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    The document discusses pulp regeneration as the ultimate goal of regenerative endodontics. Regenerative endodontics uses tissue engineering concepts to treat necrotic immature permanent teeth, resulting in continued root development, thicker dentinal walls, and apical closure. The goal is to regenerate pulp tissue that fills the pulp chamber and root canal. This would eliminate sites for bacterial biofilms and regenerate a healthy apical tissue with dentin, cementum, periodontal ligament and bone - restoring the tooth's attachment apparatus and nerve/blood vessel tissue. Regenerating a dentin bridge closes the open apex and stops any infection, restoring the root canals to a healthy state. This development could help retain

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    Referensi 1

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    The document discusses pulp regeneration as the ultimate goal of regenerative endodontics. Regenerative endodontics uses tissue engineering concepts to treat necrotic immature permanent teeth, resulting in continued root development, thicker dentinal walls, and apical closure. The goal is to regenerate pulp tissue that fills the pulp chamber and root canal. This would eliminate sites for bacterial biofilms and regenerate a healthy apical tissue with dentin, cementum, periodontal ligament and bone - restoring the tooth's attachment apparatus and nerve/blood vessel tissue. Regenerating a dentin bridge closes the open apex and stops any infection, restoring the root canals to a healthy state. This development could help retain

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    The document discusses pulp regeneration as the ultimate goal of regenerative endodontics. Regenerative endodontics uses tissue engineering concepts to treat necrotic immature permanent teeth, resulting in continued root development, thicker dentinal walls, and apical closure. The goal is to regenerate pulp tissue that fills the pulp chamber and root canal. This would eliminate sites for bacterial biofilms and regenerate a healthy apical tissue with dentin, cementum, periodontal ligament and bone - restoring the tooth's attachment apparatus and nerve/blood vessel tissue. Regenerating a dentin bridge closes the open apex and stops any infection, restoring the root canals to a healthy state. This development could help retain

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    26 views2 pages

    Referensi 1

    Uploaded by

    andi rangga
    The document discusses pulp regeneration as the ultimate goal of regenerative endodontics. Regenerative endodontics uses tissue engineering concepts to treat necrotic immature permanent teeth, resulting in continued root development, thicker dentinal walls, and apical closure. The goal is to regenerate pulp tissue that fills the pulp chamber and root canal. This would eliminate sites for bacterial biofilms and regenerate a healthy apical tissue with dentin, cementum, periodontal ligament and bone - restoring the tooth's attachment apparatus and nerve/blood vessel tissue. Regenerating a dentin bridge closes the open apex and stops any infection, restoring the root canals to a healthy state. This development could help retain

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    Editorial

    iMedPub Journals 2016


    Journal of Orthodontics & Endodontics
    http://journals.imedpub.com ISSN 2469-2980 Vol. 3 No. 1: 1

    DOI: 10.21767/2469-2980.100035

    Pulp Regeneration: The Ultimate Goal of Maha MF Mounir


    Regenerative Endodontics Department of Oral Diagnostic Science,
    King Abdulaziz University, Kingdom of Saudi
    Arabia
    Keywords: Pulp regeneration; Endodontics; Dental pulp; Root canal

    Received: December 21, 2016; Accepted: December 26, 2016; Published: December Corresponding author: Maha MF Mounir
    30, 2016
    [email protected]

    The dental pulp, this sophisticated tissue protected inside the Professor of Oral Biology, Department of
    tooth dentin, when is destroyed or dead causes a great deal Oral Diagnostic Science, Faculty of Dentistry,
    of pain and suffering to the patient. The only viable treatment King Abdulaziz University, Jeddah, Kingdom
    is either root canal treatment RCT or extraction. To eliminate of Saudi Arabia.
    infection and protect the decontaminated tooth from further
    deterioration, root canal treatment RCT is performed. Tel: 00966555707604
    The conventional means of RCT means removing the pulp and
    packing the chamber with a plastic material. Regenerative
    endodontics uses the concept of tissue engineering to deliver
    Citation: Mounir MMF. Pulp Regeneration:
    biologically based regenerative endodontic treatment of
    The Ultimate Goal of Regenerative
    necrotic immature permanent teeth resulting in continued root
    Endodontics. J Orthod Endod. 2016, 3:1.
    development, increased thickness in the dentinal walls and apical
    closure. The ultimate goal of regenerative endodontics is pulp
    regeneration.
    The regenerated pulp tissue that fills the pulp chamber and root
    Recombinant amelogenin protein can provide signals that regulate
    gene expression and modify the inflammatory response, as well canal eliminates sites that can harbor even minimally active
    as advance the repair mechanisms of odontoblasts. Mounir et al. biofilms that can form in root canal treated teeth. Biofilms can
    [1] have developed a technology to use recombinant amelogenin contain many different types of microorganism, such as bacteria
    protein to recruit the regenerative capacity of the patient, that causes infection. A healthy apical tissue is regenerated
    resulting in the regeneration of a complete pulp. The regenerated forming the tooth attachment apparatus made of dentin,
    pulp is predicted to function identically to the one destroyed cementum, periodontal ligament (PDL) and bone. This tissue
    by disease thus transforming the tooth to a disease free state. is the hole that allows the nerve tissue, with its accompanying
    This material closes the opened apex with a regenerated dentin blood vessels, to enter the tooth by regenerating a dent in bridge
    bridge. The treated teeth show a regenerated complete dental and stops any infection that is present restoring the root canals to
    pulp, and in turn, revitalize a dead tooth with all the nerves, a healthy state. This development in regeneration of a functional
    blood vessels restoring tooth function eliminating any possibility
    pulp-dentin complex will have a promising impact on efforts to
    of infection thus the tooth is less subject to material failure as is
    the case for RCT treated teeth. retain the natural dentition.

    © Under License of Creative Commons Attribution 3.0 License | This Article is Available in: http://orthodontics-endodontics.imedpub.com 1
    ARCHIVOS
    Journal of Orthodontics DE MEDICINA
    & Endodontics 2016
    ISSN
    ISSN 1698-9465
    2469-2980 Vol. 3 No. 1: 1

    Reference
    1 Mounir MMF, Matar MA, Lei Y, Snead ML (2016) Recombinant
    amelogenin protein induces apical closure and pulp regeneration in
    open-apex, non-vital permanent canine teeth. J Endod 42: 402-412.

    2 This article is available in http://orthodontics-endodontics.imedpub.com

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