Material safety data sheet

DISSOLVINE NA2
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING
Product Identifier
Ethylenediaminetetraacetic acid, disodium salt, dihydrate, approx. 100%
Supplier
Akzo Nobel Chemicals (Ningbo) Co., Ltd.
No.1801,Mid-Haitian Road, Xiepu Town, Zhenhai District,315204, Ningbo
Tel: +86 21 2216360
Emergency telephone
AkzoNobel Chemicals-Deventer-NL
T +31 570 679211
F +31 570 679801
China National Registration Center for Chemicals
phone +86 532 8388 9090 (fax +86 532 8378 6550)
Relevant identified uses of the substance or mixture
-adding chelates to liquid and solid formulations (EU : ES2)
-use in industrial processes in which the chelates are consumed (EU :ES3)
-Industrial use / Professional use :
-in spraying formulations (EU :ES4)
-in non-spraying formulations (EU :ES5)
-in building and construction (EU :ES6)
-use : in consumer products (EU :ES7)
Date of last issue / Revision number
2011/02/01 / 1.00

2. HAZARDS IDENTIFICATION
Classification according to 67/548/EEC as amended
Xn; R20; Harmful by inhalation.

GHS classification
Description Applicable
Acute toxicity (inhalation) category 4
Acute toxicity (oral) category 5

Pictogram(s) (GHS)

Signal word/Hazard statement(s) (GHS)

Code Description
Signal word: WARNING
H303. May be harmful if swallowed.
H332. Harmful if inhaled.

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Material safety data sheet

DISSOLVINE NA2
Precautionary statement(s) (GHS)
Code Description
P261a. Avoid breathing dust .
P271. Use only outdoors or in a well-ventilated area.
P304+P340. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable
for breathing.
P308+P313. IF exposed or concerned: Get medical advice/attention.

3. COMPOSITION/INFORMATION ON INGREDIENTS
Information on hazardous ingredients
Chemical description
Ethylenediaminetetraacetic acid, disodium salt, dihydrate, approx. 100%
Composition / information on ingredients
Number % w/w CAS-number Chemical name
1 89 - 91 000139-33-3 Ethylenediaminetetraacetic acid, disodium salt

Other information
Balance: water

4. FIRST AID MEASURES

Most important symptoms and effects
No typical symptoms and effects known.
Description of first aid measures
General
IF exposed or concerned: Get medical advice/attention.
Inhalation
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Skin
Take off contaminated clothing immediately. Wash immediately with soap and water. Launder clothes before
reuse.
Eye
Rinse thoroughly with plenty of water. Eyelids should be held away from the eyeball to ensure thorough rinsing.
Seek medical advice if irritation persists.
Ingestion
No special measures required.
Indication of any immediate medical attention and special treatment needed
No additional information available

5. FIRE-FIGHTING MEASURES
Extinguishing media
waterspray, foam, Carbon dioxide, dry chemical powder
Unsuitable extinguishing media
none known.
Hazardous decomposition / combustion products
Nitrous gases may be produced
Protective equipment
Use self-contained respiratory equipment.
Fire and explosion hazard
In case of fire and/or explosion do not breathe fumes.

6. ACCIDENTAL RELEASE MEASURES

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Material safety data sheet

DISSOLVINE NA2
Personal precautions
For personal protection see Section 8
Environmental precautions
Collect as much as possible in a clean container for (preferable) reuse or disposal.
Methods and material for containment and cleaning up
Flush remainder with water ( Absorb the remainder with e.g. vermiculite ). See section 13 .

7. HANDLING AND STORAGE

Precautions for safe handling
Avoid dust generation. Avoid breathing dust .
Use only outdoors or in a well-ventilated area.
Fire and explosion prevention
In certain concentrations the product may form an explosive dust-air mixture.
Conditions for safe storage
none known.
Other information
Protect product from moisture and wet air. Keep container tightly closed and dry.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters
for additional information : see : Annex.
Avoid dust generation.
Personal protection
Respiratory
for additional information : see : Annex.
In case of dust formation use dust mask. Dust exposure limits have to be respected.
Hand
for additional information : see : Annex.
For permanent (>480 minutes), full contact use, 100% nitrile gloves conforming to EN 374, e.g. KCL Dermatril
740 are recommended.
If used under conditions other than given above it is recommended that a supplier of CE approved gloves is
contacted.
These recommendations are only applicable to the chemical as supplied by Akzo Nobel; if mixed with or
dissolved in other substances please contact a supplier of CE approved gloves (e.g. KCL International +49 66
59870, fax +49 6659 87155).
Eye
for additional information : see : Annex.
The usual precautions for handling chemicals should be observed.
Skin and body
for additional information : see : Annex.
The usual precautions for handling chemicals should be observed.

Dust (general)
Time Weighted Average (TWA) 8 mg/m³ total dust.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance
powder ( 25 °C )
Color
white
Odor
odorless
odor threshold: not determined

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DISSOLVINE NA2
Boiling point/range
not applicable
Melting point/freezing point
Decomposes prior to melting.
Flash point
not applicable
Flammability
no
Explosive properties
no
Oxidizing properties
no
Vapor pressure
not applicable
Density
not applicable
Bulk density
approx. 700 kg/m³
Solubility in water
approx. 100 g/l
Solubility in other solvents
not determined
pH value
4 - 5 (1 % solution )
Partition coefficient n-octanol/water
Log Pow < 0
Relative vapor density (air=1)
not applicable
Viscosity
not applicable
Autoignition temperature
>200 °C (glowing temperatur of 5 mm product layer)
Upper/lower flammability or explosive limits
Lower Explosion Limit >= 40 g/m³
Decomposition temperature
not determined

10. STABILITY AND REACTIVITY

Conditions to avoid
Reaction with strong oxidizing agents. Product layer on hot surface might cause glowing or autoignition.
Chemical stability
Stable under recommended storage and handling conditions (see section 7)
Incompatible materials
none known.
Hazardous decomposition products
Emits toxic fumes under fire conditions (nitrous gases (NOx))

11. TOXICOLOGICAL INFORMATION

Ethylenediaminetetraacetic acid, disodium salt
Acute toxicity

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Material safety data sheet

DISSOLVINE NA2
Oral LD50
2800 mg/kg (No guideline followed )
Dermal LD50
No data available
Inhalation LC50
1000< 4-h-LC50 < 5000 mg/m³ (similar to : OECD 403)
Summary of toxicological information
The substance is a solid and not acutely toxic via the oral route. It is harmful following acute inhalation
exposure. It is not irritating to skin and eyes. It is not a dermal sensitiser. In repeated long-term oral studies with
EDTA compounds the overall NOAEL was about 500 mg/kg bw. The substance is not genotoxic or
carcinogenic, Based on studies with other EDTA compounds, the substance is not classified for reproduction
toxicity.
Germ cell mutagenicity
Based on available data, the classification criteria are not met .
STOT - single exposure
Conclusive but not sufficient for classification .
STOT - repeated exposure
Conclusive but not sufficient for classification .
Aspiration hazards
Not likely to occur (solid)
Irritation
Skin
Non-irritating (OECD 404)
Eye
Non-irritating (similar to : OECD 405)
Respiratory
Non-irritating (Based on: acute inhalation test ) (OECD 403)
Sensitization
Not sensitizing (OECD 406)
Genotoxicity
Based on "read-across" (Hydroxyethylethylenediaminetriacetic acid, trisodium salt):
Ames test: Negative (OECD 471).
Chromosome Aberration Test : Negative (OECD 473).
Mouse Lymphoma test : Negative (OECD476).
In vivo micronucleus test: Negative (OECD 474).
Chronic toxicity / Carcinogenicity
oral:
90-day No Observed Adverse Effect Level (NOAEL): 500 mg/kg (general signs of toxicity ; No guideline
followed )

Based on "read-across" (Hydroxyethylethylenediaminetriacetic acid, trisodium salt):

104 week No Observed Adverse Effect Level (NOAEL) >= 500 mg/kg (No guideline followed ).

inhalation:
5-day Lowest observable adverse effect concentration (LOAEC) : 30 mg/m³ (respiratory tract pathology) (OECD
412).

Diethylenetriaminepentaacetic acid, pentasodium salt

Based on "read-across" (Ethylenediaminetetraacetic acid, calcium-disodium complex):
oral, NOAEL reproduction : >= 250 mg/kg (No guideline followed ).

Based on "read-across" (several EDTA compounds ): developmental effects seen at high oral doses only .
NOAEL development : was not established (No guideline followed ).

Neurotoxicity test: No specific information available .

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Material safety data sheet

DISSOLVINE NA2
Other toxicological information
Chronic toxicity (Dermal): No data available

12. ECOLOGICAL INFORMATION

Ethylenediaminetetraacetic acid, disodium salt
Ecotoxicity
Ecotoxicological information

Ethylenediaminetetraacetic acid, disodium salt: not dangerous to the environment .

PBT or vPvB : no.

fish
Based on "read-across" (several EDTA compounds ):
Lepomis macrochirus, 96-h-LC50 > 1000 mg/l (No guideline followed )

Based on "read-across" (Ethylenediaminetetraacetic acid, calcium-disodium complex):

Brachydanio rerio, 35-day No Observed Effect Concentration (NOEC) >= 25.7 mg/l (OECD 210)
daphnia
Daphnia magna, 48-h-EC50: 140 mg/l (DIN 38412, 11)

Daphnia magna, 21-day No Observed Effect Concentration (NOEC): 25 mg/l (Guideline : EEC XI/681/86, Draft
: 4)
algae
Based on "read-across" (Ethylenediaminetetraacetic acid, ferric-sodium complex): Desmodesmus subspicatus
and Pseudokirchnerella subcapitata, 72-h-EC50 > 300 mg/l (OECD 201)
bacteria
30-min. EC20 > 500 mg/l (OECD 209)
Fate
Degradation Abiotic
photodegradable; Half-life: 20 days. expected to be: resistant to hydrolysis .
Degradation Biotic
EDTA (acid form) and its salts are not readily biodegradable. Under special conditions like adaptation or slightly
alkaline pH, which is realistic under environmental surface water conditions, the biodegradability of EDTA is
considerably enhanced and as such EDTA is considered ultimately biodegradable .
Bioaccumulation
Lepomis macrochirus, Flow-through, 28-day, 1< Bio Concentration Factor (BCF) <2 (No guideline followed )
Other information
No adsorption No adsorption expected onto soil due to ionic structure. The test substance will preferentially
distribute into the water compartment and not evaporate from the water surface .

13. DISPOSAL CONSIDERATIONS

Product
According to local regulations.
Contaminated packaging
No specific recommendations.

14. TRANSPORT INFORMATION

Land transport
Transport hazard class
not restricted
UN number
not relevant

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DISSOLVINE NA2
Proper Shipping Name
not relevant

Sea transport (IMO / IMDG-code)

Transport hazard class
not restricted
Packing group
none
UN number
none
EMS
not relevant
Marine pollutant
no
Proper Shipping Name
not relevant

Air transport (ICAO-TI / IATA-DGR)

UN number
none
Transport hazard class
not restricted
Packing group
none
Proper Shipping Name
not relevant

15. REGULATORY INFORMATION

Product label name
Ethylenediaminetetraacetic acid, disodium salt, dihydrate, approx. 100%

Hazard classes
Description Applicable
Chinese Inventory Listed on Chinese Existing Chemical Substances Inventory

R(isk) phrase(s) (EU classification)

Code Description
R20. Harmful by inhalation.

S(afety) phrase(s) (EU classification)

Code Description
S22. Do not breathe dust.

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Material safety data sheet

DISSOLVINE NA2
Classification according to 67/548/EC as ammended

G
HARMFUL (Xn)

Other information
Source of key data: IUCLID 5 datasheet:

16. OTHER INFORMATION

Relevant hazard statements

Chemical name Hazard
statement(s)
(GHS-classifcat
ion)

History
Date of printing/
pdf file generated
2011/11/14
Revision
1.00
Composed by
E. C. Rietveld
M. Heus
Changes were made in section
all
This information only concerns the above mentioned product and does not need to be valid if used with other product(s) or in any process. The information is to our best present
knowledge correct and complete and is given in good faith but without warranty. It remains the user's own responsibility to make sure that the information is appropriate and
complete for his special use of this product

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