This document provides information about the medication Ondansetron (Zofran) including its classification, dose, route, time/frequency of administration, peak effect, onset, duration, normal dosage range, mechanism of action, indications, nursing implications, interactions, lab alterations, patient teaching points, pre-administration assessment, and post-administration evaluation. The key details are that Ondansetron is an antiemetic administered intravenously to treat nausea by blocking serotonin receptors, with common side effects including headache, dizziness, and constipation. Nurses should assess for nausea and vomiting before and after administration and monitor for potential extrapyramidal effects.
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Zofran
This document provides information about the medication Ondansetron (Zofran) including its classification, dose, route, time/frequency of administration, peak effect, onset, duration, normal dosage range, mechanism of action, indications, nursing implications, interactions, lab alterations, patient teaching points, pre-administration assessment, and post-administration evaluation. The key details are that Ondansetron is an antiemetic administered intravenously to treat nausea by blocking serotonin receptors, with common side effects including headache, dizziness, and constipation. Nurses should assess for nausea and vomiting before and after administration and monitor for potential extrapyramidal effects.
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NURS 1566 Clinical Form 3: Clinical Medications Worksheets
(You will need to make additional copies of these forms)
Generic Trade Name Classification Dose Route Time/frequency
Name Zofran Antiemetics 4 mg=2mL IVP X1 PRN Ondansetron Peak Onset Duration Normal dosage range 15-30 min Rapid 4-8 hr 0.15 mg/kg or 32 mg single dose Why is your patient getting this medication For IV meds, compatibility with IV drips and/or solutions For the treatment of nausea Administer undiluted. RATE: administer over at least 30 sec and preferably over 2-5 min Mechanism of action and indications Nursing Implications (what to focus on) (Why med ordered) Contraindications/warnings/interactions Blocks the effects of serotonin at 5-ht receptor sites Hypersensitivity. Use cautiously in liver impairment; located in vagal nerve terminals and the abdominal surgery. chemoreceptor trigger zone in the CNS. Decreases Common side effects incidence and severity of nausea and vomiting CNS: headache, dizziness, drowsiness, fatigue, weakness. GI: constipation, diarrhea, abdominal pain, dry mouth, increased liver enzymes. NEURO: extrapyramidal reactions. Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine medicines (ask patient specifically) May cause transient increase in serum bilirubin, AST, and May be affected by drugs altering the activity of liver ALT levels. enzymes. Be sure to teach the patient the following about this medication Take as directed. Advise patient to notify health care professional immediately if involuntary movement of eyes, face, or limbs occur Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give this Check after giving Assess for nausea, vomiting, abdominal med? Improvement of nausea distention, and bowel sounds prior to and Patient reports that nausea has and/or vomiting. following administration. Assess patient for resolved and they are no longer extrapyramidal effects periodically vomiting. Patient is showing signs of extrapyramidal effects.
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