Material Safety Data Sheet

Section 1 – Identification
1.1 Product Name MediaBox Buffered Listeria Enrichment Broth
1.2 Catalog Number 68-C00150 (5L), 68-C00151(10L), 68-C00152 (20L)

1.3 Manufacturer Microbiology International

Address 5350 Partners Court
Frederick, MD 21703
1.4 Phone 301-662-6835
1.5 Fax 301-662-8096
1.6 Emergency Phone 1-800-396-4276
1.7 Recommended Use For the selective enrichment of Listeria spp.
Section 2 – Hazard(s) Identification
2.1 Classification System:
Classification (29 CFR 1910.1200)
- Toxic to reproduction, Cat. 1B, H360
Classification (REGULATION (EC) No 1272/2008) [CLP/GHS]
- Repr. 1B, H360
Classification (WHMIS 2015 HPR)
- Toxic to reproduction, Cat. 1B, H360
Additional information: For full text of Hazard-statements see Section 16.
2.2 Label Elements:
Hazard pictograms

Signal Word: Danger

- Symbols: GHS08

Hazard phrases
May damage fertility or the unborn child.

Precautionary Phrases
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Use personal protective equipment as required.
If exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/international regulations.

Other hazards
May be mildly irritating to eyes and mucous membranes.
May be mildly irritating to respiratory system.

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 Section 3: - Composition/ Information on Ingredients
3.1 Substances
3.2 Mixtures:
This product does not contain any hazardous substances at the concentration limits given in Regulation (EC)
No. 1272/2008 and OSHA Hazard Communication Standard 29 CFR 1910.1200
Chemical Concentration CAS No. EC No. H-Statements Symbols
Cycloheximide <1% 66-81-9 200-636-0 H300, H360, H341, GHS06, GHS09
H401
Section 4 – First Aid Measures
4.1 General Information: In case of doubt, or when symptoms persist, seek medical attention.
Inhalation: If breathing is difficult, remove victim to fresh air and keep comfortable for
breathing.
Skin Contact: Remove contaminated clothing.
Wash affected area with plenty of soap and water.
If skin irritation or rash occurs: Get medical advice/attention.
Contaminated clothing should be laundered before reuse.
Ingestion: Rinse mouth with water (do not swallow).
Never make an unconscious person vomit or drink fluids.
If medical advice is needed, have product container or label at hand.
Eye Contact: If substance has gotten into eyes, immediately wash out with plenty of
water for at least 15 minutes. Irrigate eyes thoroughly while lifting eyelids
Seek medical advice if necessary.
Doctor Information: Show this sheet.
4.2 Most Important Symptoms The most important known symptoms are described in the labeling (see
Both Acute And delayed Section 2.2) and/or in Section 11.
4.3 Indication of any Treat symptomatically.
Immediate Medical Attention
and special Treatment needed
Section 5 – Fire Fighting Measures
5.1 Extinguishing Media In case of fire: use foam, Carbon Dioxide- CO2, or dry agent for extinction.
5.2 Special hazards arising from - Smoke from fires is toxic. Take precautions to protect personnel from
the substance or mixture exposure.
- Decomposition products may include carbon oxides, nitrogen, and
hydrogen chloride.
- May form explosive dust/air mixtures.
- See Section 10.
5.3 Advice for Firefighters - Keep container(s) exposed to fire cool, by spraying with water
- Wear chemical protection suit and positive-pressure breathing apparatus
- Wear protective clothing as per section
5.4 Additional Provisions May include carbon oxides.

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 Section 6 – Accidental Release Measures
6.1 Personal Precautions - Shut off all ignition sources.
- Use non-sparking hand tools.
- Remove contaminated clothing.
- Wear protective clothing as per Section 8.
- Wash thoroughly after dealing with spillage.
6.2 Environmental Precautions - Do not allow to enter public watercourses or public sewers.
- Avoid scattering in the environment.
6.3 Methods for Clean Up - Absorb spillage in inert material and shovel up.
- Place in sealable containers and label them.
- Ventilate the area and wash spill site after material pick-up is complete.
- Dispose of contaminated materials and wastes in accordance with
local/national/international regulation.
6.4 Reference to Other Sections See Section 7 for storage.
Section 7 – Handling and Storage
7.1 Safe Handling - Avoid contact with skin and eyes.
- Do not eat, drink, or smoke when using this product.
- Ensure adequate ventilation.
- Eyewash bottles should be available.
- Wash hands thoroughly after using this substance.
7.2 Conditions for safe storage, - Store in a well-ventilated place. Keep container tightly closed.
including any incompatibilities - Store in a dry place.
- Keep away from oxidizing substances.
- Store in a cool, dry condition in well-sealed receptacle, not exceeding 2-
8°C/ 35.6°- 46.4° F
7.3 Specific end use(s) For the selective enrichment of Listeria spp.
Section 8 – Exposure Controls/ Personal Protection
8.1 Control Parameters
There are no recommended or established controls for this product
8.2 Exposure Controls
- Eyewash bottles should be available.
- Engineering controls should be provided to prevent the need for ventilation.
- No respiratory protection is needed if ventilation/extraction is adequate, otherwise wear
approved respiratory protection, NIOSH N95 (US) or type FFP1 (EN143) dust masks.
- Wear protective gloves. The selected protective gloves have to satisfy the specifications of EU
Directive 89/686/EEC and standard EN 374.
- Wear safety glasses approved to standard for ANSI Z87 or EN 166.
- Wear suitable protective clothing in accordance with good chemical hygiene practices.
Section 9 – Physical and Chemical Properties
9.1 Information on basic physical and chemical properties
- Appearance: Gold to yellow color
- Physical State at 20°C: Liquid
- Odor: No information available
- pH: 7.3 ± 0.2
- Melting Point/Range: No information available
- Boiling Point/Range: Not determined.
- Flashpoint: No information available

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- Evaporation Rate: No information available
- Flammability: No information available
- Density: No information available
- Vapor Pressure: No information available
- Vapor Density: No information available
- Specific Gravity: No information available
- Solubility in water: No information available
- Partition Coefficient (n-Octanol/Water): No information available
- Autoignition Temperature: Product is not self-igniting
- Viscosity: No information available
- Explosive Properties: Product does not present an explosion hazard
- Oxidizing Properties: Product is not classified as an oxidizer
9.2 Other information - No information available.
Section 10 – Stability and Reactivity
10.1 Reactivity
No information available.
10.2 Chemical Stability
Considered stable under normal conditions of storage, handling and use.
10.3 Possibility of Hazardous Reactions
No hazardous reactions known if used for its intended purpose.
10.4 Conditions to Avoid
Keep away from heat and sources of ignition. Keep away from heat and sources of ignition.
10.5 Incompatible Materials
Incompatible with strong acids and oxidizers.
10.6 Hazardous Decomposition Products
Decomposition products may include carbon oxides, phosphorous compounds, chlorine, hydrogen chlorine and
sodium oxides.
Section 11 – Toxicological Information
11.1 Information on Toxicological Effects
Information on toxicological effects
- No experimental test data available for the mixture
- ATEmix = 726 mg/kg (oral)
Contact with skin
May cause redness and irritation in sensitive individuals.
Contact with eyes
May cause redness and irritation in sensitive individuals.
Ingestion
May cause irritation of the throat.
Inhalation
May cause coughing.
Carcinogenicity
Not listed in the National Toxicology Program (NTP) 13th Report on Carcinogens.
Not found to be a potential carcinogen in the International Agency for Research on Cancer (IARC) Monographs,
Volumes 1-112.
Not listed in OSHA standard 1910.1003 Carcinogens.
Mutagenicity
Suspected of damaging fertility.
Teratogenicity
Suspected of damaging the unborn child

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 Section 12 – Ecological Information
12.1 Toxicity
This product is not classified as hazardous to the environment under U.S. regulations.
12.2 Persistence and Degradability
No Information Available
12.3 Bioaccumulation Potential
No Information Available
12.4 Mobility in Soil
No Information Available
12.5 Results of PBT & vPvB assessment
Not a PBT according to REACH Annex XIII
PBT/vPvB assessment not available.
12.6 Other Adverse Effects
To the best of our knowledge, the properties of this material have not been fully evaluated. On available data;
substance is not harmful to the environment.
Section 13 – Disposal Considerations
13.1 Waste Disposal Disposal should be in accordance with local, regional, national, and/or
international regulations. Do not discharge into drains or the environment,
dispose to an authorized waste collection point. Do not reuse empty
containers.
13.2 Classification (REACH) Waste Codes in accordance with the European Waste Catalogue (EWC) are
origin-defined. Since this product is used in several industries, no Waste
Code can be provided by the supplier. The Waste Code should be determined
in arrangement with your waste disposal partner or the responsible
authority.
Section 14 – Transport Information
14.1 UN Number
Not classified as hazardous for transport
14.2 UN Proper Shipping Name
Not applicable
14.3 Transport hazard class(es)
Not applicable
14.4 Packing group
Not applicable
14.5 Environmental hazards
Not Classified
14.6 Special precautions for user
Not Classified
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC code
Not Classified
14.8 Domestic Surface Transport (US DOT)
- Proper Shipping Name: Not applicable
- DOT UN No.: Not applicable
- DOT Hazard Class: Not applicable
- DOT Packing Group: Not applicable
14.9 International Road/Rail (ADR/RID)
- Proper Shipping Name: Not applicable
- ADR UN No.: Not applicable
- ADR Hazard Class: Not applicable
- ADR Packing Group: Not applicable

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 - Tunnel Code: Not applicable
14.10 Ocean/Sea (IMO/IMDG)
- Proper Shipping Name: Not applicable
- IMDG UN No.: Not applicable
- IMDG Hazard Class: Not applicable
- IMDG Packing Group: Not applicable

Section 15 – Regulatory Information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture:
This Safety Data Sheet is provided in compliance with the EC Directive 1907/2006- 453/2010, WHMIS 2015
requirements as specified in the Hazardous Products Act (HPA) and the Hazardous Products Regulations (HPR),
and with the OSHA Hazard Communication Standard 29 CFR 1910.1200. Regulation (EC) No. 1272/2008 on the
classification, labelling and packaging of substances and mixtures (CLP Regulation) applies in Europe.
15.2 Chemical Safety Assessment
No information available
15.3 United States Regulatory Information
SARA 302
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 311/312
No SARA Hazards
15.4 Canadian Regulatory Information
Inventory Status
Domestic Substances List (DSL) Listed
Non-Domestic Substances List (NDSL) Not listed
Hazards not otherwise classified
PHNOC: Combustible dust > 1000lbs/454kg
Section 16 – Other Information
Date of Preparation: 1 March 2019
Revision: Rev. (1-10)

This safety data sheet has been designed in accordance with ANNEX II-Guide to the compilation of safety data
sheets of Regulation (EC) Nº 1907/2006 (Regulation (EU) Nº 453/2010, Regulation (EC) Nº 2015/830). This
document is believed to be correct, and shall be used only as a guide. These suggestions should not be
confused with state, municipal or insurance requirements, and constitute No Warranty. Microbiology
International shall not be held liable for any damage resulting from handling or from contact with the above
product. Minimal training is recommended to prevent industrial risks for staff using this product, in order to
facilitate their comprehension and interpretation of this safety data sheet, as well as the label on the product.

Manufactured by:
Microbiology International
5350 Partners Court
Frederick, MD 21703
P 301-662-6835 F 301-662-8096
1-800-EZMICRO (396-4276)

REV Description of Change Approved by Effective Date

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