Protein Synthesis

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DETAILED LESSON PLAN IN LIVING THINGS AND THEIR ENVIRONMENT 10

Grade Level Quarter/Domain Date:


Grade 10 Quarter 3 March, 2024

I. OBJECTIVES Student’s Response


A. Content The learners demonstrate an understanding of the information stored in DNA Not Applicable
Standard as being used to make proteins
B. Performance
standards
C. Learning Explain how protein is made using information from DNA
Competencies
(LC Code) (S10LTIIId-37)

At the end of the lesson, 75% were able to:


D. Specific 1. Explain the process of DNA replication, translation, transcription, and cell
Objectives: cycle.
2. Enumerate the step-by-step process of DNA replication, translation,
transcription, and cell cycle.
3. Reflect on the importance of making protein out of the concept of DNA.
II. CONTENT
A. Topic CENTRAL DOGMA Not Applicable
B. Numeracy and
Literacy
C. Integration to
other Discipline

III. LEARNING RESOURCES


References Not Applicable
1. Teacher’s Guide pages N/A
2. Learners’ Mat. Pages N/A
3. Other Learning
Resources
IV. Procedures (This includes preparatory activities such as PRAYER, CLASS RULES, and CHECKING OF ATTENDANCE.)
A. Reviewing ELICIT (5 mins)
previous lesson
or presenting A. The teacher and students will do the preliminaries (Greetings,
the new lesson Prayer, and attendance)
B. The teacher will remind the students about the classroom rules.

Classroom Rules
1. Be kind to your classmates and teacher
2. Listen to the teacher
3. Work cooperatively with your group mates
4. Raise your hand to talk
5. Work in a safe manner
To check on learners’ retention and mastery of previous lesson, the student will
play a game entitled RED LIGHT, GREEN LIGHT
True
True
True
False
True

DNA is a double helix and


“Class, can you tell me about the differences between DNA and RNA? RNA is a single helix. RNA
uses uracil while DNA
uses Thymine.

Yes, it codes instructions


“Very good! Now, do you think DNA has to do with protein synthesis?” for the synthesis of
protein.

To produce or to make.
“What do you mean by synthesis by the way?

B. Establishing a ENGAGE (5 mins)


purpose for the
lesson To start the new lesson the students will play a game called Arrange Me where
they are going to arrange the jumbled words by interpreting what the pictures
show.

Activity 1 – Arrange Me!


The students will supply the missing words below using the picture on the
right side as the hint of the word

“CELL”
1. C_L_ smallest unit of life
DEOXYRIBONUCLEIC
ACID
2. D_O_Y_IB_NU_LE_C A_I_ hereditary material in humans
C. Presenting
Examples/ 3. R_P_IC_A_TI_ _ process of duplicating or copying DNA. REPLICATION
instances of the
new lesson 4. M_TO_IS active cell division MITOSIS

5. _ES_E_GE_ R_ _ involved in protein synthesis mRNA


Guide Question:
1. Do you think these terms has to do with protein synthesis? Why? Some of these are the
ingredients in protein
synthesis while the others
are the process involved in
the production of protein.
2. From the word protein synthesis, what can you infer? Production of protein.

D. Discussing new EXPLORE (15 mins)


concepts and GALLERY WALK
practicing new
skills #1
The teacher will assign 4 leaders and each leader should have an assistant.
Learners are expected to
This activity is entitled “GALLERY WALK” The remaining students will roam
listen actively and
around to their respective stations and will answer the provided guide attentively to the
questions. Each leader will be given a topic, and you are going to make a instructions and guidelines
model and they are going to make a model and discuss the concept of it. and raise any questions or
clarifications, when
necessary.
1st Reporter: Cell Cycle
E. Discussing new
concepts and 2nd Reporter: DNA Replication
practicing new 3rd Reporter: DNA Transcription
skills #2 4th Reporter: DNA Translation
Group 1
Guide Questions:
1) During which phase of the cell cycle is DNA  S phase
synthesized?  Interphase and
2) List down the different stages of the Cell Cycle Mitosis
3) Summarize what happens during the Cell Cycle.  During the
interphase, the
cell grows, or the
cell growth occurs
here. During the
M phase the cell
divides.

Group 2
Guide Questions: The process of copying
1. Describe the process of DNA Replication DNA
2. Why does DNA Replicate? To carry a correct set of
genetic information
3. What type of enzyme breaks the bonds between nitrogenous
Helicase
bases so that the DNA will split?

Group 3
Guide Questions:
1. What is transcription? It is the process of
2. How does mRNA molecule carry information from DNA? converting DNA to RNA
3. During transcription, what does mRNA do? Only one is transcribed
and it carries information
from DNA
It carries the set of
information from DNA

Group 4
Guide Questions:
The process of translating
1. Describe the process of translation mRNA to protein
2. What is the term for a three-nucleotide sequence that codes for an Codon
amino acid? Initiation, Elongation, and
3. What are the three stages involved in translation?
Termination

Rubrics:
Content – 20 points
Presentation – 15 points
Teamwork – 10 points
Timeliness – 5 points

F. Developing EXPLAIN (10 mins)


Mastery (Leads
Formative The teacher will emphasize the following:
Assessment 3)
DNA is made up of sugars,
- DNA is made up of?
phosphate groups, and
nitrogenous bases and its
shape is a double helix.
The complementary
structure the two strands
of DNA allow each strand
to serve as a template
during replication

The specificity of base


- How important is the base pairing of the DNA? pairing in DNA, adenine
with thymine, and cytosine
with guanine, allows DNA
to replicate itself with
accuracy.
- What is replication?

The sequence of
nucleotides in DNA directs
the order of nucleotides in
messenger RNA in
- What is transcription?
process called
transcription.

There are three major


types of RNA that help
- What are the three major types of RNA? build proteins: mRNA,
rRNA, and tRNA

The process of converting


the information in
- What is translation? messenger RNA into a
sequence of amino acids
that make protein is known
as translation

The role of transfer RNA


- What is the role of tRNA? (tRNA) is to bring the
amino acids in the
cytoplasm to the
ribosomes to make
proteins.

S phase, Interphase, and


- The steps involved in cell cycle Mitosis
-

In this part the teacher will


emphasize the guide
question in their last
activity and the students
will listen and can ask any
question or clarification.
G. Finding practical ELABORATE (10 mins)
applications of Transcription, Translation,
concepts and Initiation, Elongation, and
skills in daily Termination
living Okay before we can make protein there are many steps that we need to
discuss. What are those?

H. Making
generalizations S phase, Interphase, and
and abstractions What are the steps in the cell cycle? Mitosis
about the lesson

process of duplicating or
Based on the activity. What is replication? copying DNA

The sequence of
nucleotides in DNA directs
How about transcription? the order of nucleotides in
messenger RNA in a
process called
transcription.
How about translation?
The process of converting
the information in
messenger RNA into a
sequence of amino acids
that make protein is known
as translation

I. Evaluating EVALUATE (5 mins)


Learning SHORT QUIZ

Get ½ crosswise and answer the following. “Student's output may


1. Describe the given word and explain the process of each word. vary”
 Cell Cycle
 DNA Replication
 DNA Transcription
 DNA Translation
2. What is the importance of making protein out of DNA and RNA?

J. Additional EXTEND (5 mins)


activities for Flyer
application or
remediation Make a flyer with the assigned topic below: “Student's output may
Group 1: Cell cycle vary”
Group 2: DNA Replication
Group 3: DNA Transcription
Group 4: DNA Translation

V. REMARKS
VI. REFLECTION
A. No. of learners
who earned 75%
in the evaluation
B. No. of learners
who require
additional
activities for
remediation
C. Did the remedial
lessons work?
No. of learners
who have caught
up with the lesson
D. No. of learners
who continue to
require
remediation
E. Which of my
teaching
strategies worked
well? Why did this
work?
F. What difficulties
did I encounter
which my
principal or
supervisor can
help me solve?
G. What innovation
or localized
materials did I
use/discover
which I wish to
share with other
teachers?

Prepared by: Submitted to:

NOLI B. CAJES JESNINIETA A. DOLORMENTE


Pre-service Teacher Master Teacher III

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