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    DPT 5111

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    charlie
    This document provides instructions for a case study involving the post-mortem examination of bovine brains showing normal and abnormal tissue. Case 1 involves a brain with severe cerebral congestion. Potential differential diagnoses for this congestion include: 1) active inflammation such as meningitis, 2) water deprivation or salt poisoning from excessive sodium intake or brackish water, and 3) cerebral babesia infection. Samples would need to be collected and tests run to confirm the diagnosis.

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    DPT 5111

    Uploaded by

    charlie
    18 views3 pages
    This document provides instructions for a case study involving the post-mortem examination of bovine brains showing normal and abnormal tissue. Case 1 involves a brain with severe cerebral congestion. Potential differential diagnoses for this congestion include: 1) active inflammation such as meningitis, 2) water deprivation or salt poisoning from excessive sodium intake or brackish water, and 3) cerebral babesia infection. Samples would need to be collected and tests run to confirm the diagnosis.

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    This document provides instructions for a case study involving the post-mortem examination of bovine brains showing normal and abnormal tissue. Case 1 involves a brain with severe cerebral congestion. Potential differential diagnoses for this congestion include: 1) active inflammation such as meningitis, 2) water deprivation or salt poisoning from excessive sodium intake or brackish water, and 3) cerebral babesia infection. Samples would need to be collected and tests run to confirm the diagnosis.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    18 views3 pages

    DPT 5111

    Uploaded by

    charlie
    This document provides instructions for a case study involving the post-mortem examination of bovine brains showing normal and abnormal tissue. Case 1 involves a brain with severe cerebral congestion. Potential differential diagnoses for this congestion include: 1) active inflammation such as meningitis, 2) water deprivation or salt poisoning from excessive sodium intake or brackish water, and 3) cerebral babesia infection. Samples would need to be collected and tests run to confirm the diagnosis.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    DPT 511 - Production animals

    Bovine Pathology Case studies 2021

    Instructions

    1. Provide one or more morphological diagnosis


    2. Provide an aetiological diagnosis or develop a list of differential diagnosis – to know what samples to focus on
    3. List key epidemiological features for the diagnosis or each of the DD’s
    4. List the specimens to be collected and diagnostic tests to be performed to confirm a diagnosis for each DD.
    What is normal and abnormal and the lesions

    Case 1 – Pulp Kidney

    Transection of 2 brains
    Top

    - Normal brain tissue


    - Pale grey appearance Diagnosis

    Bottom - brain smear at PM

    - Abnormal affected animal


    - Severe cerebral congestion
    - Pink to intense red ldiscolouration
    DDs for the severe cerebral congestion
    Inflammation

    - active congestion or hyperaemia


    - Could be a meningitis – with an outer membranous structure, with pia mater
    and sub arachnoid tissues – highly intensely reddened – will not enter into white
    matter
    - Low on the list, but still NB, when you open the brain and see the brain from an
    outside surface

    Water deprivation / salt poisoning

    - animals taking too much salt? – more of a situation with water deprivation –
    excessive accumulation of sodium chloride in the brain tissue but is the result of
    long-term dehydration and sudden rehydration, than taking in a lot of salt.
    - Salt is added to the feed to restrict intake – so its unlikely that the animals will
    poisoning themselves with salt by taking in a lot of salt
    - Taking in too much brackish water – water with high salinity and animals forced
    to drink the water – then you can get salt poisoning with excessive salts
    - Moving to anew camp with no water – then realized later, but is dangerous
    when you suddenly rehydrate the animals -> the salt content in the brain
    - increase and a lot of water in circulation will allow brain to absorb and
    overhydrate -> brain oedema with Neurological signs and death

    Cerebral babesia (babesia bovis, babesia bigemina)

    - cerebral babesia bovis in this case - > on a microscopic level the red blood cells
    that are parasitised, sludge into the capillaries of the cortex and causing
    congestions -> macroscopically evident
    - intensity of congestion can be variable – make a brain smear if unsure

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