Dental Notes 1
Dental Notes 1
Dental Notes 1
PATHWAY
1. Olfactory chemoreceptors (epithelium)
2. Glomerulus (olfactory bulb)
3. Mitral cells (olfactory bulb)
4. Lateral olfactory tract
5. Olfactory cortex
PHYSIOLOGY
• Odorant molecules dissolve in mucus that covers the epithelium
• Binds to odorant receptors on odorant receptor cells on the cilia of chemoreceptor cells, in
nasal cavity
• 1 odorant chemical = recognised by multiple olfactory receptors
• 1 receptor = recognise multiple odorants
• Detection of particular odorant = encoded by firing of distinct combination of sensory cells
• Golf protein es second messengers
• Increased conductance of Na+z & Ca2+—> depolarisation
• Olfactory information = patterns of neutron activity
• Strength of odorant = frequency of neural discharge