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    Pharmaceutical Biochemistry T

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    Alah Bacot.
    This document outlines the course details for Pharmaceutical Biochemistry, including the objectives, outcomes, modules, reference books, and sample question paper. The course aims to explore applied biochemistry and prepare students for industries like pharmaceutical R&D and clinical trials. It covers 4 modules: 1) Introduction to pharmacology and biochemistry, 2) Pharmacokinetics, 3) Pharmacodynamics, and 4) Adverse drug effects. The modules will discuss topics like drug transport, metabolism, action, and side effects. Students will understand drug development and evaluation and their biochemical basis. Assessment includes long and short answer questions testing the concepts learned throughout the course.

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    Pharmaceutical Biochemistry T

    Uploaded by

    Alah Bacot.
    103 views4 pages
    This document outlines the course details for Pharmaceutical Biochemistry, including the objectives, outcomes, modules, reference books, and sample question paper. The course aims to explore applied biochemistry and prepare students for industries like pharmaceutical R&D and clinical trials. It covers 4 modules: 1) Introduction to pharmacology and biochemistry, 2) Pharmacokinetics, 3) Pharmacodynamics, and 4) Adverse drug effects. The modules will discuss topics like drug transport, metabolism, action, and side effects. Students will understand drug development and evaluation and their biochemical basis. Assessment includes long and short answer questions testing the concepts learned throughout the course.

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    Pharmaceutical_Biochemistry_T

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    This document outlines the course details for Pharmaceutical Biochemistry, including the objectives, outcomes, modules, reference books, and sample question paper. The course aims to explore applied biochemistry and prepare students for industries like pharmaceutical R&D and clinical trials. It covers 4 modules: 1) Introduction to pharmacology and biochemistry, 2) Pharmacokinetics, 3) Pharmacodynamics, and 4) Adverse drug effects. The modules will discuss topics like drug transport, metabolism, action, and side effects. Students will understand drug development and evaluation and their biochemical basis. Assessment includes long and short answer questions testing the concepts learned throughout the course.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    103 views4 pages

    Pharmaceutical Biochemistry T

    Uploaded by

    Alah Bacot.
    This document outlines the course details for Pharmaceutical Biochemistry, including the objectives, outcomes, modules, reference books, and sample question paper. The course aims to explore applied biochemistry and prepare students for industries like pharmaceutical R&D and clinical trials. It covers 4 modules: 1) Introduction to pharmacology and biochemistry, 2) Pharmacokinetics, 3) Pharmacodynamics, and 4) Adverse drug effects. The modules will discuss topics like drug transport, metabolism, action, and side effects. Students will understand drug development and evaluation and their biochemical basis. Assessment includes long and short answer questions testing the concepts learned throughout the course.

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    © All Rights Reserved
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    of 4

    CBCS – 2020 Sem VI - Pharmaceutical Biochemistry

    SEMESTER – VI
    PHARMACEUTICAL BIOCHEMISTRY
    THEORY

    Programme: B.Sc. Max. Hours: 45


    Course Code: U20/BIC/DSE/602 Hours per week: 3
    Course Type: DSE – 1 Max. Marks: 100
    No. of credits: 3

    Course Objectives:

    Our Graduate students will be able to explore the dimensions of applied Biochemistry.
    They will be ready for Industries like pharmaceutical R & D, Clinical Trials.

    Course Outcomes:

    CO1: Understand the principles of pharmacology and pharmaceutical biochemistry.


    CO2: Analyze biochemical approach to drugs and drug mechanism.
    CO3: Interpret and summarize benefits of drug components and adverse drug effects.
    CO4: Create conceptual knowledge dimensions for their benefits.

    Department of Biochemistry, St. Francis College for Women, Hyderabad-16.


    CBCS – 2020 Sem VI - Pharmaceutical Biochemistry

    MODULE I: INTRODUCTION TO PHARMACOLOGY (10 Hrs)

    Introduction to Pharmacology and pharmaceutical biochemistry. Blood-Buffer System.


    Biological Membranes and transport systems. History of Drugs,Sources and Classification of
    drugs

    MODULE II: PHARMACOKINETICS (12 Hrs)


    Absorption, Bioavailability& Distribution of drugs .Routes of drug administration.
    Biotransformation – Metabolism of Drugs. Inhibition of Drug Metabolism. Overview of drugs as
    inhibitors to enzymes ACE ,leukotrienes, Lipoxygenase, Cycloxygenase, DNA Polymerase
    Inhibitors, HIV - Protease /Reverse Transcriptase, Integrase. Excretion & Kinetics of
    Elimination.

    MODULE III: PHARMACODYNAMICS (12 Hrs)

    Principles & Mechanism of Drug action though Chemicals, Enzymes (Stimulation and
    Inhibition), Receptors. (Drug Receptor Interaction) Drug-dose response, combined effect of
    Drugs, Drug Dosage. Factors modifying Drug action.
    Introduction to Chemotherapy, Miscellaneous drugs & essential drugs – their therapeutic uses &
    biochemical/ metabolic relevance. Role of vaccines and sera in pharmaceutics.

    MODULE IV: ADVERSE DRUG EFFECTS (11 Hrs)


    Adverse responses – Side effects, Secondary effects, Toxic effects, Intolerance, Idiosyncrasy,
    and Allergy of drugs. (Mechanisms and Types of allergic reactions). Photosensitivity due to
    drugs. Drug Dependence – Drug abuse and addiction. Drug withdrawal reactions, Teratogenicity,
    Carcinogenicity, Mutagenicity. Drug induced Diseases.
    Overview of the list of banned drugs in India and WHO recommendations.

    Department of Biochemistry, St. Francis College for Women, Hyderabad-16.


    CBCS – 2020 Sem VI - Pharmaceutical Biochemistry

    Reference Books:

    1. The Pharmacology volume I and II –Goodman and Gillman.


    2. Essentials of Pharmaceutical biochemistry including practical exercises (EDN 2) by
    HarbansLal, International Edition, 2019.
    3. Biochemistry for the pharmaceutical sciences by Charles P. Woodbury, 2011.
    4. Pharmacology and Pharmatherapeutics – R.S.Satoskar,S.D.Bhandhakarand.
    5. Lippincotts illustrated review Pharmacology.
    6. Essentials of Medical Pharmacology by K D Tripathi.
    7. Clinical Chemistry by Bishop, Duben- Engelkirk&Fody.

    Department of Biochemistry, St. Francis College for Women, Hyderabad-16.


    CBCS – 2020 Sem VI - Pharmaceutical Biochemistry

    PHARMACEUTICAL BIOCHEMISTRY

    MODEL QUESTION PAPER

    THEORY

    Course Code: U20/BIC/DSE/602 Max. Marks: 60


    Credits: 3 Time: 2 Hrs

    SECTION – A

    I. Answer the following 4 x 10 = 40 M

    1 Discuss biological membrane transport systems.


    (OR)
    2. Write a note on sources and classification of Drugs.

    3. Discuss routes of drug administration with examples.


    (OR)
    4. Explain role of drugs as enzyme inhibitors with examples.

    5. Discuss factors modifying drug action.


    (OR)
    6. Write a note on essential drugs and their metabolic relevance.

    7. Explain adverse drug responses in brief.


    (OR)
    8. Write a note on drug abuse and addiction.

    SECTION – B

    II. Answer any FOUR 4 x 5 = 20 M

    9. Blood buffers
    10. Drug excretion
    11. Drug dosage
    12. Chemotherapy
    13. Drug allergy
    14. Vaccine &Sera

    Department of Biochemistry, St. Francis College for Women, Hyderabad-16.

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