Periasamy Bharathi Sneha-14A (Selfwork-2)

MULTIPLE CHOICE QUESTIONS
AIDS
1. Which of the following is a symptom of AIDS?

a. Fever
b. Swollen lymph nodes
c. Tiredness
d. All of the above
2. The first ever instance of AIDS was reported in
a. USA
b. France
c. Russia
d. None of the above
3. HIV parasitizes ____
a. Y-helper cells
b. T-helper cells
c. K-helper cells
4. HIV can also spread through
a. Sharing water
b. Breathing in infected droplets
c. Sharing needles
d. Kissing
5. How many stages of HIV infection exist?
a. 3
b. 2
c. 1
d. No stages
6. HIV is thought to have originated from
a. Birds
b. Mosquitos
c. Chimpanzees
7. SIV is the abbreviation of:
a. Simian immunodeficiency virus
b. Siluridae immunodeficiency virus
c. Synodontidae immunodeficiency virus
8. In individuals with HIV, opportunistic infections are:
a. More frequent
b. Less frequent
c. Non-existent
9. HIV is a _____
a. Lentivirus
b. Capripoxvirus
c. Gallivirus
d. Papillomavirus
10. Simian immunodeficiency virus is known to affect
a. Non-human primates
b. Birds
c. Rabbits
11. A 27-year-old man has fever, macular rash, and
lymphadenopathy. He had unprotected sex with a male
partner 2 weeks before the onset of these symptoms and has
just learned that the partner is infected with HIV. The patient’s
rapid HIV test is negative. What is the best test to evaluate
this patient for HIV infection?
a. HIV enzyme-linked immunoabsorbent assay (ELISA)
b. PCR for HIV RNA
c. Western blot testing
d. Glycoprotein 120 using ELISA
e. PCR for HIV DNA
12. A 22-year-old male patient complains of fever and
shortness of breath. There is no pleuritic chest pain or rigors
and no sputum production. A chest x-ray shows diffuse
perihilar infiltrates. The patient worsens while on
azithromycin. A methenamine silver stain shows cystlike
structures.Which of the following is correct?
a. Definitive diagnosis can be made by serology.
b. The organism will grow after 48 hours.
c. History will likely provide important clues to the
diagnosis.
d. Cavitary disease is likely to develop.
e. The infection is unlikely to recur.
13. A 47-year-old HIV-positive man is brought to the
emergency room because of weakness. The patient has HIV
nephropathy and adrenal insufficiency. He takes
trimethoprim-sulfamethoxazole for PCP prophylaxis and is
on triple-agent antiretroviral treatment. He was recently
started on spironolactone for ascites due to alcoholic liver
disease. Physical examination reveals normal vital signs, but
his muscles are diffusely weak. Frequent extrasystoles are
noted. He has mild ascites and 1 + peripheral edema.
Laboratory studies show a serum Creatinine of 2.5 with a
potassium value of 7.3 mEq/L. An EKG shows peaking of the T
waves and QRS duration of 0.14. What is the most important
immediate treatment?
a. Sodium polystyrene sulfonate (Kayexalate)
b. Acute hemodialysis
c. IV normal saline
d. IV calcium gluconate
e. IV furosemide 80 mg stat
14. A 29-year-old man with HIV, on a highly active

antiretroviral therapy (HAART) regimen including the
protease inhibitor indinavir, presents with severe edema and
a serum creatinine of 2.0 mg/dL. He has had bone pain for 5
years and takes large amounts of acetaminophen with
codeine, aspirin, and Ibuprofen. He is on prophylactic
trimethoprim-sulfamethoxazole. Blood Pressure is 170/110;
urinalysis shows 4+ protein, 5 to 10 RBC, 0 WBC; 24-hour urine
protein is 6.2 g. The serum albumin is 1.9 g/L (normal above 3.7).
Which of the following is the most likely cause of his renal
disease?
a. Indinavir toxicity
b. Analgesic nephropathy
c. Trimethoprim-sulfamethoxazole–induced interstitial
nephritis
d. Focal glomerulosclerosis
e. Renal artery stenosis
15. A 34-year-old homosexual man with a history of HIV
presents to the clinic complaining of wheezing and multiple
violaceous plaques and nodules on his trunk and extremities.
Physical examination of the oral mucosa reveals similar
findings on his palate, gingiva, and tongue. Chest x-ray is also
significant for pulmonary infiltrates. What is the most likely
pathogenesis of this process?
a. Proliferation of neoplastic T cells
b. Infection with human herpesvirus 6
c. Infection with Mycobacterium avium due to decreasing
CD4 count
d. Angioproliferative disease caused by infection with
human herpesvirus 8
e. Disseminated herpes simplex infection.
16. AIDS (Acquired Immuno Deficiency Syndrome) Day is
a. May 1
b. December 1
c. December 20
d. June 1
17. AIDS was first reported in

a. Russia
b. France
c. Germany
d. USA
18. AIDS can be transmitted by
a. Blood transfusion
b. Courtship
c. Handshake
d. All of the above
19.AIDS is caused by
a. Blood cancer
b. Human T-cell leukaemia virus
c. Bacterium
d. TMV
20.AZT (3’-azido 2’. 3’-dideoxy thymine) is used in the
treatment of
a. Malaria
b. AIDS
c. Kala-azar
21.HIV virus has a protein coat and a genetic material which is
a. Double stranded DNA
b. Single stranded RNA
c. Double stranded RNA
d. Single stranded DNA
22.Which of the following could be called immune disorder?
a. AIDS and cholera
b. SCID and AIDS
c. AIDS and cholera
d. Hepatitis and leukaemia
23.The confirmatory test used to diagnose AIDS is
a. ELISA
b. Western blot
c. ESR
d. PCR
24.AIDS testing on normal individuals is done by
a. Separation by virus
b. Reduction in immunity of the individuals
c. Identification of antibodies
d. Identification of antigen-toxin
25.AIDS is
a. Endemic
b. Epidemic
c. Pandemic
d. Sporadic
26.HIV belongs to which of the following families of virus?
a. Reovirus
b. Lentivirus
c. Togavirus
d. Adenovirus
27.Development of vaccine is difficult for AIDS because env
gene
a. Undergoes mutation at rapid rate
b. Undergoes reverse transcription
c. Integrates into large number of host genes
d. Integrates its genome into that of helper T cells
28.The causative agent for AIDS was first of all identified in
1984 and was named as
a. HIV-1
b. HIV-2
c. LAV
d. HTLV III
29.AIDS spread due to
a. Homosexuality
b. Immoral way of life
c. Infected needles and syringes
d. All of the above
30.The virus that causes acquired immune deficiency
syndrome (AIDS) parasitizes
a. B cells
b. Cytoxic Tcells
c. Helper T cells
d. The membrane of lymph nodes

Periasamy Bharathi Sneha-14A (Selfwork-2)

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Periasamy Bharathi Sneha-14A (Selfwork-2)

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MULTIPLE CHOICE QUESTIONS

1. Which of the following is a symptom of AIDS?

14. A 29-year-old man with HIV, on a highly active

17. AIDS was first reported in

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