Sustainability 15 12520
Sustainability 15 12520
Sustainability 15 12520
Review
The Utilization of Jackfruit (Artocarpus heterophyllus L.) Waste
towards Sustainable Energy and Biochemicals: The Attainment
of Zero-Waste Technologies
Prakash Kumar Sarangi 1,† , Rajesh Kumar Srivastava 2,† , Akhilesh Kumar Singh 3, * ,
Uttam Kumar Sahoo 4, * , Piotr Prus 5, * and Paweł Dziekański 6
Abstract: The valorisation of food and fruit wastes has the potential for the production of sustainable
energy and biochemicals. Approximately 70% of the weight of the original jackfruit (Artocarpus
heterophyllus L.) fruit is lost during its processing as waste in the form of peeled skin and core, both of
which have not been utilized and, thus these contribute to disposal as well as pollution issues. The
major components such as cellulose and hemicellulose can be easily biologically transformed into
bioenergy sources such as ethanol, methanol, and butanol; valuable phenolics and biotechnological
Citation: Sarangi, P.K.; Srivastava, products such as pectin, citric acid, bromelain, ferulic acid, and vanillin; and many other products.
R.K.; Singh, A.K.; Sahoo, U.K.; Prus,
These residues can also be utilized as essential sources for the biological transformation process,
P.; Dziekański, P. The Utilization of
leading to the production of numerous products with added value, such as phenolic antioxidants,
Jackfruit (Artocarpus heterophyllus L.)
phenolic flavour compounds, and organic acids. Thus, the value addition of jackfruit waste can
Waste towards Sustainable Energy
support sustainable solutions towards food and nutritional security. In this way, zero waste can be
and Biochemicals: The Attainment
of Zero-Waste Technologies.
achieved through novel biorefineries, which are critically highlighted in this paper. Furthermore,
Sustainability 2023, 15, 12520. novel technologies for the conversion of jackfruit waste are summarized with recent findings.
https://doi.org/10.3390/
su151612520 Keywords: jackfruit waste; zero waste; bioconversion; bioenergy; phenolic; biochemical
are also utilized as potential substrates for energy production and nitrogen-free extracts
(NFE ~65%). The rind of the ripe fruit is a good source for cattle foods and this waste of
jackfruit is a non-edible portion (~59.2%), such as perianth meal, rind, and core meal. This
waste matter is utilized for total dry meal recovery (11.6%) [2]. Some analyses have been
performed on jackfruits waste compositions (for perianth meal, rind, and core meal), which
contain ash (6 to 7.5%), carbohydrates (20–29%), crude protein (8–10.6%), crude fate (1.7 to
7.3%), and crude fibres (12–17.3%). Some studies have been conducted on the utilization of
jackfruit wastes and these are used for food, feed, and other industry applications. Some
non-edible portions of jackfruit (such as peels and axis) are reported with edible products
(seed), and still, these waste matters are underutilized worldwide such as in Bangladesh,
India, and other countries [3]. Different waste portions of jackfruits are generated during
juicy edible bulbs. The thick peels of jackfruits can be utilized for different valuable product
generations such as biofuel, non-porous adsorbents, and nutrient-enriched cattle feeds.
Normally, non-porous adsorbent is used in the removal of dye. The peel and central axis
of the jackfruit are also utilized for pectin extraction [4]. Its seed power is reported to be
used in various bakery products. From this fruit, seed powder, starch, and protein fraction
are isolated and then utilized in their purified form for food formulations at the industry
level [1,3,4].
While jackfruit has massive potential with unlimited benefits, its waste products
are much more than those of any other tropical fruits. According to Sundarraj and Ran-
ganathan [5], 75% of the jackfruit products in India get wasted due to inadequate mar-
keting, negligence, and a lack of processing facilities, and it is estimated that almost
20,000 million Indian rupees worth of jackfruit waste are reported only in the two Indian
states of Karnataka and Kerala, which are major jackfruit-producing states. The non-edible
parts of jackfruit that form the waste, however, can be made effective to use by bioconver-
sion using various technologies. For example, the thick peel of jackfruit can be converted
into nutrient-enriched cattle feed, for the extraction of biofuel, or into a nano-porous ab-
sorbent for removing dye, etc. The fruit waste can be a promising source of food and feed.
Though several reports are available on value-added products from the edible parts of
jackfruit, the conversion of jackfruit waste into various new value-added products using
the latest technological interventions is somewhat limited. Thus, there is an urgent need
to document and make a comprehensive review on the enormous jackfruit waste during
the pre- and post-harvest stages and the use of this waste towards sustainable energy
generation, leading to zero waste via various novel technologies.
2. Literature Review
Jackfruits have been analysed during different seasons by various workers [4–8] for
their nutritional and antioxidant properties. The findings of these studies have indicated
that jackfruits serve as a valuable source in the development of nutraceuticals, which
are currently in high demand worldwide [6]. Jackfruits in different seasons are reported
to differ in phytochemicals such as phenolics, terpenoids, steroids, glycosides, saponins,
alkaloids, and tannins and these compounds are known to possess antioxidant properties.
Diversity in the secondary metabolites in jackfruit has been reported and attributed to
variations in functionally, nutritionally, and medically important jackfruit wastes [4,6].
From jackfruit waste, antibacterial and antioxidant activity agents/compounds can be
evaluated from the extracts that are obtained from methanol extract from jackfruit leaves
and stem barks, and then they are applied as a peel-off mask. From the extraction of
these properties from jackfruit waste, the first raw material was macerated using the
methanol agent and then filtrates were evaporated for some time to obtain a concentrated
crude extract [6]. This extract was evaluated using different tests such as phytochemistry
screening and also antibacterial tests on Propionibakerium acnes and Staphylococcus aureus
at different concentrations of extracts using the DPPH (a,a-diphenyl-β-picrylhydrazyl)
method [8].
Sustainability 2023, 15, 12520 3 of 30
For the best evaluation of these phytochemicals, some additional tests have been
performed that can prove the characteristics of peel-off masks, such as homogeneity, pH,
organoleptic, and irritation tests. Some phytochemical screenings have proved the dom-
ination of tannin and saponin in these extracts [7,8]. In the context of jackfruit waste,
these are rich sources of carbohydrates, protein, fats, and phytochemicals. This organic
extraction or utilization serves as a promising feedstock for valuable bioproducts, includ-
ing fuels/chemicals synthesis. Several pre-treatments (such as biological, physical, and
chemical, including green solvents) have been applied as effective valorisation strategies
for jackfruit waste matters [9]. The implementation of these strategies has facilitated the
transformation of waste into products that possess added value, including, but not limited,
to bioethanol, biogas, bioplastic, feeds, and functional compounds/food additives. The
utilization of jackfruit waste for bioenergy production and recovery represents a promis-
ing avenue for sustainable and eco-friendly food waste-based renewable resources. This
approach offers an economically feasible alternative to non-renewable fossil fuels [10].
Further efforts have been performed on efficient bioconversion tasks/techniques, applied
for jackfruits that can generate/produce valuable biomaterials/chemicals, and this is only
to be achieved via a microbial fermentation process. This conversion can help to obtain
sustainable products with the mitigation of jackfruit generation/accumulation and support
for a green environment. Some reports have claimed the utility of jackfruit peel for the
remediation of dye colour from contaminated aquatic environments [8,9]. The implemen-
tation of said technology has the potential to facilitate the creation of an environmentally
sustainable economic framework cantered on the repurposing of waste materials. Many
studies have been carried out on the utilization of jackfruit waste for the production of
value-added products, with the ultimate goal of mitigating waste generation and promot-
ing environmental sustainability. In an attempt to utilize jackfruit waste, the production
of plastic from jackfruit seed starch has also been carried out. The resulting plastic was
strengthened through the incorporation of microcrystalline cellulose (MCC) derived from
cocoa pod husks, with glycerol serving as the plasticizer [11]. This study aimed to identify
the optimal mass and volume of microcrystalline cellulose (MCC) and glycerol concentra-
tion for the production of bioplastics in a high yield. Before the bioplastic production, MCC
bio-production was achieved with cocoa pod husks, and these husks were subjected to a
pre-treatment task with the help of alkali agents, bleaching, and an HCl acid solution to
obtain effective hydrolysis [12]. In this, the degree of crystallinity of the MCC determination
was carried out with the help of analytical techniques such as XRD (X-ray diffraction), with
a functional groups determination using FTIR (Fourier-transform infrared) and also a mor-
phological properties analysis using scanning electron microscopy (SEM). Some researchers
have relied on results for isolated MCC from pod husks and discussed it as a rod-like form
with a respective length (5–10 µm) and diameter (11.63 nm) with a high crystallinity [11,13].
From the isolated MCC utility in bioplastic synthesis, the tensile property of bioplastic
was determined at a starch to MCC mass ratio (8:2). Further tasks were performed in
addition to 20% glycerol with a measured tensile strength (0.637) and good elongation (at
break of 7.04%) [14]. From analytical measurements using FTIR spectroscopy for bioplastic
functional groups studies, greater numbers of -OH groups were found in bioplastics, and
these were reinforced with filler MCC, with the representation of a hydrogen bond [11,14].
Biofuels such as biodiesel, an eco-friendly and renewable biofuel, have emerged as a
cutting-edge substitute for petroleum-based diesel. This fuel possesses comparable traits
to conventional fossil fuels and exhibits a remarkably low emission profile. The adoption
of biodiesel not only seeks to diminish the reliance on non-renewable resources, but also
fosters economic growth while boosting energy security, as detailed previously [15]. Never-
theless, through an exhaustive exploration of the existing scientific literature, it becomes
evident that the untapped potential of jackfruit waste in promoting sustainable energy
and achieving zero waste remains largely unexplored [16]. The scarcity of research has
left unanswered questions about the true potential of jackfruit waste as a feedstock for
combustion and bioenergy generation [16]. To bridge this knowledge gap, it becomes im-
Sustainability 2023, 15, 12520 4 of 30
perative to delve into the scientific exploration of jackfruit waste combustion. For instance,
several research endeavours have investigated the untapped possibilities of jackfruit and
its byproducts, encompassing edible fruit, seeds, peels, and latex-like filaments (rags or
perianth) [17,18]. These comprehensive investigations have been centred on evaluating the
nutritional content, mineral composition, and physicochemical properties of these diverse
components. However, previous studies have convincingly established that jackfruit and
its waste harbour essential elements such as potassium, magnesium, and calcium, which
play pivotal roles in facilitating the catalytic process of biodiesel synthesis [15,17]. In the
realm of scientific research, an intriguing area yet to be fully explored lies in the use of
jackfruit waste, such as jackfruit peel waste (JPW), as a catalyst in biodiesel production.
Presently, the open literature is conspicuously void of significant investigations into the
production and application of JPW biomass catalysts, creating a stimulating challenge for
researchers [16,17]. The scarcity of information concerning JPW biomass catalysts serves
as the impetus behind investigations on the same, as it endeavours to bridge the existing
knowledge gap in the realm of catalyst development for biodiesel production. By focusing
on JPW, an abundantly available agricultural waste material, the research attempts to
transform it into a valuable resource, i.e., catalysts that proficiently convert waste cooking
oil (WCO) into biodiesel [16–18]. This is supported by the fact that using the K2 O from
JPW ash as a cost-effective solid catalyst for biodiesel generation is feasible. By leveraging
JPW biomass as a distinct solid catalyst, this approach bears several merits. Foremost, it
upholds environmental friendliness by repurposing an agricultural waste product that
would otherwise be discarded, thus contributing to waste reduction and fostering sustain-
ability in biodiesel production [18]. The catalyst proves renewable, reusable, recyclable,
non-hazardous, and environmentally benign, with vast applications across diverse fields.
Aligned with these principles, Mulkan et al. [15] diligently conducted their investigation,
culminating in compelling evidence showcasing the successful application of JPW as a
solid catalyst for biodiesel synthesis. Further, the United Nations has taken significant
steps toward ensuring a sustainable future for the entire world by 2030 [15,19]. One of its
key initiatives involves the establishment of the Sustainable Development Goals (SDGs),
with SDG 7 specifically focusing on promoting the sustainable utilization of bioresources
to increase the proportion of renewable energy in the global energy mix. Additionally,
SDG 7 aims to provide sustainable energy services to all nations [15,18]. Over the past few
decades, considerable efforts have been made to adopt cleaner and greener technologies
that harness various bioresources. These endeavours have led to the continuous implemen-
tation of innovative technologies [18,19]. Considering these, the present review aimed to
highlight the approaches/methods (with their advantages, limitations, and drawbacks)
employed for the transformation of jackfruit waste into sustainable energy/biochemicals
and advances made in the field, together with the emerging trend of utilizing jackfruit
waste as a bio-absorbent to combat and alleviate pollution-related issues.
approach to waste management [21]. Our scrutiny extended to exploring the practical
implementations of conversion technologies for jackfruit waste, meticulously evaluating
their cost-effectiveness and limitations within the broader global context. Throughout this
review, we elucidated how the utilization of jackfruit waste holds immense promise for
augmenting the share of renewable energy in the global energy mix while ensuring a strict
adherence to environmental safeguards [19,20]. Altogether, this review has provided a
compelling description that not only highlighted the abundant potential of jackfruit waste
valorisation, but also emphasized its pivotal role in fostering a greener, more sustainable
future for our planet [20,21].
cost/price, and sometimes this jackfruit cost/price can be reached at a high rate in the
year [26]. Most people in the world use jackfruits in their ripe form as tasty fruits with
a high sweetness and also high nutritive values. In their ripe form, jackfruits are good
sources of vitamins A and C, with some people believing they aid in the digestion process
and using them for ailments on a regular basis [25,26].
of jackfruits. The kernel of the seeds can constitute from nearly 90 to 95% of their weight
and then pulp can account for 30%, and can be found in between 70 and 80% of jackfruits
components as non-edible [35]. In regard to the non-edible parts of these fruits, their
outer rinds, perianth, and central core can consist of 60% of the total waste of jackfruits as
discarded parts. Jackfruit peels and its conical carpel apices are also important components
of jackfruit waste. Apart from this waste, jackfruit leaves can be also used for some medical
benefits, such as relieving fever, boils, wounds, and skin conditions [34,35]. Then, the
young fruits of jackfruit can exhibit acrid and astringent properties and characteristics,
and it can help in addressing flatulence in human health. Jackfruit seeds can be found
as rich sources of protein concentrations (5 to 6%). In each jackfruit tree, nearly 100 to
200 fruits can be produced, as it is a large and evergreen tree every year. Up until now, very
limited research has been performed on the unutilized waste of jackfruits, such as peels and
fibre that contribute nearly 60% of the whole fruit, as the largest known edible fruits from
any plants. Jackfruit pulp and seeds are known to contain various bioactive compounds
in addition to waste nutrients. The availability of these compounds in the fruit of this
plant can vary, as reported in a previous study [36]. The cultivation of this plant species is
feasible during the monsoon season in coastal areas. The fruit of this plant is considered
to be a cost-effective source of sustenance and is widely accessible at a low market value.
Subsequent investigations have been conducted on the underutilized segments of jackfruit,
with a focus on mitigating the accumulation of biowaste to promote the eradication of
pathogenic microorganisms in augmented agricultural yields [37]. The nutritional and
functional characteristics of jackfruit peels warrant further investigation for the purpose of
Sustainability 2023, 15, x FOR PEER REVIEW 7 of 31
extracting bioactive compounds that may be utilized in the pharmaceutical industry [37,38].
Figure 2 shows the different jackfruit wastes with their valorised products.
Figure 1.
Figure Production of
1. Production of jackfruit
jackfruit waste.
waste.
Figure2.2.Jackfruit
Figure Jackfruitwaste
wastevalorisation
valorisationinto
intodifferent
differentbioproducts.
bioproducts.
The
Theouter
outerlayer
layerof
ofjackfruit
jackfruitcomprises
comprisespeel peelthat
thatexhibits
exhibitsaa spiky
spiky pattern
pattern on on its
its surface.
surface.
The
The peel of jackfruit is considered to be non-edible and is regarded as a potentialwaste
peel of jackfruit is considered to be non-edible and is regarded as a potential waste
material.
material. Normally,
Normally, this
this part
part of
of the
the fruit
fruit is
is discarded,
discarded, but but recently,
recently, itit has
hasbeen
been used
usedforfor
fertilizer
fertilizer sources.
sources. These
These parts of jackfruit
parts of jackfruit can
can bebe used
used toto feed
feed the
the cattle
cattlein invillages.
villages.ItItisisa
agood
goodsource
sourceofofcarbohydrates
carbohydrates(up (upto to 24%),
24%), protein
protein (up
(up toto 9%),
9%), and
and fibre
fibre (17.3%)
(17.3%) [39].
[39].
Jackfruit
Jackfruit peels are utilized as valuable raw materials for functional ingredients such
peels are utilized as valuable raw materials for functional ingredients such asas
steroids,
steroids,triterpenoids,
triterpenoids,saponins,
saponins,and andcarbohydrates.
carbohydrates. In In jackfruit
jackfruit peel,
peel, more
morequantities
quantitiesof of
polyphenols
polyphenolsare arereported
reportedandandthis
thisisislinked
linked to to the
the peel
peel proximity
proximity with
with extrinsic
extrinsic domains.
domains.
Some
Someabiotic
abioticstress parameters/factors
stress parameters/factors (such
(suchas daylight, ultraviolet
as daylight, radiation,
ultraviolet and climatic
radiation, and cli-
induction) can impact the synthesis of polyphenols in the complete part of jackfruit peel [40].
matic induction) can impact the synthesis of polyphenols in the complete part of jackfruit
Other bioactive compounds in antioxidants can aid the chemical reactions in the human
peel [40]. Other bioactive compounds in antioxidants can aid the chemical reactions in
body and then help to offset the damages mediated by oxidation reactions. The pectin
the human body and then help to offset the damages mediated by oxidation reactions.
content in jackfruits is reported to contain 9 to 15% of dry weight and can make it a valuable
The pectin content in jackfruits is reported to contain 9 to 15% of dry weight and can
source of polysaccharides [39,40]. The extraction of various compounds is also used in
make it a valuable source of polysaccharides [39,40]. The extraction of various com-
the textile, paper, and biofuel sectors, with rich sources of celluloses. This can provide
pounds is also used in the textile, paper, and biofuel sectors, with rich sources of cellu-
alternative options to commercialized celluloses in the pharmaceutical industry [41,42].
loses. This can provide alternative options to commercialized celluloses in the pharma-
ceutical
4.3. Wasteindustry
towards [41,42].
Sustainable Energy and Biochemicals: The Attainment of
Zero-Waste Technologies
The harnessing of waste biomass for the derivation of high-value bioproducts presents
a prospective avenue in the pursuit of sustainable waste governance for many fruits [43].
For example, diverse pathways for valorisation have been delineated for discarded orange
peels, encompassing avenues such as biofuel production, biorefinery processes, pectin
extraction methodologies, and the formulation of nutritive animal feed additives [44]. The
residual matter arising from banana consumption emerges as a propitious and compatible
Sustainability 2023, 15, 12520 9 of 30
Figure 3.
Figure Schematic representation
3. Schematic representation of
of jackfruit
jackfruit plant
plant parts
parts with
with its
itswaste
wasteconversion
conversioninto
intovalue-
val-
added products.
ue-added products.
with the capability of achieving a higher yield of products compared to conventional ones.
These techniques have received more attention in the last few years due to having more
advantages [59,60]. Some techniques in the context of green/non-conventional mechanisms
are discussed below.
In the enzyme-assisted extraction (EAE) process, the enzyme concentration, composi-
tions, particle size, water-to-solid ratio, and also hydrolysis time play important roles and
can influence the yield/concentration of bioactive compounds. Some compounds such as
carotenoid extraction (from pumpkin waste) and anthocyanin from (Crocus sativus/grape
fruit waste) have been achieved using the EAE process [61,62]. Some bioactive compounds
such as phenolics (18–20 mgg−1 ) have been extracted from grape mare seed wastes with
the help of pectinase enzyme activity [60]. Other efforts have been made towards antioxi-
dant phenol extraction from apple pomace by using the commercial enzyme Pectinex Ò® ,
and then phenolics recovery (87%) from grape residues using Celluclast Ò® . The EAE-
based technique is very effective in enhancing the recovery of enzymes such as pectinase,
cellulases, and pectinases from jackfruit waste [63,64].
The second extraction method is known as ultrasound-assisted extraction (UAE),
and it has a number of uses and benefits, including a larger yield, desired quality, and a
straightforward procedure with minimal impact on the environment. The UAE approach
uses the ideal frequency range (20–2000 kHz) and is well renowned for being both straight-
forward and inexpensive. It can be effective at two different aspects, such as diffusion
over the cell wall and washing the contents following cell disintegration [65,66]. Due to
the wave creation of matrix expansion and compression, the UAE operating mechanism
causes/generates a cavitation phenomenon. The desired compounds are then extracted by
causing the cell membrane to become permeable [66]. Researchers have investigated the
many processes of the UAE process, including the acceleration of mass transfer, the disinte-
gration of the particles, and the improvement in solvent accessibility. For this technique,
samples of liquid–liquid or liquid–solid processing are frequently employed. Pressure,
temperature, frequency, and sonication duration are other parameters that might affect
the UAE process [65–67]. Recent research on UAE has revealed the widespread use of this
procedure and showed its effects on yield and compound characteristics. Some excellent
instances of UAE frequency have been documented for energy at or above 20 kHz, which
changes the physical–chemical characteristics of phytochemicals by causing the produc-
tion of free radicals [67]. Figure 4 establishes the sophisticated processing methodologies
employed for the extraction of bioactive compounds.
Some efforts towards tannin extraction from Avaram shell have been reported with the
application of the UAE technique and it uses 100 W of power. The UAE-based process has
shown its impact through the improved yield (160%) of tannins at 100 W. This improvement
in the yield of tannin has been explored and was found due to the improved mass transfer
of cell components and a way of leaching of tannin via this power [68]. Other bioactive
compounds, such as a good yield (caffeic acid ~64.3 µg/g, ferulic acid ~1513 µg/g, and
p-coumaric acid ~140 µg/g) of phenolic acids via the UAE technique, have been reported
with a better improvement compared to conventional techniques (maceration extraction)
for the same bioactive compounds from the same wastes [69]. Temperature and prolonged
time impact on UAE are found in the form of a low yield of phenolic compounds from
citrus peels. Some comparative studies have been performed on the maceration and UAE
technique performances in terms of consumed/required time period for the extraction
of bioactive compounds. A reduced time period (1 h) was found for the UAE technique
compared to maceration-assisted extraction (72 h) for phenolic compounds from Punica
granatum fruits. The extraction of polysaccharides using the UAE technique resulted in a
good yield, proving it to be an efficient technique [67–69].
Sustainability2023,
Sustainability 2023,15,
15,12520
x FOR PEER REVIEW of3031
12 of
Figure4.4.Green
Figure Greenextraction
extractionfor
forbetter
betteryield
yieldofofbioactive
bioactivecompounds
compoundsfrom
fromjackfruit
jackfruitwaste.
waste.
Yet
Someanother
efforts green extraction
towards tannin technique
extraction isfromknown Avaramas pulse
shellelectric
have beenfield-assisted
reported with ex-
traction (PEF-AE), a non-thermal process that allows a direct
the application of the UAE technique and it uses 100 W of power. The UAE-based process current to produce, which
helps produce
has shown its aimpact
better through
yield of bioactive
the improved compounds.
yield (160%) In thisof technique,
tannins at the 100 application
W. This im-
ofprovement
a high voltage current/pulse is passed through the materials
in the yield of tannin has been explored and was found due to the improved that are kept/placed be-
tween two electrodes for a short time period (in the range of
mass transfer of cell components and a way of leaching of tannin via this power [68]. microsecond to millisecond
periods). During compounds,
Other bioactive the passage of the as
such electric
a good current
yieldthrough
(caffeic the
acidsuspension
~64.3 µg/g,offerulic
cells, this
acid
can influence the cell structures to be destroyed and then
~1513 µg/g, and p-coumaric acid ~140 µg/g) of phenolic acids via the UAE technique, molecules can separate with
respect
have beento the appliedwith
reported charge [70]. improvement
a better This techniquecompared can function in a batch and
to conventional also in
techniques
continuous modes. For this technique’s performance, various factors such as field strength,
(maceration extraction) for the same bioactive compounds from the same wastes [69].
energy, pulse number, temperature, and material properties can affect/influence the yield
Temperature and prolonged time impact on UAE are found in the form of a low yield of
of the extraction and can work based on designing a process for a better performance. The
phenolic compounds from citrus peels. Some comparative studies have been performed
application of PEF-assisted extraction can be performed with phenolic compounds and also
on the maceration and UAE technique performances in terms of consumed/required time
the anthocyanins extraction process from different wastes [71,72]. PEF-assisted extraction
period for the extraction of bioactive compounds. A reduced time period (1 h) was found
with maceration on grape skin can be applied for the stability of the compound during
for the UAE technique compared to maceration-assisted extraction (72 h) for phenolic
vinification and can reduce the time of extraction. Some studies have been conducted on
compounds from Punica granatum fruits. The extraction of polysaccharides using the
untreated control samples along with PEF-treated samples with the maceration extrac-
UAE technique resulted in a good yield, proving it to be an efficient technique [67–69].
tion process/technique [70,71]. This has shown improved colour and also anthocyanin
Yet another green extraction technique is known as pulse electric field-assisted ex-
content/yields with enhanced polyphenol contents in wastes such as jackfruit [72]. Fur-
traction
ther impacts(PEF-AE),
of PEF atreatment
non-thermal can beprocess
foundthat allows
in the a direct current
wine-making process, to with
produce, which
a reduced
helps produce
maceration timea andbetter yield
also an of bioactivewine
improved compounds. In this technique,
quality [73–76]. the application
The cytomembrane in theof
a high voltage current/pulse is passed through the materials that
plant tissue’s cell walls can influence the movement of intracellular material between cells.are kept/placed between
twoapproach
This electrodesfor forextracting
a short time periodsubstances
bioactive (in the range of microsecond
is intriguing becausetoitmillisecond
may triggerperi- the
ods). During the passage of the electric current through the
cytomembrane in the tissue to disintegrate, which changes its permeable characteristics,suspension of cells, this canas
influence
well the cell mass
as increasing structures
transferto be destroyed
across andleading
the cells, then molecules
to highercan separate
yields [74,75].with respect
to the applied charge [70].
Advanced/green This technique
extraction techniques canutilize
function in a batch andradiation
electromagnetic also in continuous
and this
is transferred in the form of waves in a frequency range (300 MHz–300strength,
modes. For this technique’s performance, various factors such as field GHz) with energy,
the
pulse number, temperature, and material properties can
common use of a frequency of 2450 MHz. This can be found to be equivalent to 600 affect/influence the yield of the
to
extraction
700 and can
W of energy andworkthis based
energyon designing
can be absorbed a process
during forthe
a better
passage performance. The ap-
of the microwave
plicationa of
through PEF-assisted
suitable medium. extraction
This mediumcan be converts
performed withthermal
it into phenolicenergy
compounds and also
by facilitating
theprocessing
the anthocyanins extraction
[76,77]. Someprocess
bioactive from different wastes
compounds such as [71,72]. PEF-assisted
flavonoids extraction
from Terminalia
with maceration
bellerica plant haveonbeen grape skin can
reported bybe applied
using this for the stability
technique of the compound
and microwaves in the during
MAE
vinification and can reduce the time of extraction. Some studies have been conducted on
Sustainability 2023, 15, 12520 13 of 30
technique can result in a maximum yield (83%), with higher yields while compared to those
of conventional techniques (flavonoid yield ~64%). The MAE technique uses microwave
energy for heating the solvents with samples and is also influenced by operating conditions
such as temperature and feed ratio on flavonoid yield. The same extraction was applied
for hesperidin compound extraction with a better yield (48%) from the skin of Citrus
unshiu fruits [78,79]. During this technique, the extraction temperature showed a high
impact on the bioactive compound yield, and at 140 ◦ C, it showed a decreased hesperidin
quantity/content due to the interference of the other solubilized substance. This compound
influence has been found in the inhibition of hesperidin crystal [77,79]. Other conditions
impact waste matter maturity level in the case of peels, and matured peels have yielded
fewer hesperidin contents compared to immature peels (more than three times). Some
impacts of power in the MAE technique have been reported and this was found for
phenolic compound extraction from chokeberries. A better yield of phenolic compounds
(420.1 equivalent mg gallic acid/100 g chokeberries) was reported at 300 W for 5 min [80,81].
The extraction of silibinin from Silybum marianum waste with the help of the MAE technique
is discussed with a better yield (97.3%), and this was higher than that of conventional
approaches. A similar study was performed on this technique’s efficiency and it was
reported for phenolic compounds from apple pomace waste [82]. The compound extraction
yield from this technique is influenced by several factors/parameters such as solubility,
dielectric constant, dissipation factor (d), and solvent nature. The higher recovery of
flavonoids using MAE (up to 74%) is reported and it is better than that of the traditional
recovery/extraction process (up to 70.5%), with proof of an efficient process [83,84].
During the supercritical fluid extraction process (SC-FE), the desired compound ex-
traction is carried out by using the solvent above the critical point (CP), and this CP can
be found as a specific temperature (Tc) or pressure (Pc) point. However, above the CP,
gas and liquid cannot exist as separate phases [85]. At the CP, fluids/solvents can exhibit
the liquid (in terms of density) and salvation power/gas (viscosity, diffusion, and surface
tension). These properties can facilitate a higher yield of bioactive compounds within a
short time. In the case of supercritical fluid extraction (SFE), there is a need for a good
mobile tank (consisting of a CO2 pump), solvent vessel, oven, controller, and also a trapping
vessel [85,86]. Now, most bioactive extraction is achieved through the application of green
technologies compared to conventional methods, and in this context, supercritical CO2
extraction is discussed with a better yield of naringin from citrus paradise. This approach
uses ethanol as a modifier (14% by wt.) at the same process conditions such as a 58.6 ◦ C
temperature and 9.5 MPa pressure [87]. This technique is applied for phenolic compound
extraction from rice wine lees wastes, with the uses of Soxhlet extraction (SE) and SFE. It
was compared with the yield of bioactive compounds with a reduced time period extraction
(1 h compared to 6 h in the case of the traditional extraction technique), with less ethanol
needed and a better yield of phenols (43%) [88]. In the process of SFE, carbon dioxide is
a common solvent used in food sector tasks and it is safe with easily attainable critical
conditions (at 30.9 and 73.8 bar) for food processing. Some major limitations such as a low
polarity are disclosed, but they can be improved by using polar solvents such as methanol,
ethanol, dichloromethane, and acetone [87,88]. These can work as modifiers with the
capability of improving their solvating power and also enhancing their extraction efficiency
with minimum/no interaction between analytes and matrices. Some parameters such as a
low diffusibility of the solvent into the matrix, an extended extraction time, high-pressure
requirements, and expensive infrastructures can also be found as some challenges to this
technique [86,87]. Further, the consistency and reproducibility during the continuous
process can be found as some more limitations of this extraction technique and these can
prevent the scalability of this technique [87,89].
its complex organic matter. These strategies help in the valorisation of jackfruit waste
into value-added products, including fuels (bioethanol or biogas) and other bioproducts
(bioplastic, feeds, or functional food additives) [90]. From jackfruit waste, nowadays, bioen-
ergy production and promotion have also been carried out by several research groups and
jackfruit waste can be utilized as a renewable resource. It is also an eco-friendly and cost-
effective process for generating alternative fuel options to fossil fuel [91]. In recent years,
the efficient bioconversion of jackfruit waste into several types of fuel sources has been
performed with the help of the microbial fermentation process by using different microbes
such as bacteria, yeast, and fungi [84,85]. Yeast (such as Saccharomyces cerevisiae for ethanol),
bacteria (such as Methanosarcina barkeri and Methanococcus maripaludis for methane), and
fungi (such as Rhizopus oryzae MNT 006, Aspergillus oryzae MNT for ethanol) have been
reported for biofuel production [24,49,92]. These efforts can help with the reduction in
environmental pollution and also help with bioremediation processes (i.e., several toxic
dye removals) in water sources/aquatic environments that are contaminated with dye
colour. Some review papers have addressed colour dye removal from water bodies with
the help of jackfruit waste. This effort can solve several serious ecological problems in
jackfruit-producing nations [91,93].
Several reports have claimed a waste generation quantity of jackfruit in the range of 5
to 7 kg wt. per fruit, and its potential for conversion into a wide range of bio-products such
as biofuels, animal feeds, or bioactive components for use in the bakery and packaging
material industries. In the process of waste (including jackfruit waste) material hydrolysis,
physical, chemical, and biological pre-treatments processes are applied. These processes
help the conversion of waste into simple sugars in final production synthesis under the
effort of valorisation [94]. The utilization of jackfruit waste can result in several fuel product
syntheses/productions. These can be achieved by the application of pre-treatment and
extraction steps via the valorisation of waste biomasses in an effective and successful
manner. In recent years, a number of valorisation technologies have been developed for
jackfruit waste hydrolysis and, later, these have been used in the conversion of desired
products via the utilization of several bioprocesses/green extraction steps. Thus, they help
in promoting sustainable product utilization in the biorefinery and also the bioeconomy [13].
Normally, jackfruit is reported to contain 70–80% non-edible parts and out of this quantity,
60% of jackfruit wastes are the outer rind, perianth, and central core parts. A number of
analyses for the biochemical composition of jackfruit waste have been performed, with
the utilization of these wastes for the recovery of health benefit products [13,94]. The
peels of jackfruit waste are good sources of protein, cellulose, and pectin and then seed
waste is a good source of carbohydrate (76%), protein (18%), and lipid content (2%). In
the context of bioenergy production from jackfruit waste utilization, several types of pre-
treatment are applied as crucial steps with a conversion capacity from complex forms of
organic matter into simpler ones. The pre-treatment step in the complex organic matter
conversion process helps in the enzymatic reactions of hydrolysis during saccharification
processes, and this step can ensure the simple sugars’ form for fermentation with the
help of different microbial agents [95]. A good example of jackfruit waste conversion is
found in the ethanol production/extraction process. This process utilizes low-pressure and
also high-intensity ultrasound processes that affect the compositions and functionality of
the isolated proteins from jackfruit seeds [13,90]. Jackfruit waste has undergone several
processing tasks with a variety of physical methods to develop its valuable products, and
some of these are irradiation, microwave processing, super-critical fluid, and high-pressure
processing extraction, as common and advanced processing methods [95,96].
In an effort toward the hydrolysis of jackfruit wastes, several approaches/methods
of chemical treatment have been applied in acidic or alkaline solutions (low to high con-
centration) at temperatures of 130 ◦ C and 210 ◦ C via mixing the waste matter. During the
chemical-agent-assisted pre-treatment process, waste matter can be converted within a
few minutes to a few hours to obtain fermentable sugars depending on the pre-treatment
conditions [97,98]. Many researchers have applied these processes for methane production,
Sustainability 2023, 15, 12520 15 of 30
efficient energy generation, and also environmental benefits using jackfruit peels. The
effect of methane generation via the pre-treatment of jackfruit waste with 5% alkaline
hydrogen peroxide (AHP) has shown an enhanced methane yield, resulting in a higher
biodegradability (up to 70%) when compared to untreated waste matter [99]. Some studies
too have reported the potential of the annual energy production from jackfruits, treated
with a 5% AHP solution. Further, alkaline extraction techniques have been applied for the
isolation of starch from jackfruit seed waste, and this technique was found to extract 18%
starch from seeds [98,99].
Conventional chemical and physical pre-treatment processes require the costly in-
vestment of reagents, machinery, and energy before applying biological pre-treatments
for cellulosic and lignocellulosic matters in enzymatic saccharification processes [17,100].
During the biological treatment process, many living agents such as fungi/bacteria are used.
They utilize less energy and are thus more eco-friendly processes. Many microbial agents
are known to possess cellulolytic and hemicellulolytic activities that can be utilized for
jackfruit waste utilization [2]. Among several microbial systems, Saccharomyces cerevisiae is
applied for ethanol production from jackfruit waste—ethanol contains 35% oxygen content
and can be utilized for the burning process in the production of a lesser quantity of nitrogen
Sustainability 2023, 15, x FOR PEER REVIEW 16 of 31
and also particulate matters in the gasoline combustion process [2,99]. Figure 5 discusses
the pretreatment approaches for hydrolysis and also bioenergy development.
Figure 5. Jackfruit
Figure 5. Jackfruit waste
waste utilized
utilized for
for bioenergy
bioenergy task.
task.
4.4.1. Bioethanol
In the context of value-added product recovery from jackfruit waste, bioethanol pro-
duction from enzymatic hydrolysis and the microbial fermentation of cellulosic biomass,
including jackfruit wastes, has been discussed as a cost-effective and eco-friendly tech-
nique/approach [107]. In this fuel synthesis process, jackfruit wastes such as peel material
are utilized as a potential feedstock and this waste matter contains high quantities of
carbohydrate contents. A number of studies have been conducted for saccharifying jack-
fruit rind matter via the application of recombinant enzyme endoglucanase from Bacillus
subtilis strain MUS1 microbes at a temperature of 50 ◦ C and pH of 5.0 with 15 mg/mL of
substrate ratio/quantity [108]. This recombinant enzyme from Bacillus subtilis can help in
the generation of more quantities of sugars during the saccharification process of jackfruit
waste [51,107]. From different types of waste, bioethanol is produced as an alternative
energy source. These wastes are good sources of natural products such as carbohydrates
and these are utilized as a potential feedstock for ethanol production with the hydrolysis
and fermentation process. In this context, jackfruit seed is the best feedstock with rich
sources of carbohydrates [108,109]. A number of research studies have determined the
effect of pH on carbohydrate hydrolysis that can be utilized for bioethanol production. For
the hydrolysis of the carbohydrates from jackfruit seed, effective pre-treatments with a
pH-dependent process have been performed via the application of a separate fermentation
hydrolysis (SHF) process [109]. This process used a sulphuric acid solution as a hydrolysing
agent. Later, the fermentation process with the help of the S. cerevisiae strain was used in a
fermenter vessel at different pH values (such as 2, 3, and 5) over a 70 h period. From this
experiment’s results, it was claimed that an optimum glucose content (75%) and pH (3.0)
supported the high concentration of bioethanol (58%) in the fermentation broth [108–110].
From this research work, the fermentation stage’s role has been discussed and it was found
that a high concentration of glucose can push a high concentration of bioethanol with a
linear relationship [110]. This published paper talked about the glucose concentration and
high ethanol concentration from jackfruit seed waste, which have shown a high potential
for feedstock for bioethanol biosynthesis at a cheap price [108,110].
Bioethanol production from fermenting raw matter such as jackfruit waste is reported
with suitable microbial systems. During the fermentation process, the ethanol production
of jackfruit waste is reported with the application of the S. cerevisiae strain. This yeast
strain has shown a high capability for ethanol production, which is due to its natural
adaptation properties and also a highly tolerant sugar/ethanol/chemical inhibitor [111].
Ethanol can be synthesized by petroleum products or the fermentation process. In the
biological process, cellulose or hemicelluloses from jackfruit waste are hydrolysed and then
utilized for the ethanol production process. Most lignocellulosic biomass, including jack-
fruit waste, is a rich source of carbohydrates, and thus it needs an effective pre-treatment
process for fermentative sugars that can be used in ethanol production. Later, product
separation and purification processes are also needed to obtain pure ethanol [108,111].
For this bioethanol production, jackfruit peels were selected as potential substrates, and
then an enzyme/microbial system (S. cerevisiae) was used for obtaining the fermentative
sugars and ethanol. Thus, ethanol now can be present in alcoholic drinks, with more
uses of this yeast in the bakery industry and fermented food and alcoholic drink prepa-
ration/production [111,112]. Some efforts have been made towards jackfruit straw waste
and it has been processed with fermentation as a starter substrate. From this process,
bioethanol was separated via a distillation process. The starter mass and fermentation time
were checked to achieve the maximum ethanol yield with the utilization of yeast such as
S. cerevisiae and urea as N-nutrients [112].
An optimum yeast mass (40 g) of S. cerevisiae with a distillate volume of 13.6 mL
has been found after 96 h of fermentation time, with a distillate/ethanol yield of 15.2 mL.
Sustainability 2023, 15, 12520 17 of 30
However, under the optimal conditions for fermentation, the volume of the bioethanol
distillate was found to be 30 mL with a distillation temperature of 70–80 ◦ C. From this
approach to ethanol production, its refractive index (1.354), density (0.367 g/mL), and
boiling points (71–72 ◦ C) were reported [113]. In another report, bioethanol production
was discussed from the utilization of Sri Lankan rotten fruits (without skin), including
jackfruit waste. This ethanol was produced in a batch process with an optimization of
the fermentation process parameters [112,113]. In the optimization of the fermentation
process, some optimization techniques such as the Genetic Algorithm (GA), Response
Surface Methodology (RSM), and also Particle Swarm Optimization (PSO) were discussed.
During the bioethanol production, different overripe fruits were taken and these fruits
were jackfruit, papaya, and banana, with the use of two microbes under three fermentation
conditions. During these experiments, maximum ethanol yields were reported with the
RSM (13.4 vol. %), GA (13.4 vol. %), and PSO (13. 36 vol. %) with the use of banana variety
fruit fermentation and a Pseudomonas mendocina microbial strain (ratio~ 1:1), pH (5.1) and
temperature (35 ◦ C) [114,115].
4.4.2. Biogas
Biogas generation from different types of jackfruit waste is a good effort for sustainable
fuel sources. In this context, the potential of biogas production is found from different fruit
wastes such as banana peels, jackfruit waste, and pineapple waste, and these have been
used for co-digestion processes with cow dung to provide alternative energy sources [116].
During these experiments, substrates from each fruit waste were implemented into the
co-digestion process with varying ratios (0%, 25%, and 50%) of cow dung. This was
performed in laboratory-scale anaerobic digesters (up to a capacity of 250 mL) and was then
run for 30 days to generate or produce the biogas from different fruit wastes (jackfruit—
82.3 mL; banana fruit—189 mL; and pineapple fruit waste/peel—262 mL) [117]. In another
experiment in this study, jackfruit waste, pineapple waste, and banana peels were co-
digested with 25% cow dung, and the biogas production from these fruits increased by
two to three folds [117,118]. Cow dung is a very effective medium for biogas generation.
Studies have shown that a 50% cow dung ratio with these fruit wastes improves the biogas
yield by two folds. From these reported results, a mixture of jackfruit, banana peel, and
pineapple peel can be found in a much better biogas production yield and can help in
the energy supply chain process for our daily needs [118]. During the biogas generation
experiment, some efforts were made towards experimental design, digester set-up, and the
volume and biogas composition determination that were produced from the jackfruit waste,
banana, and pineapple peels with the cow dung. The biochemical methane potential (BMP)
assay protocol was applied for the anaerobic digestion process [119]. An evaluation process
for the biogas quality attributes was performed for a process that used jackfruit waste,
banana, and pineapple peels with cow dung in a batch digestion process. In this experiment,
an anaerobic system was found to have a 500 mL capacity and was submerged in a 20 L
temperature-regulating water bath and 250 mL measuring cylinder for the generated biogas
measurement task via the displacement method. The temperature of the water bath was
maintained at 36.5 ◦ C [116,119].
In the context of value-added product recovery, the utilization of jackfruits has been
reported and discussed for the production of biogas, biochar, and briquettes from jackfruit
waste. In many developing countries, huge potential is found due to the greater quantity of
organic waste accumulation that can then be utilized for conversion into many types of fuel
sources such as biogas generation [49,51]. Waste organic matter in rural areas due to small
holder farmers can be generated and then these can be utilized for different natures of
biofuel sources. In this context, biomass wastes such as jackfruit waste can be managed to
produce bioenergy with a mitigation of the GHG (greenhouse gases) emission quantity via
a well-managed way [120]. Now, the decomposition of organic matter can be minimized
via the generation of biogas, due to greater quantities of agricultural waste such as jackfruit
waste being utilized as cheap raw materials for the production of bioproducts such as
Sustainability 2023, 15, 12520 18 of 30
biofuels, biochar, and biopesticides with briquettes and others [121]. Biochar production
from waste matter is a good effort, and then biochar can be mixed with soils and help
to produce soils rich in carbon with a contribution to carbon dioxide sequestration and
soil fertility [122]. Some papers have focused on jackfruit waste utilization for biogas
production from an anaerobic digestion process with biochar and briquette production.
From the anaerobic process for jackfruit waste utilization, biogas can be produced [117,119].
It needs a high temperature for jackfruit waste decomposition tasks to help in biochar
production. This research effort can help to produce various product synthesis information,
with help in the mitigation of climatic changes and also carbon dioxide sinks in soil [49,122].
Sustainability 2023, 15, x FOR PEER REVIEW 19 of 31
Figure 6 discusses the jackfruit wastes with different microbial/chemical transformation
approaches for many products syntheses to support zero-waste generation.
Figure 6.
Figure 6. Jackfruit
Jackfruit wastes
wastes promote
promote zero-waste
zero-waste generation
generation and
and biorefinery
biorefinery promotion.
promotion.
4.4.3. Bioplastic
productionfrom
Bioplastic production fromthe Bacillus
the Bacillusmegaterium
megaterium strain
strain JHAJHA has been
has been reported,
reported, with
awith
highacapacity of this microbial
high capacity of thisstain. This microbe
microbial stain. was
This isolated
microbefrom wasoil-contaminated
isolated from
soils and then tested
oil-contaminated in the
soils andlaboratory
then testedon in
glucose substrate consumption,
the laboratory resultingconsump-
on glucose substrate in a high
quantity of polyhydroxyalkanoates
tion, resulting in a high quantity of(PHA) accumulation in this
polyhydroxyalkanoates microbe
(PHA) [123]. This plastic
accumulation in this
was biosynthesized
microbe [123]. Thisby B. megaterium
plastic with the utilization
was biosynthesized of jackfruit-waste-like
by B. megaterium seeds, with
with the utilization of
some inorganic or organic
jackfruit-waste-like seeds, matter/compounds.
with some inorganicThis waste matter
or organic was found to be
matter/compounds. suitable
This waste
for a high
matter was accumulation
found to be of PHAs inside
suitable microbial
for a high cells. Some
accumulation additional
of PHAs efforts
inside were made
microbial cells.
toward a characterization of the bioplastic layer that formed inside
Some additional efforts were made toward a characterization of the bioplastic layer thatthe cell due to the
PHAs [124]. Several viable applications of PHAs have been found in
formed inside the cell due to the PHAs [124]. Several viable applications of PHAs have medical science and
cosmetic
been found andinpharmaceutical
medical science product syntheses.
and cosmetic andFor the best synthesis
pharmaceutical of PHAs,
product advanced
syntheses. For
research
the best is needed with
synthesis an optimization
of PHAs, advanced of the process
research parameters,
is needed andoptimization
with an this could promote
of the
huge quantities
process of PHAs
parameters, andfrom
thischeaper
could feedstock
promote suchhugeasquantities
jackfruit wastes.
of PHAs Thisfrom
wastecheaper
matter
is
feedstock such as jackfruit wastes. This waste matter is a good source of carbon and for
a good source of carbon and nitrogen for finding an economically viable process ni-
commercial scale [123,124].
trogen for finding A further
an economically PHA
viable product
process foriscommercial
biodegradable scaleplastic and A
[123,124]. it fur-
has
shown
ther PHA an effective
product isand durable process.
biodegradable In an
plastic andeffort
it hastoward
shownjackfruit wasteand
an effective hydrolysis,
durable
biological pretreatment is a promising and eco-friendly process for
process. In an effort toward jackfruit waste hydrolysis, biological pretreatment is a complete conversion
promising and eco-friendly process for complete conversion into fermentable sugars
[125]. Biological pre-treatment needs optimal process parameters to achieve the complete
hydrolysis of waste biomass. The effect of pre-treatments such as physical and chemical
processes can enhance the impact of the enzymatic conversion of waste biomasses into
Sustainability 2023, 15, 12520 19 of 30
into fermentable sugars [125]. Biological pre-treatment needs optimal process parameters
to achieve the complete hydrolysis of waste biomass. The effect of pre-treatments such
as physical and chemical processes can enhance the impact of the enzymatic conversion
of waste biomasses into simple ones, achieving bioproduct synthesis [124,125]. Table 1
discusses more examples of bioenergy/other value-added products.
Table 1. Different value-added products (i.e., biofuel, bioplastic, enzymes, pectin, and nano-emulsion)
synthesis from jackfruit waste conversion via valorisation techniques.
Table 1. Cont.
good and the potential sources of valuable biomaterials and wastes from jackfruit plants are
a good source of carbohydrates, fats, proteins, and also phytochemicals [104–106]. In the
case of bioactive compounds from the wastes of fruits/vegetable sources, these have shown
a positive impact on human health via contributing to the modulation of metabolic pro-
cesses and also cellular activities [101]. Some bioactive compounds have shown properties
such as antioxidant, anti-cancer, anti-inflammation, and anti-allergenic. Some compounds
contribute to anti-atherogenic activity and these properties of bioactive compounds can
depend on their pathways and also their bioavailability in the human body. In terms of
the categories of bioactive compounds, some are hydrophobic in nature and they have
shown less bioavailability in the human body [102]. In this context, some efforts have been
made toward technological advancements such as nano-emulsion applications. This effort
helped in enhancing their stability and functional properties. Bioactive substances can be
obtained via traditional and non-traditional methods, each with their own set of benefits
and drawbacks [101,102]. Table 2 shows the bioactive compounds with health benefits from
jackfruit waste.
Table 2. Health benefits from bioactive compounds that are recovered from jackfruit waste matters.
Table 2. Cont.
have claimed that jackfruit leaves (JLP) are an important waste and are suitable as an
agro-waste categories-based material that can be utilized for the efficient removal of metal
(such as lead—Pb –II form) from wastewater. Due to the surface medication of jackfruit
leaf power (JLP), it can ably remove a high percentage of lead concentration [126]. Further,
the surface modification of jackfruit leaves has been achieved through the application
of chemical reagents such as isopropyl alcohol (20%), followed by treatment with alkali
sodium hydroxide (AIJLP) and tartaric acid (TIJLP). These modifications were confirmed
by the BET surface area (29 m2 /g). This chemical modification resulted in 1.5-fold and
2.5-fold increases in the surface area due to AIJLP (50 m2 /g) and TIJLP (72 m2 /g) impacts,
respectively [127]. After generating low-cost bioabsorbents from JLP, these can be applied
in batch experiments to confirm lead adsorption. There have been efforts too to find the
optimal equilibrium conditions such as pH, contact time, and lead concentration. Similarly,
from the developed bioabsorbsent, pore size and pore volume can also be analysed using
Barrett–Joyner–Halenda (BJH) models/methods [126,127]. The BJH model has helped to
provide the optimal parameters for the adsorption of toxic metal concentrations via this
biomaterial property mechanism. Recently, in reusability studies, it was confirmed that
AIJLP can efficiently remove lead contaminants/pollutants by up to 95% in up to five
cycles. These results have recommended the application of AIJLP for bioremediation in
wastewater [127]. The cost of developing bioadsorbents from jackfruit leaves and their
subsequent modifications with chemical reagents can cost up to 11 USD/kg. This includes
the cost of the collection of raw material, the washing and drying processes, and some
miscellaneous expenses until the chemical reagents are produced in their final form. This
is a very good example of low-cost bioadsorbents from jackfruit leaves [128,129]. Hence,
the sustainable utilization of jackfruit waste biomass can contribute to environmental
sustainability and energy access for rural populations [130]. The biowaste materials of
jackfruit byproducts act as sustainable sources for various bioenergy and biochemical
purposes [131–137].
of jackfruit waste sources, which have been analysed/studied for nutrient determination.
Further, different valorisation techniques such as green extraction, the preparation of bioac-
tive material approaches, and microbial fermentation were discussed in greater depth
with mechanisms for generating/recovering nutrients/bioproducts. These conversion
approaches have been found to be very effective in generating substantial amounts of
bioproducts from these wastes, thus making the environment clean and safe. This is a good
strategy for achieving zero waste in different conversion processes. The objectives of this
review were achieved by a detailed focus on the mitigation of jackfruit waste/the recovery
of nutrients with sustainable product development involving a zero-waste process.
Author Contributions: P.K.S., R.K.S. and A.K.S.: conceptualization; design of the study; formal
data analysis; writing original draft, review, and editing. U.K.S.: data curation; formal analysis;
methodology and typo—correction. P.P. and P.D.: methodology; review and editing of the manuscript.
All authors have read and agreed to the published version of the manuscript.
Funding: This work has received no specific funding.
Institutional Review Board Statement: There is no institutional review board statement.
Informed Consent Statement: There is no informed consent statement.
Data Availability Statement: Not applicable.
Acknowledgments: The authors acknowledge the support received from their concerned universities
for writing this report.
Conflicts of Interest: The authors declare no conflict of interest.
Abbreviations
AgNO3 : silver nitrate; AgNPs: silver nanoparticles; AHP: alkaline hydrogen peroxide; ASPE: Ar-
tocarpus heterophyllus seed powder extract; BMP: biochemical methane potential; BWR: bread waste
residues; CF: crude fibre; CP: critical point; CP: crude protein; DPPH: a,a-Diphenyl-β-picrylhydrazyl;
EAE: enzyme-assisted extraction; FTIR: Fourier-transform infrared; GA: Genetic algorithm; JSP:
jackfruit seed powder; MAE: microwave-assisted extraction; MB: methylene blue; MCC: microcrys-
talline cellulose; NFE: nitrogen-free extract; Pc: pressure point; PEF-AE: pulse electric field-assisted
extraction; PHA: Polyhydroxyalkanoates; POJ: peel of jackfruit; PSO: Particle Swarm optimization;
RSM: Response Surface Methodology; SC-FE: supercritical fluid extraction process; SE: Soxhlet
extraction; SEM: scanning electron microscopy; SHF: separate fermentation hydrolysis; Tc: specific
temperature; UAE: ultrasonic-assisted extraction; and XRD: X-ray diffraction.
References
1. Thanh, L.P.; Truong, P.; Kha, T.; Hang, T.T.T. Jackfruit leaves can totally replace traditional grass in the diet of lactating dairy
goats. J. Appl. Animal Res. 2022, 50, 97–102. [CrossRef]
2. Ranasinghe, R.A.S.N.; Maduwanthi, S.D.T.; Marapana, R.A.U.J. Nutritional and Health Benefits of Jackfruit (Artocarpus heterophyl-
lus Lam.): A Review. Int. J. Food Sci. 2019, 2019, 4327183. [CrossRef] [PubMed]
3. Chavan, S.; Yadav, B.; Atmakuri, A.; Tyagi, R.D.; Wong, J.W.C.; Drogui, P. Bioconversion of organic wastes into value-added
products: A review. Bioresour. Technol. 2022, 344, 126398. [CrossRef] [PubMed]
4. Bala, S.; Garg, D.; Sridhar, K.; Inbaraj, B.S.; Singh, R.; Kamma, S.; Tripathi, M.; Sharma, M. Transformation of Agro-Waste into
Value-Added Bioproducts and Bioactive Compounds: Micro/Nano Formulations and Application in the Agri-Food-Pharma
Sector. Bioengineering 2023, 10, 152. [CrossRef] [PubMed]
5. Sundaraaj, A.A.; Ranganathan, T.V. Jackfruit Taxonomy and Waste Utilization. Intern. J. Plant Res. 2018, 31, 67–73. [CrossRef]
6. Sreeja Devi, P.S.; Kumar, N.S.; Sabu, K.K. Phytochemical profiling and antioxidant activities of different parts of Artocarpus
heterophyllus Lam. (Moraceae): A review on current status of knowledge. Futur. J. Pharm. Sci. 2021, 7, 30. [CrossRef]
7. Siregar, A.B.; Bulan, R.; Yusak, Y. Antibacterial & antioxidant properties of leave & stem bark extract of Artocarpus heterophyllus as
the component of peel-off mask. Int. J. Sci. Technol. Eng. 2018, 5, 101–106.
8. Brahma, R.; Ray, S. A comprehensive review on the recent advances in the valorization of jackfruit waste for the development of
value-added products. J. Food Technol. Res. 2022, 9, 120–134. [CrossRef]
Sustainability 2023, 15, 12520 25 of 30
9. Sundarraj, A.A.; Ranganathan, T.V. Physicochemical characterization of Jackfruit Peel. Res. J. Pharm. Biol. Chem. Sci. 2017, 8,
2285–2295. [CrossRef]
10. Begum, R.; Aziz, M.G.; Yusof, Y.A.; Saifullah, M.; Uddin, M.B. Evaluation of gelation properties of jackfruit (Artocarpus
heterophyllus) waste pectin. Carbohydr. Polym. Technolog Applicat. 2021, 2, 100160.
11. Lubis, M.; Gana, A.; Maysarah, S.; Ginting, M.H.; Harahap, M.B. Production of bioplastic from jackfruit seed starch (Artocarpus
heterophyllus) reinforced with microcrystalline cellulose from cocoa pod husk (Theobroma cacao L) using glycerol as plasticizer.
IOP Conf. Ser. Mat. Sci. Eng. 2018, 309, 012100. [CrossRef]
12. Cagasan, C.U.; Lingatong, C.A.V.; Pore, K.M.T.; Raymond, V.; Restor, C.D.D.; Lauzon, R.D. Production and quality evaluation of
wine from jackfruit co-products. Internat. Life Sci. Biotechnol. 2021, 4, 340–352. [CrossRef]
13. Widjaja, C.; Djojorahardjo, Y.; Kurniawan, A.; Irawaty, W.; Soetaredjo, F.E. Biorefinery concept on jackfruit peel waste: Bio-oil
upgrading. ARPN J. Eng. Appl. Sci. 2018, 13, 2202–2207.
14. George, N.; Debroy, A.; Bhat, S.; Singh, S.; Bindal, S. Biowaste to Bioplastics: An Ecofriendly Approach for A Sustainable Future.
J. Appl. Biotechnol. Rep. 2021, 8, 221–233. [CrossRef]
15. Mulkan, A.; Zulkifli, N.W.M.; Husin, H.; Ahmadi; Dahlan, I.; Syafiie, S. Development of jackfruit (Artocarpus heterophyllus) peel
waste as a new solid catalyst: Biodiesel synthesis, optimization, and characterization. Process Saf. Environ. Prot. 2023, 177, 152–168.
[CrossRef]
16. Soetardji, J.P.; Widjaja, C.; Djojorahardjo, Y.; Soetaredjo, F.E.; Ismadji, S. Bio-oil from jackfruit peel waste. Procedia Chem. 2014, 9,
158–164. [CrossRef]
17. Da Alves, J.L.; da Silva, J.C.; Mumbach, G.D.; Di Domenico, M.; da Silva Filho, V.F.; de Sena, R.F.; Machado, R.A.F.; Marangoni, C.C.
Insights into the bioenergy potential of jackfruit wastes considering their physicochemical properties, bioenergy indicators,
combustion behaviors, and emission characteristics. Renew. Energy 2020, 155, 1328–1338. [CrossRef]
18. Weintraub, K.; Rodrigues, C.; Tabai, K. Perspectives on Sustainable Management of Jackfruit Trees for Food Consumption in Rio
de Janeiro, Brazil. Environ. Sci. Proc. 2022, 15, 8. [CrossRef]
19. Cabral, D.; Solórzano, A.; Oliveira, R. Florestas urbanas e urbanidades florestais no Rio de Janeiro–Uma Geografia Histórica.
Ambientes Rev. Geogr. E Ecol. Política 2020, 2, 174–227. [CrossRef]
20. Ruba, U.B.; Talucder, M.S.A. Potentiality of homestead agroforestry for achieving sustainable development goals: Bangladesh
perspectives. Heliyon 2023, 9, e14541. [CrossRef]
21. Hasan, M.K.; Ahmed, M.M.; Miah, M.G. Agro-economic performance of jackfruit-pineapple agroforestry system in Madhupur
tract. J. Agric. Rural. Dev. 2008, 6, 147–156. [CrossRef]
22. Meera, M.; Ruckmani, A.; Saravanan, R.; Prabhu, R.L. Anti-inflammatory effect of ethanolic extract of spine, skin and rind of jack
fruit peel–a comparative study. Nat. Prod. Res. 2018, 32, 2740–2744. [CrossRef] [PubMed]
23. Ojwang, A.R.; Muge, E.K.; Mbatia, B.; Mwanza, B.; Ogoyi, D. Comparative analysis of phytochemical composition and antioxidant
activities of methanolic extracts of leaves, roots and bark of jackfruit (Artocapus heterophyllus) from selected regions in Kenya and
Uganda. J. Adv. Biol. Biotechnol. 2017, 16, 1–13. [CrossRef]
24. Soumya, B.; Gupta, P.; Vikas, R.; Pradeep, K. Chemoenzymatic saccharification of Artocarpus heterophyllus Lam.(jackfruit) peel
waste and its utilization for bioethanol production. Indian. Forest 2019, 145, 1204–1209.
25. Kahar, A.W.; Lingeswarran, M.; Hulwani, M.Z.A.; Ismai, L.H. Plasticized jackfruit seed starch: A viable alternative for the partial
replacement of petroleum-based polymer blends. Polymer Bull. 2019, 76, 747–762. [CrossRef]
26. Marichelvam, M.K.; Manimaran, P.; Sanjay, M.R.; Siengchin, S.; Geetha, M.; Kandakodeeswaran, K.; Boonyasopon, P.; Gorbatyuk, S.
Extraction and development of starch-based bioplastics from Prosopis Juliflora Plant: Eco-friendly and sustainability aspects.
Curr. Res. Green. Sustain. Chem. 2022, 5, 100296. [CrossRef]
27. Ahmed, M.; Nasar, A. Utilization of jackfruit peel as a low-cost adsorbent for the removal of methylene blue dye from synthetically
polluted water. Curr. Anal. Chem. 2021, 17, 1016–1026. [CrossRef]
28. Butool, S.; Butool, M. Nutritional quality on value addition to jack fruit seed flour. Int. J. Sci. Res. 2015, 4, 2406–2411.
29. Sundarraj, A.A.; Ranganathan, T.V. Phytochemical constituents and thin-layer chromatography evaluation of the ethanolic extract
of jackfruit (Artocarpus integer) peel. J. Pharm. Res. 2018, 12, 717.
30. Pathak, N.; Singh, P.; Singh, P.K.; Sharma, S.; Singh, R.P.; Gupta, A.; Mishra, R.; Mishra, V.K.; Tripathi, M. Biopolymeric
nanoparticles based effective delivery of bioactive compounds toward the sustainable development of anticancerous therapeutics.
Front. Nutr. 2022, 9, 963413. [CrossRef]
31. Bhat, V.; Mutha, A.; Dsouza, M.R. Pharmacognostic and physiochemical studies of Artocarpus heterophyllus seeds. Int. J. ChemTech
Res. 2017, 10, 525–536.
32. Sundarraj, A.A.; Ranganathan, T.V. Phytochemical screening and spectroscopy analysis of jackfruit (Artocarpus integer Thumb.
peel. Int. Res. J. Pharm. 2017, 8, 151–159. [CrossRef]
33. Jagtap, U.B.; Bapat, V.A. Green synthesis of silver nanoparticles using Artocarpus heterophyllus Lam. seed extract and its
antibacterial activity. Ind. Crops Prod. 2013, 46, 132–137. [CrossRef]
34. Hanani, Z.N.; Husna, A.A.; Syahida, S.N.; Khaizura, M.N.; Jamilah, B. Effect of different fruit peels on the functional properties of
gelatin/polyethylene bilayer films for active packaging. Food Packag. Shelf Lif. 2018, 18, 201–211. [CrossRef]
Sustainability 2023, 15, 12520 26 of 30
35. Islam, M.; Haque, A.R.; Kabir, M.; Hasan, M.; Khushe, K.J.; Hasan, S.M. Fruit by-products: The potential natural sources of
antioxidants and α-glucosidase inhibitors. J. Food Sci. Technol. 2021, 58, 1715–1726. [CrossRef]
36. Jain, R.; Mendiratta, S.; Kumar, L.; Srivastava, A. Green synthesis of iron nanoparticles using Artocarpus heterophyllus peel extract
and their application as a heterogeneous Fenton-like catalyst for the degradation of Fuchsin Basic dye. Curr. Res. Green. Sustain.
Chemist. 2021, 4, 100086. [CrossRef]
37. Jancy, S.; Shruthy, R.; Preetha, R. Fabrication of packaging film reinforced with cellulose nanoparticles synthesised from jack fruit
non-edible part using response surface methodology. Internat. J. Biolog. Macromolec. 2020, 142, 63–72. [CrossRef]
38. Kalse, S.B.; Swami, S.B. Recent application of jackfruit waste in food and material engineering: A review. Food Biosci. 2022,
48, 101740. [CrossRef]
39. Surendrababu, K.; Kumar, S.S.; Anoop, C.T.; Nuhaiz, V.P. Emission characteristics of jackfruit peel oil with three-hole nozzle.
IOP Conf Ser. Materi. Sci. Eng. 2020, 993, 012010. [CrossRef]
40. Mardarveran, P.; Mokhtar, N.M. Analysis of Artocarpus heterophyllus peel as a natural coagulant using response surface methodol-
ogy (RSM). J. Technol. 2020, 82, 99–107. [CrossRef]
41. Brahma, R.; Ray, S. In-depth analysis on potential applications of jackfruit peel waste: A systematic approach. Food Chem. Adv.
2022, 1, 100119. [CrossRef]
42. Sundarraj, A.A.; Ranganathan, T.V.; Gobikrishnan, S. Optimized extraction and characterization of pectin from jackfruit (Artocarpus
integer) wastes using response surface methodology. Internat. J. Biologic. Macromolec. 2018, 106, 698–703. [CrossRef]
43. Sharma, P.; Vishvakarma, R.; Gautam, K.; Vimal, A.; Gaur, V.A.; Farooqui, A.; Varjani, S.; Younis, K. Valorization of citrus peel
waste for the sustainable production of value-added products. Bioresour. Technol. 2022, 351, 127064. [CrossRef] [PubMed]
44. De Medina-Salas, L.; Giraldi-Díaz, M.R.; Castillo-González, E.; Morales-Mendoza, L.E. Valorization of Orange Peel Waste Using
Precomposting and Vermicomposting Processes. Sustainability 2020, 12, 7626. [CrossRef]
45. Rincón-Catalán, N.I.; Cruz-Salomón, A.; Sebastian, P.J.; Pérez-Fabiel, S.; Hernández-Cruz, M.d.C.; Sánchez-Albores, R.M.;
Hernández-Méndez, J.M.E.; Domínguez-Espinosa, M.E.; Esquinca-Avilés, H.A.; Ríos-Valdovinos, E.I.; et al. Banana Waste-to-
Energy Valorization by Microbial Fuel Cell Coupled with Anaerobic Digestion. Processes 2022, 10, 1552. [CrossRef]
46. De la Peña-Armada, R.; Mateos-Aparicio, I. Sustainable Approaches Using Green Technologies for Apple By-Product Valorisation
as A New Perspective into the History of the Apple. Molecules 2022, 27, 6937. [CrossRef]
47. Jung, J.-M.; Kim, J.Y.; Kim, J.-H.; Kim, S.M.; Jung, S.; Song, H.; Kwon, E.E.; Choi, Y.-E. Zero-waste strategy by means of valorization
of bread waste. J. Clean. Product. 2022, 365, 132795. [CrossRef]
48. Zhang, C.; Kang, X.; Wang, F.; Tian, Y.; Liu, T.; Su, Y.; Qian, T.; Zhang, Y. Valorization of food waste for cost-effective reducing
sugar recovery in a two-stage enzymatic hydrolysis platform. Energy 2020, 208, 118379. [CrossRef]
49. Nsubuga, D.; Banadda, N.; Kabenge, I.; Wydra, K.D. Potential of Jackfruit Waste for Biogas, Briquettes and as a Carbondioxide
Sink-A Review. J. Sustain. Develop. 2020, 13, 60–75. [CrossRef]
50. Zhang, C.; Ling, Z.; Yang, L.; Liu, Y.; Cao, T.; Sun, Y.; Liu, W.; Huo, S.; Zhang, Z.H.; Su, H.; et al. Efficient caproate production
from ethanol and acetate in open culture system through reinforcement of chain elongation process. J. Clean. Product. 2023,
383, 135394. [CrossRef]
51. Nuriana, W. Wuryantoro, Ethanol Synthesis from Jackfruit (Artocarpus heterophyllus Lam.) Stone Waste as Renewable Energy
Source. Energy Proced. 2015, 65, 372–377. [CrossRef]
52. Ginting, M.H.S.; Misran, I.E.; Maulina, S. Potential of durian, avocado and jackfruit seed as raw material of bioethanol: A review.
IOP Conf. Ser. Mater. Sci. Eng. 2020, 801, 012045. [CrossRef]
53. Saini, A.; Panesar, P.S.; Bera, M.B. Valorization of fruits and vegetables waste through green extraction of bioactive compounds
and their nanoemulsions-based delivery system. Bioresour. Bioprocess. 2019, 6, 26. [CrossRef]
54. Štambuk, P.; Tomašković, D.; Tomaz, I.; Maslov, L.; Stupić, D.; Kontić, J.K. Application of pectinases for recovery of grape seeds
phenolics. 3 Biotech. 2016, 6, 224. [CrossRef]
55. Pathak, N.; Singh, S.; Singh, P.; Singh, P.K.; Singh, R.; Bala, S.; Thirumalesh, B.V.; Gaur, R.; Tripathi, M. Valorization of jackfruit
waste into value added products and their potential applications. Front. Nutr. 2022, 9, 1061098. [CrossRef]
56. Lal, A.M.N.; Prince, M.V.; Kothakota, A.; Pandiselvam, R.; Thirumdas, R.; Mahanti, N.K.; Sreeja, R. Pulsed electric field combined
with microwave-assisted extraction of pectin polysaccharide from jackfruit waste. Innovat. Food Sci. Emerg.Technolog. 2021,
74, 102844. [CrossRef]
57. Jiang, Z.; Shi, R.; Chen, H.; Wang, Y. Ultrasonic microwave-assisted extraction coupled with macroporous resin chromatography
for the purification of antioxidant phenolics from waste jackfruit (Artocarpus heterophyllus Lam.) peels. J. Food Sci. Technol. 2019,
56, 3877–3886. [CrossRef]
58. More, P.R.; Jambrak, A.R.; Arya, S.S. Green, environment-friendly and sustainable techniques for extraction of food bioactive
compounds and waste valorization. Tren. Food Sci. Technol. 2022, 128, 296–315. [CrossRef]
59. Azooz, E.A.; Ridha, R.K.; Abdulridha, H.A. The fundamentals and recent applications of micellar system extraction for nanoparti-
cles and bioactive molecules: A review. Nano Biomed. Eng. 2021, 13, 264–278. [CrossRef]
Sustainability 2023, 15, 12520 27 of 30
60. Belwal, T.; Chemat, F.; Venskutonis, P.R.; Cravotto, G.; Jaiswal, D.K.; Bhatt, I.D.; Devkota, H.P.; Luo, Z. Recent advances in
scaling-up of non-conventional extraction techniques: Learning from successes and failures. Trends Anal. Chem. 2020, 127, 115895.
[CrossRef]
61. Zhang, Z.H.; Wang, L.H.; Zeng, X.A.; Zhong, H.; Brennan, C.S. Non-thermal technologies and its current and future application
in the food industry: A review. Int. J. Food Sci. Technol. 2018, 54, 1–13. [CrossRef]
62. Nishad, S.; Saha, C. Kaur, Enzyme- and ultrasound-assisted extractions of polyphenols from Citrus sinensis (cv. Malta) peel:
A comparative study. J. Food Proc. Preserv. 2019, 43, e14046. [CrossRef]
63. Wan, N.; Kou, P.; Pang, H.-y.; Chang, Y.-h.; Cao, L.; Liu, C.; Zhao, C.-J.; Gu, C.-B.; Fu, Y.-J. Enzyme pretreatment combined with
ultrasonic-microwave-assisted surfactant for simultaneous extraction of essential oil and flavonoids from Baeckea frutescens.
Industr Crops Prod. 2021, 174, 19–21. [CrossRef]
64. Rafińska, K.; Wrona, O.; Krakowska-Sieprawska, A.; Walczak-Skierska, J.; Kiełbasa, A.; Rafiński, Z.; Pomastowski, P.; Kolankowski,
M.; Buszewski, B. Enzyme-assisted extraction of plant material—New functional aspects of the process on an example of Medicago
sativa L. Industr. Crops Prod. 2022, 187, 115424. [CrossRef]
65. Li, H.Z.; Zhang, Z.J.; Xue, J.; Cui, L.X.; Hou, T.Y.; Li, X.-J.; Chen, T. Optimization of ultrasound-assisted extraction of phenolic
compounds, antioxidants and rosmarinic acid from perilla leaves using response surface methodology. Food Sci. Technol. 2016, 36,
686–693. [CrossRef]
66. Shen, X.; Shao, S.; Guo, M. Ultrasound-induced changes in physical and functional properties of whey proteins. Int. J. Food Sci.
Technol. 2017, 52, 381–388. [CrossRef]
67. Živković, J.; Šavikin, K.; Janković, T.; Ćujić, N.; Menković, N. Optimization of ultrasound-assisted extraction of polyphenolic
compounds from pomegranate peel using response surface methodology. Sep. Purif. Technol. 2018, 194, 40–47. [CrossRef]
68. Sharayei, P.; Azarpazhooh, E.; Zomorodi, S.; Ramaswamyc, H.S. Ultrasound assisted extraction of bioactive compounds from
pomegranate (Punica granatum L.) peel. LWT-Food Sci. Technol. 2019, 101, 342–350. [CrossRef]
69. Silva, M.E.; Araújo, M.V.R.L.; Santana, A.A.; Silva, F.L.H.; Maciel, M.I.S. Ultrasound-assisted extraction of bioactive compounds
from ciriguela (Spondias purpurea L.) peel: Optimization and comparison with conventional extraction and microwave. Arabi J.
Chem. 2021, 14, 103260. [CrossRef]
70. Carpentieri, S.; Režek Jambrak, A.; Ferrari, G.; Pataro, G. Pulsed Electric Field-Assisted Extraction of Aroma and Bioactive
Compounds from Aromatic Plants and Food By-Products. Front. Nutr. 2022, 8, 792203. [CrossRef]
71. Pataro, G.; Carullo, D.; Ferrari, G. PEF-assisted supercritical CO2 extraction of pigments from microalgae nannochloropsis
oceanica in a continuous flow system. Chem. Eng. Trans. 2019, 74, 97–102. [CrossRef]
72. Pataro, G.; Carullo, D.; Siddique, M.A.B.; Falcone, M.; Donsì, F.; Ferrari, G. Improved extractability of carotenoids from tomato
peels as side benefits of PEF treatment of tomato fruit for more energy-efficient steam-assisted peeling. J. Food Eng. 2018, 233,
65–73. [CrossRef]
73. Pataro, G.; Bobinaite, R.; Bobinas, C.; Šatkauskas, S.; Raudonis, R.; Visockis, M.; Ferrari, G.; Viškelis, P. Improving the extraction
of juice and anthocyanins from blueberry fruits and their by-products by application of pulsed electric fields. Food Bioprocess.
Technol. 2017, 10, 1595–1605. [CrossRef]
74. Bobinaite, R.; Pataro, G.; Lamanauskas, N.; Šatkauskas, S.; Viškelis, P.; Ferrari, G. Application of pulsed electric field in the
production of juice and extraction of bioactive compounds from blueberry fruits and their by-products. J. Food Sci. Technol. 2015,
52, 5898–5905. [CrossRef] [PubMed]
75. Pataro, G.; Carullo, D.; Falcone, M.; Ferrari, G. Recovery of lycopene from industrially derived tomato processing by-products by
pulsed electric fields-assisted extraction. Innov. Food Sci. Emerg. Technol. 2020, 63, 102369. [CrossRef]
76. Alara, O.R.; Alara, J.A.; Obanijesu, E.O.; Mudalip, S.K.A. Extract-rich in flavonoids from Hibiscus sabdariffa calyces: Optimizing
microwave-assisted extraction method and characterization through LC-Q-TOF-MS analysis. J. Food Process Eng. 2020, 43, e13339.
[CrossRef]
77. Bagade, S.B.; Patil, M.; Bagade, S.B. Recent advances in microwave assisted extraction of bioactive compounds from complex
herbal samples: A review. Crit. Rev. Anal. Chem. 2021, 51, 138–149. [CrossRef]
78. Simić, V.M.; Rajković, K.M.; Stojičević, S.S.; Veličković, D.T.; Nikolić, N.Č.; Lazić, M.L.; Karabegović., I.T. Optimization of
microwave assisted extraction of total polyphenolic compounds from chokeberries by response surface methodology and artificial
neural network. Sep. Purif. Technol. 2016, 160, 89–97. [CrossRef]
79. Chuyen, H.V.; Nguyen, M.H.; Roach, P.D.; Golding, J.B.; Parks, S.E. Microwave-assisted extraction and ultrasound-assisted
extraction for recovering carotenoids from gac peel and their effects on antioxidant capacity of the extracts. Food Sci. Nutr. 2017, 6,
189–196. [CrossRef]
80. Vilariño, M.V.; Franco, C.; Quarrington, C. Food loss and waste reduction as an integral part of a circular economy. Front. Environ.
Sci. 2017, 5, 21. [CrossRef]
81. Alara, O.R.; Abdurahman, N.H. Microwave-assisted extraction of phenolics from Hibiscus sabdariffa calyces: Kinetic modelling
and process intensification. Ind. Crops Prod. 2019, 137, 528–535. [CrossRef]
82. Alara, O.R.; Abdurahman, N.H.; Adbul Mudalip, S.K. Optimizing microwave-assisted extraction conditions to obtain Phenolic
compounds-rich extract from Chromolaena odorata leaves. Chem. Eng. Technol. 2019, 42, 1733–1740. [CrossRef]
Sustainability 2023, 15, 12520 28 of 30
83. Alara, O.R.; Abdurahman, N.H.; Ukaegbu, C.I.; Azhari, N.H. Vernonia cinerea leaves as the source of phenolic compounds,
antioxidants, and anti-diabetic activity using microwave-assisted extraction technique. Ind. Crops Prod. 2018, 122, 533–544.
[CrossRef]
84. Alara, O.R.; Abdurahman, N.H.; Ukaegbu, C.I.; Alara, J.A. Optimization of microwave-assisted extraction of phenolic compounds
from Ocimum gratissimum leaves and its LC-ESI-MS/MS profiling, antioxidant and antibacteria activities. J. Food Meas. 2020, 14,
3590–3604. [CrossRef]
85. Espinosa-Pardo, F.A.; Nakajima, V.M.; Macedo, G.A.; Macedo, J.A.; Martínez, J. Extraction of phenolic compounds from dry and
fermented orange pomace using supercritical CO2 and cosolvents. Food Bioprod. Process. 2017, 101, 1–10. [CrossRef]
86. Argun, M.E.; Argun, M.Ş.; Arslan, F.N.; Nas, B.; Ates, H.; Tongur, S.; Cakmakcı, O. Recovery of valuable compounds from orange
processing wastes using supercritical carbon dioxide extraction. J. Clean. Prod. 2022, 375, 134169. [CrossRef]
87. Alara, O.R.; Abdurahman, N.H.; Ukaegbu, C.I. Soxhlet extraction of phenolic compounds from Vernonia cinerea leaves and its
antioxidant activity. J. Appl. Res. Med. Aromat. Plants. 2018, 11, 12–17. [CrossRef]
88. Dey, T.K.; Banerjee, P.; Chatterjee, R.; Dhar, P. Designing of ω-3 PUFA enriched biocompatible nanoemulsion with sesame protein
isolate as a natural surfactant: Focus on enhanced shelf-life stability and biocompatibility. Colloids Surf. A Physicochem. Eng. Asp.
2018, 538, 36–44. [CrossRef]
89. de Andrade Lima, M.; Andreou, R.; Charalampopoulos, D.; Chatzifragkou, A. Supercritical Carbon Dioxide Extraction of Phenolic
Compounds from Potato (Solanum tuberosum) Peels. Appl. Sci. 2021, 11, 3410. [CrossRef]
90. Constance, E.C.; Ifunanya, W.U.; Amarachi, M.C.E.; Idera, E.E.C.; Ikechukwu, N.; Ogechi, P.C.; Perpetua, O.C. Evaluation of
vinegar production properties of Garcina kola and Artocarpus heterophyllus. J. Appl. Chem. Sci. Internat. 2021, 12, 48–60.
91. Nguyen, T.K.; That, N.T.; Nguyen, N.T.; Nguyen, H.T. Development of starch-based bioplastic from jackfruit seed. Adv. Polymer
Technol. 2022, 26, 2022. [CrossRef]
92. Ochaikul, D.; Noiprasert, N.; Laoprasert, W.; Pookpun, S. Ethanol Production on Jackfruit Seeds by Selected Fungi and Yeast from
Loog-pang. KMITL Sci. Tech. J. 2012, 12, 1–5.
93. Miah, R.A.; Alam, M.J.; Khatun, A.; Suhag, M.H.; Kayes, M.N. The decolorization and phytotoxic efficiency of jackfruit seed on a
textile dye Novacron Blue. J. Eng. Adv. 2022, 3, 6–11. [CrossRef]
94. Abid, M.K.; Ibrahim, H.B.; Zulkifli, S.Z. Synthesis and characterization of biochar from peel and seed of jackfruit plant waste for
the adsorption of copper metal ion from water. Res. J. Pharm. Technol. 2019, 12, 4182–4188. [CrossRef]
95. Sreena, C.P.; Sebastian, D. Jackfruit outer rind: A sustainable feedstock for fermentable sugar production using recombinant
endoglucanase from Bacillus subtilis MU S1. Environ. Technol. Innov. 2019, 16, 100448. [CrossRef]
96. Sindhu, R.; Binod, P.; Pandey, A. Biological pretreatment of lignocellulosic biomass–an overview. Bioresour. Technol. 2016, 199,
76–82. [CrossRef]
97. Wang, L.; Wei, B.; Cai, F.; Chen, C.; Liu, G. Recycling durian shell and jackfruit peel via anaerobic digestion. Bioresour. Technol.
2022, 343, 126032. [CrossRef]
98. Nelluri, P.; Venkatesh, T.; Kothakota, A.; Pandiselvam, R.; Garg, R.; Eswaran, V.; Vaddevolu, U.B.P.; Venkatesh, R.;
Khaneghah, A.M. Recent advances in non-thermal and thermal processing of jackfruit (Artocarpus heterophyllus Lam): An updated
review. J. Food Process Preser. 2022, 16, e16637. [CrossRef]
99. Rahmani, A.M.; Gahlot, P.; Moustakas, K.; Kazmi, A.A.; Ojha, C.S.; Tyagi, V.K. Pretreatment methods to enhance solubilization and
anaerobic biodegradability of lignocellulosic biomass (wheat straw): Progress and challenges. Fuel 2022, 319, 123726. [CrossRef]
100. Usmani, Z.; Sharma, M.; Diwan, D.; Tripathi, M.; Whale, E.; Jayakody, L.N.; Moreau, B.; Thakur, V.K.; Tuohy, M.; Gupta, V.K.
Valorization of sugar beet pulp to value-added products: A review. Bioresour. Technol. 2022, 16, 126580. [CrossRef]
101. Sreeletha, A.S.; Lini, J.J.; Dhanyalekshmi, C.S.; Sabu, K.R.; Pratap, C.R. Phytochemical, proximate, antimicrobial, antioxidant and
FTIR analyses of seeds of Artocarpus heterophyllus Lam. Adv. Biotechnol. Microbiol. 2017, 5, 555–653.
102. Burci, L.M.; da Silva, C.B.; de Oliveira, M.; Dalarmi, L.; Zanin, S.M.W.; Miguel, O.G.; Miguel, M.D. Determination of antioxidant,
radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfruit) seeds extracts. J. Med. Plants Res.
2015, 9, 1013–1020.
103. Jiang, T.T.; Liang, Y.; Zhou, X.; Shi, Z.W.; Xin, Z.J. Optimization of a pretreatment and hydrolysis process for the efficient recovery
of recycled sugars and unknown compounds from agricultural sweet sorghum bagasse stem pith solid waste. PeerJ. 2019, 6, e6186.
[CrossRef]
104. Jaheri, M.E.; Salimi, E.; Saragas, K.; Novakovic, J.; Barampouti, E.M.; Mai, S.; Malamis, D.; Moustakas, K.; Loizidou, M. Effect of
pretreatment techniques on enzymatic hydrolysis of food waste. Biomass Conv. Bioref. 2021, 11, 219–226. [CrossRef]
105. Adewuyi, Y.G.; Deshmane, V.G. Intensification of enzymatic hydrolysis of cellulose using high-frequency ultrasound: An investi-
gation of the effects of process parameters on glucose yield. Energy Fuels 2015, 29, 4998–5006. [CrossRef]
106. Surh, J.; Decker, E.A.; McClements, D.J. Utilisation of spontaneous emulsification to fabricate lutein-loaded nanoemulsion-based
delivery systems: Factors influencing particle size and colour. Int. J. Food Sci. Technol. 2017, 52, 1408–1416. [CrossRef]
107. Aisyah, N.I.; Sundari, C.D.D.; Sunarya, R.R.; Suryaningsih, S. Optimization of bioethanol production from jackfruit straw waste
through the addition of a starter and fermentation duration. AIP Conf. Proceed 2023, 2572, 030014. [CrossRef]
108. Arif, A.R.; Natsir, H.; Rohani, H.; Karim, A. Effect of pH fermentation on production bioethanol from jackfruit seeds (Artocarpus
heterophyllus) through separate fermentation hydrolysis method. IOP Conf. Series J. Physics Conf. Seri. 2018, 979, 012015. [CrossRef]
Sustainability 2023, 15, 12520 29 of 30
109. Nikolić, S.; Lazić, V.; Veljović, Ð.; Mojović, L. Production of bioethanol from pre-treated cotton fabrics and waste cotton materials.
Carbohydr. Polym. 2017, 164, 136–144. [CrossRef]
110. Brexó, R.P.; Sant’Ana, A.S. Impact and significance of microbial contamination during fermentation for bioethanol production.
Renew. Sustain. Energy Rev. 2017, 73, 423–443. [CrossRef]
111. Yuvarani, M.; Dhas, C.S. Synthesis of Bioethanol from Artocarpus Heterophyllus Peel by Fermentation using Saccharomyces
Cerevisiae at Low Cost. GRD J. Eng. 2017, 2, 1–7.
112. Hossain, Z.; Golam, F.; Jaya, N.; Mohd, S.; Rosli, H.; Amru, N. Bioethanol Production from Fermentable Sugar Juice. Scient. World
J. 2014, 2014, 957102. [CrossRef]
113. Kaewchana, A.; Techaparin, A.; Boonchot, N.; Thanonkeo, P.; Klanrit, P. Improved high-temperature ethanol production from
sweet sorghum juice using Zymomonas mobilis overexpressing groESL genes. Appl. Microbiol. Biotechnol. 2021, 105, 9419–9431.
[CrossRef]
114. Rukshika, S.; Sisira, K.; Sanath, R.; Subramanium, S. Isolation and Characterization of an Ethanol Resistant Bacterium from Sap of
Saccharum officinarum for Efficient Fermentation. Int. J. Biotechnol. Bioeng. 2016, 3, 15–20.
115. Kularathne, I.W.; Gunathilaka, C.A.; Ratnaweera, A.C.; Kalpage, C.S.; Rajapakse, S.; Gamage, P. Optimization of Fermentation
Process Parameters for Bioethanol Production from Sri Lankan Overripe Fruits. Engineer-Liv 2021, 1, 77–86. [CrossRef]
116. Mibulo, T.; Nsubuga, D.; Kabenge, I.; Kiggundu, N.; Wydra, K.D. Comparative Study of Biogas Production from Jackfruit Waste,
Banana Peels, and Pineapple Peels Co- Digested with Cow Dung. J. Sustain. Bioenergy Syst. 2023, 13, 1–15. [CrossRef]
117. Balamaze, J.; Muyonga, J.H.; Byaruhanga, Y.B. Production and Utilization of Jackfruit (Artocarpus heterophyllus) in Uganda. Afr. J.
Food Agricult. Nutrit. Develop. 2019, 19, 14289–14302. [CrossRef]
118. Bijarchiyan, M.; Sahebi, H.; Mirzamohammadi, S. A Sustainable Biomass Network Design Model for Bioenergy Production by
Anaerobic Digestion Technology: Using Agricultural Residues and Livestock Manure. Energy Sustain. Soc. 2020, 10, 19. [CrossRef]
119. D’Adamo, I.; Falcone, P.M.; Huisingh, D.; Morone, P. A Circular Economy Model Based on Biomethane: What Are the Opportuni-
ties for the Municipality of Rome and Beyond? Renew. Energy 2021, 163, 1660–1672. [CrossRef]
120. Waluyo, J.; Pratiwi, Y. Analysis Proximate, Ultimate, and Thermal Gravimetric Based on Variations Dimensions of Briquettes
from Waste Jackfruit Crust. Int. J. Scient. Eng. Sci. 2018, 2, 36–39.
121. Walsh, J.; Jiones, D.L.; Chadwick, D.R.; Williams, A.P. Repeated application of anaerobic digestate, undigested cattle slurry and
inorganic fertilizer N: Impact on pasture yield and quality. Grass Forag. Sci. 2018, 73, 758–763. [CrossRef]
122. Westerholm, M.; Castillo, M.D.P.; Chan Andersson, A.; Jahre Nilsen, P.; Schnürer, A. Effects of thermal hydrolytic pre-treatment
on biogas process efficiency and microbial community structure in industrial- and laboratory-scale digesters. Waste Manag. 2019,
95, 150–160. [CrossRef] [PubMed]
123. Zakaria, M.R.; Ariffin, H.; Abd-Aziz, S.; Hassan, M.A.; Shirai, Y. Improved properties of poly (3-hydroxybutyrate-co-3-
hydroxyvalerate) produced by Comamonas sp. EB172 utilizing volatile fatty acids by regulating the nitrogen source. Biomed. Res.
Int. 2013, 2013, 237206. [CrossRef] [PubMed]
124. Gowda, V.; Shivakumar, S. Agrowaste-based Polyhydroxyalkanoate (PHA) Production using Hydrolytic Potential of Bacillus
thuringiensis IAM 12077. Braz. Arch. Biol. Technol. 2014, 57, 55–61. [CrossRef]
125. Sehgal, R.; Gupta, R. Polyhydroxyalkanoate and its efficient production: An eco-friendly approach towards development.
3 Biotech. 2020, 10, 549. [CrossRef]
126. Gupta, R.; Gupta, S.K.; Gehlot, C.L.; Bahadur, I. Chemically modified jackfruit leaves as a low-cost agro-waste adsorbent for
Pb(II) removal from synthetic wastewater. J. Hazardous Materi Adv. 2023, 10, 100292. [CrossRef]
127. Vardhan, K.H.; Kumar, P.S.; Pand, R.C. A review on heavy metal pollution, toxicity and remedial measures: Current trends and
future perspectives. J. Mol. Liq. 2019, 290, 111197. [CrossRef]
128. Khan, A.U. A Review on Importance of Artocarpus heterophyllus L. (Jackfruit). J. Multidiscip. Appl. Nat. Sci. 2021, 1, 106–116.
[CrossRef]
129. Zhang, L.; Lu, S.; Xiao, D.; Gu, M. Characterization of full pore size distribution and its significance to macroscopic physical
parameters in tight glutenites. J. Nat. Gas. Sci. Eng. 2017, 38, 434–449. [CrossRef]
130. Singh, A.K.; Pal, P.; Rathore, S.S.; Sahoo, U.K.; Sarangi, P.K.; Prus, P.; Dziekański, P. Sustainable Utilization of Biowaste Resources
for Biogas Production to Meet Rural Bioenergy Requirements. Energies 2023, 16, 5409. [CrossRef]
131. Sarangi, P.K.; Nanda, S. Biohydrogen production through dark fermentation. Chem. Eng. Technol. 2020, 43, 601–612. [CrossRef]
132. Sarangi, P.K.; Nayak, M.M. Agro-waste for Second Generation Biofuels. In Liquid Biofuels: Fundamentals, Characterization, and
Applications; Shadangi, K.P., Ed.; Wiley-Scrivener, Scrivener Publishing LLC: Beverly, MA, USA, 2021; pp. 697–706.
133. Sarangi, P.K.; Nanda, S.; Vo, D.V.N. Technological Advancements in the Production and Application of Biomethanol. In Biorefinery
of Alternative Resources: Targeting Green Fuels and Platform Chemicals; Nanda, S., Vo, D.V.N., Sarangi, P.K., Eds.; Springer Nature:
Boston, MA, USA, 2020; pp. 127–140.
134. Sarangi, P.K.; Nanda, S. Recent advances in consolidated bioprocessing for microbe-assisted biofuel production. In Fuel Processing
and Energy Utilization; Nanda, S., Sarangi, P.K., Vo, D.V.N., Eds.; CRC Press: Boca Raton, FL, USA, 2019; pp. 141–157.
135. Yadav, S.; Singh, D.; Mohanty, P.; Sarangi, P.K. Biochemical and Thermochemical Routes of H2 Production from Food Waste:
A Comparative Review. Chem. Eng. Technol. 2021, 46, 191–203. [CrossRef]
Sustainability 2023, 15, 12520 30 of 30
136. Sarangi, P.K.; Subudhi, S.; Bhatia, L.; Saha, K.; Mudgil, D.; Prasad, K.; Shadangi; Srivastava, R.K.; Pattnaik, B.; Arya, R.K.
Utilization of agricultural waste biomass and recycling toward circular bioeconomy. Environ. Sci. Pollut. Res. 2022, 30, 8526–8539.
[CrossRef]
137. Sarangi, P.K.; Singh, T.A.; Singh, N.J.; Shadangi, K.P.; Srivastava, R.K.; Singh, A.K.; Chandel, A.K.; Pareek, N.; Vivekanand,
V. Sustainable utilization of pineapple wastes for production of bioenergy, biochemicals and value-added products: A review.
Bioresour. Technol. 2022, 351, 127085. [CrossRef]
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