be persistent and patient. “iPSCs can only shorten the discovery process, not skip it.
Severe heart damage and Parkinson’s disease benefits appear promising with adult stem cells.
Introduction Embryonic Stem Cell Technology is developing rapidly at present because of the huge
developments in genetic engineering. The closest human counterpart to that would be the idea that a
person comes from just two cells. Many embryonic stem cell lines are grown using mouse feeder
cells. Scientists have turned human pancreatic ductal cells into cells that produce insulin, providing
hope for diabetics. Because of this, 13 out of the 15 stem cell research companies in America work
on adult stem cells.These stem cells are superior for several reasons: 1) they do not involve the
destruction of the embryo, therefore sparking no ethical debate.2) they avoid the problem of
immunological rejectionand 3) they have a proven track record of success with human patients,
while embryonic stem cells do not. Embryonic Stem Cells: These are derived from a blastocyst,
which is a cluster of identical embryonic cells that forms when an egg cell is fertilized by a sperm
cell. However, no other research has triggered the same global concerns on ethical, political, medical,
and social issues. These cells are known to be pluripotent, which denotes the ability to transform into
any cell of the body, including gametes. Even with compatible major HLA loci, mismatches at minor
HLA loci can lead to graft versus host disease (GVHD), in which successfully grafted donor T
lymphocytes mount an immune response against host antigens, leading to excess inflammation and
immune response. For these reasons, HSCs represent an attractive target for regenerative medicine.
1.2. Stem Cells: Source for Potential Therapy The differentiation capacity of HSCs has been heavily
utilized in regenerative medicine and other stem cell-based therapies. In the event that participation
in this study causes any emotional distress, the participants will be provided a referral list for
therapeutic assistance. HSC, hematopoietic stem cell; HPC, hematopoietic progenitor cell; CMP,
common myeloid progenitor; CLP, common lymphoid progenitor. In its place, a systemic survey
research could have helped more.
However, there are many concerns surrounding this topic because the cells can be taken from
embryos, which would otherwise have been discarded or used in research on other topics. The walls
of the chamber are coated so that the cell can’t latch on. He has written about Catholicism for outlets
including Humanitas and Catholic Answers Magazine. A follow-up letter to each subject will
provide an explanation of the details of the interview format, the duration of the interview and
confirmation of confidentiality and anonymity. Note that from the first issue of 2016, this journal
uses article numbers instead of page numbers. Specifically, the generation of iPSC-derived
hematopoietic stem cells could theoretically solve all the issues connected with HLA compatibility
by eliminating complications associated with transplantation, such as the use of immunosuppressive
drugs, graft versus host disease, etc. Legislation surrounding stem cell research started in 1974,
where Congress implemented a ban on all federally funded fetal tissue research until there were
guidelines set up by the National Commission for the Protection of Human Subjects of Biomedical
and Behavioral Research. Artificial embryo twinning is done by separating the early embryo into two
cells and allowing the cell to divide and grow on its own. Journal of Functional Morphology and
Kinesiology (JFMK). Gene-corrected cells exhibited normal karyotypes and full pluripotency with no
off-targeting effects. The methods of data collection were described in detail, including how the
study population was recruited, and the information contained in the consent form. While the
researcher will establish the general direction of the conversation, the researcher will purse the topics
raised by the interviewee. Because of this, 13 out of the 15 stem cell research companies in America
work on adult stem cells.These stem cells are superior for several reasons: 1) they do not involve the
destruction of the embryo, therefore sparking no ethical debate.2) they avoid the problem of
immunological rejectionand 3) they have a proven track record of success with human patients, while
embryonic stem cells do not. It might seem farfetched now, but what if someone found out how.
Over in Europe, countries such as Spain, Sweden and the United Kingdom allow SCNT. All
statements and opinions are provided for educational and informational purposes only. The stem cell
news was published in the journal of Natural biotechnology. Donors must be presented with proper
documentation that they were aware of all options for the embryos. High-dose chemotherapy with
stem cell transplant is a treatment option that has been used for women with advanced metastatic. By
teaching students and aspiring researchers on stem cell research essentials, educators transmit their
views and beliefs to the audiences. Alternatively, HSCs can be harvested from more primitive and
“antigenically naive” umbilical cord blood donations. The greatest advances in stem-cell research so
far have come through adult stem-cell research: Dozens of therapeutic uses have been developed and
are currently in use. NIH Releases Guideline for Stem Cell Research, 2009) Regulations introduced
in various developed countries to ensure the ethical use of biomedical technology in addition to the
use of systems to detect emerging diseases are some of the ways the government agencies around the
world are trying to reduce the chance of having future biomedical catastrophies. Adult stem cells
already exist within a human being and can come from children or adults without harming the person
from various parts of the body, such as bone marrow. The hierarchy of stem cell potency during
embryonic to adult development. Stem cell therapy has grown in popularity in recent years. Some of
the concerns surrounding genetically modified organisms and the effects on an individual’s health.
The only problem with George Bush’s opposition was that he never banned the private and state
sectors from racticing this version of stem cell research. Little contribution has been made by the
researchers of University of Nevada to resolve this dispute. Visit our dedicated information section
to learn more about MDPI.
The interviews will be listened to a third time while cross- checking with the transcript to verify the
accuracy of the transcription. Thomson case. In May of 2001, Christopher Reeve (the actor) and
seven other scientists filed a federal lawsuit claiming the Bush administration withheld federal
funding for stem cell research illegally. Their application to repair or introduce disease-relevant
mutation in iPSCs could play a fundamental role in studying and understanding pluripotency biology.
What it did was change the intensity of my feeling. This differentiation problem is acknowledged on
the International Society for Stem Cell Research website. Nightlight Christian Adoptions (a non-
profit adoption agency) as well as others made claims that the guidelines violate the legislative ban
found that prohibits federal funding of research in which a human embryo is either destroyed or
discarded. The hierarchy of stem cell potency during embryonic to adult development. To address
this issue, Nakahata, Saito and other colleges established iPSCs from fibroblasts of six patients with
FA and FANCA mutations. Embryonic stem cell research is a relatively young direction in medical
research. In order to achieve the cells, they are to be taken while in the early forming of a human
embryo. NIH Releases Guideline for Stem Cell Research, 2009) Regulations introduced in various
developed countries to ensure the ethical use of biomedical technology in addition to the use of
systems to detect emerging diseases are some of the ways the government agencies around the world
are trying to reduce the chance of having future biomedical catastrophies. The phenomenon under
investigation is evolving because of changing political, social, and economic factors. Trustworthiness
is measured in credibility, transferability, dependability, and confirmability (Creswell, 1998). People
against the abortion are against it for secular and non-secular reasons. Treating autoimmune diseases
like multiple sclerosis or Crohn’s disease. Only significant human advances throughout the world
have been made on adult stem cells. As Yin (2011) emphasized, site selection should be purposeful.
Participants will be informed that the interview would be audio taped, and that the investigator
might also take notes during the course of the interview. In particular, great efforts have been
directed to the hematology field, leading to significant advances and offering new possibilities for
disease modeling, drug development and autologous cell therapy. For life to be possible, humans
obviously need blood, and there is no blood present in embryos at all. The team speculated they
might have found an important and easy accessible source of stem cells to repair damaged teeth,
induce bone regeneration and treat neural injury or diseases such as Alzheimer's or Parkinson's. For
more information on the journal statistics, click here. Mature leukocytes are released into the
bloodstream, where. If you are being treated for any medical illness, check with your medical
professional before starting any protocol. As mentioned above, California did pass a legislation
allowing a significant amount of money to fund stem cell research. Ideally, iPSCs can be used to
generate universal donor RBCs generated from antigenless blood type O individuals. However,
granulocytes are only rarely used, due to (1) their short half-life and (2) difficulties in procurement
and storage. Application of Induced Pluripotent Stem Cell Technology to the Study of
Hematological Diseases. In theory, these differentiated cells could be used to repair or replace
defective cells or tissues. By employing participants who personally experienced the phenomenon
authenticity will be obtained.
The need to make his daughter better motivated his studies. When put into practice, the technology
of stem cells would revolutionize the way of treatment and cure. (Maienschein)Patients would no
longer be dependent upon organ transplants and materials for their survival like the transplantation
of kidneys and bone marrow instead an injection of proper amount of classified stem cells would be
enough to create a new organ or to repair fatal damages like cancerous tumors inside the human
body. While these embryos are not created in the normal manner, the Church recognizes that they,
too, are alive, and their destruction is gravely immoral. They supply new cells to the growing body
and also replace damaged cells. Among those sciences, stem cell treatment is a widely known
procedure that is becoming commonly debatable across the United States. I believe we can also
stimulate our own production of these cells with proper nutritional interventions. These cells are
unspecialized cells characterized by their ability to develop into various different types of cells in the
body, for example. Their enactment as research tools, therefore, developed comparatively slowly. For
example, adult stem cells are often drawn from bone marrow, while umbilical-cord stem cells are
taken from the blood that remains in the umbilical cord after birth. Fifteen percent and less than that
did not find this beneficial. Additionally, each participant will be given a consent form to sign prior
to participation in the study describing the purpose of the study, potential risks and benefits,
confidentiality, and the right to discontinue participation in the study at any time. A mother would
not refer to the life within her as a bunch of living cells with no purpose or future. However, there
are many concerns surrounding this topic because the cells can be taken from embryos, which would
otherwise have been discarded or used in research on other topics. He has written about Catholicism
for outlets including Humanitas and Catholic Answers Magazine. The new cell which is formed by
the stem cell division has the ability to either become another stem cell or a cell with a particular
function. We use cookies to create the best experience for you. This may not produce the same
results as using stem cells from humans or monkeys, for example. Their participation will enable in
obtaining a critical insight into perceived barriers, myths, and cultural beliefs that prevent health
professionals from further research in clinical research environment. In other words, they can develop
into each of the more than 200 cell types of the adult body when given sufficient and necessary
stimulation for a specific cell type. However, the use of ESCs is hindered not only by limited access
to and low amounts of source material, but also by ethical concerns related to working with
embryonically-derived cells. They are forced to show genes that are pivotal for preserve the identity
of embryonic stem cells. Introduction. Stem cells refer to the cells which are capable of developing
into various cell types for example brain cells and muscle cells. Only cells from an earlier stage of the
embryo, known as the morula, are totipotent, able to become all tissues in the body and the
extraembryonic placenta. Journal of Manufacturing and Materials Processing (JMMP). These are
multipotent, meaning that they can become many other types of cells at the same time, including
bone marrow and fat tissue. These cells reproduce in their chambers, forming tiny floating colonies,
or tumorspheres. Looking into different countries stem cell research policies can be quite profound.
Age, gender, and other demographic characteristics will be included in the selection criteria since
they are very important for the purpose of this research. Not only can it open doors for many diseases
and illnesses, it is a very profitable area of study. This implies that education institutions should
organize retreats that will enable students learn more about Stem Cell Technology.
The interviews will be recorded via audiotape and will approximately take 30 to 90 minutes. The idea
of stem cell research is a gateway to new sciences. There are certain areas of Christianity that says all
human life is intended by God and with that being the basis of many chapters in the Bible, most
people are against abortion. When evaluating the Catholic Church's stance on stem-cell research,
there are important questions to ask. Editors select a small number of articles recently published in
the journal that they believe will be particularly. Environmental Issues (Jessica Moss) While stem cell
research is mainly used for the advancement of biomedical technology, curing diseases and mending
illnesses, there are people who believe stem cell research can be used for negative reasons. Severe
heart damage and Parkinson’s disease benefits appear promising with adult stem cells. In addition,
the invitation will be followed with a personal phone call to confirm agreement to participate and set
the date for the interview. Even with compatible major HLA loci, mismatches at minor HLA loci can
lead to graft versus host disease (GVHD), in which successfully grafted donor T lymphocytes mount
an immune response against host antigens, leading to excess inflammation and immune response.
Age, gender, and other demographic characteristics will be included in the selection criteria since
they are very important for the purpose of this research. Of these methods, the case study approach is
the most appropriate for this project. Stem Cell School This website is made more high school and
undergraduate life science educators to help them teach about stem cells. Adult stem-cell research is
more advanced and effective than research on embryonic stem cells. Additionally, red blood cells
and platelets are attractive iPSC-derived end products, given their anucleate nature and thus absence
of oncogenic risk. These peripheral blood stem cells, or PBSCs, can be used just like bone marrow
stem cells to treat leukemia, other cancers and various blood disorders. Embryonic, fetal and adult
stem cells or the most common stem cells used in the research. Throughout this time, he has been
met with much acclaim and is now the head of Emergency Medical Services in Nye County, Nevada.
The fetus must be approximately ten weeks of gestation. Feature papers are submitted upon
individual invitation or recommendation by the scientific editors and must receive. Scientists argue
only 50 of them would be needed to harvest more embryonic stem cells. So, here we are. Serving up
everything you need to know about them. Many embryonic stem cell lines are grown using mouse
feeder cells. To better understand the controversy surrounding abortion and stem cell research you
must look at both viewpoints: For and Against. In general, increasing cell specialization parallels a
decrease in potency. Fourth, each category will be studied to determine if they are linked by some
means. The epidermal stem cells give rise toat the base of hair follicles. While most blood stem cells
reside in the bone marrow, a small number are present in the bloodstream. Journal of Experimental
and Theoretical Analyses (JETA). This may make them potentially useful sources of transplant tissue
and cell-based therapies. These cells are unspecialized cells characterized by their ability to develop
into various different types of cells in the body, for example.
Obama did set up limitations to the embryonic cell research. Artificial embryo twinning is done by
separating the early embryo into two cells and allowing the cell to divide and grow on its own.
International Journal of Environmental Research and Public Health (IJERPH). The findings
suggested stem cells from baby teeth behave more like stem cells harvested from umbilical cord
blood, which is another early developmental source. It is much more likely embryos will be used for
research than transplant, such as the drug testing we carry out on animals and adults.However, the
real debate is not about whether we are compassionate towards embryos, nor is it about whether we
should seek to cure various diseases. Stem cell therapy has grown in popularity in recent years.
Journal of Manufacturing and Materials Processing (JMMP). Somatic cell nuclear transfer is done by
isolating a somatic cell, transferring the nucleus from the cell to an egg cell that has already had its
nucleus removed. A mother would not refer to the life within her as a bunch of living cells with no
purpose or future. Recently, there has been an increase in the number of “injection centers” around
the country offering alternative injections including viscosupplementation, platelet-rich protein
(PRP) and stem cell therapy. Upon its discovery, scientists became very enthusiastic in pursuing stem
cell researches most especially because it shows potentials for treating several diseases. They form the
basis for growth and repair throughout our lives. Stem cells are non-specialized cells, which has the
potential to generate a particular cell in the body. In particular, great efforts have been directed to the
hematology field, leading to significant advances and offering new possibilities for disease modeling,
drug development and autologous cell therapy. The phenomenon under investigation is evolving
because of changing political, social, and economic factors. Embryonic stem cell research continues
to provoke serious controversies. Given that the majority of disease-relevant mutations are restricted
to hematopoietic lineages, the traditional iPSC generation from fibroblasts may lack the genetic
information implicated in the disease development. The team speculated they might have found an
important and easy accessible source of stem cells to repair damaged teeth, induce bone regeneration
and treat neural injury or diseases such as Alzheimer's or Parkinson's. This procedure paved the way
for transplanting organs, reducing the possibility of rejection within the body, without the use of
anti-rejection drugs. Many countries use their power negative such as North Korea and their threats
using the weapons of mass destruction. Introduction (Background Information) (Jessica Moss) There
are many emerging technologies that are facing struggles against new improvements every day.
International Journal of Translational Medicine (IJTM). ES cells are pluripotent and give rise during
development to all derivatives of the three primary germ layers: ectoderm, endoderm and mesoderm.
The current debate over embryonic stem cell research raises a new ethical dilemma, with any solution
or compromise to the issue being equivocal at best. It is clear that the stem cell plays a crucial role in
supporting the body function not only under normal conditions but during an external attack in the
form of disease or injury. This study will also utilize peer and dissertation committee review to
ensure the accuracy and authenticity of the findings. It is difficult to tell whether this is truly a
reparative process versus just the effects of the MSCs’ anti-inflammatory properties. Scientists are
exploring new uses for these stem cells that go beyond diseases of the blood. People also are afraid
of the idea of cloning and genetically modified food. This study, titled “Scaling and automation of a
high-throughput single-cell-derived tumor sphere assay chip,” is published in the journal Lab on a
Chip.
Silverman, D. (2004). Qualitative research: theory, method and practice. Thousand Oaks, CA: SAGE.
Drisko, J.W. (2008). How is qualitative research taught at the master’s level. The disbanding of the
EAB halted federal funding of human embryo research. Transplant to Cure LeukemiaTransplant to
Cure Leukemia. Uncertain therapeutic application of embryonic stem cell research findings is another
limiting factor. Consequently, qualitative research is well-suited to explore the opinions of the
clinicians and researchers working in the field of embryonic stem cell research today in order to draw
conclusions on the current situation (Siedman, 2006). Individuals have different opinions regarding
this technology. He has written about Catholicism for outlets including Humanitas and Catholic
Answers Magazine. These are multipotent, meaning that they can become many other types of cells
at the same time, including bone marrow and fat tissue. To address this issue, Nakahata, Saito and
other colleges established iPSCs from fibroblasts of six patients with FA and FANCA mutations.
Uses of stem cell In therapy: degenerative diseases are the consequence of cellular loss or loss of
cellular function. This was a major breakthrough not only in the legislation aspect of stem cell
research but also by showing that people supported this idea. Due to the complexity of the stem cell
research and lack of proper forum for debating its outcomes, it is expected that the general public has
a hazy opinion about this research. Demographic data will be collected prior to starting the interview.
For more information on the journal statistics, click here. Unfortunately, transplantation of iPSC-
derived blood cells suffers from major limitations concerning cell maturation and low yields.
Developed at the University of Michigan the technique could help researchers better understand so-
called cancer stem cells. Many countries use their power negative such as North Korea and their
threats using the weapons of mass destruction. Leukemia is a disfunction of the bone marrow stem
that over produces white. This group of participants is also affected by bioethical issues surrounding
stem cell research. At times, the body’s own ability to repair is not sufficient and the process of
cellular loss leads to the development of a disease. We use cookies on our website to ensure you get
the best experience. Adult stem cells are multipotent, lineage-restricted cells, and are capable of
generating a single germ layer, often of a single organ system. Journal of Functional Morphology and
Kinesiology (JFMK). What the debate is about it what source of stem cells is preferred. Thick
description is necessary to ensure that the findings are transferable between the researcher and those
being studied (Creswell, 1998). Reflective listening, clarification, and prompting skills will be
utilized as needed to facilitate the discussion. Cancer cells are not all the same, and one theory holds
that no more than 5 percent of the cells in a tumor are cancer stem cells. Chawla turned the book into
a movie to get the message out there. There are actually many different types of stem cells that can be
used to help diseased people.

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