SAFETY DATA SHEET

1. Identification
Product identifier CIDEZYME Enzymatic Detergent
Other means of identification
SDS number 11415-US
Product number 2258, 2260
Recommended use Detergent.
Recommended restrictions Restricted to professional users.
Manufacturer/Importer/Supplier/Distributor information
Company name Advanced Sterilization Products,Inc.
Address 33 TECHNOLOGY DRIVE
IRVINE, CA 92618
Country US
Telephone number 1-888-783-7723
E-mail [email protected]

24 Hour Emergency CHEMTREC US: 1-800-424-9300 CCN 795874

Telephone
CHEMTREC International: +1 703-741-5970

2. Hazard(s) identification
Physical hazards Not classified.

Health hazards Sensitization, respiratory Category 1

OSHA defined hazards Not classified.

Label elements

Signal word Danger

Hazard statement May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statement
Prevention Avoid breathing mist. In case of inadequate ventilation wear respiratory protection.
Response If inhaled: If breathing is difficult, remove person to fresh air and keep comfortable for breathing. If
experiencing respiratory symptoms: Call a poison center/doctor.
Storage Store away from incompatible materials.
Disposal Dispose of waste and residues in accordance with local authority requirements.
Hazard(s) not otherwise None known.
classified (HNOC)
Supplemental information None.

3. Composition/information on ingredients
Mixtures
Chemical name CAS number %
Propane -1,2 -diol 57-55-6 10 - 20

Disodium tetraborate 1303-96-4 1-<3

decahydrate

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 Subtilisin 9014-01-1 0.1 - < 1

Composition comments All concentrations are in percent by weight unless ingredient is a gas. Gas concentrations are in
percent by volume. Components not listed are either non-hazardous or are below reportable limits.

4. First-aid measures
Inhalation In case of inhalation: If breathing is difficult, remove to fresh air and keep at rest in a position
comfortable for breathing. Oxygen or artificial respiration if needed. Do not use mouth-to-mouth
method if victim inhaled the substance. Induce artificial respiration with the aid of a pocket mask
equipped with a one-way valve or other proper respiratory medical device. If experiencing
respiratory symptoms: Call a poison center or doctor/physician.
Skin contact Wash off with soap and water. Get medical attention if irritation develops and persists.
Eye contact Rinse with water. Get medical attention if irritation develops and persists.
Ingestion Rinse mouth. Get medical attention if symptoms occur.
Most important Exposure may cause temporary irritation, redness, or discomfort. Sensitization.
symptoms/effects, acute and
delayed
Indication of immediate Provide general supportive measures and treat symptomatically. Keep victim under observation.
medical attention and special Symptoms may be delayed.
treatment needed
General information If you feel unwell, seek medical advice (show the label where possible). Ensure that medical
personnel are aware of the material(s) involved, and take precautions to protect themselves. Show
this safety data sheet to the doctor in attendance.

5. Fire-fighting measures
Suitable extinguishing media Use extinguishing agent suitable for type of surrounding fire.
Unsuitable extinguishing Do not use water jet as an extinguisher, as this will spread the fire.
media
Specific hazards arising from During fire, gases hazardous to health may be formed.
the chemical
Special protective equipment Self-contained breathing apparatus and full protective clothing must be worn in case of fire.
and precautions for firefighters
Fire fighting Move containers from fire area if you can do so without risk.
equipment/instructions
Specific methods Use standard firefighting procedures and consider the hazards of other involved materials.
General fire hazards No unusual fire or explosion hazards noted.

6. Accidental release measures

Personal precautions, Keep unnecessary personnel away. Keep people away from and upwind of spill/leak. Wear
protective equipment and appropriate protective equipment and clothing during clean-up. Avoid breathing mist. Ensure
emergency procedures adequate ventilation. Local authorities should be advised if significant spillages cannot be
contained. For personal protection, see section 8 of the SDS.
Methods and materials for Large Spills: Stop the flow of material, if this is without risk. Dike the spilled material, where this is
containment and cleaning up possible. Absorb in vermiculite, dry sand or earth and place into containers. Following product
recovery, flush area with water.

Small Spills: Wipe up with absorbent material (e.g. cloth, fleece). Clean surface thoroughly to
remove residual contamination.

Never return spills to original containers for re-use. For waste disposal, see section 13 of the SDS.
Environmental precautions Avoid discharge into drains, water courses or onto the ground.

7. Handling and storage

Precautions for safe handling Avoid breathing mist. Avoid prolonged exposure. Provide adequate ventilation. Wear appropriate
personal protective equipment. Observe good industrial hygiene practices.
Conditions for safe storage, To maintain product quality, do not store in heat or direct sunlight. Store in tightly closed container.
including any incompatibilities Store in a well-ventilated place. Store away from incompatible materials (see Section 10 of the
SDS). Store in original container. Recommended storage temperature: 15 - 30 °C.

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8. Exposure controls/personal protection
Occupational exposure limits
US. ACGIH Threshold Limit Values
Components Type Value Form

Disodium tetraborate STEL 6 mg/m3 Inhalable fraction.

decahydrate (CAS
1303-96-4)
TWA 2 mg/m3 Inhalable fraction.
Subtilisin (CAS 9014-01-1) Ceiling 0.00006 mg/m3

US. NIOSH: Pocket Guide to Chemical Hazards

Components Type Value
Disodium tetraborate TWA 5 mg/m3
decahydrate (CAS
1303-96-4)
Subtilisin (CAS 9014-01-1) STEL 0.00006 mg/m3

US. Workplace Environmental Exposure Level (WEEL) Guides

Components Type Value Form

Propane -1,2 -diol (CAS TWA 10 mg/m3 Aerosol.

57-55-6)
Biological limit values No biological exposure limits noted for the ingredient(s).
Appropriate engineering Good general ventilation should be used. Ventilation rates should be matched to conditions. If
controls applicable, use process enclosures, local exhaust ventilation, or other engineering controls to
maintain airborne levels below recommended exposure limits. If exposure limits have not been
established, maintain airborne levels to an acceptable level.
Individual protection measures, such as personal protective equipment
Eye/face protection Wear safety glasses with side shields (or goggles).

Skin protection
Hand protection Wear appropriate chemical resistant gloves. Nitrile gloves are recommended.

Skin protection
Other Wear appropriate chemical resistant clothing. Use of an impervious apron is recommended.
Respiratory protection When workers are facing concentrations above the exposure limit they must use appropriate
certified respirators. Use a positive-pressure air-supplied respirator if there is any potential for an
uncontrolled release, exposure levels are not known, or any other circumstances where
air-purifying respirators may not provide adequate protection.
Thermal hazards Wear appropriate thermal protective clothing, when necessary.

General hygiene Always observe good personal hygiene measures, such as washing after handling the material
considerations and before eating, drinking, and/or smoking. Routinely wash work clothing and protective
equipment to remove contaminants.

9. Physical and chemical properties

Appearance
Physical state Liquid.
Form Liquid.
Color Clear. Violet.
Odor Mint-like.
Odor threshold Not available.
pH 7.8 - 8.8
Melting point/freezing point Not available.
Initial boiling point and boiling Not available.
range
Flash point > 199.4 °F (> 93.0 °C)
Evaporation rate Not available.
Flammability (solid, gas) Not applicable.
CIDEZYME Enzymatic Detergent SDS US
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Upper/lower flammability or explosive limits
Flammability limit - lower Not available.
(%)
Flammability limit - upper Not available.
(%)
Vapor pressure Not available.
Vapor density Not available.
Relative density 1.09
Solubility(ies)
Solubility (water) Soluble in water.
Partition coefficient Not available.
(n-octanol/water)
Auto-ignition temperature Not available.
Decomposition temperature Not available.
Viscosity Not available.
Other information
Explosive properties Not explosive.
Oxidizing properties Not oxidizing.

10. Stability and reactivity

Reactivity The product is stable and non-reactive under normal conditions of use, storage and transport.
Chemical stability Material is stable under normal conditions.
Possibility of hazardous No dangerous reaction known under conditions of normal use.
reactions
Conditions to avoid Contact with incompatible materials. Heat, flames and sparks. Avoid frost.
Incompatible materials Strong oxidizers, strong acids, and strong bases. Reducing agents.
Hazardous decomposition Thermal decomposition of this product can generate carbon monoxide and carbon dioxide. Sulfur
products dioxide.

11. Toxicological information

Information on likely routes of exposure
Inhalation In case of inhalation: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Prolonged inhalation may be harmful.
Skin contact Prolonged skin contact may cause temporary irritation.
Eye contact Direct contact with eyes may cause temporary irritation.
Ingestion May cause discomfort if swallowed.
Symptoms related to the Exposure may cause temporary irritation, redness, or discomfort. Sensitization.
physical, chemical and
toxicological characteristics
Information on toxicological effects
Acute toxicity Not expected to be acutely toxic.
Components Species Test Results
Disodium tetraborate decahydrate (CAS 1303-96-4)
Acute
Dermal
LD50 Rabbit > 2000 mg/kg, 24 Hours
Inhalation
Dust
LC50 Rat > 2.04 mg/l, 4 Hours
Oral
LD50 Rat > 2500 mg/kg

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Components Species Test Results
Propane -1,2 -diol (CAS 57-55-6)
Acute
Dermal
LD50 Rabbit 20800 mg/kg
Oral
LD50 Rat 22000 mg/kg
Skin corrosion/irritation Prolonged skin contact may cause temporary irritation.
Serious eye damage/eye Direct contact with eyes may cause temporary irritation.
irritation
Respiratory or skin sensitization
Respiratory sensitization May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Skin sensitization This product is not expected to cause skin sensitization.
Germ cell mutagenicity No data available to indicate product or any components present at greater than 0.1% are
mutagenic or genotoxic.
Carcinogenicity Not classifiable as to carcinogenicity to humans.
IARC Monographs. Overall Evaluation of Carcinogenicity
Not listed.
NTP Report on Carcinogens
Not listed.
OSHA Specifically Regulated Substances (29 CFR 1910.1001-1053)
Not listed.
Reproductive toxicity The product contains a small amount of substance that may damage fertility or the unborn child.
Specific target organ toxicity - Not classified.
single exposure
Specific target organ toxicity - Not classified.
repeated exposure
Aspiration hazard Not an aspiration hazard.
Chronic effects Prolonged inhalation may be harmful.
Further information No data available.

12. Ecological information

Ecotoxicity The product is not classified as environmentally hazardous. However, this does not exclude the
possibility that large or frequent spills can have a harmful or damaging effect on the environment.
Components Species Test Results
Disodium tetraborate decahydrate (CAS 1303-96-4)
Acute
LC50 Limanda limanda 74 mg/l, 4 days
Aquatic
Acute
Fish LC50 Fathead minnow (Pimephales promelas) 79.7 mg/l, 4 days
Propane -1,2 -diol (CAS 57-55-6)
Aquatic
Acute
Algae EC50 Selenastrum capricornutum 19000 mg/l, 72 hours
Crustacea LC50 Ceriodaphnia 18340 mg/l, 48 hours
Fish LC50 Pimephales promelas 46500 mg/l, 96 hours
Persistence and degradability Expected to be readily biodegradable.
Bioaccumulative potential The product is not expected to bioaccumulate.
Mobility in soil No data available.
Other adverse effects No other adverse environmental effects (e.g. ozone depletion, photochemical ozone creation
potential, endocrine disruption, global warming potential) are expected from this component.

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13. Disposal considerations
Disposal instructions Collect and reclaim or dispose in sealed containers at licensed waste disposal site. Dispose of
contents/container in accordance with local/regional/national/international regulations.
Local disposal regulations Dispose in accordance with all applicable regulations.
Hazardous waste code The waste code should be assigned in discussion between the user, the producer and the waste
disposal company.
Waste from residues / unused Dispose of in accordance with local regulations. Empty containers or liners may retain some
products product residues. This material and its container must be disposed of in a safe manner.
Contaminated packaging Since emptied containers may retain product residue, follow label warnings even after container is
emptied. Empty containers should be taken to an approved waste handling site for recycling or
disposal.

14. Transport information

DOT
Not regulated as dangerous goods.
IATA
Not regulated as dangerous goods.
IMDG
Not regulated as dangerous goods.
Transport in bulk according to Not applicable.
Annex II of MARPOL 73/78 and
the IBC Code

15. Regulatory information

US federal regulations This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication
Standard, 29 CFR 1910.1200.
TSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D)
Not regulated.
CERCLA Hazardous Substance List (40 CFR 302.4)
Not listed.
SARA 304 Emergency release notification
Not regulated.
OSHA Specifically Regulated Substances (29 CFR 1910.1001-1053)
Not listed.
Toxic Substances Control Act (TSCA) All components of the mixture on the TSCA 8(b) inventory are designated
“active”.
Superfund Amendments and Reauthorization Act of 1986 (SARA)
SARA 302 Extremely hazardous substance
Not listed.
SARA 311/312 Hazardous Yes
chemical
Classified hazard Respiratory or skin sensitization
categories
SARA 313 (TRI reporting)
Not regulated.

Other federal regulations

Clean Air Act (CAA) Section 112 Hazardous Air Pollutants (HAPs) List
Not regulated.
Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR 68.130)
Not regulated.
Safe Drinking Water Act Not regulated.
(SDWA)
US state regulations
US. Massachusetts RTK - Substance List
Disodium tetraborate decahydrate (CAS 1303-96-4)

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 US. New Jersey Worker and Community Right-to-Know Act
Disodium tetraborate decahydrate (CAS 1303-96-4)
Propane -1,2 -diol (CAS 57-55-6)
US. Pennsylvania Worker and Community Right-to-Know Law
Disodium tetraborate decahydrate (CAS 1303-96-4)
Propane -1,2 -diol (CAS 57-55-6)
US. Rhode Island RTK
Disodium tetraborate decahydrate (CAS 1303-96-4)
Propane -1,2 -diol (CAS 57-55-6)
California Proposition 65
California Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65): This material
is not known to contain any chemicals currently listed as carcinogens or reproductive toxins. For
more information go to www.P65Warnings.ca.gov.
US. California. Candidate Chemicals List. Safer Consumer Products Regulations (Cal. Code Regs, tit. 22, 69502.3,
subd. (a))
Disodium tetraborate decahydrate (CAS 1303-96-4)
Subtilisin (CAS 9014-01-1)
International Inventories
Country(s) or region Inventory name On inventory (yes/no)*
Australia Australian Inventory of Chemical Substances (AICS) No
Canada Domestic Substances List (DSL) No
Canada Non-Domestic Substances List (NDSL) Yes
China Inventory of Existing Chemical Substances in China (IECSC) Yes
Europe European Inventory of Existing Commercial Chemical No
Substances (EINECS)
Europe European List of Notified Chemical Substances (ELINCS) No
Japan Inventory of Existing and New Chemical Substances (ENCS) No
Korea Existing Chemicals List (ECL) No
New Zealand New Zealand Inventory No
Philippines Philippine Inventory of Chemicals and Chemical Substances No
(PICCS)
Taiwan Taiwan Chemical Substance Inventory (TCSI) Yes
United States & Puerto Rico Toxic Substances Control Act (TSCA) Inventory Yes
*A "Yes" indicates this product complies with the inventory requirements administered by the governing country(s).
A "No" indicates that one or more components of the product are not listed or exempt from listing on the inventory administered by the governing
country(s).

16. Other information, including date of preparation or last revision

Issue date 06-February-2020
Revision date 15-April-2020
Version # 03
HMIS® ratings Health: 1*
Flammability: 0
Physical hazard: 0
List of abbreviations LD50: Lethal Dose 50%.
LC50: Lethal Concentration 50%.
EC50: Effective Concentration 50%.
References HSDB® - Hazardous Substances Data Bank
Disclaimer Advanced Sterilization Products cannot anticipate all conditions under which this information and
its product, or the products of other manufacturers in combination with its product, may be used. It
is the user’s responsibility to ensure safe conditions for handling, storage and disposal of the
product, and to assume liability for loss, injury, damage or expense due to improper use. The
information in the sheet was written based on the best knowledge and experience currently
available.

CIDEZYME Enzymatic Detergent SDS US

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