Integrity • Professionalism • Commitment • Competence • Openness • Teamwork •

Patriotism
Max Y. Suniel St, Cagayan de Oro, 9000 Misamis Oriental
Email: [email protected] +63 (088) 858-3880 / +63 917-376-5105

Name: _______________________________________________________ RLE Group/Section: _________ Hospital Area: ______________

Clinical Instructor: _____________________________________________

DRUG STUDY
TOTAL OF 30 POINTS

Drug Name Route/ Indication Mechanisms of Contraindication Side Effects Adverse Effects Nursing
Frequency/ Amlodipine may be used alone or in
Action Cardiovascular:
Responsibilities/Patient
combination with other
Amlodipine is considered a
Arrhythmia (eg, Teaching
Generic Name:
Dosage antihypertensive and antianginal Hypersensitivity to ventricular tachycardia,
agents for the treatment of the
peripheral arterial vasodilator headache, atrial fibrillation),
Amlodipine that exerts its action directly on
5mg/tab following conditions Label:
vascular smooth muscle to lead amlodipine or its bradycardia, chest pain,
components. Hepatic swelling peripheral ischemia,
Brand Name: to a reduction in peripheral
impairment, aortic stenosis, syncope, tachycardia, Before: Obtain
P.O vascular resistance, causing a (edema) of the
Norvasc, • Hypertension decrease in blood pressure. hypertrophic vasculitis patient’s history to
cardiomyopathy with ankles or feet,
Katerzia, ODHS Amlodipine is a
outflow tract obstruction. Central and peripheral allergy of amlodipine
dihydropyridine calcium nervous system:
Norliqva antagonist (calcium ion dizziness,
• Coronary artery disease antagonist or slow-channel
Hypoesthesia, • Assess vital signs
neuropathy peripheral,
blocker) that inhibits the influx lightheadednes paresthesia, tremor, before therapy
of calcium ions into both
s, vertigo
• Chronic stable angina vascular smooth muscle and DURING: • Monitor
cardiac muscle. Experimental Gastrointestinal:
studies imply that amlodipine drowsiness, Anorexia, constipation,
binds to both dihydropyridine dysphagia, diarrhea,
Patient’s BP and
• Vasospastic angina (Prinzmetal’s and nondihydropyridine tired feeling, flatulence, pancreatitis, cardiac rhythm
or Variant angina) binding sites, located on cell vomiting, gingival
membranes. The contraction of
Cardiac muscle and vascular
abdominal or hyperplasia • Monitor intake and
smooth muscle are dependent stomach pain, General: Allergic output.
• Angiographic ally documented reaction, asthenia, back
on the movement of
coronary artery disease in patients or pain, hot flushes,
without heart failure or an ejection
extracellular calcium ions into After: Monitor vital
these cells by specific ion malaise, pain, rigors,
fraction < 40%
channels. Amlodipine blocks flushing weight gain, weight signs for therapeutic
calcium ion influx across cell decrease effectiveness
membranes with selectivity.
(warmth,
redness, or Musculoskeletal system:
A stronger effect of amlodipine Arthralgia, arthrosis, • Be alert for adverse
tingly feeling). muscle cramps, myalgia
is exerted on vascular smooth effect
muscle cells than on cardiac
muscle cells Label. Direct
actions of amlodipine on
 Integrity • Professionalism • Commitment • Competence • Openness • Teamwork •
Patriotism
Max Y. Suniel St, Cagayan de Oro, 9000 Misamis Oriental
Email: [email protected] +63 (088) 858-3880 / +63 917-376-5105
vascular smooth muscle result Psychiatric: Sexual
in reduced blood pressure. dysfunction (male and
female), insomnia,
nervousness,
depression, abnormal
dreams, anxiety,
depersonalization

Respiratory system:
dyspnea, epistaxis

Skin and appendages:

Angioedema, erythema
multiforme, pruritus,
rash, rash
erythematous, rash
maculopapular

Special senses:
Abnormal vision,
conjunctivitis, diplopia,
eye pain, tinnitus

Urinary system:
Micturition frequency,
micturition disorder,
nocturia

Autonomic nervous
system: Dry mouth,
sweating increased

Metabolic and
nutritional:
hyperglycemia, thirst

Hemopoietic:
leukopenia, purpura,
Integrity • Professionalism • Commitment • Competence • Openness • Teamwork •
Patriotism
Max Y. Suniel St, Cagayan de Oro, 9000 Misamis Oriental
Email: [email protected] +63 (088) 858-3880 / +63 917-376-5105
thrombocytopenia
Integrity • Professionalism • Commitment • Competence • Openness • Teamwork •
Patriotism
Max Y. Suniel St, Cagayan de Oro, 9000 Misamis Oriental
Email: [email protected] +63 (088) 858-3880 / +63 917-376-5105