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    2nd Unit

    Uploaded by

    Ala'a Emerald Aguam
    This document contains questions about medications and their indications, mechanisms of action, and adverse effects. It includes questions about nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), medications for gout, pulmonary hypertension, and peptic ulcer disease. The questions cover topics such as cyclooxygenase isozymes, leukotriene inhibitors, prostaglandins, JAK inhibitors, and uricase.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    2nd Unit

    Uploaded by

    Ala'a Emerald Aguam
    40 views4 pages
    This document contains questions about medications and their indications, mechanisms of action, and adverse effects. It includes questions about nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), medications for gout, pulmonary hypertension, and peptic ulcer disease. The questions cover topics such as cyclooxygenase isozymes, leukotriene inhibitors, prostaglandins, JAK inhibitors, and uricase.

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    2nd-Unit

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    This document contains questions about medications and their indications, mechanisms of action, and adverse effects. It includes questions about nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), medications for gout, pulmonary hypertension, and peptic ulcer disease. The questions cover topics such as cyclooxygenase isozymes, leukotriene inhibitors, prostaglandins, JAK inhibitors, and uricase.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    40 views4 pages

    2nd Unit

    Uploaded by

    Ala'a Emerald Aguam
    This document contains questions about medications and their indications, mechanisms of action, and adverse effects. It includes questions about nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), medications for gout, pulmonary hypertension, and peptic ulcer disease. The questions cover topics such as cyclooxygenase isozymes, leukotriene inhibitors, prostaglandins, JAK inhibitors, and uricase.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 4

    2nd Unit: 2nd Bimonthly A.

    Vit c

    B. Ferrous

    1. True about prostanoid effects in the kidney C. B complex

    A. Txa2 derived prostanoids promoted vasodilation and


    improve renal function
    6. Adverse effect of drugs for treatment of pulmonary
    B. Cox1 derived prostanoids promote na reabsorption hypertension (PGI2 analogs)?

    C. Cox2 derived prostanoids inhibit na excretion in the A. Hypertension


    collecting tubules
    B. Constipation
    D. Cox2 derived prostcyclin and PGE2 promote renal
    C. Flushing
    blood flow and GFR
    D. Aota

    2. Adverse effect of allopurinol warn the patient

    A. Gout attacks 7. Cromolyn

    B. Gi intolerance

    C. Heart 8. Zileutonileuton MOA -

    Ans. lipoxygenase inhibitor

    3. Use of this medication reduces the incidence of


    gastrointestinal and liver function test abnormalities 9. Mechanism of action of zileuton -
    associated with methotrexate.
    Ans. 5-lipoxygenase inhibitor
    a. Vit C

    b. Folic acid
    10. Azithromycin
    c. Ferrous sulfate
    A. Reliever
    d. Vit B
    B. Controller

    C. A and B
    4. DMARD that is rapidly converted in the intestine and
    plasma to active metabolite A77-1726 leading to arrest D. None of the above
    of stimulated cell in the G1 phase of cell growth -

    Ans. Leflunomide
    11. Concurrent use of this reduces prevalence of
    antibodies against TNF@ blcoking agents

    5. Use of the following medication.... GI, liver abnormal A. retuximab


    methotrexate.
    B. costeroids
    C. closphorine 17. The degree of this nsaid side effects is thought to
    correlate in the amount of enterohaptic concentration?
    D. methotrexate
    A. GI irritation

    B. Nephrotoxicity
    12. Drugs useful in cases of acute gout attack
    C. Rashes
    A- Colchicine
    D. Increased liver enzymes
    B- Allopurinol

    C- Febuxostat
    18. Prior to starting him on DMRAD it is important to
    D- All of the above start IR for the ff.

    13. Patient with gout but have transaminitis. What drug A. Inflammatory bowel disease
    should be given.

    A. Diclofenac
    B. Latent TB infection
    B. Sulindac

    C. Tolmetin
    C. Malignancy
    D. Celecoxib

    D. No need to test for disease


    14. Salmeterol

    19. A COX isozyme that is expressed constitutively from


    15. Slowly progressive dyspnea.. Severe pulmonary the cells and is important in the platelet regulation,
    hypertension.. This medication is not of use in the mgt kidney function and cytoprotection
    of the patient.
    A. Cyclooxygenase 1

    B. Cyclooxygenase 2
    16. RS, 67 year old male have progressive dyspnea.
    Extensive workup revealed to have pulmonary C. Cyclooxygenase 3
    hepertension. Which is NOT used
    D. Cyclooxygenase 4
    A. Epoprostenol

    B. Iloprost
    20. Adverse effect of Alprostadil for patient to be
    C. Treprostinil watched for include:

    D. Dinoprostone A. Hypotension

    B. Hypertension
    C. Tachycardia

    D. Hyperpnea 28. this receptor is mainly "contractile" effect.

    A. Tp receptor

    21. What COX isozyme is inherent in cells and is B. Ep4 receptor


    responsible for plt aggregation, kidney fxn..?
    C. Dp1 receptor
    A. COX 1
    D. Ip receptor
    B. COX 2

    C. COX 3
    29. true of azathioprine
    D. COX 4
    Ans-acts thru its major metabolite 6-thioguanine to
    supress b and t cell function

    22. Inhibits all members of Janus Kinase (JAK) family

    Ans. Tofacitinib 30. IL-12 and IL-23 antagonists; subcutaneous injection

    ans: c. Ustekinumab

    23. Montelukast-

    Ans. Luekotriene inhibitor 31. methylxantines inhibits blah blah from mast cells by
    inhibiting blah blah by this substance.

    A. Prostaglandin
    24. aminophyline
    B. Leukotrines

    C. Forgot
    25. Used to oxidise xanthene to uric acid and used in d
    drug alloplurinol D. Forgot

    Ans - xanthane oxidase

    32. Concomitant use with this drug decreases


    antibodies against TNF a blocking agent.
    26. Terminate early pregnancy
    A. Cyclosporine

    B. Methothrexate*
    27. True of eicosanoids
    C. Corticosteroids
    A. Long acting
    D. Rituximab
    B. Non specific

    C. Reactbto singe receptor, single effects


    33.. Mr JC 35 year old. Epigastric pain. You diagnosed as
    D. Determine by type on different cells peptic ulcer disease. What is the proper treatment?
    A.

    B. Misoprostol

    C.

    D.

    34. This drug is a recombinant mammalian uricase that


    convert uric acid to allantoin -

    Ans. pegloticase

    35. Short acting B agonist

    36. Cromolyn indicated for

    A.

    B. Food

    C. Exercise induced

    D.Virus

    3rd Unit:

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