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Reasoning Biochemistry

This document contains biochemistry questions from past years organized by topic and year. The questions cover a range of topics including enzyme function, metabolic pathways, vitamin and mineral functions, genetic coding, and diseases. Specifically, the document includes 3-mark short answer questions from 2020 on topics like the Cori cycle, HMP shunt, transamination, and phenylketonuria. It also contains 2-mark questions from 2019 on dietary fiber, glycemic index, vitamin K function, scurvy biochemistry, zinc and copper functions, xenobiotic metabolism, tumor suppressor genes, apoptosis, and genetic code degeneracy.

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Karan Soni
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66 views5 pages

Reasoning Biochemistry

This document contains biochemistry questions from past years organized by topic and year. The questions cover a range of topics including enzyme function, metabolic pathways, vitamin and mineral functions, genetic coding, and diseases. Specifically, the document includes 3-mark short answer questions from 2020 on topics like the Cori cycle, HMP shunt, transamination, and phenylketonuria. It also contains 2-mark questions from 2019 on dietary fiber, glycemic index, vitamin K function, scurvy biochemistry, zinc and copper functions, xenobiotic metabolism, tumor suppressor genes, apoptosis, and genetic code degeneracy.

Uploaded by

Karan Soni
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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BIOCHEMISTRY REASONING MADE BY – KESHAV(67)

**Batch 2021 – Part A:**

1. Administration of ethanol in treatment of methanol poisoning.


2. Oral rehydration solution in diarrhea.
3. Cause of death in carbon monoxide poisoning.
4. Denaturation of proteins.
5. Mitochondria are the powerhouse of the cell.
6. Liver plays an important role in blood glucose regulation.
7. NSAIDs (Non-Steroidal anti-inflammatory drug) as analgesics.
8. HbA1c as an indicator of glycemic control in diabetes mellitus.
9. Neonatal screening and early intervention in phenylketonuria.
10. Lactulose administration in hepatic encephalopathy.
11. Xanthine oxidase as a suicidal enzyme.
12. Therapeutic use of enzyme in myocardial infarction.
13. Enzymes useful in the diagnosis of AMI.
14. Cause of death in cyanide poisoning.
15. Cholesterol and membrane fluidity.
16. Hyperuricemia in von Gierke’s disease.
17. Primaquine causes hemolytic anemia in G6PD deficiency.
18. Yoghurt is easier to digest than milk.
19. Accumulation of phytanic acid in Refsum’s disease.
20. Darkening of urine on standing in alkaptonuria.
**Batch 2020:**

1. Enzymes are used for the diagnosis of several diseases.


2. Essential fatty acids cannot be synthesized by the human body.
3. Detergent action of bile salts in emulsification of lipids in the small
intestine.
4. Lysosomal enzymes are responsible for maintaining the cellular
compounds in a dynamic stage.
5. Many amino acids give rise to specialized products in the human body.
6. The rationale of storing glycogen in the muscles.
7. Pyruvate dehydrogenase complex.
8. How ammonia is transported in the blood.
9. How heme is synthesized in our body.
10. Uncouplers of oxidative phosphorylation.
11. Activity of the enzyme is markedly affected by several factors.
12. Mitochondria are the powerhouse of the cell.
13. Mucopolysaccharides are essential components of tissues.
14. Consuming trans fats increases the risk of cardiovascular disease.
15. Creatine kinase (CK) exists in three isoenzyme forms.

**Batch 2019 Part A missing**

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**Batch 2021 – Part B:**

2
1. Vitamin A deficiency can cause night blindness.
2. Kidneys have an important role in the regulation of pH in ECF.
3. Deficiency of vitamin B12 results in megaloblastic anemia.
4. Vitamin E as an antioxidant.
5. Diabetic patients should avoid foods with a high glycemic index.
6. Oxidation of drugs by cytochrome P450.
7. Telomerase and aging.
8. Impact of proto-oncogene mutation.
9. MAO (Monoamine oxidase) inhibitors as drugs.
10. Phototherapy in neonatal jaundice.
11. Tryptophan deficiency can cause pellagra.
12. Diabetic ketoacidosis can lead to high anion gap and metabolic
acidosis.
13. Folic acid supplementation during pregnancy can prevent neural tube
defects (NTD).
14. Chronic renal failure can cause hypocalcemia.
15. Hyperventilation can lead to respiratory alkalosis.
16. Not all genes are subject to gene regulation.
17. “Lemon-on-stick” appearance in Cushing’s syndrome.
18. p53, the guardian of the genome.
19. Hyperpigmentation in Addison’s disease.
20. Clinical manifestations of xeroderma pigmentosum.

**Batch 2020:**

1. Biochemical basis of manifestations of rickets.


2. Tryptophan deficiency causes pellagra.

3
3. Selenium as an antioxidant.
4. Hyperventilation in chronic lung obstruction disorder.
5. Requirement of thiamine is increased in alcoholics.
6. Clay-colored stool in jaundice.
7. Glutathione in detoxification of xenobiotics.
8. One tRNA can recognize more than one codon for a specific amino
acid.
9. Cancer is a result of an imbalance between apoptotic and antiapoptotic
systems.
10. Mechanism of action of chloramphenicol in translation.
11. Biochemical basis of clinical manifestations of scurvy.
12. High fiber diet reduces the risk of coronary heart disease.
13. A single intramuscular dose of vitamin K is given to all newborns.
14. Arterial blood gas changes in case of metabolic acidosis.
15. Biochemically, the custom of eating dal (pulses) with rice (cereal) is
beneficial.
16. Role of telomerase in cancer.
17. Mechanism of action of tetracycline in translation.
18. High-colored urine in jaundice.
19. Genetic code is (nearly) universal.
20. Xeroderma pigmentosa.

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**Briefly 3 Marks ** New pattern considered in 2 Marks**

** Batch 2020 Part A **

4
1. Cori cycle.
2. Importance of HMP shunt.
3. Transamination reaction.
4. Importance of cholesterol in our body.
5. Phenylketonuria.

**Batch 2019: Part B**

6. Role of dietary fibers in the prevention of obesity and disease.


7. Why low glycemic index foods are good for health?
8. Anticoagulant role of Vitamin K.
9. Biochemical basis of scurvy.
10. Biochemical functions of Zinc and Copper.
11. Purpose of two phases of metabolism of Xenobiotics.
12. How tumor suppressor genes affect the cell cycle?
13. Apoptosis and cancer.
14. Degeneracy of genetic code.
15. Alterations in urine specific gravity & urine osmolarity in Addison’s
disease.

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