Human Reproduction
Human Reproduction
Human Reproduction
Ureter Urinary
bladder
Vas deferens
Seminal
vesicle
Prostate
-Bulbourethral
gland
Epididymis
-Urethra
Vasa efferentia
Rete testis
LForeskin
Glans penls
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a. Primary sex organs (Paired testes)
Epididymis
Vas efferentia
Rete testis
Seminiferous
tubules Vas deferens
Testicular
labule
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" Supplies nutrients to sperms.
P'rovides alkalinity to counteract the acidity of uterus.
" Secretions of Cowper's glands lubricate the penis. & prostate help for
maturation
seminal vesicle
Secretions of epididymis, vas deferens,
nd motility of sperms.
d. Penis (externalgenitalia)
II is a copulatory organ made of erectile spongy tissue. inseminaton.
Spongy tissue is filled with blood. the penis erects. It facilitates
nen prepuce
cone-shaped tip of the penis is called glans penis. It is covered by
The
(foreskin). 2.Female Reproductive System
of Ovaries).Accessory ducts, Accessory
t ncludes Primary sex organ (a pair
glands and External genitalia.
a Primary sex organ (Paired ovaries)
(fermale gamete) & steroid ovarian
mary Sex organs which produce ova
hormones (estrogen &progesterone).
Ovaries are located on both side of the lower abdomen.
the pelvic wall and uterus by
Each ovary is 2-4 cm in length and is connected to
ligaments.
which encloses the ovarian stroma.
tdcn oary is covered bya thin epithelium
The stroma has outer cortex and inner medulla. centrally
Ovary contains groups of cells (Ovarian follicles). Each follicle carries a
placed ovum.
Cortex
Corpus
4rtoum
Tunica Medulla
albuginea
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attached to the pelvi wall
Uterus has 3 parts Upper fundus, middle body and terminal cervIx. Cervix
opens to vagina.
The uterine wall has 3 layers such as
r External perimetrium (thin membrane).
Middle myometrium (thick layer of smooth muscle).
e Inner glandular and vascular endometrium.
Uterine fundus
Uerine cavity
Isthmus
-Ampulla Falloplan
tube
-Infundibulum
Endometrtum Ovary
Myometrdum Fimbriae
Pertmetrtum
Cervix
-Cervical canal
-Vagina
3. Vagina: It opens to the exterior between urethra &anus. The lumen of vagina is
lined by aglycogen-rich mucous membrane consisting of sensitive papillae and
Bartholin's glands. The secretions of Bartholin's glands lubricate the penis
during sexual act.
GAccessory glands
Bartholin's glands.
d External genitalia (vulva or pudendum)
Consist of Mons pubis, vestibule, hymen &clitoris.
Mons pubis: Acushion of fatty tissue covered by pubic hair.
Vestibule: A median channel. It includes
" Labia majora: Large, fleshy, fatty and hairy outer folds. Surrounds vaginal
opening.
" Labia minora: Small, thin and hairless inner folds.
" Hymen (Maiden head): A membrane which partially cover the vaginal opening. It
is often torn during the first coitus. It may also be broken by a sudden fall or jolt,
insertion of a vaginal tampon; active participation in some sports items etc. In
some wonen, hymen persists after coitus. So the hymen is not a reliable
indicator of virginity.
" Clitoris: Ahighly sensitive organ lying just in front of the urethral opening.
Mammary glands (breasts)
Apair of mammary glands contains glandular tissue &fat.
" Glandular tissue of each breast has 15-20 mammary lobes containing clusters of
cells (mammary alveoli).
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Cells of alveoli secrete milk. It is stored in lumen of alveoli.
The alveoli open into mammary tubules.
The tubules of each lobe join to form a mammary duct.
Several mammary ducts join to form a wider mammary ampulla which is
connccted to lactiferous duct through which milk is sucked out.
Fal
Mammary lobe
Mammary alveolus
Mammary duct
Ampulla RIE
Nipple
Pectoralls
Areola major muscle
GAMETOGENESIS
- It is the formation of gametes in the gonads.
It includes Spermatogenesis and Oogenesis.
1. Spermatogenesis
Schematic representation ofspermnatogenesis
Spermatogonia -2n (46 chromosomes)
Mitosis difjerentiation
Primary spematocytes (2n)
Jmeiotic division
Sec. spermatocytes -n (23)
| 2meiotic division
Spernatids (n)
|Diferentiation
Spermatozoa (n)
The spermatogonia (sing spermatogonium) present on the inside wall of seminiferous
tubules multiply by mitotic division and increase in numbers.
Each spermatogonium is diploid and contains 46 chromosomes. Some of the
spermatogonia called primary spermatocytes periodically undergo meiosis.
A primary spermatocyte completes the first meiotic division (reduction division)
leading to formation of two equal, haploid cells called secondary spermatocytes, which
have only 23 chromosomes each.
- The secondary spermatocytes undergo the second meiotic division to produce four
equal, haploid spermatids.
- The spermatids are transformed into spermatozoa (sperms) by the process called
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spermiogenesis.
After spermiogenesis, sperm heads become embedded in the Sertoli cells. Then they
are released to lumen of seminiferous tubules. It is called
spermiation.
Structure of spermatozoa (Sperm)
A mature sperm is about 60 u (0.06 mm) long.
Aplasma membrane envelops the whole body of sperm.
Sperm has 3 regions:
. Head: Oval shaped. Formed of nucleus and acrosome. Acrosome is formed from Golgi
complex. It contains lytic enzymes. Behind the head is a neck containing proximal
and distal centrioles.
b. Middle piece: Composed of axial filament surrounded by mitochondria and
cytoplasm. Mitochondria produce energy for the sperm motility.
c. Tail: Consists of a central axial filament. The sperm moves in fluid medium and
female genital tract by the undulating movement of the tail.
The human male ejaculates about 200-300 million sperms during a coitus.
For normal fertility at least 60% sperms must have normal shape and size. 40% of
them must show vigorous motility.
Plasna
membrane
Acrosone
Nucleus containing
Head
chron1OSOmal material
Neck
Middle ptece
Milochondria
(energy source for swimming)
map
DBCATON
Tall
Oogenesis is initiated in embryonic stage when millions of egg mother cells (oogonia)
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are formed within cach ovary.
added after birth.
No more oogonia are formed and
cnter into prophase-I of the meiosis
Oogonia multiply to forn primary oocytes. They
and get temporarily arrested at that stage.
a layer of granulosa cells to form
- Each primary o0cyte gets surrounded by
primary follicle.
Oogonla
Mitosis
differenttation
- A large number of primary follicles degenerate during the phase from birth to
puberty. Therefore at puberty only 60,000-80,000 primary follicles are left in each
ovary.
Primary follicles get surrounded by more layers of granulosa cels and a new theca to
form secondary follicles.
The secondary follicles transform into a tertiary follicle. It has a fluid filled cavity
(antrum). The theca layer forms an inner theca interna and an outer theca externa.
- The primary oocyte in the tertiary folicle grows in size and undergoes first unequal
meiotic division to form a large haploid secondary oocyte and a tiny first polar body.
The secondary oocyte retains the nutrient rich cytoplasm of the primary oocyte.
- It is unknown that whether the first polar body divides further or degenerates.
- The tertiary follicle further changes into the mature follicle (Graafian follicle).
- Secondary oocyte forms a new membrane (zona pellucida).
Graafian follicle now ruptures to release the secondary oocyte (ovum) from the
ovary. This is called ovulation.
Structure ofovum
Corona radiata
Zona pellucida
Vltelliae membrane
Nucleus
Germinal vessicle
(ytoplasm
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- Spherical and non-motile.
About 0.2 mm in diameter.
Ovum has 4 membranes:
a. Plasma membrane: Innermost layer.
b. Vitelline membrane: Attached to plasma
membrane.
c. Zona pellucida: Outer to the Vitelline membrane.
d. Corona radiata: Outer layer formed of follicle cells.
MENSTRUAL CYCLE (REPRODUCTIVE CYCLE)
- It is the cyclic events starting from one menstruation till the next
that take place
during the reproductive period (from puberty to menopause) of a woman's life.
- Its duration is 28 or 29 days.
Menstrual cycle is also seen in other primates.
- Menstrual cycle includes
a. Ovarian cycle: Changes in ovary.
b. Uterine cycle: Changes in uterus, oviduct and vagina.
Horm
FSH LH
events
Developlng Regressihg
OvarianDevelopng folllcle Mature follicle corpus luteum corpus luteum
levels
Ovulatton
Hormone
Estrogen
events Progesterone
Uterine
Menses
Days 13 15 17 19 21 23 25 27 29/1
13 11
Menstruatlon Follcular phase Luteal phase Next cycle
(Prollferattve phase) (Secretory phase) begins
DO ocY
Sperm
-Cells of the
corona radlata
Ovume
Zone
pelluctdn
Pertvitelllne apace
(b
(Monula)
Blastoyst
Implantation
(Blastocyst)
fallopian tube
Traneport of onum, lertilleation and pange of growtng embryo through
Cavity of
enus
vessels Embryo
lug of murus
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Changesin embryo during pregnancy
. After one month: Heart is formed.
. End of second month: Limbs and digits are developed.
" End of 12 weeks (irst trimester): The major organs (limbs, external genital organs etc.)
are well deyeloped.
During 5 month: First movement of foetus and appearance of hair on the
head.
" End of 24 weeks (second trimester): Body is covered with fine hair, eyelids separate
and eye lashes are formed.
" End of 9 months: Ready for delivery.
PARTURTION AND LACTATION
- Parturition (labour): Process of giving birth to young ones.
Parturition is induced by neuroendocrine mechanism.
- The signals originating from the foetus and placenta induce mild uterine contractions
(fetal ejection reflex). This causes the release of oxytocin from maternal pituitary.
Oxytocin causes stronger uterine muscle contractions which in turn stimulate further
secretion of oxytocin. This process is continued leading to expulsion of the baby out of
the uterus through the birth canal.
- After parturition, the umbilical cord is cut off.
The placenta &remnants of umbilical cord are expelled from the maternal body after
parturition. It is called "after birth".
The mammary glands produce milk towards the end of pregnancy. It is called
lactation.
The yellowish milk produced during the initial few days of lactation is caled colostrum.
It contains several antibodies essential to develop resistance for the new born babies.
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S) In women, sonme hormones are sereted only during pregnancy.
Name any such hormones.
6) LH and FSH play signiflcantrole in spermatogenesis'. [3)
a) Write the functions of LH and FSH in spermatogenesis.
b) Write a single tem used to denote Ll and FSH together.
SAY- 2020
7) The embvo vith 8 to l6 blastomeres is called a [1]
(a) Gastula (b) Morula
(O Blastula (d) Trophoblast
8) ReaTange the following human reproductive events in the correct order of their
OCCurTenCe: [2
Latation Formation of Zygote "Insemination Implantation
Fertilisation Gametogenesis Gestation »Parturition
9) Obseve the diagrammatic view of male reproductive system given below and name the
parts labelled 'a, b', 'c and 'd. [2
MARCH - 2020
10) The gaph given below shows the level of the ovarian hormones in a normally menstruating
wofnan during the follicular phase. [3]
Ovarian
Days 3 5 7 9 15 17 19 21 23 25 27 29/1
Menstruation Folicular phasc Lutoal phaSe Next cycke
(Proliferative phasc) (Secretory phase) begins
a) Name A and B
b) Reconstruct the graph showing the level of hormones in luteal phase.
) Name the hornone secreted by Corpus Luteum and mention its function.
11) "Allcopulations lead to fertilization and pregnancy". Do you agree with this statement ?
Justify your answer. (2)
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SAY- 2019
12) Find out the correct sequence : [1]
(a) Fertilisation- zygote - Blastula -Morula -cleavage- Implantation
(b) Fertilisation- zygote- cleavage -Morula -Implantation -Blastula
(c) Fertilisation- zygote- Morula -cleavage -Implantation -Blastula
(d) Fertilisation- zygote -cleavage- Morula -Blastula - Implantation
13) 'LH Surge' induces the rupture of Graafian follicle. [2]
(a) Which gland produces LH and in which day LH Surge happens?
(b) Write the role of LH in males.
MARCH -2019
14) The milk produced during the initial few days of lactation is called... [1]
15) Observe the diagram given below showing the sectional view of the female reproductive
system and name the parts labelled 'A', 'B/C &'D'. (2]
-C
A
(a) Identity Aand B.
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(b) Write the function of B. [2
MARCH- 2017
21) LH.and FSH aregonadotrophins. Distinguish their roles in males and females [2]
SAY- 2016
22) The process of fusion of a sperm with ovum is called 1
23) Match the following Aand B: [2
A B
Ovulation Sperm
Luteal Phase Oogenesis
Acrosome Blasto cyst
Inner cell mass LH
Progesterone
MARCH-2016
24) Match the followingA and B: [2]
A B
Corpus Luteum Embryo
Leydig cells Implantation
Blastocyst Prolactin
Inner cell mass Androgen
Progesterone
SAY- 2015
25) Complete the flowchart showing spermatogenesis by filling Aand Band answer the
questions.
A
Primary Secondary B Spermatozoa
Spermatocyte Spermatocyte
a What is the chromosome number of primary spermatocytes?
b. What is the significance of reduction division in spermatogenesis? [2
26) Choose the odd one from the following and write the common features of others.
a Estrogen b. Androgen
c Relaxin d. Progesterone [1]
MARCH- 2015
27)
a) In which part of the human reproductive system of the following events occur?
) Fertilisation
i) Implantation
b) Diagran of a human blastocyst is given below. ldentify A&B. (2]
-B
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SAY- 2014
29) Diagram of mammalian sperm is given. Label the marked parts.
A
-B
map
EDUCATIO
MARCH-2014
30) Observe the diagram, and answer the questions: (3]
a) ldentify A and B
b) What is the function of C?
c) In which of the marked part reduction division takes place?
What is the significance of it?
SAY -2013
a male or
31) "Though one ovum is produced from a primary oocyte it can result into
female chlld after fertilization. But in the case of spermatocytes though 4 sperms are
produced only two of them can result into a female child after fertilization." Justify. [1])
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