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Cyclobutanes

- Cyclobutanes exist in a puckered conformation to minimize eclipsing interactions between C-H bonds. Their inherent ring strain makes formation of cyclobutanes difficult but also makes them useful in organic synthesis. - Cyclobutanes are the basic structural units in bacteria, fungi, plants and marine invertebrates. They are involved in many biological activities and often exhibit protective properties. - Some methods to form cyclobutanes include photochemical [2+2] cycloaddition of olefin substrates, transition metal-catalyzed [2+2] cycloadditions, and thermal ring closure via 1,4-radical processes. Most naturally occurring cyc

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0% found this document useful (0 votes)
45 views9 pages

Cyclobutanes

- Cyclobutanes exist in a puckered conformation to minimize eclipsing interactions between C-H bonds. Their inherent ring strain makes formation of cyclobutanes difficult but also makes them useful in organic synthesis. - Cyclobutanes are the basic structural units in bacteria, fungi, plants and marine invertebrates. They are involved in many biological activities and often exhibit protective properties. - Some methods to form cyclobutanes include photochemical [2+2] cycloaddition of olefin substrates, transition metal-catalyzed [2+2] cycloadditions, and thermal ring closure via 1,4-radical processes. Most naturally occurring cyc

Uploaded by

Eena Barman
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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