Scribd
Upload
55 views12 pages

PHASER

This document describes PHASER, a platform for clinical translation of FLASH cancer radiotherapy. PHASER utilizes several core technologies including the DRAGON accelerator structure, RAPiD RF power sources and distribution network, and SPHINX x-ray intensity modulation. These technologies allow for extreme beam output speeds without mechanical motion and enable fast, high-quality volumetric imaging. PHASER's beamline geometry allows for simultaneous imaging and treatment at a common isocenter. The conclusions discuss how PHASER's design is compact, power efficient, and economical while enabling future possibilities like adaptive planning, diagnostic quality CT, and automation through machine learning.

Uploaded by

Andres Leiva Genre
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
55 views12 pages

PHASER

This document describes PHASER, a platform for clinical translation of FLASH cancer radiotherapy. PHASER utilizes several core technologies including the DRAGON accelerator structure, RAPiD RF power sources and distribution network, and SPHINX x-ray intensity modulation. These technologies allow for extreme beam output speeds without mechanical motion and enable fast, high-quality volumetric imaging. PHASER's beamline geometry allows for simultaneous imaging and treatment at a common isocenter. The conclusions discuss how PHASER's design is compact, power efficient, and economical while enabling future possibilities like adaptive planning, diagnostic quality CT, and automation through machine learning.

Uploaded by

Andres Leiva Genre
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 12

PHASER: A platform for clinical

translation of FLASH cancer


radiotherapy
RADIOTHERAPY 13/12/2022
JULIETTE THARIAT

ANDRÉS LEIVA GENRE


OVERVIEW
RADIOTHERAPY

INTRODUCTION
CORE TECHNOLOGIES OF PHASER:
• ACCELERATOR STRUCTURE
• BEAMLINE GEOMETRY &
INTEGRATED IMAGING
• RF POWER SOURCES &
DISTRIBUTION NETWORK
• X-RAY INTENSITY MODULATION
CONCLUSION & FUTURES
2 PERSPECTIVES
INTRODUCTION
RADIOTHERAPY

FLASH effect (FE) discovered in 2014

Need of UHDR devices

Development of new accelerators and


3 technological innovations
ACHIEVING EXTREME SPEED
RADIOTHERAPY

REQUIREMENTS CONSTRAINS

▪ 300x beam output ▪ Compact (They must fit in existing


structures)
▪ Eliminate mechanical motion:
▪ Gantry ▪ Power efficient
▪ MLC ▪ Economical to facture and operate
▪ Fast, high-quality volumetric imaging

4
PHASER
PRESENTATION TITLE

ACCELERATOR STRUCTURE – DRAGON

RF POWER SOURCE & DISTRIBUTION


NETWORK – RAPiD

X-RAY INTENSITY MODULATION --


SPHINX

BEAMLINE GEOMETRY AND


5 CO RE TECHNO LO GIES INTEGRATED IMAGING
ACCELERATOR STRUCTURE -- DRAGON
RADIOTHERAPY

HIGH SHUNT IMPEDANCES →

IMPROVEMENT IN POWER
EFFICIENCY MINIMIZE LOSS TO
STRUCTURE HEATING

SINGLE RESONANCE
FREQUENCY

EASY TUNNING
6
RF POWER SOURCES AND
DISTRIBUTION NETWORK -- RAPiD
RADIOTHERAPY

Compact klystron (“klystrino”) RAPiD → Combined output of 16


~ 330 kW peak RF power klystrinos to feed array of
operating only at 60 kV stationary linac beamlines
7
PRESENTATION TITLE X-RAY INTENSITY MODULATION --
SPHINX

1. Pencil beamlet of X-rays. Intensity is controlled by the electron beam intensity


8 2. The set of beamlets can be geometrically adapted & specified
3. The spacing between beamlets is fine enough to provide total coverage of the tumor without any gaps
BEAM LINE GEOMETRY &
RADIOTHERAPY

INTEGRATED IMAGING

9
A common isocenter allows simultaneous
imaging & treatment
10
RADIOTHERAPY

PHASER
CONCLUSIONS & FUTURES
RADIOTHERAPY

PERSPECTIVES
ADAPTIVE
VHEE PHASER DESIGN
PLANNING

Compactness Diagnostic quality CT


Power efficient Automation through ML
Economical High clinical efficiency
manufacturing

11
THANK YOU

ANDRÉS LEIVA GENRE

You might also like