CR-101 Crystallizer DC-101 Distillation Column D-101 Dryer F-101 Centrifuge FR-101 Main Fermenter CV-101 Conveyor

EX-101 Extractor H-101 Heater H-102 Heater S-101 Seed Fermenter CP-101 Compressor P-101 Pump
P-102 Pump P-103 Pump P-104 Pump P-105 Pump P-106 Pump P-107 Pump
P-108 Pump P-109 Pump P-110 Pump C-101 Cooler

TITLE: PRODUCTION OF
12
ERYTHROMYCIN FROM
Buthyl P-101 STREPTOMYCES
acetate Carbon ERYTHREUS
dioxide gas
17
1

P-108 Buthyl
7 acetate LECTURERS
Water P-102 2
10 11

15
13

Soybean P-103 H-101

3 F-101 1. PROF. MADYA. TS . EN NOORHISHAM TAN KOFLI
2. PROF. MADYA . IR DR. ROSIAH ROHANI
P-107 3. DR MUHAMMAD ZULHAZIMAN MAT SALLEH
22
4. PROF. MADYA. IR. DR. SHUHAIDA HARUN
5. PROF. MADYA. IR. DR. TEOW YEIT HAAN
Dextrin P-104 6. PROF. MADYA. DR. NORLIZA ABD RAHMAN
4
EX-101 14
DC-101 Wastewater
7. DR JARINAH MOHD ALI
16

N-propanol P-110 5 9
P-106
21 23
CR-101
18
Air CP-101 8
KK6
P-109 CV-101
19 C-101 Erythromycin GROUP MEMBERS
D-101
20

FR-101 H-102
S-101
Glycerol medium 6
P-105

1. AHMAD SYAUQI
Fermentation
broth
AIMAN BIN ABU
BAKAR (A181693)
2. VISHNU A/L
Biomass I.SUREASH (A181364)
3. VISHNUDEVAN A/L
KAMAYA (A181366)
4. SALIHIN BIN SALMAN
(A180514)
5. ROFI AZIZANI
Stream 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 (A198018)
Phase L L L L G L G L L L L L L L L L L S/L S/L S/L S/L L S/L
pH 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7
Temperature (°C) 34 32 32 32 34 34 34 34 34 34 60 34 34 34 34 34 34 20 34 34 100 100 30
Pressure (bar) 1.3 1.3 1.3 1.3 1.3 1 1 1.3 1 1 1 1.3 1 1.2 1.2 1 1.2 1 1.2 1.2 1 1 1 KEY
Oxygen (kg/h) 0 0 0 0 1750.33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Water (kg/h) 87103.97 0 0 0 0 87103.97 0 87103.97 34841.59 52262.38 52262.38 0 1045.25 51217.13 1045.25 785.25 260 785.25 785.25 785.25 7.85 777.4 7.85
Soybean oil (kg/h) 0 199.52 0 0 0 45.35 0 45.35 0 45.35 45.35 0 0 45.35 0 0 0 0 0 0 0 0 0
Stream
Dextran (kg/h) 0 0 589.49 0 0 126.97 0 126.97 0 126.97 126.97 0 0 126.97 0 0 0 0 0 0 0 0 0 Input Number
N-propanol (kg/h) 0 0 0 1088.3 0 1088.3 0 1088.3 0 1088.3 1088.3 0 0 1088.3 0 0 0 0 0 0 0 0 0
Biomass (kg/h) 0 0 0 0 0 188.64 0 188.64 188.64 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Output
Erythromycin (kg/h) 0 0 0 0 0 372 0 372 0 372 372 0 372 0 372 372 0 372 372 372 372 0 372
Buthyl acetate (kg/h) 0 0 0 0 0 0 0 0 0 0 0 60 49 11 49 0 49 0 0 0 0 0 0
Carbon dioxide (kg/h) 0 0 0 0 0 0 308.35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Total flowrate (kg/h) 87103.97 199.52 589.49 1088.3 1750.33 88925.23 308.35 88925.23 35030.23 53895 53895 60 1466.25 52488.75 1466.25 1157.25 309 1157.25 1157.25 1157.25 379.85 777.4 379.85
 12

TT
04

TC 13
04

P-104
11

FT
04
14
FC
04
E-101

1
P-103

4
10 TC TT
steam in 02 02 18
11

TT
03
Cooling Cooling
water in water out Cooling water out
TC
TC TT
03
01 01 H-104 Cooling
water out
FT
5 Cooling
V-14 03
water in

C-101
19
FR-101
pHC FC
01 6 03

pHT
01