CELL CYCLE AND CELL DIVISIONS
1. The replication of nuclear DNA occurs in
(A) G1 phase (B) G2 phase
(B) S phase (D) M phase
2. Colchicum obtained from Colchicum autumnale plant, affects
which stage of cell division?
(A) Metaphase (B) Telophase
(C) Prophase (D) Anaphase
3. “G0” state of cells in eukaryotic cell cycle denotes
(A) Check point before entering the next phase
(B) Pausing in the middle of a cycle to cope with a
temporary delay
(C) Death of a cell
(D) Exit of cells from cell cycle
4. Mitosis is the process by which eukaryotic cells
(A) Expose the genes for protein synthesis
(B) Become specialized in structure and function
(C) Multiply
(D) Grow
5. Which will be the best stage to count the number of
chromosomes during mitosis?
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(A) Prophase (B) Metaphase
(C) Anaphase (D) Telophase
5. The significance of meiosis lies in
(A) Reduction of the diploid number of chromosomes to
haploid
(B) Maintaining constancy in the number of diploid
chromosomes during sexual reproduction
(C) Production of genetic variability in the population of a
species
(D) All the above
6. Which one of the following pairs is correctly matched
(A) Anaphase I Homologous chromosomes are separated
Pairing of maternal and paternal homologous
(B) Metaphase I chromosomes takes place
A nuclear envelope encloses each haploid set
(C) Interphase of chromo somes
Non-homologous chromosomes are
(D) Prophase I separated
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7. Match List I and List II and select the correct answer using
the code given below in the lists :
List I(Phase of
meiosis) List II(Event that occurs)
1. Prophase I Crossing over occurs
2. Metaphase I Sister chromatids migrate to opposite poles
3. Anaphase I Homologous line up at equator in pairs
Code:
(A) 1, 2 and 3 are correct
(B) 1 and 2 are correct, 3 is false
(C) 1 is correct, 2 and 3 are false
(D) 1 and 3 are correct, 2 is false
8. DNA replication occurs during
(A) Prophase (B) Metaphase
(C) Anaphase (D) Interphase
(E) Leptotene
9. Chiasmata formation occurs during
(A) Diplotene (B) Leptotene
(C) Pachytene (D) Diakinesis
10. The number of chromatids in a chromosome at anaphase is
(A) 2 in mitosis and 1 in meiosis
(B) 1 in mitosis and 2 in meiosis
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(C) 2 each in mitosis and meiosis
(D) 2 in mitosis and 4 in meiosis
11. In mitosis the duplication of chromosomes occurs during
(A) Early prophase (B) Late prophase
(C) Interphase (D) Late telophase
12. The process of mitosis is divided into 4 phases. Identify the
correct order in which these phases appear in mitosis
(A) Anaphase, metaphase, telophase and prophase
(B) Telophase, anaphase, metaphase and prophase
(C) Metaphase, prophase, anaphase and telophase
(D) Prophase, metaphase, anaphase and telophase
13. The homologous chromosomes follow the process of
synapsis in the stage or Pairing of homologous
chromosome takes place in
(A) Leptotene (B) Zygotene
(C) Diplotene (D) Pachytene
14. The process of mitosis can be studied in
(A) Onion root tip (B) Garlic root tip
(C) Tendril tip (D) All of the above
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15. Prophase of reduction division is divided into number of
stages. The correct chronological sequence is
(A) Leptotene — pachytene — zygotene — diplotene —
diakinesis
(B) Leptotene — diplotene — pachytene — zygotene —
diakinesis
(C) Leptotene — zygotene — diplotene — pachytene —
diakinesis
(D) Leptotene — zygotene — pachytene — diplotene —
diakinesis
16. Regarding the sequence of cell cycle, which one is corect
(A) G1, G2, S and M (B) S, G1, G2, and M
(C) G1, S, G2 and M (D) G2, S, G1, and M
17. How many mitotic divisions are needed for a single cell to
make 128 cells
(A) 7 (B) 14
(C) 28 (D) 32
18. What will be the number of mitotic divisions to make 128 cells
from a single cell?
(A) 7 (B) 4 (C) 28 (D) 32
19. During mitosis chromosomes go to their poles in a stage
called
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(A) Prophase (B) Metaphase
(C) Anaphase (D) Telophase
20. When, during the meiotic division, do the centromeres
divide
(A) Diplotene (B) Metaphase–I
(C) Pachytene (D) Anaphase–II
21. DNA replication takes place in
(A) G1 phase (B) G2 phase
(C) S phase (D) Mitotic phase
22. The number of chromosomes after I phase of meiotic
division in reduction division
(A) Remain unchanged (B) Become doubled
(B) Become halved (D) None of the above
23. Meiosis can be observed in
(A) Root tips (B) Cambium
(B) Anther (PMC) (D) Pollen grains
24. Phragmoplast is precursor of
(A) Cell plate (B) Chloroplast
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(C) Chromoplast (D) Colourless plastid
25. Cell plate is referred as
(A) Germplast (B) Idioblast
(C) Phragmoplast (D) Middle lamella
26. The nuclear membrane disappears in
(A) Metaphase (B) Early prophase
(C) Late prophase (D) Anaphase
27. Chromonemata start associating into bivalent chromosomes
during
(A) Zygotene (B) Leptotene
(C) Pachytene (D) Diplotene
28. The study of chromosomes at meiotic diplotene shows that
(A) The intimately paired chromosomes repel each other
and begin to separate
(B) The pairing of homologous chromosomes which had
initiated in the earlier stage is completed
(C) The homologous chromosomes remain united by
chiasmata
(D) None of the above
29. Exchange of chromosome segments between maternal and
paternal chromatids during meiosis is called
(A) Linkage (B) Dominance
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(C) Crossing over (D) DNA multiplication
30. Spindle fibres are made up of
(A) Proteins (B) Cellulose
(C) Lipids (D) Pectin
31. Which is not true for anaphase
(A) Golgi body and ER are reformed
(B) Chromosomes move to opposite poles
(C) Spindle poles move farther apart
(D) Centromeres split and chromatids separate
32. In which phase proteins for spindle fibre formation are
synthesized
(A) G1 phase (B) G2 phase
(C) S-phase (D) Anaphase
33. In eukaryotic cell cycle, cell fusion experiments show that
(A) When an S-phase cell is fused with a G1-phase cell, G1-
phase cell is stimulated to synthesize DNA.
(B) When an S-phase cell is fused with a G1-phase cell.
(C) When a G1-phase cell is fused with a G1-phase cell,
DNA synthesis is induced in both G1 and G2 phase cells.
(D) When a G1-phase cell is fused with an M-phase.
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34. DNA and histone proteins are synthesized during the
following phase of cell cycle
(A) S phase (B) G2 phase
(C) G1 phase (D) None of these
35. At which phase of meiosis, the two cells, each with
separated sister chromatids move towards opposite poles
(A) Metaphase I (B) Metaphase II
(C) Anaphase I (D) Anaphase II
36. During which stage of meiosis, the four group of
chromosomes arrange themselves into haploid nuclei and the
spindle fibres degenerate?
(A) Prophase II (B) Metaphase II
(B) Anaphase II (D) Telophase II
37. In the somatic cell cycle
(A) A short interphase is followed by a long mitotic phase.
(B) G2 phase follows mitotic phase.
(C) In G1 phase DNA content is double the amount of DNA
present in the original cell.
(D) DNA replication takes place in S-phase.
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38. At which stage of meiosis the enzyme recombinase is
required?
(A) Zygontene
(B) Diplotene
(C) Diakinesis
(D) Pachytene
39.During the meiotic division the
(A) Homologous chromosomes are separated
(B) The linkage is disturbed
(C) The homologous chromosomes do not segregate
(D) All of the above
40. During the G phase of cell division
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(A) RNA and proteins are synthesized
(B) DNA and proteins are synthesized
(C) Cell prepares for M-phase
(D) Cell undergoes duplication
41. Meiosis is found at
(A) Shoot apex (B) Reproductive part
(C) Leaves bud (D) Vegetative parts
42. Homologous pairing in prophase I of meiosis I is called
(A) Synapsis (B) Linkage
(C) Crossing over (D) Syndesis
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43. In meiosis the daughter cells are not similar to that of
parent because of
(A) Crossing over (B) Synapsis
(C) Both (A) and (B) (D) None of these
44. Diploid living organism develops from zygote by repeated
cell divisions is called
(A) Meiosis (B) Amitosis
(C) Mitosis (D) Segmentation
ANSWERS
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
C A D C B D A C D A B C D B D
16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
D C A B C D C C C A C C A C C
31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
A A B B A D C D A A A B A A C
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SOLUTIONS
2. Colchicine obtained from Colchicum autumnale plant, acts
as a poison for mitosis as it inhibits the formation of mitotic
spindle fibers in metaphase. Hence it stops cell division at
metaphase of mitosis.
3. When cells are not to divide after G phase and start
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undergoing differentiation into specific types of cells such
cells are said to be in G0 phase/G0 state.
5. The chromosomes move to spindle equator and align along
the metaphase plate through spindle fibres to both poles. At
this stage, the chromosomes can be easily observed under
the microscope.
9. Because interphase is the growth phase of cell.
12. In the S-phase (synthesis phase) of interphase DNA is
replicated and then the DNA content of nucleus become
doubled. It is also known as duplication of chromosome.
14. In zygotene of prophase of meiosis, chromosomes pairing
occurs for crossing over.
18. A single mitotic division produces two cells from a single
cell and the second division of these two cells will produce
4 cells and so on. Therefore (2)n = Number of cells after n
divisions. Thus, 7 generations of mitosis yields 128 cells
from a single cell.
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21. Anaphase-II is simple mitotic division of meiosis; in this
process centromeres divide and form two separate
chromosomes.
23. Because first phase of meiosis includes reduction division
while second phase exhibits mitotic divisions.
24. As a result of it pollen grains formed.
28. Pairing between the homologous chromosomes takes place
in zygotene stage of prophase-I
29. This occurs for the exchange of genetic material during
crossing over.
36. During Telophase II, the four group of chromosomes
arrange themselves into haploid nuclei and the
chromosomes elongate to form chromatin. A nucleolus is
also produced followed by the formation of nucleoplasm
and a nuclear envelope. The spindle fibres usually
degenerate during telophase II.
38. During pachytene crossing over occurs which is an
enzyme-mediated process that requires the enzyme
recombinase.
39. Due to attachment of spindle fibres at the centromeres
(kinetochore) of chromosomes, the chromosomes are
arranged in the centre or at equator or equatorial plate or
metaphase due to their active movements.
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