Endocrinology – Hormones MCQS

(Hormone acts soon if the cell has receptors for the hormone,
you will become soon successful and beautiful like moon if you are
the acceptor of whom who performed the miracle of moon)
BY

Endocrinology MCQs 1 Dr. Sajid Ali Talpur

1. It acts as a first messenger:
a) c-AMP b) c-GMP
c) calmodulin d) calcium
e) calcitonin

2. The enzyme required for the synthesis of c-AMP is:

a) tyrosine kinase b) phospholipase C
c) adenylate cyclase d) G-Protein
e) ATPase

3. An 11 years old patient comes to doctor with obesity and dwarfism. He

needs the administration of:
a) insulin b) growth hormone
c) glucagon d) testosterone
e) catecholamines

4. Find the mis-match.

a) pancreas : somatostatin
b) thyroid gland : calcitonin
c) Anterior pituitary : thyrotropin releasing hormone
d) adrenal medulla : catecholamines
e) adrenal cortex : mineralocorticoids

5. Testosterone formation in the fetus is stimulated by:

a) FSH b) LH
c) both a & b d) HCG hormone
e) anti mullerian hormone

1 E 2 C 3 B
4 C 5 D

Endocrinology MCQs 2 Dr. Sajid Ali Talpur

6. It has receptors in the cytoplasm:
a) insulin b) glucagon
c) cortisol d) growth hormone
e) oxytocin

7. The commonest cause of diabetes mellitus is:

a) carbohydrate diet b) congenital absence of insulin
c) obesity d) pancreatic atrophy
e) lack of exercise
8. Oxytocin is secreted by:
a) supra optic nuclei b) para optic nuclei
c) para ventricular nuclei d) posterior pituitary
e) uterus

9. The most appropriate option that represents an exocrine gland:

a) duct b) blood
c) hormone d) secretory vesicle

10. It may be called as master gland:

a) hypothalamus b) pituitary gland
c) thyroid gland d) pancreas
e) adrenal gland

11. All are the dissimilarities of hormones with enzymes except:

a) they are poured into blood
b) they are not used up during the reaction
c) they are produced by one organ and act on the other
d) they all are not protein in nature.

6 C
7 C 8 C 9 A
10 A 11 B 12

Endocrinology MCQs 3 Dr. Sajid Ali Talpur

12. It has receptors in the nucleus:
a) FSH b) TSH
c) calcitonin d) thyroxin

13. Thyroid hormones and catecholamines are derived from:

a) alcohol b) cholesterol
c) tryptofan d) tyrosine
e) glycine

14. The precursor for steroid hormones is:

a) alcohol b) cholesterol
c) hyroxy cholesterol d) hyroxy steroids
e) lipids

15. It does not match others in the list:

a) FSH b) estrogen
c) progesterone d) testosterone
e) aldosterone
16. Growth hormone:
a) double polypeptide
b) glycoprotein
c) requires insulin for its growth promoting action
d) requires IGF for its growth promoting action
e) decreases gluconeogenesis

17. The concentration of with hormone will increase if the hypothalamus is

damaged:
a) ACTH b) FSH
c) TSH d) LH
e) prolactin

12 D
13 D 14 B 15 A
16 D 17 E

Endocrinology MCQs 4 Dr. Sajid Ali Talpur

18. All of the following hormones are anabolic to protein metabolism except:
a) growth hormone
b) thyroid hormones in small physiological doses
c) insulin
d) cortisol in extra hepatic tissues
e) testosterone

19. All of the following hormones have their actions on mammary gland
except:
a) estrogen b) progesterone
c) prolactin d) growth hormone
e) LH

20.Milk ejection during suckling is caused by:

a) prolactin b) LH
c) oxytocin d) progesterone
e) somatomammotroph

21. It has receptors on cell membrane

a) T3 b) T4
c) TSH d) aldosterone
e) testosterone

22.Testosterone formation in the adults is stimulated by:

a) FSH b) LH
c) growth hormone d) inhibin
e) N.O.T

23.It is indispensable for the ovulation to occur

a) FSH b) LH
c) prolactin d) estrogen
e) progesterone

18 D
19 E 20 C 21 C
22 B 23 B

Endocrinology MCQs 5 Dr. Sajid Ali Talpur

24.ADH and oxytocin require _______ for their transport from
hypothalamus to posterior pituitary.
a) albumin b) globulin
c) plasma proteins d) neurophysin
e) freely in water

25.ADH:
a) acts on collecting duct to reabsorb water
b) increases blood volume
c) relaxes smooth muscles
d) released from posterior pituitary
e) increases intracellular Ca++ concentration

26.Growth hormone:
a) increases bone growth b) decreases TG synthesis
c) increases protein synthesis d) decreases intestinal Ca++ absorption
e) increases blood glucose

27.It is known as love hormone:

a) oxytocin b) estrogen
c) progesterone d) prolactin
e) LH

28.Thyroid glands contain large quantities of a protein called:

a) thyroprotein b) thyroalbumin
c) thyroglobulin d) thyrotyrosine
e) thyroprealbumin

29.All are necessary for the formation of thyroid hormones except:

a) iodide trapping b) coupling of iodotyrosines
c) iodination of tyrosine d) reduction of iodide
e) thyroperoxidase

24 D
25 C 26 D 27 A
28 C 29 D

Endocrinology MCQs 6 Dr. Sajid Ali Talpur

30.The most powerful and active thyroid hormone is:
a) T3 b) T4
c) reverse T3 d) TSH
e) calcitonin

31. All of the following hormones are hyperglycemic except:

a) growth hormone b) glucagon
c) cortisol d) thyroid hormones
e) ACTH

32.Parathormone:
a) increases PO4 level b) decreases Ca++ level
c) increases P absorption d) decreases Ca++ excretion
e) increases osteoblastic activity

33.Find the incorrect statement:

a) ANP is secreted from kidneys
b) ACTH stimulates cortisol
c) aldosterone secretion is stimulated by potassium an aldosterone
d) corticotropin releasing hormone is secreted from hypothalamus
e) N.O.T

34.A patient comes to doctor with low blood pressure and polyuria. He needs
the administration of:
a) mineralocorticoids b) glucocorticoids
c) ADH c) insulin
e) ACTH

35.Insulin receptors consist of:

a) α-chain b) β-chain
c) α & β chains d) 1 α & 2 β chains
e) 2 α & 2 β chains

30 A
31 E 32 D 33 A
34 C 35 E

Endocrinology MCQs 7 Dr. Sajid Ali Talpur

36.Insulin:
a) acts through tyrosine kinase pathway
b) can be taken orally in case of diabetes mellitus.
c) has half life of about 6 min.
d) is secreted by β cells of pancreas
e) is hypoglycemic hormone

37.Insulin increases all of the followings except:

a) protein synthesis b) TG synthesis
c) glycogenesis d) gluconeogenesis
e) convertion of pyruvate to acetyl CoA

38.Glucagon increases:
a) glycogenesis b) TG synthesis
c) excretion of glucose d) protein synthesis
e) force of contraction of heart

39.The major free circulating adrenocorticoid hormone in human is:

a) aldosterone b) cortisol
c) corticosterone d) androgens
e) cortisone

40.All of the following hormones release androgens except:

a) adrenal gland b) testis
c) ovary d) mammary gland
e) placenta

41. Total amino acids in insulin molecule are:

a) 49 b) 50
c) 51 d) 52
e) 55

36 B
37 D 38 E 39 B
40 D 41 C

Endocrinology MCQs 8 Dr. Sajid Ali Talpur

42.Find the incorrect statement:
a) hypothalamus is endocrine gland
b) GIT wall is exocrine
c) pancreas is endocrine as well as exocrine
d) liver is exocrine gland
e) parotid is exocrine gland

43.Aldosterone:
a) is secreted from zona glomerulosa
b) increases blood volume
c) antagonizes the effect of ANP
d) increases reabsorption of chlorides
e) increases K+ absorption

44.The main cause of baldness in men is:

a) cholesterol b) testosterone
c) vitamin deficiency d) thyroid hormones
e) cortisol

45.Catecholamines:
a) Ca++ acts as second messenger on binding with β receptors
b) c-AMP acts as second messenger on binding with α receptors
c) nor epinephrine is chiefly synthesized by adrenal medulla
d) epinephrine inhibits insulin release
e) in muscles epinephrine causes glycogenesis

46.The immediate precursor of testosterone is:

a) cholesterol b) pregnenolone
c) androstenedione d) progesterone
e) 17-hydroxyprogesterone

42 B
43 E 44 B 45 D
46 C

Endocrinology MCQs 9 Dr. Sajid Ali Talpur

47.Estrogen
a) increases the size of female genital organs
b) the most active form is β estradiol
c) causes appearance of secondary sexual characters
d) used as contraceptive
e) causes development of alveolar system of breasts

48.Progesterone:
a) secreted from ovary b) secreted from corpus luteum
c) causes menstruation d) causes changes in endometrium
e) the immediate precursor is pregnenolone

49.It causes contraction of gall bladder and emptying of bile

a) gastrin b) cholecystokinin
c) motilin d) secretin
e) GIP

50.After menopause there is increase in:

a) FSH b) LH
c) both a & b d) estrogen
e) progesterone

51. gonadotropic hormones are_______ in nature

a) glycoprotein b) protein
c) steroid d) amino acid derivatives

52.It uses phospholipase C pathway

a) oxytocin b) growth hormone
c) parathormone d) glucagon
e) ACTH

47 E 48 C
49 B 50 C 51 A
52 A

Endocrinology MCQs 10 Dr. Sajid Ali Talpur

53.Insulin increases:
a) gluconeogenesis b) amino acid formation
c) glycogenolysis d) lipolysis
e) glycogenesis

54.FSH secretion is inhibited by:

a) inhibin b) LH
c) progesterone d) somatostatin
e) dihydrotestosterone

55._______ increase the requirement of vitamins:

a) adrenal androgens b) testosterone
c) thyroid hormones c) parathormone
e) growth hormone

56.Kidneys secrete:
a) aldosterone b) angiotensin 1
c) angiotensin 2 d) renin
e) A.O.T

57.Cortisol:
a) decreases lipolysis
b) increases inflammation
c) decreases permeability of capillary membrane
d) increases extra hepatic protein synthesis
e) decreases stability of lysosomal membrane

58.A patient comes to doctor suffering from leg trauma and excess
inflammation. He needs the administration of:
a) growth hormone b) glucagon
c) insulin d) cortisol
e) aldosterone

53 E 54 A
55 C 56 D 57 C
58 D

Endocrinology MCQs 11 Dr. Sajid Ali Talpur

59.Antimullerian hormone is secreted by:
a) interstitial cells of leydig b) GIT wall
c) ovary d) sustenticular cells of sertoli
e) prostate gland

60.Pregnancy test is based on the presence of ______ in urine

a) FSH b) LH
c) HCG d) estrogen
e) progesterone

61. All are the stimulus for glucagon secretion except:

a) stress b) hypoglycemia
c) starvation d) exercise
e) somatostatin

62.Find the incorrect statement:

a) glucagon does not affect muscles
b) seminal vesicles are exocrine glands
c) TSH converts columnar thyroid cells to cuboidal
d) The number of receptors vary within minutes
e) Growth hormone increases insulin secretion

 Questions 63 – 80

 Select from the terms below:

A) Acromegaly B) Addison’s disease

C) Conn’s syndrome D) Adrenogenital syndrome
E) Cushing’s syndrome F) Diabetes insipidus
G) Goiter H) Hypothyroidism
I) Hyperthyroidism J) Cretinism
K) Osteoporosis L) Panhypopituitarism
M) Type 1 diabetes N) Type 2 diabetes
O) N.O.T

63.The enlargement of thyroid gland

Endocrinology MCQs 12 Dr. Sajid Ali Talpur

64.Loss of function of vasopressin

65.Characterized by hyperkalemia

66.Growth hormone deficiency in children

67.Excess growth hormone in adults

68.Tumors of zona glomerulasa cause

69.Administration of insulin is the treatment

70.Characterized by myxedema, cold intolerance

71. Characterized by torso buffalo

72.Lack of thyroid hormones during childhood

73.Characterized by thickening of hands, feet, protrusion of jaws but the

height remains normal

74.Total lack of posterior pituitary hormones

75.Old age disease due to the Vitamin C and estrogen deficiency

76.Insulin resistance by the target cells

77.TSH is elevated.

78.Excess cortisol

79.In pre pubertal males causes enlargement of sex organs

80.Characterized by somnolence.

Answer Key

1 E 2 C 3 B

Endocrinology MCQs 13 Dr. Sajid Ali Talpur

4 C 5 D 6 C
7 C 8 C 9 A
10 A 11 B 12 D
13 D 14 B 15 A
16 D 17 E 18 D
19 E 20 C 21 C
22 B 23 B 24 D
25 C 26 D 27 A
28 C 29 D 30 A
31 E 32 D 33 A
34 C 35 E 36 B
37 D 38 E 39 B
40 D 41 C 42 B
43 E 44 B 45 D
46 C 47 E 48 C
49 B 50 C 51 A
52 A 53 E 54 A
55 C 56 D 57 C
58 D 59 D 60 C
61 E 62 C 63 G
64 F 65 B 66 O
67 A 68 C 69 M
70 H 71 E 72 J
73 A 74 O 75 K
76 N 77 H 78 E
79 D 80 H

By the same Author:

Textbook References:
• MN Chatterjea, Rana Shinde. Textbook of Medical Biochemistry, 7th Edition,
2011.
• Guyton and Hall. Textbook of Medical Physiology, 12th Edition, SAUNDERS
ELSEVIER.
• Images from google.

Endocrinology MCQs 14 Dr. Sajid Ali Talpur