Scribd Logo
Upload

Welcome to Scribd!

  • 31 views

    BIO270 Tuto 5

    Uploaded by

    Mirza Karmila
    1. The document differentiates between innate and acquired immunity in 3 sentences: Innate immunity is the first line of defense and is effective from birth with no memory and an immediate but non-specific response. Acquired immunity is the second line of defense and develops after exposure, has memory, and a delayed but specific response. 2. T-cells and B-cells are differentiated in 3 sentences: T-cells have TCRs and are long-lived, developing in the bone marrow before migrating to the thymus and secreting cytokines and cellular effectors. B-cells have BCRs, are short-lived, develop in the bone marrow, and secrete Ig and cytokines as well as

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    BIO270 Tuto 5

    Uploaded by

    Mirza Karmila
    31 views3 pages
    1. The document differentiates between innate and acquired immunity in 3 sentences: Innate immunity is the first line of defense and is effective from birth with no memory and an immediate but non-specific response. Acquired immunity is the second line of defense and develops after exposure, has memory, and a delayed but specific response. 2. T-cells and B-cells are differentiated in 3 sentences: T-cells have TCRs and are long-lived, developing in the bone marrow before migrating to the thymus and secreting cytokines and cellular effectors. B-cells have BCRs, are short-lived, develop in the bone marrow, and secrete Ig and cytokines as well as

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    1. The document differentiates between innate and acquired immunity in 3 sentences: Innate immunity is the first line of defense and is effective from birth with no memory and an immediate but non-specific response. Acquired immunity is the second line of defense and develops after exposure, has memory, and a delayed but specific response. 2. T-cells and B-cells are differentiated in 3 sentences: T-cells have TCRs and are long-lived, developing in the bone marrow before migrating to the thymus and secreting cytokines and cellular effectors. B-cells have BCRs, are short-lived, develop in the bone marrow, and secrete Ig and cytokines as well as

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    31 views3 pages

    BIO270 Tuto 5

    Uploaded by

    Mirza Karmila
    1. The document differentiates between innate and acquired immunity in 3 sentences: Innate immunity is the first line of defense and is effective from birth with no memory and an immediate but non-specific response. Acquired immunity is the second line of defense and develops after exposure, has memory, and a delayed but specific response. 2. T-cells and B-cells are differentiated in 3 sentences: T-cells have TCRs and are long-lived, developing in the bone marrow before migrating to the thymus and secreting cytokines and cellular effectors. B-cells have BCRs, are short-lived, develop in the bone marrow, and secrete Ig and cytokines as well as

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    1.

    Differentiate between innate and acquired immunity (5m)


    Innate immunity Acquired immunity
    1st line of defense 2nd line of defense
    Effective from the time of birth Develops after esxposure to inducing agents.
    No memory Memory present
    Immediate response Not immediate response
    Non-specific response to pathogens Specific response to pathogens

    2. Differentiate between T-cell and B-cell receptors (5m)


    *klw dpt lukis,lukis yah.
    *sbb lukisan ada markah
    *bole ikut point dkt miss punya simple notes
    T-cells B-cells
    TCRs BCRs
    Long-lived Short lived
    Developed in red bone marrow before Developed in red bone marrow
    migrating to thymus
    Secretes cytokinesis Secrets ig and cytokinesis
    Cellular and humoral effectors Humoral effector only
    3. Differentiate between humoral and cell mediated acquired immunity (5m)
    *buat mcm apa miss ckp dkt discussion for tutorial.
    *tambah table utk classes dia
    Humural Immunity Cell Mediated Immunity
    mediated by antibody Mediated by cytotoxic lymphocyets
    Main cells are B-cells Main cells are T-cells
    The onset is rapid The onset is delayed
    Protect againts extracellular pathogens Protect againts intracellular pathogens
    The end of the result of activation is the
    The end of the result of the activation is the
    differentiation of plasma B-cells, secreting
    secretion of cytokines
    antibodies

    4. Explain and give examples of 5 classes of antibodies (10m)


    *klw bole buat jadual spaya senang.

    I. igG (monomer)
    -secreted by plasma cells in the blood
    -able to cross placenta to fetus
    -promote opsonization, neurtralization and agglutination of antigents and less effective in
    complement activation than igM

    II. igA (dimer)


    -found in mucus, saliva tears and breast milk.
    -provides localized defense of mucous membranes by agglutination and neutralization of
    antigens
    -protects againts pathogens
    III. IgM (pentamer)
    -May be attached to the surface of B-cell in blood.
    -promotes neutralization and agglutination of antigents which is very effective in complement
    activation.

    IV. igE (monomer)


    -triggers release from mast cells and basophils of histamnie and other chemicals that cause
    allergic reactions.

    V. igD (monomer)
    -parts of the B-cell receptor
    -act as antigen receptor in antigen-stimulated proliferation and differentiation of B cells.

    You might also like