Alzheimer's disease is a brain disorder that causes memory loss and cognitive decline. It is the most common cause of dementia. The disease is named after Dr. Alois Alzheimer, who first identified characteristic amyloid plaques and tau tangles in the brain tissue of a woman who had died of an unusual mental illness. Risk factors include increasing age, cardiovascular and metabolic conditions, genetics, lifestyle factors, and Down syndrome. The disease progresses through mild, moderate, and severe stages, destroying memory and cognitive abilities. While there is no cure, certain medications and therapies can temporarily manage symptoms.
Alzheimer's disease is a brain disorder that causes memory loss and cognitive decline. It is the most common cause of dementia. The disease is named after Dr. Alois Alzheimer, who first identified characteristic amyloid plaques and tau tangles in the brain tissue of a woman who had died of an unusual mental illness. Risk factors include increasing age, cardiovascular and metabolic conditions, genetics, lifestyle factors, and Down syndrome. The disease progresses through mild, moderate, and severe stages, destroying memory and cognitive abilities. While there is no cure, certain medications and therapies can temporarily manage symptoms.
Alzheimer's disease is a brain disorder that causes memory loss and cognitive decline. It is the most common cause of dementia. The disease is named after Dr. Alois Alzheimer, who first identified characteristic amyloid plaques and tau tangles in the brain tissue of a woman who had died of an unusual mental illness. Risk factors include increasing age, cardiovascular and metabolic conditions, genetics, lifestyle factors, and Down syndrome. The disease progresses through mild, moderate, and severe stages, destroying memory and cognitive abilities. While there is no cure, certain medications and therapies can temporarily manage symptoms.
Alzheimer's disease is a brain disorder that causes memory loss and cognitive decline. It is the most common cause of dementia. The disease is named after Dr. Alois Alzheimer, who first identified characteristic amyloid plaques and tau tangles in the brain tissue of a woman who had died of an unusual mental illness. Risk factors include increasing age, cardiovascular and metabolic conditions, genetics, lifestyle factors, and Down syndrome. The disease progresses through mild, moderate, and severe stages, destroying memory and cognitive abilities. While there is no cure, certain medications and therapies can temporarily manage symptoms.
Factors AccordingtoCDCCentersforDiseaseControlandPrevention,thefollowingare nown about Alzheimer's disease: k ● Age ● Cardiovascular, high BP and high cholesterol ● Diabetes ● Smoking ● Obesity ● Depression ● Head injury Vascular contribution
Types of Alzheimer’s Disease
There are two types of Alzheimer’s disease: ● Late-onset type in whichsymptomsappear in the mid-60s ● Early-onset typeinwhichthesymptomsappearbetweentheageof30to60 years
ltimately,plaquesandtanglesspreadthroughoutthebrain,andbraintissueshrinks U significantly. People with severe Alzheimer’s cannot communicate and are completelydependentonothersfortheircare.Neartheendoflife,thepersonmay be in bed most or all of the time as the body shuts down.
T Researchers are testing some of these possibilities in clinical trials. Tau protein tangles esearchers believe that with Alzheimer’s, abnormal tau builds up in the neuron, R causing the microtubules to tangle. This prevents nutrients and other essential supplies from moving through the cell and it dies. Your vascular system fails to provide enough blood and nutrients to the brain ● The brain lacks the glucose needed to provide enough energy for the brain’s activities ● Chronic inflammation sets in as the debris is not cleared properly from around the neurons Eventually, the neurons can’t communicate and they die, and the brain begins to shrink.
Amyloid plaques oxic protein deposits that form in the brains of people living with Alzheimer's T disease most likely leak into the brain from fat carrying particles in blood, called lipoproteins. "This 'blood-to-brainpathway'issignificantbecauseifwecanmanage thelevelsinbloodoflipoprotein-amyloidandpreventtheirleakageintothebrain,this opensuppotentialnewtreatmentstopreventAlzheimer'sdiseaseandslowmemory loss." "While further studies are now needed, this finding shows the abundance of these toxic protein deposits in the blood could potentially be addressed amyloid, therefore reducing their risk or slowing the progression of Alzheimer's disease. hat's the relationship between diabetes W and dementia? here are multiple reasons why years of type 2 diabetes may lead to dementia. One T reason is related to the effects that diabetes has on the heart, as heart health is related to brain health. Heart disease and elevated blood pressure are both associated with strokes that, in turn, can lead to dementia. However, strokesdo not appear to be thecomplete answer, as somestudiesfound that diabetes led to an increased risk of dementia even when strokes were controlled for. Another factor relates to theepisodes of hypoglycemiathat commonly occur in diabetes. Although tight control of blood sugars has been proven to reduce the long-term risks of heart disease and strokes, tight control can also lead to hypoglycemia, memory loss, and dementia. Here, the reason is likely because low blood sugars are known to damage the hippocampus — the memory center of the brain. ne of the more intriguing hypotheses is that diabetes directly causes Alzheimer's O disease. Indeed, Alzheimer's disease has even been called "type 3 diabetes" because of shared molecular and cellular features among diabetes and Alzheimer's. For example,insulin plays a critical rolein theformation of amyloid plaques, and insulin is also involved in the phosphorylation of tau, which leads to neurofibrillary tangles. In other words, whereas insulin resistance in the body can lead to type 2 diabetes, insulin resistance in the brain can lead to the plaques and tangles of Alzheimer's disease. Treatment of Alzheimer’s Disease There is no cure for Alzheimer's disease. Treatment considerations included are: M ● anagement of behavioral symptoms ● Helping patients maintain brain health
n cause some of the symptoms of Alzheimer’s disease. hese drugs can improve some memory problems and reduce some behavioral T symptoms of Alzheimer’s disease.
