Agropages June 2021 Biologicals Special

Interviews
2021 Biologicals Special 1

Interviews Cover Story
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2021 Biologicals Special
Advertiser Index
AFEPASA P16
Agri Star S.A. P52
ASFERTGLOBAL P8
Natural
Azotic P35
BASF P4
Battelle P2
partners Beijing Kingbo Biotech Co., Ltd. P85
Beijing Multigrass Formulation Co., Ltd. Inside Front Cover
Biobest Belgium N.V. P70
Biolchim S.p.A. P11

To help meet the ever-growing demand for high
Certis Biologicals P44
quality crops grown more sustainably, we believe
Certis Europe P21
in finding the right balance between efficacy
and sustainability. Chengdu Newsun Crop Science Co., Ltd. P49
Compliance Services International (CSI) P91

Combining BioSolutions from BASF – like Serifel ,
®
Dogal Kimyevi Maddeler ve Zira Back Cover
our super-effective biological fungicide – with our P65
Scan to download it Eurofins Agroscience Services Ltd.
conventional crop protection products in what
Evonik Industries AG P62
we see as a natural partnership. Giving you greater
Fertiliser Consultants Network (FCN) P49
choice. Helping you reduce residues, manage
resistance, strengthen stress tolerance, extend the Futureco Bioscience P13
windows of disease and pest protection, and add Idai Nature P43
flexibility to harvest timings. Naturally. Ingevity P58
TEL：+86-571-87240039
Intermag Ltd. P46
EMAIL：[email protected]
BioSolutions by BASF P48
Jiangyin Milagro Chemical Co., Ltd.
Kimitec P50
Leili Marine BioIndustry INC. P21
Lim-Loges & Masters Pte Ltd. P57
Oro Agri P31
Oxiteno P54
Gold Sponsor Plant-DiTech P61
Scientific Consulting Company (SCC) P1
Sea6 Energy P18
Seipasa SA P72
Sino Agro-Chemical Industry Ltd. P69
Solvay P66
Staphyt P3
STK P73
Silver Sponsor Tradecorp Nutri-Performance P40
Zhejiang Sega Science and Technology Co., Ltd. Inside Back Cover
Disclaimer: If some advertisements and product profiles in this issue contain references to active ingredients still under patent protection in certain countries, such content are
biosolutions.basf.com
4 2021 Biologicals Special
deemed inapplicable to those countries.
CONTENTS P26 Registration Policies
The Core and Changes in Registration Regulation for Biopesticides and

Cover Story Biostimulants in Key Markets: EU, US, India and Japan
The process of Greening and Sustainability, long neglected in the EU, significantly gains momentum.
Asfertglobal Expands in International Markets with
P08 Sustainable Biofertilizers
There is a reduced data set for naturally occurring biochemical pesticides compared to other registrations.
The registration of biopesticides is governed under the Insecticides Act 1968 and handled by CIB. A regulatory body as well as
compliance requirements for the biostimulant market have been established in line with the FCO.
On 12 May 2021, MAFF released "Green Food System Strategy – Achieving both productivity improvement and sustainability
of food, agriculture, forestry and fisheries through innovation".
Asfertglobal is a leading Portuguese company in

the development of biofertilisers based on the use of P32 Biopesticide Active Ingredients Get Policy Support for Entrance into Chinese Market
microorganisms and new organic molecules from natural
sources. Asfertglobal's organic solutions have led the
international expansion to the key markets. Earlier this year,
the company announced the opening of new subsidiary abroad
in Mexico, and the first export to the Chinese market. Today, Products and Technologies
Asfertglobal’s products are present in twenty-five countries, such as
Spain, South Africa, France, USA, Italy, Greece, Turkey and Russia.
AgroPages interviewed the CEO of Asfertglobal, Joel Jerónimo, P36 Greening up the Future of Our Food Production P66 Solvay: Enhanced Adjuvants & Co-formulants Toolbox
who is leading the company to internationalization, with their biologicals for Microbial Biopesticides
recognized as efficient and sustainable for agricultural production. P38 PREV-AM® the 3-in-1 Insecticide, Fungicide and
Joel Jerónimo, CEO of Asfertglobal Miticide, Problem-solver with Minimal Environmental P70 Biobest Embraces AI to Help Growers Drive up Yields
Impact
P74 Regev™ – A Broad-Spectrum Hybrid Fungicide for
P40 Biostimulation, from Novel Technology to a Must in Disease Control
Agriculture
P12 Interviews P43 Idai Nature, France Launches PORTENTO® to

Eliminate Fungi for Good
P44 The Global Expansion of Certis Biologicals Viewpoints

Biolchim’s Way to Face Divers, Growing Challenges
P46 Fertilizers for New Challenges
Biolchim is a leading company in Italy and in the world in terms of the production and commercialization
P76 Biologicals Business Development at Bayer, UPL,
of special fertilizers, most notably biostimulants. P50 Deep Diving into Biological Dark Matter Syngenta and Sumitomo Chemical
Anna Fontana PhD Every year, AgroPages follows and interviews the product managers of Biolchim to ask them about
their new products, R&D and plans to adapt to the rapid developments occurring around the world. P78 Haifa, Nutrien, Kingenta and New Yonfer Fertilizer’s
P52 Challenges of Bio Market in Argentina; Agri Star
Adds M2i Pheromones into Package Views on the Biostimulant Industry and Market
P54 Biosolutions at OXITENO: Capabilities and P83 Russian Biostimulant Industry Watch: From Research,
P13 Futureco Bioscience, Expert in Bio-Precision Agriculture with Strong R&D&I Capacity Field Practice Points of View
Technologies for the Biopesticide Market
P16 AFEPASA: Serving Sustainable Agriculture with 128 Years of Experience in Sulphur Products
P58 Ingevity’s New Generation of Sustainable Dispersants
Meets the Complex Challenges of Biological
P18 Sea6 Energy: Creating Innovative Products in a Sustainable Way, by Combining the Strengths of Patented Ocean
Formulations
Farming System, Cutting Edge Research and Superior Agronomy Expertise
P22 Working Together to Create a 3B New Era, Establish a Balanced Agricultural Value Community
P62 Evonik BREAK-THRU® Additives Applied Tank-Side
in Field Trials to Enhance Efficacy of Biopesticides
P87 Company Directory
Cover Story Cover Story
Asfertglobal Expands in International

Markets with Sustainable Biofertilizers
Asfertglobal is a leading Portuguese company in

the development of biofertilisers based on the use of
microorganisms and new organic molecules from natural Are there any things you would like to highlight
sources. Asfertglobal's organic solutions have led the about other products developed by Asfertglobal?
international expansion to the key markets. Earlier this year,
the company announced the opening of new subsidiary abroad I would like to highlight Kiplant iNmass, also a biofertilizer
in Mexico, and the first export to the Chinese market. Today, composed of a bacterial consortium but which contains nitrogen-fixing
Asfertglobal’s products are present in twenty-five countries, such as microorganisms and phytohormone producers, whose synergy results in
Spain, South Africa, France, USA, Italy, Greece, Turkey and Russia. an effective complement of nutrition for the plant.
AgroPages interviewed the CEO of Asfertglobal, Joel Jerónimo, These solutions make it possible to reduce the amount of
who is leading the company to internationalization, with their biologicals conventional fertilizers added to the soil by around 50%, making
recognized as efficient and sustainable for agricultural production. agriculture more sustainable and more environmentally friendly.
Today we are attentive to sustainable agriculture and

Joel Jerónimo, CEO of Asfertglobal try to minimize the impact of farming on the ecosystem.
Would you like to talk about Asfertglobal's strategy for
food production with zero waste?
The European Commission aims to reduce by 50% the use of

Fast growing for over twenty years, Asfertglobal is Microbial fertilizers can significantly improve the pesticides and other chemically synthesized active ingredients while
now selling various biofertilizer products in twenty-five soil health. What are the advantages of Asfertglobal’s ensuring no deterioration of soil fertility.
countries in Europe, Africa, Americas and Asia. Could biofertilizer Kiplant AllGrip? It also intends to strengthen the development of organic farming in
you please tell us some milestones during the company’s the EU area, with the goal of achieving 25% of the total agricultural land
development? AllGrip is a biofertilizer made up of a bacterial consortium that dedicated to organic farming by 2030.
promotes plant growth, with particularly relevant action in the production In this sense, it is necessary to give more and more importance to Asfertglobal has started the business in the South
We remain committed to meeting the company's growth objectives of phytohormones, solubilization of phosphate from inorganic sources. sustainable solutions that involve the use of microorganisms, substances American. What challenges did you encounter when
and we are investing in our internationalization and in our products. Kiplant AllGrip microorganisms produce several enzymes, such of origin in natural extracts and without residues. exploring the emerging market? How did you tackle
In this sense, since last year we have reinforced internationalization as acid and alkaline Let us not doubt that the sustainability of today's agriculture lies in them?
by entering several markets, where I can highlight the Mexican market phosphatases, phytases the technological innovation that has allowed us to reach a level of food
and China, two very demanding markets, which has been possible (which hydrolyze safety never achieved before. Without a doubt, the big challenge of entering other markets are the
thanks to the strong investment in R+D made by a multidisciplinary the phytate, one of bureaucratic issues where the different markets have different regulations
team which includes biologists and agronomists who help us to practice the organic types and therefore it is necessary to be aware of all these issues.
a more sustainable agriculture, more ecological and consequent, with of Phosphorus This year, with the worldwide pandemic outlook, the biggest
zero impact on the environment. This is the secret to the growing more common in difficulties we faced was really the lack of face-to-face contact with our
confidence for these managements. vegetables tissues) and customers, producers and distributors. We tried to keep production, and
This new business framework supports our internationalization esterase related with contact with customers with the same dedication, but with a different
process, while we are reinforcing and strengthening our presence in the the degradation of format, through all the means available such as mobile phone, emails,
American market, where we already have commercial activity in the phospholipids. video conferences, among others.
USA, Chile and Peru.

Cover Story Cover Story
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Interviews Interviews
Biolchim’s Way to Face Divers,

Growing Challenges Futureco Bioscience, Expert in Bio-Precision
Anna Fontana PhD, Product Manager at Biolchim Agriculture with Strong R&D&I Capacity
Biolchim is a leading company in Italy and in the world in terms of the production and commer-
cialization of special fertilizers, most notably biostimulants.
Every year, AgroPages follows and interviews the product managers of Biolchim to ask
them about their new products, R&D and plans to adapt to the rapid developments occur-
ring around the world.
"Futureco Bioscience has always been a company which focuses on soil health
and soil microorganisms in order to boost crop production. It suffices to say that
one of our best selling products is Bioradicante. Added metabolites boost critical
With the chemical pesticide and fertilizer The awareness about the arrangement of the entire industry functionalities in our products' portfolio (as is already the case of Radisan and the
giants getting involved with the biostimulants chain is rising. What activities does Biolchim engage in to ensure the line of DEFENDERs), and with Genomaat, our metagenomic platform for microbial
industry which allegedly is warming this indus- whole industry chain works seamlessly? communities engineering, we have the tools to really transform crop production in
try, what is the attitude of Biolchim? What kind a sustainable way. I am confident that this is the beginning of what bio-precision
of cooperation opportunities exist? Biolchim has always paid a lot of attention to the industry chain, both upstream, with agriculture will be in the near future," said Rafael Juncosa, the CEO and President
the selection of raw materials and downstream, towards the growers who use our prod- of Futureco Bioscience, in this interview with AgroPages.
Biolchim continues its development path backed by ucts. For example, our seaweeds are sustainably harvested from their natural growing
more than 40 years of experience in the sector, robust environment on the Canadian coasts, our proteins hydrolysates are derived from selected
know-how, and a strong, steadily growing international raw materials from other industries according to the principles of a circular economy. Rafael Juncosa, CEO and President of Futureco Bioscience
presence. One of Biolchim’s distinctive traits has always Downstream, consumers and retailers pay greater attention to food production practices
been the openness to collaboration with all stakeholders and food safety. This leads growers to look for effective, safe and more natural solutions
aimed at bringing new, effective solutions to farmers to enhance productivity and quality. Biostimulants represent exactly the technology that
worldwide. Collaboration is the key to foster innovation in responds to this demand. Therefore, Biolchim is close to customers, growers as well as
product development and linked processes such as manu- producers’ cooperatives and associations to support the integration of the biostimulant
facturing, logistics, communication, that benefit all part- technology in fertilization strategies.
ners. That is why our innovation network, WIN, has grown
so much during the last few years. In 2020, which markets, globally, witnessed the fastest increase in
the sales margin?
Could you please talk a bit about Futureco Futureco Bioscience specializes in products for biocontrol and
How can we understand the WIN Plat-
Bioscience? biostimulation of agricultural crops. We provide the most demanding
form of Biolchim (is this a digital agriculture In 2020, we had significant growth of both, some new markets and some already
agriculture with the tools to enable production of the highest quality,
platform or an assistance tool of your product established markets, where we are present with subsidiaries. Europe, Asia and South
Futureco Bioscience is an agro-biotechnology company which always with respect for the environment.
development)? By standing with the view of the America were the areas with the greater increase. The demand for plant biostimulants
focuses on the research and innovation of products for crop protection
distributors and growers, how do those who and organic fertilisers is growing fast – and we are ready to respond, deliver our products
cooperate with Biolchim benefit from the WIN and support growers integrate them into their practice.
and nutrition. The company was founded in 1993 in Olèrdola (Barcelona). Earlier this year, Futureco Bioscience launched
platform?
Our mission at Futureco Bioscience is to lead the change towards Genomaat, an innovative custom-optimize service, to
With the rapid changes occurring in the world concerning envi- regenerative agriculture, creating value through scientific knowledge empower growers through soil microbiome data and
WIN is an international network of Research and De- ronmental challenges and sustainability, what are Biolchim's plans? and technological innovation. Characterized since its creation by an personalized analysis. What are the unique features and
velopment structured according to the principles of collab- ecological and sustainable approach, the company is distinguished by its advantages of this service?
oration, which involves leading universities and research Biolchim has implemented an environmental policy to minimize the impact of its in house organization, developing and manufacturing its products from
centers as well as commercial partners. Biolchim works activities and spread greater awareness and commitment to preserving the environment its own headquarters and marketing them globally. Futureco Bioscience Genomaat is different from other services, because it does not only
with its network in all phases of product development, in the medium and long term. All Italy-based companies in the Group have a certified en- is present in 40 countries and has partners, collaborators and associates analyze metagenomic data, but it also translates those into agronomical
from ideation to marketing, with two objectives: facilitate vironmental management system that guarantees correct management of all environmen- all over the world. recommendations and microbial solutions.
knowledge transfer from academic research to industry and tal aspects related to production processes. As part of this system, companies monitor The corporate values that single us out are several; our commitment Genomaat uses the biofunctional parameters provided by DNA
reduce the ‘time to market’ of the products. WIN partners specific indicators. Greenhouse gas emissions and energy consumption was reduced by to innovation, to quality and to the environment. Half of our staff is sequencing technology and big data integration to study and evaluate
test our products worldwide with local agronomic practices about 3% and waste to about 14% in 2019 compared to the previous year. Of the total made up of researchers who work in cutting-edge laboratories; only the status of each soil-crop ecosystem. We use a holistic approach.
and environmental conditions. This benefits farmers who waste tonnage, more than 60% is sent for physical-chemical treatment and about 12% is this year ENAC has accredited four projects and the Chemical Analysis Data from metagenomic analysis are integrated with knowledge and
can find new solutions sooner on the market, and it guar- recycled. Laboratory. Our commitment to the environment has been built into the experience, which go from microbial ecology to agronomy, plant
antees that our products perform in very different growing These are only some of the outcomes of the policy, that very concretely responds to DNA of the company since it was founded in the 90s. physiology and biocontrol or soil science. Once the diagnosis is
contexts. the environmental challenges we are facing.

complete, Genomaat offers tailor-made What are your plans for R+D+I or
microbial solutions and personalized product launches in the next five years?
treatment programs based on the company's
unique collection of microorganisms or on Futureco Bioscience has always been a
the native microflora of the analyzed plot, company which focuses on soil health and soil
coupled with "Bioenhancers", when needed. microorganisms developed in order to boost
These are a special line of products that will crop production. It suffices to say that one of
ensure that these micro-organisms adapt to our best selling products is Bioradicante. We
the environment quickly and effectively. are constantly improving this product using
new formulations. Added metabolites boost
Futureco Bioscience critical functionalities in our products’ portfolio
owns patented Lysobacter (as is already the case of Radisan and the line
enzymogenes strain B25 which of DEFENDERs), and with Genomaat our
provides nematicide activity and is metagenomic platform for microbial communities
able to promote plant growth. What engineering is applied to crop production. You
makes the B25-derived product B25 secreted molecules and compounds have a broad range of enzymatic activities, including can visit genomaat.com to know more. I am
RADISAN different from the similar acid and alkaline phosphatases, that dephosphorylate compounds and increase the availability of confident that this is the beginning of what bio-
products in the market? phosphorus in the soil at different pH values. B25 metabolites also have different peptidase activities precision agriculture will be in the near future.
that turn proteins into small peptides (producing signaling effect on crops) or free amino acids (source On the other hand, after the big success
What supports you for these achievements? Would you like to tell us
Undoubtedly, the added metabolic activity of N for crops). Moreover, B25 provides 42, 29 and 74 enzymes involved in nitrogen, potassium of NoFly, we are expanding our portfolio
about your great R&D capacity?
of our strain of Lysobacter enzymogenes and iron metabolism respectively. It also provides over 300 components working on the vitamins of biocontrol products. We are in the
strain B25 into each one of the microganules production and enzymatic cofactors, and 198 compounds involved in response and resistance to For more than 27 years, Futureco Bioscience has been strongly committed to R&D and registration process of two powerful broad-
of Radisan makes it stand out. biotic and abiotic stress. investing in highly qualified people. Today I can proudly say that this represents 45% of the spectrum biopesticides, which are very
We are very excited by the potential of With additional metabolites of Corynebacterium flavescens strain B2575, RADISAN WG company's staff. This definitely contributes greatly to the value of the company and the quality of effective against targets such as powdery
this strain as last year the European Patent considerably increases the rate of survival transplants and stimulates the vegetative growth. our products. mildew (Oidium neolycopersici , Glovomyces
Office (EPO) granted the patent for its All these synergisms with amino acids and microelements present in the formulation, constitute Our R+D Department is composed of an expert multidisciplinary team of researchers in chicharacearum , Leveillula taurica , Erisiphe
nematicide activity and ability to promote the added value of the product and are the basis of its proven root enhancing premium activity in the fields of Microbiology, Biochemistry, Molecular Biology, Plant Physiology, Biocontrol necator ), downy mildew (Bremia lactucae ,
plant growth (patent no. EP 3209132 B1). vegetable crops. At the moment, we are evaluating data from experimental trials about RADISAN (Phytopathology, Nematology, Entomology), Bioprocesses and Formulation. In terms of Phytophthora infestans , Plasmopara viticola ),
The metabolites of B25 are very beneficial effects on soil micro and macro biota. I am happy to share that we are observing unexpected infrastructure, our headquarters are fully equipped with laboratories for scientific research, a rots (Fusarium oxysporium ), sclerotinia , pox
to crop physiologic and metabolic processes. improvements, especially with earthworms, and the results will be published soon. pilot plant for the scaling up of formulations and growth chambers and greenhouses in which we (Rhizoctonia solani ), and bacterial diseases
evaluate, in semi-field conditions, the performance of the formulated prototypes. such as Pseudomonas syringae , Pectobacterium
Most recently, within the GENOMAAT and Futuromic projects, we have incorporated and Xanthomonas. Moreover, we have one
bioinformatic specialists into our R&D team. This is with the ambition of exploiting next- already patented bionematicide and two other
generation sequencing technologies when performing metagenomic analysis in-house. bionematicides which are in the process of
registration. We hope that they will be available
Futureco Bioscience is now present on six continents. Regarding the in the next few years.
strategies to promote biological agri-inputs, what are the differences between Further to this, we are exploiting the
developed markets (such as the United States) and emerging markets (such as cumulative knowledge of our multidisciplinary
Latin America)? team to assess and fine-tune the timing of
application and the optimal dosage that
Independent of geographical location, any food producer today, is looking for sustainable and will maximize the efficacy of our products.
innovative solutions to improve soil health and fertility in order to boost plant nutrition and reduce Futuromics is a transcriptomic analysis platform
inputs to sustain plant growth. It is assumed, and indeed proven, that optimal soil conditions make which explores the mechanisms of the action of
the soil nutrients more available. This in turn reduces the need for inputs and improves plant biostimulants and biopesticides in the market.
development, while increasing the tolerance of the plants to stress and pests. The aim of this is to understand, at a molecular
Emerging markets, such as Latin America, have widely diverse agro-ecological situations, level, how their application influences plant
with varying availability and quality of arable land and varying climatic conditions. Prospects for metabolism and physiology. The data from
agricultural development necessarily hinge on these considerations. this work will help us to show the efficacy of
Today, sustainable and eco-friendly food production is an unwritten rule, especially following our products and their impact on ecosystems.
the pandemic. Globalization supports the advancement of a shared knowledge and to expand the Through this research we will uphold the
reach of research, strategies and innovation, whereby the gap between developed and emerging values of quality and innovation that have made
markets is reduced. I would say that the striking exceptions of this time are the countries, which Futureco Bioscience a leading force in R+D+I
have no active plans for environmental preservation, neither in agriculture nor in any other sector. within agriculture.

What advantages are offered by microbiological Sulphur over other

Sulphur products? What makes Sultech® Sulphur different from its
AFEPASA: Serving Sustainable Agriculture with competitors?
128 Years of Experience in Sulphur Products Sultech® Sulphur is the fruit of many years of research, great effort for an SME like
AFEPASA, with the support of the Center for Industrial Technological Development
(CDTI). Its origin comes from the circular economy, through the microbial fermentation
of wastewaters. There are special bacteria that can transform hydrogen sulphide (H2S) into
elemental sulphur. In our company we transform this microbiological Sulphur into Sultech®
Sulphur, and with its exclusive formulation, we can greatly improve the quality and yield
of crops at a very competitive price.
In our R&D laboratory, we have developed a range of products with this type of special
sulphur that offers different modes of action, always oriented towards their uses.
AFEPASA specializes in Sulphur and is the oldest Sulphur manufacturer in the This Sultech has two different modes of action depending on the application, either soil
world. Their products are now present in over 80 countries, with 80% being utilized or foliar application.
as fungicides, fertilizers and biostimulants. AFEPASA is now the largest agricultural When we talk about soil application products, such as Microsul 40S, the mode of
Sulphur producer in Europe, and is constant growing, under the motto: “achieving action that we have demonstrated in laboratory tests and trials in real field conditions Where do you sell your products?
customer satisfaction”. is the action of a biostimulant of beneficial soil microorganisms, leading to improved Do you plan to sell them in new markets?
AgroPages interviewed Manel Montaño (CEO of AFEPASA), who talked about pH, electrical conductivity and nutrient availability, while enhancing the health of crops If yes, why are you interested in these
the key roles that Sulphur plays in the sustainable agriculture, as well as the company’s through the health of the soil. On the other hand, we have foliar application products, markets?
development, its unique technologies and business expanding plan. He also shared his such as Triumphalis, whose mode of action is as a direct biostimulant to plants. We are
expectations on potential distributing partners. different from our competitors, not only because our range of products are unique, but also Nowadays we are selling our products in 80
because we offer farmers organic and sustainable solutions for different field issues at very countries worldwide, especially in Europe, Africa
affordable prices. and the Middle East, and we are expanding our
Manel Montaño, CEO of AFEPASA markets to countries such as China, India and some
Apart from Sulphur, are there other products from AFEPASA that countries in Central and South America. We are
you would like to highlight? very interested in these markets because there is
increasing interest in new, high technological and
We have a unique and broad catalogue to help farmers overcome different problems sustainable agricultural solutions, for which we are
and increase crop quality and yield. One of the most serious problems affecting agriculture highly recognized.
Established in 1893, AFEPASA has now become a In your view, what key roles does AFEPASA’s Sulphur
worldwide, which will struggle over the next years, is global warming. One of the products
European leader in agricultural Sulphur products. How play in sustainable agriculture?
in our brochure that I would like to highlight is Soldefend. Soldefend will protect fruits What do you expect from
did AFEPASA achieve this?
Elemental Sulphur is a key player in the sustainable and organic
from the sun and reduces yield losses due to sunburn, as global warming is becoming a distributors if they are interested in
Becoming a European leader was not a short journey. AFEPASA agriculture. Firstly, as a pesticide, it is the only fungicide in the world that
major abiotic stress for the crops. selling your products?
was founded 128 years ago as a family company. Nevertheless, over does not generate any resistance in powdery mildew. In addition, it can also
AFEPASA’s technical support department is
the last 10 years AFEPASA was transformed and modernized through be used as an organic pesticide. Its application is well known by all farmers,
working constantly with our distributors. That’s
a strategic plan based on the Research and Development of new especially in vineyards, where 80% of Spanish farmers use AFEPASA’s
why we are always searching for distributors with
agricultural solutions, as well as a global expansion plan for exporting Sulphur, as well as in around 50% of Mediterranean vineyards, as the
good communication skills who can maintain the
our products to more than 80 countries in Europe, Africa and Asia. most cost-effective solution against powdery mildew. It is also used as an
ongoing communication between farmers and
Another key factor in our growth was the fact that over the last 10 acaricide. Another key point is that Elemental Sulphur is the first pesticide
AFEPASA. We need this because we want to help
years, the company doubled the number of talented employees and that 100% of the active substance comes from the circular economy.
farmers use our products in the most effective ways,
multiplied the investments in the factory, which has a state-of-the- On the other hand, as a fertilizer, after nitrogen, phosphorus and
and in the case our products do not fit their needs,
art infrastructure. I would like potassium (the “primary macronutrients”), Sulphur is the most important
we have an R&D department that can develop new
to highlight that we achieved “secondary macronutrient”, as recognized by the European Normative
products to help them.
steady growth, and, thanks Regulation (EU) 2019/1009 in 2019. The benefit of using Elemental
We know that each country is different, the
to our investment in quality Sulphur with other forms of Sulphur, as sulphates, is that Elemental Sulphur
needs of farmers are different, and there are local
processes and workflows, we are acts in a slow release process to increase the soil Sulphur content without
customs and laws that force us to adapt our products
certificated under ISO 14001, losing any product via lixiviation, improving the net profit of farmers and
to each country.
90001, 45001 and EMAS. This avoiding any environmental contamination. Elemental Sulphur also offers
This is why we need to maintain the constant
year we were awarded with the secondary benefits for the soil that are more important in certain conditions,
dialogue between our distributors and farmers.
Golden Medal of Sustainability as it reduces the pH of basic soils, equilibrate conductivity, and improves
by ECOVADIS. structure and fertility.

Why did you choose red seaweed as the raw material? Finally, our product is the only patented
seaweed biostimulant in the market. The
Sea6 Energy: Creating Innovative Products in a Red seaweeds are the only source of sulphated galactans, which are chemically distinct from
any other polysaccharides. They have unique bioactive properties. The extraction processes
nature of the patent makes it unique. We
have a granted product patent for our
Sustainable Way, by Combining the Strengths deployed can convert the sulphated galactans into versatile applications, ranging from renewable
bioplastics and agricultural biostimulants to immune enhancers and human food ingredients.
Biostimulant product in the major agricultural
markets globally. Unlike a process patent,
of Patented Ocean Farming System, Cutting Edge Sea6’s product patent protects other players
from entering the market with the similar
Research and Superior Agronomy Expertise

formulation. The patent covers the specific
signature of the derived molecules from the
juice and pulp of any red seaweed in the end
product. This makes the patent strong and
enforceable, adding a competitive edge to the
product.
Sea6 Energy has created a sustainable ecosystem by integrating the upstream and downstream activities
involved in cultivation of seaweed and converting the raw material into innovative products that have use across
industries. They have developed the world’s first system for large-scale mechanized ocean farming and along
with cutting edge technology and expertise, they are able to increase labour productivity, cultivate seaweeds in a
sustainable way, create novel products and guarantee the quality of the whole value chain from raw materials to
end products.
AgroPages recently interviewed Sri Sailaja Nori and Sowmya Balendiran from Sea6 Energy. They talked
about the advantages of their ocean farming system, red seaweeds and their patented biostimulant, as well as
strategies for taking their biostimulant products across the globe and their expectations from the potential partners.
Sea6 Energy has the world's ever sea tractor to grow sea plants throughout the year, even in deep-sea conditions. Seacombine®
The Photo of the batch tagged freshly harvested Red Sea Plant which we use in producing our
unique ocean farming system is a patented structure, and it has allowed us to integrate the backward supply chain right from
Sri Sailaja Nori
products
(Seacombine®) for seaweed cultivation to final packaging process. This harvesting technology has multiple benefits, including
Co-Founder and Director - R&D at
production. Could you please tell stringent control over the raw-material quality, complete traceability, and rapid scalability in a
Sea6 Energy
us the advantages (or advanced sustainable manner. Red seaweeds, in particular Kappaphycus and Eucheuma species, have a high yield potential
technologies) of this system and (> 100 dry tonnes/hectare/annum) and are rich in potassium. They also have a history of proven
how it benefits your seaweed-based large-scale cultivation (2 million metric tonnes per annum). In addition, they are also safe and
biostimulants? have been used as food and in the manufacture of food ingredients over the last five decades. The
vegetative nature of the seaweed makes it amenable to mechanical cultivation. Thus, there is no
Most of the seaweed-based biostimulants limitation on the raw material availability or scalability for novel applications. The growth-harvest
are based on temperate brown seaweeds. cycle of the red seaweeds is 45 days and multiple harvests are possible in a given year. This,
They are harvested from the ocean and then coupled with our SeaCombine® cultivation platforms, ensures a steady supply of sustainable and
sun-dried to increase their usability. There is traceable raw material
very little control over the age and quality of
these seaweeds as they are wild harvested. In
AgroGain® is a patented biostimulant developed by Sea6 Energy. What
addition, there are always vagaries about the
makes the product unique?
availability of the brown seaweed due to the
seasonality and government restrictions to Firstly, the active ingredient in the product is novel and different from the other seaweed-
harvest the seaweed. All these factors always based products in the market. The AI (Sulphated galactooligosaccharides and potassium) present
lead to inconsistency in the quality of the end in the product works by stimulating upregulation of various genes responsible for vital plant Sowmya Balendiran
product. functions such as cell division, photosynthesis and metabolism. Co-Founder and Director - Business
Our in-house engineering team The Photo of the SeaCombine®, in the process of farming red seaplants in deep sea conditions, off Our product stands out as it is entirely natural and highly potent, offering high performance at Development at Sea6 Energy
developed, Seacombine®, the world’s first- the coast of Bali, Indonesia very low dosages than the other seaweed-based products in the market.

Interviews
How do you guarantee product quality? R&D team can analyse the uniqueness and
benefits of the product.
Leading the
Sea6 Energy has identified and characterised the active ingredients responsible for the 2. Nationwide presence –This allows us
biostimulant activity. In addition, we have complete control over the raw material age and quality to work with a single partner in the entire
with our SeaCombine® powered cultivation technology. country
We have incorporated the “Quality by Design” approach in our manufacturing processes to 3. Distribution strength – We look at the
produce the products of highest quality and consistency. Every batch of the product manufactured
is subjected to analytical assays and plant bioassays. We use High-Performance Liquid
Chromatography (HPLC) and biochemical techniques to ensure all the batches adhere to specific
distribution strength regarding Plant Health
products, Crop focus, and others as this would
ensure the product reaches large audience.
field in
Biorationals
molecular signatures. 4. Global presence – We believe in
working closely and deeply with few partners.
Thus, we prefer partners with a global
presence so as to launch our products in other
countries.
5. Product Portfolio –This helps assess
the proper fitment and harness synergies for
both Sea6 and the partner.
6. Strategic crop presence – We look for
the presence of our partner’s existing business Certis Europe offers crop protection products and expertise to
in crop markets, that aligns with our product the horticultural, speciality and arable crop sectors across Europe.
strengths.
What are the things that Sea6

is currently working on? www.certiseurope.com
Our vision is to harness the potential
of red seaweeds (seaplants) to create a
sustainable bio-economy. While we have
The Photo of our facility in Indonesia. Sea6 has two production facilities currently – In India and in
commercialised the applications from
Indonesia
sea plants (biostimulant and plant health
products) with raw material available from
traditional cultivation methods, we have also
Sea6 Energy collaborates with large companies with a global footprint to demonstrated processes that can convert sea
distribute the biostimulant in the international markets. What is their strategy plants to food, feed, plastics, and fuels.
to promote the biostimulant in these markets? Biodegradable plastics and biofuels have
large volume applications and manufacturing
Our global partners are large companies with expertise in their niche industry. They have them require millions of tonnes of raw
experience in the local geographies. These large companies augment their strengths with Sea6 material and our proprietary SeaCombine®
Energy’s strengths. Like us, most of these companies have a strong R&D and product focus. Hence, technology would enable this.
they understand the strength of our product and can communicate the value proposition of the Over the next three to five years, Sea6
product to various stakeholders in the value chain. Energy will expand its ocean farming
Another strength these companies bring to the table is understanding the local markets in terms operations and demonstrate biodegradable
of the crops to be focused upon, end-user buying behaviour, channel strategy, and more. This helps plastics production at a pre-commercial
in proper product positioning. Finally, these companies have robust brand equity, and end-users trust scale. We will also launch products focused
these brands, which adds credibility to the product. on sustainable human food ingredients and
The partners we work with, have a strong focus on the Plant Health portfolio, and our product animal health.
fits their requirements, and hence, we can work synergistically with their existing portfolio.
Sea6 Energy plans to expand its presence in LATAM and Chinese markets.
What are your expectations while choosing a partner to collaborate with?
Here is our expectation checklist -

1. R&D Expertise – We believe this is a crucial aspect of choosing a partner because a good
2021.5.14 Agropage 半版广告 - bio 第二版 - 英文版[转曲].indd 1 2021/6/4 10:09:04

Can you please tell about your by the demand of consumers and planting alkali. A key factor is the fact that it reduces
understanding of the 3B new era efficiency. The aim is to continuously explore the use of pesticides, resists diseases and
and Leili's role and position in the the effects of 3B solutions to solve the improves quality if used in the pre-harvest
Working Together to Create a 3B joint creation of this new era?
Since its establishment, Leili has focused

imbalanced problems affecting crop farming.
The combined application of biotechnology
has great potential, which is not an isolated
period when pesticide applications are
forbidden. Leili’s test results in a tomato
field in Shouguang, Shandong, revealed that
New Era, Establish a Balanced

on the R&D and field application of algae- sector. Meanwhile, Leili will offer its partners tomatoes treated with conventional fertilizers
derived biostimulants. From our first product, relevant services to support the high value were infected by severe viral diseases at
Leili2000, to our current 3B-based product fruit industry. an incidence rate of 56.67%, while the
system, we have combined innovation application of Leili FucoVita at a 1,000-fold
Agricultural Value Community and application. The term, 3B, refers to

biostimulants, biofertilizers and biopesticides.
The 3B new era has already begun, with
Please give a brief introduction
of the technical principles of the 3B
upgrading. Under the framework
dilution + 30% conventional fertilizer showed
a disease incidence rate of 3.33%, controlling
96.67% of disease.
consumer’s increasing demanding safe and of reducing the use of chemical Moreover, Leili offers a 5 billion
delicious agricultural products, as well as pesticides and fertilizers and Trichoderma viride spore powder, Leili
with an increased social awareness of extreme improving agricultural quality, BioGuard TD. In 2018, Leili was the only
weather, high levels of food quantity and how promising are Leili’s 3B soil seaweed fertilizer R&D company that
quality, a simplified planting system and improvement complex technology participated in the “Chemical Fertilizer and
growing perception among growers, and and application prospects? Pesticide Use Reduction Research Program”
the series of measures taken by countries and the “Potato-targeted Fertilization and
Leili, a high-tech marine enterprise, was the first
to develop sustainable agriculture. The 3B In 2020, we released our alginate Pesticide Use Reduction Research Program”
to become involved in algal biostimulant development concept is now guiding the upgrading of saccharide, Leili FucoVita, targeting the under China’s 13th Five-Year Plan.
in China, as well as the first company in the world to agricultural production, with the aim of high content alginic acid and fucoidan With eight years of potato planting
develop an algae biostimulant-based functional fertilizer. dealing with the issues of stress, salinity and with special structures in algae. We have service experience and research and practical
Over more than 28 years of growth, Leili has developed alkalinity, as well as disease and the ban on used biotechnology and new biochemical achievements, Leili can help realise the
reputable products, such as Alga600, Leili2000, Algreen, the use of pesticides before harvesting. The technology to create an alginate saccharide optimized reduction and replacement of
3B new era will be a “blue ocean” in the agri- immunomodulator, which has a molecular fertilizers with natural active seaweed
AlgaSoil, DoubleWin, FucoVita, and BioGuardTD, which
inputs market. polymerization of 2-20 and is capable of organics, having screened out the high-spore-
have been successfully sold to over 80 countries and In this new era, Leili has positioned stimulating the potential of crops against number and disease-resistant biocontrol
regions around the world. itself as a 3B solutions provider, being diseases without creating substances that are bacteria, Bacillus subtilis and Trichoderma
In 2014, Leili put forward the theory of balanced committed to the continuous development harmful to the environment. In addition, it viride , which have a potato bacterial wilt
farming for the first time. Based on the theory of and upgrading of 3B solutions and driven also helps crops resist drought, saline and prevention rate of 20% to 25%, respectively,
biology and ecology while using alga, soil, crops and being also effective in controlling potato
black nevus and scab. Considerable success
human beings as study samples, Leili utilized modern
was also achieved in its application on
biotechnology to counter the ecological imbalance of soil
strawberry. At the Huairou organic planting
and crop nutritional disorders to achieve the balanced base in Beijing, the product was applied on
growth of crops, therefore, ensuring the quality and new strawberry varieties, such as Baili and
nutrition of agricultural products that maintain human Hongjuxing, preventing bacterial diseases and
health. reducing dead seedlings and rotten fruits. The
In an interview with AgroPages, Tang Jie (General plant survival rate was also up to over 95%.
The two products will enter the European
Manager of Leili Group) introduced Leili’s customized
market in 2022.
solutions for each local market, according to different In fact, we have seen a broader range of
crops, climate conditions and major plantations, to create application. Recently, good news came from
a balanced farming value community. Hebei Province, where a partner applied
Leili’s solutions throughout the process of
Tang Jie brown melon production without using any
chemical fertilizers and pesticides. Their
General Manager, Co-founder, Professor-level Senior
melons reached the purchase standard of
Engineer of Beijing Leili
the Shenzhen Pagoda Industrial (Group)
Corporation. The central part of the melons,
which had a Brix of 16 degrees while the

with the declining quality of arable land and The aim is to improve fruit quality, produce
improve soil and beneficial microorganisms. reputable fruits, support brand development
Such products include AlgaSoil, ChitinSoil on a sustainable basis, and enable growers,
and BacilluSoil. service providers and purchasers within the
industrial chain to enjoy the value offered by
Can you explain how Leili has the win-win cooperation in the fruit industrial
created a balanced farming value chain.
community through specific case For this reason, Leili established a
studies, such as potatoes, rice and laboratory and a soil crop testing center
bananas? to provide data support to the fruit
quality improvement program, under the
The balanced farming value community framework of balanced farming. At present,
was proposed by Leili in 2019 to offer its a standardized planting management
partners a standardized, multi-level and mechanism is being completed and perfected
diversified industrial chain service via to support high-quality fruit production. After
the integration of resources, to improve the application of Leili’s solutions, Musang
the quality and green and brand levels of King Durian was recently brought into the
agricultural services. Currently, Leili focuses “100 Superb Fruits” global plan. Furthermore, internationally advanced level.” has brought the technical achievement to
on providing services for high-value fruits, a cooperation agreement was reached between This achievement also offers a new commercialization, resulting in the release
such as melon, grape and strawberry. Miss Fresh and Mitong Watermelon and approach and a product for soil acidification of products such as Leili AlgaSoil BioGuard
side part is 11 degrees, tasted like rock candy. in 80 countries. The technological system In 2014, Leili put forward the theory of Yangfeng Crisp Persimmon. regulation, aggregate structure construction TD, BacilluSoil and Healthiper, which
The entire melon plants appear very healthy of balanced farming is originated for marine balanced farming for the first time. Based on and the prevention of soil borne diseases, are expected to effectively improve land
without powdery mildew or other diseases, biotechnology-based agricultural application, having established an application system production efficiency, land output rate and
the theory of biology and ecology while using Can you talk about Leili’s
and none were showed premature growth. which is defined according to their functions and solved the problem of the growth resource utilization ratio, to restore the
alga, soil, crops and human beings as study product deployment in other types of
This is a successful case of an application as follows: of high-value crops caused by soil soil and improve the quality of agricultural
samples, Leili utilized modern biotechnology applications, such as seed treatment
carefully handled by the farm via scientific - Crop regulator products: To regulate constraints. It is a breakthrough in the products, generating better economic benefits
to counter the ecological imbalance of soil and soil amendment?
planting management and the innovative the vegetative growth and reproductive and crop nutritional disorders to achieve the key technological development, such as for growers.
and high-frequency use of Leili’s Alga600, growth of crops through functions such as balanced growth of crops, therefore, ensuring In terms of soil amendment, last year, the soil aggregate structure construction
Soft Guard (applying at 10-fold) and the promoting flowering, protecting fruiting, the quality and nutrition of agricultural Leili released a technological achievement and heavy metal passivation through Any further thoughts
novel product, FucoVita, meaning that there controlling flourishing, increasing saccharide products that maintain human health. after 11 years of research and development, a algal polysaccharide, chitosan and the and suggestions on the healthy
are many new opportunities for Leili’s 3B and extending shelf life, as well as to improve To fully promote the balanced farming marine polysaccharide-microbe complex for antagonism on harmful microbes in the soil development of global agriculture?
solutions, which will help growers reduce nutrients accumulation, ensure the original theory, in 2018, the Leili Group launched soil amendment targeting soil constraints. The via Trichoderma viride , Bacillus subtilis
costs and labor and achieve higher quality taste of fruits and vegetables, and improve a “100 Superb Fruits” global plan, which results were appraised and evaluated by an and Bacillus amyloliquefaciens . As a result, Reducing the use of chemical fertilizers
and yield. After more applications, there will commodity value. Such products include is a bilateral or multilateral fruit industry expert group, which regarded it as a “scientific a marine polysaccharide-microbe complex and pesticides is a general trend. The
be greater benefits to the upgrading of local Alga600 and Leili2000. chain program initiated at Fruit Logistica and technological achievement,” concluding, improvement system was developed. COVID-19 pandemic will also change the
industry. - Crop care products: Used for crop in Berlin, Germany, in February 2019, and “The achievement has, in general, reached an Currently, the upgrading of soil amendment patterns of the agricultural industry and
issues related to immunity declination, supported by the China Quality Agricultural people’s consumption consciousness to a
Please explain the core plague prevention, stress resistance and crop Product Development Service Association. great extent, meaning that the development
advantages of the raw materials, protection for healthy growth, to prevent A subsequent strategic partnership was and application of products must be more
core supply chain and product line bacterial, fungal, viral and physiological established with the Shenzhen Pagoda efficient. Today’s agricultural development
of Leili. diseases, which will contribute to the Industrial (Group) Corporation and the is also the integrated development of the
recovered growth of crops after floods, iFresh Asia Fruit and Vegetable Industry industrial chain, as well as a chain-to-chain
Sargassum is the main raw material in droughts, cold weather and pesticide damage. Expo, which has received positive feedback development and an upgrading of the whole
Leili’s algae biostimulants. In line with our Such products include SoftGuard, FucoVita from more than 100 fruit industry players chain, requiring joint efforts and contributions
R&D, we extracted chitosan oligosaccharides and BioGuard TD. both at home and abroad. The global from everyone involved to help achieve the
from shrimp and crab shells and cultivated - Crop nutrition balancing products: plan assumes responsibility for quality sustainable development of global agriculture.
probiotics and marine minerals with marine To solve crop problems related to yield improvement, increasing farmers’ income and
nutrients. Leili’s core advantage lies in its and quality decline, as well as low nutrient ensuring consumer health while operating
technological system and channel advantages use efficiency caused by the unbalanced in cooperation with local and international
based on balanced farming. We have more application of chemical fertilizers. Such high-quality fruit bases, enterprises, service
than 30 core technologies in biostimulants products include Leili DoubleWin. providers, purchasers, industry media and
and we have established marketing networks - Soil amendment products: To deal associations to create standardized orchards.

Registration Policies Registration Policies
in case a product has dual action against abiotic and biotic stress it is only, the implementation of most of the actions and initiatives of the F2F
absolutely eligible for registration under the plant protection framework and Biodiversity strategies will take some time. However, the Directive
The Core and Changes in Registration as respective substance/product categories such as ‘elicitor’ or ‘plant
activator’ are already included and covered by Regulation 1107/2009.
128/2009 on the sustainable use of pesticides as underlying legal basis
for many of the Green Deal targets – often neglected for many years –
Regulation for Biopesticides and Biostimulants Other practical examples highlight that changes in the legal and
regulatory procedures for plant protection products are ongoing on
is already available and allows for direct action. Based on these already
available prerequisites, in March 2021 a six month foresight study was
in Key Markets: EU, US, India and Japan

many levels and that efforts to implement EU’s Green Deal, Farm to launched to assure that by 2030 the pesticide use and risk reduction
Fork, Biodiversity and Sustainability goals as well as the General Food targets announced in the Farm to Fork and Biodiversity Strategies can
Law are rapidly increasing. This is not only due on EU, but also on be fulfilled. Also in regard to other Green Deal targets several tangible
national levels in the individual Member State as foreseen by several actions are already taken. The European Commission published the basics
legislative acts, e.g. the SUD (Sustainable Use Directive 128/2009) and for an action plan for the development of future organic production in
the respective National Action Plans. According to the Sustainable Use March 2021. The action plan builds up on the upcoming new legislation
Trends and developments for biopesticides and biostimulants in EU Directive, for example ‘Member States shall take all necessary measures on organic farming (Regulation 2020/1693) of November 2020 amending
to promote low pesticide-input pest management, giving wherever Regulation 2018/848 on organic production and labelling of organic
In the EU, the last months have seen especially in case of closely related substances possible priority to non-chemical methods, so that professional users of products, which enters into force on 1 January 2022. Already designed to
significant changes in regard to the current as well (e.g. certain botanicals). The sole claim of pesticides switch to practices and products with the lowest risk to human boost the organic farming sector, the new regulation in any case includes
as the future regulations for biopesticides and abiotic functions for a product in order to fall health and the environment among those available for the same pest several respective measures such as rules for a more uniform approach
biostimulants. One of the key issues of course is under the fertiliser/biostimulant framework may problem’. Based on this argumentation, the Swedish authority rejected an to reduce the risk of accidental contamination from pesticides, steps
the step from national biostimulant regulations to not be sufficient, considering the vast amount application for re-authorisation of a chemical insecticidal plant protection to simplify organic farming certification for small farmers via a new
EU harmonised rules under a fertiliser framework. of scientific literature and public information product used in silviculture against beetles, arguing that widely-used non- system of group certification, or a strict control system and precautionary
Entry into force of the new EU fertiliser Regulation on functions of many substances available, the chemical methods are available and non-authorisation of the chemical measures along the entire supply chain to safeguard organic products.
Dr Lars Huber 2019/1009 has brought on several changes. competitive position between biostimulant and product therefore does not cause any significant economic or practical The new regulation also requires producers in third countries to comply
Senior Manager Regulatory For one, the new regulation will significantly plant protection product manufacturers and disadvantages for the forest owners. The decision for non-authorisation with the same requirements as farmers producing in the EU. Further
Affairs, Head of Biorationals, simplify market entry for biostimulant products distributors, etc. This could lead, for example, was confirmed by law courts in the meantime. The Swedish decision is examples for actions already initiated are several public consultations
Fertiliser, IPM at Scientific from its applicability in 2022 onwards, provided to the requirement to register products under one of the first in the EU substituting chemical plant protection products of the EU Commission ongoing at the moment, e.g. on a new EU soil
Consulting Company (SCC), that they are compliant to the new regulation, as the plant protection product framework which based on the availability of more environmental friendly alternatives. In strategy or in regard to the revision of the SUD and stricter rules for the
Germany there will be harmonised rules and procedures previously have been marketed under the addition, the Swedish government decided to completely ban the use of sustainable use of pesticides. Several ongoing or upcoming actions of the
applicable for all EU Member States. However, national fertiliser laws as ‘biostimulants’. One, plant protection products in certain areas, such as public areas, parks or Commission are in turn complemented by EU Parliament initiatives. The
by including biostimulant products and explicitly almost historical, example are Trichoderma gardens. Exemptions from the ban are only foreseen for plant protection Commissions’ public consultation on an EU soil protection strategy, for
excluding them from EU plant protection products species which, at least in many countries, where products that are deemed to pose a limited risk to human health and example, is mirrored by an EU Parliament draft motion for a resolution
Regulation 1107/2009, the new fertiliser regulation brought onto the market as biostimulant, plant the environment, that is mainly products containing active substances on Soil protection, published in February 2021. As with many topics
not only closes a regulatory gap through bringing or soil aid products for decades, but which more classified as low risk according to Regulation 1107/2009 and thus, referred to in the Green Deal, the EU Parliament not only highlights the
biostimulants under harmonised rules from June and more have to be approved/authorised as biorational products. importance of certain actions (in this case soil protection) in regard to
2022 onwards, but opens up another one. This is plant protection products due to their fungicidal The examples of the recent Swedish decisions are a good indication environmental or human and animal health problems and needs which
mainly due to the fact that the official definition potential. As the last months indicate, the ‘dual for possible upcoming changes triggered by the new EU’s Green Deal, a are no longer disputed by the majority of stakeholders, but rather stresses
of biostimulants, eligible for registration under use’ potential of a substance or product harbours “roadmap for making the EU's economy sustainable by turning climate the economic relevance of such measures, emphasising costs caused by
the EU framework in future, is mainly a legal many possibilities for interpretations and and environmental challenges into opportunities across all policy areas” ‘inaction on soil degradation, with estimates in the Union exceeding €50
and regulatory, not a scientific one. According to possible problems. According to current ongoing (EU COM 11 December 2019). In regard to agriculture in general and billion per year’.
Regulation 2019/1009 biostimulants are defined discussions in the Standing Committee on the use of plant protection products in particular, the most important The European Green Deal also underlines the need to raise public
as products ‘stimulating plant nutrition processes Plants, Animals, Food and Feed, the regulatory components of the Green Deal are the so-called Farm to Fork (F2F) awareness and include the general public in these reforms. A major aim
independently of the product’s nutrient content status of some active substances are already Strategy and the Biodiversity strategy. Key actions are for example: is to build up the trust of EU citizens in the agricultural sector, the food
with the sole aim of improving one or more of under discussion. In the specific case, the plant • Reduction of the use and risk of chemical pesticides by 50% by supply chain and in the availability of safe, residue-free food. Based
the following characteristics of the plant or the protection product framework for an existing and 2030 on the synergistic principle of EU legislation, part of the Green Deal
plant rhizosphere: (a) nutrient use efficiency, (b) approved chemical active substance is challenged • Reduction of the use of more hazardous pesticides by 50% by 2030 measures are already anchored and reflected in the new General food law
tolerance to abiotic stress, (c) quality traits, [or] by some Member States. The Member States • Revision of the Sustainable Use Directive (for pesticides; SUD) which entered into force in March 2021. General Food Law provisions
d) availability of confined nutrients in soil or consider the substance as plant biostimulant to significantly reduce use and risk and dependency on pesticides have a main focus on the transparency of the food chain and thus also
rhizosphere’. However, plants normally do not according to the new definition and thus falling and enhance Integrated Pest Management and to improve the link the registration procedures and use of plant protection products. With
adhere to regulatory definition and thus do not outside the scope of the plant protection products between the objectives of the SUD and other legislation linked to their Regulation 2019/1381 – on the transparency and sustainability of the EU
differentiate between abiotic and biotic stress. regulation. In this context it is important to implementation, such as the Common Agricultural Policy (CAP) and risk assessment in the food chain – various new regulatory procedures
Many of the plants’ stress defence systems note that the new fertiliser regulation does not Water Framework Directive were introduced. Some examples are the requirement for mandatory
are involved in both, abiotic and biotic stress allow for products to have biotic stress action. • Boost the development of EU organic farming area, with the aim to notification of all studies used for an active substance approval procedure
response. Thus, differentiation between the legal On the other hand, if a product is effective only achieve 25% of total farmland under organic farming by 2030 before the start of the studies, the so-called Pre-Submission and Renewal
frameworks in which a product is to be registered against abiotic stress it does not fulfil the criteria • Revision of the EU Thematic Strategy for Soil Protection by 2021 Pre-Submission Advise as well as the mandatory use of the electronic
may become difficult for many products, of the plant protection regulation. However, With the Green Deal being in place in the EU since December 2019 data submission platform IUCLID (International Uniform Chemical

Information Database) for evaluations carried out on EU level such as theory, could achieve the desired effect, namely to make biostimulants
Biopesticide registration process and trends in India
plant protection product active substances, MRL evaluations or basic more easily available on the market and thus complement farmers’
substance approvals. This shall also guarantee an early publication of toolbox to support sustainability and Green Deal goals. However, the new
submitted data and evaluation results and easy access on the results for fertiliser/biostimulant regulation explicitly allows for ongoing national
The registration of biopesticides in India is governed under the Insecticides Act 1968 and
all stakeholders as well as the public. Access is guaranteed by the EFSA registration/notification procedures, provided they do not infringe EU
handled by the Central Insecticides Board (CIB). Realising the importance of biopesticides in
webpage. As the first months under the new Regulation already have standards. And thus, the new fertiliser regulation is accompanied by
agriculture, CIB has approved several categories of products such as:
shown, the new requirements are changing the daily work in the plant another new regulation (Regulation 2019/515) simplifying the mutual
1. Entomotoxic bacteria (Bacillus thuringiensis , B. sphaericus , etc.)
protection product registration procedure significantly. recognition procedure for nationally registered products and the free
2. Antagonistic bacteria (Paenibacillus polymyxa , Pseudomonas sp.)
Besides plant protection, the Green Deal and the General Food law movement of fertiliser/biostimulant products in all EU Member States.
3. Entomopathogenic fungi (Beauveria bassiana , Metarrhizium anisopliae, Nomuraea rileyi ,
also influence the registration of biostimulants from a regulatory point In addition to the few examples described above, there are many
etc.)
of view. The importance of biostimulants to fight, for example, the more influencing plant protection product and fertiliser/biostimulant
P. Balakrishna Murthy, Ph.D. 4. Antagonistic fungi (Trichoderma sp., Verticillium sp., etc.)
consequences of climate change, i.e. heat, drought and salinity stress or registration, and there are more to come. Overall, it seems that the
D.Sc., Scientific Business 5. Baculoviruses (Nucleopolyhedroviruses (NPV) and Granuloviruses (GV))
the need to reduce mineral fertiliser inputs, was the basis for inclusion process of Greening and Sustainability, long neglected in the EU,
Advisor to SCC GmbH in India 6. Botanical pesticides (Pyrethrum, Karanjin, Neem, Cymbopogan , etc.).
of biostimulants in a harmonised EU-wide regulation. This, at least in significantly gains momentum.
CIB has developed guidelines and data requirements covering physical-chemical properties
including methods of analysis, toxicity (e.g. acute studies), ecotoxicity, packaging, and labelling
information. Biological characteristics include DNA fingerprints reported by the National Bureau
of Agriculturally Important Microorganisms (NBAIM), certifying the strains submitted by
applicants. Efficacy data need to be generated by controlled research centres according to the Indian
Council of Agriculture Research (ICAR/state agricultural universities (SAUs). In addition, CIB has
developed standards (minimal infrastructure facilities) to produce biopesticides in regard to general
requirements for production, mixing, formulation, laboratory equipment, etc.
In 2019, CIB reclassified the registration categories for biopesticides: Tier-I category
(Insecticides Act 9(3b)) with temporary registration based on limited data and Tier-II-category
(Insecticides Act 9(3)) with permanent registration based on a complete data package. The
committee also decided that handle registrations (me-too) for the same strain/compound of
Biopesticide registration process in US biopesticides (including also botanical products and pheromones) under the Tier-II category, because
these have already been introduced in the country according to the relevant provisions of the Law.
Beside the above mentioned regulations, the Indian government has introduced several other
The U.S. EPA defines biochemical pesticides as pesticidal substances that:
policy areas and regulations fostering the organic farming sector. This includes for example the
• are naturally occurring chemicals or are synthetically derived equivalents;
National Programme for Organic Production (NPOP) launched in the year 2001 by the Agricultural
• have a history of exposure to humans and the environment demonstrating minimal toxicity, or in the case
and Pro-cessed Food Products Export Development Authority (APEDA) under the Ministry of
of synthetically derived biochemical pesticides, are equivalent to a naturally occurring chemical that has such a
Commerce and Industry. The institutional framework for accreditation and certification of organic
history; and
agriculture was the major goal of NPOP, which gained recognition agreements with the European
• have a nontoxic mode of action to the target pest(s).
Union and United States Department of Agriculture (USDA).
Biochemical pesticide registrations are generally significantly less expensive and usually take less time to
Further, The National Mission for Sustainable Agriculture (NMSA) under the National Action
register than conventional or antimicrobial pesticide product registrations. There is a reduced data set for these
Plan on Climate Change (NAPCC), was launched in the year 2010, aiming at sustainable pest
naturally occurring chemicals compared to other registrations. Therefore, companies can have considerable cost
Cody Kendrick management and intensifying research, commercial production, and marketing of biopesticides. The
savings in studies. In addition, the fees to register a biochemical pesticide with the U.S. EPA in PRIA (Pesticide
Sr. Product Manager, major focus was to develop new biopesticides and technologies such as sterile insect techniques,
Registration Improvement Extension Act) are typically lower as compared to registration costs for conventional
Regulatory Affairs Landis transgenic insects, novel botanicals, semio-chemicals and microbial metabolites for pest control
pesticides. The review of a biochemical pesticide registration submission by the EPA also takes less time. Thus,
International, Inc., U.S. and the use of disease forecasting systems (NMSA 2010). Zero-Budget Farming, introduced by
a company can save a lot of money and time upon submission.
the government of India in 2015, was a huge success in southern states encouraging the use of
For example, to register a new active ingredient for food use a company may expect the following PRIA
biopesticides.
costs upon submission:
For the Indian biopesticides market a Compound Annual Growth Rate (CAGR) of 7.3% during
• Biochemical: $33,506 and 18 months for U.S. EPA to review
the forecast period (2020-2025) is assumed. The Indian biopesticides market was dominated by
• Conventional: $790,737 and 24 months for U.S. EPA to review (or $658,947 and 18 months if the active
bioinsecticides in 2019, assumed to stay stable during the forecast period. Wheat, cotton and rice are
ingredient is considered reduced risk). Costs may be lower depending upon the proposed use.
the major crops cultivated in the country. Bioinsecticides related to these crops are expected to have
Because less data is required to support biochemical pesticide products, generally those proposals can
a higher increase in sales as compared to products used in other crops.
be reviewed by U.S. EPA in less time and get to market faster than conventional chemical products. Due to
Increasing awareness regarding food safety, organic farming, government policies and subsidies
the U.S. public concern with conventional pesticides, the EPA is interested in registering more biochemicals.
are currently the major factors driving India’s biopesticides market. According to Fibl (Research
If companies are interested in marketing their products with organic labelling, most products for organic
Institute for Organic Agriculture) statistics, the area under organic cultivation in India increased
cultivation are biochemical products. However, there are conventional products that have organic labelling.
from 1.5 million hectares in 2016 to 1.9 million hectares in 2018.

Registration Policies
Biostimulant regulations and trends in India industry. The committee is to control the quality and specifications of The re-evaluation program will start in 2021 requiring a review
all biostimulants and ensure the use of safe substances and organic of all registered plant protection products every 15 years. Though
Recently, a regulatory body as well as compliance requirements compounds in manufacturing of products. The agrochemical landscape several biopesticides already have been registered as plant protection
for the biostimulant market in India have been established in line in India is dominated by farming-related services and specialty products, MAFF plans to establish a new guideline for biopesticides
with the Fertiliser Control Order (FCO), issued in 1985. The Indian products. The Federation of Indian Chambers of Commerce & Industry launching a re-evaluation process also for biopesticides.
biostimulant market is largely dominated by micro, small and medium (FICCI) categorises biostimulants under the latter category alongside Furthermore, on 12 May 2021, MAFF released the so-called
sized enterprises (MSME) and currently estimated to be worth about micronutrients, biopesticides, and biofertilisers that have recently begun "Green Food System Strategy – Achieving both productivity
US$ 201mn becoming one of the fastest-growing sub-sectors of the to permeate the markets. Guiding the policymaking process toward improvement and sustainability of food, agriculture, forestry and
economy. The new regulations require manufacturers to register products levelling the playing field for both small and large players will help the fisheries through innovation". Similar to the European Farm to Folk
at authority providing a set of information on chemistry (composition, sector contribute close to 20-25% of annual growth. strategy, the "Green Food System Strategy" aims to achieve several
analytical methods, shelf-life), bio-efficacy trials conducted by the Indian goals such as CO2 zero emission, 50% reduction of agrochemical
Council of Agricultural Research (ICAR), state agricultural universities risk or 30% reduction of chemical fertilizer use by 2050. To archive
(SAUs) preferably in agro-ecological zones, as well as toxicity data and References the strategic goals, MAFF is encouraging to develop and introduce
heavy metal analysis. The regulations also allow for the establishment http://ppqs.gov.in/divisions/central-insecticides-board-registration- biopesticides and related nature-based technologies. With the
of a regulatory body to monitor the end-to-end movements within the committee implementation of the “Green Food System Strategy”, the role of
biopesticides in Japan’s agricultural market is expected to gain in
importance.
Biostimulant registration and trends in Japan
Biostimulants are not legally defined in Japan. However,

several products considered as biostimulants are broadly used
Biopesticide registration process in Japan with registration under the Fertiliser Control Law or Soil Fertility
Enhancement Act. In response to the amendment of the Fertiliser
Regulation in the EU, an industry group in Japan has been established
Biopesticides are widely used in Japan since the 1950s, with insecticides based on Bacillus to actively promote the communication with the competent authorities
thuringiensis (Bt) being introduced in the 1980s. Biopesticides are basically regulated under the in order to facilitate the standardisation of biostimulants. With the
Agricultural Chemical Regulation Law. However, from 1990 onwards, discussions on safety assessment newly adopted "Green Food System Strategy", MAFF is targeting the
of biopesticides ensued as a result of the development of novel products such as microbial pesticides. In reduction of chemical fertilizer use, by recognizing biostimulants as
1997, the Ministry of Agriculture, Forestry and Fisheries (MAFF) established a guidance for biopesticide a valuable tool to lower fertiliser inputs and to reduce environmental
registration listing data requirements and numbers of studies. The guidance defines viruses, bacteria, impacts. The Japanese Crop Protection Association has announced
fungi, protista and nematodes (with symbiotic bacteria producing active ingredients) as biopesticides. that industry will proceed with developing biostimulants to support
Natural enemies such as parasitoid wasps and predaceous insects as well as active substances derived this strategic goal. This can accelerate standardisation of the
from microbes have been excluded from the scope of the guideline. biostimulant regulatory background in Japan.
Hidetoshi Goto, Ph.D.
Manager Regulatory Scientific While for the registration of chemical pesticides, a full data package as set out under the Agricultural
Department at SCC Scientific Chemical Regulation Law is required, for the safety assessment of biopesticides a tiered approach is
Consulting Company Japan accepted, since most biopesticides are widely occurring in the natural environment and considered not References
K.K. to be harmful to humans and animals. In particular, the tiered approach is applied for the toxicological http://jppa.or.jp/archive/pdf/52_01_10.pdf
safety assessment of biopesticides under the guidance, i.e. 1. single dose studies, 2. repeated dose studies https://www.env.go.jp/water/report/h14-04/hontai_all.pdf
and 3. reproductive studies. If evidence indicates potential hazards, higher tier studies are required. https://www.acis.famic.go.jp/shinsei/9-5090.pdf
In 2003, the Food Sanitation Law was amended to implement a positive list system setting maximum http://www.acis.famic.go.jp/shinsei/9-5090b.pdf
residue limits (MRLs) for all pesticides. Biopesticides are not subject to the positive list. This is an
important incentive for biopesticides which have gained attention as key technology to achieve lower
agrochemical inputs.
Trends and developments in the Japanese biopesticide market
MAFF amended the Agricultural Chemical Regulation Law in 2018 and introduced a re-evaluation
program for all plant protection products registered in Japan in line with the latest scientific information.

Biopesticide has not been clearly defined accounted for about 63%. registration of biopesticides. This will
in China. However, from a registration In recent years, new biopesticide varieties greatly promote the market entrance and
policy perspective, the “Data requirement have emerged on the market. From 2017 to application of such products, providing
on pesticide registration” makes a separate 2020, 72 new pesticide active ingredients more opportunities for the development of
Biopesticide Active Ingredients Get

provision on biopesticides including were being registered in China, of which 31 biopesticides.
microbial pesticides, biochemical pesticides were biopesticides, accounting for 43%. The The newly revised “Data Requirement
and botanical pesticides. Natural enemies proportion of biopesticide active ingredients on Pesticide Registration” implemented in
Policy Support for Entrance into

are not required to be registered anymore. has increased significantly in recent years. 2017 reduces the time consumption in a
While agricultural antibiotics and transgenic Although a large number of biopesticide biopesticide test and registration process. The
plants (including embedded plant protectants) active ingredients have been registered in residue test requirements have been reduced
are not identified by the national regulations China (table 1), the production is concentrated for microbial pesticides, botanical pesticides
Chinese Market as to their classification as biopesticides.

Agricultural antibiotics are often recognized
as biopesticides in the industry, while
in a few product varieties. The most
produced five microbial pesticide products
are Bacillus thuringiensis (top 1), Bacillus
and part of biochemical pesticides. Of these,
microbial pesticides are exempted from 19
environmental toxicological tests; botanical
such products are registered following subtilis , Helicoverpa armigera nuclear pesticides are exempted from 3 environmental
the requirement of chemical pesticides. polyhedrosis virus, Metarhizium anisopliae fate tests and 17 environmental toxicological
Genetically modified organisms are subject and Paenibacillus polymyxa , accounting for tests, and biochemical pesticides are exempted
to the evaluation by the National Agricultural over 75% of the total microbial products. from 21 environmental toxicological tests and
GMO Safety Management Committee The most produced five biochemical all environmental fate tests.
in accordance with the “Regulations on pesticide products are gibberellic acid, Moreover, since the implementation of
the safety control of genetically modified oligosaccharins, brassinolide, triacontanol and this 2017 policy, natural enemies have been
organisms in agriculture”. 14-hydroxylated brassinosteroid, accounting exempted from registration.
for about 70% of the total biochemical On September 30, 2020, the Pesticide
Number of biopesticide active pesticide products. The top five botanical Management Division of the MOA issued an
ingredients in China and changes in pesticides are matrine, camphor, rotenone, incentive that was called the “Implementation
recent years TDS and triptolide, which account for about of Green Channel Management Action
80% of total botanical pesticides. for Pesticide Registration Review”, which
Some 121 biopesticide active ingredients was in favor of microbial pesticides,
(agricultural antibiotics included in this
Policies facilitate registration of botanical pesticides, biochemical pesticides
China's green pest management area reached nearly 1 billion mu (1 mu = 0.067 hectare) in 2020, counting) are registered in China, accounting biopesticides and agricultural antibiotics produced via
with green pest management being applied on 41.5% of major crops to control insect pests and for 16.8% of the total pesticide active biological fermentation, where priority is
pathogens, which was 18.5% higher than 2015, according to the Ministry of Agriculture and Rural ingredients. A total of 3,969 biopesticide The sustainable development of given to these products that meet the green
Affairs of China (MOA). product registrations were granted (including agriculture needs policy support. The MoA channel requirements in respect of a technical
The promotion of biopesticides is imperative for the development of green agriculture. In China, agricultural antibiotics), accounting for 8% of proposed an initiative to reduce pesticide use review which should be processed speedily
the use of chemical pesticides had maintained a negative growth over the past five years, while the the total pesticides. Among the biopesticide and improve its efficiency, and introduced provided that quality and safety were not
use of biopesticides was on the rise. The promotion of such products is accelerating. product registrations, agricultural antibiotics a series of incentives to encourage the
By Joyce Wang compromised. This green channel process
Editor of AgroPages is constantly improving. As there is a large
[email protected] number of pesticide registration applications
in China each year, the waiting list is quite
Definition
long. The implementation of the green
• Microbial pesticide: pesticide using living organisms of bacteria, fungi, virus and protozoon or
channel process will help to cut down time
gene-modified microorganism as an active ingredient.
for biopesticide registrations.
• Botanical pesticide: active ingredients derived directly from plants.
The National Plan to Boost High-quality
• Biochemical pesticide: meeting both following two requirements: 1) there is no direct toxicity
Development of Agriculture (2018-2022)
to the target pests, but it regulates growth, disturbs mating or allures pests; 2) natural compound,
has called for accelerated development of
or the structure is identical to a natural compound in case of a synthesized compound (isomer ratio
green agriculture, which requires great effort
difference is allowed). It can be semiochemical, a natural plant growth regulator, natural insect
being made on promoting the application of
growth regulator, natural plant elicitor and other biochemical pesticides.
green pest management. The policies of the
• Natural enemy pesticide: live organisms (apart from a microbial pesticide) that control pests.
Chinese government are being put in place to
• Agricultural antibiotics: a secondary metabolite with pesticide functions created via a microbial
create opportunities to promote biopesticides.
fermentation.
It is foreseeable that the market entrance of
biopesticides will accelerate in the years to
come, which will hasten the development of
sustainable agriculture in China.

Table 1. Active ingredients of microbial pesticides, biochemical pesticides,

botanical pesticides and agricultural antibiotics registered in China
WHAT IF
CORN COULD FIX
Category Active ingredient
Bacillus thuringiensis , Bacillus thuringiensis israelensis , Bacillus methylotrophicus strain 9912, Bacillus
methylotrophicus strain LW-6, Bacillus marinus , Bacillus firmus , Bacillus sphaericus , Bacillus subtilis , Bacillus
NITROGEN?
cereus , Pseudomonas fluorescens , Paenibacillus polymyxa , Brevibacillus laterosporus strain A60, Empedobacter
Bacterium
brevis , Bacillus licheniformis , Bacillus amyloliquefaciens strain B7900, Bacillus amyloliquefaciens strain B1619,
Bacillus amyloliquefaciens strain PQ21, Bacillus amyloliquefaciens strain LX-11, Bacillus amyloliquefaciens strain
AT-332, Rhodopseudomonas palustris strain PSB-S, Rhodovulum sulfidophilus strain HNI-1
Metarhizium anisopliae , Beauveria bassiana , Trichoderma harzianum , Paecilomyces lilacinus , Verticillium

Fungus chlamydosporium , Conidioblous thromboides , Coniothyrium minitans strain ZS-1SB, Conithyrium minitans strain
CGMCC8325, Pythium oligadrum
Microbial
pesticide
With Envita™ and N-Fix®, Now it Can.
1) NPV: Helicoverpa armigera nuclear polyhedrosis virus, Ectropis oblique nuclear polyhedrosis virus, Spotoptera
exigua nuclear polyhedrosis virus, Autographa californica nuclear polyhedrosis virus, Spodoptera litura nuclear Envita and N-Fix contain nitrogen fixing bacteria that works throughout
Virus
polyhedrosis virus, Mamestra brassicae nuclear polyhedrosis virus the foliage and roots and provides a season long source of nitrogen exactly
2) CPV: Dendrolimus punctatus cytoplasmic polyhedrosis virus where and when it is needed to maximize yield. Applied in-furrow or as
3) GV: Pieris rapae granulosis virus, Plutella xylostella granulosis virus, Pseudaletia unipuncta granulosis virus,
a foliar spray, Envita and N-Fix work on a wide range of crops including
cockroach virus, Cnaphalocrocis medinalis granulosis virus
corn, soybeans, rice, canola, vegetables, turf and more. On corn, farmers
Protozoon Nosema locustae can reduce their N fertility program 27% and achieve standard yields OR
maintain their N fertility program and reach 5-20% yield increases. Envita
Gene-edited
Bacillus thuringiensis strain G033A and N-Fix are critical components of a sustainable nitrogen management
microorganism
plan for agriculture.
Chilo suppressalis sex pheromone, Spodoptera litura sex pheromone, Apolygus lucorum sex pheromone,
Semiochemical
Grapholitha molesta sex pheromone, Carpocapsa pomonella sex pheromone
Gibberellic acid, Gibberellic acid A4+A7, heteroauxin, indolebutyric acid, enadenine, oxyenadenine, benayl
Natural plant growth
aminopurine, 24-epbrassinolide, 14-hydroxylated brassinosteroid, triacontanol, abscisic acid, ascorbic acid, kinetin,
regulator
iron chlorine e6, allantoin, etc.
Biochemical
pesticide
Natural insect growth
(Z)-9-Tricosene, (S)-Methoprene
regulator
Natural plant elicitor Harpin protein, plant activator protein, oligosaccharins, lentinan, chitosan, oligosaccharide, mixed fatty acids, etc.
Other Cholecal ciferol
Matrine, camphor, rotenone, azadirachtin, veratramine, pyrethrin, nicotine, celastrus angulatus, eucalyptol, star
anise oil, chamaejasmine, triptolide, curcumenol, cnidium lactone, eugenol, physcion, carvacrol, berberine,
Botanical pesticide
androstanol, tea saponin, TDS, allicin, d-Limonene, terpene alcohol, allyl isothiocyanide, ginkgo seed extract,
Fructus psoraleae seed extract, Banda de Lupinus albus doce
Insecticide Abamectin, spinosad, ivermectin

We invite leading agribusiness companies to
express interest in licensee or master distributor
Agricultural Rodenticide Botulinkum type D, botulinkum type C
antibiotics opportunities across Europe, South America and
Bactericide and fungicide
Validamycin, kasugamycin, polyoxins, pyrimidine nucleotide bacteriophage, ningnanmycin, Phenazino-1-
carboxylic acid, Zhongshengmycin, tetramycin
Southeast Asia.
（Active ingredients in blue are exempt from Maximum Residue Level (MRL). Source: ICAMA） www.envita-uk.com
Envita™ is a trademark of Azotic North America Ltd. N-Fix® is a registered trademark of Azotic Technologies Ltd.
Products and Technologies Products and Technologies
normally degrades much more quickly and becomes ineffective after one or
two weeks. However, if the Biorational products can be applied in a more
Greening up the Future of

sophisticated way through drip irrigation on a regular (e.g. weekly) basis,
that weakness of shorter lasting efficacy suddenly becomes a positive aspect,
as these will deliver no residues or less long-lasting residues in the soil. This
may be a very positive trend that will continue to expand and provide a good
Our Food Production impetus for further developments.

Methods of spraying a crop sufficiently thoroughly for a contact-acting
product to be fully effective are already being worked on, but this remains an
issue and more work is needed to achieve good enough coverage especially in
By Jan Mostert, Head of Biorationals Innovation Team at Certis Europe
broad-acre open field crops. However, it may also be possible to find solutions
to control pest or disease attack on plants by using different cropping systems.
Taking an example of change from history in the top fruit sector, we can see
that apple or pear trees are now much smaller and more closely spaced than
they were 20 years ago. This has allowed more cost-effective production of
these fruits through the use of automated harvest systems. It has also allowed
Much has been written about the aims and objectives of the development in biorationals and has become a leading player in the sector and
for better spray coverage, less spray wastage and therefore less impact on the
EU Farm to Fork and Biodiversity strategies and the need for the in the development of new biorational products.
environment, while control has improved. We might need to think a bit more
targets set therein for a “greener and healthier agriculture” system The European crop protection market is estimated at €16 billion, of
‘outside the box’ to develop different innovative cropping systems that will
to be “science-based, technically feasible and economically which 6% is bio products. The bio market has been growing at around 15%
make it possible to use more optimal spraying techniques, making biorational
sustainable” for all those involved in the food supply chain. The per annum. Due to political drivers like the Farm to Fork strategy and the EU
sprays more successful through good contact and full coverage, while still
EU Commission agreed that this will require serious investment Green Deal, that growth is expected to be at least maintained so that by 2030
delivering an economically viable yield.
in research and development. biologicals could represent 15% of the market. Certis currently has biorational
It would be a huge advantage if biorationals had systemic effects, but few
Certis Europe has for many years been focusing on the crop protection product sales in all sectors (speciality crops, potatoes, arable
do. We continue to look for products that can be used in outdoor crops, last
greening and expansion of its product portfolio using science- and seed treatment) amounting to an 8% share of the total bio market. To keep
long enough to be comparable to conventional products and that are acceptable
based research to deliver technically sound, sustainable and the Certis biorational portfolio growing at market speed, Certis is investing
to growers’ practice. There is some light at the end of the tunnel: we do have
economically viable solutions in support of growers and for 35% of its innovation and development budget in new Biorational product
actives that can do the job and are almost as strong as conventionals for open
the benefit of consumers. Very much in tune with the new EU development this year.
field crops, but they are currently some years from the market and of course
strategies, the company continues to invest in research and Substantial progress has been made in Europe over the last 20 years in terms
there may be regulatory restrictions that will prevent or limit their use. At least problems in the full range of crops, so we need each other, and
of reducing pesticide usage and developing viable alternative solutions for the
we are trying. some competition is healthy, driving innovation to the next level.
control of pests and diseases. Biologicals (biorationals and biostimulants) have
Clearly there is still space for competitors, who have great products to bring Between us perhaps we can green up the world, as the politicians
brought about dramatic changes to crop protection in speciality crops, largely
to market. No one company can provide the whole package for all diseases and want, to make it a better, safer place with more biodiversity.
in protected conditions, and, though it is true that more and more products can
now be positioned in open field crops, the issue of achieving acceptable levels
of control of target pests or diseases with existing products has not yet been
resolved. Developing biorational sustainable solutions for open field crops is
a high priority for the company and fits perfectly with the European Green
Deal and its Farm to Fork strategy. It is not simply a matter of transferring a
product and application technology from the greenhouse to outdoor situations.
Biorational solutions are generally not long-lasting, are seldom rain-fast and The Certis Europe Biorationals Innovation Team of dedicated experts and its research
offer no systemic activity. Climate, the environment and the cropping system centres focus on the evaluation of potential new products. This year they are evaluating 26 candidate
must also be factored in and here the accumulated experience and expertise of products, a balance of fungicides and insecticides, from 16 different suppliers. Of these, six products
the Certis team is invaluable. have come through from last year’s candidates for further testing and possible development. On
Trending changes in crop management, very much in line with climate average only half survive after the first year of trials for review in the second year. The decision to
change responses, can offer new opportunities for Biorationals to become used continue investing in the product and develop it further or not is normally taken after the second year. In
more. For example, in these times of global warming and fresh water scarcity, 2021 the team will run more than 160 screening trials.
high value open field crops that offer a reasonable return on investment, such as One product that has successfully come through this process is Problad, a novel, broad-spectrum biorational
fruit, vegetables, vines and even potatoes, are increasingly making use of drip- fungicide for use in both protected and open field cropping. First registration is expected in the EU in 2022 with others to follow.
irrigation. We are already seeing evidence of increased use of drip irrigation A new active substance of natural origin and a new fungicide class FRAC BM01, it has a unique, multiple mode of action and is
in potatoes in more northerly countries such as the Netherlands and the UK, to exempt from Maximum Residue Level (MRL). It is highly effective against many plant pathogens like Botrytis , Powdery mildew,
reduce water usage and wastage. Many biorational products for the control of Monilia and Rice blast and authorization is initially expected for use in tomato, strawberry, vines, stone fruit and rice. A range of
soil pests like nematodes, wireworm or fungi can be soil applied. The efficacy other crops will be added at a second stage.
of strong conventional products can last many weeks, whereas a biorational

Another major benefit of using PREV-AM is the synergy it provides when Oro Agri’s continuous quest for scientific knowledge
PREV-AM® the 3-in-1 Insecticide, Fungicide

using it with other types of plant protection products and plant protection drives us to invest heavily in plant science and plant protection
techniques. Insecticides, acaricides, fungicides, biological controls (using research. This research has shown the greatest value of PREV-
endogenous population or the release of specific beneficials), and bio-technical AM, while highly effective as a stand-alone application, is
and Miticide, Problem-solver with Minimal programs will be greatly enhanced by the unique properties of OROWET®
technology and the orange oil active ingredient mode of action contained in
optimized when its quick knockdown, physical mode of action
and reduced chance of resistance is used in synergy with other
PREV-AM. active ingredients and/or biological controls. It also has been
Environmental Impact For example, one popular approach in France has been to spray both PREV-
AM and reduced rates of sulphur in a tank-mix. Universities and independent
proven that regular use of PREV-AM as part of a regular spray
program provides great economic return by knocking down pests
studies have shown PREV-AM and sulphur combinations, when sulphur populations before they reach the damage threshold that might
was reduced by as much as 50%, provided at least a 30% improvement in require more expensive and resistance-susceptible pesticide
disease control when compared to sulphur applied at full rates as a stand- applications.
Agriculture has always been demanding, but PREV-AM provides effective alone treatment. PREV-AM has shown to be more curative and sulphur more Farmers will continue to face agronomic, societal, and
nowadays growers are facing a multitude of new protection against a wide range preventative, and when these products are sprayed in combination throughout environmental pressures as they strive to produce a healthy
factors directly impacting their activities and of insect, mite, and disease the early season, not only is powdery mildew controlled, but also downy food supply. But now with PREV-AM they have an important
requiring them to constantly adapt to meet these new targets with a minimal impact on mildew, early incidence of Botrytis , and also insects such as mites, leafhoppers, tool to address many of the most pressing of issues these like
challenges. beneficial fauna. aphids, and mealy bugs. resistance management, pesticide residues and food safety and
Climate change, consumer health, worker The quick breakdown of sustainability.
protection, society’s image of agriculture, new PREV-AM, with no residual
pest pressures, pesticide resistance management, activity, minimizes its effect on About ORO AGRI
loss of active ingredients, and the need to support beneficial and non-target species.
biodiversity are challenges growers are confronted Moreover, PREV-AM weakens ORO AGRI develops and manufactures patented products
with daily. the target pests, making them for agricultural, home, and industrial applications worldwide.
Farmers are very adept at evolving and adapting more vulnerable to predators and We specialize in products that provide effective yet residue-free
best practices to become more efficient and parasites. Independent studies solutions to our clients’ pest control challenges. ORO AGRI
sustainable, but they also need help from industry have proven that under high pest develops, and distributes a portfolio of products that includes
partners to meet these on-going challenges. They rely pressure an application of PREV- biopesticides, adjuvants, soil conditioners, bio stimulants, foliar
on new products from crop protection manufacturers AM will quickly knock down the pest population and create a positive predator/prey ratio. fertilizers, and postharvest products. We are present in more than
to meet their goals of increasing yields while Beneficial insects are critical to the economic and ecological health of agro-ecosystems. 90 countries, having factories on four continents, and state-of-
producing healthy food with little or no pesticides Establishing an equilibrium where beneficials can control pests to the point the economic the-art science and research centers in Brazil, Europe, the U.S.A.,
residues, all while being grown with farm worker damage threshold is not reached and extensive pesticide treatments are not needed is a long and South Africa.
and environmental safety as a top priority. term, expensive and arduous goal to achieve. A single mis-applied or incorrect pesticide Our research database contains more than 2000 field trial
That is why a new era for nature-based, low- application can jeopardize years of best practices by upsetting this delicate balance. However, studies, including contributions from over 500 universities
environmental impact products, with innovative PREV-AM, because of its low impact on beneficial insects offers outstanding efficacy against and research consulting groups. This research has led to over
mode of actions, is upon us. One contribution damaging pests while keeping the predator/prey relationship in sync. 200 patent applications, 22 patents, 68 biopesticide product
from Oro Agri, PREV-AM (also sold under brands PREV-AM is a great tool to manage pesticide resistance by offering an registration certificates, more than 100 pending registration
OROGANIC®, PREV-GOLD®, OROCIDE®) is a alternative and complementary mode of action to synthetic chemicals When certificates, and over 1500 granted applications for various
multipurpose biopesticide utilizing a proprietary included in a resistance management spray program it increases treatment trademarks and slogans.
blend of botanical compounds found in cold- efficiency, optimizes the number of applications per season allowed for ORO AGRI investment in innovation and R&D combines
pressed orange oil. It is a contact pesticide conventional pesticides and extends the useful life of resistance-susceptible science with natural and renewable resources to create safe and
solution against a wide variety of insects, diseases, plant protection partners. The physical mode of action of PREV-AM greatly environmentally friendly crop protection and yield improvement
and mites. An application of PREV-AM provides reduces resistance development so it can be applied without seasonal limits solutions for the global agricultural and consumer markets. At its
protection against these three pest threats at and can help clean up resistant pest populations not controlled by other active core, ORO AGRI has always been science powered by nature!
the same time, which is a unique characteristic ingredients.
among other pesticides on the market. PREV- The immediate knockdown and curative effect of PREV-AM can Web: www.oroagri.eu
AM provides broad-spectrum protection in open significantly improve pest control when tank mixed with partners with residual Information: [email protected]
field and greenhouse conditions for both organic activity or used with other pesticides applied at low end labelled rates. Its
and conventional farming operations. It helps patented orange oil active ingredient combined with OROWET technology,
meet growers’ goals with an effective biopesticide with its excellent surfactant properties, will dissolve honeydew and clean up
exempt form MRL tolerances and greatly sooty mold to improve control of pests hiding in the honeydew. Because of
reduced worker and environment safety concerns the synergy of the different modes of action, tank mixes with PREV-AM often
compared to conventional chemical pesticides. show a 30-70% improvement versus applications without PREV-AM. Source: ORO AGRI

How do biostimulants work? include;

- Balance between longer lasting humic acids, and quick acting
Biostimulation, from Novel

fulvic acids
Biostimulants have the capability to trigger and improve the ability of - Use of recognised and well-studied raw materials such as
crops to naturally resist abiotic stress effects. In essence, with or without American Leonardite
biostimulants, the crop will alter its metabolism to respond to an abiotic - Products approved for Organic Agriculture by OMRI are
Technology to a Must in Agriculture stress. However, the use of biostimulants on crops allows for a quicker,
more effective and /or more efficient response by the crop.
available
There are a variety of sources that may have biostimulant properties, Amino acids: Vegenergy, Delfan and Aton ranges
and they differ in their origin and / or their modes of action within the
plant. In general, biostimulants can be allocated to one of seven groups: Tradecorp’s range of amino acids is based on free L-α amino
humic / fulvic acids, protein hydrolysates (e.g. amino acids), seaweed acids, which are key to recover crops during or after an intense stress
extracts, chitosan, inorganic compounds, beneficial fungi and period. Factors to consider about amino acids include;
In recent years climate change has gone from being a probability to becoming a reality that determines, beneficial bacteria (du Jardin 2015). These diverse sources are still being - Only free L-α amino acids are 100% biologically active
for better or worse, our daily lives. As a consequence, climate change and climate breakdown have become fully explored and understood, and are yielding a steady stream of new - L-α amino acids have a beneficial nutrient carrier effect
a priority problem that is influencing agricultural production worldwide, for example by affecting rainfall innovations and products for agriculture. - Animal or vegetal sources available
patterns, temperature, and even seasonal patterns. Increasing knowledge about the mode of action of each biostimulant is - Products approved for Organic Agriculture are available
Traditionally farmers and growers considered variables such as the time of year, seeds, fertilisers, plant now enabling growers to make the best decision about which biostimulant - Excellent Tank Mix properties
protection and soil management, among others. However, in recent years “new” challenges have emerged, to choose, when to apply it and what dosage to use. By understanding the
particularly linked to climate change. These newer challenges mean that to achieve a crops’ full potential, mode of action, growers can now know what beneficial effect is expected Seaweeds: Phylgreen range
traditional plant nutrition and plant protection practices are no longer sufficient. from that particular biostimulant application (Brown & Saa 2015). All of
Cathal Daynes These external, non-pathogenic and non-biological challenges are known collectively as non-living this new information is benefiting the grower’s decision making. Seaweed biostimulants come in many different shapes and forms.
Global Technical Manager in stresses or abiotic stress . Today management of these abiotic stresses is one of the principal topics of Tradecorp´s Phylgreen range is specifically designed to prevent
Tradecorp discussion, and research, in agriculture. It is widely accepted that if abiotic stress could be well managed abiotic stress in crop by applying the product before the onset of
there is the potential to go a long way towards increasing global food production by the 50% needed by What are the best options to prevent abiotic stress.
2050, and achieving this necessity in a more sustainable fashion. However, this will be no easy challenge… and mitigate abiotic stress? - Exclusive Primactive effect
- Based on pure Ascophyllum nodosum seaweed extract
- Fresh sourced raw material from sustainable harvesting
Abiotic stress management with biostimulants When dealing with abiotic stress, choosing the most appropriate - Unique Gentle Extraction method, which naturally preserves the
product, the right application time, and the best method of application biostimulating compounds present in the fresh seaweed (polyphenols,
is not always an easy task. For optimal results, product knowhow, and mannitol, alginates, etc.)
One of the most promising areas of research in abiotic stress management is biostimulation of plants. its correct inclusion in agronomic strategies are key to ensuring that the - Products approved for Organic Agriculture are available
When applied appropriately, biostimulants have been demonstrated to effectively reduce the impact of maximum effect and return on investment are achieved. In a new sector
abiotic stress on crops, helping them to achieve their full yield and quality potential. such as biostimulants, this is a lot of new knowledge to assimilate. Botanical extracts: Vegecore range
In recent years, the use of biostimulants has been recognised as a good agricultural practice, assisting Tradecorp have been focusing on presenting, and making available in
agriculture to become more sustainable and even more environmentally friendly. In fact biostimulants have other formats, these recent advances in agronomic knowledge to growers Natural solutions to promote root and plant growth derived from
such potential in abiotic stress management in agriculture that this “new” industry has grown rapidly from an as easy to understand concepts, and information, to empower them to plant origin.
insignificant size ten years ago, to today where it is estimated to be worth around $2.3 billion (2020) and to make best use of this rapidly evolving technology in their agronomic - Obtained from renewable and sustainably grown plants
reach more than $4 billion in 2023. The rapid and continued growth of this market is farmer driven as they programs. - High in fulvic acids, which strongly promote root and plant
have been quick to recognise the benefits these products bring to their crop… and their bottom line. growth
A plant “biostimulant” in agriculture, according to the definition in the European Union fertiliser Humics: Humistar/Humifirst range - Recommended for root application, also suitable for foliar
regulations, is a product that stimulates plant nutrition and growth processes independently of the supply
product’s nutritional content. Biostimulants have the sole aim of improving one or more of the following Humic acids provide a complete improvement of soil fertility via - Slightly acid pH for high compatibility with other agricultural
characteristics of the plant, or the plant rhizosphere (root zone): a positive effect on the physical characteristics (structure), chemical products
• nutrient use efficiency characteristics (greater availability and recycling of nutrients), and - Increases beneficial soil microbial activity
• tolerance to abiotic stress biological characteristics (increased microbial life) of soil by;
• quality traits - Enhancing root elongation and secondary root development
• availability of confined nutrients in soil or rhizosphere - Integral improvement of chemical and physical soil conditions
While biostimulation has been demonstrated to effectively reduce the impact of abiotic stress on crops, - Increasing soil microbial populations
an important point about them is that they have no specific effect on pathogens or pests. Thus, to control - Increasing fertiliser use efficiency
these biotic challenges, plant protection products will still be needed. Other factors to consider in decision making regarding humic acids

Did you know that…
disasters such as
drought
Idai Nature, France Launches
PORTENTO® to Eliminate Fungi for Good
extreme
and
temperatures
PORTENTO® is a biological fungicide based on a new generation
strain of Bacillus subtilis
• The product prevents and cures fungi, acting as a shield against the
proliferation of diseases in the plant.
• It eliminates Scab in pome fruit trees, Powdery Mildew in cucurbits and
Downy Mildew in lettuce and related plants.
have nearly quadrupled since 2010 vs the 1970s1?
Phytosanitary product is approved in France under the registration number AMM:
2200311.
The Bacillus subtilis strain contained in PORTENTO® has several action
mechanisms. On the one hand, once applied in the field, it secretes secondary metabolites
with a direct fungicidal action. As a healing solution, PORTENTO® is capable of rapidly
generating a large number of antimicrobial metabolites that effectively destroy the cell
membranes of phytopathogenic fungi.
On the other hand, it limits the implantation of pathogenic microorganisms by
competing for space and nutrients and it induces the activation of the plant’s self-defence
system (SRI/SAR), thus also having a preventive effect.
It should be noted that it is a completely harmless naturally sourced product, which
does not generate residues or resistance in crops and respects secondary fauna.
New generation strain
The Bacillus subtilis strain in PORTENTO® is a new generation strain, with greater
Biostimulants demonstrably help prevent or reduce the impact fungicidal capacity than other strains and other types of Bacillus . This comes from the
of these abiotic stresses on crops, helping them to achieve Amaya Jordá optimal balance of the 3 main secondary metabolites (Iturins, Fengycins and Surfactins).
their maximum potential yield, quality and profitability. Portfolio Manager The balance provided by these three metabolites is responsible for the greatest fungicidal
capacity.
Tradecorp offer a complete and differentiated portfolio Active forms of Bacillus quickly reach their maximum development, generating
of biostimulants including humic acids, amino acids, seaweeds a high concentration of secondary metabolites, thanks to their rapid development and
and botanical extracts to effectively manage unwanted growth rate. As a result, a very powerful and differentiated biological tool is obtained
which makes the difference in terms of effectiveness.
abiotic stress effects.
This strain can grow under more unfavourable conditions, increasing its capacity for
success, and has a greater tolerance to stress from environmental conditions. Moreover,
unlike other Bacillus -based products, PORTENTO® has a very short pre-harvest safety
period: 0-1 days.
Lastly, it should be noted that PORTENTO® has low application dosages, it is
suitable for zero residue strategies, it does not require special storage conditions and it is
compatible with 95% of copper and sulphur-based products.
Learn more at:

www.tradecorp.com.es
1- FAO, The impact of disasters and crises on agriculture and food security, 2021.
In honor of our celebration of 20 years • We will provide a deeper focus on our customers, partners, and growers, that
of growth, we are excited to announce our sustainability that will drive our internal, means continued support in the products
The Global Expansion of Certis Biologicals rebranding from Certis USA to Certis
Biologicals, a global manufacturer and
external and product research and
development decisions.
that they know and love, along with the
opportunity to join us as we scale.
distributor of biological products that will • We will continue to scale globally, as
meet the needs of partners and growers we expand our international portfolio with Featured Global Products:
throughout the world. We are committed our high-quality production and multiple
to leadership in the industry, sustainability, manufacturing facilities available to our
Since the early development of biological innovation, manufacturing, and marketing of partnerships within the market, and we global expansion, advancements in growers around the world.
and botanical biopesticides, Certis has been bio-based solutions in commercial agriculture continue to push the boundaries of what’s technology, and new product development. • We will maintain strong brand
part of the industry’s growth. We began as and the home and garden markets. technologically possible in the agriculture As Certis Biologicals continues to expand alignment as a highly technical & innovative Amylo-X® WG is a broad-spectrum
an innovator aimed at developing sustainable Decades ago, we planted our seeds industry. As the importance of biologicals in into international markets: competitor in the market as we differentiate preventive biofungicide for control or
crop protection products to solve grower within the development of Bt biologicals agriculture grows, we continue to thrive in • We have a clear vision in developing ourselves and communicate our expertise in suppression of over 90 fungal and bacterial
challenges, generate new opportunities, with a vision of creating more sustainable developing new, sustainable technologies, biological solutions that add value to the biologicals space. plant diseases.
and improve existing processes to meet the agricultural practices at a state-of-the-art finding innovative ways to combat pests to conventional practices with our simple, As Certis Biologicals, we will continue to
market’s ever-evolving needs. With innovation fermentation facility in Wasco, California. protect crops, and leading the industry as a compatible, and efficient technical ingredients expand our international portfolio to supply
at the forefront, we have become the leader of We took root and grew as Certis USA through whole. with growers’ needs in mind. products to customers across the globe. For
Agree® WG is a powerful biological

insecticide specific for use against the
lepidopterous larvae listed on the label
and won’t harm beneficial insects that help
eliminate worms that crawl into crops.
Delfin® WG contains a naturally

occurring Bt kurstaki strain that offers broad-
spectrum control of mixed worm populations
in tree and vegetable crops.
We are proud to announce our global

expansion due to our visionary leadership,
collaboration with trusted partners, and the
willingness to strive harder every day to grow
internally and externally. As we commit to
growing relationships internationally, we will
support sustainable practices in our business
processes, our resources, and our products.
We are Certis Biologicals, born with a
broader focus to bring biological leadership
and solutions to partners and growers in
countries across the globe. We didn’t invent
biologicals; we made them what they are
today. We welcome you to join us as we
continue to lead and grow.
For more information, visit certisbio.com.
Source: Certis Biologicals

they may cause the precipitation of insoluble agricultural practice is constantly growing. of glycinate reaches the phloem, glycine is
sediments, which clog the sprayer nozzles AMINO ULTRA® is a group of recognized by plants as valuable nitrogen
Fertilizers for New Challenges making the perform of treatment impossible.

Binding micronutrients with organic
components – chelating or complexing agents
micronutrient foliar fertilizers based on
glycine, amino acid naturally occurring in
plant and organic chelating agent. Although,
compound and then molecule is quickly
transported inside the plant cells. Inside the
plant cells enzymes break down the bounds,
such as: synthetic chelating agents (e.g., all amino acids can be used as ligands, the separating ligand from the nutrient and then
EDTA, DTPA), lignosulfonates, humic and most preferable are those with the lowest nutrient can be utilized by plants.
In the recent years, we have observed significant changes in plant production technologies, which fulvic acids, organic acids (e.g., citric acid) molecular weight. Glycine is the smallest and AMINO ULTRA® fertilizer line is
first and foremost are aimed at increasing efficiency of plant cultivation. The expectations of agricultural and amino acids (e.g., glycine) is an effective the most mobile amino acid. Its molecules are consisted of four products: AMINO ULTRA®
producers regarding these technologies are much further than obtaining high yield. More and more attention way of increasing nutrient stability in solution almost four times smaller than the chelating Cu-24 (containing 24% of Cu), AMINO
is paid to increasing yield quality and agricultural practices carried out in accordance with environmentally and preventing their high reactivity. Synthetic molecules used in standard micronutrient ULTRA® Fe-20 (containing 20% of Fe),
friendly procedures. chelates, such as ETDA, DTPA have been chelates. Therefore, glycine creates small AMINO ULTRA® Mn-22 (containing 22%
Nowadays, modern agriculture uses new, high yielding cultivars with an increased demand for used in agricultural practice for around 50 molecules with metal (called glycinates) Mn) and AMINO ULTRA® Zn-24 (containing
micronutrients, which should be provided easily and efficiently. Micronutrients are required by plants in years. However, nowadays micronutrient which pass through the leaf pore (stomata and 24% of Zn). Each of them contain around
PhD Anna Konieczny low amounts but have a significant effect on yield quantity and quality. In addition to high demands for fertilizers where amino acids are used instead ectodesma) more easily than larger particles 30% of glycine. They are produced in an
International Marketing Manager, micronutrients of new cultivars, also intensive plant cultivation, increased NPK fertilization, cultivation of synthetic chelating agents are gaining of standard synthetic chelates, thus improving ultra-granulate form, what makes them
INTERMAG in poor soils, limited use of natural fertilizers make increasing effectiveness of micronutrient application more and more popularity. These fertilizers, the efficiency of micronutrient absorption convenient for handling – no dust, no caking.
particularly important. Farmers around the world are struggling with difficult growing conditions such as: frequently called aminochelates or amino through leaves. After absorption through AMINO ULTRA® are quickly and totally
long and severe droughts, large temperature fluctuations, frosts. These factors cause significant decrease in acid chelate fertilizers are created by binding the leaf the small molecule of glycinate soluble in water and can be mixed with
production profitability, very often because of insufficient plant nutrition during the periods of increased nutrient (either macro or micronutrient) with easily penetrates the leaf. The unique feature other agrochemicals after carrying out the
plant demand for nutrients. Foliar feeding is the most effective way of precise nutrient supply to plants one or more amino acid (mainly glycine). The of glycinates, is the fact that, contrary to compatibility test. High concentration of
especially under conditions of limited nutrient uptake from soil due to soil properties (e.g. low or high pH) high efficiency in providing nutrient to plants synthetic chelates, both nutrient and organic nutrients, around 60% more than in standard
or unfavourable growing conditions (drought, low soil temperature) as well as in plant growth stages with and relatively low risk of phytotoxicity cause ligand are utilized by plants and have a EDTA chelates, allows for lowering the doses
high demand for particular nutrients. Micronutrients applied via foliar spraying are utilized much faster than that the interest in using aminochelates in beneficial effect on plants. When the molecule of AMINO ULTRA® per 1 ha compared to
micronutrients uptaken from soil. Moreover, the availability of most micronutrients in the soil decreases
with increasing soil pH, what additionally strengthens the importance of foliar feeding. The effectiveness
Radoslaw Wilk
of foliar feeding depends on many factors such as agrotechnical and weather conditions, plant species and
Product Manager - Fertilizers,
plant growing stage. Regardless of these factors, the type of fertilizer or rather the form of nutrient provided
INTERMAG
to plants via foliar spraying plays a significant role in the absorption and utilization of nutrients. Therefore,
form of nutrient used in the fertilizer is a key factor determining its effectiveness.
Chemical salts are one of the types of fertilizers used for foliar application. However, instability of
free Cu, Fe, Mn, Zn cations in solution and their high reactivity with other components of working solution
significantly limits their availability for plants what decreases the effectiveness of applied fertilizers. Also,

Products and Technologies
EDTA chelates. This decreases the

cost of micronutrient fertilization
while maintaining optimal level of
plant nutrition.
The effectiveness of AMINO
ULTRA® has been confirmed by
many studies and field trials. The
results proved that AMINO ULTRA®,
applied via foliar spraying are
quicker and more efficiently absorbed
than standard fertilizing chelates.
Thanks to the use of glycine, natural
chelating agent, plant absorb nutrients A group of extremely specialised regulatory
quickly and effectively even in harsh experts with knowledge of the EU as well
environmental conditions. Moreover, environment. as worldwide regulations and requirements
it was observed that foliar application Farmers are looking for the new solutions which in difficult growing conditions, recently occurring in place.
of glycinates is more “safe” for more and more frequently, will allow them to increase profitability of agricultural production. AMINO
For Agrochemicals Manufacturers whishing to:
plants compared to standard chelates. ULTRA® with very high concentration of nutrients, quick and effective nutrient availability for plants,
• prepare for new challenges with the EU
AMINO ULTRA® fertilizers are low dose per hectare and application safety for plants and environment are fertilizers which help
Fertiliser Products Regulation
environmentally friendly. Glycine farmers to meet those challenges. AMINO ULTRA® is a perfect solution in plant nutrition even in harsh
is rapidly biodegradable in the
• proactivelly use time still available to generate
environmental conditions.
registrations
environment, therefore the technology
is not only safe for plant but also for AMINO ULTRA® is a registered trademark of INTERMAG.
• understand regulatory situation currently in
place for fertilisers
• expand their markets
OUR NETWORK IS YOUR

NET WORTH
The Fertiliser Consultants Network offers
regulatory support:
• with fertilisers and their placing on the market
• with biostimulants, basic substances,
agricultural additives and biologicals in
general
• in many EU Member States and some
countries beyond the EU (North Africa,
South America, Russia, lndia and China)
www.fertcon.net / [email protected]

MAAVi Innovation Center: The botrana and Cydia pomonella. However, most field crops, citrus and cherries, as well as our
Alternative to Synthetic Chemicals of our attention and resources are focused biostimulant platform, which is already at an
Deep Diving into Biological Dark Matter 45 projects are currently being researched
at MAAVi Innovation Center, all of which
on another species, Spodoptera sp., which
affects 66 different crops, primarily soybean
in Brazil and corn in China, and has an annual
advanced stage of development.
Additionally, we are involved in
developing seed treatments with biostimulant,
cover major issues for global agriculture. economic impact of about 1.2 billion dollars. biopesticide, and probiotic solutions, as well
They are classified in three different areas: We are also developing biofungicides to as other new approaches such as the use of
Biocontrol, Plant Performance, and Pre- & combat pathogens like Botrytis cinera in vine, bacteriophages as biological agents against
Probiotics. which has a huge impact on both vineyards devastating diseases like Erwinia amylovora
Southern Europe is home to the world's greatest biotechnology center for natural After two years of extensive research, in and table grape crops in France, Italy, in pome fruit trees.
agriculture. From there, a group of experts is working on over 45 current projects to September 2020, we announced the status of Spain, China, USA, Chile, and Australia. We also run MAAVi Labs, which are
address the major challenges confronting global agriculture, as well as assisting other our bioherbicide platform, a project that will Similarly, we are targeting coffee rust and strategic partnerships with agribusiness
agribusiness companies and producers in becoming "greener". result in a natural alternative to glyphosate, the devastating black sigatoka of bananas companies and large producers in which we
Efrén Remesal González, Director of Research & Development, tells us about their developed with the help of various omics in Central America, for which there is no make our research center available to them to
history and future projects. tools capable of identifying molecules and treatment yet. These pathogens urgently need assist them in customizing their own natural
natural compounds with phytotoxic activity a natural, effective solution, and therefore solutions.
for the development of a new generation of clearly deserve a dedicated project.
bioherbicides. In terms of agricultural environmental It’s all about natural efficacy
Efrén Remesal González Almost at the same time, our natural sustainability, we are now working on
Director of Research & Development at MAAVi Innovation Center substitute for hydrogen cyanamide began its identifying a specific consortium of The efficacy of our products is based
agronomic validation phase. With similar microorganisms for the phyllosphere, which on our 4Health Technology, which follows
results to its chemical counterpart, but with will benefit the crop by fixing atmospheric pharmaceutical industry procedures, assisted
no risks to the health of the applicator. nitrogen, biostimulating the crop, and by a proprietary artificial intelligence
Producers of deciduous fruit trees now have a increasing production. algorithm. This enables us to uncover non-
natural alternative to offset the climate change Furthermore, we are studying specialized obvious realities within the synergistic
induced cut in the number of chill hours, microbial consortia for soybean and relationships of the compounds we
Just over 14 years ago, Kimitec’s there, they began to travel around, trying to regarding growth and protection. which are essential for sprouting. tomato, which will ultimately increase obtain from four natural sources: Botany,
founders set out to change the way food is identify the latest scientific and technological But let us continue our story. The But we have many other projects in the the organoleptic and chemopreventive Microbiology, Microalgae and Green
produced. developments and meet the brightest minds in European Union launched its Green Deal pipeline. characteristics of fruits. Chemistry.
At the time, scientific evidence was the emerging, brand-new field of agricultural plan in May 2020, right in the middle of In the realm of insecticide-based And finally, let me mention our plant It is worth noting that just 0,2% of
beginning to point to agrochemicals as the bioscience. the worldwide COVID 19 crisis, which biopesticides, we are working on a solution performance area, which is not only searching those bioactive compounds, also known by
cause of biodiversity loss, water pollution, They discovered that nature (plants, featured a specialized program for the agri- against many species of lepidoptera , and on for the aforementioned substitute for hydrogen the scientific community as “nature’s dark
and other serious environmental and human fungi, bacteria, and microalgae) is an endless food sector: From Farm to Fork. Growers a second one against nematodes. The first cyanamide, but also for other solutions such matter”, have been identified. As a result, our
health concerns. In Europe, large distributors source of bioactive compounds, capable of throughout Europe became pallid. How project focuses on Tuta absoluta , Lobesia as a solar protectant for horticultural open- Machine Learning system will significantly
set out on a quest to limit the use of active naturally increasing agricultural productivity. were they supposed to maintain productivity, increase and expand our knowledge about
ingredients, imposing MRLs that were often After investing over 20 million euros while reducing chemical-based agricultural the plants, microorganisms, and microalgae
stricter than applicable regulations. And in the research and development of natural inputs by 50%, fertilizers by 20%, and with which we are working, helping us in
consumers, a key piece in the entire food agricultural solutions and demonstrating that nutrient losses by at least 50% while increasing the productivity of our MAAVi
production system, were feeling completely the development of natural biopesticides, as ensuring no deterioration on soil fertility. Innovation Center, minimizing the time
outraged at the multiple scandals involving effective as their chemical counterparts, was The United States, Canada, China, and South to develop natural and effective tools, and
the toxicity of agricultural inputs that made indeed possible, in October 2019 Kimitec Korea quickly followed suit. Taking action reducing the rate of error in our research
the front pages. opened its MAAVi Innovation Center, the against climate change was imperative, and activities.
The founders of this biotechnology largest research center for biopesticides and environmentally friendly measures were high As you can see, technology is at the
company were convinced that there was probiotics dedicated to natural agriculture in on everyone’s political agenda. core of our business. But we only use it to
another way, a different approach based on Europe, and one of the largest biotechnology We immediately understood how hard highlight nature’s leading role. The sooner
the elimination of synthetic molecules from hubs in the world. those measures would hit European growers, we unveil and understand the links between
our food production system. And they decided A state-of-the-art facility of over 5,000 leaving them without real, effective tools to nature's many systems in general, and crops
to take action. They would offer farmers an m2, with a greenhouse area of 1,000 m2, sustain productivity and face a potentially in particular, the sooner we will attain the
alternative: Natural solutions as effective as managed by an R&D&I team of over 50 serious problem of pathogen resistance. We environmentally sustainable, healthier future
synthetic chemicals. industry experts, who currently work on the realized that we needed to accelerate and we desire.
Kimitec’s headquarters is located in the development of nature-based solutions, trying expand our research model. Remember, nature has the answers… We
heart of Europe's agricultural hub. From to understand the needs of every crop, both just need to find them.

Challenges of Bio Market in for seed treatments and/or fungicides, as the range is wide
and powerful.
But on the other hand, the preservation of these products
Argentina; Agri Star Adds M2i

is not a minor issue. Many of them still have six-month
conservation periods, they are temperature-controlled and
intolerant to variations in weather conditions. That is when
Pheromones into Package

companies have to take that into account as well.
The last point, which is the collaborative link between
public and private levels corresponds to the regulatory
part. These products are new for everyone and those who
impart the regulations for their registration are in the
same situation, working in an unknown world. This issue
will have to be addressed in a way that is different from
conventional products, otherwise, there will be bottlenecks.
There are millions of solutions, but only a dozen approved
for use.
From Agri Star, with the developments that have begun,
several new ones have been added to the product pipeline.
Currently, the Organic Fungicide Problad is being
tested. It is a biological insecticide for ants, an endophyte, or
an organic insecticide. Work will begin with a nematicide,
a fertilizer and we will strengthen the already existing
cooperation with M2i Life Sciences, the European Leader
of Biocontrol through pheromones to build strong synergy
Turning to the sustainable and the biological, Agri Star started the touch load more between an Argentine company leader in the intensive
than ten years ago. AgroPages reports the cooperation between Certis US, CEV S.A. and cultivation market and a French company leader in the
Agri Star, as the company continues to bring and commercialize biological products to the production of pheromones.
Argentina market. As Eng. Ezequiel Nardini, said, “It is the right way to go and Agri Star has
contributed in satisfying the organic and low-residue market demand.”
When talking about Biopesticides, pheromones are the cornerstone

of the new biocontrol toolbox. That is why M2i, a leading company
in pheromones for biological plant protection has been marketing and
testing biological crop protection solutions in Argentina for several years.
While the registration files for pheromone mating disruption against
grapevine moth, codling moth and oriental fruit moth were submitted
For a few years now, traditional agricultural input companies have been turning to
between end-2019 and mid-2020, M2i has decided to consolidate its
sustainable agriculture over time. And we know it is the right way to go.
local presence by creating a subsidiary. M2i Biocontrol Argentina,
They began by discontinuing molecules that were risky in their toxicological band that
founded in February 2020, will manage the sales of M2i products in
affected humans and the environment and even their manipulation was very complex.
close cooperation with Agri Star.
Today, with a narrower portfolio of products (developments are very expensive and
This joint structure, in addition to managing M2i's product portfolio
patents last very little) companies have begun to work on biological/organic solutions. Shared
in trapping and agricultural monitoring and holding its marketing
expectations from growers, consumers, and public opinion have accelerated the situation.
authorizations, will manage their commercial relationships with M2i’s
However, companies are going at a pace that is faster than what it takes the producer
global partners such as Syngenta (a distributor of pheromone for
to adapt to these new paradigms and products. It is a great challenge but at the same time a
Eng. Ezequiel Nardini, grapevine moth, to be marketed soon).
great opportunity for companies to add real value to the product if its advantages are properly
Commercial manager at Agri Star Along with those and with the continued development in the
communicated.
company, Agri Star is being positioned as a benchmark of biologics in
However, three important product points must not be neglected. Regulatory issues,
intensive crops in Argentina.
Efficacy and finally Shelf life.
Starting with efficacy, we are seeing many companies that aim to develop products that
have the same or higher efficacy than a conventional agrochemical. They hoped to combat
various pests of importance with systems of sexual confusion, consortia of microorganisms

underlying this behavior are identified (Could be the molecule itself, or byproducts of the molecule´s This study was performed with ATCC
production?) strains of the fungi species Beauveria
(ii) Biocompatible – and then separated as: bassiana , Trichoderma harzianium ,
Biosolutions at OXITENO: Capabilities and

(ii.i) highly compatible – can be applied as a carrier or in encapsulation methods. However, and bacteria species B. subtilis, B.
the formulator must be careful as these molecules (gums and some vegetable oils, for instance) can amyloliquefaciens , B. firmus , Pseudomonas
be consumed as carbon source by the microbes, which can lead to a microbial development within chlororaphis , and compatibility assessed
Technologies for the Biopesticide Market the package under certain conditions. Oxiteno has a unique line of green solvents based on raw
materials of renewable and waste source of the agroindustry, specific for microbial formulations and
during their entire lifecycle.
These microbes were chosen based on
background to indicate the better use of these products for a higher shelf life. relevance on the market and representing
(ii.i) compatible at certain concentrations – here the challenge is to identify the minimum different metabolic/physiological,
inhibitory concentration of the molecule and target it as the maximum to be applied in a formulation. morphological and physicochemical models.
They can be applied as emulsifiers, dispersants and co-dispersants based on raw material waste This background allowed to propose the
and renewable source. Besides these examples, Oxiteno has a broader portfolio for microbial design of new chemistries and innovative
Biologicals are here to stay! Microbial products don’t leave pesticides residues in the crops. formulations. strategies of formulation to work specifically
formulations use in the field grow above any Indeed, biological residues are suitable for the soil An example of how Oxiteno has worked with each component is given on Figure 1. with microbes and have been the basis of
other segment in agriculture. Having an incredible microbiota, improving fertility. Oxiteno’s current innovation project pipeline.
growth rate by 13.68% and stands out in the The biocompatibility of the products is the It allows not only the indication of the
main crops such as soybean, corn and sugarcane, first step to provide a toolbox of components for most suitable components for customer´s
expected to reach close to USD 20.59 billion by the formulator. Oxiteno published a review of the application, but the development of tailor-
2026 [1]. From 2010 on, biologicals entered as main methods to start a microbial formulation [2], made solutions for the market.
Poliana Cardoso-Gustavson disease and insects crop management tools for row also providing a new methodology for the fast Microbial formulations require additional
R&D Scientist for Crop crops, which was an important milestone for this and low-cost quantification of microbes on leaves, cautious besides the usual physicochemical
Solutions in Oxiteno market consolidation. Biologicals are expected to validated and published by ASTM. This study challenges, such as the integrity of
be a common tool in the integrated management resulted from a robust study analyzing 50 different extracellular matrix, electrolytes, final pH,
of farmers globally in the next decade. chemistries of our portfolio, aiming to understand inert filler, etc. All these components must
Oxiteno has been positioned in the market how different molecules interact with different be formulated to guarantee that the microbe
with targeted biopesticides (living microbes microbes and identify the limitations of the will be kept in the dormant/inactive stage
and their metabolites, and other biostimulants). different chemistries to be applied on each microbe during storage and only start developing after
In Biosolutions Innovation Platform, Oxiteno model. From this study, we identified molecules application on the right target. It’s important
works in the development of special components and their functionalization that are suitable for to keep in mind that the performance of a
for bioprocesses, and formulations of microbes microbial formulations, and developed skills to formulation applied in a hydrophilic culture
and metabolites as biopesticides, and dsRNA. In design the preferential chemistries to be applied as media is different from the substrate where
Biosolutions, and more specifically to biopesticide dispersants, wetting agents, emulsifiers, or carriers to the microbes will grow up in the field, which
Henrique Alves are mainly hydrophobic in nature (aerial part
formulations, Oxiteno has worked on generating better address the challenges of formulators.
Field Marketing for Crop of the plant and root systems).
knowledge and internal capabilities to become In general, the main causes of the loss of
Solutions in Oxiteno To achieve the better performance from
a solution provider since 2017 and has now viability of microbes in a formulation are the
reached a state that enables product development, air, water (humidity) and direct interaction with the microbe strain, tank mix and in-can
robust technical positioning and co-creation surfactants. Regardless of the best compatibility of formulations cases were studied to identify
with our partners and customers. With a team of some surfactant, a long time of direct exposure with the causes of viability loss and how to
specialists and a complete structure of Research microbes will lead to a harmful interaction with cells’ overcome them.
and Development, Oxiteno works alongside structures, thus decreasing shelf life. The formulation In-can formulations with a suitable shelf
the industry to develop customized solutions strategy here is how to delay these interactions by life can be achieved keeping the microbial
according to these special active ingredients and choosing the right molecules, including purification cells apart from the fermentation debris
application modals. In addition to a biological steps to avoid some by processes of its production and water. Package properties will decrease
laboratory, the company's R&D Center in São whenever necessary. In this sense, the bioassay the interaction with air and a proper protection
Paulo/Brazil has capabilities to develop and test must be performed with components applied on of the microbes by means of a suitable carrier
new technologies. Oxiteno has consistently worked the culture media with parameters evaluated during or encapsulation is desirable to improve
with microorganisms to understand which products different stages of the microbial development, thus shelf life. Oxiteno has developed production
can be applied safely and effectively, as well as providing reliable results and information about how processes [3] and products specifically for
how to formulate them to provide products and the products will interact with microbes. In summary, WDG formulations, and solutions for SC
solutions for tank mix and in-can formulations. the answers from the study are split into: formulations of both bacteria and fungi
The use of microorganisms contributes immensely (i) Incompatible – the molecule leads the species.
to the sustainability of agriculture, as biological microbes to viability loss, and the reasons For tank mix, four main factors must be

Products and Technologies DISRUPTION MANAGMENT • TRANSITION MANAGEMENT • EXECUTIVE SEARCH
considered for a successful application of a bio-AI: (i) pH of the final solution, (ii) time in hours
from the tank mix preparation until application, (iii) concentration of all the products in the
Oxiteno has structured capabilities
to formulate microbes: a complete and
“Their experience;
tank, (iv) addition order of the components in the tank. After considering these factors, it’s possible dedicated laboratory of microbiology, willingness to understand
to design the right compatibilization products with chemical AI, and other bio-based AI as well. library of microorganisms, microscopes, our organisation, and
the long term commitment
Oxiteno relies on its own capabilities for development, besides projects with partners for flow cytometer, besides laminar flow hoods
greenhouse and field trials for data generation and validation. and usual microbiology equipment. To
better target microbial performance, it can with customers provided us
be performed applications on leaves using
the spray chamber to study the influence
with the right partner.”
of different nozzles in the application of
microbes, as well as to assess rainfastness
Claudio Torres
resistance of the formulations. For better Global CEO, Advanta Seeds (2015)
results, the applied plants are grown in a
growth chamber where conditions such as
temperature and humidity are controlled.
To increase capacity, the construction of a
greenhouse for the cultivation of plants used
in tests is ongoing. Seed treatment coverages
and germination trials are performed in
Crop Solutions lab. Rhizotron root trials
using target-plants are developed to assess
the performance of the prototypes in seed
treatment and in-furrow applications using
different soil sources. Besides morphometry,
plant physiological features are assessed
with Oxiteno’s infrared gas analyzer
combined with a fluorometer to assess the
improvements in plant performance promoted
by microbes.
Count on Oxiteno’s background,
capabilities and people to the development
of your microbial-containing formulations.
For more information, please reach
[email protected].
We understand
what your talent needs are.
Specialists in Agribusiness
References
[1] Fortune Business Insights™ 20. Agriculture Biologicals Market Size.
[2] Cardoso-Gustavson P et al. 2020. An introduction of techniques to aid in building microbial-containing formulations: from the selection of components
to foliage application. Pesticide Formulation and Delivery Systems (ASTM International): 40: 104-127.
[3] Cardoso-Gustavson P et al. IP-pending. BR 10 2020 0246771. Formulation of water-dispersible granules containing microbiological actives and
preparation method.
W W W. L I M L O G E S M A S T E R S . C O M | C O N TA C T @ L L M R E C R U I T. C O M
CHINA • HONG KONG • INDIA • SINGAPORE

Physical properties for AltaBio offerings Environmental safety and UV protection
Ingevity’s AltaBio portfolio currently consists of eight product Unlike synthetic naphthalene sulfonate formaldehyde condensate
grades, all with high purity levels and low salt content, shown in Table 1. (NSF) based dispersants, AltaBio derived from sustainable processes
Ingevity’s New Generation of Table 1. Physical properties of AltaBio product portfolio

making it safe to use with various microorganisms, including
Burkholderia cepacian , Rhizobium leguminosarum , Bacillus megaterium ,
Trichoderma reesei , Bacillus thuringiensis , Bacillus subtilis , Beauveria
Sustainable Dispersants Meets bassiana . As shown in Figure 2, no zone of inhibition was observed
on a lawn of microbes treated with AtlaBio products, while the NSF-
the Complex Challenges of based dispersant showed a clear zone of inhibition when incubated with
Bacillus thuringiensis .
Biological Formulations
*EPA 4B; neutral pH and higher Mw options are available if being requested
To determine the appropriate AltaBio grade for specific formulations, Figure 2. Inhibition tests of AltaBio products and a NSF-based dispersant
Ingevity recommends formulators consider both the degree of sulfonation on Beauveria bassiana and Bacillus thuringiensis
In recent years, the increasingly stringent regulations for conventional pesticides coupled (DOS) and molecular weight. The DOS characterizes the extent of
with consumers’ growing preferences to eat organically have expanded the need for “biological sulfonation. For example, AltaBio 40, 50 and 55 products have a high
pesticides,” or biopesticides, derived from natural materials1. Based on the U.S. Environmental DOS, meaning they are more hydrophilic. Alternatively, AltaBio 60, 150 Specific bacteria, fungi and viruses can provide effective pest control
Protection Agency’s (EPA) definition, there are two main groups of biopesticides, including and 200 products have a low DOS, so they work better with hydrophobic when sprayed onto plants. However, these microbes are rapidly degraded
naturally occurring substances known as biochemical pesticides, and microorganisms known as surfaces. Since the main stabilization mechanism for lignosulfonate is by sunlight, which limits their field efficacy. AltaBio combats the
microbial pesticides. steric stabilization, the higher molecular weight results in better steric degradation by providing additional UV protection to various biological
Formulating microorganisms into stable products is particularly challenging due to the delicate stabilization. For example, Beauveria bassiana is known to be very spores, such as Bacillus megaterium , seen in Figure 3. However, since it
Guigui Wan nature of these living organisms. Additionally, some microorganisms are ultraviolet (UV) sensitive, hydrophobic and difficult to suspend in water. AltaBio 200 would excel is a highly active dependent, the UV protection must be further evaluated
Technical Team Lead, requiring extra effort to maintain viability under field conditions. in that specific formulation due to its low DOS and high molecular for use in other biological species.
Agrochemicals, Ingevity For large-scale production of microorganisms, a process known as industrial fermentation is weight, providing increased affinity to the hydrophobic surfaces and
commonly used. This process generates many side products including toxins, proteins and other strong steric stabilization for long-term formulation stability.
metabolites, further increasing the complexity of the biopesticide formulation. Among the eight available products, AltaBio 40, 60, 4082W and
To solve these challenges, pine-based chemistry provider Ingevity continues to innovate and 6082W are included on the U.S. EPA’s 4B list for organic pesticide
develop high-performing agricultural co-formulants made almost exclusively from renewable formulations.
resources. The newest line of next generation kraft lignosulfonate dispersants, AltaBio™, is AltaBio 4082W and AltaBio 6082W have built-in wetting agents and
designed specifically for challenging microorganism formulations, including wettable powder (WP), can be used to wet hydrophobic spores without the need of an additional
water dispersible granules (WDG) and suspension concentrates (SC). wetting agent (see Figure 1).
Compared to Ingevity’s legacy Reax® and Polyfon® kraft dispersants, the company leveraged its
unique processing capabilities for improved purity and performance to create the AltaBio dispersant
Gift Metavarayuth product line. These high-performing dispersants are safe with various microorganism species and
Senior Formulation Chemist, offer increased suspensibility and wettability compared to alternative sulfite lignosulfonates and
Agrochemicals, Ingevity various synthetic dispersants (i.e. naphthalene sulfonate formaldehyde condensate and styrene
acrylic-based dispersants). Figure 3. UV protection of AltaBio to Bacillus megaterium.
By combining performance and environmental safety, AltaBio performs efficaciously with the
flexibility of minimal application restrictions and superior resistance management potential.
AltaBio outperforms alternative dispersants for Beauveria

bassiana
To compare the performance of AltaBio to alternative dispersants, the

Figure 1. AltaBio 4082W provides excellent wetting to hydrophobic challenging biological active Beauveria bassiana was formulated into WP
1. Transparency Market Research; Biopesticides Global Industry Analysis, Value, Share, Growth, Trends, and Forecast Report, 2019 – 2027; https://www.
Beauveria bassiana spores. using various dispersants including three Ingevity kraft lignosulfonates
transparencymarketresearch.com/report-toc/116.

(AltaBio 200, PolyFon F and Reax 910), two naphthalene sulfonate formaldehyde Table 4. Beauveria bassiana WDG formulation recipe
condensates, a styrene acrylic-based dispersant, and two sulfite lignosulfonate dispersants.
The detailed recipe is shown in Table 2.
Table 2. Beauveria bassiana WP (10%) formulation recipe
The WP formulations were dispersed thoroughly in water, then particle size and
suspensibility of each formulation were measured.
Compared to other dispersants, two formulations that contained kraft lignosulfonates
resulted in smaller particle size of D50, and less conidia aggregates, as shown by D90. The
smaller particle size at D50 and less aggregation suggest improved coverage of AltaBio
on the conidia surface, resulting in higher suspensibility of the formulation at 86.4%.
Additionally, when compared within the kraft lignosulfonate group, higher MW dispersants
Figure 4. Beauveria bassiana WDG appearance.
perform better than the lower MW counterpart. This observation proposes steric hindrance
as one of the stabilize mechanism in these formulations.
Table 3. Properties of Beauveria bassiana WP formulations with different dispersant
Figure 5. Beauveria bassiana WDG upon wetted in

water (left). Beauveria bassiana WDG dispersed in
water (1%) after 30 minutes left undisturbed (right).
Achieve high performing formulations with

Ingevity’s ultrapure dispersant, AltaBio
With ultrahigh purity and enhanced molecular

*Overestimated suspensibility value observed here likely resulted from higher quantity of weight, AltaBio provides excellent coverage for
unwetted conidia floating on the suspension surface.
microbiological actives, leading to high-performing
WP and WDG formulations. With more than 90%
AltaBio 200 performance in Beauveria bassiana WDG formulation bio-derived content, AltaBio has excellent safety,
suspensibility and wettability properties and prove to
Based on the prescreening result detailed above, Beauveria bassiana WDG was be extremely safe with various microorganisms.
successfully prepared using AltaBio 200 with detailed recipe shown in Table 4. Ingevity’s agrochemicals technical team can help
The formulation above produces porous granules that disintegrate easily in water customers utilize the key advantages of these co-
and provide suspension with small particle size ~4µm at D50 and ~17µm at D90. The formulants by offering confidential, complimentary
small particle size at D50 and D90 indicate very minimal conidia aggregation upon water co-development of difficult formulations. Through
dispersion. ongoing technical support and seminars, Ingevity
The WDG formulation proved to be very stable when subjected to freeze/thaw can share new data and advice for formulating
conditions, as shown by the preserved disintegration property with small particle size with dispersants, adjuvants, solvents and other co-
growth to ~4.5µm at D50 and ~20µm at D90. formulants.

BREAK-THRU® additives were tank-mixed with

biopesticides based on different microbial actives
in several field trials, including: RootShield®AG by
Evonik BREAK-THRU® Additives Applied Tank-Side Bioworks (Trichoderma harzianium ), DoubleNickel™

LC (Bacillus amyloliquefaciens ) by Certis and
in Field Trials to Enhance Efficacy of Biopesticides Nemat® (Paecilomyes lilacinus ) by Ballagro (Figures
2, 3 and 4). No phytotoxicity to the crop was observed
in any of these trials.
Evonik conducted a strawberry field trial in
North Carolina to test the influence of BREAK-
THRU® additives on the performance of RootShield®
AG against Botrytis and Pythium . The biopesticide
RootShield® AG contains Trichoderma harzianium
and is labeled for the control of Botrytis rot (gray
mold) and Pythium spp. Botrytis is a common pest
of strawberries in most years occurring in the field,
during storage and transit, of strawberry fruit (Frank
Louws, 2018). Pythium is a common disease in North
Carolina and is the main reason growers fumigate
Marc A. McPherson, Ph. D. Dr. Daniela Kruse
in the southeastern US region. The disease reaches
Agronomist, Specialty Additives, Director New Markets, Interface &
a peak at harvest with reductions of crop yield up
Interface & Performance at Evonik Performance at Evonik
to 20 to 40%. Early damage from Pythium causes
plant stunting that is apparent within 1-2 months
after planting (Louws and Cline, 2019). BREAK-
THRU® S 233 and BREAK-THRU® S 255 with
The use of formulated microbes in agriculture has THRU® S 233 are biodegradable, patented and OMRI listed organomodified the high dose rate of RootShield® AG significantly
increased in the last years primarily driven by consumer trisiloxanes. BREAK-THRU® S 301 is a super spreader and provides wetting of the reduced the incidence of Pythium (on roots at harvest)
preference for reduced use of chemical pesticides and upper and lower side of leaf surfaces, increases deposition, adhesion and stomatal and Botrytis (on fruit at harvest) relative to the high
grower need for new modes of action to control resistant flooding. BREAK-THRU® S 233 reduces surface tension and aids in deposition, rate of RootShield® AG alone. In addition, the root Figure 2. Disease incidences and root vigor from a field trial with RootShield® AG at
pests. One barrier to adopting biological products, especially adhesion and penetration. BREAK-THRU® S 255 and BREAK-THRU® OE 446 are vigor at harvest was significantly increased relative two different dose rates with and without BREAK-THRU® additives. Field trial in North
live microorganisms, is the low or inconsistent efficacy organomodified polysiloxanes, which are soluble in both water and oils, providing to the high rate of RootShield® AG alone suggesting Carolina with strawberries in plots that were 1.8 m x 9.1 m in a randomized complete
relative to conventional pesticides. rain fastness. BREAK-THRU® OE 446 is OMRI listed. For application of biologicals reduced nematode damage block design with four replicates. RootShield® AG was applied five times with drip
Evonik has shared research on biocompatible additives in soil, BREAK-THRU® S 301, BREAK-THRU® S 233, BREAK-THRU® S 255 and (Figure 2). irrigation. AUDPC is area under the disease progression curve. Pythium disease rating
that can be used within formulations to increase the shelf BREAK-THRU® OE 446 provide homogenous wetting and distribution of actives in Evonik conducted a bell pepper field trial in North were conducted on roots at harvest on a scale from 0 to 10, with 0 indicating no disease
life and enable liquid formulations in Agropages in 2019. the soil. Carolina to test the influence of BREAK-THRU® present and 10 all roots with some Pythium disease present. Root vigor was rated on a
In this article, Evonik will share field trial results to additives on the performance of DoubleNickle™ scale from 0 to 10 scale with 10 being the best.
demonstrate the performance enhancement of biopesticides (Bacillus amyloliquefaciens ) against bacterial
with tank-side adjuvants. spot (Xanthomonas spp.). Bacterial spot is caused
For a microbial product to be effective and economical, by four Gram-negative aerobic bacterial species
it is essential that the organism is deposited and retained (X. euvesicatoria , X. gardneri , X. perforans , and
on the intended target and survives to have the desired X. vesicatoria ) and occurs worldwide. It causes
effect. The fate of spray droplets delivered from agriculture leaf and fruit spots, which cause defoliation, sun-
equipment is complicated and includes drift, bounce-off scalded fruit, and yield reduction. Management of the
and run-off. Additives can be used to reduce these issues disease needs to be preventive because once a field
(Figure 1) but must not negatively affect microorganism becomes infested, bacterial spot is difficult to control,
viability. Research at Evonik has demonstrated that many especially when the environment is conducive to the
of the BREAK-THRU® additives are biocompatible disease (Scherer et al., 2019). BREAK-THRU® S 301
and provide excellent wetting, deposition, adhesion Figure 1. The possible fates of spray droplets for foliar applied crop protection numerically improved the incidence of bacterial leaf
and retention for foliar applied biopesticides. BREAK- products. This is a highly complex process affected by droplet size, droplet velocity, spot with the low rate of DoubleNickle™ relative to Figure 3. Disease incidence from a field trial with DoubleNickel™ at two different dose
THRU® SP 133 is a biobased and biodegradable, OMRI wettability of the plant surface, plant surface roughness and surface tension of the the active alone. BREAK-THRU® S 301 statistically rates with and without BREAK-THRU additives. Field trial in North Carolina with bell
and FIBL listed polyglycerol ester that can reduce formulation. Once droplets leave the nozzle, smaller droplets are prone to drift, while reduced bacterial leaf spot incidence with the high pepper in plots that were 1.8 m x 2.7 m in a randomized complete block design with six
drift and increases adhesion and retention of foliar larger droplets can land on the intended target and then either adhere or bounce off or rate of DoubleNickel™ relative to the active alone replicates. DoubleNickle™ was foliar applied with a flat fan nozzle six times. Bacterial
applied products. BREAK-THRU® S 301 and BREAK- run-off. (Figure 3). leaf spot was rated as a percentage of plants in each plot where the disease was present.

Evonik conducted a soybean field trial in

Brazil in the Bandeirantes region of the State
of Mato Grosso do Sul to test the BREAK-
THRU® additives on the performance of
Nemat® (Paecilomyes lilacinus ) against
nematodes (Pratylenchus zeae , Pratylenchus
brachyurus , Helicotylenchus spp., Heterodra
spp.). Nematodes cause plant damage but
also create entry points for other pathogens,
and act as vectors for viruses, bacteria and
fungi. Control methods against nematodes
have limited efficacy because they have
difficult to penetrate cuticles, which enables
the resistance to physical and chemical
agents (Alcanfor et al. 2001). BREAK-
THRU® SP 133, BREAK-THRU® S 301
and BREAK-THRU® OE 446 statistically
improved plant height 30 days after the fifth
application (DAE) suggesting nematodes Figure 4. Growth and yield from a field trial with Nemat® at two different dose rates with and
were suppressed more in those treatments. without BREAK-THRU® additives. Field trial in Brazil with soybean in plots that were 6 rows (0.45
BREAK-THRU® SP 133, BREAK- m) x 5.0 m = 13.5 m2 in a randomized complete block design with four replicates. Nemat® was
THRU® S 301 and BREAK-THRU® OE 446 foliar applied with a flat fan nozzle six times.
applied at the low rate of the Nemat®
statistically improved yield relative to the low Summary
rate of the active alone (Figure 4). Nematodes Field trials with commercial biopesticides from three different companies demonstrates
of all species were numerically and often enhanced efficacy and no phytotoxicity with tankside addition of BREAK-THRU®. The commercial
significantly lower with the use of the three biopesticides were based on three different microbial species: Trichoderma harzianum, Bacillus
adjuvants than the active alone at the same amyloliquefaciens and Paecilomyces lilacinus. One limiting factor of adoption of microbial based
rate (data not shown). products is low efficacy and Evonik BREAK-THRU® products can be part of the solution.
References:
1.Alcanfor, DC, Inneco, R, Corales, JS, Mattos, SH. 2001. Controle de nematóides de galhas com produtos naturais. Horticultura Brasileira, v. 19.
2.Frank Louws. April 12, 2018. North Carolina Extension. Botrytis Fruit Rot / Gray Mold on Strawberry.
3.Frank Louws and Bill Cline. Aug 19, 2019. North Carolina Extension. Black Rot of Strawberry.
4.Scherer A, I Meadows, and Michelle Henson. 2019. https://content.ces.ncsu.edu/bacterial-spot-of-pepper-and-tomato. North Carolina Extension
document.

Products and Technologies
In this work, more than 60 co-formulants or adjuvants were microorganism strains are activated and germinate, upon formulation
evaluated to assess their impact on the viability of four key dilution and application.
Solvay: Enhanced Adjuvants

microorganisms either beneficial fungi or bacteria, among which
two biofungicides (Bacillus subtilis (CCT0089), Trichoderma
harzianum (CCT4790)) and two bioinsecticides (Bacillus thuringiensis
& Co-formulants Toolbox for (CCT2335), Beauveria bassiana (CCT3161)).

The selection of co-formulants was made, based on the
functionality they can bring to the targeted microbial biopesticide, the
Monique Adamy
Solvay Novecare Agricultural
Microbial Biopesticides relevant formulation type, EPA NOP regulation compliance criteria for
some of them, and no or low hazards considerations. The compatibility
with the four microorganisms strains was investigated at several
Specialties R&D Lab Manager,
concentrations of adjuvants, from 1 to 5% (w/w) in water via zone of
Europe.
inhibition tests, an adapted agar disk-diffusion methodology (Balouiri
et al. 2016)2: six blank disks of 6mm of diameter, saturated with each Figure 1. Zone of inhibition tests with Bacillus thuringiensis: left side,
adjuvant solution were placed in a petri dish previously inoculated adjuvant with no negative impact on microorganism growth; right side,
Through the use of living organisms, natural substances or semiochemicals, biopesticides with 0.5ml of microorganism’s cells. Water and hydrogen peroxide adjuvant with significant inhibition on microorganism growth. *The
prevent or reduce damage from pests and pathogens, emerging as one of the most promising (50%) were used as positive and negative control respectively. If the bottom right disk in both plates represents the positive control (water),
tools for sustainable agriculture. They complement the use and reduce the risk of resistance co-formulant inhibited the growth or killed the microorganisms, the therefore, no inhibition was expected.
to synthetic agrochemical actives, thus strengthening integrated pest management (IPM) radial length of the inhibition zone around the disk was measured.
adoption. Growth drivers include consumer demand for organic and residue-free food, increased This methodology aims at anticipating potential viability issues, once Table 1 shows an extraction of results obtained for 20 co-formulants:
environmental, biodiversity and health concerns with some conventional pesticides, associated
with a rising regulatory pressure on agrochemicals. In this context, European Union’s Farm to
Fork strategy and the Brazil National Bio-Input Program set clear targets to favor this transition
Ling Qi Table 1. Zone of inhibition test, compatibility of co-formulants with 4 microorganisms
towards mitigation of conventional agrochemicals usage. Among biological control (Biocontrol)
Solvay Novecare Agricultural
agents, the use of beneficial microorganisms represent more than 58% of the total market share Microbial Viability (Zone Inhibition Test)
Specialties R&D Scientist
of biopesticides1.
NOP / Bacillus Trichoderma
However, the global rate of adoption of microbial Biocontrol based solutions remains Function
Product Name OMRI
GHS
EPA Bacillus subtilis Beauveria bassiana
(Formulation type) Classification thuringiensis harzianum
(SC,FS,WP,WDG) (OD,WP,WDG )
relatively low in comparison with conventional pesticides, with often less consistent biological Eligibility* (SC,FS,WP,WDG) (OD,WP,WDG )
efficacy reported in the field, in adverse conditions. Classical root causes analysis include
Rhodasurt® 860/P No No if < 1% 180.910&180.920 (1%) (1%)
lack of stability of the product during storage, less active material reaching the target and
EU: No if < 2.5%
rapid degradation of the biopesticide once applied related to environmental factors. In this Rhodasurt® CET/5 Yes 180.910&180.920 (1%)
UN: No if < 1%
context, optimized formulation strategies are a key lever to enhance global bioefficacy of such Soprophor® BSU Yes No if < 25% 180.910&180.920
biopesticides. Soprophor® 4D-384 Yes No if < 25% 180.920
Adequate co-formulant selection is especially vital as it can lead to: Soprophor® FL/K Yes No classification 180.920
• Improved shelf life, with enhanced microorganisms viability Soprophor® 796/P No No classification 180.960
Wetting Dispersing
Fernanda Barreto Costa • Satisfactory wetting & homogeneous dispersion upon formulation dilution without Agents Antarox® 25-R-2 and L-62 Yes No classification 180.960
(WP/WDG/SC/FS)
Solvay Novecare Agricultural agglomeration (no nozzles blocking etc.) Antarox® PL 104 Yes No classification 180.940&180.960
Specialties R&D Lab Manager, • Spray droplet size control for optimal coverage (foliar & soil) Antarox® PLG-254 Yes No classification 180.960
Latin America. • Improved wetting, adhesion, humectancy and rainfastness on target Antarox® B 600 No No if <= 4.2% 180.960
• Improved viability/survival rate of microorganism coated on seed Geropon® DA 1349 Yes No classification 180.960
Geropon® T 36 Yes No if < 18% 180.910&180.920

• Increased microbial activity against targeted pests and pathogens, and improved
Supragil® RM/210-EI Yes No classification 180.910&180.920
bioavailability of beneficial metabolites
Geronol® CF82 CC Yes No classification 180.920
There is however no universal solution for microbial biopesticides formulation: each
Alkamuls® T20 Yes No classification 180.910&180.920
beneficial microorganism species has different sensitivities to chemicals, water, temperature,
Emulsifiers Alkamuls® OL 40 Yes No classification 180.910&180.920
environmental factors such as UV, drought and humidity. Depending on the mode of action (OD, EC) Alkamuls® RC Yes No classification 180.960
of the microbial biopesticide and the surface targeted, the functionalities required for the final
Alkamuls® VO 2003 No No classification 180.960 nt nt (1%)
formulation may vary considerably, involving for instance the need for adjuvants bringing
Retention & rainfastness AgRHEA™ SticGuard Yes No classification 180.950
rainfastness, humectancy, increased wetting & solubilization. For Bacillus subtilis or B.
amyloliquefaciens biopesticides for example, the selection of co-formulants is crucial to achieve no inhibition zone with 1% or 5% adjuvant;
Marina Pessoa a good bioavailability and improve the solubilization of the lipopeptides cocktail produced by slight inhibition with 5% adjuvant, no inhibition with 1% adjuvant;
Solvay Industrial the bacteria during the fermentation process, for an adequate antifungal activity. Additionally, significant inhibition observed at 1 and 5% adjuvant (radius inhibition zone [2 - 11mm]);
Biotechnology Laboratory, the specific strains and fermentation processes can have a substantial impact on final broth nt: not tested
R&D Researcher composition, impacting formulation methodology and biological performance. *compliant with EPA’s National Organic Program (NOP): CAS# under List 4A or List 4B, thus OMRI eligible

Interestingly, Soprophor® BSU, 4D/384 and 796/P grades, Antarox® based on guar gum, is presented: the microorganisms were separately the disease intensity was calculated in % of the total area of the leaf In summary, thanks to the multi-disciplinary approach of
25-R-2, L-62 EO/PO copolymers, Antarox® B600, Supragil® RM/210- inoculated in the experimental broth containing 1% (w/v) of AgRHEA™ analyzed. The biological efficacies were determined from the AUDPC3 microbiology, phys-chem, and agro formulation expertises, a series of
EI & Geropon® T36 which are wetting or dispersing agents for wettable SticGuard and the control media (without AgRHEA™ SticGuard). All values, expressed in % vs untreated control. co-formulants/adjuvants were identified as interesting candidates for
powders (WP), Water Dispersible Granules (WDG) or Suspension flasks were incubated at 30°C, 150 rpm, for 96h, with sampling every As shown in Figure 3, compared with the control (without adjuvant the formulation design of microbial pesticides. A natural biodegradable
Concentrates/Flowable Concentrates (SC/FS), display a good biological 24h for colony counting or dry weight measurements. The growth rate addition) and the commercial benchmark, AgRHEA™ SticGuard not polymer AgRHEA™ SticGuard was evidenced to bring both bioefficacy
compatibility with tested microorganisms strains. For B. bassiana , was calculated and compared with control experiments. As shown on only promoted a better efficacy in absence of rain (from 12 to 22%), enhancement and rainfastness improvement on microorganisms.
which needs typically to be formulated in a water-free medium such as Figure 2, in presence of 1% (w/v) of AgRHEA™ SticGuard, a significant but also revealed a more important “synergetic boosting” effect in Additional technologies within the SOLVAY toolbox are also
a vegetable Oil Dispersion (OD) to keep the fungal conidia in dormant increase of microbial growth was observed for all microorganisms tested, presence of mild rain (20 mm). This effect is considered to be related available to solve for example wetting/agglomeration/aggregation issues
state for a suitable shelf-life, Alkamuls® T20, RC or OL 40 are good indicating a viability enhancing effect. to the moisture-facilitated growth of Bacillus amyloliquefaciens or a observed with microorganisms & their metabolites upon dilution. For on-
emulsifiers options. The improvement of retention and rainfastness with AgRHEA™ redistribution of the product by the rain. Furthermore, under heavier seed application of biologicals, AgRHO® BIOBINDER microplastic-free
Geronol® Odessa 01, a versatile ready-to-use vegetable oil dispersion SticGuard was further investigated through bioefficacy trials, in rain simulation (40 mm), the biological efficacy of the reference system binder solutions or AgRHO® S-Boost biostimulants range for synergistic
basis, containing emulsifier & dispersant system, as well as rheology collaboration with BIOTRANSFER research service company. A without adjuvant was annihilated, probably related to the complete wash- combination with microorganisms are technologies that pave the way for
modifier for adequate stabilization, is also a particularly interesting commercial biofungicide based on a strain of Bacillus amyloliquefaciens off of the biopesticide solution, while it was exceptionally well retained enhanced biological efficacy in a sustainable way.
formulation solution for B. bassiana or T. harzianum fungi. was applied at a rate of 2.5kg/ha (300L/ha spray volume) with/without in presence of adjuvants, especially with AgRHEA™ SticGuard.
After this first biocompatibility assessment, specific adjuvants were AgRHEA™ SticGuard at a dosage of 0.07% (w/v) or with a commercial
further tested to determine if they could favor microorganism growth synthetic latex at 0.1% (w/v) on grapevine leaves, with 6 replicates
upon dilution, and finally, application and efficacy trials were conducted. for each series. An artificial rain of 20mm or 40mm was then applied
In the following example, a microbial growth study in presence of for some samples, prior to inoculation with calibrated suspension (105 References
AgRHEA™ SticGuard, a natural retention and rainfastness agent spores/ml) of Botrytis cinerea strain. 4 & 6 days after inoculation, [1] Agrow Biopesticides, 2019
[2] Balouiri M, Sadiki M, Ibnsouda SK 2016. Methods for in vitro evaluation antimicrobial activity: A review. J Pharm Biomed Anal. 6(2): 71-79.
[3] AUDPC: Area Under Disease Progress Curve, Madden et al. 2007.
Growth rate relative increase in presence of AgRHEA™ SticGuard vs. control
Bacillus subtilis CCT0089(10^10 CFU/gr) 136%
Bacillus subtilis CCT0089(10^6 CFU/gr) 112%
Bacillus amyloliquefaciens CCT7690 (10^5

108%
CFU/gr)
Bacillus thuringiensis CCT2335(10^5 CFU/gr) 117%
Beauveria bassiana 129%
Trichoderma harzianum 244%
0% 50% 100% 150% 200% 250%
Figure 2. Relative increase of bacteria or fungi growth rate with AgRHEA™ SticGuard.
No rain 20mm rain 40mm rain

60%
52%
48%
41%
34%
40%
Bioefficacy
23%
22%
13%
20%
12%
0%
0%
Bacillus Amyl. WDG Bacillus Amyl. WDG + Bacillus Amyl. WDG +

(Control) AgRHEA™ SticGuard Commercial Benchmark
Figure 3. Adjuvant effect on biological efficacy of a commercial WDG Bacillus amyloliquefaciens with/without 2
rainwashing amounts (20mm, 40mm)

“This is a huge step forward. Until now,

modern environmental-controlled glasshouses
have typically had a single static sensor -
recording climatic parameters. OKO is a
Biobest Embraces AI to Help

dynamic sensor, recording precision data
regarding temperature, relative humidity,
CO2 concentration, light intensity etcetera
throughout the glasshouse - creating a high-
Growers Drive up Yields resolution map for each parameter.”

He goes on to explain, “All this data can
be layered on top of each other to provide
answers to questions such as, how fast will
a particular crop pest develop and in which
direction - to inform decision-making.”
Digitization of IPM
To empower growers and boost yields of high-value crops, global IPM and substrate pH. intelligence, algorithms, predictive analytics precision growing will be the next big
and pollination specialist Biobest has joined forces with ecoation to drive AI- “Data-driven growers constantly measure these parameters “Ecoation technology allows for the and decision support systems. revolution in horticulture. “Growers will be
optimised IPM in Europe and is partnering Arugga AI Farming to distribute to keep a grip on plant growth – using it to steer vegetative or digitization of the IPM workflow. OKO “Supplying all of this, OKO also has the managing at a plant, rather than a crop, level,”
pollination robots in North America. generative growth – optimising crop yields. provides an essential tool for the rapid potential to provide yield predictions and can he says. “We are entering a new era involving
30 years ago, Roland De Jonghe of Biobest pioneered the commercial “Growers base their decisions mostly on ‘gut feeling’ information gathering and knowledge objectively assess the quality of crop work, the integrated use of cameras, decision-
production of bumblebees and their use for pollinating greenhouse tomatoes – and experience and their ‘reading’ of plants,” says Karel. distribution necessary for timely optimization such as fruit picking. These are powerful support systems and analytically tools - big
not only setting off a revolution in crop pollination but providing an early driver “In the Netherlands, we have the Autonomous Greenhouse of biological control strategies. additional tools. In short, OKO informs changes are coming.”
for biological control and integrated pest management (IPM). Fast forward three Competition – an annual event which sees leading growers “At Biobest we set out to provide ‘best integrated crop management and integrated OKO will initially be launched in
decades and the company he founded – Biobest – is a global leader in both areas. pitted against AI to make crop management decisions. The in class’ technical support. Many customers pest management decisions based on hard Belgium and the Netherlands, with plans to
A pioneering company with strong beliefs that robotization, artificial computer always wins!” receive a visit from a technical adviser at data.” expand into Continental and Eastern Europe.
intelligence (AI) and digitalization are set to shape the future of greenhouse least every two weeks. While highly labour With OKO, growers can improve the An autonomous model is due in 2022.
growth, Biobest has recently announced two new partnerships with companies Using data analytics to improve IPM intensive, the advent of damaging plant glasshouse climate as well as pest and disease
leading these fields. viruses – such as Pepino Mosaic Virus control using IPM. While benefiting from Pollination robots
Turning to IPM, crop scouting remains a vital component (PepMV) and Tomato Brown Rugose Fruit cost savings, growers spray less frequently
Data-driven growing of biological control strategies. While highly labour intensive, Virus (ToBRFV) – as well as the human so plants are less stressed helping optimize Continuing on the theme of AI and
it is also selective – as it is unviable to monitor every plant. virus COVID-19, means regular visits are not yields. digitalization, in June Biobest announced
“In simple terms agriculture involves drilling seeds in a field, adding inputs - “Our recently launched Crop-Scanner App, which we always ideal or permitted. “With the trend towards larger-scale a new strategic alliance with Arugga AI
such as fertilizer, agrochemicals and irrigation - and then largely leaving mother developed in close collaboration with the Israeli company “Particularly during the last 18 months, growing operations, involving multi-sites, Farming of Israel - which will see it take the
nature to get on with it,” says Karel Bolckmans - COO of Biobest. “In contrast, Agritask, facilitates recording and visualizing scouting data - we have seen a growing need to provide best OKO can help deal with this complexity,” lead in robotic pollination in North America.
growers utilizing high-tech glasshouses have far more control over their plants helping customers make better decisions in their crops,” says possible technical advice in the absence of says Karel. “Major growers can no longer According to Karel Bolckmans, there are
– they can steer crops minute-by-minute, manipulating parameters including Karel. “The next logical step is to improve early detection regular visits. To draw the right conclusions afford to rely on their gut – they need hard certain situations where robotic pollination
temperature, relative humidity, CO2 concentration, light, electroconductivity (EC) of pests and monitor their evolution in the greenhouse using remotely, we need access to powerful and data to do the best job possible.” can work more effectively than bumblebees.
sensing cameras and computer vision technology.” accurate data harvesting, using artificial Karel predicts data-driven IPM and “If the technology is better – you cannot stop
Biobest has entered a new channel partnership with it,” he says. “It will always win and, rather
ecoation – the Canadian developer of automated greenhouse than fight it, it is better to embrace and work
management and crop health monitoring technologies. Biobest with it. In high-tech tomato crops, pollination
is now offering ecoation’s OKO machine - centered around robots can significantly increase yields
closed-loop IPM, yield production assessments and crop work compared to bumblebees.”
quality checks – to growers in Europe. In comparative trials in high-tech tomato
Karel says, “Driven around the greenhouse on the pipe- crops, Arugga’s pollination robots have
rail system, the OKO scouting robot looks at each plant. It boosted pollination levels by 2-5%, compared
is programmed to detect abnormalities by recognizing biotic to bumblebees. This higher fruit yield equates
(biological) and abiotic (environmental) plant stresses. to significantly higher returns per hectare.
“OKO can detect abnormalities invisible to the naked eye In many parts of the world, high-tech
and uses this data to create ‘heat maps’ of the greenhouse. greenhouses are turning to artificial light and
Accurately pinpointing areas where a plant, or group of plants, shade screens to optimize growing conditions.
is showing sign of stress and underperforming – it also records However, this can negatively impact
the cause. bumblebees causing orientation problems.

regev hybrid fungicide
wins the fight against

“The bumblebees can find it difficult to No-touch pollination glasshouses technologies, as well as in crops
early blight
navigate back to their hives,” explains Karel; such as blueberries, melons and strawberries -
“This is a particular issue in speciality tomato Travelling between rows, the Arugga which are not reliant on buzz pollination.
crops - which require two to three times as Pollination Robot’s cameras recognize each “At Biobest we set out to provide growers
many bees compared to standard types.” tomato flower cluster and points an air gun at with the very best solutions. Before Biobest
During extremely hot periods, the it, shooting a calibrated pulsating air current pioneered the commercial production of
pollination robot comes into its own. “In - vibrating the flowers and loosening the bumblebee hives, growers of protected crops
high temperatures, flower and pollen quality pollen. were largely reliant on manual pollination.
can decrease and require significantly more “The robot mimics the buzz pollination Highly labour intensive, they had to vibrate
vigorous shaking to loosen the pollen,” of bees but, importantly, does not touch the plant clusters individually using hand-held
explains Karel. plant,” says Karel. “Plant viruses - such as devices, tap crop wires or resort to spraying
“We are setting up major trials with four PepMV and ToBRFV - can be mechanically synthetic plant hormones to stimulate fruit
leading North American tomato growers and transmitted within a crop so ‘no contact set.
are confident the results will be good. There pollination’ is ideal. Indeed, the robot is “Biobest bumblebees revolutionized
is no doubt, pollination robots have a bright coated with a special disinfectant paint. pollination back in the 1990s. Thirty years
future in high-tech tomato crops. “Looking to the future - while the robot is on and we are still as enamoured with our
“From a practical standpoint, the robot moving around the crop it has the potential to bees! While bumblebees are set to continue
needs a parallel pipe-rail system to run along carry out other functions, to multitask.” to play a vital role pollinating many high-
and, of course, the economics must add up. value crops, we are thrilled to be part of the
There are plenty of low-tech greenhouse Future for bumblebees next revolution in tomato pollination using
tomato crops in the Mediterranean and robots.”
elsewhere where bumblebees will continue to As to the future of bumblebees, Karel
play a vital role in pollination and ultimately says they will still play the key pollination
yield.” role in countries reliant on less sophisticated Source: Biobest
Thanks to all your support we have won the Julie Pasche | Inkster, ND | 2020 | 10 Applications
Program 1 = Stargus 2qt (1-3); Echo Zn 34oz (4,6,8,10); Manzate Pro-Stick 2lb (5,7,9)
Program 2 = Echo ZN 34oz (1,3,4,6,8-10); Quadris 9oz + Manzate Pro-Stick 2lb (2); Luna Tranquility 11.2oz + Manzate Pro-Stick 2lb (5); Scala 7oz + Manzate Pro-Stick 2lb (7)
2020 Spanish National Innovation Award
Recent trial results demonstrate REGEV® hybrid fungicide delivers remarkable
control of Early Blight in potatoes. And that’s just one example of its efficacy.
REGEV is the first fungicide to unite the disease control power of botanical
and conventional chemistries. This truly innovative combination provides
growers multiple modes of action to control devastating diseases in potatoes,
fruits, vegetables and soybeans, while enhancing plant growth and yield.
To learn more and find your local distributor see STK-AG.COM
National
Innovation Award
2020
Anuncio_SEIPASA_PNI2020_Agropages_jun2021.indd 1 28/5/21 9:22 2021 Biologicals Special 73

Always read and follow label directions. REGEV fungicide may not be registered for sale or use in all places. Please check with your local extension service or other authority to ensure
registration status. REGEV is a registered trademark of Stockton (Israel) Ltd. All other trademarks are the properties of their respective companies. ©2021 Summit Agro USA LLC.
an effective and unique tool for resistance Registration reduced chemical load on the environment
management which is suitable for Integrated compared to other mixtures based on two
Regev™ – A Broad-Spectrum Hybrid Pest Management (IPM) programs. This

combination results in a reduced synthetic
chemical load on the environment compared
Regev is already registered in Israel,
Philippines, Serbia, United States and various
Latin American countries for various crops
traditional chemicals, leading to reduced
residues in food.
The preventive and curative activity of
Fungicide for Disease Control to other mixtures based on two traditional

chemicals.
and diseases. It is currently in the process of
registration in Brazil, Mexico and the EU.
Regev, related to its efficiency of contact,
mesosystemic plus systemic activity by a
single application, together with the indirect
Field trials Summary activity via the host plant by systemic
resistance, leaving little residue and providing
Regev is currently used for controlling The different modes of action of TTO and significant added value to growers, make
Introduction of action against broad-spectrum of plant pathogens a broad range of diseases on arable crops, difenoconazole, created by a combination of Regev an important component in plant
and improved efficacy. The suggested hybrid cereals, fruits crops and vegetables. Diseases a natural product (TTO) with broad-spectrum disease control. Regev has an expanded
The global search for plant-protection solution can be the ‘bridge’ between conventional effectively controlled by Regev include activity, make Regev an effective and unique spectrum over either component alone and
solutions that are both environmentally safe and agrochemical farming and sustainable farming. powdery mildews, apple scab (Venturia tool for resistance management. It presents has demonstrated activity on a wide range
effectiveness is driven by the need to supply That’s because it is a ‘pre-mix’, so it is easy-to- inaequalis ), Black Sigatoka (Mycosphaerella multiple modes of action (FRAC Groups F7 of plant diseases. It can therefore be an
food to the ever-growing world population. The use, in the exact same way as the grower’s current fijiensis ) in banana, species of Alternaria , and G1) to help prevent the development effective and easy-to-use ‘bridge’ solution for
call for chemical load reduction is an important chemical pesticide. To the best of our knowledge, Cercospora , Botrytis , Rhizoctonia , of resistance. This combination results in a controlling various diseases.
Dr. Moshe Reuveni aspect for sustainable agriculture. Recently, this is the first bio and chemical-based hybrid Pyricularia , Helminthosporium , Sclerotium
Chief Scientist of STK documented issues of widespread environmental product in the industry. and more. Numerous trials have been
bio-ag technologies, Israel contamination, toxicity to non-target organisms conducted with various crops in different
and negative effects on human health by synthetic Modes of action countries. Here we present an example
agrochemicals have led to a resurgence of interest of Regev activity against black Sigatoka
in ‘natural’ means of pest and pathogen control, The fungicidal and antimicrobial activities of (Mycosphaerella fijiensis ) in banana.
including intensified searches for new sources of TTO against fungal pathogens, as documented in In a field trials in Colombia, efficacy
biopesticides and botanical pesticides. The latest the literature, are derived from its ability to inhibit of Regev applied alone was compared
solutions are generally used in crop protection and respiration and disrupt the permeability barrier to systemic fungicides, each applied in
contain secondary metabolites, which can be (but presented by the membrane structures of living tank mixture with a protectant fungicide
not always) involved in plant defense mechanisms. organisms. Our recents studies showed that TTO mancozeb. Untreated banana plants served
Among the latest solutions, the essential oils are had a moderate effect against spore germination as controls. Four foliar sprays of each
considered to be attractive for plant protection. and significantly inhibited lesion development and fungicide/mixture were applied at spray Figure 1. Efficacy of Regev (TT+Difenoconazole) applied alone and systemic fungicides each plus
Tea tree oil (TTO) is a valuable essential sporulation of fungal pathogen. TTO was found volume of 19 L /ha at 10 days intervals. mancozeb in controlling of black Sigatoka in banana plantation. Star on bar indicates significant
oil extracted by steam distillation of Melaleuca to disrupt the fungal cell membrane and cell wall The results given in Figs. 1 and 2 show difference (P < 0.05).
alternifolia (belonging to family Myrtaceae) in plant tissue infected with pathogenic fungi, that systemic fungicides tank mixed with
leaves. It contains many components of terpenes, which explains why it exhibited strong curative mancozeb reduced disease severity as
sesquiterpenes, and their respective alcohol. The activity against fungal pathogens, making it a expressed by percentage of infected leaf
oil has been shown to be an effective antiseptic, unique product and enabling growers to use it even area compare to untreated control plants.
antifungal and bactericide. In the recent decade when the disease is already visible on the tissue. In However, Regev (TTO+difenoconazole) was
it was found to be effective against a broad addition, TTO was found to be an activator of plant significantly more effective in controlling
range of plant-pathogenic fungi in numerous itself defense mechanisms and systemically induced black Sigatoka.
crops, including vegetables, herbs, coffee, rice, resistance in plants. Resistance management. Regev has
grapevines, bananas, and fruit trees. (I would use photomicroscopy of disease cell a unique multiple functional activity and
New effective alternatives that can provide being ruptured here, which I have and will include.) presents a lower probability for resistance
different and multiple modes of action with a The sterol biosynthesis inhibitors, including development or cross-resistance in plant
lower risk for fungicide resistance, and which difenoconazole, affect the fungal cell membrane pathogens, so it could be an important tool in
place a smaller chemical load on the environment by inhibiting C-14 demethylation of lanosterol or preventing development of cross-resistance
concomitantly with consistent disease control, are 24-methylenedihydrolanosterol, a biosynthesis during the season. Its application can be
required to increase options for the control of plant step that occurs during conversion of lanosterol to rotated with products that exhibit differing
diseases. The newly developed fungicide Regev™ ergosterol, the final product of fungal cell membrane modes of action and to which populations
EC (STK Bio-Ag Technologies, Petah Tikva, sterol synthesis. of fungal pathogens have shown a loss of
Israel), a hybrid formulation containing 200 g/L The different modes of action of TTO and sensitivity, so that population of pathogens
of the systemic triazole fungicide difenoconazole difenoconazole, i.e. a combination of a natural less sensitive to chemical products can be
reduced. Figure 2. Efficacy of Regev (TT+Difenoconazole) applied alone and systemic fungicides each plus
plus 400 g/L of TTO, is a unique prepacked product with broad-spectrum activity (TTO) and
mancozeb in controlling of black Sigatoka in banana plantation.
formulation which provides various mechanisms a traditional site-specific chemical, makes Regev

Viewpoints Viewpoints
Biologicals Business Development at Bayer, UPL, Bayer Syngenta

Syngenta and Sumitomo Chemical Benoit Hartmann, R&D, Head of Biologics at Bayer Corey Huck, Global Head Biologicals at Syngenta
AgroPages interviewed the leaders at the multinational companies. They talked about
their biologicals business growth and shared their views on the industry development. Strategic position of biocontrol business Syngenta Biologicals
As a global agriculture leader committed to introducing solutions that help Syngenta Biologicals bring our science-based innovation to offer more
farmers become more profitable and sustainable, we recognize that biologicals choices and flexibility for growers. Today’s farmers need more sustainable
UPL Sumitomo Chemical

will continue to play a central, and growing, role in the overall Bayer Crop
Science strategy and product portfolio. We aspire to lead and shape the
ways of growing their crops, that respond to consumers’ demands about the
food we eat.
development and growth of this high-potential market. In 2020, Syngenta Crop Protection acquires Valagro, an innovation
Fabio Torretta, Global Head of Sustainable Biologicals likewise will be a game-changer in our efforts to pursue more pioneer in the field of biostimulants. The investment positions Syngenta
Solutions at UPL Ltd. Regina Rieckenberg, Vice President, Global Marketing
and Business Management at Valent BioSciences sustainable agriculture. We have made bold commitments to reduce both as one of the key global companies poised to shape the rapidly growing
the environmental impact of crop protection and volume of greenhouse gas Biologicals market.
emissions produced by agriculture by 30 percent by 2030. Having the most As for innovative products, TAEGRO® is a biofungicide that we are
Biologicals in different market regions Valent BioSciences’ business focus advanced biological and synthetic crop protection will help make these targets commercialising through a collaboration with Novozymes and recently
It has been clear for several years that the green agriculture movement is Valent BioSciences LLC (VBC) has been a wholly owned subsidiary of achievable. launched in the EU, which can be used as part of integrated disease
primarily being led by Europe, both in their appetite for biological treatments Tokyo’s Sumitomo Chemical Co., Ltd. since it was acquired in 2000. We are a I'd also like to clarify that our goal is not to separate biologicals from other management programs. Another innovation is ISABION®, a top-selling
and in their agenda setting role as a major food import market. From the leader in the biorational marketspace, with our five business units: Biorational crop protection practices, but instead demonstrate how they can complement amino acid-based biostimulant, especially developed to help cash crops like
European Green Deal to the Farm to Fork strategy, the trading block is setting Crop Enhancement, Biorational Crop Protection, Biorational Rhizosphere each other for optimal benefit within conventional farming systems. fruits, vegetables, and specialty crops to overcome stresses like transplanting
the agenda for regional agricultural practices and the standards demanded from (Soil Health), Public Health and Forest Health. We intend to continue shock and cold stress. Valagro’s Talete is a new solution for sustainable water
imports from the USA, Africa and the Middle East. The complex regulatory leading the market in these sectors through the power of fermentation and
Achievements from cooperation management working directly on plant physiology to help farmers to manage
environment and long line for registrations will unfortunately limit the growth microorganisms. In the past few years, we acquired Mycorrhizal Applications Bayer Crop Science operates under the premise of open innovation, water use more efficiently.
of BioControl products in EU in the coming years. LLC, the world’s leading supplier of mycorrhizal soil inoculant products, maintaining a collaborative spirit and open mind to identify partnerships that
In Latin America, UPL has a leading position of BioSolutions in multiple along with Pace International LLC, which provides sustainable postharvest can bring imaginative agriculture possibilities to life. This is no different across Business development
countries including Brazil, Mexico, Guatemala, Colombia and Chile. Appetite solutions and technologies, equipment and technical services. our biologicals work. In step with the increasing demand for Biologicals globally, we have a
here is growing, and we see great potential for our BioSolutions line to grow We are confident that we will continue to be the partner of choice in growing footprint in Biologicals in Asia, evident that Asia is an important
exponentially in the next ten years with launch and penetration of several Development of biorational business biological innovation for a variety of reasons, including our development market for Syngenta and Valagro. For example, our bestselling biostimulant
products like Biozyme®, Biotron plus®, Vacciplant and K-fol®. Sumitomo Chemical foresaw the tremendous potential of the biorational capabilities and digital know-how, our global footprint, our ability to integrate ISABION® is being launched in South East Asian countries like Thailand
We plan on strengthening our presence in the Chinese market, and business when it acquired Valent BioSciences more than 20 years ago. solutions in crop systems from planting to harvest, our commitment to to improve the quality of tropical crops like durian. In China, Syngenta has
increasing access to, and adoption of, biological alternatives to traditional Our business fits well with Sumitomo Chemical’s focus on innovation and sustainability and our vast biological product development experience. Building formed a strategic partnership with a technology start-up company Sound
crop protection products. In China, UPL has already introduced seaweed developing products that create and deliver value, as well as a dedication on our recent successes in developing products with external innovation Agriculture to explore opportunities to improve nitrogen use efficiency,
based BioStimulant portfolios in the 3H crop region- one of the nine principal to corporate social value and fostering a more sustainable future. We are leaders such as Novozymes (BioRise) and Alpha Biocontrol (FLiPPER and reducing dependance on synthetic fertilizers, while maintaining on-
agricultural zones in China - and is ready to put forward a series of high confident about the future of biorationals and intend to continue growing and Missito), we see major opportunities to expand our partnership base and farm productivity. The technology stimulates microbes in the soil and has
efficiency BioControl products in the immediate future. innovating in order to deliver effective solutions to growers around the world. portfolio of innovative and sustainable solutions by increasing our access to the sustainability benefits. Our intention is to be the collaborator of choice for
vibrant external innovation community focused on the discovery of biological industry leading innovators and to build a science-based leading Biological
Large-scale acquisitions started Global soil health initiative candidates. portfolio globally, in China and beyond.
Growth in zero residue production and organics directly leads to an Our purchase of the Mycorrhizal Applications business has already paid We're already seeing the benefits of our open innovation approach coming We are open to growth through both acquisition and partnerships that will
increase of consumption of biologicals and the need for precision agriculture. great dividends, and we expect it to continue sparking development of new to life. For example, we recently launched our Vynyty Citrus device, a first- drive Syngenta’s ambition to be the global leader in biological plant and soil
We expect the entire spectrum of application from seed treatment and soil soil health technologies and products. In addition, we recently established a of-its-kind container with biological pest control liquid formulated with health technologies. We continuously explore opportunities to enhance our
health to post harvest will be covered with multiple biological options in the more formal relationship with the Biorational Research Unit at Sumitomo pheromones and natural pyrethrin to control citrus pests without generating position in the biologicals market.
coming years, with the larger trends of consolidation, collaboration, and joint Chemical’s Health & Crop Sciences Research Laboratory in Japan. One harmful residues. At an industry level, the trend of acquisition as a growth mechanism is
ventures continuing as well. of the key areas of focus will be on various projects related to arbuscular not surprising given the potential of the biologicals market and the benefits
We are dedicated to breaking new ground in agricultural innovation and mycorrhizal fungi (AMF). Valent BioSciences is continuing to work with a
Biopesticide efficacy that come from being a larger player. We estimate that the Biologicals market
increasing collaboration between players across the food system in order to variety of leading organizations to educate the industry about the importance A significant part of our biologicals program is understanding where we will grow to more than USD10 bn by 2030, more than double what it is today.
meet the ever-growing challenges facing the sector. In the last 50 years, we of soil health through partnerships and other high-profile initiatives. can deliver the greatest value. Doing so requires close collaboration with
have grown both organically and through carefully considered acquisitions, customers to identify both where they may be struggling with biologicals or Next breakthrough innovation
the most significant of which has been the acquisition of Arysta LifeScience in Vision of the future development potential sources of hesitation to adopt them. We're pursuing new formulations Looking further into the future, there are technologies at a genomic level
2019, bringing to UPL a strong and complementary portfolio of BioSolutions. Biorationals, sustainability and carbon neutrality are key elements of to make our biologicals offerings more durable and beneficial. In particular, that we are harnessing to create sustainable solutions. We use such technology
This was more than an opportunity for growth, but a statement of intent for Sumitomo’s strategic planning for growth in the Health and Crop Sciences we're concentrating on bacteria-based products rooted in spore stability for to characterize our microbial and plant extract products and also understand
our belief in the role of a major agribusiness now and in the future. Far beyond Sector. Valent BioSciences is renowned for its innovation, best-in-class easier handling. their metabolic pathways and physiology to develop safe and biologically
emerging as a top 5 agricultural solutions company worldwide, the merger manufacturing and broad biorational product portfolio that complements We also recognize that no one product type can answer the entire industry's active, sustainable products.
drove a new purpose for UPL, based around collaboration. Sumitomo Chemical’s conventional products. Some of the key long-term needs. That's why we're prioritizing the acceleration of access to all potential A particularly exciting area of research is RNAi, where a biocontrol
One recent example is the partnership with Novozymes in February growth drivers for our business growth include the billions of additional platforms. For instance, we are integrating plant extracts and pheromones to harnesses a natural cell process RNAi as a new mode of action for biological
2021, aiming to offer a complete range of BioSolutions and crop protection people on earth who will need more food; climate change; greater awareness complement our more traditional microbial-based solutions. Additionally, we've pest control. The RNA molecule is ubiquitous, natural and biodegradable.
products to the Argentinian market. This partnership will provide greater of soil health; loss of conventional crop protection products; non-fertilizer initiated new research to explore how to stabilize non-spore organisms for Syngenta Biologicals is very excited to be shaping the market in these new
access to technology for farmers and will help them achieve improved yields yield improvements; and increasing consumer demand for safe, local and extended shelf life. While we don't have every answer just yet, we see plenty areas and helping growers meet challenges in sustainability and the way our
in a sustainable manner. Collaboration has played an indispensable role in high-quality food. We are on a mission to reimagine agriculture and public of opportunity for new products in these areas and are excited to pursue them foods are produced.
developing our portfolio, and the OpenAg model will continue to guide our health through the power of fermentation and microbiology. further.
future projects and products.

development as well as the launch of the new compound fertilizer brand - NovaTec®
with remarkable results being achieved; NEW YONFER has cooperated with biological
Haifa, Nutrien, Kingenta and New companies including Qinhuangdao Leading Bio-Agri, Fujian Mata, Sugon, Nanjing
Shineking and US Biowish in biostimulant and functional product development and
promotions, having built up NEW YONFER’s BAIBENGBANG prime single product
Yonfer Fertilizer’s Views on the brand fertilizer product.

In 2018, NEW YONFER and China Agricultural University jointly launched a crop-
specific fertilizer lab as approved by the Chinese Ministry of Agriculture and Rural
Biostimulant Industry and Market

Affairs. Through the operation of the lab, product technology and agronomic technology
are further integrated, which has facilitated the development of a special fertilizer
product series that enable higher nutrient utilization, high yield and quality upgrading
as well as soil improvement, providing guidance to the fertilizer industry to extend from
the standalone market orientation towards technology-driven integrated development.
This provides a technical backup for the upgrading of the fertilizer industry and the
sustainable development of agriculture.
In the years ahead, NEW YONFER will continue to increase its independent R&D Jidong Zhai
Comparing the global crop protection market (approximately US$60 billion), with the crop seeds and biological technology (US$45
efforts, adhere to the green development idea, targets at the international level, boost Vice president at KINGENTA
billion), fertilizers (US$156 billion) take the largest percentage in the whole agri-inputs market.
product innovation at a high level and strive to construct a scientific and technological
However, keeping the environmental impact in mind, it has been asked to reduce the carbon footprint during fertilizer production and
sustaining platform as well as a disruptive innovation platform as driven by the
increase the efficiency of the application. This has resulted in the increasing traditional fertilizer companies invent biological technology
market, with international vision, such that the company can build up its sustainable
and digital tools in the non-traditional territory. The rapidly increasing market of biostimulants, with fertilizer giants getting involved in this
competitiveness in a higher dimension. released one after another to the market in recent years,
sector, is witness to that. AgroPages interviewed four fertilizer companies for their attitudes and strategic layout on biostimulants, they are:
The opportunities to the company in the process of research and promotion of novel with great success.
- Casey McDaniel, Managing Director at Loveland Products & Actagro (subsidiary of NUTRIEN)
fertilizers will be from 1) the acceptance of novel fertilizers in the Chinese agrochemical KINGENTA has built a large-scale production
- Natan Feldman, VP Marketing, Business Development & Innovation at HAIFA GROUP
market has reached a high level, which gives manufacturers the benefit of fewer inputs line, which mainly produces mineral humic acid and
- Jidong Zhai, Vice president at KINGENTA
on market education; 2) the state’s supervision and regulation of the fertilizer market microparticle fulvic acids. The company’s series of
- Yanfeng Wang, Vice president at NEW YONFER
are constantly improving, which is conducive to standardized and well-regulated biostimulants such as high active alginic acids and
market development and healthy competition among enterprises; 3) the gap between chitosan oligosaccharides extracted from imported high-
Chinese industry and the world is further narrowed in respect of novel fertilizer original quality seaweed and shrimp shell is widely accepted and
innovation, technology and talent pool development, which may enable Chinese industry welcomed by the market. In terms of product promotion
to possibly surpass the world’s industry level in some fields. This will be of help to and application, KINGENTA has fully utilized its
Could you introduce your product line and the plan? The Chinese manufacturer’s independent innovation, improvement of innovation efficiency advantages of professional production and promotion
opportunities and challenges in popularizing biostimulant products? and quality, as well as the introduction of professional talents. team to promote and produce widely-used water-
The main challenges are 1) the homogenization of novel fertilizers currently on the soluble fertilizer, liquid fertilizer and foliar fertilizer in
NEW YONFER: As an industry leader, NEW YONFER started product current market is quite serious, it is still difficult to achieve a substantial breakthrough in combination with each other, using biostimulants as raw
innovation 10 years ago, that was the time when we began cooperating with Zhang the short run, which requires time and investment; 2) how to resolve the conflict between materials. Biostimulants are also used as raw material
Fusuo, a Chinese academician from the China Agricultural University and experts the major single novel fertilizer and the individualized novel fertilizer is a test of a to upgrade ordinary granular NPK compound fertilizers,
from the national nutrient management network. We have jointly set up the Novel manufacturer’s capability, management and wisdom. which has been quite successful on the market. As
Fertilizer Research Center specializing in the research and development of novel As regards biostimulants in the Chinese market, the widespread application of this a novel fertilizer, biostimulants are well-recognized
fertilizers such as soil-targeted and crop-oriented special fertilizers. Till now, NEW kind of single product may not be very promising in the short term. More importantly, and accepted by the majority of farmers, for whom a
YONFER’s crop-oriented special fertilizers account for 75% or above, which is far biostimulants have been considered a synergistic factor to be integrated with mainstream professional technical service is required, which has
higher than the average industry level. This has played a solid foundation backing up products for promotion and application. In the eyes of large enterprises, the benefit proved to be a challenge to biostimulant manufacturers.
NEW YONFER’s industry-leading position in crop-oriented special fertilizers, to lead is that biostimulants can be used as both a synergist for integration with mainstream At the same time, biostimulants improve the quality of
the way for the compound fertilizer to shift from general use to special use. products and be used as a single product, or even a complimentary item. This will play a agricultural products, enhance the nutrient utilization
In the past five years (China’s 13th Five-Year Plan period), NEW YONFER has role in flexible uses and promotions of quick product releases via proper sales channel. of macro-element fertilizer and improve the soil
continually increased its R&D inputs, accelerated the process of product innovation, condition to contribute to the government’s requirement
upgraded novel fertilizer innovation facilities, being the first to complete the novel KINGENTA: Over the last 20 years, relying on the advantage of the national-level of “reduction of fertilizer and increase of efficiency.”
fertilizer variety expansion and function increase. The product portfolio of novel fertilizer R&D center within our company, KINGENTA has spent a lot of manpower, Biostimulants are expected to play a more important
fertilizers has been systematically optimized and upgraded to meet the market demand material and financial resource on research and development of novel products. Efforts role, which will provide great market opportunities in
for product diversity, which further increases the proportion of novel fertilizer have been made on research programs covering nitrogen emission reduction, phosphorus the future.
applications. efficiency enhancement, integration of pesticide and fertilizer, soil improvement and
Since 2017, NEW YONFER has cooperated with COMPO EXPERT in a Yanfeng Wang product quality upgrade, resulting in several outstanding R&D achievements, such HAIFA: As an international company that stands
comprehensive and in-depth manner covering technology transfer, localized Vice president at NEW YONFER as humic acid, seaweed extracts and chitosan oligosaccharide, which are part of the at the forefront of the plant nutrition industry and
manufacturing and brand integration in the fields of high-quality compound fertilizer company’s key research results. The products under these research programs have been committed to the success of farmers worldwide, we

recommendations for particular cases. Haifa's thorough knowledge and experienced division,” which has led to more and more serious homogenization of development
teams worldwide provide excellent basis to develop comprehensive guidelines for the of the novel fertilizer. In this case, low-level competition is inevitable. I believe
application of our biostimulants. that enterprises all over the world are concerned and are looking forward to the
A great opportunity for our biostimulant products lays in the great synergism emergence of revolutionary technological breakthroughs. Whosoever can make
between biostimulants and mineral fertilizers: while the fertilizers provide the nutrition available such technology will win over the competition in the future.
that intensive crop production requires, the biostimulants allow the crop to reach its
growth potential with better uptake. The combination of Haifa's plant nutrients and KINGENTA: KINGENTA’s global market consists of two parts: one is the
HaifaStim™ (or Haifa Poly-Feed™ Stim products) creates fully integrated plant acquired market through capital investment while the other is the market expansion
nutrition that meets the constantly rising needs of modern agriculture. through the establishment of our affiliates. Over the past 10 years, KINGENTA
has expanded its international market through investment and the establishment
NUTRIEN: Nutrien is the world's largest provider of crop inputs and services, of affiliates, having promoted products to cover six continents across more than
playing a critical role in helping growers sustainably increase food production. Our 80 countries. KINGENTA’s two largest overseas regional markets are Southeast
retail operations, Nutrien Ag Solutions, serve growers in seven countries across three Asia and Europe, where water-soluble fertilizers are dominant products, whilst
continents, with a history that goes back almost 50 years. Our size and scale, combined biostimulant promotion is just the beginning. Compared with the overseas market,
with our commitment to innovation and technology, allow us to provide growers with the fertilizer market in China is relatively more active with more fierce competition,
the best products, advice and solutions to maximize yields and improve their bottom and people are more open to novel products. Therefore, there is a bigger opportunity
Natan Feldman line. We see a very clear difference between fertilizer and biostimulants, but also and market space in China for novel fertilizer products such as biostimulants.
VP Marketing, Business Development & recognize they can be mutually beneficial when applied together. Through Loveland
Innovation at HAIFA GROUP Products, a proprietary product line of Nutrien Ag Solutions, the company has taken a HAIFA: Haifa Group is a leading global supplier of specialty plant nutrients Casey McDaniel
leadership position in the biostimulant space and continues to innovate our portfolio. for advanced agriculture. We have 16 subsidiaries worldwide, that operates in more Managing Director at Loveland
than 100 countries across five continents. To expand into new markets, Haifa opened Products & Actagro
Could you introduce your global markets? In your biggest market is three subsidiaries in the last years, in China, Turkey, and Colombia.
study and develop innovative solutions continuously. there any market difference between fertilizers and biostimulants? In Southern Europe (Spain, France, Italy, Balkan countries, and Greece) Haifa
Global climate change creates a lot of extreme situations distributes biostimulant-based products since the mid-1980s. This acquainted us
which we have not witnessed in the past and poses new NEW YONFER: The major market of NEW YONFER is China and South East with various biostimulant solutions, along with application experience. Thanks to and more serious. In the past, when crops grew in a better
challenges to growers. We have introduced HaifaStim™, Asia. Biostimulants in China is in the scope of the Novel Fertilizer. Novel fertilizer is a initiatives of local teams, Haifa Group has gathered experience with biostimulants in environment, what was needed was just to provide nutrients.
our line of biostimulants, with the understanding that broad, extensive and dynamic concept. Each individual has a different understanding of south Europe. We now take advantage of this experience, including promotion and However, under the stress, the absorption, utilization and
these nutritional supplements can help growers to it, being positioned differently by different people. There are differences in its market regulatory issues. Some 120 front warehouses worldwide allow us to ensure product metabolism of nutrients would encounter problems, which
produce successful yield under stress situations. Along characteristics. In general, the characteristics of the Chinese novel fertilizer market may availability and support logistical needs when expanding our activity to other parts had to be effectively controlled and regulated, for which
with our nutritional products, efficient application be summarized as follows: of the world. there were long-term and systematic solutions, as well as
methods, knowledge, and technology, HaifaStim™ 1.High-growing, with great potential. The Chinese novel fertilizer market has Now, with the launching of HaifaStim™, biostimulants have become an integral short-term measures. Biostimulants are one of the practical
products complete whole 360° plant nutrition solutions sustained double-digit high-speed growth in the past ten years, which I believe part of our portfolio and are available in all our markets. and effective solutions that farmers can feel in person. It
for our customers. will not go down in the next ten years but will continue with better performance, is relatively easy to materialize the control measure with
In the first stage, we launched seven premium attributable to the huge potential of China's economic development, as driven by the NUTRIEN: NUTRIEN is the world's largest provider of crop inputs and biostimulants for them to affect crops, resulting in the rapid
products that combat various stresses, as implied by their strong promotion and support by the government’s initiatives of rural revitalization, services, playing a critical role in helping growers sustainably increase food development of the product on the market. Finally, I hold
names. For instance, HaifaStim™ VIGOR facilitates agricultural modernization, green and sustainable development of agriculture, as well production. Our retail operations, Nutrien Ag Solutions, serve growers in seven the view that biostimulants are still a niche market, which
nutrient uptake and assimilation; HaifaStim™ FORCE as the advantage and competitiveness of the Chinese manufacturing industry. In a word, countries across three continents, with a history that goes back nearly 50 years. Our will not replace nutrients. Its fundamental function is to help
balances energy storage and transfer in the plant, and not only in the past but today, also for a long time to come, I believe that the Chinese size and scale, combined with our commitment to innovation and technology, allow us to better understand farming from the perspective of life
so on. The HaifaStim™ range also includes the Haifa novel fertilizer market will be undoubtedly one of the world’s best and fastest-growing us to provide growers with the best products, advice and solutions to maximize science, and hence to establish a more scientific and rational
Poly-Feed™ Stim range of our well known soluble NPK markets with the greatest potential. yields and improve their bottom line. We see a very clear difference between product concept.
fertilizers- Poly-Feed enriched with biostimulants. Haifa's 2.Fierce competition and chaotic market: The competitiveness and profitability of fertilizer and biostimulants, but also recognize they can be mutually beneficial when
biostimulant products improve various aspects of plant novel fertilizers are much higher than conventional products. Motivated by profitability, applied together. Through Loveland Products, a proprietary product line of Nutrien KINGENTA: The biostimulant market is a blue
development and the growth environment, thus enabling the market competition is going to be extremely fierce, where various means of Ag Solutions, the company has taken a leadership position in the biostimulant space pecan compared with the conventional fertilizer market.
farmers to grow crops more efficiently. e.g, HaifaStim™ competition will emerge endlessly, which will lead to vicious competition like an and continues to innovate our portfolio. The presence of global fertilizer and pesticide giants in the
Vigor is designed to enhance nutrient uptake and use occurrence of a price war. Due to the specialty and particularity of the novel fertilizer, blue ocean one after another is a good try and a choice of
efficiency. it is difficult for governments to very effectively supervise and regulate the market, thus As a fertilizer giant, what are your attitudes towards chemical the times for the conventional fertilizer industry to switch
Just like any agricultural input, the action of the the situation of market chaos will persist. fertilizer and chemical pesticide multinationals joining the to novel fertilizers, which is transforming and upgrading.
products requires optimal usage – proper choice of 3.Serious homogenization and difficulty in technical breakthrough: In the past 50 biostimulant industry? A biostimulant and conventional fertilizer supplement
product, and correct application of the precise dose at years, there have been no revolutionary technical breakthroughs in China or even in each other, and not exclude each other. It is the same
precise timing. Upon the introduction of the new range the world. The logic of enterprises has been to sell nutrients, sell technologies and now NEW YONFER: First of all, we consider this is an inevitable happening market closely linked together, not two markets that are
Haifa has developed general usage guidelines, and the to sell functions, where the level of market operation and marketing ability need to be in the development of the industry, business competition and product innovation, separated from each other. Biostimulant can be used for
main challenge now is to study specific cases in order to improved. In essence, what is done is more like a sort of function integration, or doing which is normal. Secondly, why is biostimulant attractive? The main reason is that direct marketing development, and more importantly, can
fine-tune the instructions and to come up with customized a simple mathematical calculation such as “addition, subtraction, multiplication and the negative effect of environmental stress on crop production is becoming more be combined with conventional fertilizers to improve the

nutrient efficiency of conventional fertilizers, thus helping to

achieve upgrading of conventional fertilizers.
KINGENTA: In the past five years, affected by the global economy,
national policies and the fertilizer industry development, KINGENTA’s
Russian Biostimulant Industry
Watch: From Research, Field
overseas merger and acquisition process, as well as business expansion,
HAIFA: Biostimulants comprise a relatively new area of have stabilized. Summing up the experience in a cross-border merger and
activity for Haifa, which is anticipated to grow faster than our acquisition as well as international market development, we believe that
general activity. economic globalization is a major trend of world economic development,
The penetration of large, well established companies such
as Haifa in the biostimulants market is very important, and we
anticipate that it will take the market a huge step forward. With
where international competition may take place in the domestic market while
domestic competition may become international. This will become a normal
state. It will be a strategic choice of enterprises to consolidate international
Practice Points of View
our knowledge, experience, R&D, and not of least importance, resources to strengthen corporate competitiveness and endeavor to expand the
logistical capabilities and economic stability, only the large plant international market. Optimization of worldwide business operations makes
nutrition companies can turn biostimulants from niche products two important achievements: (1) dual-circulation of domestic and international
into an essential component of the 21st-century farming practices. markets backed up by the two markets; (2) synergy effect from the integration
of international technology and product development in association with the
The first discussion of the “biogenic stimulant”
NUTRIEN: Nutrien Ag Solutions believes any technology strong domestic manufacturing capacity and agile management; (3) global
theory can be first attributed in 1933 to Prof. V.P.
that provides benefits to both grower customers and the resource sharing, which increases the efficiency of resource utilization and
Filatov, who proposed that biological materials derived from
environment is positive, regardless of who introduces the enhances the competitiveness of enterprises; (4) avoidance of tax and technical
various organisms exposed to stressors, including plants, could
technology. Our commitment to innovation and technology barriers, expansion of development potential to gain a competitive advantage.
affect metabolic and energetic processes in humans, animals and other
through our research and development or partnerships with
plants. To a wide extent, Russia is a region with a vast territory and various
supply partners allows Nutrien Ag Solutions to provide the best HAIFA: In the future, we shall add more products to the HaifaStim™
climate conditions. Therefore, it is rich in mineral and biological resources and can
solutions to maximize yield. Nutrien Ag Solutions has made large line, addressing particular crops and specific situations. Nevertheless, we are
benefit from the acquisition of raw materials and further research on biostimulants. To
investments in this space and will continue to lead with novel seeking joint ventures and willing to invest in new technologies to develop
understand the Russian biostimulants industry from the research and field practice points
BioSolutions. innovative solutions that will help farmers to grow better crops and to face the
of view, AgroPages interviewed representatives of two biostimulants companies,
challenges of climate changes, depleting resources, and others.
LignoHumate and Sibbiopharm.
Will your firm further acquire some companies to Haifa intends to diverse its range of biostimulants, in order to introduce
complete your product line as other companies do in products that will address very specific growth situation, and also products
this industry? with unique activities. These days Haifa's R&D teams are working on the
development of innovative biostimulants, based on special plant extracts,
NEW YONFER: NEW YONFER does not rule out and we anticipate launching in the near future. We also test some other new
involvement in the biostimulant field via acquisition in the future, technologies and shall update our business partners and customers as soon as
but it will not be the only way, because the ways of cooperation Could you please introduce your company?
they will ripe.
should be diversified. We are more concerned about whether a
Kokhan: Lignohumate is a company involved in manufacturing and selling concentrated plant
win-win result can be achieved through cooperation, whether a NUTRIEN: Agrichem, one of our brands acquired in 2018, is
growth stimulators and animal feed additives. Our products’ core feature is the combination of
new source of growth can be created and whether capability can be synonymous with innovation, technology and quality in the field of high
humic and fulvic acids derived from lignosulfonate, a liquid fraction of wood. We have been present
enhanced. concentration liquid fertilizers and the nutritional management of key crop
in the Russian and global markets for more than 25 years, and we are currently cultivating more than
In the past, during our exchange and cooperation with segments in Brazil. Agrichem brings together a complete line of products that
1 million hectares worldwide.
some overseas companies, our experience and feeling are that features high formulation technologies, maximum application security and
Sergey Kokhan Nizhegorodov: Sibbiopharm is a modern Russian biotechnological company involved in the
at present the vast majority of foreign-invested enterprises still superior yield to increase end-to-end agricultural quality and productivity,
R&D Manager of LignoHumate large-scale production of microbiological products, which are used in healthcare, poultry farming,
hold the opinion like the opinion they held in the past regarding thus innovating performance in the following functions: expertise in high
forest and plant protection, crop farming and other areas. In December 2012, Sibbiopharm received
the Chinese market and Chinese enterprises. What they do now concentration formulations; nutrition via seeds; defense induction in plants;
a certificate from the international certification body, TÜV NORD CERT (Germany), according
is still to set up a simple marketing office in China, relying on nutritional diagnostic tool; complementary nitrogen; injection of fertilizers into
to the quality management system, ISO 9001: 2015. Currently, our products are exported to India,
a corporate name, brand and authorization to bring in imported the furrow.
Kenya, Thailand and eight other countries.
products to the Chinese market. This way of doing business to This acquisition and others around the world have allowed us to lead
make earnings is outdated and the business model has gone, as with innovation. Nutrien Ag Solutions has aggressive commitments around
its operation efficiency, cost control, market penetration and Could you briefly introduce the history and current development status of
enabling sustainable acres, achieving emissions reduction, and leveraging
resource consolidation are all ineffective, being not competitive your products?
innovation. Our BioSolutions portfolio will be a very important tool in
on the market. This way of doing business would not be able to achieving these goals.
Kokhan: The history of humic acids, and more precisely, the salts of humic acids, began in the
sustain the business objectives of foreign-invested companies. If
20th century, when it was discovered that natural humus in the soil containing humic substances
adjustments are not made quickly to adapt to the changes of the
Igor Nizhegorodov mixed with water significantly affect the development of plants. After years of research, people have
times and match the Chinese market features, the market share
Agronomist at Sibbiopharm found a way to extract humic substances from raw materials, such as coal or peat, by mixing with
of foreign-invested companies in the Chinese market will be
alkali. Currently, 90% of all humic products in the world are made from coal, as this raw material
worrying. To this end, I suggest foreign-invested companies refer
contains the highest amounts of humic substances compared to other non-renewable raw materials.
to NEW YONFER’s model of cooperation with COMPO EXPERT.
The development status of this category of products is based on mixing humates with other

stimulating components, such as aminoacids representatives of this genus synthesize some the market. Also, the final product contains a opportunities for the use of natural coal and peat, because of its high solubility to protected plants resulting from the use of
and mineral compounds. biologically active substances, including teo-component mixture of humic and fulvic diversity, and the results of fundamental and different humification level. The specifics plant protection agents.
The uses of humates are varied and some phytohormones, such as auxins, thereby, acids, while coal, peat and leonardite humates biotechnological research have relatively of this method are very technical, but it is Biological effectiveness can be expressed
include plant cultivation, animal husbandry, stimulating the growth and development of containing only a humic fraction of fulvic good programmability and potential practical important to note that our product needs to be by various indicators, such as the removal of
decontamination of polluted soils, pharmacy, plants, being a biological stimulator, as well molecules are mostly all washed away from importance. measured differently. the harmful stages of insect development by
biological food additives and cosmetics. The as synthesizing the factors necessary for the raw materials over the time, spanning - Biotechnology offers the possibility Nizhegorodov: The biological and bioinsecticides, a decrease in the number or
latter are popular, because humic acids have a plant growth. Exopolysaccharides promote hundreds of years, during which humic of replacing non-renewable resources with economic efficiency of a product are the main density, a decrease in the spread of diseases
pronounced stimulating effect on every living the mobilization of heavy metals in the substances are formed in nature. Finally, our renewable ones. Therefore, it is considered indicators that decisions are based on, in due to fungicides and seed dressers, and a
cell, not just plant cells. soil, contributing to the self-purification of product is fully soluble unlike other humates, a means of solving the issues associated terms of their competitiveness and feasibility decrease in plant damage due to insecticides,
Nizhegorodov: Sibbiopharm produces a soils contaminated with heavy metals, such which almost always contain ballast particles. with the shortage of non-renewable natural for introduction. These indicators do not fungicides and seed dressers. This indicator
product based on gibberellic acids, Gibbersib, as cadmium, mercury and lead. The first Recently, the manufacturers of natural resources. always correlate with each other. Sometimes, is often expressed as a percentage of the
and the nitrogen fixer, Azofit. representative of the genus, Azotobacter humates began to invest in complicated filter a product that has a lower biological indicators of the control variant in which
Gibberellins are a group of chroococcum, was discovered and described systems to remove ballast. However, such an What is the common standard effectiveness compared to the standard these products were not used or as the
phytohormones of diterpene nature, which in 1901 by the Dutch microbiologist and investment results in a significant and often used in your territory to estimate the can have other positive effects on plants indicators of the reference variant, in which
perform various functions in plants related botanist, Martin Beijerinck. unbearable product price increase. quality or results of a product? and generate higher economic efficiency. well-known and widespread products with
to controlling hypocotyl elongation, seed Nizhegorodov: In general, the Russian Another example is a product that has high similar spectrums of action and compositions
germination and flowering. In the control of What is your view on plant protection product market in 2019 rose Kokhan: The final products of all economic efficiency but is not economically were used.
most morphogenetic processes, gibberellins biostimulants? What are the by 28%, due to an increase in acreage and humates are measured through several profitable due to its high cost. Therefore, Economic efficiency is characterized by
act in the same way as auxins and are advantages gained by local Russian higher agricultural production. The fastest different parameters, which are moisture when conducting demonstration production two indicators, which are the value of the
antagonists of cytokinins and abscisic acid companies developing biostimulants, growing segment of the plant protection content, solid fraction content, ash content, tests, it is necessary to study and consider all additional saved yield or yield increase in t/
(ABA). Gibberellins were discovered by the as well as any challenges? market is the biopesticides sector, in which water solution pH, fulvic and humic acid indicators. ha, as well as the actual economic efficiency,
Japanese scientist, E. Kurosawa (1926), while farmers are showing increasing interest, and content, and content of metals. For measuring Biological effectiveness (BE) is a which is the ratio of the yield in the tested
studying the rice disease, overgrowth, caused Kokhan: Our view regarding almost all large manufacturers offer this the content of humic and fulvic acids, decrease in the intensity of development of or reference variant in relation to the yield
by the fungus, Gibberella fujikuroi Sow, biostimulants is positive if we are talking product in their portfolios. This year, 945.37 Lignohumate uses a different technology harmful biological objects, such as diseases, of the control. Economic efficiency is also
which affects rice crops and causes a specific about them in the context of increasing tons of biopesticides and 5658.32 million from the one used in humates extracted from pests and weeds, or the degree of damage determined by the ratio of the cost of the
disease causing plants to have abnormally plant yields. By using various mechanisms, pieces of entomophages were produced in the
elongated internodes and low seed production. they can work really well in collaboration, Russian Federation.
In 1935, the Japanese scientist, T. Yabuta, and the advantages of Russian producers of Five or six years ago, few people have
isolated gibberellins from this mushroom in biostimulants certainly lies in the amount of heard of biostimulants, but today, this market
crystalline form and gave them their current active trial work done on many biostimulants is one of the fastest growing agricultural
name. in precise proportions to get the best result, sectors, growing 12% to 15% per year. Plant
Another biostimulant produced by such as Lignohumate combined with algae. biostimulants are derived from various natural
Sibbiopharm is Azofit. Nitrogen fixation The main advantages of Lignohumate substances that activate natural biological
plays an important role in the nitrogen cycle compared over other Russian and international processes, enabling crops to cope with stress
in nature, and is the most important source of companies lie in its unique manufacturing and achieve their maximum genetic potential
nitrogen. Members of the genus, Azotobacter, process and the raw material, lignosulfonate, in terms of yield and quality.
play a key role in the soil nitrogen cycle, which no one else uses and results in the At present, biotechnology has rapidly
by fixing molecular nitrogen. Also, highest actives substance concentrations in moved to the forefront of scientific and
technological progress, due to some of its
features, which are:
- Biotechnological production is a
science-intensive production, meaning that its
development entails a significant increase in
economic efficiency.
- In biotechnology, it is difficult to
distinguish between fundamental research,
on the one hand, and applied research, on
the other, highlighted by the fact that in
biotechnology, there is practically no time
gap between obtaining a fundamental result
and developing technologies for practical
development.
- Technologies based on the use of cells
and biological molecules offer considerable

Viewpoints
additional or saved yield while considering

quality, as well as the cost of protective
measures. Its main indicators are net income
indicators will change. Therefore, the final
decision on the feasibility of using this
product in production should be made after
happily a part of. The system allows members
to release a registered agrochemical product
in all EU countries without having to register
Company Directory
and profitability. two to three years of testing at several areas, it in every country. Latin America also has the
The objectivity of a new product such as farms, which differ in terms of Andean Union, which enables members to do
assessment largely depends on the accounting agro-ecological and economic-ecological the same.
correctness of additional costs. Plant conditions. Nizhegorodov: The share of the INDEX：A – Z
protection costs include the cost of the biological method in Russia is no more
ASFERTGLOBAL 88
product, wages, the depreciation of fixed How are the policy attitudes than 3%, as many people, due to lack of
assets, the cost of routine repairs and towards biostimulants? experience in using biological products, use Biolchim 88
maintenance of machines, the cost of fuel conservative methods of protection, such 88
Scientific Consulting Company (SCC)
and lubricants, and the cost of harvesting, Kokhan: The policy attitudes towards as chemicals. Recently, the entire world,
AFEPASA 89
transportation and finalization of the stored humic products are variable in different including in Russia, has increasingly focused A
crop. Wage costs are those paid to tractor regions. However, they are mostly friendly, on the issues related to utilizing microbiology Azotic 89
drivers for spraying crops and transporting as the danger posed by humic products to in agriculture. We managed to significantly Beijing Multigrass Formulation Co., Ltd. 89
B
solutions or water, as well as to workers plants, animals and humans being is graded as expand and deepen our understanding of
Battelle UK 89
involved in preparing the solution, loading level 4, which is the lowest. The only concern the role of microorganisms in plant life
BioBest 90
and unloading the product, along with those in terms of policy is the presence of poor and formulate priority practical tasks to
Certis Biologicals 90
for accounting. The costs of depreciation, quality and ineffective products in the market, reduce the use of nitrogen and phosphorus C
repairs and maintenance are determined along with fake products, but this can happen fertilizers, as well as replace pesticides with Certis Europe 90
for all types of fixed assets involved in the with every type of agrochemical. Regarding microbiological preparations, protect plants
Chengdu Newsun Crop Science Co., Ltd. 90
technological process of plant protection, registration in Russia, it takes two years to from stress created by soil pollution caused 91
such as tractors, agricultural machines and by heavy metals and radionuclides. Every
CITYMAX
register a product and a lot of paperwork must
Compliance Services International (CSI) 91
sprayers. be filed at the Russian Ministry of Agriculture. year, new biological products appear on the
Based on the analysis of the above However, it is often worth it considering how market with practically the same, often unfair DOGAL PESTICIDES AND CHEMICALS INDUSTRY TRADE S.A. 91
D
indicators, a conclusion about the big Russia is, how much land is cultivated and and most importantly illiterate advertising. Evonik Operations GmbH 92
E
effectiveness of using the product and/or how many agricultural holdings are present in Sometimes, they promise to increase yield, 92
F Fertiliser Consultants Network (FCN)
proposals related to its use can be made. the country, specifically in Southern Russia in quality and germination levels while offering
Futureco Bioscience 92
When evaluating plant protection Krasnodar Kray, Stavropol’ Kray and Rostov the possibility of replacing one bottle of
Idai Nature 93
measures in a separate experiment, the results Oblast’. Other countries are also different in organic and mineral fertilizers, as well as not I
are valid for a strictly determined situation, terms of their registration and certification using chemical plant protection products. Ingevity 93
such as the type of soil in a particular field, process, so it is hard to sum it all up. If we The “ecological cleanliness” of a biological
INTERMAG 93
weather conditions, crop variety and number are talking about some special ways to get the product is often prioritized, but this, in
Kimitec 93
of pests. When conditions change, the level product certified, the European Union has a reality, requires special assessment. It is K
Kingbo Biotech 94
of biological and economic performance system called “E-fertilizers”, which we are worth noting the growing problem of using
cheap, unsafe, counterfeit and unregistered Leili 94
L
microbiological biopesticides. Unfortunately,
ORO AGRI 94
O
such business and PR moves, for obvious 94
reasons, have become a significant barrier
Oxiteno
Plant-DiTech 95
to the introduction of truly effective modern P
microbiological biopesticides. Sea6 Energy 95
S
The microbiological pesticides Seipasa 95
registration procedure in Russia is a rather 95
Solvay
long and multi-stage process that takes about
STAPHYT 96
three to four years. Biologicals must undergo
TBIO Crop Science 96
toxicological examination on mammals, fish T
and bees. Then they are tested for biological Tradecorp 96
effectiveness in three climatic zones over two
Zhejiang Sega Science and Technology Co., Ltd 96
Z
years. Environmental and sanitary-hygienic
research on biological products aimed at
determining their effects on the environment
and humans must also be conducted.

Company Directory Company Directory
ASFERTGLOBAL Biolchim SCC – Scientific Consulting

Company
A Azotic Battelle UK
AFEPASA
Azotic has taken more than 20 years of Battelle is the world’s largest nonprofit
academic research and created the first large independent Research and Development
We are a company in constant evolution Biolchim is leader in the production scale, commercially available, consistently organization.
with more than 20 years of accumulated and commercialization of biostimulants and We care for your success
performing nitrogen-fixation product – Our Formulation Development group
experience in the plant nutritional sector. specialty fertilizers designed to optimize Since its establishment in 1989, SCC has
Envita™ (Americas), N-Fix® (UK/EU/Asia). in Havant (UK) has extensive experience &
Our main focus is the development crop production and performance in every been supporting its international customers Azufrera y Fertilizantes Pallarès, Farmers across the globe can reduce synthetic capabilities in formulation development &
of biofertilizers and biostimulants that are agronomic context. With more than 40 years with cost-efficient tailored solutions for their AFEPASA, is a family-owned company that nitrogen fertilizer and maintain yields or testing – including to GLP, where required.
based on the use of microorganisms and new of experience and the close collaboration scientific and regulatory needs within and has more than 125 years of experience in the maintain fertility programs and achieve This encompasses conventional chemical
organic molecules from natural sources as with universities and research centres, outside the EU. handling, packaging and marketing of sulphur higher yields. Finally, there is no compromise fungicides, insecticides & nematicides, plus
part of our innovative and effective solutions Biolchim has developed a complete product Our expertise extends over a broad in its different varieties, and especially in between high yield production agriculture biopesticides, biostimulants and fertilisers.
for the nutrition and care of plants. portfolio of the highest quality based on range of areas, including agrochemicals, its applicability at the agricultural level as a and environmental sustainability. Azotic is For the latter, the on-site Microbiology
The key functions of biofertilizers are to actual market requirements. Based in Italy, and biorationals, fertilisers, chemicals and fungicide, fertilizer and natural biostimulant, experiencing exponential growth with our laboratory works closely with experienced
optimize the soil’s resources allowing better where the production lines and extraction biocides, feed and food additives, food applicable both in conventional agricultural patent protected technology and seek global Formulators to maximise both shelf life
nutrient uptake and yield increase, resulting units are located, Biolchim has seven global contact materials, cosmetics and consumer crops and in those for organic and biodynamic partners to realize our full the potential. & longevity of microbes on treated seeds.
in a reduction of the application of inorganic subsidiaries strategically located in Brazil, products, medical devices, pharmaceuticals farming. Testing capabilities include all properties
chemical-based fertilizers. Germany, Hungary, Poland, New Zealand, and legal services, provided by SCC Legal. This extensive experience, as well as its Nolan Berg required for registration submissions e.g.
We are able to reach local farmers Canada and China, and three representative In the field of biorationals, we offer full- firm commitment to investing in R & D & i President, Azotic North America Ltd. dustiness, drill flow, adhesion, seed loading &
through an international commercial team on offices in Russia, Turkey, and Colombia, scale services for: initiatives, have made AFEPASA the largest [email protected] germination.
the ground, which allows us the possibility through which it builds close partnerships • Biopestides sulphur producer in Europe and the second in 1 877 368 4821 Services list: R&D, Regulatory
to adapt to the diverse range of customer with local distributors and provides • Basic and low-risk substances the world, with an international presence on 001 780 993 7668 Consultancy, Modelling and Testing for
requirements. Currently we are working in continuous technical and sales support on • Biostimulants and fertilisers five continents. Agrochemicals, Biopesticides, Biostimulants,
25 countries which include Spain, France, the territory. In more than 50 other countries, • Soil conditioners, soil aids and plant Also noteworthy is the SULTECH Fertilisers, Development & Testing of new
Greece, Turkey, South Africa, Russia and Biolchim operates through commercial aids technology, developed by AFEPASA, based Formulations, PrecisionAg
USA. partnerships and capillary networks of • Organic/precision farming and IPM. on a microbiological sulphur, more easily B
importers and distributors. For international registrations, we rely on assimilate by the Thiobacteria in the soil and https://www.battelle.org/commercial-
https://www.asfertglobal.com/en/ our corporate offices as well as our partner which allows: offerings/agribusiness/battelle-uk
+351 243 779 431 www.biolchim.it network to offer our customers in-depth and • Transform sulphur into assimilable
Beijing Multigrass Formulation Dominik Reinhard
[email protected] [email protected] up-to-date expertise in their target markets. forms.
Co., Ltd. +44 (0) 7918 259 484
Our offices/ locations: • Faster correction of soil conditions. [email protected]
• SCC Headquarters in Bad Kreuznach, • Generate exudates, which benefits soil
Germany microbiome.
• SCC Berlin
• SCC Japan K.K. www.afepasa.com The basic producer for TC and various
• SCC UK Ltd. +34 977 524 650 formulations:
[email protected] Botanical insecticides, including Matrine,
www.scc-gmbh.de
Rotenone, Pyrethrin
+49 671 298 460
Bio-insecticides, including Spinosad and
[email protected]
Abamectin
Dr Bernd Brielbeck
Plant growth regulator producer, including
GA3 and SABA
Organic fertilizers, including Seaweed
Extract, Humic Acid and Amino Acid
Organic certification by OMRI
GLP data available for registration support
ISO 9001 14001
www.chinabaicao.com
+86-10-65025731
[email protected]

BioBest
C Biorational and certified organic products as
well as Biostimulants. Over many years now
3) Botanical Pesticides
4) Biostimulant NPK Granular fertilizers
Compliance Services
International (CSI)
D
Certis has worked to develop Integrated Crop for soil application
Management programmes using all possible 5) Biostimulant Crop Care & Nutrition
DOGAL PESTICIDES AND
Certis Biologicals products and technologies in different crops, for foliar application
CHEMICALS INDUSTRY
Biobest is a worldwide authority in countries and conditions. The knowledge The above products have been exported
TRADE S.A.
pollination and biological pest control for base across the company provides innovative, to more than 30 countries.
Specialists in Regulatory & Scientific
protected crops and is developing solutions reliable solutions that help farmers and
Consulting since 1988!
for the open field. As the first company ever growers to meet the demands of their markets. www.cdxzy.com
Compliance Services International (CSI)
to commercially supply bumblebees in 1987, Certis is committed to developing and +86-28-85541738
Certis Biologicals is a global specializes in global regulatory and scientific
we continue to lead the way in bumblebee delivering solutions to help European growers [email protected]
manufacturer and distributor of biological consulting services for product registration
pollination. We offer more bumblebee species produce healthy crops in ways that are better
products that meet the needs of partners and and risk assessment for crop protection DOGAL has been manufacturing and
to deal with pollination needs in various for the Earth and good for us all.
growers throughout the world. As a pioneer in (biopesticides/biologicals/biostimulants), exporting plant protection and nutrition
parts of the world than any other supplier. the development of biological pesticides for antimicrobial/biocide, fertilizer, and consumer products since 1989. DOGAL is one
We offer a wide range of hive types for every www.certiseurope.com
commercial agricultural use, we have become products. Our services include International of Turkey’s leading manufacturers of
pollination need, including our patented +31 (0)302 001 200
one of the world’s leading manufacturers regulatory affairs in the USA, EU, Canada, innovative crop protection products that are
Flying Doctors® hive. Natural pollination [email protected]
and distributors of biopesticides, providing LATAM, and Asia pertaining to ecological technologically advanced and scientifically
goes hand in hand with biological control the market with innovative technologies risk assessment / endangered species proven. Our company has a high capacity
of pests and diseases. Our range of products and production expertise spanning from assessment / environmental fate and modeling R&D laboratory and quality systems such as
for biocontrol consists of a large number of fermentation to formulation. Headquartered in / exposure modeling and spatial analysis ISO 9001 and ISO 14001.
beneficial insects, mites and nematodes. We CITYMAX
Columbia, MD, we currently own and operate / study placement and monitoring / data Main Services
also offer monitoring tools, pheromones and two US-based manufacturing facilities and development / endocrine disruptor support • Formulator, manufacturer, distributor
traps. Use our biological solutions with our one international manufacturing facility / toxicology / ecotoxicology / chemistry • Technical support before and after sales
tailor-made technical advice: they make for a through a joint venture. We have the largest consulting / agricultural economic analysis / • Sales and marketing of PPP, plant
strong first line of defense in Integrated Pest number of global registrations of biological litigation / scientific support. nutrition and fertilizer
Management. Let’s work together for People, products and the relationships needed to CITYMAX is Chinese organic fertilizer
Chengdu Newsun Crop Science • R&D (Develops improved formulations
Planet and Profit. deliver those products across a multitude of products manufacturer. We are mainly [email protected]
Co., Ltd. and innovative products)
market segments and geographies. Currently, focusing on production and supply of Humic
www.biobestgroup.com our products are sold in the US and exported acid, Amino acid, Fulvic acid and Seaweed www.dogaltrm.com
+32 14 25 79 80 to more than 50 countries around the world. extract. We own OMRI and ECOCERT listed +90 535 587 07 66
[email protected] products under all product series. Until now, [email protected]
www.certisbio.com we have more than 20 brand distributors
Chengdu Newsun Crop Science Co.,
[email protected] around the world, and have attracted
Ltd. is a biotechnology company focusing on
customers from more than 45 countries and
green agriculture inputs and bio-control. It is
regions. CITYMAX has branch companies in
a leading technology enterprise of botanical
Hongkong, Turkey and Spain. Meanwhile, our
biopesticide in the industry, and also the
USA branch company is under establishment.
advocator and pioneer of green agriculture.
Having fully automatic production line, we
Since its establishment in 1999, Chengdu
are also able to provide multiple kinds of
Newsun has always taken "Revere Nature,
customized products both in liquid form and
Respect Life And Healthy Agriculture"
solid form. Having CITYMAX means having
as its core values, and has always taken
Certis Europe a reliable manufacturer and great service
"Technological Innovation Drives Sustainable
provider.
And Green Agriculture" as its mission, and
has always taken "Ensuring The Quality And
www.citymax-agro.com
Safety Of Agricultural Products, Improving
[email protected]
The Value Of Agricultural Industry And
Certis Europe offers crop protection Improving The Agricultural Ecological
products and expertise to the horticultural, Environment" as the development goal.
speciality and arable crop sectors across Its business line including as below:
Europe. Proprietary products combine with 1) Plant Growth Regulator: Natural
those from a range of supplier partners Brassinolide, Coronatine
(including shareholders) to create a wide- 2) Novel Biostimulant: Pollen
ranging portfolio including conventional, Polysaccharide

E F Futureco Bioscience
I Ingevity
K
Evonik Operations GmbH Fertiliser Consultants Network Idai Nature Kimitec

(FCN) Ingevity provides specialty chemicals,
Founded in 1993 and based in Olèrdola
high-performance carbon materials and
(Barcelona), Futureco Bioscience is an agro-
engineered polymers that purify, protect and
biotechnology company focused on research
enhance the world around us. As the world's
and innovation of products for crop protection
Evonik is one of the world leaders in largest producer of kraft lignosulfonates, Kimitec is a biotechnology multinational
and nutrition. Futureco Bioscience's mission
specialty chemicals. The company is active Idai Nature is a biotechnology Ingevity is committed to quality, consistency company based in Spain and dedicated to
is to lead the change towards regenerative
in more than 100 countries around the world The Fertiliser Consultants Network has company specialised in the development and control in the manufacturing of the research, development and marketing of
agriculture, creating value through scientific
and generated sales of €12.2 billion and an been created in response to the growing need and manufacture of products based on dispersants and surfactant systems. We offer biopesticides, biostimulants, prebiotics and
knowledge and technological innovation.
operating profit (adjusted EBITDA) of €1.91 of the companies, involved in plant nutrition, microorganisms and innovative botanical a range of bio-based specialty inerts for probiotics for the farming industry.
Characterized since its creation by an
billion in 2020. Evonik goes far beyond to expand their market and for the companies extracts with biofungicide, biobactericide plant health and crop protection, and find In 2014, Kimitec set out to become
ecological and sustainable approach, the
chemistry to create innovative, profitable and that do not yet have internal regulatory and/or bioinsecticide effect. customers’ solutions by combining quality the alternative to synthetic chemicals in
company is distinguished by its "in house"
sustainable solutions for customers. More departments. For companies wishing to Idai Nature is one of the most advanced products and unsurpassed technical expertise. agriculture, putting consumer health, respect
organization, developing and manufacturing
than 33,000 employees work together for a expand their business, FCN is able to provide companies in the fields of research and Ingevity’s adjuvant products are sold under for the environment and natural productivity
its products from its own headquarters and
common purpose: We want to improve life assistance in almost all of Europe, North application of new technologies in biocontrol. the brand names AltaHance® and Altastick®. at the heart of agricultural production.
marketing them globally. Futureco Bioscience
today and tomorrow. Africa, South America, Russia, India and R&D&I is the secret formula of the company: Headquartered in North Charleston, South Currently, the company operates in over
is present in 40 countries and has partners,
China. it is our DNA, that which has allowed Carolina, Ingevity operates from 25 locations 90 countries, with branch offices in the USA,
collaborators, and associates all over the
BREAK-THRU® - Surfactant technology New regulations will apply in the us to differentiate ourselves and grow around the world and employs approximately Brazil, LATAM and China, as well as sales
world.
from Evonik European Union and in other important exponentially. Indeed, our name – Idai – is the 1,850 people. offices in Morocco, Hungary, Turkey, Italy,
Futureco Bioscience is specialised in
Countries and it needs to be prepared for new Spanish acronym for Innovative Agricultural the Baltic states, Argentina, India, Russia,
products for biocontrol and biostimulation
We are committed to providing specialty challenges in sectors such as Biostimulants, Research and Development (‘Investigaciones www.Ingevity.com Australia and France.
of agricultural crops, providing to the most
additives to the agricultural industry used as Agronomic Additives and, in general, y Desarrollos Agrícolas Innovadores’). [email protected] In 2019, Kimitec opened its MAAVi
demanding and respectful agriculture, the
spreaders, penetrants, antifoams, emulsifiers Biologicals ; more over the new EU regulation We develop exclusive formulas suitable Innovation Center, the largest center dedicated
tools to produce with quality, safety, and
and dispersants in tank mix applications on Mutual Recognition has also come into for all types of agriculture through our own to the research and development of natural
respect for the environment.
as well as in crop protection formulations. force. natural technology, enabling our clients to products for the farming industry in Europe,
With an emphasis on innovative solutions, Highly specialised local experts increase their profitability and obtain safe and one of the largest biotechnology centers
https://www.futurecobioscience.com/en/
we offer agricultural solutions based on both with knowledge of both national and EU food suitable for all markets. for natural agriculture in the world.
+34 938 182 891
siloxane and organic surfactants under the regulations can adequately assist companies From MAAVi, Kimitec assists
[email protected]
BREAKTHRU® brand name. wishing to take advantage of these new www.idainature.com agrochemical companies, big producers
opportunities. +34 961 661 414 and well-known food brands in becoming
Contact us on: The FCN will also attend to the most [email protected] “greener”, helping them to produce tastier,
EMEA important international events on plants INTERMAG healthier and more sustainable foods through
+49 201 173 2665 nutrition and will organise advanced courses disruptive technologies.
+49 301 173 1990 on regulatory issues.
https://kimitec.com/
Americas www.fertcon.net +34 950 34 69 09
+1 804 727 0700 [email protected] INTERMAG is a company founded [email protected]
+1 804 727 0855 in Poland in 1988. From the beginning,
its activity focused on the development
Asia | Pacific and production of modern preparations for
+86 21 6119-1125 agriculture. Currently the company is one of
+86 21 6119-1406 the biggest manufacturers of fertilizers and
www.evonik.com/break-thru biostimulants, and actively participates in the
[email protected] sector of animal health products. INTERMAG
has expanded its operations in Europe, Asia,
Africa, North, and South America.
https://intermag.eu/
[email protected]

Kingbo Biotech
O Oxiteno
P S Seipasa
ORO AGRI Plant-DiTech Sea6 Energy

Kingbo Biotech was established in 1992, Oxiteno is one of the world’s leading Seipasa is a pioneering Spanish company
we are a professional production company in surfactant companies, headquartered in Sao in biotechnology applied to agriculture. It
organic botanical products. We are specialized Paulo, Brazil. It has a global reach and is designs, registers, markets and sells solutions
in utilizing the advanced technology of focused on developing new molecules and of botanical and microbiological origin for
extraction and combining with the Chinese ORO AGRI develops and manufactures technologies to serve demands and major More than meets the eyes: Discover the Sea6 Energy is a pioneer of innovative crop protection, biostimulation and nutrition
traditional insecticidal, bactericidal and patented products for agricultural, home, trends in the markets it operates in. underlying secrets of plants performance technologies for large-scale mechanized worldwide. Its products are exported to more
antiviral herbs, we provide plant protection and industrial applications worldwide. We The Crop Solutions division has Plant-DiTech is introducing the ocean farming and products derived from than 25 countries in the world.
technology and a full range of services specialize in products that provide effective more than 40 years of experience in the PlantArray platform which enables ag- tropical red seaweeds. The company has fully
for all organic agriculture and ecological yet residue-free solutions to our clients’ pest agrochemical market. It develops custom researchers from Food, Chemical, and integrated the upstream and downstream www.seipasa.com
agricultural producers. We devote ourselves control challenges. ORO AGRI develops, solutions develop more robust adjuvant BioAg companies, as well as scientists from value chain from seaweed cultivation to [email protected]
to organic farming for over 20 years, focus on and distributes a portfolio of products that tank mix solutions to increase yield for research institutes, to efficiently screen plants manufacturing of end products, using its
food safety, we are modern organic farming includes biopesticides, adjuvants, soil active ingredients and adjuvants that support response to different stresses, measuring key expertise in engineering design, marine
pioneer and advocate. conditioners, bio stimulants, foliar fertilizers, compatibility for different products. functional growth and productivity traits (e.g. agronomy, offshore infrastructure, process
and postharvest products. We are present in Crop Solutions is focused on improving transpiration, biomass, water and nutrients- engineering and product development. This
http://www.kingbo.com.cn/ more than 90 countries, having factories on crop yields and nutrient availability through use-efficiencies, root activity), together with ecosystem includes patented technologies Solvay
0086-10-65076301 (Landline) four continents, and state-of-the-art science new technologies, using fewer natural environmental measurements, achieving like SeaCombine®, a fully mechanized sea
15901258363 (Mobile) and research centers in Brazil, Europe, the resources (water and land). This is how high-quality results, saving up to 80% of the tractor and Dweep®, floating structures that
[email protected] U.S.A., and South Africa. Oxiteno helps to feed the world and reduces screening costs & time with a much faster supply renewable offshore power for both the
Our research database contains more environmental and social impacts with the new product market introductions by at least SeaCombine as well as nutrient upwelling
than 2000 field trial studies, including efficient use of natural resources. 1-3 years. systems integral to ocean farming. The
Founded in 1863, Solvay is a science
L contributions from over 500 universities and
research consulting groups. This research
Based on its in-depth knowledge of
market needs and trends, Crop Solutions has
Plant-DiTech is a patented technology,
with over 30 academic articles using the
company’s research focus in biotechnology
enabled development of novel and patented
company developing materials, chemicals
identified four major innovation platforms and solutions for medical and consumer
has led to over 200 patent applications, 22 PlantArray solution, and distinguished product portfolio comprising plant
and develops new technologies in each one of goods, electronics, cars, planes, construction,
patents, 68 biopesticide product registration customers such as Wageningen Research biostimulants and biodefense products, animal
Leili certificates, more than 100 pending them: Crop Protection; Tank Mix Adjuvants, & University, ICL, Haifa Chemicals, Mars health products, human food ingredients,
manufacturing, food and agriculture. Our
Biosolutions and Crop Enhancement. purpose is to bond people, ideas and elements
registration certificates, and over 1500 Wrigley, and many others. The company is biodegradable plastics and fuel. Sea6
to reinvent progress, through an ambitious
granted applications for various trademarks a spin-off from the Hebrew University of Energy has been featured in the "Uplink"
www.oxiteno.com sustainability plan crafted around three
and slogans. Jerusalem, the faculty of agriculture, Israel. platform, World Economic forum as one of
[email protected] pillars: protecting the climate, preserving
ORO AGRI investment in innovation the top Ocean innovators and was awarded
resources and improving people's life.
and R&D combines science with natural www.Plant-DiTech.com "Emerging company of the year - Agriculture"
Established in 1993, Leili is a hightech Along the agricultural value chain,
and renewable resources to create safe and +972 (8) 699-9169 and "Promising Agritech Startup" in India.
group companies professional in research, Solvay solutions help farmers increase crop
environmentally friendly crop protection and [email protected] Our biostimulant product was the finalist in
production and marketing of innovative yield in a sustainable way. In crop protection,
yield improvement solutions for the global the "Best New Biological Product" category
marine resources product. Leili owns our greener, safer formulation additives
agricultural and consumer markets. At its at Agrow Awards and the founders received a
independent technology on enzymatic enhance efficacy and on-target delivery
core, ORO AGRI has always been science special mention in "30 under 30" category by
extraction of algae, and enzymatic extraction of actives. In plant nutrition, our nitrogen
powered by nature! Forbes magazine.
of dual algal polysaccharide. Leili series inhibitors increase fertilizer availability to
biostimulant products and solutions cover the the plant while reducing greenhouse gas
www.oroagri.eu www.sea6energy.com
function of bioregulation, crop quantity and emissions and water pollution. In seed care,
+31 508200411 +91 80 23623400 (Landline)
health improvement, and stress resistance, we innovate with plant-based biostimulants to
[email protected] +91 7349612718 (Mobile)
etc. Leili has built a wide network of supports protect crops from drought and climate stress
[email protected]
and services of the biostimulants application and natural binders for on-seed applications
in over 80 countries. The core products of of future actives and biocontrols.
Leili has been attested by Ecocert and listed Experts in the field for over 40 years,
in REACH of Europe. Solvay Agro teams create bonds to change the
future of Agriculture.
www.leili.com
+86-10-68910636 www.solvay.com
[email protected] +33 1 5356 5178
[email protected]

Company Directory Interviews
STAPHYT
T www.tradecorp.com.es
+ 34 91 3273200
[email protected]
TBIO Crop Science
Contract Research Organisation, Staphyt

was created in 1989.
Staphyt provides services in Agrosciences Z
and Regulatory Affairs in Europe, Australasia TBIO is a biostimulants supplier already
and beyond through partners. in the Humic, Amino, Seaweed area for over
We offer reliable solutions and high 20 years, always provides the top quality
Zhejiang Sega Science and
levels of expertise to agrochemicals, product for our customers with the best
Technology Co., Ltd
biologicals and seeds breeding companies for service. That’s why we are a high reputation
the development, registration and promotion in Spain, France, Italy, and Europe. TBIO
of their products. Our areas of expertise are has various organic certificates like CERES
agricultural experimentation, regulatory (for EU), OMRI (for the USA), also REACH
consultancy, coordination of registration (permission for EU), and the only China
dossiers in plant-protection and nutrition. Zhejiang Sega Science and Technology
member in the EBIC list.
We provide a full range of services, such Co., Ltd is a high-tech enterprise focusing
as: on the research, development, production
www.tbio.cn
- Biological field studies (GEP) and sales of pesticides and Biostimulant. The
[email protected]
- Controlled conditions studies in company’s main products include agricultural
laboratory and glasshouse pesticides, Plant Growth Regulator,
- Crops safety and field residue studies Biostimulant, Forestry pests and diseases
(GLP) prevention and control, Surfactant etc.
- Ecotoxicology studies The company has a large number of
- Seeds studies pesticides and Biostimulant registrations,
- Regulatory Affairs services with complete certificates, and covers most
Tradecorp agricultural compounds and the prevention
The strength of our network combined
with the expertise of our people guarantees and control of plant diseases, insects and
the success of studies, in complete safety and weeds. It can meet the requirement for
within deadlines. different regions and different crops use
These key points evidence our ability to of plant growth regulators, crop nutrition,
provide the best quality service and capacity Tradecorp is a global benchmark in the pesticides, forestry prevention, public health
to succeed with your trials, their management development and manufacture of premier and gardening product etc.
and registration issues. innovative Biostimulation solutions and Crop Main products including:
Staphyt is fully engaged with its clients to Nutrition specialities, which are marketed 1) PGR: Brassinolide, S-Abscisic acid,
actively support their innovation, growth and in over 60 countries worldwide. Tradecorp Gibberellic acid
future success. provides a comprehensive, premium portfolio 2) Biostimulant:
of products globally adapted to local Arbuscular mycorrhiza
www.staphyt.com agronomic conditions, comprising solutions Co-cultivation of Trichoderma
+33 (0)3 21 21 45 21 such as biostimulants, chelates, and precision Asperellum&Bacillus amyloliquefaciens
[email protected] foliar fertilizers. 3) Bio insecticides: Abamectin,
The recent acquisitions of Microquimica, Eamemctin benzoate
in Brazil, and SDP, in France, have led to 4) Insect pheromone: sex attractant
unprecedented growth in the company and 5) Other chemical pesticides
added extra value to Tradecorp’s portfolio, 6) Synergist: Organic silicon adjuvant,
incorporating microbiological solutions, such Plant oil adjuvant
as inoculants and bacterial extracts, along
with cutting-edge adjuvants. In addition, the www.segaagro.com
recent acquisition of Rodel Flowers has given +86-571-87245132 (Landline)
Tradecorp a new direct connection to the end +86-13819136280 (Mobile)
user in Ecuador. [email protected] (Peter Xu)

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Interviews

2021 Biologicals Special 1

SCC Scientific Consulting Company

2 2021 Biologicals Special 2021 Biologicals Special 3

Agri Star S.A. P52

partners Beijing Kingbo Biotech Co., Ltd. P85

Beijing Multigrass Formulation Co., Ltd. Inside Front Cover

Biobest Belgium N.V. P70

Biolchim S.p.A. P11

Compliance Services International (CSI) P91

Leili Marine BioIndustry INC. P21

Lim-Loges & Masters Pte Ltd. P57

Oro Agri P31

Scientific Consulting Company (SCC) P1

Sea6 Energy P18

Sino Agro-Chemical Industry Ltd. P69

The Core and Changes in Registration Regulation for Biopesticides and

Asfertglobal is a leading Portuguese company in

P12 Interviews P43 Idai Nature, France Launches PORTENTO® to

P44 The Global Expansion of Certis Biologicals Viewpoints

Asfertglobal Expands in International

Asfertglobal is a leading Portuguese company in

Today we are attentive to sustainable agriculture and

The European Commission aims to reduce by 50% the use of

8 2021 Biologicals Special 2021 Biologicals Special 9

10 2021 Biologicals Special 25

Biolchim’s Way to Face Divers,

12 2021 Biologicals Special 2021 Biologicals Special 13

14 2021 Biologicals Special 2021 Biologicals Special 15

What advantages are offered by microbiological Sulphur over other

16 2021 Biologicals Special 2021 Biologicals Special 17

Research and Superior Agronomy Expertise

18 2021 Biologicals Special 2021 Biologicals Special 19

What are the things that Sea6

Here is our expectation checklist -

20 2021 Biologicals Special

2021.5.14 Agropage 半版广告 - bio 第二版 - 英文版[转曲].indd 1 2021/6/4 10:09:04

Working Together to Create a 3B joint creation of this new era?

Since its establishment, Leili has focused

New Era, Establish a Balanced

Agricultural Value Community and application. The term, 3B, refers to

22 2021 Biologicals Special 2021 Biologicals Special 23

24 2021 Biologicals Special 2021 Biologicals Special 25

in Key Markets: EU, US, India and Japan

26 2021 Biologicals Special 2021 Biologicals Special 27

28 2021 Biologicals Special 2021 Biologicals Special 29

Biostimulant registration and trends in Japan

Biostimulants are not legally defined in Japan. However,

Trends and developments in the Japanese biopesticide market

30 2021 Biologicals Special

Biopesticide Active Ingredients Get

Policy Support for Entrance into

Chinese Market as to their classification as biopesticides.

32 2021 Biologicals Special 2021 Biologicals Special 33

Table 1. Active ingredients of microbial pesticides, biochemical pesticides,

Metarhizium anisopliae , Beauveria bassiana , Trichoderma harzianum , Paecilomyces lilacinus , Verticillium

Other Cholecal ciferol

Insecticide Abamectin, spinosad, ivermectin

Greening up the Future of