COT No. 2
COT No. 2
COT No. 2
I. OBJECTIVES
A. Content The learners demonstrate an understanding of:
Standard 1. the information stored in DNA as being used to make proteins
2. how changes in a DNA molecule may cause changes in its
product
3. mutations that occur in sex cells as being heritable
B. Performance
Standard
C. Learning The learners should be able to:
Competency Explain how protein is made using information from DNA. (S10LTIIId-37)
D. Specific At the end of the lesson, the students should be able to:
Learning Outcome 1. Illustrate the central dogma of biology.
2. Transcribe DNA sequences into mRNA sequence.
3. Translate the mRNA codon into specific amino acid using the genetic
code.
II. CONTENT
Module 2: Heredity and Inheritance
Lesson 2: Protein Synthesis
Duration: 1 day
III. LEARNING
RESOURCES
A. Reference
s
1. Teacher’s Science TG pg. 203-309
Guide pages
2. Learner’s Science LM pg. 275-279
Material
pages
3. Textbook Evangelista, E. et.al. (2015). Science in Today’s World 10 . Quezon City.
pages SIBS Publishing House Inc., pp.
4. Additional
Materials
from
Leaning
Resource
(LR) Portal
IV.
PROCEDURES
Preliminaries - The students lead the prayer and arrange the seat afterwards.
- The teacher checks the attendance.
A. Elicit (5mins.) The teacher prepares a game called. “Pass the Cabbage”.
• Prior to the game the teacher prepares a cabbage model wherein each
paper contains a statement.
• As a song is played, the cabbage is passed on by the student to the
person next to her/him.
• When the music stops, the person holding the “cabbage” peels off the
paper and identify the difference between DNA and RNA. The students
will refer to the diagram below to answer the questions.
Questions:
3. Type of sugar
(Deoxyribose/Ribose)
4. Nitrogenous base pair
(Adenine/Thymine/Guanine/Cytosine/Uracil)
C. Explore (10
mins.) - The students will watch the video about Transcription and
Translation.
- Let the students be guided by the following questions:
a. What are the steps in making protein?
b. What are the three types of RNA?
c. Why is protein synthesis important?
The teacher divides the class into 3 groups. The group will be given a
comic strip showing a story about protein synthesis. After reading the
comic strip and guided by the video they watched, let them arrange
chronologically (1-6) the steps of transcription and translation. They will
also answer the guide questions below.
Guide Question:
1. How does transcription take place?
2. How does translation take place?
3. A construction worker brings hollow blocks to build a wall. What part
of translation resembles the construction worker’s job? What do the
hollow blocks represent?
D. Explain (20 Each group presents their output in front of the class.
mins.)
The students will discuss the diagram below showing how
transcription and translation is involved in making a protein
E. Elaborate (15 Through Think-Pair-Share, the students will play the “CODON
mins.) BINGO”.
(See attached activity sheets)
Order of
Order of Amino Acid
Order of bases in
bases in Coded into
bases in DNA mRNA
tRNA proteins.
(codon)
TAG AUC
CAT
ACA UGU
AAA
GAA CUU
Questions:
1. How does mRNA is converted into amino acids?
2. What is the role of tRNA in the process of protein synthesis?
G. Extend (5 Identify 5 diseases that might occur when protein synthesis goes
mins) wrong?
V. REMARKS
Additional References:
Protein Synthesis Song
https://www.youtube.com/watch?v=xzmMg337_UE
Video about Transcription and Translation
https://www.youtube.com/watch?v=8_f-8ISZ164
Prepared by:
RINA R. ROMANO
Teacher I
NOTED: