Autism Spectrum Book
Autism Spectrum Book
Autism Spectrum Book
AwURg nj gw¯Í‡®‹i ¯^vfvweK weKvkRwbZ Amyweav, hv‡K mgwš^Zfv‡e ÔAutism Spectrum DisorderÕ ev
ASD ejv nq ÒSpecturmÓ ej‡Z AwURg _vKv wkïi bvbv jÿY, `ÿZv Ges cÖwZeÜKZvi ch©vq A_ev
mxgve×Zvi e¨vcKZv‡K eySvq hv GKwU AwURg AvµvšÍ wkïi gv‡S _vK‡Z cv‡i| GUv ¯^í gvÎv †_‡K ¸iæZi
gvÎvq n‡Z cv‡i|
Diagnostic and Statistical Manual of Mental Disorders Fourth Edition- Text Revision (DSM-IV-TR)
Gi MvBW jvBb Abyhvqx GKwU wkï AwUR‡g AvµvšÍ wKbv Zv wbY©q Kiv nq| Manual wU m¤úªwZ cuvP ai‡bi
cÖwZeÜKZvi msÁv wba©viY K‡i‡Q| †hLv‡b A‡bK mgq AwURg‡K Pervasive developmental disorder Gi
mv‡_ GKxf‚Z K‡i ejv nq|
• AwURg wWRAW©vi (K¬vwmK AwURg)
• G¨vmcviRvi wWRAW©vi (GmcviRvi wm‡Ûªvg)
• cvi‡fwmf †W‡fjc‡g›Uvj wWRAW©vi bU Av`viIqvBR †¯úwmdvBW (PDD-NOS)
• †iUm& wWRAW©vi (†iU wm‡Ûªvg)
• PvBìûW wWmBw›Uª‡MÖkb wWRAW©vi (CDD)
Z‡_¨i GB cyw¯ÍKvwU †iU wm‡Ûªvg I CDD Gi Dci mswÿß Av‡jvPbv mn AwURg, G¨vmcviRvi wm‡Ûªvg,
PDD-NOS Gi Dci g~jZ Av‡jvKcvZ Ki‡e| AwURg Gi jÿYmg~n G‡KK wkïi †ÿ‡Î G‡KK iKg nq|
wKš‘ mvaviYfv‡e G‡`i‡K wZbwU fv‡M fvM Kiv hvq|
• mvgvwRK cÖwZeÜKZv
• †hvMv‡hvM ¯’vc‡b mgm¨v/cÖwZeÜKZv
• cybive„wËg~jK I GKB AvPiY evievi Kiv (Repetitive and Stereotyped)
AwURg Av‡Q Ggb wkï‡`i mvgvwRK I †hvMv‡hvM ¯’vc‡bi `ÿZv ¯^vfvweK wbqg Abyhvqx e„w× cvq bv|
AwffveKivB me©cÖ_g wkïi g‡a¨ A¯^vfvweK AvPiY jÿ¨ K‡i| GKB eq‡mi Ab¨vb¨ wkï‡`i mv‡_ wKQz
AvPiY Zzjbv Ki‡j AmsMwZUv mn‡RB †Pv‡L c‡o| wKQz wKQz †ÿ‡Î AwURg _vKv wkï‡`i cÖv_wgK ch©v‡q
e¨wZµg e‡j g‡b nq| A‡bK wkï Zv‡`i 1 eQi eqm c~Y© nevi Av‡MB †Kvb GKwU e¯‘i cÖwZ AZ¨vwaK
Avm³ nq, †Pv‡L †Pv‡L ZvKvq bv Ges Av`vb-cÖ`vb g~jK †Ljvq Ask wb‡Z Pvq bv| evev gv‡qi mv‡_ Av‡av
K_v ejv †hgb ev, ev-ey-ey-`v`v, gv gv e‡j bv| wKQz wKQz wkï cª_g 2/3 eQi ¯^vfvweKfv‡e †e‡o I‡V| wKš‘
Gi ci †_‡K Ab¨‡`i wel‡q AvMÖn nvwi‡q †d‡j, wbie n‡q hvq Ges mvgvwRK DÏxcbvi cÖwZ AvMÖn nvwi‡q
†d‡j A_ev cÖwZwµqvnxb _v‡K| ¯^vfvweK weKvkaviv K‡g Avmv ev m¤ú~Y©iƒ‡c nvwi‡q hvIqv‡K Ôwi‡MÖkbÕ
(Regression) bv‡g AwfwnZ Kiv nq- hv AwURg Av‡Q Ggb wKQz wkïi gv‡S †`Lv hvq|
D`vniY¯^iƒct GmKj wkïiv mvgvwRK Bw½Z/ms‡KZ¸‡jv eyS‡Z cv‡ibv| ÒG¨vmcviRvi wm‡ÛªvgÓ G AvµvšÍ
wkïiv Zv‡`i wcÖq welq m¤ú‡K© cÖvq GK bvMv‡i K_v e‡j| Zviv Ab¨ KvD‡K K_v ejvi my‡hvM w`‡Z Pvq bv
A_ev A‡b¨i cÖwZwµqvq fve‡jknxb _v‡K| AwURg Av‡Q Ggb wkï‡`i g‡a¨ fve cÖKv‡k A_©c~Y© fw½ M‡o bv
IVvq nVvr K‡i Zviv wPrKvi K‡i| A_ev †Kvb wKQz †Rvi K‡i ai‡Z cv‡i| hZw`b Zv‡`i wb‡R‡`i cÖ‡qvRb
†evSv‡bvi mwVK Dcvq †kLv‡bv bv nq, ZZw`b GB Ae¯’v Pj‡Z cv‡i| GmKj wkï‡`i eqm evovi mv‡_ mv‡_
Zviv Zv‡`i mxgve×Zv eyS‡Z cv‡i| GB m‡PZbZv Zv‡`i‡K DwØMœ ev welbœ Ki‡Z cv‡i|
mbv³KiY t
Av‡gwiKvb GKv‡Wwg Ae †cwWqvwUªK‡mi mycvwik µ‡g 18 Ges 24 gvm eq‡m my¯’ wkï †PKAv‡c mywbw`©ófv‡e
AwURg †¯úKUªvg wWRAW©vi mbv³KiYmn weKvkMZ mbv³KiY _vKv DwPr| AwURg †¯úKUªvg wWRAW©vi
mbv³KiY I WvqvM‡bvwmm GK bq| mbv³KiY Uzjmg~n cª_gavc wn‡m‡e e¨eüZ nq|
AwURg †¯úKUªvg wWRAW©vi mbv³Ki‡Y AwfÁ mvB‡KvjwR÷, wbD‡ivjwR÷, mvBwKq¨vwUª÷, ¯úxP †_ivwc÷ ev
Ab¨ †ckvRxexi GKwU Uxg-B g~j¨vqb Ki‡Z cv‡i| GB g~j¨vqb wkïi KM‡bwUf †j‡fj (wPšÍvi `ÿZv),fvlvMZ
`ÿZv Ges e¨envwiK `ÿZv (ˆ`bw›`b KvR¸‡jv wb‡R wb‡R Kivi eqm Dc‡hvMx `ÿZv¸‡jv †hgb- LvIqv,
Kvco civ I Uq‡j‡U hvIqv) ch©‡eÿY Kiv nq|
AwURg †¯úKUªvg wWRAW©vi GKwU RwUj wWRAW©vi hv gv‡S gv‡S Ab¨vb¨ †ivM ev wkLb mgm¨vi mv‡_
†`Lv †`Iqvi Kvi‡Y gw¯Í‡®‹i B‡gwRs, wRb cixÿv, ¯§„wZkw³, mgm¨v mgvavb I fvlvMZ `ÿZvi cixÿv
Kw¤úª‡nbwmf g~j¨vq‡bi AšÍf©y³ Kiv n‡q _v‡K| GB Kw¤úª‡nbwmf g~j¨vq‡bi Ask wn‡m‡e weKv‡k †cuxQv‡bv
wkï‡`i‡K kÖeY cixÿv I †jW cqRwbs cixÿv Kiv DwPZ|
AwURg †¯úKUªvg wWRAW©vi nIqvi cvkvcvwk wkï‡`i kÖe‡Yi mgm¨vI †`Lv w`‡Z cv‡i| AwURg †¯úKUªvg
wWRAW©v‡ii mvaviY jÿY¸‡jv †_‡KI (†hgb bvg WvK‡jI ZvKvq bv) g‡b n‡Z cv‡i Zviv ïb‡Z cvq bv
wKš‘ Zviv Avm‡j ïb‡Z cvq| GKUv wkï hw` A‡b¨i K_vq we‡kl K‡i Zvi bvg WvK‡j †Kvb mvov bv †`q,
Zvn‡j Zvi kÖeY mgm¨v Av‡Q wKbv Zv cixÿv Kiv AZ¨šÍ Riæwi| g~j¨vqb cÖwµqv cy‡iv Ux‡gi Kv‡Q cÖkœ Kivi
I civgk© cvIqvi Rb¨ DËg mgq| g~j¨vq‡bi djvdj Avcbvi mšÍv‡bi wPwKrmv I e¨e¯’vcbvi cwiKíbvq
mvnvh¨ Ki‡e| d‡jv-Avc cÖkœ wb‡q Kvi mv‡_ †`Lv Ki‡eb Zv Aek¨B wR‡Ám Ki‡eb|
Ny‡gi Amyweav/mgm¨v t
AwURg _vKv wkï‡`i Nyg Avmv ev Nywg‡q _vKvi A_ev Ny‡gi mgm¨v _v‡K| GB mgm¨vi Kvi‡Y Zv‡`i g‡bv‡hvM
K‡g hvq A_ev Kv‡Ri cÖwZ I Zv‡`i mÿgZv K‡g hvq Ges Zvi AvPi‡Y cÖfve †d‡j| Av‡iv D‡jøL¨, GB
Ny‡gi Amyweav; AwURg _vKv wkïi wcZv-gvZv m‡e©vcwi cy‡iv cwievi‡K wePwjZ/`ywðšÍvMÖ¯Í K‡i Ges Zv‡`i
mvwe©Kfv‡e (fMœ ¯^v¯’¨) Amy¯’ K‡i †Zv‡j| Ny‡gi mgm¨v Dck‡g AvPi‡Yi cwieZ©b KL‡bv KL‡bv mydj G‡b
†`q, †hgb: Ny‡gi mg‡qi iæwUb AbymiY Kiv A_ev weQvbvq hvevi iæwUb ˆZwi Kiv| wKQz wkï-Ny‡gi Jla
e¨envi Ki‡j fvj Nygvq, Ô†gjv‡UvwbbÕ GKwU ni‡gvb hv kix‡ii Nyg I RvMi‡Yi mvB‡Kj‡K wbqš¿Y K‡i | †h
†Kvb Jl‡ai gZ, Ô†gjv‡UvwbbÕ Gi I AcÖZ¨vwkZ cvk¦©cÖwZwµqv _vK‡Z cv‡i| ZvB Ny‡gi Amyweav wPwKrmvq
Ô†gjv‡UvwbbÕ e¨env‡ii c~‡e©B Avcbvi wkïi wPwKrm‡Ki mv‡_ K_v e‡j m¤¢ve¨ SuywK Ges DcKvi wel‡q †R‡b
wbb| AwURg _vKv Avcbvi wkïwUi mwVK AvPiY I Kv‡Ri DbœwZi Rb¨ AwURg _vKv wkïi Ny‡gi mgm¨vi
wPwKrmv Kiæb; G‡Z cwiev‡ii `ywðšÍvi cÖkgb n‡e|
eyw×cÖwZeÜKZv t
A‡bK AwURg _vKv wkïi gv‡S wKQz gvÎvq eyw× cÖwZewÜZv Av‡Q| Afxÿv cÖ‡qvM Ki‡j wKQz †ÿ‡Î ¯^vfvweK
mvg_© _vK‡jI, we‡kl K‡i eyw×e„Ëxq (wPšÍvg~jK) Kv‡R Ges fvlvi †ÿ‡Î Zviv `ye©j n‡q _v‡K| D`vniY¯^iƒc-
GKwU wkï hvi AwURg Av‡Q- †`‡L KvR Kivi †ÿ‡Î †hgb (GK‡Î cvRj †gjv‡bvi †ÿ‡Î) fvj K‡i wKš‘
fvlvi e¨envi K‡i †Kvb mgm¨v mgvav‡bi Kv‡R fvj bvI Ki‡Z cv‡i| wKš‘ hv‡`i G¨vmcviRvi wm‡Ûªvg
Av‡Q Zv‡`i KLbI ¯^vfvweK ev ¯^vfvwe‡Ki †P‡q †ewk fvlvMZ `ÿZv _v‡K Ges eyw× I fvlvi e¨env‡i †Kvb
wej¤^/†`wi nqbv|
wLuPzwbi mgm¨v t
AwURg _vKv wkï‡`i PviR‡bi g‡a¨ GKR‡bi wLuPzbx Av‡Q| Kv‡iv wLuPzbx ïiæ nq wkïKv‡j, Kv‡iv ïiæ nq
ˆK‡kv‡i| gw¯Í‡®‹i Af¨šÍ‡i Zwor cÖev‡ni A¯^vfvweK Kvh©µgB wLuPzbxi KviY:-
• LyeB ¯^í mg‡qi Rb¨ A‡PZb nIqv ev AÜKvi †`Lv|
• wLuPzbx nIqv wbqš¿Ynxbfv‡e mviv kix‡i SvKzwb Abyf‚Z nIqvq A_ev A¯^vfvweK bovPov|
• Starting spells.
bb KwgDwb‡Kej wWwRR K‡›Uªvj †cÖvMÖvg
7
KLbI KLbI Nyg Kg nIqv ev A‡bK R¡‡ii Kvi‡Y wLuPzbx n‡Z cv‡i| GKwU B‡j‡±ªvGb‡mdv‡jvMÖvg (BBwR),
†iKW© gw¯Í‡®‹i ˆe`y¨wZK Zi‡½i Kvh©µg cixÿv K‡i hv wkïi gv‡S wLuPzbxi Ae¯’v Rvb‡Z mvnvh¨ K‡i _v‡K|
wKQz wkïi A¯^vfvweK BBwR †iKW© _vK‡jI, wLuPzbxi mgm¨v bvI _vK‡Z cv‡i| wLuPzbx cÖwZ‡ivaK Jla w`‡q GB
wLuPzbxi wPwKrmv Kiv hvq| wKQz wLuPzbx cÖwZ‡ivaK Jla wkïi AvPi‡Y cÖfve †dj‡Z cv‡i; AwURg _vKv wkïi
AvPiY cwieZ©‡b wbweofv‡e bRi w`‡Z n‡e| †ewkifvM †ÿ‡Î, wPwKrmKMY
Kg gvÎvi Jla cÖ‡qvM K‡i Kvh©KvwiZv jÿ¨ K‡ib| wLuPzbx cÖwZ‡ivaK Jla
wLuPzbx nevi cÖeYZv‡K Kwg‡q †`q wKš‘ mevi †ÿ‡Î Zv cÖwZ‡iva Kiv hvq bv|
†d«RvBj G· wm‡Ûªvg t
†d«RvBj G· wm‡Ûªvg GKwU †R‡bwUK Amyweav Ges †ewkifvM eyw×cÖwZewÜZvi
mvaviY aiY| hv eskMZfv‡e cÖKvwkZ, jÿY¸‡jv AwUR‡gi mv‡_ wg‡j
hvq| GB bvgwU G·‡µv‡gvR‡gi GKwU Ask †_‡K G‡m‡Q †hLv‡b ÿwZMÖ¯Í
AskwU cÖKvwkZ n‡q‡Q Ges hv LyeB bvRyK| (†d«RvBj gvB‡µv‡¯‹v‡ci
mvnv‡h¨ †`Lv hvq)| †d«RvBj G·‡µv‡gvRg cwiewZ©Z nq, hv‡K wgD‡Ukb
e‡j hv GKwU wR‡b _v‡K| Rwo‡q aiv ev ¯úk© Kiv cQ›` K‡ibv
wKQz e¨w³i mvgvb¨ AvKv‡ii GKvU wgD‡Ukb nq hvi †Kvb jÿY _v‡K bv| Avevi Ab¨ hv‡`i eo AvKv‡ii
GKwU wgD‡Ukb nq Zv‡`i ¸iæZi jÿY cÖKvwkZ nq| AwURg wkï‡`i cuwPkR‡bi gv‡S GKR‡bi GB
wgD‡Ukb _v‡K hvi KviY †d«RvBj G· wm‡Ûªvg|
AwURg _vKv wkïi †d«RvBj G· wm‡Ûªvg cixÿv Ki‡Z n‡e| we‡kl K‡i evev-gv hw` cieZ©x mšÍvb wb‡Z
Pvb| cwiev‡ii Ab¨vb¨ m`m¨iv hvivI mšÍvb †bevi cwiKíbv Ki‡Qb ZvivI †d«RvBj G· wm‡Ûªvg cixÿv
K‡i wb‡Z cv‡ib| Av‡iv Rvb‡Z The Eufice Kennedy Shriver National Institute of Child Health and
Human Development Gi I‡qemvBU †`L‡Z cv‡ib| http://www.nichd.nih.gov/health/topics/ fragile-
X-syndrome.efm.
wUD‡eivm †¯‹‡j‡ivwmm t
GwU GKwU `yj©f †R‡bwUK Amyweav hv gw¯Í‡®‹ ev Ab¨ A‡½ bb K¨vbmvivm wUDgvi ˆZwi K‡i| 1 †_‡K 4%
AwURg _vKv wkïi gv‡S GB wUD‡eivm †¯‹‡j‡ivwmm _vK‡Z cv‡i| Gi KviY n‡”Q, †R‡bwUK/eskMwZ
wgD‡Ukb; eyw×cÖwZewÜZv, wLuPzbx, Ab¨vb¨ kvixwiK I gvbwmK ¯^v¯’¨MZ mgm¨vi mv‡_I Gi m¤ú„³Zv _vK‡Z
cv‡i| wPwKrmv wb‡q m¤ú~Y© Av‡ivM¨ jvf Kiv bv †M‡jI Gi A‡bK¸‡jv jÿ‡Yi wPwKrmv Kiv m¤¢e|
†c‡Ui mgm¨v t
AwURg _vKv wkï‡`i AwffveKMY cÖvqktB Zv‡`i wkï‡`i nR‡gi Amyweav, †c‡Ui e¨v_v, Wvqwiqv, †KŠôKvwVb¨,
M¨v÷ªvBwmm (†c‡Ui M¨vm), ewg A_ev Bloating wel‡q Awf‡hvM K‡ib ev Rvbvb| AwURg _vKv wkïi Rb¨
†Kvb Lvev‡ii cÖwZ GjvwR© Gi GKwU KviY| wkïi †c‡Ui mgm¨vq welqwU h‡_ó cwi¯‹vifv‡e Rvbv bv _vK‡j
GKRb †c‡Ui †ivM we‡kl‡Ái civgk© wbb, wZwb Avcbv‡K Gi KviY I mwVK wPwKrmvi civgk© w`‡Z cvi‡eb|
wKQz mgxÿvi cÖwZ‡e`b †`Lv †M‡Q †h AwURg _vKv wkï‡`i †c‡Ui mgm¨vi jÿY _vK‡jI GUv me AwURg
_vKv wkïi Rb¨ cÖ‡hvR¨ bq| †hgb: wg‡b‡mUvi mv¤úªwZK GKwU M‡elYvq †`Lv †M‡Q AwURg _vKv wkïwUi
kvixwiK I AvPiYMZ Amyweavi mv‡_ Zvi Lvev‡ii m¤ú„³Zv Av‡Q (D`vniY j¨vK‡UvR MÖn‡Y Amyweav A_ev
wKQz wbw`©ó Lvevi MÖnY/Bbwm÷) hv Zvi Rb¨ †KŠôKvwVb¨ ˆZwi K‡i| GB M‡elYvwU civgk© †`q †h, AwURg
_vKv †hme wkï‡`i †c‡Ui gv‡S mgm¨vwU A¯úó (AvÛvi jvBwqs) Av‡Q, wKš‘ Zv‡`i AvPiY †c‡Ui mgm¨vi
jÿY cÖKvk Ki‡Q †hgbt hviv GKwU wbw`©ó ai‡Yi Lvevi Lvq hv h‡_ó cwigv‡Y Avukhy³ bq A_ev Zij Lvq-
Jl‡ai e¨envi t
wKQz wKQz Jla Avcbvi wkïi wKQz DcmM© Kgv‡Z mvnvh¨ K‡i hv Zv‡K evwo‡Z ev ¯‹z‡j A‡bK mgm¨vq
†dj‡Q| Av‡iv A‡bK Jla †me‡bi civgk© †`Iqv nq †h¸‡jv‡K Ad †j‡ej (off-label) Jla e‡j hvi A_©
n‡jv †h Jla¸‡jv BDGm dzW A¨vÛ WªvM GWwg‡b‡÷ªkb (FDA) KZ…©K †Kv‡bv we‡kl Kvi‡Y ev †Kv‡bv we‡kl
e¨w³e‡M©i e¨env‡ii AbygwZ †`Iqv nqwb| wPwKrmKiv mvaviYZt Ad †j‡ej (off-label) Jla †me‡bi
civgk© w`‡q _v‡Kb hLb ASD Gi mv‡_ mswkøó Av‡iv wKQz AvPiY _v‡K hvi Jla¸‡jv Aby‡gvw`Z| A_ev †hB
Jla¸‡jv cÖvß eq¯‹ Ges eo AwUw÷K wkï‡`i †ÿ‡Î e¨envi K‡i Kvh©Kix djvdj cvIqv †M‡Q| wPwKrmKiv
Ad †j‡ej Gi Jla Aí eqmx †ivMx‡`i A‡bK mgq w`‡q _v‡Kb| GB Jla¸‡jv ASD wkï Ges wK‡kvi‡`i
†ÿ‡Î KZUzKz wbivc` I Kvh©Kix †mB wel‡q wbwðZ nIqvi Rb¨ Av‡iv cÖPzi M‡elYvi cÖ‡qvRb| A`¨ewa, †h
Jla¸‡jv AwUw÷K e¨w³‡`i †ÿ‡Î e¨envi Kivi Aby‡gv`b †c‡q‡Q Zv nÕj A¨vw›U mvB‡KvwUK&m wim‡cwiWb
Ges G¨vwi wcÖcvRj| D³ Jla¸‡jv 5-16 eQ‡ii AwUw÷K wkï‡`i weiw³Ki AvPiY h_v AvµgYvZ¥K
AvPiY, wb‡RK AvNvZ Kiv, wPrKvi †PuPv‡gwP Kiv, BZ¨vw` wbqš¿‡Y mvnvh¨ K‡i| wKQz wKQy Ad †j‡ej Jla
†h¸‡jv AwUw÷K wkï‡`i Rb¨ e¨envi Kiv nq †m¸‡jv n‡jvt
Gw›UmvB‡KvwUK Jla t
mvaviYZt Zxeª gvbwmK Amy¯’Zv †hgb wm‡Rvwd«wbqvq e¨eüZ nq| GB Jla¸‡jv mvaviYZ: AwUw÷K wkïmn
Ab¨vb¨ wkï‡`i AvMÖvmx AvPiY, Ab¨vb¨ Zxeª e¨envwiK mgm¨v wbim‡b mnvqZv K‡i| GQvov GB RvZxq
Jla¸‡jv cybive„wËg~jK AvPiY, AwZ PvÂj¨Zv, gb‡hv‡Mi mgm¨v wbevi‡YI mnvqZv K‡i|
• AwURg ˆewkó¨m¤úbœ wkïiv mvaviYZ: Ab¨vb¨ ¯^vfvweK wkï‡`i g‡Zv GKBfv‡e Jl‡a cÖwZwµqv K‡i bv|
• Avcwb Avcbvi wkïi Rb¨ †mB me wPwKrmK‡`i mv‡_ †hvMv‡hvM Ki‡eb hv‡`i AwUw÷K wkï‡`i
wPwKrmv Kivi AwfÁZv i‡q‡Q|
• Avcbvi wkïi mgm¨vMÖ¯Í DcmM© wbqš¿Y Kivi †ÿ‡Î Jla †`evi cÖ‡qvRb n‡j wPwKrmK‡K memgq
Jla Kg gvÎv †_‡K ïiæ Kiv DwPZ|
• Avcbvi wkïi wPwKrmK‡K Aek¨B wkï‡K †meb Ki‡Z †`Iqv Jl‡ai cvk¦©cÖwZwµqvi K_v wR‡Ám
Ki‡eb Ges Avcbvi wkïi Jla †me‡b wK cÖwZwµqv n‡”Q ZvI wjwce× Ki‡eb|
• wPwKrm‡Ki DwPZ n‡e Jl‡ai djvdj jÿ¨ Kivi Rb¨ wbqwgZ Avcbvi wkï‡K †`Lv|
• Avcbvi wkïi AwUR‡gi wPwKrmvi Rb¨ Avcbvi Kv‡Q A‡bK¸‡jv my‡hvM Av‡Q|
• Z‡e ˆeÁvwbK cixÿv wbixÿvq cÖgvwYZ n‡q‡Q †h me¸‡jv mgvb Kvh©Kix bq|
AwURg †Kb nq ?
we‡klÁ‡`i g‡Z GLbI AwUR‡gi my¯úó †Kv‡bv KviY ev KviYmg~n Rvbv hvqwb| Z‡e M‡elYvq aviYv Kiv
n‡”Q †h GB wel‡q eskMwZ (†R‡bwUKm&) Ges cwi‡e‡ki GKwU ¸iæZ¡c~Y© f‚wgKv i‡q‡Q|
eskMwZ t
Awfbœ hgR‡`i (Identical Twins) †ÿ‡Î hv‡`i †R‡bwUK ms‡KZ (Genetic code) ûeû GK _v‡K,
Zv‡`i GKRb hw` AwUR‡g AvµvšÍ nq, Avi GKR‡bi AwURg nevi SzuwK cÖwZ 10 R‡bi wfZi 9 R‡bi
_v‡K| †Kvb cwiev‡i hw` GKwU mšÍv‡bi AwURg _v‡K, cieZx© mšÍvb‡`i kZKiv 35 fvM †ÿ‡Î AwURg
nevi SzuwK _v‡K| M‡elKiv †hB wRb¸‡jv AwUR‡gi Rb¨ `vqx ev AwURg nevi SzuwK‡K evwo‡q †`q, †mB
wRb¸‡jv‡K mbv³ Kiv ïiæ K‡i‡Qb|
Z‡e GLbI ch©šÍ ˆeÁvwb‡Kiv SzuwKc~Y© wRb¸‡jv mwVKfv‡e mbv³ Kivi e¨vcv‡i c~Y© mdjZv AR©b Ki‡Z cv‡ib
wb| GB wel‡q Av‡iv Z_¨ Rvb‡Z PvB‡j ÒAwUR‡gi mv‡_ Av‡iv wK wK GwKf‚Z Ae¯’v _vK‡Z cv‡iÓ LÛwU
(Chapter) †`Lyb| †hLv‡b Fragile X syndrome Ges Tuberous sclerosis Gi wel‡q eY©bv †`Iqv Av‡Q|
†ewki fvM AwURg ˆewkó¨m¤úbœ e¨w³‡`i cvwievwiK BwZnv‡m Ab¨ †Kvb AwUw÷K e¨w³i mÜvb cvIqv hvq
bv| ZvB aviYv Kiv n‡”Q †h G‡jv‡g‡jvfv‡e ev nVvr K‡i wKQz weij †R‡bwUK cwieZ©b/iƒcvšÍi (mutation)
GKRb e¨w³i AwUR‡g AvµvšÍ nIqvi SzuwK evwo‡q †`q| †R‡bwUK Z‡_¨i †h †Kv‡bv cwieZ©b‡KB †R‡bwUK
iƒcvšÍi ev Genetic mutation ejv nq| GB iƒcvšÍi eskMZ n‡Z cv‡i, Avevi KL‡bv Gi †Kv‡bv KviY
Ly‡R cvIqv hvq bv| †R‡bwUK iƒcvšÍi/cwieZ©b KL‡bv DcKvix KL‡bv ÿwZKviK Avevi KL‡bv Gi †Kvb
cÖfve c‡o bv| A‡bK †ÿ‡Î eskMwZi Kvi‡Y AwUR‡gi SuywK _vK‡jI Zv mKj wkïi †ejvq cÖ‡hvR¨ bq|
wKfv‡e GKvwaK wR‡bi mswgkÖY Ges cwi‡ekMZ Dcv`v‡bi wgkÖ cÖfve AwUR‡gi SzuwK evwo‡q w`‡”Q, GB
welqwU Av‡iv fv‡jvfv‡e †evSvi Rb¨ A‡bK M‡elKiv A‡bK †ewk ¸iæZ¡¡ w`‡”Qb|
bb KwgDwb‡Kej wWwRR K‡›Uªvj †cÖvMÖvg
16
cwi‡ekMZ Dcv`vb t
gvbe‡`‡ni evB‡i hv wKQz Av‡Q wPwKrmv kv‡¯¿ Zv‡K ejv nq Òcwi‡ekÓ| evqy †_‡K Avgiv k¦vm-cÖk¦vm †bB,
cvwb cvb Kwi, †Mvmj Kwi, Lvevi LvB, Jla †meb Kwi, Ggb Av‡iv A‡bK wRwbm Avgv‡`i kix‡ii ms¯ú‡k©
Av‡m Gi meB cwi‡e‡ki Ask| gv‡qi M‡f© _vKv Ae¯’vq Avgv‡`i PZzc©vk wQj Avgv‡`i cwi‡ek, †hLv‡b
Avgv‡`i gv‡qi ¯^v¯’¨ Avgv‡`i cÖviw¤¢K MVb I weKvk‡K cÖfvweZ K‡i‡Q| M‡elKiv cwi‡e‡ki bvbv Dcv`vb
wb‡q cixÿv wbixÿv Ki‡Qb †hgb cvwievwiK ¯^v¯’¨MZ Ae¯’v, wcZv-gvZvi eqm, Ges Av‡iv Ab¨vb¨ RbmsL¨v
ZvwË¡K Dcv`vb, welv³ c`v‡_©i ms¯ú‡k© Avmv Ges Mf©ve¯’vq Ges cÖmeKvjxb RwUjZv| aviYv Kiv n‡”Q †h
†R‡bwUK Kvi‡Yi gZB cwi‡e‡ki GKvwaK Dcv`vb AwUR‡g AvµvšÍ nIqvi SzuwK m„wó K‡i| †R‡bwUK Kvi‡Yi
gZB cwi‡e‡ki Dcv`vb GKKfv‡e AwUR‡gi SzuwK m„wó K‡i LyeB Kg| †ewki fvM gvby‡liB cwi‡e‡ki
SzuwKc~Y© Dcv`v‡bi Kvi‡Y AwURg nqbv| b¨vkbvj Bbw÷wUDU Ae Gbfvqib‡g›Uvj †nj_& mvBÝ GB wel‡q
M‡elYv cwiPvjbv Ki‡Qb| Av‡iv Z_¨ Rvbvi Rb¨ I‡qemvBU †`Lyb www.niehs.nih.gov/health/topics/
conditions/ autism/index.com ˆeÁvwbKiv AbymÜvb Pvjv‡”Qb Kxfv‡e wKQz cwi‡e‡ki Dcv`vb wKQz wRb‡K
cÖfvweZ Ki‡Q, Zv‡`i ¯^vfvweK Kvh©µg‡K mwµq ev wbw¯Œq Ki‡Q| GB cÖwµqv‡K ejv nq epigenetics.
GB welqwU Kxfv‡e AwURg nq Ges Kxfv‡e Gi cwieZ©bI Av‡m †mB wel‡q M‡elK‡`i Kv‡Q bZzb Z_¨
Avwe¯‹v‡ii m¤¢vebvi `yqvi D‡b¥vPb Ki‡Q|
AwURg †¯úKUªvg wWRAW©vi ˆewk‡ó¨i wkï‡K Avwg Kxfv‡e mnvqZv Ki‡Z cvwi ?
Avcbvi wkïwU AwURg †¯úKUªvg wWRAW©vi WvqvM‡bvwm‡mi ci Zvi cÖ‡qvRbxq †mev/cwiPh©v I wk¶v w`‡Z
Avcwb e¨_© ev cÖ¯‘Z bb g‡b n‡Z cv‡i| †R‡b ivLyb, A‡bK¸‡jv wPwKrmv c×wZ, mvgvwRK †mev I Kvh©µg
Ges Ab¨vb¨ wi‡mvm© Av‡Q hv mnvqZv Ki‡Z cv‡i| wKQy civgk© hv Avcbv‡K I Avcbvi mšÍvb‡K mvnvh¨ Ki‡Z
cv‡i:
• ¯^v¯’¨ †mev cÖ`vbKvix I wk¶K‡`i mv‡_ me K‡_vcK_b, mfv Ges Ab¨vb¨ Z‡_¨i Dr‡mi †iKW©
ivLyb| hv wewfbœ wPwKrmv c×wZ g‡b ivL‡Z I Avcbvi mšÍv‡bi Rb¨ mwVKwU †e‡Q wb‡Z Avcbv‡K
mnvqZv Ki‡e|
• Wv³v‡ii wi‡cvU©mg~n Ges Avcbvi mšÍv‡bi g~j¨vq‡bi †iKW© ivLyb| GB Z_¨ Zvi Dc‡hvMx we‡kl
Kvh©µ‡g †h‡Z mvnvh¨ Ki‡Z cv‡i|
• Avcbvi GjvKvq we‡kl Kvh©µg m¤ú‡K© Rvb‡Z ¯’vbxq GW‡fv‡Kmx AwURg cÖæc _vK‡j Zv‡`i mv‡_
†hvMv‡hvM Kiæb|
• GKwU B›Uvi‡fbkb cwiKíbv ˆZwi Ki‡ZI Ab¨vb¨ ¯’vbxq wi‡mv‡m©i mÜvb †c‡Z Ges Avcbvi
GjvKvq GKRb AwURg we‡klÁ Lyu‡R †ei Ki‡Z Avcbvi wkïi wPwKrmK, ¯‹zj KZ…©c¶ ev AwURg
mv‡cvU© MÖæc Gi mv‡_ Avjvc Kiæb|
bb KwgDwb‡Kej wWwRR K‡›Uªvj †cÖvMÖvg
19
AwURg †¯úKUªvg wWRAW©vi ˆewk‡ó¨i wK‡kvi‡`i‡K †evSv/Dcjw× Kiv t
wK‡kvi eqmUv AwURg †¯úKUªvg wWRAW©vimn †h †Kv‡bv evošÍ wkïi Rb¨B gvbwmK Pvc I weåvwšÍKi mgq|
ˆK‡kv‡ii mgq wK‡kvi-wK‡kvixiv A‡b¨i e¨vcv‡i Ges Zv‡`i mv‡_ m¤ú‡K©i e¨vcv‡i A‡bK †ewk m‡PZb n‡q
hvq| †ewkifvM wK‡kv‡iiv gy‡Li eªY, wb‡R‡`i RbwcÖqZv, cix¶vi b¤^i/†MÖW/†Q‡j‡g‡q eÜzi mv‡_ m¤úK©
BZ¨vw` wb‡q wPwšÍZ _v‡K| AwURg †¯úKUªvg wWRAW©vi ˆewk‡ó¨i wK‡kv‡iiv Zv‡`i mgeqmx‡`i †_‡K Zviv
Avjv`v GB e¨vcviwU eyS‡Z †c‡i Kó cvq| GB e¨vcv‡i m‡PZbZv wKQy msL¨K wK‡kvi‡`i‡K bZzb K‡i
AvPiY wkL‡Z I Zv‡`i mvgvwRK `¶Zv evov‡Z m‡Pó K‡i| Ab¨‡`i †¶‡Î Abyf~wZ‡Z AvNvZ I A‡b¨i mv‡_
†hvMv‡hv‡Mi e¨_©Zv welbœZv, DwØMœZv ev Ab¨vb¨ gvbwmK mgm¨vi m„wó Ki‡Z cv‡i| wKQy wKQy AwURg †¯úKUªvg
wWRAW©vi ˆewk‡ó¨i wK‡kv‡iiv AwaKZi AwUw÷K ev AvµgYvZ¥K AvPi‡Yi gva¨‡g ˆK‡kv‡i Zv‡`i gvbwmK
Pvc I weåvwšÍ cÖKvk K‡i _v‡K| AwURg †¯úKUªvg wWRAW©v‡ii wK‡kvi‡`iI ˆK‡kv‡i Zv‡`i †h kvixwiK
cwieZ©b I †hŠb cwic°Zv Av‡m Zv †evSvi Rb¨ mnvqZv `iKvi|
Avcbvi wK‡kvi mšÍbwUi mvg‡j/Lvc LvB‡q wb‡Z mgm¨v n‡”Q g‡b n‡j Zvi wPwKrmK‡`i mv‡_ †hvMv‡hvM
Kiæb Ges m¤¢ve¨ †Kv‡bv gvbwmK mgm¨vi Rb¨ wK Ki‡Z cv‡ib Avjvc Kiæb| AvPiYMZ †_ivcx I IlyacÎ
mvnvh¨ Ki‡Z cv‡i|