Oulun Yliopisto e Thesis
Oulun Yliopisto e Thesis
Oulun Yliopisto e Thesis
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Sharpe and Zackon (1987) found that saccadic peak velocity is significantly reduced in the elderly
compared to the young, for saccades predictable by target amplitude and direction, but that there is
no difference between these groups in saccades that are nonpredictable by target amplitude and
direction. Videooculography - an alternative method for measurementof three-dimensional eye
movements. These findings of phase differences in different age groups are in line with the findings
of Sharpe and Sylvester (1978) (constant velocity ramp movement), Morrow and Sharpe (1993)
(step-ramp stimuli), and Paige (1994) (predictive oscillating movement). Leigh RJ, Zee DS. Smooth
pursuit and ocular stabilization. The remaining masses include primary cholesteatoma (2%), facial
nerve neuroma (1%), neuromas of other cranial nerves (0.2%) and other rare tumors (e.g.,
hemangioma, astrocytoma, medulloblastoma, glomus tumor) (Thomsen 1976; Brackmann and
Bartels 1980; Berlinger et al. 1980). Vestibular schwannoma The largest and most common tumor in
the CPA is vestibular schwannoma (Eldridge and Parry 1992). Int J BiomedComput 1988(b); 22:
239-250. Juhola M. On syntactic pattern recognition methods in computer analysis of eye
movements.Trends Biol Cybern 1990; 1: 33-44. Juhola M. Computer procedures for verification of
nystagmus eye movements in patternrecognition of nystagmus signals. In PRPEM with a 0.25 and
0.425 Hz frequency and a 0.45 and 0.7 Hz frequency combination, operated HAB patients had
distinctly lower GAs than control subjects. Parameters Saccades SRT, saccadic accuracy and
saccadic peak velocity have often been assessed in saccade tests. In PRPEM with both frequency
combinations used, patients with infarction of cerebello-brain stem had distinctly lower GAs than
control subjects. In patients with tumors larger than 15-20 mm, tests for eye movement, ABRs and
stapedius reflex were pathologic. Collewijn H. Eye and head movements in freely moving rabbits. In
addition, some of the vestibular schwannoma patients manifested a cochlear type of hearing loss
rather than a retrocochlear type (Flood and Brightwell 1984). The photocells detect the amount of
infrared light reflected from the surface of the eye (Smith and Warter 1960; Stark et al. 1962; Yee et
al. 1985). According to Boghen et al. (1974), the saccadic peak velocities at horizontal saccades in
certain saccade amplitudes are higher in normal subjects when recorded by the IROG method than
when recorded by the EOG method. The amount of phase lead and phase lag in PEMs varies
according to the extent of predictability of the stimulus (Stark et al 1962; Young and Stark 1963;
Michael and Melvill Jones 1966). Irrespective of whether the finding was unilateral or bilateral, it
was classified as one. Receptive fields and functional architecture in the cat’s visual cortex. Saccades
In constant saccades of control subjects, the SAs, SRTs and SPVs were the best, and the variance
was the smallest in control subjects. These studies show that one must be careful when comparing
the results of different studies with different kinds of saccade stimuli. Both signals were divided into
consecutive segments. According to Lalwani (1992), clinical manifestations of CPA meningiomas are
similar to those of vestibular schwannoma (hearing loss and tinnitus) and are to some extent, more
common in vestibular schwannoma, but trigeminal dysfunction occurs more often in CPA
meningiomas. In cases of severe Meniere’s disease, it is very difficult to find any effective treatment
for acute attacks. This work indicates that in patients with peripheral or central lesions along the
pathways for voluntary eye movements, there were timing errors (lengthened SRT, lengthened phase
lag or saccadization of PEM) in voluntary eye movements. In studying the gender differences in
voluntary eye movements, the statistical analysis was done with Student’s t-test in two independent
samples (Norusis 1993). However, as in patients with cerebellar lesions, the velocity and timing of
saccades were significantly deteriorated in patients with cerebello-brain stem lesions. Allum et al.
(1991) observed that the performance in PEM could differentiate control subjects and patients with
peripheral vestibular disorder, from patients with central vestibular disorders. When artificial
intelligence that “learns from previous experience” was used with the whole voluntary eye
movement performance data in the localization task, the accuracy was further improved (correct
localization in 91.4 - 97.1% of all cases). Page 121. According to Buttner et al. (1994), the fastigial
nuclei lesions and oculomotor vermis lesions cause hypermetric saccades, but PEM is preserved in
those lesions. Juhola et al. (1985b), Juhola (1986) and Juhola and Pyykko (1987), observed that the
lowest sampling frequency should be 400Hz to allow for saccade identification. But the difference
between these studies is that in the present study, the amplitude of pursuit was also significantly
reduced. Oxford: Pergamon Press1975; 47-61. Miller LK. Eye movement latency as a function of
age, stimulus uncertainty and position in thevisual field.
In the study of Bergenius (1985), oculomotor disturbances were noted in nearly half of the
retrocochlear group. This means that every time you visit this website you will need to enable or
disable cookies again. This study focuses on the accuracy of voluntary eye movements to reveal
certain diseases affecting the peripheral or central vestibular system and the central oculomotor
system. This might be affected by the hemispheric dominance. The mean of the PTA was 58 dB,
ranging from 8 to 120 dB. According to Selesnick and Jackler (1992), CPA tumors compressing the
brain stem cause ipsilateral lesions first, but when the tumor is very large, lesions in the contralateral
side can be found, too (Selesnick and Jackler 1992). Saccades are fast eye movements that are used
when gazing at different objects, scanning the horizon, or when bringing targets of interest onto the
fovea. Velocity gain values of PEMs are influenced by target motion characteristics: target velocity,
target acceleration, motion amplitude, and target frequency (Versino and Cosi 1990). The device for
recording MOG consisted of 2 vertical and 2 horizontal induction coils 0.73 and 1.10 m in diameter
respectively, the verticals were at a distance of 0.38m from each other and the horizontals were at a
distance of 0.57m from each other. The system was custom-made. Meniere’s disease is also
characterized by attacks of rotatory vertigo and short lasting drop attacks, but in those cases with
intractable Meniere’s disease, patients often complain of unsteadiness and gait disorders even during
attack-free periods (Pyykko et al. 1994b). They often complain about postural instability and
dizziness when moving by themselves or when the visual surrounding is moving. Smooth pursuit eye
movements in response to unpredictabletarget waveforms. Vision Res 1980; 20: 923-931. Studies of
the velocity of saccadic eye movements with specialreference to aging changes. It occurs when the
pulse is too small or too large for the demanded amplitude change. The frequency combination of
0.25 and 0.425 Hz was chosen for further analysis in order to reduce the testing time in examining
patients with Meniere’s disease. Computer analysis of sinusoidal eye movements using
patternrecognition. Afferent and efferent connections of the oculomotor region of thefastigial
nucleus in the macaque monkey. The use of a single voluntary eye movement test is not effective in
evaluating the site of the lesion, or the diagnosis. Yliopiston tavoitteena on turvata yha useammalle
nuorelle vayla korkeakoulutukseen ja aikanaan tyomarkkinoille. With standard photoelectric
recording techniques, the mean of normal peak velocity for 20. With a frequency combination of
0.45 and 0.7Hz, correct classification was achieved in 74% of all cases of discriminant analysis
(Figure 13). The GA and the mean phase reduced with rising frequency combinations. The timing of
a saccade is controlled by a separate mechanism from that which controls amplitude (Findlay 1981).
The performance ability in different voluntary eye movements (constant and pseudo-random
saccades, PRPEM with different frequency combinations) could accurately classify control subjects
and patients with lesions at different sites of the neural system into correct groups. Unilateral frontal
eye fieldlesions degrade saccadic performance in the rhesus monkey. However, according to
Amarenco et al. (1990), Pierrot- Deseilligny et al. (1990), and Magnusson and Norrving (1993), in
cerebellar infarctions vertigo is the first and the most prominent, if not the sole, symptom.
Repeatability of pseudo-random pursuit eye movement tests Assessing of the reliability of eye
movement tests has been done in a few previous studies, though most of them were not systematic.
Flocculus is unilaterally injured but brain stem, fastigial nucleus and oculomotor vermis are bilaterally
injured. Page 79. Results: SA and pursuit gain (GA) and phase (mean phase) were deteriorated with
advancing age in elderly subjects. The input and output of the final common integrator are summed
to generate the pulse-step, and consequently, the motor neuron activity required to produce a saccade
(Carpenter 1988). Intracranial and intratemporalmeningiomas with primary otologic symptoms.
Otolaryngol Head Neck Surg 1988; 99: 444-454.
Saccades are fast eye movements that are used when gazing at different objects, scanning the
horizon, or when bringing targets of interest onto the fovea. PPRF also has projections to the
contralateral PPRF, the pretectal area, the prepositus hypoglossi nucleus and medial vestibular
nucleus (Buttner-Ennever and Henn 1976). In operated HAB patients, GA differed significantly (p
measures ANOVA) and mean phase tended to differ (p frequency combinations. She had normal
PRPEMs. Figure 9a-b shows her recordings of pseudo-random saccade tests and a part of one
PRPEM recording. Page 77. PEM parietal lobe, FEF, visual cortex, temporal lobe oculomotor vermis
sacc. For patients with cerebellar lesions, 6% were incorrectly classified to brain stem lesions.
Otolaryngol Head Neck Surg 1982; 90: 256-262. Blakley BW. Electronystagmography: The
standardization process. Both caused saccadization of PEMs. Psychological factors, such as
motivation and attention (Becker and Fuchs 1969; Shagass et al. 1976; Schmidt et al. 1979;
Robinson 1981; Siever et al. 1989; Versino and Cosi 1990), and cognitive expectation (Kowler and
Steinman 1981; Kowler 1989), can affect the PEM and saccadic performance. In addition, some of
the vestibular schwannoma patients manifested a cochlear type of hearing loss rather than a
retrocochlear type (Flood and Brightwell 1984). In peripheral patients, 48% were correctly
classified, 22% of the cases were incorrectly classified as control subjects. Primate frontal eye fields.
II. Physiologicaland anatomical correlates of electrically evoked eye movements. Loss of the neural
integrator of the oculomotor system from brainstem lesions in monkey. I also want to thank Professor
Martti Juhola, my supervisor, for his profound knowledge of computer science, his skillful solutions
of problems concerning eye movement assessment and recording and for his guidance and support.
According to Wheeless et al. (1966), the eye has a 32% chance of altering its response if the target
change occurs 85 ms before a saccade. Yliopiston tavoitteena on turvata yha useammalle nuorelle
vayla korkeakoulutukseen ja aikanaan tyomarkkinoille. Pursuit eye movements and their neural
control in the monkey.Pflugers Arch 1978; 337: 15-23. Electrooculographic syndrome in monkeys
after pontinereticular formation lesions. Philadelphia: FA DavisCompany 1981. 405 pp. van
Gisbergen JAM, van Opstal AJ, Roebroek JGH. However, PEM measures could not significantly
differentiate patients with central vestibular disorder from patients with vestibular schwannoma.
Generation of smooth-pursuit eye movements: neuronal mechanismsand pathways. Note the
connection to the saccadic system via the visual nuclei of pons and oculomotor vermis. Already
Weber and Daroff (1972) had suggested that a feedback from proprioceptors in extraocular muscles
might play a role in corrective saccadic eye movements rather than the visual feedback. However, in
later studies it has been discovered that visual information can be continuously acquired and used to
modify the initial saccade until just about 70 ms before the movement begins (Wheeless et al. 1966;
Becker and Jurgens 1979; Ottes et al. 1984). This has been found in experiments where the so-called
double-step stimulus has been used. In the curve estimation procedure, the linear, quadratic and cubic
functions were applied. When the duration of Meniere’s disease is long and vertigo attacks are
frequent, unsteadiness persists between the attacks, which is a sign of irreversible damage to the
vestibular sense organ (Schucknecht 1957). An ophthalmologist made neuro-ophthalmologic
examinations of all patients with HAB. Slowing of eye velocity of PEMs in large CPA tumors found
by Baloh et al. (1976) is reflected via the saccadization of PEMs to the reduced GAs. The tree may
consist of a test that has a set of different possible outcomes. In their study, the number of subjects
tested was large, but the target displacements in saccades were different between this and previous
studies mentioned above. Eye movements were tested before (49 patients) and after (13 patients) the
intratympanic gentamicin treatment.
In the study of Takagi et al. (1998), the lesions of dorsal vermis in monkeys seem to affect saccadic
eye movements profoundly. Effects of lesions of the oculomotor vermis on eye movementsin
primates: Saccades. The noise can increase the noise floor, thus reducing the sensitivity of the
recording system or distort recorded signals, thus changing the results computed from them. One-
way analysis of variance (ANOVA; Scheffe’s test) (Norusis 1993) was used to study the possible
differences in voluntary eye movements between different age groups. PPRF is regarded to be a
supranuclear structure responsible for conjugate horizontal eye movements (Cohen and Komatsuzaki
1972; Keller 1974; Henn and Cohen 1976; Hepp and Henn 1983). Deficits in smooth-pursuit eye
movements following lidocaineinjection in monkey nucleus reticularis tegmenti pontis (NRTP). After
a review of the literature, there appears to be no studies of saccade tests and pursuit tests in patients
with CPA medulloblastoma. Methodological and physiological aspects and the vulnerability of the
oculomotor system are also studied. Cookie information is stored in your browser and performs
functions such as recognising you when you return to our website and helping our team to
understand which sections of the website you find most interesting and useful. Hepp K, Henn V.
Spatio-temporal recording of rapid eye movement signals in the monkeyparamedian pontine reticular
formation (PPRF). This could explain why the oculomotor pathology was not restricted only to the
ipsilateral parameters. This profile is therefore, preserved in many diseases causing vertigo.
Classification of control subjects were correct 78% of the time, Page 87. Meniere’s disease was
bilateral in 13 out of 62 patients. The trajectories of voluntary eye movements travel commonly
through the same neural circuitries as those of the central vestibular system (Gilman et al. 1981; Ito
1984). Disorders of the vestibular system can also affect the oculomotor system. Overall correct
classification in pseudo-random saccades was achieved in 56% of all cases. Clinical,
psychophysiological and neurological characteristics of volunteerswith impaired smooth pursuit eye
movements. In control subjects, 60% were correctly classified, 29% were incorrectly classified into
the peripheral group, and 11% incorrectly into the central group. Innov Technol Biol Med 1991(a);
12: 364-374. Juhola M. Median filtering is appropriate to signals of saccadic eye movements.
Findlay’s analysis supports the idea of a distinction in accuracy between the anticipatory and the
visually guided saccades. Saccadic peak velocity and saccadic amplitude have a non-linear
relationship (Zuber et al. 1965; Fuchs 1967a; Schmidt et al. 1979; Leigh and Zee 1983a); saccadic
Page 35. Neurology 1992;42: 2274-2279. Odkvist LM. Otoneurological diagnostics in posterior fossa
lesions. Vision Res 1983; 23: 33-37. Alley K. Anatomical basis for interaction between cerebellar
flocculus and brainstem. To some extent reduced attention span belongs to normal aging, and it can
affect PEM performance in the elderly (Versino et al. 1993a). This was also seen in the present study
with respect to PRPEMs in elderly subjects. Effects of occipital lobectomy upon eyemovements in
primate. Limits of ABR and contribution of transtympanicelectrocochleography in the assessment of
cerebellopontine angle tumors. A glissade is the final process where the eye finally slides to the
predetermined position (Robinson 1964; Fuchs and Luschei 1970). PEM is driven by visual motion
information, and impaired pursuit initiation in elderly subjects compared to young and middle-aged
subjects could be caused by senescent degradation of afferent visual motion inputs (Morrow and
Sharpe 1993). Adobe Express Go from Adobe Express creation to Issuu publication. Nucleus
prepositus hypoglossi and medial vestibular nucleus have reciprocal connections to the
vestibulocerebellum (Alley 1977; Lisberger and Fuchs 1978).
The difference between these two constitutes a motor error signal (Carpenter 1988). For example,
there are projections via the vestibular complex and the inferior olivary complex to the cerebellum
(Noda et al. 1990; Noda 1991). The cerebellar output, through fastigial oculomotor region via the
contralateral uncinate fasciculus (Noda and Ikeda 1989), independently influences the horizontal and
vertical saccades (Fujikado and Noda 1987). Both the saccades and PEMs have errors of timing in
operated CPA tumor patients. The GA was lower in the young and elderly than in the middle- aged
subjects with different frequency combinations. The correlation of voluntary eye movement deficits
to subjective symptoms and clinical data of patients was also analyzed. Irrespective of whether the
finding was unilateral or bilateral, it was classified as one. Kaupunkisuunnittelu pandemioiden
ennaltaehkaisyn valineena (RECIPE). Corrective movements following refixation saccades: Type
and controlsystem analysis. However, according to Amarenco et al. (1990), Pierrot- Deseilligny et al.
(1990), and Magnusson and Norrving (1993), in cerebellar infarctions vertigo is the first and the
most prominent, if not the sole, symptom. Disturbances of conjugate horizontal eye movements in
themonkey. House JL, Burt MR. Primary CNS tumors presenting as cerebellopontine angle tumors.
This visual “overruling” in moving visual surrounding causes “postural vection” and indicates a
distrust of the central postural system on vestibular detectors of the inner ear (Pyykko et al. 1994a).
If there is a mismatch between the visual information and the information coming from the affected
vestibular system as in Meniere’s disease, it could result in the timing error found in this work. This
may be due to the frequent correcting saccades demonstrated by patients with vestibular
schwannoma in the eye tracking test (Allum et al. 1991). Pierrot-Deseilligny et al. (1990) observed
an infarction in the region of the left PICA (mainly its medial branch) in a patient that was 80 years
old. Deficits in visual motion processingfollowing ibotenic acid lesions of the middle temporal visual
area of the macaque monkey.J Neurosci 1985; 5: 825-840. Noda H. Cerebellar control of saccadic
eye movements: Its neural mechanisms and pathways.Jpn J Physiol 1991; 41: 351-368. Yliopiston
tavoitteena on turvata yha useammalle nuorelle vayla korkeakoulutukseen ja aikanaan
tyomarkkinoille. This is in line with the findings of Michael and Melvill Jones (1966) and St-Cyr and
Fender (1969). Page 107. Role of the striate cortex in generation ofsmooth pursuit eye movements. J
Optic Soc Am 1967; 57: 1030-1033. Schalen L. 1981. Saccades, fast phases of nystagmus and
tracking eye movements in man. Metrics of horizontal saccadic eye movements in normal humans.
From this group, 31 patients had vestibular schwannomas, four had meningiomas, one had a glomus
jugulare tumor and one had a medulloblastoma. A FEF lesion transiently impairs predictive and
visually guided PEM, and PEM appears to be more vulnerable to lesions than saccades (Keating
1991). The majority of downbeat nystagmus patients (72 out of 91) were tested with eye movement
tests, and almost all (99%) had abnormal horizontal eye movements of cerebellar pattern (including
impaired PEMs, impaired OKN, inability to suppress VOR) (Yee 1989). In saccades, the purpose of
the neural activity of the flocculus is to adjust the pulse size to eliminate a glissade (Optican and
Robinson 1980). The probability of the stimulus to move to the left or right was 0.5 for each, so the
required saccadic amplitude was predictable. No specific eye movement disturbance may be linked
to a specific anatomic site in cerebellum or brain stem in clinical studies of patients, or chronic
patients. Yli 20 paikan lisayksen saavat myos tekniikan alat (25), humanistiset ja yhteiskunnalliset
alat (24) ja luonnontieteet (23). According to Selesnick and Jackler (1992) and Nedzelski (1983), in
large vestibular schwannoma tumors there are ENG disorders, including saccadic PEMs and bilateral
saccade overshoot. In patients with infarction of cerebello-brain stem, deficits in voluntary eye
movements correlated with certain MRI findings. In the future, the correlation of subjective
symptoms of a patient with vertigo and their whole voluntary eye movement performance should be
evaluated in order to aid diagnosing. Page 122. According to Nedzelski (1983), the oculomotor
system is seldom affected by small or medium sized tumors ( tumors, the PEM defects are most
commonly bilateral; in saccadic eye movements, the saccadic accuracy is impaired (saccades are
hypermetric), but saccadic peak velocity is normal (Nedzelski 1983).
The DLPN and nucleus reticularis tegmenti pontis also receive inputs from the superior colliculus
(Harting Page 18. Both the caudal and temporal PPRF neuronal populations contain long-lead and
medium-lead burst neurons (Hepp and Henn 1983). It is also possible that lateral hemispheres of
cerebellum and anterior superior vermis can participate in PEMs as well (Zee et al. 1981).
Cerebellum exerts control on PEMs through several pathways: the vestibular nuclei (Langer et. Acta
Otolaryngol(Stockh) Suppl. 1993; 503: 64-66. Page 133. The clinical picture of medulloblastoma is
almost always that of a posterior fossa tumor (Rubinstein 1972). But predictive settings lead to
anticipatory rather than “tracking” saccadic performance (Saslow 1967). The analysis starts with a
sample of objects that belong to one of the possible classes. The flocculus and nodulus are frequently
compressed by large vestibular schwannoma, causing the flocculonodular syndrome of dysfunction
(Selesnick and Jackler 1992). GIFs Highlight your latest work via email or social media with custom
GIFs. Stapedius reflex test, brainstem audiometry and opto-vestibular tests in diagnosis of acoustic
neurinomas. The working capacity was assessed according to Total Handicap Score of AAO-HNSF
in 1985 (AAO-HNS 1985; Pearson and Brackmann 1985), in which the working capacity is
expressed on a four-point scale. According to Warabi et al. (1984), the most prominent change in
saccades in healthy elderly subjects is the prolongation of time to catch a target. In the constant and
pseudo-random saccades, mean age of control subjects was 48 years (18-88 years); 30 were females
and 15 were males. Role of the striate cortex in generation ofsmooth pursuit eye movements. This is
in line with the findings of Michael and Melvill Jones (1966) and St-Cyr and Fender (1969). Page
107. Lateral extent of internal auditory canalinvolvement by acoustic neuromas: a surgical-radiologic
correlation. It presents with isolated vertigo, vertigo associated with cochlear symptoms, or vertigo
associated with dysfunction of the dorsal lateral pons and cerebellum (Oas and Baloh 1992).
Efferent projections from the superior colliculus reach the eye movement centers located in PPRF
(Harting 1977; Lynch et al. 1977). The functional properties of the visual neurons in parietal lobe
match completely with those of the premotor neural activity recorded in PPRF (Lynch et al. 1977),
indicating a functional connection. Median filters: Some modifications and their properties. The
study protocol was reviewed and approved by a local ethical committee at the Helsinki University
Central Hospital (HUCH). 4. A. 2. Patients a) Meniere’s disease Sixty-two patients with moderately
severe to severe Meniere’s disease were examined. The present study also confirms the findings of
Larsby et al. (1988), showing that the accuracy of eye movements in children and teenagers is not
matured when compared to the middle-aged. Facial nerve motor dysfunction tends to occur
gradually, in later stages of vestibular schwannoma (Selesnick and Jackler 1992). The PEM test was
saccadic in one patient and normal in the others. Sharpe and Zackon (1987) have studied the
differences between non-predictable and predictable saccades, and their findings were confirmed by
the findings of the present work concerning its healthy subjects. According to Leigh and Zee
(1983b), and Versino and Cosi (1990), the PEM system conducts three tasks: 1) continuous
visualization of target moving in a stable visual environment, 2) suppression of vestibulo-ocular
reflex during eye tracking, and 3) image stabilization during fixation. Versino M, Beltrami G,
Zambarbieri D, Castelnovo G, Bergamaschi R, Romani A, Cosi V. According to Warabi et al. (1984),
SRT is dependent on the amplitude of the saccade. Receptive fields and functional architecture in
the cat’s visual cortex. Basic Mechanisms of Ocular Motility and TheirClinical Implications. In the
present work, a tendency for rightward saccades to be slower than leftward saccades (in paired
samples t-test) was observed.
The length of the segment was chosen to be 0.040s (Juhola 1991c). Using linear regression, a slope
for each segment was computed that was equal to the mean velocity with regard to that segment
(Juhola 1991c). The mean phase was at its shortest in the middle-aged group (one-way ANOVA). In
PRPEM, this error in timing was reflected in reduced GA. Then, an oculomotor deficit may be
produced which would not have been present with either Page 114. Meniere’s disease is also
characterized by attacks of rotatory vertigo and short lasting drop attacks, but in those cases with
intractable Meniere’s disease, patients often complain of unsteadiness and gait disorders even during
attack-free periods (Pyykko et al. 1994b). They often complain about postural instability and
dizziness when moving by themselves or when the visual surrounding is moving. The mean age of
the subjects was 50 years (range 15.5 to 87 years). d. Side difference The laterality of saccades was
studied on the 45 subjects of the normative data group. e. Repeatability The PRPEM tests were done
in two different days to 17 normal subjects who were tested for analyzing the repeatability of
PRPEM. In control subjects, 76% of the cases were correctly classified, and 22% placed incorrectly
as peripheral patients. According to this work, a pure vestibular lesion (with advanced severity) can
cause disorders of voluntary eye movements. Nowadays, at the University of Oulu, you can study in
more than 20-degree programs representing nine fields of study. In one-way ANOVA (Scheffe’s test),
several statistically significant differences were found (Table 12a-b). Table 12a. Operated CPA
patients and operated HAB patients. Syntactic Pattern Recognition Method of Eye Movement: The
recognition and analysis programs of eye movements were implemented in Pascal programming
language (Juhola et al. 1989). The computer used a syntactic method for the recognition and analysis
of eye movements. They found considerable intra- and intersubject variability, and they concluded
that it is necessary to record a sufficient number of subjects and eye movements (of certain
magnitude) to accurately define these responses. The disadvantage of the MOG method (i.e., the
inconvenience it causes to the subject) restricts its use in routine tests. The analysis of vertical
saccades by EOG was, therefore, limited by the waveform artifacts that occurred with both upward
and downward saccades (Chioran and Yee 1991). According to Selesnick and Jackler (1992), CPA
tumors compressing the brain stem cause ipsilateral lesions first, but when the tumor is very large,
lesions in the contralateral side can be found, too (Selesnick and Jackler 1992). In: Symon L,
Calliauw L, Cohadon F, Lobo Antunes J, Loew F,Nornes H, Pasztor E, Pickard JD, Strong AJ,
Yasargil MG, eds. There will be a subsidiary decision tree for each outcome. In this present work, no
significant differences in the laterality of SRTs were found. Robinson DA. A method of measuring
eye movement using a scleral search coil in a magneticfield. In control subjects, the effect of age and
gender on voluntary eye movements, as well as the laterality of saccades and repeatability of
PRPEM tests were tested. Esimerkiksi monialaisella Business Analytics -tutkinto-ohjelmalla
vastataan syntyneeseen osaajatarpeeseen tietojenkasittelytieteissa, tietotekniikassa ja kauppatieteissa.
The nodes represent tests based on features of example cases, and leaves represent classes (i.e.
decisions). In classification, the algorithm starts at the root of the tree. Meniere’s disease was bilateral
in 13 out of 62 patients. Larsby et al. (1988) did not find the phase shift to be affected by age. The
PEM test was saccadic in one patient and normal in the others. Acta Otolaryngol Suppl (Stockh)
1991; 481: 466-467. Duhamel JR, Goldberg ME, Fitzgibbon EJ, Sirigu A, Grafman J. Committee on
hearing and equilibrium of AAO-HNSF: Committee on hearing and equilibriumguidelines for the
evaluation of results of treatment of conductive hearing loss. The timing of saccades in operated
CPA tumor patients is deteriorated. The Civil Engineering research unit can be found on the third
floor, rooms TF301-309 and PR301-303, to which the most direct route is through main doors 2T
and stairway T1 up.