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    GABRIEL JONATHAN 22010323140059 E6a4

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    RIfki ARYANANDA aji
    The document summarizes a lab report on examining the effects of chemical modifiers on heart rate. The student completed pre-lab quizzes, made predictions about how various drugs would affect heart rate, recorded experimental data, and answered post-lab questions. The drugs tested included pilocarpine, atropine, epinephrine, and digitalis. Pilocarpine decreased heart rate as expected by acting as an acetylcholine agonist. Atropine increased heart rate by blocking acetylcholine. Epinephrine increased heart rate by stimulating the sympathetic nervous system. Digitalis decreased heart rate by increasing the force of cardiac contractions.

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    GABRIEL JONATHAN 22010323140059 E6a4

    Uploaded by

    RIfki ARYANANDA aji
    31 views6 pages
    The document summarizes a lab report on examining the effects of chemical modifiers on heart rate. The student completed pre-lab quizzes, made predictions about how various drugs would affect heart rate, recorded experimental data, and answered post-lab questions. The drugs tested included pilocarpine, atropine, epinephrine, and digitalis. Pilocarpine decreased heart rate as expected by acting as an acetylcholine agonist. Atropine increased heart rate by blocking acetylcholine. Epinephrine increased heart rate by stimulating the sympathetic nervous system. Digitalis decreased heart rate by increasing the force of cardiac contractions.

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    GABRIEL JONATHAN 22010323140059 e6a4(1)

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    The document summarizes a lab report on examining the effects of chemical modifiers on heart rate. The student completed pre-lab quizzes, made predictions about how various drugs would affect heart rate, recorded experimental data, and answered post-lab questions. The drugs tested included pilocarpine, atropine, epinephrine, and digitalis. Pilocarpine decreased heart rate as expected by acting as an acetylcholine agonist. Atropine increased heart rate by blocking acetylcholine. Epinephrine increased heart rate by stimulating the sympathetic nervous system. Digitalis decreased heart rate by increasing the force of cardiac contractions.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    31 views6 pages

    GABRIEL JONATHAN 22010323140059 E6a4

    Uploaded by

    RIfki ARYANANDA aji
    The document summarizes a lab report on examining the effects of chemical modifiers on heart rate. The student completed pre-lab quizzes, made predictions about how various drugs would affect heart rate, recorded experimental data, and answered post-lab questions. The drugs tested included pilocarpine, atropine, epinephrine, and digitalis. Pilocarpine decreased heart rate as expected by acting as an acetylcholine agonist. Atropine increased heart rate by blocking acetylcholine. Epinephrine increased heart rate by stimulating the sympathetic nervous system. Digitalis decreased heart rate by increasing the force of cardiac contractions.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 6

    Name: e6a4- Gabriel-22010323140059

    Exercise 6: Cardiovascular Physiology: Activity 4: Examining the Effects of Chemical Modifiers on Heart Rate Lab Report Pre-lab

    Quiz Results
    You scored 100% by answering 4 out of 4 questions correctly.

    1. The parasympathetic nervous system releases to affect heart rate.


    You correctly answered: d. acetylcholine

    2. A cholinergic drug that worked the same as acetylcholine would You


    correctly answered: c. be an agonist and decrease heart rate.

    3. Norepinephrine affects the heart rate by


    You correctly answered: a. increasing the rate of depolarization and increasing the frequency of action potentials.

    4. The receptor binds norepinephrine and epinephrine. You


    correctly answered: b. ß-1 adrenergic

    09/25/23 page 1
    Experiment Results
    Predict Question:
    Predict Question 1: Pilocarpine is a cholinergic drug, an acetylcholine agonist. Predict the effect that pilocarpine will have on heart
    rate.
    Your answer : b. Pilocarpine will decrease heart rate.

    Predict Question 2: Atropine is another cholinergic drug, an acetylcholine antagonist. Predict the effect that atropine will have on
    heart rate.
    Your answer : c. Atropine will have no effect on heart rate.

    Stop & Think Questions:


    Which of the following is true of epinephrine?
    You correctly answered: c. It increases the heart rate and mimics the sympathetic nervous system.

    The final chemical modifier we will look at is digitalis (also known as digoxin and digitoxin and derived from the foxglove plant).
    Individuals with weakened hearts need to allow maximum time for venous return and increased stroke volume and would therefore
    most likely benefit from
    You correctly answered: c. increased force of contraction and decreased heart rate

    Experiment Data:

    Solution Heart Rate


    ---- 60
    Epinephrine 80
    Pilocarpine 45
    Atropine 70
    Digitalis 42

    09/25/23 page 2
    09/25/23 page 3
    09/25/23 page 4
    Post-lab Quiz Results
    You scored 100% by answering 4 out of 4 questions correctly.

    1. Pilocarpine decreased the heart rate. Typical of cholinergic agonists, it You


    correctly answered: b. decreased the frequency of action potentials.

    2. The effect of atropine was to


    You correctly answered: c. mimic the sympathetic nervous system.

    3. The modifiers tested that decrease the heart rate were You
    correctly answered: c. digitalis and pilocarpine.

    4. To increase the heart rate, the best choices would be You


    correctly answered: b. epinephrine and atropine.

    09/25/23 page 5
    Review Sheet Results
    1. Describe the effect that pilocarpine had on the heart and why it had this effect. How well did the results compare with your
    prediction?
    Your answer:
    it decreases the HR. it stimulate the parasymphatethic nerves

    2. Atropine is an acetylcholine antagonist. Does atropine inhibit or enhance the effects of acetylcholine? Describe your results
    and how they correlate with how the drug works. How well did the results compare with your prediction?
    Your answer:
    stimulates the frequency of SA, inhibits vagus nerve( block parasympathetic nerves)

    3. Describe the benefits of administering digitalis.


    Your answer:
    increases the force of contractions -decrease HR-increase stroke volume -Slows the sodium pump, which lets more Na+ accumulate
    heart muscle cells. -Less Na+ concentration gradient across the membrane -Na+/Ca+2 antiporters slow down so more Ca+2 remains
    inside the cardiac cells.

    4. Distinguish between cholinergic and adrenergic chemical modifiers. Include examples of each in your discussion. Your
    answer:
    -ACh, cholinergic, decreases HR -Epinephrine & Norepinephrine, adrenergic, increase HR.

    09/25/23 page 6

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