*********************************************************************************;

* Program Name: T-hosp-all.sas *

options mprint nofmterr missing='' ls=&ls ps=&ps;

options minoperator mindelimiter=',' noquotelenmax;

*******************************************************************************;
*** Read in ADSL ADHOSP ADAE Dataset ***;
*******************************************************************************;

proc datasets lib=work nolist kill; run;

%xudata1(adsl adhosp adae , libref =adam, select= where saffl='Y');

PROC SQL;
select distinct dcutdt into: dcutdt
from adsl;
quit;

%put &dcutdt;

data hosp;
merge adsl(in=a) adhosp(in=b);
by usubjid;
if a and b;
run;

proc sort data=hosp; by usubjid hostdt hoendt; run;

data firsthosp;
set hosp;
by usubjid hostdt;
if first.usubjid;
run;

***dataset for 2nd section***;

proc sort data=hosp out=hosp1;by usubjid hostdt hoendt;run;

data hosp2;
set hosp1;
by usubjid hostdt;
if first.usubjid then seq=1;
else seq+1;
if last.usubjid;

length seqcat $200;***making category 1 or >1, for using later for counting***;
if seq=1 then seqcat='Patients with 1 hospitalization';
else if seq>1 then seqcat='Patients with >1 hospitalizations';
run;

***dataset for 3rd section***;

data durcat;
set firsthosp;
by usubjid hostdt hoendt;
length durcat $200;format hostdt1 hostdt2 hostdt3 hostdt4 hostdt5 date9.;
retain hostdt1 hostdt2 hostdt3 hostdt4 hostdt5;

hostdt1=trtsdt+30.4375-1;
hostdt2=(hostdt1+30.4375);
hostdt3=(hostdt2+30.4375);
hostdt4=(hostdt3+30.4375);
hostdt5=(hostdt4+30.4375);
hostdt6=(hostdt5+30.4375);

if hostdt<trtsdt then do;durcat=' Prior to Day 1';durcatn=1;end;

else if (hostdt>=trtsdt and hostdt<=hostdt1) then do;durcat=' During month
1';durcatn=2;end;
else if (hostdt>hostdt1 and hostdt<=hostdt2) then do;durcat=' During month
2';durcatn=3;end;
else if (hostdt>hostdt2 and hostdt<=hostdt3) then do;durcat=' During month
3';durcatn=4;end;
else if (hostdt>hostdt3 and hostdt<=hostdt4) then do;durcat=' During month
4';durcatn=5;end;
else if (hostdt>hostdt4 and hostdt<=hostdt5) then do;durcat=' During month
5';durcatn=6;end;
else if (hostdt>hostdt5 and hostdt<=hostdt6) then do;durcat=' During month
6';durcatn=7;end;
else if hostdt>hostdt6 then do;durcat=' After month 6';durcatn=8;end;
run;

data alivestay_;
merge hosp1(in=a) adsl(in=b);
if a and b;
by usubjid;
run;
proc sort nodupkey;by usubjid;run;

data alivestay;
set alivestay_;
dthdt_= dthdt; trtsdt_= trtsdt;
if DTHDT_ ne . and TRTSDT_ <= DTHDT_ <= TRTSDT_+89 then alive_stay= DTHDT_ -
TRTSDT_ +1;
Else alive_stay= 90;
run;

******Macro for overlapping days count****;

proc sort data =hosp1;by usubjid hostdt hoendt;run;

data hosp11;
set hosp1;
if hostdt<trtsdt then hostdt=trtsdt;
if hostdt >=trtsdt;
if hoendt=. then hoendt='18mar2021'd;
run;

data Totdays;
set hosp11;
run;

data d190_;
set hosp1/*(rename=(trta=trt01a trtan=trt01an))*/;
if hoendt ne . then do;
if hostdy>90 or hoendt < trtsdt then delete;****hosp starts after day90, deleted**;
end;
if hostdt<trtsdt then hostdt=trtsdt;
***resetting hosp start date if before Day 1, hosp count only from trtsdt****;
if hoendt>(trtsdt+89) then hoendt=trtsdt+89;****keeping enddate as upto D90 days**;
/*keep usubjid hostdt hoendt trt01a trt01an;*/
run;

data d190;
set d190_;
if hostdt<trtsdt then hostdt=trtsdt;
if hostdt >=trtsdt;
if hoendt=. then hoendt='18mar2021'd;
if hoendt>(trtsdt+89) then hoendt=trtsdt+89;
run;

data chk_;
set hosp1/*(rename=(trta=trt01a trtan=trt01an))*/;
where hostdy >=1 ;
keep usubjid hostdt hoendt trt01a trt01an trtsdt;
run;

data chk;
set chk_;
if hostdt<trtsdt then hostdt=trtsdt;
if hostdt >=trtsdt;
if hoendt=. then hoendt='18mar2021'd;
if hoendt>(trtsdt+89) then hoendt=trtsdt+89;
run;

data excludeaza_;
set hosp1/*(rename=(trta=trt01a trtan=trt01an))*/;
where ^(INDEX(HORESP,'AZA')>0 OR INDEX(HORESP,'Aza')>0);
/* keep usubjid hostdt hoendt trt01a trt01an horesp trtsdt;*/
run;

data excludeaza;
set excludeaza_;
if hostdt<trtsdt then hostdt=trtsdt;
if hostdt >=trtsdt;
if hoendt=. then hoendt='18mar2021'd;
if hoendt>(trtsdt+89) then hoendt=trtsdt+89;
run;

%macro hospital_eoh(dataset_in=,dataset_out=);
/* Step 1 - Number the sorted data for EoH */
data data_1;
set &dataset_in;
by usubjid hostdt hoendt;
retain n;
if first.usubjid then n=0;
n=n+1;
run;
/* Step 2 - Transpose the variables in hostdt and hoendt for EoH */
%macro eoh(inA=,inB=,outA=,from=,to=);
proc transpose data=&inA out=&outA (drop=_name_) prefix=&to;
by usubjid;
var &from;
run;
%mend;
%eoh(inA=data_1,outA=admit,from=hostdt,to=hostdt)
%eoh(inA=data_1,outA=dschg,from=hoendt,to=hoendt)
/* Step 3 - Combine the transposed admission & discharged date & main files */
%macro join(inA=, inB=, outA=, b=, xvar=);
data &outA;
merge &inA (in=x) &inB (in=y drop=&xvar);
by &b;
if x and y; run;
%mend;
%join(inA=admit, inB=dschg, outA=Admit_dschg, b=usubjid)
%join(inA=data_1, inB=Admit_dschg, outA=hospital_adm_dschg, b=usubjid)
proc sql;
select left(trim(put(MAX(count),5.))) into: Idy from
(select count(*) as count
from hospital_adm_dschg
group by usubjid);
QUIT;
%PUT &Idy;
proc sort data=hospital_adm_dschg;
by usubjid hostdt hoendt;
run;
/* Step 4 - Compute and assign EoH & Hospitalization Types */
data data_2 (drop= i diff done eoh2 seq2 hostdt1-hostdt&Idy hoendt1-
hoendt&Idy);
set hospital_adm_dschg;
by usubjid hostdt hoendt;
where n LE &Idy;

los = hoendt - hostdt + 1;

array adm (*) hostdt1-hostdt&Idy;
array dcg (*) hoendt1-hoendt&Idy;
retain eoh2 seq2; done=0;
if first.usubjid then do;
eoh1=0; eoh2=eoh1; seq=0; seq2=seq; nest=0; trans=0;
end;
if n = 1 then do;
eoh1=1; eoh2=eoh1; seq=1; seq2=seq; nest=0; trans=0;
if adm(2) ^= . AND adm(1) >= adm(2) and dcg(1) < dcg(2) then do;
eoh1=eoh2; seq=seq2; eoh2=eoh1; seq2=seq; nest=1; trans=0;
end;
end;
else if n = 2 then
do;
if 0 <= abs(adm(2)-dcg(1)) <= 1 and (dcg(2) > dcg(1) or
(dcg(2) = dcg(1))) then do;
eoh1=eoh2; seq=seq2+1; eoh2=eoh1; seq2=seq; nest=0;
trans=1;
end;
else if adm(2) >= adm(1) and (dcg(2) < dcg(1) or
(dcg(2) = dcg(1))) then do;
eoh1=eoh2; seq=seq2; eoh1=eoh2; seq=seq2; nest=1; trans=0;
end;
else if adm(3) ^= . AND adm(2) >= adm(3) and dcg(2) < dcg(3) then do;
eoh1=eoh2; seq=seq2; eoh2=eoh1; seq2=seq; nest=1; trans=0;
end;
else do;
eoh1=eoh2+1; seq=seq2; eoh2=eoh1; seq2=seq; nest=0; trans=0;
end;
 end;
else if n > 2 then do;
do i=1 to n-1;
diff=abs(adm(n)-dcg(i));
if 0 <= abs(adm(n)-dcg(i)) <= 1 and
((dcg(n) > dcg(i) or dcg(n) = dcg(i))) then do;
eoh1=eoh2; seq=seq2+1; eoh2=eoh1; seq2=seq; nest=0;
trans=1; done=1;
leave;
end;
end;
do i=1 to n-1;
if not(done) and adm(n) >= adm(i) and (dcg(n) < dcg(i) or
(dcg(n)=dcg(i))) then do;
eoh1=eoh2; seq=seq2; eoh1=eoh2; seq=seq2; nest=1; trans=0;
done=1;
leave;
end;
end;
do i=1 to n-1;
if not(done) and abs(adm(n) - dcg(i)) > 1 then do;
done=1; seq=1; seq2=seq; eoh1=eoh2+1; eoh2=eoh1; nest=0;
trans=0;
leave;
end;
end;
if (n + 1) LE &Idy AND adm(n+1) ^= . and adm(n) >= adm(n+1) and dcg(n) <
dcg(n+1) then do;
eoh1=eoh2; seq=seq2; eoh2=eoh1; seq2=seq; nest=1; trans=0; done=1;
END;
end;

run;
proc sort data=data_2;
by usubjid eoh1 hostdt hoendt;
run;
/* Step 5 - Compute other variables (i.e. LOS) & prepare the final output */
DATA data_3; retain usubjid hostdt hoendt n eoh1 count nest trans los
/*EOH_LOS*/; SET data_2;
by usubjid eoh1 hostdt hoendt;
RETAIN count; count + 1;
IF FIRST.eoh1 THEN count = 1;
rename eoh1 = eoh;
rename n = total_hosp;
rename los = hosp_los;
drop seq;
run;
data data_nonest;
set data_3;
IF nest ^= 1;
run;
DATA data_4;
SET data_nonest;
BY usubjid EOH;
IF FIRST.EOH OR LAST.EOH;
hoendt_first = lag(hoendt);
hostdt_first = lag(hostdt);
usubjid_first = lag(usubjid);
EOH_first = lag(EOH);
 IF usubjid = usubjid_first AND EOH = EOH_first THEN hostdt = hostdt_first;
IF LAST.eoh;
eoh_los = hoendt - hostdt + 1;
format hostdt hoendt date9.;
KEEP usubjid EOH eoh_los count;
RUN;
PROC SQL;
CREATE TABLE &dataset_out AS
SELECT a.*, b.eoh_los
FROM data_3 a LEFT JOIN data_4 b
ON a.usubjid = b.usubjid AND a.eoh = b.eoh
ORDER BY usubjid, EOH, hostdt, hoendt;
QUIT;
%mend hospital_eoh;

%hospital_eoh(dataset_in=Totdays,dataset_out=Totdays1)
%hospital_eoh(dataset_in=d190,dataset_out=d190out)
%hospital_eoh(dataset_in=chk,dataset_out=chk1)
%hospital_eoh(dataset_in=excludeaza,dataset_out=excludeazaout)

data exclude_beforeday1;
set chk1;
if count=1 and eoh_los>=1;
run;

data excludeazaout1;
set excludeazaout;
if count=1 and eoh_los>=1;
run;

data d190out1;
set d190out;
if count=1 and eoh_los>=1;
run;

data Totdayshosp;
set Totdays1;
if count=1 and eoh_los>=1;
run;

proc sql;
create table d190cnt as
select trt01an, trt01a, 5 as section, 20.5 as sord,
' day1-90' as text length=200,sum(eoh_los) as numer
from d190out1
group by trt01an, trt01a, section, sord, text;
quit;

proc sql;
create table alivecnt as
select trt01an, trt01a, 5 as section, 20.5 as sord,
'Total days alive during day 1 - day 90' as text length=200,sum(alive_stay) as
denom
from alivestay
where alive_stay ne . /*and durcatn in(2,3,4)*/
group by trt01an, trt01a, section, sord, text;
quit;
data aliveprcnt;
merge alivecnt(in=a) d190cnt(in=b);
format per 5.1;
by trt01a trt01an;
if a and b;
per= (numer/denom)*100;
run;

data hosp3;
length daysdur $40.;
set hosp11;
by usubjid hostdt hoendt;

hoendt_original=hoendt;/*keeping original dates before chaging***/

hostdt_original=hostdt;

****for section 6 Number of patients with >=1 hospitalization duration of

categories***;
hosp_stay_cat=hoendt_original - hostdt_original + 1;**for category purpose, using
original hoendt value***;

if hosp_stay_cat>=1 and hosp_stay_cat<=6 then do;daysdur='1 - 6

days';daysdurn=1;end;
if hosp_stay_cat>=7 and hosp_stay_cat<=13 then do;daysdur='7 - 13
days';daysdurn=2;end;
if hosp_stay_cat>=14 and hosp_stay_cat<=20 then do;daysdur='14 - 20
days';daysdurn=3;end;
if .<hosp_stay_cat>=21 then do;daysdur='~{unicode 2265} 21 days';daysdurn=4;end;

****for section 8 Time to Start of First Hospitalization (days)***;

if first.usubjid then tth=1;***only for First Time to hospitalization**;

/*keep usubjid hostdt hoendt trtsdt hostdy hoendy;*/

run;

data hosp33;
set hosp3;
if hoendt<hostdt then delete;
run;

/* 8 section*/

data firsthospdays;
set hosp3;
where tth=1;
firsthospdays=(hostdt-trtsdt)+1;
run;

proc sql noprint;

**scetion 1**;
create table counts as
select trt01an, trt01a, 1 as section, 10 as sord, 'Total number of hospitalized
patients' as text length=200,count(distinct usubjid) as smaln
from firsthosp
where hostdt ne .
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 1 as section, 11 as sord, ' First hospitalization began
before Day 1' as text length=200,count(distinct usubjid) as smaln
from firsthosp
where hostdt<trtsdt
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 1 as section, 12 as sord, ' First hospitalization began
on Day 1' as text length=200,count(distinct usubjid) as smaln
from firsthosp
where hostdt=trtsdt
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 1 as section, 13 as sord, ' First hospitalization began
after Day 1' as text length=200,count(distinct usubjid) as smaln
from firsthosp
where hostdt>trtsdt
group by trt01an, trt01a, section, sord, text

/*section 2*/
union
select trt01an, trt01a, 2 as section, 14 as sord, seqcat as text
length=200,count(distinct usubjid) as smaln
from hosp2
where seqcat>''
group by trt01an, trt01a, section, sord, text

/*section 3*/
union
select trt01an, trt01a, 3 as section, 15 as sord, durcat as text
length=200,count(distinct usubjid) as smaln
from durcat
where durcat>''
group by trt01an, trt01a, section, sord, text

/*section 4*/
union
select trt01an, trt01a, 4 as section, 16 as sord,
'Total days of hospitalization [1][2]' as text length=200,sum(eoh_los) as smaln
from totdayshosp
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 4 as section, 17 as sord,
' During day 1 - day 90' as text length=200,sum(eoh_los) as smaln
from d190out1
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 4 as section, 18 as sord,
' Subgroup excluding any stay began before day 1' as text
length=200,sum(eoh_los) as smaln
from exclude_beforeday1
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 4 as section, 19 as sord,
' Subgroup excluding Azacitidine dosing' as text length=200,sum(eoh_los) as
smaln
from excludeazaout1
group by trt01an, trt01a, section, sord, text

/*section 5*/
union
select trt01an, trt01a, 5 as section, 20 as sord, 'Total days alive during day 1 -
day 90' as text length=200,sum(alive_stay) as smaln
from alivestay
where alive_stay ne . /*and durcatn in(2,3,4)*/
group by trt01an, trt01a, section, sord, text

union
select trt01an, trt01a, 5 as section, 20.5 as sord, 'Hospital days per days alive
during day 1 - day 90 (%) [1][2][3]'
as text length=200,per as smaln
from aliveprcnt
group by trt01an, trt01a, section, sord, text

/*section 6*/
union
select trt01an, trt01a, 6 as section, 21 as sord,' '||strip(daysdur) as text
length=200,count(distinct usubjid) as smaln
from hosp3
where daysdur>''
group by trt01an, trt01a, section, sord, text

/*Section 7, unique n counts*/

union
select trt01an, trt01a, 7 as section, 22 as sord,'n' as text length=200,
count(distinct usubjid) as smaln
from hosp33
where hosp_stay_cat ne .
group by trt01an, trt01a, section, sord, text

/*Section 8, unique n counts*/

union
select trt01an, trt01a, 8 as section, 24 as sord,'n' as text length=200,
count(distinct usubjid) as smaln
from hosp3
where tth ne .
group by trt01an, trt01a, section, sord, text;

quit;

proc sql noprint;

create table header as
select trt01an, trt01a, count(distinct usubjid) as denom
from adsl
where trt01an ne . and saffl='Y'
group by trt01an,trt01a;

select denom into:n1-:n2

from header;
quit;

%put &n1 &n2;

data counts2;
merge counts header;
by trt01an trt01a;

length perc $50;

if section not in(4,5,7,8) then do;
if nmiss(smaln,denom)= 0 then perc=put(smaln, 3.)||put("
("||strip(put((smaln/denom)*100,5.1))||")",8. -r);
end;

if perc='' and sord ne 20.5 then perc=put(smaln,8.);

if perc='' and sord eq 20.5 then perc=put(smaln,9.1);
run;

proc sort data=counts2;by section sord text;

run;

proc transpose data=counts2 out=t_cnt prefix=trt;

by section sord text;
var perc;
id trt01an;
run;

****Section 7 for mean, median, min, max stats*******************************;

data hosp33;
set hosp3;
if hoendt<hostdt then delete;
run;
proc sort data=hosp33;by trt01an trt01a;run;
proc means data=hosp33 noprint min max median std mean;
by trt01an trt01a;
var hosp_stay_cat;

output out=duration(drop=_type_ _freq_) mean=mn stddev=sd median=md min=min max=max

/ autoname;
run;

****Section 8 for mean, median, min, max stats*******************************;

proc sort data=firsthospdays;by trt01an trt01a;run;
proc means data=firsthospdays noprint min max median std mean;
where tth ne .;
by trt01an trt01a;
var firsthospdays;

output out=tth_stat(drop=_type_ _freq_) mean=mn stddev=sd median=md min=min max=max

/ autoname;
run;

data duration;
set duration;
section=7;sord=23;
run;

data tth2;
set tth_stat;
section=8;sord=25;
run;

data section78;
merge duration tth2 ;
by section sord;
run;

data step1(drop=mn sd md min max);

set section78;
*n1=(put(n, 8.));
if not missing(mn) and not missing(sd) then
mn1=(put(mn,10.1)||' ('||strip(put(sd, 9.2)))||')';
if not missing(mn) and missing(sd) then
mn1=(put(mn, 10.1)||' (NE)');
if missing(mn) and missing(sd) then mn1=(put('NE',2.)||' (NE)');

md1=(put(md, 10.1));
if missing(md) then md1=put('NE',4.);

if not missing(min) and not missing(max) then

/*minmax=(put(min,best.)||', '||strip((put(max,best.))));*/
minmax=(put(min, 9.0)||', '||strip((put(max, 9.0))));

if missing(min) and missing(max) then minmax=right(put('NE ,NE',7.));

run;

proc sort data=step1;by section sord;

run;

*transposing data;
proc transpose data=step1 out=t_step1(rename=(_name_=text)) prefix=TRT ;
by section sord;
id trt01an;
var mn1 md1 minmax;
run;
proc sort;by section sord text;run;

data allset1;
merge t_cnt t_step1;
by section sord text;
run;
****Creating the frame of texts*******;

data frame;
length text $200;

section=3;sord=14.9;text='Number of patients with first hospitalization

starting:';output;
section=6;sord=20.9;text='Number of patients with days of hospitalization of[1][2]:
';output;
section=7;sord=21.9;text='Days of hospitalization (days) [1][2]';output;
section=8;sord=23.9;text='Time to start of first hospitalization (days)[2]';output;

run;

data allset2;
merge allset1 frame;
by section sord text;

if section=3 and sord=15 then do;

if text=' During month 1' then subord=.1;
else if text=' During month 2' then subord=.2;
else if text=' During month 3' then subord=.3;
else if text=' During month 4' then subord=.4;
else if text=' During month 5' then subord=.5;
else if text=' During month 6' then subord=.6;
else if text=' After month 6' then subord=.7;
else if text=' Prior to Day 1' then subord=.01;
end;
if section=6 and sord=21 then do;
if text=' 1 - 6 days' then subord=.1;
else if text=' 7 - 13 days' then subord=.2;
else if text=' 14 - 20 days' then subord=.3;
else if text=' ~{unicode 2265} 21 days' then subord=.4;
end;
if section in(7,8) then do;
if text='n' then do; text=' n';subord=.1;end;
else if text='mn1' then do; text=' Mean (SD)';subord=.2;end;
else if text='md1' then do; text=' Median';subord=.3;end;
else if text='minmax' then do; text=' Min, Max';subord=.4;end;

end;

if subord ne . then sord+subord;

run;

proc sort data=allset2;by section sord text;run;

data dummy;
length text $200 ;

text=' First hospitalization began before Day 1';sord=11;section=1;_name_ =

'perc';output;
text='Patients with >1 hospitalizations';; sord=14;section=2;_name_ =
'perc';output;
text=' During month 1' ; sord=15.1;section=3;_name_ = 'perc';output;
text=' During month 2' ; sord=15.2;section=3;_name_ = 'perc';output;
text=' During month 3' ; sord=15.3;section=3;_name_ = 'perc';output;
text=' During month 4' ; sord=15.4;section=3;_name_ = 'perc';output;
text=' During month 5' ; sord=15.5;section=3;_name_ = 'perc';output;
text=' During month 6' ; sord=15.6;section=3;_name_ = 'perc';output;
text=' After month 6' ; sord=15.7;section=3;_name_ = 'perc';output;
text=' Prior to Day 1' ; sord=15.01;section=3;_name_ = 'perc';output;

text=' 1 - 6 days' ; sord=21.1;section=6;_name_ = 'perc';output;

text=' 7 - 13 days' ; sord=21.2;section=6;_name_ = 'perc';output;
text=' 14 - 20 days' ; sord=21.3;section=6;_name_ = 'perc';output;;
/* text=' 11 - 13 days' ; sord=21.4;section=6;_name_ = 'perc';output;*/
/* text=' 14 - 20 days' ; sord=21.5;section=6;_name_ = 'perc';output;*/
/* text=' 21 - 27 days' ; sord=21.6;section=6;_name_ = 'perc';output;*/
text=' ~{unicode 2265} 21 days' ; sord=21.4;section=6;_name_ = 'perc';output;
proc sort;by sord text;
run;
proc sort data=allset2;by sord text;run;
data allset2_;
merge allset2 dummy;
by sord text;
run;;

proc sort data=allset2_;by section sord text;

run;

data result(rename=(_name_= name));

set allset2_ ;

by section sord text;

*trt1=strip(trt1);
*trt2=strip(trt2);

if section in(1,2,3) then pg=1;

else if section in(4,5,6) then pg=2;
else pg=3;
run;

data result_;
set result;
array nn trt:;
do over nn;
if NAME = 'perc' and nn = '' then nn = strip(put(0, 9. -r));;
end;
run;

DATA _NULL_;
CALL SYMPUT("FDATE",LEFT(PUT("&sysdate."d,YYMMDDN8.)));

RUN;

%xurtfsty();

ods rtf close;

options orientation=landscape nofmterr;
ods escapechar = '~';

%xurtfpt4(1, libref=tables);

%jprntd1(result_,t14_3_7_1_Hosp_all_SAS, %str( trt: text section sord),

%str(section sord pg), seq=1);

data _null_;
length lstfootl1 lstfootr1 lstfootl2 lstfootr2 $ 200;
lstfootl1="Source: Listing 16.3.7.1";
lstfootr1 = "Data Cutoff Date: &dcutdt.";
lstfootl2="Program Name:
/&CLNT./&PROJ./&TASK./%sysget(TASKDIR)/programs/tables/&SYSPARM..sas";
lstfootr2="Run Date: &sysdate9.(&SYSTIME)";

underln = repeat('_',161);
call symput('lstfootl1',lstfootl1);
call symput('lstfootr1',lstfootr1);
call symput('lstfootl2',lstfootl2);
call symput('lstfootr2',lstfootr2);
call symput('underln',underln);
 run;

%jcgpgs1(9, pagesize_out, noheadskip=);

proc report data = result_ headskip headline split='|' nowd ls=161 ps=&ps. missing
spacing=2;
column pg section sord text trt1 trt2;

define pg / order noprint;

define section / order noprint;
define sord/ order order=internal noprint;

define text / /*order*/ flow " " style(header)=[just=left]

style(column)=[protectspecialchars=off cellwidth=2.0 in asis=on
just=left] width=52;

define trt1 / "AG-120+azacitidine|N=%left(&n1) " flow

style(header)=[just=c] style(column)=[protectspecialchars=off
cellwidth=0.75 in asis=on just=c] width=14;
define trt2 / "Placebo+azacitidine|N=%left(&n2) " flow
style(header)=[just=c] style(column)=[protectspecialchars=off
cellwidth=0.75 in asis=on just=c] width=14;

compute before section /style=[protectspecialchars=off asis=on just=left];

line @0 " " ;
endcomp;

break after pg / page;

footnote1 j=l h=9pt "&underln.";

footnote2 j=l h=9pt "The denominator used to calculate percentages is N, the
number of Subjects in the safety analysis set within each column.";
footnote3 j=l h=9pt "Only hospitalization days on or after day 1 are included in
the analysis. ";
footnote4 j=l h=9pt "[1] Days of hospitalization of each patient = total number
of days spent in the hospital from all hospital stays for each patient. For
patients with multiple hospital stays, only the non-overlapping days are counted.
Total days of hospitalization = sum of total days of hospitalization for all
patients.";
footnote5 j=l h=9pt "[2] Only hospitalization days on or after day 1 are
included in the analysis. Hospital stays started before day 1 will have day 1 as
hospitalization start date. Ongoing hospital stays will have data cut-off date as
hospitalization end date. ";
footnote6 j=l h=9pt "[3] Hospital days per days alive during day 1 - day 90 =
(Total days of hospitalization during day 1 - day 90)/(Total days alive during day
1 - day 90) * 100.";
footnote7 j=l h=9pt "&lstfootl1." j=r "&lstfootr1.";
footnote8 j=l h=9pt "&lstfootl2." j=r "&lstfootr2.";

run;

ods rtf close;

ods listing;

%xurtfpt4;

title;
footnote;