ANNA UNIVERSITY, CHENNAI

NON-AUTONOMOUS COLLEGES AFFILIATED COLLEGES

REGULATIONS 2021
CHOICE BASED CREDIT SYSTEM

B. TECH. BIOTECHNOLOGY

1. Program Objectives (POs)

The primary objective of the Bachelor of Industrial Biotechnology program is to prepare
professionals with the skills required to work in the Biotechnology industry with particular emphasis
on the engineering aspects of manufacturing and design.
They are trained to
1. Achieve successful professional and technical career.
2. Have a strong foundation in Basic Sciences, Mathematics, Medical Sciences,
Bioinformatics and process engineering.
3. Have knowledge on the theory and practices in the field of Biotechnology, especially in the
areas of downstream processing, Medical biotechnology and Bioinformatics and allied
areas.
4. Engross in life-long learning to keep themselves abreast of new developments in
Biotechnology.
5. Practice and inspire high ethical values and technical standards.
The Overall objective of the Program is to promote education and research in biotechnology and
provide academic and professional excellence for immediate productivity in industrial,
governmental, or clinical settings for an ultimate benefit of society and environment.
As a result of this program, the student will be able to:
1. Recall factual information on broad knowledge based proficiency in core themes,
principles and components of Basic Sciences.
2. Create and develop strategies that reflect the interdisciplinary nature of science,
regulation and enterprise in the biotechnology industry.
3. Define and solve problems using scientific methods in biotechnology and allied
subjects.
4. Consider implications of biotechnology in societal, environmental and educational
frameworks.
5. Access current information and literature in science and Prepare and present scientific
data.
6. Demonstrate knowledge of biological processes from the molecular and cellular
perspectives.
7. Approach and solve biological problems critically with scientific literacy in individual and
group settings.
8. Able to understand, analyze and apply the process engineering concepts an incredibly
wide diversity of applications including pharmaceutical development, crop and livestock
improvement, diagnostic and therapeutic medicine, industrial processing, and
bioremediation of contaminated environments.
1
Program Specific Outcome:
PSO I:
Impart the deeper insights in to the Fundamentals of Biotechnology topics and to familiarize them
with various upcoming and challenging areas relevant to biotechnology sector.
PSO II:
Analyse and perform the experimental procedures to address the societal problems through
modern tools and techniques in biotechnology.
PSO III:
Apply the interdisciplinary knowledge acquired through the program to solve problems in the
biotechnology industry.
PSO IV:
Demonstrate the innovative research ideas and to provide cost-effective and sustainable solutions
in Biotechnology.

Programme Programme Outcomes Programme specific

Objective Outcomes
1 2 3 4 5 6 7 8 I II III IV
I ✔ ✔ ✔
II ✔ ✔ ✔ ✔ ✔
III ✔ ✔ ✔ ✔
IV ✔ ✔ ✔ ✔ ✔ ✔
V ✔ ✔ ✔ ✔

2
 Mapping for B. Tech. Biotechnology – R2021
PSO
PO
I II III IV
1 2 3 4 5 6 7 8
Professional English - I ✔ ✔
1 Matrices and Calculus ✔ ✔
Engineering Physics ✔ ✔
S
E Engineering Chemistry ✔ ✔
Y M Problem Solving and Python ✔
✔ ✔
e Programming
a Problem Solving and Python ✔
✔
r Programming Laboratory
Physics and Chemistry
1 Laboratory ✔

Professional English - II ✔
Statistics and Numerical ✔
2 Methods ✔ ✔
Engineering Graphics ✔ ✔
S
Materials Science for ✔
E ✔ ✔ ✔
Biotechnologists
M
Basic Electrical, Electronics ✔
and Instrumentation ✔
Engineering
Bioorganic Chemistry ✔ ✔ ✔
Engineering Practices ✔
✔
Laboratory
Bioorganic Chemistry ✔
Laboratory ✔ ✔

Transforms and Partial ✔

✔ ✔
3Differential Equations
Biochemical ✔
S Thermodynamics ✔ ✔ ✔
E Cell Biology ✔ ✔ ✔
M Chemical Process ✔
✔
Calculations
Microbiology ✔ ✔ ✔
Biochemistry ✔ ✔ ✔
Y Biochemistry Laboratory ✔ ✔
e Cell Biology and ✔
a Microbiology Laboratory ✔ ✔ ✔
r
Probability and Statistics ✔ ✔ ✔ ✔
2
Fluid Flow and Heat ✔
4 ✔ ✔
Transfer Operations
S
Industrial Enzymology ✔ ✔ ✔
E Basic Industrial ✔
✔
M Biotechnology
Analytical Techniques In ✔
✔ ✔
Biotechnology

3
 Environmental Science and ✔
✔ ✔ ✔
Sustainability
Chemical Engineering ✔
Laboratory for ✔ ✔
Biotechnologists
Analytical Instrumentation ✔ ✔
Laboratory ✔

Protein Engineering ✔ ✔ ✔ ✔
Bioprocess Principles ✔ ✔ ✔
Molecular Biology and ✔
5 Genetics ✔ ✔
Professional Elective I ✔
S
E Professional Elective II ✔
M
Professional Elective III ✔
Y
e Bioinformatics Laboratory ✔
Molecular Biology ✔ ✔ ✔ ✔
a Laboratory
r Genetic Engineering and ✔
✔ ✔ ✔
genomics
Bioprocess Engineering ✔ ✔ ✔ ✔
3 6
Professional Elective IV ✔
S Professional Elective V ✔
E
M Professional Elective VI ✔
Open Elective – I ✔ ✔
Bioprocess Laboratory ✔ ✔ ✔
Genetic Engineering ✔
✔ ✔ ✔
Laboratory
Life Skills and Soft Skills ✔ ✔ ✔
7 Elective- Management ✔ ✔ ✔

Y
Downstream Processing ✔ ✔ ✔
e S Immunology ✔ ✔
a E Open Elective – II ✔
r M Open Elective – III ✔
Open Elective – IV ✔
4
Downstream Processing ✔
✔ ✔ ✔
Laboratory
Immunology Laboratory ✔ ✔ ✔ ✔
✔ ✔

Project Work ✔ ✔ ✔
S
E
M

4
 ANNA UNIVERSITY, CHENNAI
NON-AUTONOMOUS COLLEGES AFFILIATED COLLEGES
REGULATIONS 2021
B. TECH. BIOTECHNOLOGY
CHOICE BASED CREDIT SYSTEM
CURRICULUM FOR SEMESTERS I TO VIII AND SYLLABI FOR SEMESTERS III AND IV
SEMESTER I
PERIODS PER TOTAL CREDITS
S. COURSE CATE-
COURSE TITLE WEEK CONTACT
No. CODE GORY
L T P PERIODS
1. IP3151 Induction Programme - - - - - 0
THEORY
2. HS3151 Professional English - I HSMC 3 0 0 3 3
3. MA3151 Matrices and Calculus BSC 3 1 0 4 4
4. PH3151 Engineering Physics BSC 3 0 0 3 3
5. CY3151 Engineering Chemistry BSC 3 0 0 3 3
Problem Solving and Python
6. GE3151 ESC 3 0 0 3 3
Programming
7. GE3172 அ யல் த ழ் / HSMC 1 0 0 1 1
Scientific Thoughts in Tamil
PRACTICALS
Problem Solving and Python
8. GE3171 ESC 0 0 4 4 2
Programming Laboratory
Physics and Chemistry
9. BS3171 BSC 0 0 4 4 2
Laboratory
10. GE3172 English Laboratory $ EEC 0 0 2 2 1
TOTAL 16 1 10 27 22

$ Skill Based Course

5
 SEMESTER II

PERIODS TOTAL
S. COURSE CATE- PERWEEK
COURSE TITLE CONTACT CREDITS
No. CODE GORY
L T P PERIODS
THEORY
1. HS3251 Professional English - II HSMC 2 0 0 2 2
2. Statistics and Numerical BSC
MA3251 3 1 0 4 4
Methods
3. Materials Science for PCC
PH3252 3 0 0 3 3
Biotechnologists
4. Basic Electrical, Electronics ESC
BE3252 and Instrumentation 3 0 0 3 3
Engineering
5. GE3251 Engineering Graphics ESC 2 0 4 6 4
6. BT3201 Bioorganic Chemistry PCC 3 0 0 3 3
7. GE3252 த ழர் மர / Heritage of
HSMC 1 0 0 1 1
Tamils
8. NCC Credit Course Level 1* - 2 0 0 2 2
PRACTICALS
9. GE3271 Engineering Practices ESC
0 0 4 4 2
Laboratory
10. BT3211 Bioorganic Chemistry
PCC 0 0 4 4 2
Laboratory
11. Communication Laboratory /
GE3272 EEC 0 0 4 4 2
Foreign Language $
TOTAL 17 1 16 36 26
#NCC Credit Course level 1 is offered for NCC students only. The grades earned by the students will be
recorded in the Mark Sheet, however the same shall not be considered for the computation of CGPA.
$ Skill Based Course

SEMESTER III
PERIODS
PER TOTAL
S. COURSE CATE
COURSE TITLE WEEK CONTACT CREDITS
NO. CODE GORY
PERIODS
L T P
THEORY
1. MA3351 Transforms and Partial
BSC 3 1 0 4 4
Differential Equations
2. BT3392 Biochemistry PCC 3 0 0 3 3
3. BT3351 Cell Biology PCC 3 0 0 3 3
4. BT3352 Microbiology PCC 3 0 0 3 3
5. BT3301 Biochemical PCC
3 0 0 3 3
Thermodynamics
6. BT3391 Basic Industrial
PCC 3 0 0 3 3
Biotechnology
PRACTICALS
7. BT3361 Biochemistry Laboratory PCC 0 0 3 3 1.5
8. BT3311 Cell and Microbiology PCC
0 0 3 3 1.5
Laboratory
9. GE33361 Professional Development$ EEC 0 0 2 2 1
TOTAL 18 1 8 27 23
$ Skill Based Course
6
 SEMESTER IV
PERIODS
PER TOTAL
S. COURSE CATE
COURSE TITLE WEEK CONTACT CREDITS
NO. CODE GORY
PERIODS
L T P
THEORY
1. BT3401 Molecular Biology PCC 3 0 0 3 3
2. GE3451 Environmental Sciences
BSC 2 0 0 2 2
and Sustainability
3. BT3402 Fluid Flow and Heat ESC
3 0 0 3 3
Transfer Operations
4. BT3451 Analytical Techniques In
PCC 3 0 0 3 3
Biotechnology
5. BT3491 Chemical Process
Calculations in PCC 3 0 0 3 3
Biotechnologist
6. BT3452 Industrial Enzymology PCC 3 0 0 3 3
7. NCC Credit Course Level 2# 3 0 0 3 3
PRACTICALS
8. BT3411 Chemical Engineering PCC
Laboratory for 0 0 3 3 1.5
Biotechnologists
9. BT3461 Analytical Instrumentation PCC
0 0 3 3 1.5
Laboratory
10. BT3512 Industrial EEC
- - - - -
Training/Internship I*
TOTAL 17 0 6 23 20

# NCC Credit Course level 2 is offered for NCC students only. The grades earned by the students will be
recorded in the Mark Sheet, however the same shall not be considered for the computation of CGPA.
*Four weeks industrial training/internship carries two credits. Industrial training/internship during IV Semester Summer
Vacation will be evaluated in V semester
SEMESTER V

PERIODS TOTAL
S. COURSE CATE PER WEEK
COURSE TITLE CONTACT CREDITS
NO. CODE GORY
L T P PERIODS
THEORY
1. BT3551 Bioprocess Principles PCC 3 0 0 3 3
2. BT3552 Immunology PCC 3 0 0 3 3
3. BT3501 Genetic Engineering PCC 3 0 0 3 3
4. Professional Elective I PEC 3 0 0 3 3
5. Professional Elective II PEC 3 0 0 3 3
6. Professional Elective III PEC 3 0 0 3 3
7. Mandatory Course-I& MC 3 0 0 3 0
PRACTICALS
8. BT3511 Molecular Biology & Genetic PCC
0 0 4 4 2
Engineering laboratory
9. BT3561 Immunology Laboratory PCC 0 0 3 3 1.5
10. BT3512 Industrial Training/Internship EEC
- - - - 2
I**
TOTAL 18 0 7 25 23.5
7
 &
Mandatory Course-I is a Non-credit Course (Student shall select one course from the list given under MC-I)
**Four weeks industrial training/internship carries two credits. Industrial training/internship during IV Semester Summer
Vacation will be evaluated in V semester
SEMESTER VI
PERIODS TOTAL
S. COURSE CATE PER WEEK
COURSE TITLE CONTACT CREDITS
NO. CODE GORY
L T P PERIODS
THEORY
1. BT3601 Bioinformatics PCC 3 0 0 3 3
2. BT3651 Bioprocess Engineering PCC 3 0 0 3 3
3. Professional Elective IV PEC 3 0 0 3 3
4. Professional Elective V PEC 3 0 0 3 3
5. Open Elective – I* OEC 3 0 0 3 3
6. Mandatory Course--II& MC 3 0 0 3 0
7. NCC Credit Course Level
3 0 0 3 3
3#
PRACTICALS
8. BT3611 Bioinformatics Lab PCC 0 0 3 3 1.5
9. BT3661 Bioprocess Laboratory PCC 0 0 3 3 1.5
10. BT3711 Industrial EEC
- - - - -
Training/Internship II**
TOTAL 18 0 6 24 18
*Open Elective – I shall be chosen from the emerging technologies.
**Two weeks industrial training/internship carries one credit. Industrial training/Internship during VI Semester Summer
Vacation will be evaluated in VII semester
&
Mandatory Course-II is a Non-credit Course (Student shall select one course from the list given under MC- II)
#
NCC Credit Course level 3 is offered for NCC students only. The grades earned by the students will be
recorded in the Mark Sheet, however the same shall not be considered for the computation of CGPA.

SEMESTER VII/VIII*
PERIODS TOTAL
S. COURSE CATE PER WEEK
COURSE TITLE CONTACT CREDITS
NO. CODE GORY
L T P PERIODS
THEORY
1. BT3751 Downstream Processing PCC 3 0 0 3 3
2. GE3791 Human values and Ethics HSMC 2 0 0 2 2
3. Management Elective# HSMC 3 0 0 3 3
4. Professional Elective VI PEC 3 0 0 3 3
5. Open Elective – II** OEC 3 0 0 3 3
6. Open Elective – III*** OEC 3 0 0 3 3
7. Open Elective – IV*** OEC 3 0 0 3 3
PRACTICALS
8. BT3761 Downstream Laboratory PCC 0 0 3 3 1.5
9. BT3711 Industrial EEC
- - - - 2
Training/Internship II##
TOTAL 20 0 3 23 23.5
*If students undergo internship in Semester VII, then the courses offered during semester VII will be offered
during semester VIII.
**Open Elective – II shall be chosen from the emerging technologies.
***Open Elective III and IV (Shall be chosen from the list of open electives offered by other Programmes
#
Elective- Management shall be chosen from the Elective Management courses
##
Two weeks industrial training/internship carries one credit. Industrial training/Internship during VI Semester Summer
Vacation will be evaluated in VII semester
8
 SEMESTER VIII/VII*

PERIODS TOTAL
S. COURSE CATE PER WEEK
COURSE TITLE CONTACT CREDITS
NO. CODE GORY
L T P PERIODS
PRACTICALS
1. BT3811 Internship#/ Project Work EEC 0 0 20 20 10
TOTAL 0 0 20 20 10
*If students undergo internship in Semester VII, then the courses offered during semester VII will be offered
during semester VIII.
#
15 weeks of continuous Internship in an organization carries 10 credits.
TOTAL CREDITS: 166
ELECTIVE – MANAGEMENT COURSES

COURSE PERIODS TOTAL

SL. CATE PERWEEK
CODE COURSE TITLE CONTACT CREDITS
NO. GORY
L T P PERIODS
1. GE3751 Principles of Management HSMC 3 0 0 3 3
2. GE3752 Total Quality Management HSMC 3 0 0 3 3
3. GE3753 Engineering Economics and HSMC 3 0 0 3 3
Financial Accounting
4. GE3754 Human Resource HSMC 3 0 0 3 3
Management
5. GE3755 Knowledge Management HSMC 3 0 0 3 3
6. GE3792 Industrial Management HSMC 3 0 0 3 3

MANDATORY COURSES I
SL. COURSE PERIODS TOTAL
CATE PER WEEK
NO CODE COURSE TITLE CONTACT CREDITS
GORY
. L T P PERIODS
1. MX3081 Introduction to Women and MC 3 0 0 3 0
Gender Studies
2. MX3082 Elements of Literature MC 3 0 0 3 0
3. MX3083 Film Appreciation MC 3 0 0 3 0
4. MX3084 Disaster Management MC 3 0 0 3 0

9
 MANDATORY COURSES II
COURSE PERIODS TOTAL
SL. CATE PER WEEK
CODE COURSE TITLE CONTACT CREDITS
NO. GORY
L T P PERIODS
1. MX3085 Well Being with traditional MC 3 0 0 3 0
practices (Yoga, Ayurveda
and Siddha)
2. MX3086 History of Science and MC 3 0 0 3 0
Technology in India
3. MX3087 Political and Economic MC 3 0 0 3 0
Thought for a Humane
Society
4. MX3088 State, Nation Building and MC 3 0 0 3 0
Politics in India
5. MX3089 Industrial Safety MC 3 0 0 3 0

10
 PROFESSIONAL ELECTIVE COURSES : VERTICALS

Vertical IV
Vertical I Vertical II Vertical III Vertical V Vertical VI Vertical VII Vertical VIII
Bio Chemical Quality and Agro
Bioprocess Medical Animal Computational
Biosciences Engineering Regulatory Biotechnolog
Technology Biotechnology Biotechnology Biotechnology
Affairs y
Human Genetics Mass Transfer Fundamentals of Programming for Clinical Trials and Plant anatomy
Bioprocess Control Operations Animal Bioinformatics Health care
Biosensors Biotechnology policies in
and Instrumentation Applications
Biotechnology
Cancer Biology Transport Animal Health and Fundamentals of Biotechnological Therapeutic
Fermentation
Bio- Phenomena in Nutrition Algorithms for products and its application of
Technology
Nanotechnology Biological Bioinformatics validation phytochemical
(Shifted from
System (Shifted s
Vertical IV to
from Vertical I to
Vertical I )
Vertical IV )
Biopharmaceutica Bioenergy and Animal Physiology Molecular Modelling Quality assurance Bio-fertilizer
Food Processing Stem Cell ls and Biosimilars Biofuels and Metabolism and quality control production &
and Technology Technology in Biotechnology mushroom
cultivation
Tissue Environmental Animal Cell Culture Computer Aided Entrepreneurship Biotechnologic
Bioreactor Design Biomaterials Engineering Biotechnology Technology Drug Design and patent design al approach in
and Scale up crop
process improvement

Protein Engineering Molecular Applied Advances in Animal Metabolomics and Intellectual Advance
Bioprocess
Therapeutics and Chemical Biotechnology Metabolic property rights in techniques in
Modelling and
Diagnostics Reaction Engineering Biotechnology agro forestry
Simulation
Engineering
(Newly added)
Modern Bio Biomedical Petroleum Biotechniques in Data Mining And Biosafety and Plant tissue
Bioreactor analytical Animal Breeding Machine Learning Hazard culture &
Engineering Biotechnology
Consideration for Techniques Techniques For Management transformation
Recombinant Bioinformatics techniques
Products

11
Registration of Professional Elective Courses from Verticals:
Professional Elective Courses will be registered in Semesters V and VI. These courses are listed in groups
called verticals that represent a particular area of specialisation. Students are permitted to choose all
Professional Electives from a particular vertical or from different verticals. Further, only one Professional
Elective course shall be chosen in a semester horizontally (row-wise). However, two courses are permitted
from the same row, provided one course is enrolled in Semester V and another in semester VI.
The registration of courses for B.E./B.Tech (Honours) or Minor degree shall be done from Semester V to
VIII. The procedure for registration of courses explained above shall be followed for the courses of
B.E/B.Tech (Honours) or Minor degree also. For more details on B.E./B.Tech (Honours) or Minor degree
refer to Regulations 2021 Clause 4.10.
.

PROFESSIONAL ELECTIVE COURSES : VERTICALS

VERTICAL I: BIOPROCESS TECHNOLOGY

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3001 Bioprocess Control PEC 3 0 0 3 3
and Instrumentation
2. BT3002 Fermentation PEC 3 0 0 3 3
Technology
3. BT3003 Food Processing and PEC 3 0 0 3 3
Technology
4. BT3004 Bioreactor Design PEC 3 0 0 3 3
and Scale up
process
5. CBT331 Bioprocess Modelling PEC 3 0 0 3 3
and Simulation
6. BT3005 Bioreactor PEC 3 0 0 3 3
Consideration for
Recombinant
Products

VERTICAL II: BIOSCIENCES

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3006 Biosensors PEC 3 0 0 3 3
2. BT3007 Bio-Nanotechnology PEC 3 0 0 3 3

3. BT3008 Stem Cell PEC 3 0 0 3 3

Technology
4. BT3009 Biomaterials PEC 3 0 0 3 3

5. BT3010 Protein Engineering PEC 3 0 0 3 3

6. BT3011 Modern Bio analytical PEC 3 0 0 3 3

Techniques

12
 VERTICAL III: MEDICAL BIOTECHNOLOGY

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3012 Human Genetics PEC 3 0 0 3 3
2. CBT372 Cancer Biology PEC 3 0 0 3 3

3. BT3013 Biopharmaceuticals PEC 3 0 0 3 3

and Biosimilars
4. CBT333 Tissue Engineering PEC 3 0 0 3 3

5. BT3014 Molecular PEC 3 0 0 3 3

Therapeutics and
Diagnostics
6. BT3015 Biomedical PEC 3 0 0 3 3
Engineering

VERTICAL IV: BIO CHEMICAL ENGINEERING

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3016 Mass Transfer PEC 3 0 0 3 3
Operations
2. BT3017 Transport PEC 3 0 0 3 3
Phenomena in
Biological System
3. BT3018 Bioenergy and PEC 3 0 0 3 3
Biofuels
4. BT3019 Environmental PEC 3 0 0 3 3
Biotechnology
5. BT3020 Applied Chemical PEC 3 0 0 3 3
Reaction Engineering
6. BT3021 Petroleum PEC 3 0 0 3 3
Biotechnology

13
 VERTICAL V: ANIMAL BIOTECHNOLOGY

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3022 Fundamentals of PEC 3 0 0 3 3
Animal Biotechnology
2. BT3023 Animal Health and PEC 3 0 0 3 3
Nutrition
3. BT3024 Animal Physiology and PEC 3 0 0 3 3
Metabolism
4. BT3025 Animal Cell Culture PEC 3 0 0 3 3
Technology
5. BT3026 Advances in Animal PEC 3 0 0 3 3
Biotechnology
6. BT3027 Biotechniques in PEC 3 0 0 3 3
Animal Breeding

VERTICAL VI: COMPUTATIONAL BIOTECHNOLOGY

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3028 Programming for PEC 3 0 0 3 3
Bioinformatics
Applications
2. BT3029 Fundamentals of PEC 3 0 0 3 3
Algorithms for
Bioinformatics
3. BT3030 Molecular Modelling PEC 2 1 0 3 3
4. CPY331 Computer Aided PEC 3 0 0 3 3
Drug Design
5. BT3031 Metabolomics and PEC 3 0 0 3 3
Metabolic
Engineering
6. BT3032 Data Mining And PEC 3 0 0 3 3
Machine Learning
Techniques For
Bioinformatics

14
 VERTICAL VII: QUALITY AND REGULATORY AFFAIRS

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3033 Clinical Trials and PEC 3 0 0 3 3
Health care policies in
Biotechnology
2. BT3034 Biotechnological PEC 3 0 0 3 3
products and its
validation
3. BT3035 Quality assurance and PEC 3 0 0 3 3
quality control in
Biotechnology
4. BT3036 Entrepreneurship and PEC 3 0 0 3 3
patent design
5. BT3037 Intellectual property PEC 3 0 0 3 3
rights in Biotechnology
6. BT3038 Biosafety and Hazard PEC 3 0 0 3 3
Management

VERTICAL VIII: AGRO BIOTECHNOLOGY

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. BT3039 Plant anatomy PEC 3 0 0 3 3
2. BT3040 Therapeutic PEC 3 0 0 3 3
application of
phytochemicals
3. BT3041 Bio-fertilizer PEC 3 0 0 3 3
production &
mushroom cultivation
4. BT3042 Biotechnological PEC 3 0 0 3 3
approach in crop
improvement
5. BT3043 Advance techniques in PEC 3 0 0 3 3
agro forestry
6. BT3044 Plant tissue culture & PEC 3 0 0 3 3
transformation
techniques

15
 OPEN ELECTIVES
Students shall choose the open elective courses, such that the course contents are not similar to
any other course contents/title under other course categories.

OPEN ELECTIVE I AND II

(EMERGING TECHNOLOGIES)
To be offered other than Faculty of Information and Communication Engineering
COURSE PERIODS TOTAL
SL. CATE
CODE COURSE TITLE PER WEEK CONTACT CREDITS
NO. GORY
L T P PERIODS
1. OCS351 Artificial Intelligence and OEC 2 0 2 4 3
Machine Learning
Fundamentals
2. OCS352 IoT Concepts and OEC 2 0 2 4 3
Applications
3. OCS353 Data Science Fundamentals OEC 2 0 2 4 3
4. OCS354 Augmented and Virtual OEC 2 0 2 4 3
Reality

OPEN ELECTIVES – III

COURSE PERIODS TOTAL

SL. CATE PER WEEK
CODE COURSE TITLE CONTACT CREDITS
NO. GORY
L T P PERIODS
1. OHS351 English for OEC 3 0 0 3 3
Competitive
Examinations
2. OCE353 Lean Concepts, Tools OEC 3 0 0 3 3
And Practices
3. OMG352 NGOs and OEC 3 0 0 3 3
Sustainable
Development
4. OMG353 Democracy and Good OEC 3 0 0 3 3
Governance
5. OME353 Renewable Energy OEC 3 0 0 3 3
Technologies
6. OME354 Applied Design OEC 2 0 2 4 3
Thinking
7. OMF351 Reverse Engineering OEC 3 0 0 3 3
8. OMF353 Sustainable OEC 3 0 0 3 3
Manufacturing
9. OAU351 Electric and Hybrid OEC 3 0 0 3 3
Vehicle
10. OAS352 Space Engineering OEC 3 0 0 3 3
11. OIM351 Industrial Management OEC 3 0 0 3 3
12. OIE354 Quality Engineering OEC 3 0 0 3 3
13. OSF351 Fire Safety OEC 3 0 0 3 3

16
 Engineering
14. OML351 Introduction to non- OEC 3 0 0 3 3
destructive testing
15. OMR351 Mechatronics OEC 3 0 0 3 3
16. ORA351 Foundation of OEC 3 0 0 3 3
Robotics
17. OAE352 Fundamentals of OEC 3 0 0 3 3
Aeronautical
engineering
18. OGI351 Remote Sensing OEC 3 0 0 3 3
Concepts
19. OAI351 Urban Agriculture OEC 3 0 0 3 3
20. OEN351 Drinking Water Supply OEC 3 0 0 3 3
and Treatment
21. OEE352 Electric Vehicle OEC 3 0 0 3 3
technology
22. OEI353 Introduction to PLC OEC 3 0 0 3 3
Programming
23. OCH351 Nano Technology OEC 3 0 0 3 3
24. OCH352 Functional Materials OEC 3 0 0 3 3
25. OPY352 IPR for Pharma OEC 3 0 0 3 3
Industry
26. OTT351 Basics of Textile OEC 3 0 0 3 3
Finishing
27. OTT352 Industrial Engineering OEC 3 0 0 3 3
for Garment Industry
28. OTT353 Basics of Textile OEC 3 0 0 3 3
Manufacture
29. OPE351 Introduction to OEC 3 0 0 3 3
Petroleum Refining
and Petrochemicals
30. OPE352 Energy Conservation OEC 3 0 0 3 3
and Management
31. OPT351 Basics of Plastics OEC 3 0 0 3 3
Processing
32. OEC351 Signals and Systems OEC 3 0 0 3 3
33. OEC352 Fundamentals of OEC 3 0 0 3 3
Electronic Devices and
Circuits
34. OBM351 Foundation Skills in OEC 3 0 0 3 3
integrated product
Development
35. OBM352 Assistive Technology OEC 3 0 0 3 3
36. OMA352 Operations Research OEC 3 0 0 3 3
37. OMA353 Algebra and Number OEC 3 0 0 3 3
Theory
38. OMA354 Linear Algebra OEC 3 0 0 3 3

17
 OPEN ELECTIVES – IV

COURSE PERIODS TOTAL

SL. CATE PER WEEK
CODE COURSE TITLE CONTACT CREDITS
NO. GORY
L T P PERIODS
1. OHS352 Project Report Writing OEC 3 0 0 3 3
2. OCE354 Basics of Integrated OEC 3 0 0 3 3
Water Resources
Management
3. OMA355 Advanced Numerical OEC 3 0 0 3 3
Methods
4. OMA356 Random Processes OEC 3 0 0 3 3
5. OMA357 Queuing and OEC 3 0 0 3 3
Reliability Modelling
6. OMG354 Production and OEC 3 0 0 3 3
Operations
Management for
Entrepreneurs
7. OMG355 Multivariate Data OEC 3 0 0 3 3
Analysis
8. OME352 Additive Manufacturing OEC 3 0 0 3 3
9. OME353 New Product OEC 3 0 0 3 3
Development
10. OME355 Industrial Design & OEC 2 0 2 4 3
Rapid Prototyping
Techniques
11. OMF352 Micro and Precision OEC 3 0 0 3 3
Engineering
12. OMF354 Cost Management of OEC 3 0 0 3 3
Engineering Projects
13. OAU352 Batteries and OEC 3 0 0 3 3
Management system
14. OAU353 Sensors and Actuators OEC 3 0 0 3 3
15. OAS353 Space Vehicles OEC 3 0 0 3 3
16. OIM352 Management Science OEC 3 0 0 3 3
17. OIM353 Production Planning OEC 3 0 0 3 3
and Control
18. OIE353 Operations OEC 3 0 0 3 3
Management
19. OSF352 Industrial Hygiene OEC 3 0 0 3 3
20. OSF353 Chemical Process OEC 3 0 0 3 3
Safety
21. OML352 Electrical, Electronic OEC 3 0 0 3 3
and Magnetic
materials
22. OML353 Nanomaterials and OEC 3 0 0 3 3
applications
23. OMR353 Sensors OEC 3 0 0 3 3
24. ORA352 Foundation of OEC 3 0 0 3 3
Automation
25. ORA353 Concepts in Mobile OEC 3 0 0 3 3
18
 Robotics
26. OMV351 Marine Propulsion OEC 3 0 0 3 3
27. OMV352 Marine Merchant OEC 3 0 0 3 3
Vehicles
28. OMV353 Elements of Marine OEC 3 0 0 3 3
Engineering
29. OAE353 Drone Technologies OEC 3 0 0 3 3
30. OGI352 Geographical OEC 3 0 0 3 3
Information System
31. OAI352 Agriculture OEC 3 0 0 3 3
Entrepreneurship
Development
32. OEE353 Introduction to control OEC 3 0 0 3 3
systems
33. OCH353 Energy Technology OEC 3 0 0 3 3
34. OCH354 Surface Science OEC 3 0 0 3 3
35. OEI354 Introduction to OEC 3 0 0 3 3
Industrial Automation
Systems
36. OTT354 Basics of Dyeing and OEC 3 0 0 3 3
Printing
37. OTT355 Fibre Science OEC 3 0 0 3 3
38. OTT356 Garment OEC 3 0 0 3 3
Manufacturing
Technology
39. OPE353 Industrial safety OEC 3 0 0 3 3
40. OPE354 Unit Operations in OEC 3 0 0 3 3
Petro Chemical
Industries
41. OPT352 Plastic Materials for OEC 3 0 0 3 3
Engineers
42. OPT353 Properties and Testing OEC 3 0 0 3 3
of Plastics
43. OEC353 VLSI Design OEC 3 0 0 3 3
44. OEC354 Industrial IoT and OEC 2 0 2 4 3
Industry 4.0
45. OBM353 Wearable devices OEC 3 0 0 3 3
46. OBM354 Medical Informatics OEC 3 0 0 3 3

19
 SUMMARY

Name of the Programme

Subject
Credits per Semester Total
S.No Area
Credits
I II III IV V VI VII/VIII VIII/VII
1 HSMC 4 3 5 12
2 BSC 12 4 4 2 22
3 ESC 5 9 3 17
4 PCC 8 18 15 12.5 9 4.5 67
5 PEC 9 6 3 18
6 OEC 3 9 12
7 EEC 1 2 1 2 2 10 18

Non-Credit
8 √ √
/(Mandatory)

Total 22 26 23 20 23.5 18 23.5 10 166

20
 Enrollment for B.E. / B. Tech. (Honours) / Minor degree (Optional)
A student can also optionally register for additional courses (18 credits) and become eligible for
the award of B.E./B.Tech. (Honours) Minor degree.
For B.E. / B. Tech. (Honours), a student shall register for the additional courses (18 credits) from
semester V onwards. These courses shall be from the same vertical or a combination of different
verticals of the same programme of study only.
For minor degree, a student shall register for the additional courses (18 credits) from semester V
onwards. All these courses have to be in a particular vertical from any one of the other
programmes, Moreover, for minor degree the student can register for courses from any one of the
following verticals also.
Complete details are available in clause 4.10 of Regulations 2021.
Verticals FOR MINOR DEGREE (IN ADDITIONS TO ALL THE VERTICALS OF OTHER
PROGRAMMES)
Vertical IV
Vertical I Vertical III Business Vertical V
Vertical II
Fintech and Public Data Environment and
Entrepreneurship
Block Chain Administration Analytics Sustainability

Financial Foundations of Principles of Statistics For Sustainable

Management Entrepreneruship Public Management infrastructure
Administration Development
Fundamentals Team Building & Constitution of Datamining Sustainable
of Investment Leadership India For Business Agriculture and
Management for Intelligence Environmental
Business Management
Banking, Creativity & Public Human Sustainable Bio
Financial Innovation in Personnel Resource Materials
Services and Entrepreneurship Administration Analytics
Insurance
Introduction to Principles of Administrative Marketing Materials for Energy
Blockchain Marketing Theories And Social Sustainability
and its Management For Media Web
Applications Business Analytics

Fintech Human Resource Indian Operation Green Technology

Personal Management for Administrative And Supply
Finance and Entrepreneurs System Chain
Payments Analytics

Introduction to Financing New Public Policy Financial Environmental

Fintech Business Ventures Administration Analytics Quality Monitoring
and Analysis
- - - - Integrated Energy
Planning for
Sustainable
Development
- - - - Energy Efficiency for
Sustainable
Development
21
(Choice of courses for Minor degree is to be made from any one vertical of other
programmes or from anyone of the following verticals)

VERTICAL 1: FINTECH AND BLOCK CHAIN

SL PERIODS
COURSE PER TOTAL
. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
N GORY
PERIODS
O. L T P
1. CMG331 Financial Management PEC 3 0 0 3 3
2. CMG332 Fundamentals of
PEC 3 0 0 3 3
Investment
3. CMG333 Banking, Financial
PEC 3 0 0 3 3
Services and Insurance
4. CMG334 Introduction to
Blockchain and its PEC 3 0 0 3 3
Applications
5. CMG335 Fintech Personal
PEC 3 0 0 3 3
Finance and Payments
6. CMG336 Introduction to Fintech PEC 3 0 0 3 3

VERTICAL 2: ENTREPRENEURSHIP

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. CMG337 Foundations of
PEC 3 0 0 3 3
Entrepreneruship
2. CMG338 Team Building &
Leadership
PEC 3 0 0 3 3
Management for
Business
3. CMG339 Creativity & Innovation
PEC 3 0 0 3 3
in Entrepreneurship
4. CMG340 Principles of Marketing
Management For PEC 3 0 0 3 3
Business
5. CMG341 Human Resource
Management for PEC 3 0 0 3 3
Entrepreneurs
6. CMG342 Financing New
PEC 3 0 0 3 3
Business Ventures

22
 VERTICAL 3: PUBLIC ADMINISTRATION

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. CMG343 Principles of Public
PEC 3 0 0 3 3
Administration
2. CMG344 Constitution of India PEC 3 0 0 3 3
3. CMG345 Public Personnel
PEC 3 0 0 3 3
Administration
4. CMG346 Administrative Theories PEC 3 0 0 3 3
5. CMG347 Indian Administrative
PEC 3 0 0 3 3
System
6. CMG348 Public Policy
PEC 3 0 0 3 3
Administration

VERTICAL 4: BUSINESS DATA ANALYTICS

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. CMG349 Statistics For
PEC 3 0 0 3 3
Management
2. CMG350 Datamining For Business PEC 3 0 0 3 3
Intelligence
3. CMG351 Human Resource
PEC 3 0 0 3 3
Analytics
4. CMG352 Marketing And Social
PEC 3 0 0 3 3
Media Web Analytics
5. CMG353 Operation And Supply
PEC 3 0 0 3 3
Chain Analytics
6. CMG354 Financial Analytics PEC 3 0 0 3 3

23
 VERTICAL 5: ENVIRONMENT AND SUSTAINABILITY

PERIODS
COURSE PER TOTAL
SL. CATE
CODE COURSE TITLE WEEK CONTACT CREDITS
NO. GORY
PERIODS
L T P
1. CES331 Sustainable infrastructure
PEC 3 0 0 3 3
Development
2. CES332 Sustainable Agriculture
and Environmental PEC 3 0 0 3 3
Management
3. CES333 Sustainable Bio Materials PEC 3 0 0 3 3
4. CES334 Materials for Energy
PEC 3 0 0 3 3
Sustainability
5. CES335 Green Technology PEC 3 0 0 3 3
6. CES336 Environmental Quality
PEC 3 0 0 3 3
Monitoring and Analysis
7. CES337 Integrated Energy
Planning for Sustainable PEC 3 0 0 3 3
Development
8. CES338 Energy Efficiency for
Sustainable PEC 3 0 0 3 3
Development

24
MA3351 TRANSFORMS AND PARTIAL DIFFERENTIAL EQUATIONS L T P C
3 1 0 4
OBJECTIVES
 To introduce the basic concepts of PDE for solving standard partial differential equations.
 To introduce Fourier series analysis which is central to many applications in engineering apart
from its use in solving boundary value problems.
 To acquaint the student with Fourier series techniques in solving heat flow problems used in
various situations.
 To acquaint the student with Fourier transform techniques used in wide variety of situations.
 To introduce the effective mathematical tools for the solutions of partial differential equations
that model several physical processes and to develop Z transform techniques for discrete
time systems.

UNIT I PARTIAL DIFFERENTIAL EQUATIONS 9+3

Formation of partial differential equations –Solutions of standard types of first order partial
differential equations - First order partial differential equations reducible to standard types-
Lagrange’s linear equation - Linear partial differential equations of second and higher order with
constant coefficients of both homogeneous and non-homogeneous types.

UNIT II FOURIER SERIES 9+3

Dirichlet’s conditions – General Fourier series – Odd and even functions – Half range sine series
and cosine series – Root mean square value – Parseval’s identity – Harmonic analysis.

UNIT III APPLICATIONS OF PARTIAL DIFFERENTIAL EQUATIONS 9+3

Classification of PDE – Method of separation of variables - Fourier series solutions of one
dimensional wave equation – One dimensional equation of heat conduction – Steady state
solution of two dimensional equation of heat conduction (Cartesian coordinates only).

UNIT IV FOURIER TRANSFORMS 9+3

Statement of Fourier integral theorem– Fourier transform pair – Fourier sine and
cosine transforms – Properties – Transforms of simple functions – Convolution theorem –
Parseval’s identity.

UNIT V Z - TRANSFORMS AND DIFFERENCE EQUATIONS 9+3

Z-transforms - Elementary properties – Convergence of Z-transforms - – Initial and final value
theorems - Inverse Z-transform using partial fraction and convolution theorem - Formation of
difference equations – Solution of difference equations using Z - transforms.
TOTAL: 60 PERIODS
OUTCOMES
Upon successful completion of the course, students should be able to:
 Understand how to solve the given standard partial differential equations.
 Solve differential equations using Fourier series analysis which plays a vital role in
engineering applications.
 Appreciate the physical significance of Fourier series techniques in solving one and two
dimensional heat flow problems and one dimensional wave equations.
 Understand the mathematical principles on transforms and partial differential equations
would provide them the ability to formulate and solve some of the physical problems of
engineering.
 Use the effective mathematical tools for the solutions of partial differential equations by
using Z transform techniques for discrete time systems.

25
TEXT BOOKS:
1. Grewal B.S., “Higher Engineering Mathematics", 44thEdition, Khanna Publishers,
New Delhi, 2018.
2. Kreyszig E, "Advanced Engineering Mathematics ", 10th Edition, John Wiley, New Delhi, India,
2016.

REFERENCES:
1. Andrews. L.C and Shivamoggi. B, "Integral Transforms for Engineers" SPIE Press, 1999.
2. Bali. N.P and Manish Goyal, "A Textbook of Engineering Mathematics", 10th Edition, Laxmi
Publications Pvt. Ltd, 2015.
3. James. G., "Advanced Modern Engineering Mathematics", 4thEdition, Pearson Education,
New Delhi, 2016.
4. Narayanan. S., Manicavachagom Pillay.T.K and Ramanaiah.G "Advanced Mathematics for
Engineering Students", Vol. II & III, S.Viswanathan Publishers Pvt. Ltd, Chennai, 1998.
5. Ramana. B.V., "Higher Engineering Mathematics", McGraw Hill Education Pvt. Ltd,
New Delhi, 2018.
6. Wylie. R.C. and Barrett . L.C., “Advanced Engineering Mathematics “Tata McGraw Hill
Education Pvt. Ltd, 6th Edition, New Delhi, 2012.

BT3392 BIOCHEMISTRY LTPC

3 0 03
OBJECTIVE
To enable students learn the fundamentals of Biochemical Processes and Biomolecules

UNIT I INTRODUCTION TO BIOMOLECULES - CARBOHYDRATES: 9

Basic principles of organic chemistry, role of carbon, types of functional groups, chemical,
nature of water, pH and biological buffers, bio molecules structure and properties of
Carbohydrates (mono, di, oligo & polysaccharides) Proteoglycans, glucosaminoglycans.
mutarotation, glycosidic bond, reactions of monosaccharides, reducing sugars. Starch,
glycogen, cellulose and chitin. Proteoglycans, glycosaminoglycans. hyaluronic acid,
chondroitin sulfate

UNIT II STRUCTURE AND PROPERTIES OF OTHER BIOMOLECULES 9

Structure and properties of Important Biomolecules.
Lipids: fatty acids, glycerol, saponification, iodination, hydrogenation, phospholipids,
glycolipids, sphingolipids, cholesterol, steroids, prostaglandins.
Protein: Amino Acids, Peptides, Proteins, measurement, structures, hierarchy of organization
primary, secondary, tertiary and quaternary structures, glycoproteins, lipoproteins. Determine
of primary structure.
Nucleic acids: purines, pyrimidines, nucleoside, nucleotide, RNA, DNA-Watson-Crick
structure of DNA, reactions, properties, measurement, nucleoprotein complexes

UNIT III METABOLISM CONCEPTS AND CARBOHYDRATE METABOLISM 9

Functions of Proteins, Enzymes, introduction to biocatalysts, metabolic pathways, primary and
secondary metabolites. Interconnection of pathways and metabolic regulation. Glycolysis,
TCA cycle, gluconeogenesis, pentose phosphate shunt & glyoxalate shunt.

UNIT IV INTERMEDIARY METABOLISM AND REGULATION 9

Fatty acid synthesis and oxidation, reactions of amino acids, deamination, transamination and

26
decarboxylation, urea cycle, Bioenergetics - High energy compounds, electronegative
potential of compounds, respiratory chain, ATP cycle, calculation of ATP yield during oxidation
of glucose and fatty acids.
UNIT V PROTEIN TRANSPORT AND DEGRADATION 9
Protein targeting, signal sequence, secretion; Folding, Chaperone and targeting of organelle
proteins, Protein degradation, receptor-mediated endocytosis, turnover.
TOTAL: 45 PERIODS
OUTCOMES
 To ensure students have a strong foundation in the structure and reactions of Biomolecules.
 To introduce them to metabolic pathways of the major biomolecules and relevance to clinical
conditions.
 To correlate Biochemical processes with Biotechnology applications.

TEXT BOOKS
1. Lehninger Principles of Biochemistry 6th Edition by David L. Nelson, Michael M. Cox
W.H.Freeman and Company 2017
2. Satyanarayana, U. and U. Chakerapani, “Biochemistry” 3rd Rev. Edition, Books & Allied
(P) Ltd., 2006.
3. Rastogi, S.C. “Biochemistry” 2nd Edition, Tata McGraw-Hill, 2003.
4. Conn, E.E., etal., “Outlines of Biochemistry” 5th Edition, John Wiley & Sons, 1987.
5. Outlines of Biochemistry, 5th Edition: By E E Conn, P K Stumpf, G Bruening and R Y Doi. pp
693. John Wiley and Sons, New York. 1987.

REFERENCES
1. Berg, Jeremy M. et al. “Biochemsitry”, 6th Edition, W.H. Freeman & Co., 2006.
2. Murray, R.K., etal “Harper’s Illustrated Biochemistry”, 31st Edition, McGraw-Hill, 2018.
3. Voet, D. and Voet, J.G., “Biochemistry”, 4th Edition, John Wiley & Sons Inc.,2010.

BT3351 CELL BIOLOGY LTPC

3 003
OBJECTIVES:
 To provide knowledge on the fundamentals of cell biology
 To help students understand the signalling mechanisms

UNIT I CELL STRUCTURE AND FUNCTION OF THE ORGANELLES 9

Prokaryotic, Eukaryotic cells, Sub-cellular organelles and functions. Principles of membrane
organization membrane proteins, cytoskeletal proteins. Extra cellular matrix, cell-cell junctions.

UNIT II CELL DIVISION, CANCER, APOPTOSIS AND IMMORTALIZATION OF CELLS 9

Cell cycle – Mitosis, Meiosis, Molecules controlling cell cycle, cancer, role of Ras and Raf in
oncogenesis and apoptosis. Stem cells, Cell culture and immortalization of cells and its
applications.

UNIT III TRANSPORT ACROSS CELL MEMBRANE 9

Passive and Active Transport, Permeases, Ion channels, ATP pumps. Na+ / K+ /Ca+2Tpumps,
uniport, symport antiporter system. Ligand gated / voltage gated channels, Agonists and
Antagonists.
27
UNIT IV SIGNAL TRANSDUCTION 9
Receptors – extracellular signaling, Cell surface / cytosolic receptors and examples,
Differentclasses of receptors antocrine / paracrine / endocrine models, Secondary messengers
molecules.

UNIT V TECHNIQUES USED TO STUDY CELLS 9

Cell fractionation and flow cytometry, Morphology and identification of cells using microscopic
studies like SEM, TEM and Confocal Microscopy. Localization of proteins in cells –
Immunostaining.
TOTAL: 45 PERIODS
OUTCOMES:
Upon completion of this course, the students
 Would have deeper understanding of cell at structural and functional level.
 Would have broad knowledge on the molecular interaction between cells.
 Would demonstrate a clear understanding of the signal transduction, secondary
 messengers.
 Would develop skill on working principles of microscopy and identification of cell types.

TEXT BOOKS:
1. Lodish, Harvey etal., “Molecular Cell Biology”, 7th Edition, W.H.Freeman, 2013.
2. Cooper, G.M. and R.E. Hansman “The Cell: A Molecular Approach”, 8th Edition, Oxford
University Press, 2018.
3. Alberts, Bruce etal., “Molecular Biology of the Cell”, 6th Edition, W.W. Norton,2014
4. Sadava, D.E. “Cell Biology: Organelle Structure and Function”, Panima Publishing, 2004.
5. Rastogi, S.C. “Cell Biology” 2nd Edition, New Age International, 2017

REFERENCES:
1. Becker, W.M. etal., “The World of the Cell”, 9th Edition, Pearson Education, 2003.
2. Campbell, N.A., J.B. Recee and E.J. Simon “Essential Biology”, VIIrd Edition, Pearson
International, 2007.
3. Alberts, Bruce etal., “Essential Cell Biology”, 4th Edition, W.W. Norton, 2013

BT3352 MICROBIOLOGY LTPC

3 003
OBJECTIVES
 To introduce students to the principles of Microbiology to emphasize structure and
biochemical aspects of various microbes.
 To solve the problems in microbial infection and their control.

UNIT I : INTRODUCTION
Basics of microbial existence; history of microbiology, classification and nomenclature of 9
microorganisms, microscopic examination of microorganisms, light and electron
microscopy; principles of different staining techniques like gram staining, acid fast,
capsular staining, flagellar staining.

UNIT II: MICROBES- STRUCTURE AND MULTIPLICATION 9

Structural organization and multiplication of bacteria, viruses, algae and fungi, with
special mention of life history of actinomycetes, yeast, mycoplasma and bacteriophages.

UNIT III : MICROBIAL NUTRITION, GROWTH AND METABOLISM 9

Nutritional requirements of bacteria; different media used for bacterial culture; growth
28
curve and different methods to quantify bacterial growth; aerobic and anaerobic
bioenergetics and utilization of energy for biosynthesis of important molecules.

UNIT IV : CONTROL OF MICROORGANISMS 9

Physical and chemical control of microorganisms; host-microbe interactions; anti-
bacterial, anti-fungal and anti-viral agents; mode of action and resistance to antibiotics;
clinically important microorganisms.

UNIT V : INDUSTRIAL AND ENVIRONMENTAL MICROBIOLOGY 9

Primary metabolites; secondary metabolites and their applications; preservation of
food;production of penicillin, alcohol, vitamin B-12; biogas; bioremediation; leaching of
ores by microorganisms; biofertilizers and biopesticides; microorganisms and pollution
control; biosensors
TOTAL: 45 PERIODS
TEXT BOOKS
1. Pelczar MJ, Chan ECS and Krein NR, Microbiology, Tata McGraw Hill Edition, New
Delhi, India,2009
2. Prescott L.M., Harley J.P., Klein DA, Microbiology, 3rd Edition, Wm. C. Brown Publishers,
1996.

REFERENCE BOOKS
1. Black, Text book of microbiology. Freeman Publishers,2016
2. Talaron K, Talaron A, Casita, Pelczar and Reid. Foundations in Microbiology, W.C. Brown
Publishers, 1993.
3. Ananthanarayan, CK Jayaram Panikars. Text book of Microbiology, 2005, Orient
Blackswan Publishers.

BT3301 BIOCHEMICAL THERMODYNAMICS L T PC

3 0 03
OBJECTIVE:
 To enable the students to learn about basic concepts of classical and statistical
thermodynamics

UNIT I THERMODYNAMIC LAW AND PROPERTIES OF FLUIDS

First Law of thermodynamics, a generalized balance equation and conserved quantities, 9
Volumetric properties of fluids exhibiting non ideal behavior; residual properties; estimation of
thermodynamic properties using equations of state; calculations involving actual property
exchanges; Maxwell’s relations and applications.

UNIT II SOLUTION THERMODYNAMICS 9

Partial molar properties; concepts of chemical potential and fugacity; ideal and non-ideal
solutions; concepts and applications of excess properties of mixtures; activity coefficient;
composition models; Gibbs Duhem equation.

UNIT III PHASE EQUILIBRIA 9

Criteria for phase equilibria; VLE calculations for binary and multi component systems; liquid-
liquid equilibria and solid-solid equilibria.

29
UNIT IV CHEMICAL REACTION EQUILIBRIA 9
Equilibrium criteria for homogeneous chemical reactions; evaluation of equilibrium constant;
effect of temperature and pressure on equilibrium constant; calculation of equilibrium
conversion and yields for single and multiple reactions.

UNIT V : THERMODYNAMIC DESCRIPTION OF MICROBIAL GROWTH AND PRODUCT 9

FORMATION
Thermodynamics of microbial growth stoichiometry thermodynamics of maintenance,
Calculation of the Operational Stoichiometry of a growth process at Different growth rates,
Including Heat using the Herbert –Pirt Relation for Electron Donor, thermodynamics and
stoichiometry of Product Formation
TOTAL: 45 PERIODS
OUTCOMES:
At the end of this course, the student would have the ability
 To explain the theoretical concepts of thermodynamics and how it applies to energy conversion
in technological applications and biological systems.
 To demonstrate the capability to analyze the energy conversion performance in avariety of
modern applications in biological systems.
 To design and carry out bioprocess engineering experiments, and analyze and interpret
fundamental data to do the design and operation of bioprocesses.
 To describe the criteria when two phases coexist in equilibrium and the vapour liquid
equilibrium calculations microbial growth and product formation.

TEXT BOOKS:
1. Smith J.M., Van Ness H.C., and Abbot M.M. “Introduction to Chemical Engineering
Thermodynamics”, VIth Edition. Tata McGraw-Hill, 2003.
2. Narayanan K.V. “A Text Book of Chemical Engineering Thermodynamics”, PHI, 2003.
3. Christiana D. Smolke, “ The Metabolic Pathway Engineering Handbook Fundamentals”, CRC
Press Taylor & Francis Group, 2010.

REFERENCE:
Sandler S.I. “Chemical and Engineering Thermodynamics”, John Wiley,1989.

BT3391 BASIC INDUSTRIAL BIOTECHNOLOGY LTPC

3 003
OBJECTIVES:
 To make the students aware of the overall industrial bioprocess so as to help them to
manipulate the process to the requirement of the industrial needs.
 The course prepares the students for the bulk production of commercially important modern
Bioproducts, Industrial Enzymes, Products of plant and animal cell cultures

UNIT I INTRODUCTION TO INDUSTRIAL BIOPROCESS

Fermentation- Bacterial, Fungal and Yeast, Biochemistry of fermentation. Traditional and 9
Modern Biotechnology- A brief survey of organisms, processes, products. Basic concepts of
Upstream and Downstream processing in Bioprocess, Process flow sheeting – block diagrams,
pictorial representation.

UNIT II PRODUCTION OF PRIMARY METABOLITES 9

Primary Metabolites- Production of commercially important primary metabolites like organic
acids, amino acids and alcohols.
30
UNIT III PRODUCTION OF SECONDARY METABOLITES 9
Secondary Metabolites- Production processes for various classes of secondary metabolites:
Antibiotics, Vitamins and Steroids.

UNIT IV PRODUCTION OF ENZYMES AND OTHER BIOPRODUCTS 9

Production of Industrial Enzymes, Biopesticides, Biofertilizers, Biopreservatives, Biopolymers
Biodiesel. Cheese, Beer, SCP & Mushroom culture, Bioremediation.

UNIT V PRODUCTION MODERN BIOTECHNOLOGY PRODUCTS 9

Production of recombinant proteins having therapeutic and diagnostic applications, vaccines.
Bioprocess strategies in Plant Cell and Animal Cell culture.
TOTAL: 45 PERIODS
OUTCOMES:
At the end of the course, the students will be able
 To explain the steps involved in the production of bioproducts and methods to improve modern
biotechnology.
 To apply basic biotechnological principles, methods and models to solve biotechnological
tasks.
 To identify and debate the ethical, legal, professional, and social issues in the field of
biotechnology.
 To design and deliver useful modern biotechnology products to the Society..

TEXT BOOKS:
1. Satyanarayana, U. “Biotechnology” Books & Allied (P) Ltd., 2005.
2. Kumar, H.D. “A Textbook on Biotechnology” IInd Edition. Affiliated East West Press Pvt.Ltd.,
1998.
3. Balasubramanian, D. etal., “Concepts in Biotechnology” Universities Press Pvt. Ltd., 2004.
4. Ratledge, Colin and Bjorn Kristiansen “Basic Biotechnology” IInd Edition Cambridge University
Press, 2001.
5. Dubey, R.C. “A Textbook of Biotechnology” S.Chand & Co. Ltd., 2006.

REFERENCES:
1. Casida, L.E. “Industrial Microbiology”, New Age International (P) Ltd, 1968.
2. Presscott, S.C. and Cecil G. Dunn, “Industrial Microbiology”, Agrobios (India), 2005.
3. Cruger,Wulf and Anneliese Crueger, “Biotechnology: A Textbook of Industrial Microbiology”,IInd
Edition, Panima Publishing, 2000.
4. Moo-Young, Murrey, “Comprehensive Biotechnology”, 4 Vols. Pergamon Press, (An Imprintof
Elsevier) 2004.
5. Stanbury, P.F., A. Whitaker and S.J. Hall “Principles of Fermentation Technology”, IInd
Edition, Butterworth – Heinemann (an imprint of Elsevier), 1995.
6. C.F.A Bryce and EL.Mansi, Fermentation microbiology & Biotechnology, 1999.
7. K.G.Ramawat & Shaily Goyal, Comprehensive Biotechnology, 2009, S.Chand publications.

31
BT3361 BIOCHEMISTRY LABORATORY LTPC
0 0 3 1.5
AIM
 To learn and understand the principles behind the qualitative and quantitative estimation of
biomolecules (proteins, carbohydrates, lipids, metabolites etc.,) and laboratory analysis of the
same in the body fluids.

EXPERIMENTS
1. General guidelines for working in biochemistry lab (theory)
2. Units of volume, weight, density and concentration measurements and their range in
biological measurements. Demonstration of proper use of volume and weight measurement
devices.
3. Accuracy, precision, sensitivity and specificity (theory)
4. Preparation of buffer –titration of a weak acid and a weak base.
5. Qualitative tests for carbohydrates – distinguishing reducing from non-reducing sugars
and keto from aldo sugars.
6. Quantitative method for amino acid estimation using ninhydrin – distinguishing amino
from imino acid.
7. Protein estimation by Biuret and Lowry’s methods.
8. Protein estimation by Bradford and spectroscopic methods.
9. Extraction of lipids and analysis by TLC.
10. Estimation of nucleic acids by absorbance at 260 nm and hyperchromic effect (demo).
11. Enzymatic assay: phosphatase from potato.
12. Enzymatic assay: estimation of glucose by GOD-POD method after hydrolysis of starch
with acid and specificity of the enzymatic method.

Equipment Needed for 20 Students

Autocalve 1
Hot Air Oven 1
Incubators 2
Light Microscopes 4
Incubator Shaker 1
Colorimeter 2
Laminar Flow Chamber 2
Glassware:
Test tubes (atleast 10 per student)
Beakers – 50 ml, 100 ml, 250 ml one each per student, 500 ml and 1000 ml atleast 5 per batch
of 20 students
Watch glasses one per student
Petridishes as required, glass cuvettes as needed
Burette – one per student
Glass pipette – one each in 0.5 ml, 1 ml, 5 ml and 10 ml with suitable pipette aid.
TLC plate as required for the experiment.

Chemicals: glucose, fructose, galactose, maltose, starch, amino acids, DNA, RNA, lipids and
commercial enzymes as required. Other chemicals as per the requirement of the standard
protocol and commercial kit procured from the vendor followed/ utilised by the deparment
TOTAL: 45 PERIODS
TEXT BOOKS
1. Practical Biochemistry by R.C. Gupta and S. Bhargavan.
2. Introduction of Practical Biochemistry by David T. Phummer. (II Edition)

32
REFERENCES
1. Harpers Biochemistry Ed. R.K. Murray , D.K. Granner, P.A. Mayes and V.W.Rodwell,
Appleton and Lange ,Stanford ,Conneticut.
2. Textbook of Biochemistry with clinical correlations. Ed. Thomas M. Devlin. Wiley Liss
Publishers

BT3311 CELL AND MICROBIOLOGY LABORATORY L T P C

0 0 3 1.5
AIM
 To demonstrate various techniques to learn the morphology, identification and propagation of
cells and microbes

EXPERIMENTS
1. Introduction, Laboratory Safety, Use of Equipment; Sterilization Techniques
2. Microscopy – Working and care of Microscope, phase contrast and fluorescent microscopy
3. Culture Media-Types and Use; Preparation of Nutrient broth and agar
4. Culture Techniques, Isolation and Preservation of Cultures- Broth: flask, test tubes;
Solid:Pour plates, streak plates, slants, stabs
5. Identification of given plant, animal, bacterial cells and yeast/mould
6. Staining Techniques Simple, Differential- Gram’s Staining, spore /capsule staining, Giemsa,
and Leishman Staining
7. Quantification of Microbes: Sampling and Serial Dilution; Bacterial count in Soil – TVC
8. Effect of Disinfectants- Phenol Coefficient, Antibiotic Sensitivity Assay
9. Osmosis and Tonicity and Tryphan Blue Assay
10. Growth Curve in Bacteria and Yeast
11. Staining for different stages of mitosis in AlliumCepa (Onion)
12. Effect of pH, Temperature, UV radiation on Growth Bacteria

Equipment Needed for 20 Students

Autoclave 1
Hot Air Oven 1
Incubators 2
Light Microscopes 4
Incubator Shaker 1
Colorimeter 2
Lamina Flow Chamber 2
Glassware: Petridish, Test tubes,Microscopic slides, Inoculation , loop, Gas burner

Chemicals and media

Bacterial culture media, Yeast culture media, 70% ethanol ,antibiotics, Crystal violet, Iodine,
Safranin, India ink (capsule staining), Immersion oil

TOTAL: 45 PERIODS
OUTCOMES:
Students will be able to
33
  Understand the advanced technical information pertaining to laboratory bio-safety and
preventive measures from pathogenic microorganism.
 Know the various aseptic techniques and sterilization methods.
 Develop the minimum skills to work on several important techniques for the study of
microorganisms in the laboratory.
 To identify the various stages of mitosis

REFERENCES:
1. Cappuccino, J.G. and N. Sherman “Microbiology: A Laboratory Manual”, 4th Edition,
Addison-Wesley, 1999.
1. Collee, J.G. etal., “Mackie & McCartney Practical Medical Microbiology” 4th Edition,
ChurchillLivingstone, 1996Rickwood, D. and J.R. Harris “Cell Biology: Essential
Techniques”, Johnwiley, 1996.
2. Davis, J.M. “Basic Cell Culture: A Practical Approach”, IRL, 1994.

BT3401 MOLECULAR BIOLOGY LTPC

3003
OBJECTIVES:
The course aims to
 Understand basic principles of molecular biology such as role of nucleic acids and proteins and
how these molecules interact at intracellular level to regulate growth, division and
development.
 Apply/relate such principles to manipulate the organisms appropriately for valuable outcome in
the area of science and technology.

UNIT I CHEMISTRY OF NUCLEIC ACIDS 9

Introduction to nucleic acids: Nucleic acids as genetic material, Structure and physicochemical
properties of elements in DNA and RNA, Biological significance of differences in DNA and
RNA. Primary structure of DNA: Chemical and structural qualities of 3’,5’-Phosphodiester
bond. Secondary Structure of DNA: Watson & Crick model, Chargaff’s rule, X–ray diffraction
analysis of DNA, Forces stabilizes DNA structure, Conformational variants of double helical
DNA, Hogsteen base pairing, Triple helix, Quadruple helix, Reversible denaturation and
hyperchromic effect. Tertiary structure of DNA: DNA supercoiling.

UNIT II DNA REPLICATION & REPAIR 9

Overview of Central dogma. Organization of prokaryotic and eukaryotic chromosomes. DNA
replication: Meselson & Stahl experiment, bi–directional DNA replication, Okazaki fragments,
Proteomics of DNA replication, Fidelity of DNA replication, Inhibitors of DNA replication,
Overview of differences in prokaryotic and eukaryotic DNA replication, Telomere replication in
eukaryotes. D-loop and rolling circle mode of replication. Mutagens, DNA mutations and their
mechanism, various types of repair mechanisms.
9
UNIT III TRANSCRIPTION
Structure and function of mRNA, rRNA and tRNA. Characteristics of promoter and enhancer
sequences. RNA synthesis: Initiation, elongation and termination of RNA synthesis, Proteins of
RNA synthesis, Fidelity of RNA synthesis, Inhibitors of transcription, Differences in prokaryotic
and eukaryotic transcription. Basic concepts in RNA world: Ribozymes, RNA processing: 5’-
Capping, Splicing-Alternative splicing, Poly ‘A’ tail addition and base modification.
34
 9
UNIT IV TRANSLATION
Introduction to Genetic code: Elucidation of genetic code, Codon degeneracy, Wobble
hypothesis and its importance, Prokaryotic and eukaryotic ribosomes. Steps in translation:
Initiation, Elongation and termination of protein synthesis. Inhibitors of protein synthesis.
Posttranslational modifications and its importance. Regulation of gene expression: lac- and
trp-operon.
9
UNIT V CELL DIVISION & CELL CYCLE
Cell division: Mitosis, Meiosis and Cytokinesis. Cell cycle: Methods in cell cycle analysis.
Regulation of cell cycle – Cell cycle check points, molecules and mechanisms of cell cycle
regulation. Cell cycle modulators.
.
TOTAL: 45 PERIODS
OUTCOMES:
At the end of the course the students will be able to
understand the composition, structure and characteristics of nucleic acids
understand the central dogma of life and its significance
comprehend the basic mechanisms of cell division and its status under proliferative and degenerative
disorders

TEXTBOOKS:
1. Friefelder, David. “Molecular Biology.” Narosa Publications, 1999
2. Weaver, Robert F. “Molecular Biology” IInd Edition, Tata McGraw-Hill, 2003.
3. Karp, Gerald “Cell and Molecular Biology : Concepts and Experiments” IVth Edition, John Wiley, 2005.
4. Friefelder, David and George M. Malacinski “Essentials of Molecular Biology” IInd Edition,
Panima Publishing, 1993.

REFERENCES
1. Cooper GM, Hausman RE. The Cell: A Molecular approach. 7th Edition, 2015.
2. Krebs JE, Goldstein ES, Kilpatrick ST. Lewin’s Essential GENES XII,12 th edition 2017
3. Nelson DL, Cox MM. Lehninger Principles of Biochemistry. 6th Edition, 2012.
4. Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of
the cell, 6th Edition, 2014.
5. Lodish H, Berk A, MatsudairaP,Kaiser CA, Krieger M, Schot MP, Zipursky L, Darnell J. Molecular Cell
Biology, 6th Edition, 2007.
6. Tropp, Burton E. “ Molecular Biology : Genes to Proteins”. IIIrd Edition. Jones and Bartlett, 2008.
7. Glick , B.R. and J.J. Pasternak. “Molecular Biotechnology : Principles and Applications of
Recombinant DNA” 4th Edition. ASM, 2010.

GE3451 ENVIRONMENTAL SCIENCES AND SUSTAINABILITY L T P C

2 0 0 2

UNIT I ENVIRONMENT AND BIODIVERSITY 6

Definition, scope and importance of environment – need for public awareness. Eco-system and
Energy flow– ecological succession. Types of biodiversity: genetic, species and ecosystem
diversity– values of biodiversity, India as a mega-diversity nation – hot-spots of biodiversity –
threats to biodiversity: habitat loss, poaching of wildlife, man-wildlife conflicts – endangered and
endemic species of India – conservation of biodiversity: In-situ and ex-situ.

35
UNIT II ENVIRONMENTAL POLLUTION 6
Causes, Effects and Preventive measures of Water, Soil, Air and Noise Pollutions.
Solid, Hazardous and E-Waste management. Case studies on Occupational Health and Safety
Management system (OHASMS). Environmental protection, Environmental protection acts .

UNIT III RENEWABLE SOURCES OF ENERGY . 6

Energy management and conservation, New Energy Sources: Need of new sources. Different
types new energy sources. Applications of- Hydrogen energy, Ocean energy resources, Tidal
energy conversion. Concept, origin and power plants of geothermal energy.

UNIT IV SUSTAINABILITY AND MANAGEMENT 6

Development , GDP ,Sustainability- concept, needs and challenges-economic, social and aspects
of sustainability-from unsustainability to sustainability-millennium development goals, and
protocols-Sustainable Development Goals-targets, indicators and intervention areas Climate
change- Global, Regional and local environmental issues and possible solutions-case studies.
Concept of Carbon Credit, Carbon Footprint. Environmental management in industry-A case study.

UNIT V SUSTAINABILITY PRACTICES 6

Zero waste and R concept, Circular economy, ISO 14000 Series, Material Life cycle assessment,
Environmental Impact Assessment. Sustainable habitat: Green buildings, Green materials, Energy
efficiency, Sustainable transports. Sustainable energy: Non-conventional Sources, Energy
Cycles-carbon cycle, emission and sequestration, Green Engineering: Sustainable urbanization-
Socio-economical and technological change.
TOTAL: 30 PERIODS
TEXT BOOKS:
1. Anubha Kaushik and C. P. Kaushik’s “Perspectives in Environmental Studies”, 6th Edition,
New Age International Publishers ,2018.
2. Benny Joseph, ‘Environmental Science and Engineering’, Tata McGraw-Hill, New Delhi,
2016.
3. Gilbert M.Masters, ‘Introduction to Environmental Engineering and Science’, 2nd edition,
Pearson Education, 2004.
4. Allen, D. T. and Shonnard, D. R., Sustainability Engineering: Concepts, Design and Case
Studies,1st Edition, Pearson, 2011.
5. Bradley. A.S; Adebayo, A.O., Maria, P. Engineering applications in sustainable design and
development, Cengage learning.
6. Environment Impact Assessment Guidelines, Notification of Government of India, 2006.
7. Mackenthun, K.M., Basic Concepts in Environmental Management, Lewis Publication,
London, 1998.

REFERENCE BOOKS :
1. R.K. Trivedi, ‘Handbook of Environmental Laws, Rules, Guidelines, Compliances and
Standards’, Vol. I and II, Enviro Media. 38 .
2. Cunningham, W.P. Cooper, T.H. Gorhani, ‘Environmental Encyclopedia’, Jaico Publ.,
House, Mumbai, 2001.
3. Dharmendra S. Sengar, ‘Environmental law’, Prentice hall of India PVT. LTD, New Delhi,
2007.
4. Rajagopalan, R, ‘Environmental Studies-From Crisis to Cure’, Oxford University Press,
2005.
5. Erach Bharucha “Textbook of Environmental Studies for Undergraduate Courses” Orient
Blackswan Pvt. Ltd. 2013.

36
BT3402 FLUID FLOW AND HEAT TRANSFER OPERATIONS LTPC
3003
OBJECTIVES:
 To introduce the students to the mechanics of fluids through a thorough understanding of the
properties of the fluids, behaviour of fluids under static conditions. The dynamics of fluids is
introduced through the control volume approach which gives an integrated understanding of
the transport of mass, momentum and energy.
 To expose to the applications of the conservation laws to a) flow measurements b) flow
through pipes (both laminar and turbulent) and c) forces on vanes.

UNIT I FLUID PROPERTIES & FLUID MECHANICS

Fluid definition- compressible, in compressible fluids – coefficient of isothermal compressibility,
Density, specific gravity, specific weight, surface tension, vapour pressure, viscosity.
Newtonian and Non-newtonian fluids. Fluid statics – Barometric equation – application for
incompressible and compressible fluids. Pressure changes in atmospheric air – Gauge and
absolute pressure – pressure measurement with Bourdon gauge & manometers. Centre of
pressure concept. Fluid Dynamics – equation of continuity – Bernoulli’s equation – press loss
in straight pipes – in fittings – expansion and contraction losses (applied to Newtonian Fluids
only) Fluid flow measurement, Orifice, venture & Rotameter for Newtonian fluids

UNIT II FLOW OF FLUID THROUGH PACKINGS

Fluidization, Fluid transport Industrial application of fluid flow through packing-characterics of
packed bed-Bed surface area-void fraction-Laminar flow through packed bed and turbulent
flow-pressure drop experienced by the fluid-equations and application problems. Fluidization
phenomena-Industrial application - minimum fluidization velocities. Industrial pipes and
fittings- Fluid moving machinery-pumps centrifugal, Reciprocating-gear, Peristaltic pumps,
Introduction togas moving machinery-Fans, blowers, compressors.

UNIT III CONDUCTION HEAT TRANSFER

Heat transfer phenomena-thermodynamics & heat transfer. Heat conduction – Fourier’s
equation –steady state conduction in plexor and radial systems – Resistance concept – series
and resistance in conduction –and parallel resistance in conduction – unsteady state
conduction – lumped capacity model – extended surfaces (Feris) –combined conduction &
convection – 2 dimensional conduction.

UNIT IV CONVECTION HEAT TRANSFER

Forced and natural convection – Dimensional analysis, Dimensional numbers, Convection heat
transfer coefficient, Correlations for flow over plate, through tubes, over spheres and cylinders,
Agitated systems, Packed columns, condensation phenomena, Film and drop wise
condensation over tubes. Billing phenomena, heat transfer coefficient.

UNIT V RADIATION HEAT TRANSFER AND HEAT TRANSFER EQUIPMENTS

Electromagnetic waves, energy of radiation, Planck’s equation-Blackbody, Radiation
exchange. Kirchhoff’s law, Stefen Boltemann equation of radiant energy – Wien’s law,
Radiation exchange between surfaces – black, gray bodies, view factors-sample problems.
Concept of overall heat transfer coefficient, Heat exchangers, types, boilers, Kettles, Heat
exchanger Design concept. NTU concept.
TOTAL: 45 PERIODS
OUTCOMES:
 The students will be able to get a basic knowledge of fluids in static, kinematic and dynamic
equilibrium.
 They will also gain the knowledge of the applicability of physical laws in addressing problems
in hydraulics.

37
TEXT BOOKS:
1. R.K. Bansal A Textbook of Fluid Mechanics, Laxmi Publications; Second edition, 2020
2. Heat & Mass Transfer by P. K. Nag, Tata McGraw Hill – IIIrd Edition 2003

REFERENCE:
1. K.A.Gavhane, Fluid flow Operations,Nirali publishers,1st Edition,2018
2. R.K.Rajput A text Book of Heat & Mass Transfer SI Units , S.Chand publisher,2018
3. Geankoplis. C.J ”Transport Process & separation Process Principles” IVth Edition Prentice Hall
of India 2013.

BT3451 ANALYTICAL TECHNIQUES IN BIOTECHNOLOGY LTPC

3 0 03
OBJECTIVES:
To enable the students
 To have a fundamental knowledge about the Light spectrum, Absoprtion, Fluorescence, NMR,
Mass spectroscopy
 To acquire knowledge on the different chromotographic methods for separation of biological
products.

UNIT I INTRODUCTION TO SPECTROMETRY

Properties of electromagnetic radiation- wave properties – components of optical instruments 9
– Sources of radiation – wavelength selectors – sample containers – radiation transducers –
Signal process and read outs – signal to noise ratio - sources of noise – Enhancement of
signal to noise - types of optical instruments – Principle of Fourier Transform optical
Measurements.

UNIT II MOLECULAR SPECTROSCOPY 9

Molecular absorption spectrometry – Measurement of Transmittance and Absorbance – Beer’s
law – Instrumentation - Applications -Theory of fluorescence and Phosphorescence –
Instrumentation – Applications – Theory of Infrared absorption spectrometry – IR
instrumentation – Applications – Theory of Raman spectroscopy – Instrumentation –
applications

UNIT III MAGNETIC RESONANCE SPECTROSCOPY AND MASS SPECTROMETRY 9

Theory of NMR – environmental effects on NMR spectra – chemical shift- NMR-spectrometers
– applications of 1H and 13C NMR- Molecular mass spectra – ion sources – Mass
spectrometer. Applications of molecular mass - Electron paramagnetic resonance- g values –
instrumentation.

UNIT IV SEPARATION METHODS 9

General description of chromatography – Band broadening and optimization of column
performance- Liquid chromatography – Partition chromatography – Adsorption
chromatography – Ion exchange chromatography -size exclusion chromatography- Affinity
chromatography- principles of GC and applications – HPLC- Capillary electrophoresis –
Applications.

38
UNIT V ELECTRO ANALYSIS AND SURFACE MICROSCOPY 9
Electrochemical cells- Electrode potential cell potentials – potentiometry- reference electrode –
ion selective and molecular selective electrodes – Instrument for potentiometric studies –
Voltametry – Cyclic and pulse voltametry- Applications of voltametry . Study of surfaces –
Scanning probe microscopes – AFM and STM.
TOTAL: 45 PERIODS
OUTCOME:
 On completion of the course, students will have a better understanding of spectroscopy andthe
separation techniques used for biological products.

TEXT BOOKS:
1. Skoog, D.A. F. James Holler, and Stanky, R.Crouch “Instrumental Methods of
Analysis”.CengageLearning , 2007.
2. Willard, Hobart, etal., “Instrumental Methods of Analysis”. VIIth Edition, CBS, 1986.
3. Fifield F.W., . Principles and Practice of Analytical Chemistry. Blackwell, Scientific
Publishers,2016

REFERENCES:
1. Sharma, B.K. “Instrumental Methods of Chemical Analysis: Analytical Chemistry”, Krishna
Prakashan Media (P) Ltd, 2014
2. Haven, Mary C., etal., “Laboratory Instrumentation “. 4th Edition, Wiley India Pvt Ltd, 2010
3. Philopose P.M.Analytical Biotechnology. Domihant Publishers & distributors, New Delhi,
2016.

BT3491 CHEMICAL PROCESS CALCULATIONSIN BIOTECHNOLOGIST L T PC

3 0 03
OBJECTIVE:
 To enable the students to learn about basic concepts of chemical process and
calculations
 The course aims to develop skills of the students in the area of Chemical Engineering
with emphasis in process calculations and fluid mechanics.
 This will enable the students to perform calculations pertaining to processes and
operations.

UNIT I BASIC CHEMICAL CALCULATIONS 9

Dimension – Systems of units esp. engineering FPS, Engineering MKS & SI systems –
Conversion from one system to the other – composition of mixtures and solutions – mass
fraction, mass %, mole fraction, mole %, mass ratios, molarity, molality, normality, ppm,
composition by density.

UNIT II IDEAL AND ACTUAL GAS EQUATIONS 9

Ideal and actual gas equations, Vander Walls, compressibility factor equations, Application to
pure gas & gas mixtures – partial pressures, partial volumes – Air-water vapour systems,
Humidity, Molar Humidity, Relative Humidity, % Saturation, humid Volume – Humidity chart –
wet, Dry bulb, Dew point temperatures, pH of solutions, Vapour pressure.

UNIT III MATERIAL BALANCE 9

Material balance concept – overall & component – material balance applications for
evaporator,

39
gas absorber without reaction, Distillation (Binary system), Liquid extraction, solid-liquid
extraction, drying, crystallization, Humidification, Reverse Osmosis separation and Mixing
Recycle and Bypass illustration

UNIT IV ENERGY BALANCE 9

General energy balance equation for open systems, closed system sensible heat calculation,
Heat required for phase change thermo chemistry, application of steam tables, Saturated and
superheated steam application in bioprocess

UNIT V CHEMICAL REACTION 9

Chemical Reaction-Limiting, excess component, Fractional conversion, Percent conversion, Fractional
yield in multiple reactions. Simple problems, Combustion Reactions.

TOTAL : 45 PERIODS
OUTCOMES:
Upon success completion of this course, the students will be able to:
 Solve problems related to units and conversions and fit the given data using the
methodologies
 Solve problems related to material and energy balance concepts & design reactors for
biochemical processes
 Apply their knowledge in the field of biochemical engineering from the principles of
Thermodynamics

TEXT BOOKS:
1. 1. Bhatt B.I & SB Thakore, Stoichiometry - Fifth edition Tata McGraw Hill 2017
2. K.A.Kavhane, Introduction to Process calculations,Nirali Publishers,1st Edition,2016
3. Himmelblau D.M “Basic principles & Calculations in Chemical Engineering” 8th edn PHI
2014.

REFERENCES:
1. McCabe W.L & J.C.Smiith & P.Harriot “Unit operations of chemical Engineering” 7thEdn
McGraw Hill 2017
2. S. Pushpavanam, Introduction to Chemical Engineering, PHI Learning Pvt. Ltd.,2012
3. Geankoplis C.J. “Transport process & Separation process Principles 4th edition-PHI 2006.

BT3452 INDUSTRIAL ENZYMOLOGY LTPC

3003
OBJECTIVES:
To enable the students
 To learn enzyme reactions and its characteristics along with the production and purification
process
 To give the student a basic knowledge concerning biotransformation reactions with the usage
of enzymes

UNIT I INTRODUCTION TO ENZYMES

Classification of enzymes. Mechanisms of enzyme action; concept of active site and energetics 9
of enzyme substrate complex formation; specificity of enzyme action; principles of catalysis –
collision theory, transition state theory; role of entropy in catalysis.

40
UNIT II KINETICS OF ENZYME ACTION 9
Kinetics of single substrate reactions; estimation of Michelis – Menten parameters,
multisubstrate reactions - mechanisms and kinetics; turnover number; types of inhibition &
models –substrate, product. Allosteric regulation of enzymes, Monod Changeux Wyman
model, pH and temperature effect on enzymes & deactivation kinetics.

UNIT III ENZYME IMMOBILIZATION AND BIOSENSORS 9

Physical and chemical techniques for enzyme immobilization – adsorption, matrix entrapment,
encapsulation, cross-linking, covalent binding etc., - examples, advantages and
disadvantages, design of enzyme electrodes and their application as biosensors in industry,
healthcare and environment.

UNIT IV PURIFICATION AND CHARACTERIZATION OF ENZYMES FROM NATURAL 9

SOURCES
Production and purification of crude enzyme extracts from plant, animal and microbial sources;
methods of characterization of enzymes; development of enzymatic assays

UNIT V BIOTRANSFORMATION APPLICATIONS OF ENZYMES 9

Hydrolytic- Ester bond, Amide, Epoxides, Nitriles, Reduction reactions –aldehydes, Ketones,
C=C, Oxidation reactions – Alkanes, Aromatic, Baeyer-Villiger, Enzymes in organic synthesis –
esters, amide, peptide , Modified and Artificial Enzymes , Catalytic antibodies

TOTAL: 45 PERIODS
OUTCOMES:
 The knowledge on enzyme and enzyme reactions will be the key step in to proceed towards
various concepts in biotechnology.
 The theoretical and practical aspects of kinetics will provide the importance and utility of
enzyme kinetics towards research.
 The process of immobilization has been increased steadily in food, pharmaceutical and
chemical industries and thus this study will provide simple and easy method of implementation.
 Ideas on Processing, Production and Purification of enzymes at an industrial scale will be
helpful to work technologically.

TEXT BOOKS:
1. Trevor Palmer , 5th edition Enzymes Horwood Publishing Ltd, 2001
2. Faber K , Biotransformations in Organic Chemistry, 2nd Edition , Springer

REFERENCES:
1. Harvey W. Blanch, Douglas S. Clark, Biochemical Engineering, 2nd Edition, CRC Press, 1997
2. James M. Lee, Biochemical Engineering, PHI, USA.
3. James. E. Bailey & David F. Ollis, Biochemical Engineering Fundamentals, 2nd
Edition, McGraw Hill Education; 2017.
4. Wiseman, Enzyme Biotechnology, Ellis Horwood Pub. Volume 4, 1980

41
BT3411 CHEMICAL ENGINEERING LABORATORY FOR L T P C
BIOTECHNOLOGISTS 0 0 3 1.5
OBJECTIVES:
 To provide basic understanding of chemical engineering principles and operations
 Course will enable the students to apply the principles in other chemical engineering and
biotechnology subjects offered in higher semesters

EXPERIMENTS
1. Flow measurement - Orifice meter
2. Flow measurement - Venturimeter,
3. Flow measurement - Rotameter
4. Pressure drop in flow through pipes
5. Pressure drop in flow through packed column
6. Pressure drop in flow through fluidized beds
7. Characteristics of centrifuge pump
8. Filtration through plate and frame filter press
9. Filtration in leaf filter
10. Heat transfer characteristics in heat exchanger
11. Simple and steam distillation

Equipment Needed for 30 Students

Colorimeter 2
Filter leaf 1
Orifice meter 1
Venturimeter 1
Rotameter 1
Glassware, Chemicals, Media as
required

OUTCOMES:
Upon completion of this practical course the student will
 Have knowledge on the basic principles of chemical engineering
 Be able to apply the skill of material balance and energy balance in unit operations unit
process of chemical engineering and biotechnology
 Be able to analyze the principles of chemical engineering and its applications in
chemical, mechanical and biological perspectives
 Understand the design and working principles of fluid moving machinery and transport
phenomena

TOTAL: 45 PERIODS

42
BT3461 ANALYTICAL INSTRUMENTATION LABORATORY L T PC
0 0 3 1.5
OBJECTIVES:
To train the students
• To have a practical hands on experience on Absoprtion Spectroscopic methods
• To acquire experience in the purification by performing chromatography
• To validate and analysis using spectrometric and microscopic techniques

EXPERIMENTS 60
1. Precision and validity in an experiment using absorption spectroscopy .
2. Validating Lambert-Beer’s law using KMnO4
3. Finding the molar absorbtivity and stoichiometry of the Fe (1,10 phenanthroline)3 using
absorption spectrometry.
4. Finding the pKa of 4-nitrophenol using absorption spectroscopy.
5. UV spectra of nucleic acids.
6. Chemical actinometry using potassium ferrioxolate.
7. Estimation of SO4-- by nephelometry.
8. Estimation of Al3+ by Flourimetry.
9. Limits of detection using aluminium alizarin complex.
10. Chromatography analysis using TLC.
11. Chromatography analysis using column chromatography.

Equipment Needed for 20 Students

Colorimeter 2
Glassware, Chemicals, Media as required
TOTAL: 45 PERIODS
OUTCOME:
• The students would visualize and interpret the theory of spectroscopic methods by hands
on experiments.

REFERENCES:
1. Skoog, D.A. etal. “Principles of Instrumental Analysis”, Vth Edition, Thomson / Brooks –
Cole,1998.
2. Braun, R.D. “Introduction to Instrumental Analysis”, Pharma Book Syndicate, 1987.
3. Willard, H.H. etal. “Instrumental Methods of Analysis”, VIth Edition, CBS, 1986.
4. Ewing,G.W. “Instrumental Methods of Chemical Analysis”, Vth Edition, McGraw-Hill, 1985.

43