Arterial Blood Gases: Dr. Mohamed Abbass Consultant Nephrology PGDD, Cardiff, Uk

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Nephro-Medical Tube

Arterial Blood Gases

Dr. Mohamed Abbass


Consultant Nephrology
PGDD,CARDIFF,UK
Normal value of ABG
Arterial Venous

PH 7.35-7.45 7.32-7.43
(7.40)
PaCO2 35–45 (40) 40 – 50 mmHg
PaO2 >80 mmHg 25 – 40 mmHg
HCO3a - (MEq/l) 22-26mmol/L (24) 23 – 27 mmol/L
Base excess ± 2 mmol/L ± 2 mmol/L
O2 saturation >95 % 30-40 %
H+ 37−43 nEq/L 42−48 nEq/L
Steps of interpretation of ABG ( 4

STEPS )
1.Authentic
2.Acid or Alkalosis
3.Compensation
4.Metabolic or Respiratory pathway
 Metabolic pathway:
 A,B,C,D,E
STEP 1: Authentic
 STEP3 : Compensation
 STEP3 : Compensation
 STEP3 : Compensation
 STEP3 : Compensation
 STEP 4 : Metabolic or Respiratory pathway
 Metabolic Pathway
 Metabolic Pathway
 Metabolic Pathway
5. Electrolytes, urinary:
 To determine the causes of Metabolic acidosis
o Measure the urinary anion gap (UAG) is relevant in
hyperchloremic metabolic acidosis. UAG = [Na+] +
[K+] – [Cl -]
 Negative UAG: bowel loss of bicarbonate
 Positive UAG: renal loss of bicarbonate
 To determine the causes of Metabolic alkalosis
o
 Respiratory Pathway : O-1-2-3-4-5
 Oxygenation, assessment of: PaO2/FIO2 ratio is the ratio of
arterial oxygen partial pressure to fractional alveolar oxygen,
clinical indicator of hypoxaemia
 Acute Respiratory acidosis:
Expected HCO3 =24+(PCO2-40/10 )X 1
 Chronic Respiratory acidosis:
Expected HCO3 =24+(PCO2-40/10 )X 2
 Acute Respiratory alkalosis:
Expected HCO3 =24-(40-PCO2/10) X 4
 Chronic Respiratory alkalosis:
 pH 7.18
 PCO2 58 mm Hg
 HCO3 26 mEq/L
 Respiratory acidosis (acute) due to no renal compensation.
 Expected HCO3 =24+(PCO2-40/10 )X 1= 25.5
 pH 7.39
 PCO2 52 mm Hg
 HCO3 29 mEq/L.
 Respiratory acidosis (chronic) with renal compensation.
 Expected HCO3 =24+(PCO2-40/10 )X 2= 26.4
 pH 7.57
 PCO2 25 mm Hg
 HCO3 23 mEq/L
 Respiratory alkalosis (acute) due to no renal compensation.
 Expected HCO3 =24-(40-PCO2/10) X 4= 18
 pH 7.44
 PCO2 24 mm Hg
 HCO3 16 mEq/L
 Respiratory alkalosis (chronic) with renal compensation.
 Expected HCO3 =24-(40-PCO2/10) X 5=
 Ph 7.50 (7.35–7.45)
 PCO2 28.1 mmHg (35–45)
 HCO3 23.9 mmol/L (22–28)
 Acute (uncompensated) respiratory alkalosis
 Excepted HCO3= 24-(40-PCO2/10) X 4= 19.16
 Ph 7.35 (7.35–7.45)
 PCO2 54.8 mmHg (35–45)
 HCO3 29 mmol/L (22–28)
 Chronic (compensated) primary respiratory acidosis
 Expected HCO3 =24+(PCO2-40/10 )X 2= 26.96

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