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    Lip Diseases

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    ريام الموسوي
    This document summarizes several lip diseases and lesions including actinic cheilitis, cheilitis glandularis, cheilitis granulomatosa, Melkersson-Rosenthal syndrome, exfoliative cheilitis, median lip fissure, double lip, and angioneurotic edema. For each condition, it provides definitions, etiologies, clinical features, diagnostic methods, differential diagnoses, and typical treatments. The conditions range from premalignant sun-induced lesions to rare inflammatory disorders to allergic reactions involving lip swelling. Histopathological examination and clinical examination are relied upon for diagnoses, while treatments include sun protection, steroids, surgery, and antihistamines depending on the specific condition.

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    Lip Diseases

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    ريام الموسوي
    115 views13 pages
    This document summarizes several lip diseases and lesions including actinic cheilitis, cheilitis glandularis, cheilitis granulomatosa, Melkersson-Rosenthal syndrome, exfoliative cheilitis, median lip fissure, double lip, and angioneurotic edema. For each condition, it provides definitions, etiologies, clinical features, diagnostic methods, differential diagnoses, and typical treatments. The conditions range from premalignant sun-induced lesions to rare inflammatory disorders to allergic reactions involving lip swelling. Histopathological examination and clinical examination are relied upon for diagnoses, while treatments include sun protection, steroids, surgery, and antihistamines depending on the specific condition.

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    This document summarizes several lip diseases and lesions including actinic cheilitis, cheilitis glandularis, cheilitis granulomatosa, Melkersson-Rosenthal syndrome, exfoliative cheilitis, median lip fissure, double lip, and angioneurotic edema. For each condition, it provides definitions, etiologies, clinical features, diagnostic methods, differential diagnoses, and typical treatments. The conditions range from premalignant sun-induced lesions to rare inflammatory disorders to allergic reactions involving lip swelling. Histopathological examination and clinical examination are relied upon for diagnoses, while treatments include sun protection, steroids, surgery, and antihistamines depending on the specific condition.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    115 views13 pages

    Lip Diseases

    Uploaded by

    ريام الموسوي
    This document summarizes several lip diseases and lesions including actinic cheilitis, cheilitis glandularis, cheilitis granulomatosa, Melkersson-Rosenthal syndrome, exfoliative cheilitis, median lip fissure, double lip, and angioneurotic edema. For each condition, it provides definitions, etiologies, clinical features, diagnostic methods, differential diagnoses, and typical treatments. The conditions range from premalignant sun-induced lesions to rare inflammatory disorders to allergic reactions involving lip swelling. Histopathological examination and clinical examination are relied upon for diagnoses, while treatments include sun protection, steroids, surgery, and antihistamines depending on the specific condition.

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    © All Rights Reserved
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    of 13

    Lip diseases

    Lip Lesions
    • Actinic Cheilitis
    • Definition Actinic cheilitis is a chronic degenerative disorder of
    the lower lip.
    • Etiology Long-term exposure to sun light.
    • Clinical features In the early stage, mild erythema and edema
    followed by dryness and fine scaling of the lower lip vermilion
    border are the presenting signs. As the lesion progresses, the
    epithelium becomes thin and smooth, with small whitish-gray
    areas with red regions and scaly formations. Erosions and tiny
    nodules may develop. The lesion is premalignant, and usually
    occurs in men over 50 years of age.
    • Laboratory tests Histopathological examination.
    • Differential diagnosis Leukoplakia, lichen planus, lupus
    erythematosus, early squamous-cell carcinoma, cheilitis due to
    radiation.
    • Treatment Protection of lips from sunlight. Vermilionectomy in
    severe cases.
    • Cheilitis Glandularis
    • Definition Cheilitis glandularis is an uncommon chronic inflammatory
    • condition of the minor salivary glands, characteristically affecting the lower lip.
    • Etiology Unknown.
    • Clinical features It presents as a swelling of the lower lip due to hyperplasia and
    inflammation of the glands. Characteristically, the orifices of the salivary glands are
    dilated, and pressure on the lip may produce mucous or mucopustular fluid from
    the ductal openings. Crusting and erosions may also occur.
    • Laboratory tests Histopathological examination.
    • Differential diagnosis Cheilitis granulomatosa, Melkersson–Rosenthal syndrome,
    Crohn disease, sarcoidosis, cystic fibrosis.
    • Treatment Supportive. Vermilionectomy only in severe cases.
    • Cheilitis Granulomatosa
    • Definition Cheilitis granulomatosa is a rare chronic
    disorder of the lips.
    • Etiology Unknown.
    • Clinical features It presents as a painless, persistent,
    and diffuse swelling of one or both lips, small vesicles,
    erosions, and scaling may occur. It is thought that cheilitis
    granulomatosa is a monosymptomatic form of
    Melkersson–Rosenthal syndrome.
    • Laboratory tests Histopathological examination.
    • Differential diagnosis Cheilitis glandularis, Crohn
    disease, sarcoidosis, cystic fibrosis, lymphangioma,
    angioneurotic edema.
    • Treatment Topical or systemic steroids, tetracyclines.
    Plastic surgery in severe cases.
    • Melkersson–Rosenthal Syndrome
    • Melkersson–Rosenthal syndrome is a rare disorder characterized by
    • cheilitis granulomatosa, facial paralysis, fissured tongue, and less
    often intraoral and facial edema.
    • The term “orofacial granulomatosis” has recently been proposed to
    include conditions and diseases characterized by granulomatous
    inflammation in the oral and facial area (cheilitis granulomatosa,
    Melkersson–Rosenthal syndrome, Crohn disease, sarcoidosis).
    • The differential diagnosis and treatment are identical to those
    of cheilitis granulomatosa.
    • Exfoliative Cheilitis
    • Definition Exfoliative cheilitis is a chronic inflammatory disorder of
    the lips.
    • Etiology Unknown.
    • Clinical features It is characterized by scaling, crusting, and erythema
    of the vermilion border of the lips, resulting in yellowish,
    hyperkeratotic thickening, crusting, and fissuring.
    • The lesions are more common in young women, usually persist with
    variable severity for months or years, and may cause cosmetic
    problems.
    • The diagnosis is based on the clinical findings.
    • Differential diagnosis Contact cheilitis, actinic cheilitis.
    • Treatment Symptomatic. Topical moistening agents and steroids may
    be helpful. Topical ointment of tacrolimus 0.1% may be helpful.
    • Median Lip Fissure
    • Definition Median lip fissure is a relatively rare disorder that may
    appear in the lower or upper lip.
    • Etiology Unclear.
    • Clinical features It presents as a deep, inflammatory, persistent
    vertical fissure at the middle of the lip, usually infected by Candida
    albicans and bacteria. Spontaneous bleeding, discomfort, and pain
    are common. The diagnosis is based on the clinical findings.
    • Treatment Topical steroids with or without antifungal agents and
    antibiotics. Plastic reconstruction in severe cases.
    Double lip is a malformation characterized by a
    protruding horizontal fold of the inner surface of
    the upper lip. It may be congenital, but it
    can also occur as a result of trauma. The abnormality
    becomes prominent during speech or smiling.
    Treated by surgical correction for esthetic reasons only.
    • Angioneurotic Edema
    • Definition Angioneurotic edema is a relatively common allergic
    disorder.
    • Etiology Inherited or acquired (food allergy, chemicals, infections,
    stress).
    • Clinical features It characteristically has a sudden onset, and lasts for
    24–48 hours. The lesion presents as a painless, smooth swelling of
    the lips. Other intraoral regions and the glottis may also be involved.
    • The diagnosis is usually based on the clinical findings.
    • Differential diagnosis Cheilitis granulomatosa, emphysema, cellulitis.
    • Treatment Antihistamines,
    systemic steroids.

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