Sop Dogs and Cats Sedation
Sop Dogs and Cats Sedation
Sop Dogs and Cats Sedation
These SOPs were developed by the Office of the University Veterinarian and reviewed by Virginia Tech
IACUC to provide a reference and guidance to investigators during protocol preparation and IACUC
reviewers during protocol review. They can be used as referenced descriptions for procedures on IACUC
protocols. However, it is the sole responsibility of the Principal Investigator to ensure that the referenced
SOPs adequately cover and accurately represent procedures to be undertaken in any research project. Any
modification to procedure as described in the SOP must be outlined in each IACUC protocol application
(e.g. if the Principal Investigator plans to use a needle size that is not referenced in the SOP, simply state
that alteration in the IACUC protocol itself).
Table of Contents
Version: 1
Original date: 12/12/17
Version date: 12/12/17
SOP: SEDATION IN DOGS AND CATS
1
SOP: SEDATION IN DOGS AND CATS
ii. Heating pads and blankets may be utilized until a rectal temperature of ≥ 99°F is
recorded and the animal able to ambulate from MDL 3 to its housing area.
Sedation Protocols
1. Acepromazine 0.05 mg/kg IM
2. Acepromazine 0.05 mg/kg and Morphine 0.5 mg/kg IM
3. Dexmedetomidine 0.01 mg/kg IM
4. Dexmedetomidine 0.005 mg/kg and Butorphanol 0.2 mg/kg IV
5. Midazolam 0.2 mg/kg and Butorphanol 0.2 mg/kg IM
6. Morphine 1 mg/kg IM
Additional drugs
1. Naloxone 0.005mg/kg IV or 0.04 mg/kg IM (reversal for opioids)
2. Atipamezole IM dose is the same volume used of dexmedetomidine (reversal for
dexmedetomidine)
3. Glycopyrrolate 0.005-0.01 mg/kg or atropine 0.02 to 0.04 mg/kg IV or IM (in case of severe
bradycardia or as directed by the veterinary laboratory instructors)