DNA Codon Alphabet
DNA Codon Alphabet
DNA contains the information that is needed by your body to make proteins. The different proteins have
specific functions, such as making our hearts, hair, eyes and ears. The smallest part of proteins are amino
acids. There are 20 amino acids. One or more can make up a protein, depending on the specific protein.
Each amino acid is represented by at least one codon. Because each codon is coded with three letters, the
string of letters used to represent the amino acids in a specific protein can get pretty long. To avoid this,
scientists have made a kind of shorthand, and have given each amino acid its own letter, corresponding to
our alphabet.
Using this shorthand to represent the amino acids in a protein is a way of describing, or “spelling” this
part of the protein. Written in this shorthand, the code is called the DNA Alias; each letter in the DNA Alias
actually represents a group of three letters (a codon).
When scientists see the DNA Alias of a particular protein, they can find the protein’s DNA sequence by
reversing the coding process. For fun, we can perform the same process on any word by converting each
letter to the corresponding codon, and in so doing, find its “DNA sequence”. Let’s try it with your name.
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Use the table on page 2 to help you convert your name into its DNA Alias.
Step 1: Find each letter of your name.
Step 2: Look at the Codon column to find the DNA code for each letter.
Step 3: Replace each letter of your name with its three-letter codon:
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DNA Detectives
What is your DNA Alias? 2
Our Alphabet Amino Acid Name Simplified Codon
A Alanine GCT
B GCA (Alanine)
C Cysteine TGC
D Aspartic acid GAT
E Glutamic acid GAG
F Phenylalanine TTT
G Glycine GGG
H Histidine CAT
I Isoleucine ATA
J ATC (Isoleucine)
K Lysine AAG
L Leucine CTC
M Methionine ATG
N Asparagine GAC
O GAT (Asparagine)
P Proline CCC
Q Glutamine GAG
R Arginine CGT
S Serine TCA
T Threonine ACT
U ACG (Threonine)
V Valine GTC
W Tryptophan TGG
X GTA (Valine)
Y Tyrosine TAC
Z TAT (Tyrosine)
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