Aquarius
Aquarius
Aquarius
SUPERB VERSATILITY
to expand your library of methods, without delay, when a new Screen Scrolling
application arises within your laboratory.
CHOICE OF OPTICAL BANDWIDTH Scrolled Screen Width
Method Operation 430mm
SUPERB VERSATILITY
Any procedure may be stored as a method in the security code
protected integral memory of the Aquarius instruments. When a
Dynamic Scan Recall
method is recalled, all instrument parameters are automatically set, Full Reference Sample Space
without operator intervention, thus ensuring that the original
ACCURACY : FLEXIBILITY : FAST-OPERATION
conditions are exactly replicated. Method Storage
Tables of all peaks and valleys are produced together with Scan rate 1 to 4000nm/min
instrument, sample and operator details. Scans recalled from the
instruments integral memory or by dynamic scan recall are also fully Wavelength Precision 0.1nm
documented.
Straylight <0.02%
The screens shown are not two separate displays but part of a
continuous display viewed by scrolling. Validation Software
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POWERFUL INTEGRAL SOFTWARE
Sampling SCROLLING
DISPLAY Flexibility OF SCANS
The design of the double beam optical sampling allows
almost identical space and facilities in both the sample and
CHOICE OF OPTICAL BANDWIDTH
reference beams. Multi-cell reference sampling, with
temperature control is therefore possible.
DataStream
FULL VALIDATION PROCEDURES
Data may be transferred from the spectrophotometer to a
PC, or the software used to control the instrument from a
Multi-User Convenience WIDEST ACCESSORY RANGE
PC. Datastream software, developed by Cecil Instruments,
has a wide range of facilities including graphical and
Aquarius double beam instruments were designed
tabular presentation, normalisation of overlayed traces,
for the greatest convenience in a laboratory where
point and peak pick using a cursor, library facilities, data
multi user operation is required.
storage in files on disk, history logging and copy and paste
All methods, stored scans, plots, curves and data to other applications such as Excel, Word etc.
remain in secure integral memory, tamper
protected by passwords, readily accessible to all
operators without the possibility of mislaid disks The photograph below shows an Aquarius instrument in
or plug in card modules. use in Cecil Instruments applications laboratory.
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FULL REFERENCE BEAM SPACE
DISPLAY
DISPLAY SCROLLING OF SCANS
CHOICE
Curve and LineOF OPTICAL BANDWIDTH
Fitting
A straight line, quadratic or cubic curve may automatically be fitted to a
set of up to 30 standards. Fits may be made with an intercept or forced
SUPERB VERSATILITY
through zero. Replicate standards may be used for any given
concentration. All entries are prompted for simplicity of operation. A
quadratic curve fit is shown here.
Curve/Line Fit
Curve Storage
Editing of Standards
Absorbance Ratio
Absorbance Difference
Measurements in A, C, %T
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DISPLAY SCROLLING OF SCANS
SUPERB VERSATILITY
Optical Bandwidth
The Aquarius range provides the choice of fixed
bandwidth of less than 2nm, 1nm, or variable
ACCURACY : FLEXIBILITY : FAST-OPE
bandwidth of 0.5, 1, 2 and 4nm. The variable
resolution performance of the CE 7500 is ideal for
samples with sharper features requiring high
FULL VALIDATION PROCEDURES
resolution - particularly vapours and some liquid
samples.
Micro-Sipette Sampling
Samples of 300µl or less, and multiple samples, may be
measured with very low cross contamination.
Ultra-Micro Sampling
Valuable samples, such as biological samples prepared
with costly reagents, may be measured using a special
ultra-microcell and holder. With the system, samples of
50µl or even less may be accurately measured.
Tablet Dissolution
The CE 7460 and CE 7560 versions of Aquarius are fitted
with a special cell compartment and pipe port for tablet
dissolution assays.
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CHOICE OF OPTICAL BANDWIDTH
SUPERB VERSATILITY
VERSATILITY
This has been transformed into the Eadie-Hofstee format and plotted to give better precision in the calculation of
these important factors and constants.
Other transformations are available such as Lineweaver-Burk and the Hill plot for allosteric enzyme systems.
PC Data Manipulation
Band Quantification
Accurate quantitative assays using band area or height,
corrected for background absorption, are exceptionally
easy to carry out with the easy to use Aquarius
instruments.
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SUPERB VERSATILITY
ACCURACY : FLEXIBILITY
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:F
FAST
AST-OPERA
-OPERATION
TION
EDURES
SYSTEM FUNCTIONS SAMPLING
NGE
Integral Control System Variable or Fixed Bandwidth
All control software is within the instrument, tamper proof, Optical bandwidth selectable down to 0.5nm is provided by
providing easy menu driven operation with massive safe the CE7500 and allows the fine structure of narrow bands to
storage for scans, plots, curves etc. PC control and data be resolved which remain unresolved at just under 2nm
transfer to a PC are provided. bandwidth in instruments such as the CE7400.
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ACCURACY : FLEXIBILITY : FAST-OP
FULL VALIDA
VALIDATION
TION PROCEDURES
Instrument Validation
Assessment of instrument performance is readily
carried out using the validation software module built
into all Aquarius instruments and released by E-SEF,
‘Encoded software enhancement facility’.
The optical bandwidth of the instrument may be The Pharmacopoeia (EP/BP) test for absorbance
validated by measuring the half height width of the accuracy, using a 60mg/L solution of Potassium
narrow deuterium emission line at 656.1nm. The Dichromate in a 10mm pathlength cuvette, is shown
measurement is carried out automatically. here.
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FULL VALIDATION PROCEDURES
WIDEST ACCESSORY
ACCESSORY RANGE
ORDERING ACCESSORIES
Cell Holders Temperature Control - Water Circulation
Single cell holders - sample or reference 505 26 00 Single or micro sipette cell holder 503 36 00
Micro sipette 10mm cell holder 503 26 00 4 cell holder 202 36 16
Adjustable holder for micro cell 6600 57 00 2 x 4 cell holder, sample or reference 202 36 15
50µl ultra microcell holder 8020 39 00 6 cell holder 5500 36 15
Holder for rectangular cells up to 100mm 595 27 00 Temperature Control - Thermoelectric
Holder for cylindrical cells up to 100mm 595 26 00 Thermoelectric Control System 7400 31 00
Cell Changers Holder for single or sipette cell 8020 56 00
Auto changer for 4 or 4 + 4 cells, requires holder 9070 31 00 4 cell holder 9070 57 00
Holder for 4 x 10mm cells sample or reference 594 54 00 2 x 4 cell holder 9070 58 00
Auto changer for 6 cells, requires holder 9070 34 00 6 cell holder 9070 59 00
Holder for 6 x 10mm cells 5500 33 00 Sample Stirring
Holder for 6 x 20mm cells 5500 34 00 Electronic stirrer and sample cell holder 7200 31 00
Automatic 8 cell changer with holder 9070 32 00 Electronic stirrer and sample and reference holder 7200 32 00
4 position microcell holder 505 38 00 Gel Scanning
Sipette and Batch Sampling Gel scanner - requires trough or film holder 9070 39 00
Return sipette system, requires holder and cell 9070 21 00 Gel trough - 5mm x 100mm silica 570 07 02
10mm sipette cell 202 07 02 Printers and Cables
20mm sipette cell 202 07 51 RS232 cable for 25 pin PC with protocol manual 2021 26 00
40mm sipette cell 202 07 54 RS232 cable for 9 pin PC with protocol manual 2021 83 00
Sipette 10mm cell holder 503 26 00 Laser Printer 8000 73 01
Batch sampler for 40 samples with pump 2020 82 00 Dot matrix printer 8000 70 01
Batch sampler for 100 samples with pump 2020 82 02 Colour ink jet printer 8000 72 01
Reflectance Calibration Filters
Fixed angle reflectance accessory - pair CE 575 Holmium filter in holder 202 01 44
Variable angle reflectance accessory CE 574 Didymium filter in holder 303 01 30
Lamps Set of 2 certified Wavelength filters in holders 303 40 00
Deuterium lamp with hours indicator 2202 01 42 Set of 4 certified Absorbance filters in holders 594 44 00
Tungsten halide lamp - in pairs 2303 01 40 Set of 6 certified Absorbance filters in holders 594 66 00
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ORDERING
ORDERING
CE 7400 Spectrophotometer
< 2nm pharma-compliant Optical
bandpass. Wavelength range 190-1100nm.
SPECIFICATIONS
SPECIFICATION
Optical System Fully symmetrical double beam system CE 7400S Spectrophotometer
1 nm Optical bandpass.
All mirrors coated for long life SPECIFICATIONS
Wavelength range 190-1100nm.
Monochromator Modified Czerny-Turner design using 1200
CE 7500 Spectrophotometer
L/mm holographic diffraction grating 0.5, 1, 2 and 4nm Optical bandpass.
Detectors Two silicon diode detectors Wavelength range 190-1100nm.
Self Test and Calibration Automatic at switch on CE 7200 Spectrophotometer
Wavelength Range and Accuracy 190 - 1100nm; 0.5nm <2 nm Optical bandpass.
Wavelength range 190-900nm.
Wavelength Reproducibility 0.1nm
Wavelength Readout Digital display on screen CE 7460/CE 7560 Dissolution Spectros
Wavelength Selection By GOTO Key and keypad entry Suitable for tablet dissolution monitoring
using a choice of dissolution software and
Optical Bandwidth < 2nm CE7400; 0.5, 1, 2, 4nm CE7500 an automatic six or eight cell changer.
Stray Light Less than 0.02% at 220nm, NaI; and 0.02%
8000 70 01 Dot Matrix Printer and Cable
at 340nm, NaNO2
Display Screen Large backlit LCD displays spectra, menus, 8000 72 01 Colour Ink Jet Printer and Cable
data, prompts and instrument status. 8000 73 01 Laser Printer and Cable
Display Scrolling Provides viewing width of 430mm
Derivative Spectra 1st to 4th derivatives SOFTWARE MODULES
Autozero Automatic by press button
Program C
Photometric Readout Digital display of A, %T and C on screen Cell program for up to 4, 6 or 8 cells
Photometric Accuracy ±.004A at 1A
Program W
Photometric Noise Less than ±0.0001A at 550nm, 2nm b/width Wavelength program for up to 10
Baseline Stored in non-volatile memory wavelengths and time interval
measurements at a fixed wavelength
Baseline Flatness ±0.001A (300nm/min, 200-1100nm) 2nm
bandwidth Quant M
Baseline Stability Better than ±0.0001A/hour Multi-wavelength assays at 2 or 3
wavelengths, Warburg and Christian
Computer Interface Bi-directional RS 232 c assays at 2 or 3 wavelengths, wine/colour
Scan Speeds 1-4000nm/min assay at up to 10 wavelengths
Wavelength Scale Expansions 1-100nm/cm Quant P
Method Storage 30 methods may be stored and retrieved Protein assays using Lowry, Bradford,
Method Protection Each protected by 4 digit passcode Biuret, BCA and direct UV
Reaction Kinetics With plots, reprocessing of data as Quant S
required, for single cell or up to 6 cells Quantification of corrected bands,
difference spectra, spectral stripping
Overlaid Scans Up to 8 scans may be overlaid
Cell Programming Up to 4, 6 or 8 cells Kinetics
Programme Cycles From 1 to 9999 Kinetic measurements with plots and
reprocessing of data
Programme Delay (cycle time) From 0 seconds to 4 days (1 sec resolution)
Wavelength Programming Up to 10 wavelengths. May be combined Kinetics M
Multi-cell Kinetics linked with
with a cell programme autochanging of cells and plotting of
Dynamic Scan Recall Last 25 scans automatically stored on board reaction curves
Storage of Spectra 100 spectra may be stored code protected
Formulae
Concentration Curve Fitting Linear, quadratic or cubic with editing of Construction and entry of mathematical
standards. 30 curves may be stored formulae with multiple wavelengths and
cells; automatic computation of results
Multi-language Operation Six languages provided
Formula Entry and Computation Complex formulae may be computed Validation
Batch Sampling Up to 100 samples under internal control Validation of absorbance, wavelength,
bandwidth, stray light etc. using liquid
Date and Time Information Printed from real time clock samples or certified standards
Power Requirements 110-250V, 50/60Hz, 170 watts.
DataStream
Dimensions and Weight 635 x 410 x 210mm; 33kg Data transfer to, or control by a PC.
Graphical presentation, transfer of data to
Cecil Instruments policy is one of continuous development. We therefore reserve the right to change specification without notice. Excel, Word etc.
CECIL INSTRUMENTS LIMITED MILTON TECHNICAL CENTRE CAMBRIDGE CB24 6AZ ENGLAND ISO 9001
TEL: 01223 420821 FAX: 01223 420475 E-MAIL: [email protected] WEB SITE: www.cecilinstruments.com CERTIFIED COMPANY
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