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Ganirelix Drug Study

Ganirelix acetate is a GnRH antagonist used to inhibit premature luteinizing hormone surges in patients undergoing controlled ovarian hyperstimulation. It works by rapidly and profoundly suppressing endogenous gonadotropins via modulation of the hypothalamic-pituitary-gonadal axis. Common side effects include redness or pain at the injection site, headache, mild nausea, and stomach or pelvic pain. Nurses are responsible for assessing patients for drug effects and allergic reactions, and monitoring lab tests for those undergoing treatment.

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128 views2 pages

Ganirelix Drug Study

Ganirelix acetate is a GnRH antagonist used to inhibit premature luteinizing hormone surges in patients undergoing controlled ovarian hyperstimulation. It works by rapidly and profoundly suppressing endogenous gonadotropins via modulation of the hypothalamic-pituitary-gonadal axis. Common side effects include redness or pain at the injection site, headache, mild nausea, and stomach or pelvic pain. Nurses are responsible for assessing patients for drug effects and allergic reactions, and monitoring lab tests for those undergoing treatment.

Uploaded by

happymee927
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Drug Mechanism of Action Indications Side Effects Nursing Responsibility

Generic Name: ganirelix acetate Ganirelix modulates the Inhibition of premature luteinizing redness or pain at the injection site Assessment & Drug Effects
Brand Name: Ganirelix Acetate hypothalamic-pituitary-gonadal axis hormone surge in patients
Injection by causing a rapid, profound, undergoing controlled ovarian reactions (pain, redness, or Exercise caution with patients with
Classification: GnRH Antagonist reversible suppression of hyperstimulation irritation), headache, mild nausea, hypersensitivity to GnRH or with
endogenous gonadotropins. During known allergic disorders (e.g.,
stomach pain, tiredness, pelvic pain
Dosage/Route/Frequency: controlled ovarian stimulation, it asthma, hay fever). These patients
250 mcg subcutaneously initiated suppresses luteinizing hormone (similar to menstrual cramps), or should be carefully monitored after
on day 2 or 3 of the menstrual cycle (LH) and follicle-stimulating vaginal bleeding. the first injection for S&S of an
and continued daily until day of hormone (FSH) secretion from the
anaphylactic reaction.
human chorionic gonadotropin pituitary gland
Lab tests: Monitor baseline and
(hCG) administration
periodic CBC with differential, and
References: periodic total bilirubin.
http://www.robholland.com
/Nursing/Drug_Guide/data/ Contraindication/s Adverse Reaction/s Patient & Family Education
monographframes/G005.html contraindicated in patients with allergic reactions like skin rash,
known hypersensitivity to degarelix itching or hives, swelling of the Report menstrual disorders (e.g.,
or to any of the product face, lips, or tongue. breathing spotting, frank vaginal bleeding) to
components. problems. nausea and vomiting physician.
women who are or may become along with severe stomach pain. Notify physician immediately if you
pregnant pelvic pain or bloating. think you are pregnant.
Do not breast feed while taking this
drug.

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