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Patient Care & Health Information Diseases & Conditions

Moles
Moles
SECTIONS
Moles are usually harmless. They may
contain
Print hairs or become raised or wrinkled.
Talk to your doctor about any change in the
Overview
color or size of a mole or if itching, pain,
bleeding or inflammation develops.
Moles are a common type of
skin growth. They often
appear as small, dark brown
spots and are caused by
clusters of pigmented cells.
Moles generally appear during
childhood and adolescence. Moles
Most people have 10 to 40
moles, some of which may
change in appearance or fade
away over time.

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Most moles are harmless. Rarely, they become


cancerous. Monitoring moles and other
pigmented patches is an important step in
detecting skin cancer, especially malignant
melanoma.

The medical term for moles is nevi.

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Symptoms
The typical mole is a brown spot. But moles
come in different colors, shapes and sizes:

Color and texture. Moles can be brown,


tan, black, red, blue or pink. They can be
smooth, wrinkled, flat or raised. They may
have hair growing from them.

Shape. Most moles are oval or round.

Size. Moles are usually less than 1/4 inch


(about 6 millimeters) in diameter — the size
of a pencil eraser. Rarely, moles present at
birth (congenital nevi) can be much bigger,
covering wide areas of the face, torso or a
limb.

Moles can develop anywhere on your body,


including your scalp, armpits, under your nails,
and between your fingers and toes. Most people
have 10 to 40 moles. Many of these develop by
age 50. Moles may change in appearance or
fade away over time. Hormonal changes of
adolescence and pregnancy may cause moles to
become darker and larger.

Unusual moles that may indicate


melanoma
This ABCDE guide can help you determine if a
mole or a spot may indicate melanoma or other
skin cancers:

A is for asymmetrical shape. One half is


unlike the other half.

B is for border. Look for moles with


irregular, notched or scalloped borders.

C is for color. Look for growths that have


changed color, have many colors or have
uneven color.

D is for diameter. Look for new growth in a


mole larger than 1/4 inch (about 6
millimeters).

E is for evolving. Watch for moles that


change in size, shape, color or height,
especially if part or all of a mole turns black.
Moles may also evolve to develop new
signs and symptoms, such as itchiness or
bleeding.

Cancerous (malignant) moles vary greatly in


appearance. Some may show all of the features
listed above. Others may have only one or two.

When to see a doctor


Make an appointment with your doctor if a mole
looks unusual, grows or changes.

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Clinic

Causes
Moles are caused when cells
in the skin (melanocytes) grow
in clusters or clumps.
Melanocytes are distributed
throughout your skin and
produce melanin, the natural
pigment that gives your skin its
color. Skin layers
and melanin
Complications
Melanoma is the main complication of moles.
Some people have a higher than average risk of
their moles becoming cancerous and developing
into melanoma. Factors that increase your risk of
melanoma include:

Being born with large moles. These types


of moles are called congenital nevi. On an
infant, such moles are classified as large if
they're more than 2 inches (5 centimeters)
in diameter. Even a large mole seldom
becomes cancerous and almost never
before the child reaches puberty.

Having unusual moles. Moles that are


bigger than a common mole and irregular in
shape are known as atypical (dysplastic)
nevi. They tend to be hereditary. And they
often have dark brown centers and lighter,
uneven borders.

Having many moles. Having more than 50


ordinary moles indicates an increased risk
of melanoma. Two studies add to the
evidence that the number of your moles
predict cancer risk. One showed that people
under 50 years old who have 20 or more
moles on their arms are at increased risk of
melanoma. Another showed a relationship
between the number of women's moles and
breast cancer risk.

Having a personal or family history of


melanoma. If you've had melanoma before,
you are at increased risk of a mole
becoming cancerous. In addition, some
types of atypical moles lead to a genetic
form of melanoma.

Prevention
The following measures can help limit the
development of moles and the main complication
of moles — melanoma.

Watch for changes


Become familiar with the location and pattern of
your moles. Regularly examine your skin to look
for changes that may signal melanoma. Do self-
exams once a month, especially if you have a
family history of melanoma. With the help of
mirrors, do a head-to-toe check, including your
scalp, palms and fingernails, armpits, chest, legs,
and your feet, including the soles and the spaces
between the toes. Also check your genital area
and between your buttocks.

Talk with your doctor about your risk factors for


melanoma and whether you need a professional
skin exam on a routine basis.

Protect your skin


Take measures to protect your skin from
ultraviolet (UV) radiation, such as from the sun or
tanning beds. UV radiation has been linked to
increased melanoma risk. And children who
haven't been protected from sun exposure tend
to develop more moles.

Avoid peak sun times. For many people in


North America, the sun's rays are strongest
between 10 a.m. and 4 p.m. Schedule
outdoor activities for other times of the day,
even on cloudy days or in winter.

Use sunscreen year-round. Apply


sunscreen about 30 minutes before going
outdoors, even on cloudy days. Use a
broad-spectrum sunscreen with an SPF of
at least 15. Apply it generously and reapply
every two hours — or more often if you're
swimming or sweating. The American
Academy of Dermatology recommends
using a broad-spectrum, water-resistant
sunscreen with an SPF of at least 30.

Cover up. Sunglasses, broad-brimmed


hats, long sleeves and other protective
clothing can help you avoid damaging UV
rays. You might also want to consider
clothing that's made with fabric specially
treated to block UV radiation.

Avoid tanning lamps and beds. Tanning


lamps and beds emit UV rays and can
increase your risk of skin cancer.

By Mayo Clinic Staff

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Clinic

Diagnosis & treatment

Nov. 19, 2019

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