Sample Qstns

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PART 1

1. Explain various generations of computers with advantages and disadvantages of each


generation.
2. Compare TCP Vs UDP
3. Explain various network topologies
4. Explain various layers of the OSI Reference model
5. Explain Simplex, Half duplex and Full duplex modes of communication network.
6. What is network security? Explain the methods to achieve network security.
7. Explain Client-Server architecture and its types.
8. What is Network Topology? Explain various network topologies
9. Compare Virus, Worm, Trojan
10. Explain C-I-A Triad
11. Explain various components of DBMS
12. Explain various Cloud computing deployment types.
13. Explain the various types of Client-Server architecture
14. What is ELN? Write a note on how ELN helps in research activities.
15. Explain various graphical representations of data.
16. DNS, IP, NAT, Firewall, OS
17. Explain various cloud service models

PART 2
1. Facts and figures about Internet
2. What is the packet switching method in a communication network?
3. How it differs from circuit switching.
4. Compare Internet with WWW
5. Explain the different versions of the Web (1.0, 2.0, 3.0)
6. Draw the block diagram of information retrieval by search engines
7. Explain web crawling and indexing
8. Problem: Given a document, create an inverted index
9. The page rank algorithm of Google and problem
10. Google search commands
11. What is Search Engine Optimization. What steps can you take to get your website to
improve its web pagerank.
12. Name popular search engines other than Google
13. Name an AI-powered search engine and explain what it achieves.
14. What are embedded systems. What are the types of embedded systems.
15. Define IoT and its applications and implementation in Industrie 4.0
16. When can a dataset be classified as Big data.
17. 1 Petabyte = ? MB and similar conversions
18. Explain the 5 Vs of Big data
19. What are the defining characteristics of the industrial revolutions 1.0 to 4.0
20. Draw the Venn Diagram depicting the relationship between AI, ML and Deep learning
21. Biological concept underlying artificial neural networks ANN.
22. Algorithm for a typical ANN
23. What is the objective of the deep learning model ElemNet ?
24. How is AI re-inventing Computing hardware and software
PART 3

1. Which one among the following is the start codon?


CUG
AUG
AUU
UAG
2. BLOSUM62 is
amino acid substitution matrix
nucleic acid base matrix
nucleic acid substitution matrix
both a and c
3. Which of the following is not true about multiple sequence alignment?
can be used to derive phylogenic relationships
can be used for amino acid pattern identification
can be used structure determination
can be used for genome scale comparisons
4. Which of the following is not true about local alignment algorithm?
In trace back step, the path terminates when a 0 is encountered
First row and first column of matrix is set to 0 in initialization step
Score in a cell can be positive negative or 0
Gaps normally have a negative score
5. Which among the following is a protein domain database?
EMBL
TrEMBL
Interpro
Swissprot
6. Which of the following algorithms is/are based on dynamic programing?
Needleman & Wunch
Smith-Watermann
Both a & b
None of the above
7. Which among the following is a domain observed in transcription factors?
Tim Barrel
Rossman-Fold
Zinc Finger
EF Hand
8. Ramachandran Plot for proteins represents
Allowed torsion angles of amino acids in a peptide chain
Positions of secondary structures in a cartesian plane
Both a and b
None of the above
9. What is a protein domain database? Give an example
10. Differentiate between global and local alignments, what is their importance in context
of biological information?
11. What is PAM250 matrix?
12. Introduction of a gap in a sequence alignment has more penalty than introduction of a
mismatch. Explain the biological reason for this consideration.
Above mentioned are only sample questions

13. Use dynamic programing principles to find an optimal global alignment between the
following sequences (Please show the matrix building and trace back methods)
ACGATTCA
ACGCACA
14. Following is the Neutral zinc metallopeptidases, zinc-binding region signature
(PATTERN).
[GSTALIVN]-{PCHR}-{KND}-H-E-[LIVMFYW]-{DEHRKP}-H-{EKPC}-
[LIVMFYWGSPQ]
a) Identify the region in the following sequence and write down the sequence for the
signature from the sequence
MYYMPFFYDPYFWMIILGVAISGWASMNVNSTFNRYDQIQNHGNYTGKVAVRYILD
QAGLYEVEIREVAG
NLTDNYNPTNKVLSLSQSVYNSSSIAAVGVAAHEVGHALQDASDYAPMRLRSALVP
IVSLGSNLSMPLIL
LGLVLGMNQTLIKIGIWCFALVLVFQVVTLPVEFNASHRALRMLNNGAILDPQEMPI
ARKVLFAAALTYV
AAVLTSMLQLFRLILIFGRHNDDNN
b) Which residues are invariable in this region for maintaining biological function?
c) What does amino acids with the “{ }” signify

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