Report Text Covid-19
Report Text Covid-19
Report Text Covid-19
Corona Virus Disease 2019 (COVID-19) is an RNA virus, with a typical crown-like
appearance under an electron microscope due to the presence of glycoprotein spikes on its
envelope.This virus has the largest viral RNA (30 kb in length), which is single-stranded,
positive in sense, and polyadenylated. Coronaviruses are disseminated widely among
humans, other mammals, and birds, further causing acute respiratory diseases. At the end of
2019, a series of pneumonia cases of unknown cause emerged in Wuhan,China . A few weeks
later, in January 2020, deep sequencing analysis from lower respiratory tract samples
identified a novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as
causative agent for that observed pneumonia cluster . On February 11th, 2020, the World
Health Organization (WHO) named the disease caused by the SARS-CoV-2 as "COVID-19",
and by March 11th, 2020 when the number of countries involved was 114, with more than
118,000 cases and over 4000 deaths, the WHO declared the pandemic status.
Many studies have reported that bats may be the primary reservoirs of the disease. The first
confirmed case of COVID-19 outside China was diagnosed on 13th January 2020 in
Bangkok, Thailand . On the 2nd of March 2020, 67 territories outside mainland China had
reported 8565 confirmed cases of COVID-19 with 132 deaths, as well as significant
community transmission occurring in several countries worldwide, including Iran and Italy
and it was declared a global pandemic by the WHO on the 11th of March 2020. The number
of confirmed cases is constantly increasing worldwide and after Asian and European regions,
a steep increase in cases is currently (31 March 2020) being observed in low-income
countries Currently, COVID-19 is a pandemic that according to the latest WHO report, until
January 30, 2021, a total of 108,000,000 cases were infected in more than 216 countries
around the world, and 2.380.000 cases died.
Respiratory droplets are the major transmission route of this disease and transmission among
people occurs through direct (cough, sneeze, and droplet inhalation) and indirect (contact
with oral, nasal, and eye mucous membranes) routes. Human to human transmission of this
infection occurs mostly among family members, including relatives and friends who are in
close contact with patients or carriers. At the beginning, infection rapidly advances to organs
resulting in symptoms such as acute respiratory distress syndrome (ARDS), shock, acute
kidney failure, acute cardiac failure, and even death in severe cases. Patients may
demonstrate normal or lowered white blood cell counts, lymphopenia, thrombocytopenia with
greater thromboplastin activation time, and raised C-reactive protein level. Furthermore,
occupational exposure to health-care workers is another concern. Older people with
underlying diseases such as asthma, heart failure, diabetes, and Immunodeficiency diseases
are at a higher risk of a more severe COVID-19 disease.