Nervous System

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Anaphy Lecture

FUNCTIONS OF THE NERVOUS SYSTEM


1. Maintaining Homeostasis
2. Receiving Sensory Input
3. Integrating Information
4. Controlling muscles and glands
5. Establishing and maintaining mental activity

TWO MAIN PARTS OF THE NERVOUS SYSTEM


Central Nervous System
receives information from and sends information to the body.
• Brain
• Spinal chord

Peripheral Nervous System


Responsible for detecting stimuli in and around the body and sending that
information to the CNS and then communicating messages from the CNS
to the body.

SENSORY DIVISION

Afferent Division
• transmits electrical signals from specialized receptors in the
body toward the CNS. For this reason, the sensory division is also
called the afferent division

MOTOR DIVISION

Efferent Division
• transmits electrical signals from the CNS to effector organs,
such as muscles and glands. Thus, the motor division is also called
the efferent division
Anaphy Lecture
TWO BRANCHES

SOMATIC
• the voluntary division of the motor division. It allows you to
decide to move your skeletal muscles, such as when raising your
hand to ask a question, or to stand and walk across the room.
AUTONOMIC
• the involuntary division of the motor division. It regulates
activities without our conscious control such as contractions of
cardiac muscle and smooth muscle and secretions by certain
glands. For example, your heart rate increases when you hear an
unexpected loud noise that startles you.

Difference Between Sympathetic and Parasympathetic

Sympathetic
• Primary process is to stimulate the body’s “fight-or-flight”
response
Parasympathetic
• Responsible for stimulation of “rest-and-digest” or “feed-and-
breed” activities
Enteric
• Consists of neuronal networks within the wall of the digestive
tract

NERVOUS SYSTEM
Peripheral Nervous System Central Nervous System
Autonomic Nervous Somatic Nervous
System System
Sympathetic Nervous Parasympathetic
Enteric Nervous System
System Nervous System

CELLS OF THE NERVOUS SYSTEM


The two cell types that make up the nervous system, neurons and glial cells,
work together to monitor the body’s environment and make changes when
needed.
Anaphy Lecture
Neurons
the electrically excitable cells of the nervous system. There are three
parts to most types of neuron: (1) a neuron cell body, (2) dendrites, and
(3) a single axon.
A NEURON CELL BODY
• Performs the typical functions of any cell, such as protein
synthesis and packaging of proteins into vesicles.
DENDRITES
• Are extensions of the cell body and receive information from
other neurons or from sensory receptors.
AXONS
• In most neurons, a single axon arises from a cone-shaped area of
the neuron cell body called the axon hillock.

TYPES OF NEURONS: Functional Classification

1. Sensory Neurons
• Affector
2. Interneurons
• In the CNS
3. Motor Neurons
• Effector

TYPES OF NEURONS: Number of Dendrites

MULTIPOLAR NEURON

They have many dendrites and a single axon


The dendrites vary in number and in their degree of branching
Most of the neurons within the CNS and motor neurons of the PNS are
multipolar

BIPOLAR NEURON

They have two processes


• One dendrite and one axon
The dendrite is often specialized to receive the stimulus, and the axon
conducts action potentials to the CNS
Anaphy Lecture
Bipolar neurons are located in some sensory organs, such as in the retina
of the eye and in the nasal cavity

PSEUDO-UNIPOLAR NEURON

Appears to have an axion and n dendrites


These neurons have a single process extending from the cell body, which
divides into two branches a short distance from the cell body
The TWO BRANCHES function as a single axon. One branch, the
peripheral process, extends to the periphery and has dendrites. These
dendrites either act as a sensory receptor or communicate with a sensory
receptor
The OTHER BRANCHES, called the central process extends to the CNS

ANAXONIC NEURON

Has multiple branches but no axons


Do not have axons and only have dendrites projecting from their cell body
Found within the brain and retina, these neurons communicate using only
graded potentials and not action potentials

Glial/Neuroglia
Glial cells are support cells for neurons. There are four types of CNS glial
cells: (1) astrocytes, (2) ependymal cells, (3) microglia, and (4)
oligodendrocytes.

TYPES OF NEUROGLIA: Central Nervous System

ASTROCYTES
• star-shaped glial cells with cytoplasmic processes extending
from their cell bodies. These extensions widen and spread out to
form foot processes, which cover the surfaces of blood vessels
EPENDYMAL CELLS
• line the ventricles (cavities) of the brain and the central canal
of the spinal cord
• Some ependymal cells have patches of cilia that assist in the flow
of cerebrospinal fluid.
Anaphy Lecture
• Ependymal cells also have long processes at their basal surfaces
that extend deep into the brain and the spinal cord and seem, in
some cases, to have astrocyte-like functions.

MICROGLIA
• Are CNS-specific immune cells derived from the same embryonic
tissue as other immune cells within the blood
OLIGODENDROCYTES
• Extensions from oligodendrocytes form part of the myelin
sheaths of several axons within the CNS

TYPES OF NEUROGLIA: Peripheral Nervous System

SATELLITE CELLS
• Surround neuron cell bodies in sensory and autonomic ganglia
• Besides providing support and nutrition to the neuron cell bodies,
satellite cells protect neurons from heavy-metal poisons, such as
lead and mercury, by absorbing them and reducing their access
to the neuron cell bodies.
SCHWANN CELLS
• Forms the myelin sheaths
• Outermost layer of the Schwann cell is called the neurilemma. It
contains majority of the Schwann cell cytoplasm, nucleus and
organelles.

CEREBRAL CORTEX
White Matter
White appearance
Gross inspection
Inside
White matter of the brain between the cortex and the nuclei is the
cerebral medulla. This term should not be confused with medulla oblongata.
The cerebral medulla consists of tracts that connect areas of the cerebral
cortex to each other or to other parts of the CNS
Anaphy Lecture
Gray Matter
Outside
Gray matter on the outer surface of the cerebrum is the cerebral cortex,
and clusters of gray matter deep inside the brain are nuclei. The cerebral
cortex contains a number of neuron types, named largely for their shape,
such as fusiform cells, stellate cells, and pyramidal cells

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